GENERAL PATH TEST
BOARD REVIEW LISA MAYO, RDH
1. Pleuropneumonia-like organisms, mycoplasmas, severe systemic complications, and a triad
of symptom locations (oral,eye,genital) in a male patient are specifically indicative of
a. Erythema multiforme
b. Stevens-Johnson syndrome
c. Behcet’s syndrome
d. Recurrent aphthous stomatitis
e. AIDS
A: has a “bulls eye” skin lesion
B: severe form of erythema multiforme
D: has oral lesions, but not eye or genital
E: not related to this description
2. The histology reports for clinical leukoplakia could show any of the following EXCEPT
a. Dyskeratosis
b. Acanthosis
c. Large nuclei
d. Some necrosis
e. Osteoclasts
E: involved in bone formation.
3. Which of the following is very characteristic of pemphigus valgaris?
a. Nikolsky’s sign
b. Black females
c. Drug reaction etiology
d. White males
e. Positive rabbit eye test
A: use an A/W syringe to “blow” the epithelium away from connective tissue, one of the most
characteristic signs in PV
B: there is no gender or age in PV
C: etiology unknown or may be viral
E: test is for herpes
4. A platelet count of 150,00-400,00mm3 of blood could not be indicative
a. thrombocytopenia
b. anemia
c. Leukemia
d. Non-thrombocytopenia purpura
e. mononucleosis
B: RBC decreased
C: increase WBC
D: Platelet count is normal. Bleeding tendency is a result of the fragility of capillary walls
E: increase total WBC count. Cells called Downey cells are found in abundance. Can be
mistake for leukemia but the Paul-Bunnell heterophil test will be positive.
5. The MOST accepted theory in the etiology of Behcet’s syndrome is:
a. Viral origin
b. Metabolic origin
c. Pleuropneumonia like organisms
d. Hormonal origin
e. Sexual transmission
A: suspected cause
B: May play a role
D: occurs most often in males, hormones are suspected
E: no relation
6. Which of the following makes Behcet’s syndrome different from recurrent aphthous
stomatitis.
a. Skin and eye lesions
b. Triad of locations of lesions: eye, oral, genital
c. Exudate from lesions
d. Mesenchymal proliferations
e. Osteoclastic activity
D: epithelia tissues are involved, however there is also endothelial proliferation that is not
observed in RUS
E: no bone activity in either disease, all are soft tissue involvements
7. Herpangina is caused by
a. Chicken pox virus
b. Coxsackie virus
c. Epstein-Barr virus
d. Varicella
e. Pleurpneumonia like organisms
A: herpes zoster
C: infectious mononucleosis
D: chickenpox
E: assoc with Behcet’s
8. In treatment of fibrous dysplasia, which one of the following would NOT be advised because
it can trigger malignancy?
a. Radiation
b. Surgery
c. Chemotherapy
d. Bone marrow depressants
e. Transplants
9. The MOST conclusive diagnostic approach to a malignant lesion is:
a. Complete excision
b. Radiation therapy
c. Biopsy
d. Chemotherapy
e. Stripping
10. Achlorhydria, inability to absorb vitamin B12, and lack of folic acid are characteristics of
a. Thrombocytopenia
b. Hypervitaminosis
c. Pernicious anemia
d. Hyperkeratosis
e. Herpes
A: decrease #platelets
B: excess of particular vitamin
C: The secretion of intrinsic factor hydrochloric acid does not occure, therefore prevents B12
from being absorbed
D; thickening and the formation of a protective layer of cells over the epithelium
E: virus
11. Bone marrow anoxia occurs in
a. Secondary polycythemia
b. Pernicious anemia
c. Thalassemia
d. Aplastic anemia
e. Thrombocytopenia
B: etiology related to lack of B12 absorption
C: bone marrow shows cellular hyperplasia
D: there is marrow dysfunction
E: there is a decrease in # platelets
12. Which of the following is referred to as “Mediterranean anemia”
a. Acute anemia
b. Thalassemia
c. Primary aplastic anemia
d. Thrombocytopenia
e. AIDS
D: decrease in # platelets
13. Sickle cell anemia is of hereditary origin and occurs primarily in
a. Whites
b. Native Americans
c. Mediterranean ethnic groups
d. African Americans
e. Asian Americans
One in 600 African Americans has SCA