Supplementary Table 1: Comparison of basic data collected in CLARITY younger
diagnosed and older diagnosed cases.
Younger diagnosed Cases
(≤ 6 years)
n†
Older diagnosed Cases
(> 6 years)
n†
118
99
116
107
73.7%*
86.9%
38.4 (SD: 5.8)*
41.3 (SD: 6.4)*
137
114
133
130
59.9%
86.8%
41.8 (SD: 5.7)
44.5 (6.4)
Mother’s SEIFA§ score
Father’s SEIFA§ score
Mother’s education
37
32
1027.0 (SD: 69.2)
1034.7 (SD: 59.7)
50
47
1024.6 (SD: 59.3)
1017.8 (SD: 67.2)
Completed year 12
Completed postgraduate degree
Father’s education
Completed year 12
Completed postgraduate degree
Mother’s marital status at interview
married
divorced
separated
widowed
de facto
never married
Father’s marital status at interview
married
divorced
separated
widowed
de facto
never married
don’t know
Mother hours in paid work (mean)
Father hours in paid work (mean)
Mother cigarettes/day
none
1-10/day
11-20/day
21-40/day
41+/day
Father cigarettes/day
none
1-10/day
11-20/day
21-40/day
41+/day
Mother alcoholic drinks/wk mean (SD)
Father alcoholic drinks/wk mean (SD)
117
85
72.7%
8.2%
133
112
60.9%
11.6%
110
79
116
59.1%
11.4%
129
97
133
55.0%
13.4%
Basic characteristics
Child female
Child has four Caucasian grandparents
Mother’s age at interview
Father’s age at interview
Socio-demographic data
81.9%
5.2%
4.3%
0.9%
0.9%
6.9%
110
97
93
116
77.4%
8.3%
6.0%
0.8%
3.0%
4.5%
131
89.1%
3.6%
2.7%
0.0%
0.0%
4.6%
0.0%
19.0 (SD: 18.0)
43.5 (SD: 15.4)
116
118
132
81.0%
8.6%
7.8%
2.6%
0%
110
80.2%
7.6%
4.6%
1.5%
2.3%
3.1%
0.8%
25.3 (SD: 20.7)
42.5 (SD: 15.3)
78.8%
11.4%
8.3%
1.5%
0%
127
112
107
81.8%
6.4%
9.1%
2.7%
0.0%
2.4 (SD: 4.2)
4.4 (SD: 5.5)
130
120
74.8%
9.5%
11.0%
3.2%
1.6%
2.1 (SD: 3.5)
5.4 (SD: 7.6)
116
31.1 (SD: 4.7)*
133
29.5 (SD: 5.1)
Pregnancy & Birth
Mother’s age at childbirth (mean, yrs)
Father’s age at childbirth (mean, yrs)
Planned pregnancy
planned natural
planned assisted
unplanned
Child adopted
Mother smoked during this pregnancy
Nil
Less than daily
1-10/day
11-20/day
21-40/day
41+/day
Father smoked during this pregnancy
Nil
Less than daily
1-10/day
11-20/day
21-40/day
41+/day
Mother major illness during pregnancy
Mother meds/supps during pregnancy
multivitamins
folate
calcium
iron
vitamin D
fish oil
antibiotics
other
Mother any alcohol during pregnancy
Mother any coffee during pregnancy
Child’s gestation (mean, weeks)
Child mode of delivery
normal vaginal
assisted vaginal
caesarian
other
107
118
Child birthweight (mean, g)
Child birthlength (mean, cm)
Child head circumference (mean, cm)
Child in multiple birth
Child birth order (all live-born sibs) mean
105
92
77
115
118
3361.1 (SD: 533.8)
50.1 (SD: 2.6)
35.0 (SD: 3.4)
0.9%*
1.9 (SD:1.1)
114
97
80
131
137
3358.3 (SD: 685.0)
50.2 (SD: 4.0)
34.7 (SD: 2.7)
6.1%
1.9 (SD: 1.0)
any
if any, age started (wks) (mean, SD)
if any, weeks breastfed (mean, SD)
Child formula feeding
age started (weeks)
weeks formula fed
Child cow’s milk commence age (weeks)
Child solids commence age (weeks)
117
104
103
90.6%
0.4 (SD 1.7)
39.3 (SD 32.1)
136
109
107
82.4%
0.3 (SD 1.6)
34.1 (SD 27.9)
81
106
102
109
19.8 (SD 20.1)
32.7 (SD 39.6)
59.3 (SD 17.1)
22.4 (SD 5.4)
108
127
114
119
17.3 (SD 20.0)
37.4 (29.9)
58.6 (SD 18.4)
25.9 (SD 21.9)
Mother smokes indoors near child
109
137
116
34.1 (SD: 5.7)*
80.5%
72.0%
8.5%
19.5%
0%
130
137
118
133
83.6%
8.6%
3.5%
3.5%
0.9%
0%
107
118
115
116
116
116
116
116
116
115
114
114
99
37
32.2 (SD: 5.7)
78.8%
74.5%
4.4%
21.2%
0%
84.2%
3.8%
8.3%
3.8%
0%
0%
123
82.2%
1.9%
5.6%
8.4%
1.9%
0.0%
29.6%
28.7%
69.0%
12.7%
30.2%
4.3%
4.3%
3.5%
13.9%
19.3%
57.0%
39.4 (SD: 1.6)
136
123
123
123
123
123
123
123
122
134
132
107
50
64.9%
10.8%
21.6%
2.7%
71.5%
4.1%
4.9%
13.8%
4.9%
0.8%
22.1%
21.1%
55.3%
8.9%
39.0%
2.4%
1.6%
4.1%
8.2%
17.2%
54.6%
39.2 (SD: 2.0)
62.0%
14.0%
24.0%
0%
Early Life
Child breastfeeding
usually
sometimes
125
0.0%
1.8%
1.6%
5.6%
never
Father smokes indoors near child
98.2%
103
usually
sometimes
never
92.8%
123
0.0%
1.0%
99.0%*
2.4%
5.7%
91.9%
† Number of observations
* p < 0.05 vs older diagnosed cases by unadjusted logistic regression. See text for outcomes of adjusted
analyses.
§ SEIFA = Socio-Economic Indexes for Areas, a measure of residential positional disadvantage based on the
Australian Bureau of Statistics Census of Population and Housing. The higher the score, the lower the
disadvantage.