RADIOBIOLOGY Plenary presentations: 3 June 9.00-11.00 Co-Chairmen: C. Mothersill, A. A. Dmitriev Mothersill C., Seymour C. (McMaster University, Hamilton, Ontario, Canada) (30 min) Bystander effects, adaptive responses and hormesis: being on the right part of the stress response curve Dubrova Yu.E. (Department of Genetics, University of Leicester, Leicester, UK) (30 min) Mutation induction in the mouse germline: a genome-wide perspective Surinov B.P., et al. (A. Tsyb Scientific Research center of Radiology of the Hertsen Federal Medical Research Centre of the Ministry of Health of the RF) (30 min) The problem of the influence of low-intensity laser radiation on biologically active substances 1 Dmitriev A. P., Guscha N.I., Dyachenko A. I., Grodzynskyi D. M (Institute of Cell Biology and Genetic Engineering NAS of Ukraine, Kiev, Ukraine) Microevolutionary processes in the 30-km Chernobyl exclusion zone 11.20-13.00 Co-Chairmen: Vorobtsova I.Eu, Dubrova Yu. E. Seymour C., Mothersill C. (McMaster University, Hamilton, Ontario, Canada) (20 min) Relative biological effectiveness of environmentally relevant levels of 226Ra and x-rays on growth and on bystander effects in Fathead Minnows (Pimephales promelas, Rafinesque, 1820) Vorobtsova I., Semenov A. (Fed. St. Inst. Russian Research Center for Radiology and Surgical Technologies, St. Petersburg, Russia) (20 min) Significance of cytogenetic study for estimation of biological effects of low-dose irradiation of people Moskalev A., et al (Inst. of Biology of Komi Science Center of Ural Branch of RAS; Syktyvkar St. Un.; Engelhardt Inst. of Molecular Biology; Moscow Inst. of Physics and Technology) (20 min) Comparison of dose-response transcriptomics and longevity effects of gamma radiation in Drosophila males Hurem S. et al (Centre for Environm. Radioactivity (CERADCoE), Norway; Norwegian Un. of Life Sciences, Vetbio, Campus Oslo, Norway; Norwegian Un. of Life Sciences, Dep. of Environmental Sciences,Campus Ås, Norway) (20 min) Effects of low-dose gamma irradiation during early life stages in the zebrafish model Kuzmina N.S., Lapteva N.Sh., Rubanovich A.B. (N.I. Vavilov Inst. of General Genetics, RAS, Moscow, Russia) (20 min) The epigenetic disturbances in human blood leukocytes in remote period after radiation exposure 1 This report can be changed by Grodzinsky D.M. (Institute of Cell Biology and Genetic Engineering NAS of Ukraine, Kiev, Ukraine) (30 min) Microevolution processes in anthropogenic radionuclide anomalies 3 JUNE Oral presentations: Radiation effects on human 15.00-17.00 Co-Chairmen: L. Baleva, I. Schmidt-Feuerhake I.Schmitz-Feuerhake, S. Pflugbeil (German Society for Radiation Protection, Hannover, Germany) (30 min) Relevance of the Chernobyl research for the evaluation of genetic radiation risks in humans Hadjamberdiev I., Tukhvatshin R. (Toxic Action network Central Asia and Medical Academy, Bishkek, Kyrgyzstan) (30 min) Radioactive areas and health in Tien-Shen Baleva L.S., Sipyaginа A.E., Karahan N. M. (Children's Scientific and Practical Center of Antiradiation Protection Pirogov’s Nat. Research Medical Un., Ministry of Health of RF, Moscow, Russia) (30 min) The dynamics of apoptosis and reparation of genomic DNA indicators in radiation induced diseases formation at children of 1 - 2 generations after the Chernobyl accident Sokolnikov M. (Southern Ural Biophysics Institute, Ozyorsk, RF) (30 min) Radiation epidemiology studies of Mayak workers 17.20 – 18.00 Co-Chairmen: Pflugbeil S., Sokolnikov M. G.F. Aru, Bugay A.N., Parkhomenko A.Yu. (Joint Institute for Nuclear Research, Dubna, Russia) (20 min) Radiation induced changes in dynamics of neural network model for working memory Vorobtsova I. (Federal State Inst. Russian Research Center for Radiology and Surgical Technologies, St. Petersburg, Russia) (20 min) Mix lymphocyte culture from humans of different gender – novel model for study the radiation induced bystander effect 4 JUNE Oral presentations: Radiobiology effects 15.00-17.00 Co-Chairmen: Yu.E. Dubrova, A. Moskalev Moskaleva E. Yu., et al (Natl. Research Center "Kurchatov institute", Moscow, Russia) (30 min) Low dose gamma irradiation stimulates proliferation of stem cells and tumor cells but decreases the size of SP fraction Mikhyeyev A.N. et al (Institute of Cell Biology and Genetic Engineering, NAS of Ukraine, Kiev, Institute of Botany, NAS of Ukraine, Kiev, Ukraine) (30 min) The hierarchy mechanisms of radiogormesis effects on plants Bashlykova L.A. (Institute of Biology Komi SC UrD RAS, Syktyvkar, Russia) (30 min) Transgeneration transfer of response to a chemical mutagen in organisms of animals after different-time ionizing radiation Kadukova E.M. et al. (Institute of Radiobiology, National Academy of Science, Gomel, Belarus) (30 min) Effect of radiation and emotional stress on behaviour of rats in the open field test 17.20 -18.00 Co-Chairmen: Pozolotina V.N., Hurem S. Tryapitsyna G.A., et al (Urals Research Center for Radiation Medicine, Chelyabinsk, Russia; Chelyabinsk St. Un., Chelyabinsk, Russia; Norwegian Un. of Life Sciences (UMB), Center of Excellence in Environmental Radioactivity (CERAD), Ås, Norway; Norwegian Radiation Protection Authority (NRPA), Norway) (20 min) Assessment of adaptive reaction in fish to chronic radiation exposure in the in situ experiments Afanasyeva K.P., Aleksandrov I.D., Aleksandrova M.V. (Joint Institute for Nuclear Research, Dubna, Russia) (20 min) Molecular nature of the heritable gene mutations induced by γ-rays and neutrons in Drosophila germ cells 3 JUNE 13.00-14.00 Poster session: Radiobiology effects Bandarenko M., Kovalenko V. (Dep. of Chemistry, Belarusian St. Pedagogical Un.; Dep. of Organic Chemistry, Belarusian St. Un., Minsk, Belarus) Synthetic analogs of natural phenolic antioxidants and antimutagens from raspberry and ginger Boubriak I.I et al (Inst. of Cell Biology and Genetic Engineering, NAS of Ukraine, Kyiv; Un. of Oxford, Oxford, Great Britain) The efficiency of DNA repair in the priming of sugar and red beet seeds Budarkov V.A. (SRI St. Research Inst. Nat. Research Inst. for Veterinary Virology and Microbiology of Russia (SRI NRIWaMR) of the Russian Academy of Agricultural Science, Volginsky, Russia) Phenotypic manifestations of growth disorders in progeny of hens chronically exposed to 131 I Bychkovskaya I.B., Mylnikov S.V. (St.Petersburg St. Un., St. Petersburg, Russia) Non-mutagenic non-targeted radiation effects as one of the mechanisms of decrease of life span in multicellular organisms Dyukina А.R., et al (Inst. of Theoretical and Experimental Biophysics, RAS, Pushchino, Russia) Induction of genomic instability on three generations of mice irradiated by infrared light Koryakina E.V., V.I. Potetnya (A.Tsyb Scientific Centre of Radiology of the Hertsen Federal Medical Research Centre of the Ministry of Health of RF, Obninsk, Russia) Cytogenetic evidence of HRS/IRS effects in human lymphocytes and Chinese hamster cells following 14.5 MEV neutrons and gamma irradiation Sorokina S.S., et al (Inst. of Theoretical and Experimental Biophysics, RAS, Pushchino, Russia) Combined action of ionizing radiation and food supplement's on the induction of adaptive response and tumor growth on mice in vivo Talalaeva G.V. (Inst. of Plant and Animal Ecology, Ural Branch of RAS, Ekaterinburg, Russia) Gomeorez is the key model transformation of living systems under the influence of low radiation doses Tolstykh E.I. et al. (Urals Research Center for Radiation Medicine, Chelyabinsk, Russia; Dep. of Radiology, Un. of Utah, Salt Lake City, Utah 84112, USA) Local bone marrow exposure: how to interpret the data on stable chromosome aberrations in circulating lymphocytes? Velegzhaninov I.O., et al (Institute of Biology, Komi Science Center of RAS, Syktyvkar, Russia; Canadian Nuclear Laboratories, Chalk River, Ontario, Canada) Qualitative distinctions of dose-effect relationships between different stress responses to ionizing radiation in normal human fibroblasts Yushkova E.A. (Inst. of Biology Komi Science Centre Ural Division RAS, Syktyvkar, Russia) Epigenetic effects mus-mutations in the radiation-induced activation of transposable elements in Drosophila Poster session: Radiation effects on human Batmunkh М., Belov O.V., Lhagva O. (Joint Institute for Nuclear Research, Dubna, Russia) Time-dependent yields of water radiolysis products in CA1 hippocampal neurons exposed to high-energy ions Bekmanov B.O. et al. (Inst. of General Genetics and Cytology, SC MES RK, Almaty, Kazakhstan) Identification of gene variants predisposing to increased radiosensitivity () Belokopytova K.V. , Belov O., et al (Joint Institute for Nuclear Research, Dubna; Zakusov Pharmacology Research Institute, Moscow; RAS Inst. of Higher Nervous Activity and Neurophysiology, Moscow) Dynamics of age-related changes in the exchange of monoamines and their metabolites in rat brain structures after 12C ion irradiation Dorozhkina O.V. et al (Inst. of Biomedical Problems, RAS, Moscow; A.I. Burnazyan Federal Medical and Biophysical Center of FMBA, Moscow; Joint Institute for Nuclear research, Dubna, Russia) Somatic, behavioral and cytogenetic effects after γ-irradiation in low doses Kabirova N.R., Okatenko P.V., Koshurnikova N.A. (Federal state unitary enterprise Southern Urals Biophysics Inst. of Federal Medical Biological Agency, Ozersk, Russia) Mortality rates among the offspring, whose fathers were occupationally exposed to the ionizing radiation sources Makarenko S.A., Zamulaeva I.A (A. Tsyb Scientific Research Centre of Radiology of the Hertsen Federal Medical Research Centre of the Ministry of Health of RF, Obninsk, Russian) Effects of photodynamic therapy on cancer stem cells (CSCs) in vitro Naumov I.A., Sivakova S.P., Moiseenok E.A. (Educational Establishment "Grodno State Medical Un.", Grodno, Belarus) Magistracy interdisciplinary studies curriculum on human security in territories contaminated with radioactive agents Panina M.S., et al (Joint Institute for Nuclear Research, Dubna, Russia; School of Physics and Electronics, Nat. Un. of Mongolia, Ulaanbaatar, Mongolia; Mathematics Dep., Faculty of Science, Cairo Un., Giza, Egypt) Mathematical modeling of the radiation-induced DNA double-strand break repair in mammalian and human cells Pylypchuk E.P, Domina E.A (R.E. Kavetsky Experimental Pathology, Oncology and Radiobiology Inst., NAS of Ukraine, Kiev, Ukraine) Realization cytogenetic damage in irradiated human cells for additional action of comutagen Rusinova G.G. et al (Southern Urals Biophysics Inst. , Ozyorsk, Russia) Dose threshold for detection of mutations in off-springs of Mayak PA workers occupationally exposed to ionizing radiation Severyuhin Y.S., Budennaya N.N., Lyahova K.N. (Joint Institute for Nuclear Research, Dubna, Russia) Pathological and morphological changes of purkinje cells in the cerebellar cortex of rats exposed to ionizing radiation of different types Shishkina E.A. et al. (Urals Research Center for Radiation Medicine, Chelyabinsk; Southern Urals St. Un., Chelyabinsk, Russia) Statistical reconstruction of radiation background doses of rural residents of the Urals based on EPR dosimetry of tooth enamel Sosnina S.F., Sokolnikov M.E., Okatenko P.V. (Southern Urals Biophysics Inst., Ozyorsk, Russia) Hematological malignancies in the offspring of radiation-exposed parents Tolstykh E.I., Degteva M.O., Bugrov N.G. (Urals Research Center for Radiation Medicine, Chelyabinsk, Russia) Body potassium content and radiation doses from 40K to the Urals population (Russia) Voskanyan K.et al.(Joint Institute for Nuclear Research, Dubna; Institute of MedicoBiological Problems of the RAS, Moscow, Russia) Laser devices for reducing the radiation damage of biological objects 4 JUNE Discussion: Low radiation – mechanisms and effects 17.20- 17.40