Cells Part 2—What Are Cells Made of? Cells are mostly made of water. The structure of the water molecule makes it ideal for dissolving other substances. Cells are made of macromolecules—when many small molecules join together. The four types of macromolecules are: 1.__________________________________ 2.__________________________________ 3,__________________________________ 4.__________________________________ Nucleic acids form when long chains of molecules called nucleotides join together. A nucleotide molecule contains a phosphate group, sugar and base Nucleotides are linked together to form chains Nucleic acids are important in cells because they contain genetic information. DNA contains two nucleotide chains wound together in a helical shape Each human chromosome is a single, long DNA molecule compacted by proteins Sub-Cellular Organizational Hierarchy of Life with Examples Cell neuron Organelle nucleus genome chomosome gene Macromolecule DNA Molecule nucleotide Atom nitrogen Sub-atomic particles Protons, neutrons, electrons The macromolecules that are necessary for nearly everything that cells do are proteins. Proteins are long chains of amino acid molecules. A lipid is a large macromolecule that does not dissolve in water. Macromolecules that do not mix with water play an important role as protective barriers in cells. Sugar molecules make up carbohydrates. Carbohydrates store energy and provide structural support. They are also used for communication between cells. Moving Cellular Material Cell Membrane (Transport) Notes Cell Membrane and Cell Wall: ALL cells have a cell membrane made of proteins and lipids • SOME cells have cell membranes and cell walls – ex: plants, fungi and bacteria protein channel Layer 1 Cell Membrane Layer 2 lipid bilayer protein pump • Plant cells have a cell wall made of cellulose – that cellulose is fiber in our diet • Bacteria and fungi also have cell walls, but they do not contain cellulose • Cell membranes and cell walls are porous allowing water, carbon dioxide, oxygen and nutrients to pass through easily Function of the Cell Membrane: • Cell membrane separates the components of a cell from its environment—surrounds the cell • “Gatekeeper” of the cell—regulates the flow of materials into and out of cell—selectively permeable • Cell membrane helps cells maintain homeostasis—stable internal balance Passive Transport A process that does not require energy to move molecules from a HIGH to LOW concentration Diffusion Facilitated Diffusion Osmosis • • • Diffusion is the movement of small particles across a selectively permeable membrane like the cell membrane until equilibrium is reached. These particles move from an area of high concentration to an area of low concentration. outside of cell inside of cell Diffusion HIGH to LOW concentration • Osmosis is the diffusion of water through a selectively permeable membrane like the cell membrane Water diffuses across a membrane from an area of high concentration to an area of low concentration. Semi-permeable membrane is permeable to water, but not to sugar • Facilitated Diffusion is the movement of larger molecules like glucose through the cell membrane – larger molecules must be “helped” Proteins in the cell membrane form channels for large molecules to pass through Proteins that form channels (pores) are called protein channels outside of cell Glucose molecules inside of cell Hypertonic Solutions: contain a high concentration of solute relative to another solution (e.g. the cell's cytoplasm). When a cell is placed in a hypertonic solution, the water diffuses out of the cell, causing the cell to shrivel. Hypotonic Solutions: contain a low concentration of solute relative to another solution (e.g. the cell's cytoplasm). When a cell is placed in a hypotonic solution, the water diffuses into the cell, causing the cell to swell and possibly explode. Isotonic Solutions: contain the same concentration of solute as another solution (e.g. the cell's cytoplasm). When a cell is placed in an isotonic solution, the water diffuses into and out of the cell at the same rate. The fluid that surrounds the body cells is isotonic. Active Transport Active transport is the movement of molecules from LOW to HIGH concentration. Energy is required as molecules must be pumped against the concentration gradient. Proteins that work as pumps are called protein pumps. Ex: Body cells must pump carbon dioxide out into the surrounding blood vessels to be carried to the lungs for exhale. Blood vessels are high in carbon dioxide compared to the cells, so energy is required to move the carbon dioxide across the cell membrane from LOW to HIGH concentration. outside of cell inside of cell Carbon Dioxide molecules ANALOGY Weeee!!! This is gonna be hard work!! high high low • low Endocytosis and Exocytosis is the mechanism by which very large molecules (such as food and wastes) get into and out of the cell Food is moved into the cell by Endocytosis Wastes are moved out of the cell by Exocytosis Ex: White Blood Cells, which are part of the immune system, surround and engulf bacteria by endocytosis. Cells and Energy 1. Cell Respiration All living things need energy to survive. Cellular respiration is a series of chemical reactions that convert energy in food molecules into a usable form of energy called ATP. First step is glycolsis which occurs in the cytoplasm of cells. During glycolsis, glucose (a sugar) is broken into smaller molecules. Step two requires oxygen and occurs in the mitochondria of eukaryotic cells. The smaller molecules made during glycosis are broken down and large amounts of energy, ATP, are produced. Water and carbon dioxide are the two waste products given off. 2. Fermentation Eukaryotic and prokaryotic cells use fermentation to obtain energy from food when oxygen levels are low. Fermentation occurs in the cell’s cytoplasm where glucose is converted into ATP and a waste product called lactic acid. Some types of bacteria and yeasts make ATP during alcohol fermentation. This process produces ethanol and CO2. 3. Photosynthesis Plants and some unicellular organisms obtain energy from light. Light energy, water and CO2 are converted into glucose and oxygen. In plants, light energy is absorbed by pigments such as chlorophyll. The chemical reactions of photosynthesis occur in chloroplasts, the organelles in plant cells that convert light energy into food. Photosynthesis uses CO2 that is released during cellular respiration to make food energy and release oxygen.