CS-34
5/23/2016 2:30:00 PM - 5/23/2016 4:00:00 PM
Hepatitis, Hemochromatosis and Drug Induced Liver Injury- 3 Liver diseases that Break the Mold
This session is designed to provide the attendee with the basic information needed to tackle some common liver
diseases that are commonly seen. It will cover Hepatitis, Hemochromatosis, and Drug Induced Liver Injury. We will
review the most commonly encountered types of Hepatitis, signs and symptoms of cirrhosis, and will also briefly
describe some of the complications from NASH. From Hepatitis and NASH we will move on to Hemochromatosis where
we will review the at risk populations for the disease, signs and symptoms of the disease, and the treatment and
prognosis. Last, but not least, we will discuss Drug-Induced Liver Injury, a common and often frightening condition. We
will review the type of DILI, the most common drugs involved in DILI, treatment for DILI, and how to educate our
patients on how to prevent DILI.
Objective
Content
Time
Frame
Presenter
Define types of
hepatitis, common
signs and sx of
hepatitis, and signs and
sx of cirrhosis).
Definitions and types of hepatitis- acute
and chronic
Hepatic damage- signs and symptoms,
risks, progression
Brief overview of drugs and herbs
associated with hepatitis
Risks for chronic hepatitis
Hepatitis: Function, abnormal labs,
hepatic system review"
Question/Answer
Identify who is at risk for Hemochromatosis
7 minutes
1 metabolic disorder
2 hereditary
3 onset of the disease
Discuss sign and symptoms of
hemochromatosis
10 minutes
1 diagnosis of disease
2 signs and symptoms
3 risk for other diseases
Treatment of disease and prognosis
8 minutes
1 phlebotomy
2 foods to avoid
Objective 2 Discuss sign and symptoms of
hemochromatosis
10 minutes
1 diagnosis of disease
2 signs and symptoms
3 risk for other diseases
Objective 3 list treatment of disease and
prognosis
8 minutes
1 phlebotomy
2 foods to avoid
Identify common medications/drugs
that are known to cause liver injury ( 5
minutes)
A. Common medications known to cause
30
minutes
Ann Marie Hunt
Bellah, RN,
MSN,FNP-c
30
minutes
Katherine Vinci
RNC, CGRN
15
minutes
Cynthia Escusar,
RN, BSN and
Simran Tagore, RN,
MSN, NP-c
Identify who is at risk
for Hemochromatosis,
discuss sign and
symptoms of
hemochromatosis, list
treatment of disease
and prognosis.
Identify common
medications/drugs that
cause liver injury and
common signs and
GI
Not GI
symptoms of DILI and
lab abnormalities.
Discuss possible
treatment options for
DILI and education to
our patients regarding
drug safety and how to
avoid DILI.
DILI
- Most commonly knownAcetaminophen
- Antibiotics
- Analgesics
- Supplements and Herbs
- If unsure of a drug’s hepatoxic effects,
where to find out/resources
B. Diagnose DILI by recognizing common
signs and symptoms of DILI and lab
abnormalities (8 minutes)
- May have DILI before onset of sx
- May have sx of liver disease- nausea,
fatigue, anorexia, jaundice, RUQ
pain/discomfort, dark urine, itching
- ALT, AST, T bIli, Alk phos
- Patterns of LFT’s and type of drug
injury
Discuss possible treatment options
for DILI and education to our
patients regarding drug safety and
how to avoid DILI"
A. Withdrawal of the offending
drug
- Early recognition of drug toxicity is
key
B. Meds
- Glucocorticoids
- Bile acid sequestrant
- Monitor labs
C. Prognosis
D. Educate patients on the
medications they are taking and for
what conditions
- Handouts from American Liver
Foundation
- Question and Answer
15
minutes
Simran Tagore, RN,
MSN, NP-c
Total