CCTRP Proposal #: (leave blank) The 2016 Case-Coulter Translational Research Partnership Pre-Proposal Template (Replace with Your Title) This is a template for your pre-proposal. More information on each of the sections is described below, along with a benchmark length for each. Please replace the descriptive text included in this template with your own. The font cannot be smaller than 11 point and must be Arial. Line spacing is no less than single and margins no less than half an inch. Figures are allowable but are included in the page limitation of two pages. It is recommended to include a figure that clearly and memorably describes your technology (picture of prototype, flow chart, key preliminary data, etc.). Please note that the CCTRP and Technology Transfer offices are more than willing to meet with you to provide guidance. Team – This section should be about ¼ of a page and should describe who the team members are, what each brings to the project, and what their roles will be. Please underline the names of the team members. Be sure to include any past translational/commercialization experience. Figure 1. Sample Figure Clinical Need – This section should be about ¼ of a page and should describe what the unmet clinical need is. If you have verified this need by conversations with clinicians or other, this would be good to include. Useful questions to address include: What is the clinical problem your technology will address? What is the current standard of care and why is it not ideal? Technology & Value Proposition – This section should be about ¼ of a page and should succinctly describe your technology and why someone would want to buy/use your technology. It may be helpful to think of this section as your “elevator pitch” for the technology. Useful questions to address include: What is the benefit to patient care? What is the effect on the cost of care? Why would a patient/provider/payer have interest in this? Why would a business person/investor have interest in this? Market for Technology – This section should be about ¼ of a page and should describe the overall market for your technology as well as the specific market segments you will address. The market opportunity should be quantified by multiplying the estimated number of units that could be sold in a year (assuming you sold to every customer) by the estimated sales price. Useful questions to address include: Who will use your technology? Who will pay for you technology? Which patients will benefit from your technology? While it is good to include the overall “swimming pool” for your technology (i.e. coronary artery disease has a 16 million prevalence), it is important to segment down to what your device will address (i.e. drug eluting stents has a 0.75 million prevalence). In this example, if your technology was a drug eluting stent that you expected to sell for $2000, your market opportunity as previously described would be $1.5 billion. If you are unsure about these numbers, we encourage you to work with the CCTRP and/or Technology Transfer offices. There is no minimum market size for inclusion in the CCTRP program, so it is more important that the market be accurate than large. 2016 Case-Coulter Translational Research Project Pre-Proposal Page 1 of 2 (2 page maximum) CCTRP Proposal #: (leave blank) Project Milestones – This should be the longest section of the pre-proposal and should describe the project plan in about ½ page. This section should be segmented into milestones, with the typical proposal including 23 milestones. A sample (but overly brief) milestones providing a sample format is below. Include in each milestone why it is critical to the development of your technology (as opposed to others you could propose). Milestone 1: Provide a template for the pre-proposal. A template (this template in fact) will be assembled and approved by the review committee. The template will be attached to the RFA and posted on our website for easy access. It is critical to provide this template to make this process as easy and as productive as possible for both proposers and reviewers. We expect this milestone will take less than one quarter. Competition – This section should be about ¼ of a page and should describe any technologies that are competitive to yours, either on the market or in development. For each competitor, please describe the strengths and weaknesses of your technology compared to the competitor. It is possible for some new technologies to not direct competitors, but they likely will have some standard that they are replacing, and this can be used as the competitor. IP & Commercialization Status – The final section should be about ¼ of a page and should describe the status of your IP related to this technology (invention disclosures, provisional patent applications, full patent applications, patents). If you have any patents awarded (not very common at this stage), include very briefly what the patent claims cover. In terms of commercialization status, if you have had any interactions with any potential acquirer please describe. 2016 Case-Coulter Translational Research Project Pre-Proposal Page 2 of 2 (2 page maximum)