Name: _____________________________ Heredity Part 1: Genetics _____________________ o 1800’s Austrian monk, mathematician, and scientist Began working in the garden at his monastery o _______________________ His work led to an understanding of how traits are passed from ____________________ The passing of traits from parents to offspring is called __________________ o Primarily worked with a variety of garden peas Noticed several traits that appeared to follow certain patterns of inheritance o Mendel’s Observations Mendel mated pea plants together until he got plants that were ___________________ Also known as pure-bred o These are organisms that always pass on ____________________ Ex. _______ plant that always has _________ offspring Once he established 2 true-breeding lines for each trait, he mated them together For example, true-breeding yellow seed and true breeding green seeds He noticed that all of the offspring looked like _____ of the parents, but not the other (Ex. All ________, no _________) o Called them ____________ because they got one gene from each parent He then ________________ each of the offspring He noticed that most looked like the parent, but some did not o Generations in crosses: P=_______________________ F1=_______________________ First ones to be crossed Filial=children F2=________________________ Grandchildren o Mendel’s Hypotheses He hypothesized that one of the traits was ____________________ the other He called these traits ________________ Because the other trait was not expressed in the first generation, but reappeared in the second, he hypothesized that the trait was still there, but was being ________________ by the dominant trait. He called these traits ________________ o Example of Mendel’s Experiment-Yellow and green seeds Mendel developed a true-breeding line of plants with ________ seeds and a truebreeding line of plants with ______ seeds He took one __________-seeded plant and one __________-seeded plant and mated them together He then took each of these _________ -seeded plants and self-pollinated them All of the offspring had _________ seeds ______ of the offspring had yellow seeds and ______ had green seeds He concluded that yellow was ________________ and green was _________________ o Results of Mendel’s Experiment Mendel’s experiments continually showed that ____ of the plants showed the dominant trait and ____ showed the recessive trait __:__ ratio o Mendel’s Laws of Inheritance Law of _______________ For any particular trait, the pair of ____________ from each parent separate and only ____ allele passes from each parent to an offspring o Recall that we have ___________ of chromosomes (one set from mom and one set from dad) During meiosis, ___ of these are sorted into each gamete (sex cell) Which one winds up in each is ___________ Law of __________________________ Different pairs of alleles for one trait are passed to offspring _____________ of alleles for other traits o Most traits are NOT linked in any way. You could get your mom’s blue eyes without getting her blonde hair, height, etc. o Mendel’s Principle of Dominance Traits can be ____________ or _____________ Dominant alleles mask, or ______________, recessive alleles Recessive alleles can only be expressed if the offspring receives _____ of the recessive alleles Any time a dominant allele is present, it will be _______________ Symbols for alleles o Dominant alleles are represented by _________________________ Example: A, B, C, D o Recessive alleles are represented by _________________________ Example: a, b, c, d o The gene is represented by _________________ letter, and dominant and recessive alleles of the gene are shown by whether they are _______________________ o You Try It: Indicate whether the following are dominant or recessive: T- d- P- E- e- Homozygous vs Heterozygous o Recall that organisms get 2 alleles-1 from each parent o _______________-2 of the same alleles for a trait “Homo” means _________ Example: ___ or ____ Can be homozygous dominant (_____) or homozygous recessive (____) o _______________-2 different alleles for a trait “Hetero” means _____________ Example: ____ or tT Note: The latter is rarely used, but will sometimes be the result in a Punnett Square o You Try It: Indicate whether the following are heterozygous, homozygous dominant, or homozygous recessive TT- Tt- tT- tt- Punnett Squares o Tool to __________________ of a cross (mating) o Often a 2x2 grid Can be larger if including more traits o Couple of different types ____________ cross (one trait) ____________ cross (2 traits) Trihybrid cross (3 traits)-gets too time consuming for this class And more that are too complicated to be done by hand and are instead done using computers Punnett Squares Show Probability o Not actuality! o Coin flip If you flip a coin, what is the chance that it comes up heads? _________ If you flip it again, what is the chance that it comes up heads a second time? _____ o If there is a 1 in 4 chance that offspring will have blue eyes, and you have 3 children with brown eyes, will the 4th one for certain have blue eyes? __________ Using Punnett Squares Draw example one here: o Begin by drawing a 2x2 grid o Place one parent’s alleles on top o Place the other parents alleles on the left side o Bring ones on the top down o Bring ones on the left across Practice Problem o A pea plant with genotype Rr is mated with a pea plant with genotype rr. What genotypes could the offspring have? Genotype and Phenotype o Genotype- The genes (__________) that an organism has Geno=gene Example: Aa, BB, cc o Phenotype- The expression (_______________) of the genotype Ph-Physical Example: Green eyes, brown hair, tall o You Try It: Indicate whether the following are genotypes or phenotypes. Aa- Blue eyes- Rolling tongue- TT- Principles of heredity o Traits are controlled by ___________ (different versions of a gene) on a chromosome o An allele can be ________________ or _______________________ o When a pair of chromosomes separate during meiosis, the different alleles for a trait move into different _____________________ Dihybrid Crosses o Deals with 2 traits Looking at 2 genes, so ____ possible alleles o Little bit more complicated Punnett Square will be ________ o ____ possible combinations o _______________________ is still followed F1 generation will still show ____________ phenotype F2 generation will have a ration of ___________________ o How to set up Punnett Square One allele from each trait will join with one for the other trait, and will give 4 allele combinations Ex: AaBb ___________________________ Do for both parents Draw a 4x4 grid Place alleles for one parent on top, the other on the side Solve like other Punnett Squares, only make sure to bring both alleles down and across o Example Dihybrid Cross If you cross a pea plant with genotype Rryy and one with rrYY, what are the possible genotypes of the offspring? 1st plant allele combinations: _______________________________________ 2nd plant allele combinations: _______________________________________ Draw a 4x4 grid and place alleles: