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Ashok N. Babu

Interests

Education

Awards received

Publications

Adult cardiac surgery to include coronary and valve operations, mechanical circulatory support, extracorporeal membrane oxygenation (ECMO), adult congenital heart disease, redo surgery, and heart and lung transplantation.

1995-1998 Northwestern University Evanston, IL

Biomedical Engineering / Honors Program in Medical Education

Suma Cum Laude

1998-2002

Medical School

Northwestern University Medical School Chicago, IL

2002-Present University of Colorado

General Surgical Residency

Denver, CO

Denver, CO 2005-2007 University of Colorado

2 year Research Fellowship

2007-2009 University of Colorado

General Surgical Residency

Denver, CO

2009-2012 University of Colorado

Thoracic Surgery Residency

Denver, CO

Jan and Feb, 2011 Duke University Durham, NC

Fellowship in mechanical circulatory support, heart / lung transplantation

J. Cuthbert Owens Award for Excellence in Teaching and Patient Care-2005

Ben Eiseman Basic Sciences Research Award-2007

Golden Apple Teaching Award-2009

Babu AN, Murakawa T; Thurman JM, Miller EJ, Henson PM, Zamora MR,

Voelkel NF, Nicolls MR. Microvascular destruction identifies murine allografts that cannot be rescued from airway fibrosis. Journal of Clinical Investigation.

2007 Dec 3;117(12):3774-3785.

Babu AN, Damle SS, Moore EE, Ao L, Song Y, Johnson JL, Weyant M,

Banerjee A, Meng X, Fullerton DA. Hemoglobin-Based Oxygen Carrier

Induces Hepatic Heme Oxygenase 1 Expression In Kupffer Cells. Surgery . 2007

Aug;142(2):289-94.

Babu AN, Meng X,Cleveland JC, Banerjee A, Fullerton DA, Weyant M.

Secretory Phospholipase A2 is Required to Produce Histologic Changes

Associated with Gastroduodenal Reflux in a Murine Model. Journal of

Thoracic and Cardiovascular Surgery . 2008 Jun;136(6):1220-7.

Babu AN, Meng X, Zou N, Yang X, Wang M, Song Y, Cleveland JC, Weyant

M, Banerjee A, Fullerton DA. Lipopolysaccharide Stimulation of Human Aortic

Valve Interstitial Cells Activates Inflammation and Osteogenesis. Annals of

Thoracic Surgery . 2008 July;86(1):71-6.

Babu AN, Meng X, Cleveland JC, Banerjee A, Fullerton DA, Weyant M. The

Secretory Phospholipase A

2

Gene is required for gastroesophageal reflux-related changes in murine esophagus. Journal of Gastrointestinal Surgery. 2009

Dec;13(12):2212-8.

Babu AN, Nicolls MR. Critical Pathways Leading to Obliterative Bronchiolitis in Lung Allografts. Current Opinion in Organ Transplantation . 11(5):483-489,

October 2006.

Meng X, Ao L, Song Y, Babu AN, Yang X, Wang M, Weyant MJ, Dinarello

CL, Cleveland JC, Fullerton DA. Expression of Functional Toll-like Receptors

2 and 4 in Human Aortic Valve Interstitial cells: Potential Roles in Aortic Valve

Inflammation and Stenosis. Am J Physiol Cell Physiol . 2008 Jan;294(1):C29-35.

Babu AN, Nicolls MR. The matrix comes to lung transplantation.

Transplantation . 2007 Mar 27;83(6):683-4.

Damle SS, Moore EE, Babu AN, Meng X, Fullerton DA, Banerjee A.

Hemoglobin-based oxygen carrier induces heme oxygenase-1 in the heart and lung but not brain. Journal of the American College of Surgeons . 2009 Apr;

208(4):592-8.

Mauchley D, Meng X, Babu A, Gamboni-Robertson F, Yang X, Banerjee A,

Fullerton DA, Weyant MJ. Gastroduodenal reflux induces group IIa secretory phospholipase A(2) expression and activity in murine esophagus. Diseases of the Esophagus . 2010 Jan 15. (Epub ahead of print)

Mauchley D, Meng X, Johnson T, Teitelbaum J, Babu A, Fullerton DA, Weyant

MJ. Heat shock protein 27: induction by gastroduodenal reflux in vivo and augmentation of human esophageal mucosal cell growth in vitro.

J Thorac Cardiovasc Surg . 2010 Apr;139(4):1019-25.

Babu AN, Mitchell JD. Muscle flaps in thoracic surgery. Operative Techniques in Thoracic and Cardiovascular Surgery . 2010.

Macht M, Mitchell JD, Cool C, Lynch DA, Babu A, Schwarz MI. A 31-year-old woman with hemoptysis and an intrathoracic mass. Chest. 2010 Jul;138(1):213-

9.

Damle SS, Moore EE, Babu AN, Meng X, Fullerton DA, Banerjee A.

Hemoglobin-based oxygen carrier induces heme oxygenase-1 in the heart and lung but not brain. J Am Coll Surg. 2009 Apr;208(4):592-8.

Babu AN, Nicolls MR. The matrix comes to lung transplantation.

Transplantation. 2007 Mar 27;83(6):683-4. eat shock protein

Gastroduodena

Presentations Babu AN, Murakawa T, Zamora M, Grover F, Kerklo M, Nicolls MR.

Prolonged Alloimmune Injury Leads to Irreversible Fibrosis in Murine

Orthotopic Tracheal Transplant. Society of University Surgeons Annual

Meeting, San Diego CA, 2006.

Babu, AN; Murakawa, T; Kerklo, M; Tamosiuniene, R; Zamora, M.; Gill, RG;

Grover, F; Miller, EJ; Nicolls, MR. VEGF-Independent Angiogenesis Identifies

Non-Reversible Airway Injury Culminating in Fibrosis.” World Transplant

Congress 2006. American Journal of Transplantation 6 (s2), 473.

Babu AN, Murakawa T, Zamora M, Grover F, Kerklo M, Nicolls MR. A new model of airway transplantation to evaluate early inflammatory events, fibroproliferation and epithelial mesenchymal transition (EMT). Thomas Petty

Annual Aspen Lung Conference. Aspen CO, 2006

Babu, AN; Damle, SD; Robinson, TN. Radiofrequency Tissue Fusion – Two

Seals are Equivalent to One. Society of Gastrointestinal and Endoscopic

Surgeons Annual Meeting 2006.

Babu, AN; Murakawa, T; Zamora, MR; Grover, F; Fullerton, DA; McIntyre, R;

Moore, EE; Nicolls, MR. Anti-Inflammatory Pathways Potently Upregulated in

Model of Irreversible Alloimmune Airway Fibrosis. Shock Society Meeting,

Broomfield CO, 2006.

Babu, AN; Damle, S; Moore, EE; Ao, L; Song, Y; Johnson, JL; Banerjee, A;

Meng, X; Fullerton, DA. Hemoglobin-Based Oxygen Carrier Induces Hepatic

Heme Oxygenase 1 Expression In Kupffer Cells. Society of University

Surgeons Annual Meeting 2007, Phoenix, AZ.

Babu, AN; Meng, X; Banerjee, A; Wang, M; Weyant, MJ; Cleveland, JC;

Fullerton, DA. Toll-like Receptor 4 on Human Aortic Valves Mediates

Mechanisms of Aortic Stenosis. The Society of Thoracic Surgeons Annual

Meeting, San Diego, CA, 2007.

Babu, AN; Murakawa, T; Henson, P; Zamora, M.; Voelkel, NF.; Nicolls, MR.

Functional Microcirculation is Lost in Airway Fibrosis. Thomas Petty Annual

Aspen Lung Conference. Aspen CO, 2007

Babu AN, Meng X, Cleveland JC, Banerjee A, Fullerton DA, Weyant M.

Secretory Phospholipase A2 is Required to Produce Histologic Changes

Associated with Gastroduodenal Reflux in a Murine Model. Western Thoracic

Surgical Association Annual Meeting 2007.

Babu, AN; Damle, S; Moore, EE; Ao, L; Song, Y; Johnson, JL; Weyant, ML;

Banerjee, A; Meng, X; Fullerton, DA. Therapeutic Induction of Heme-

Oxygenase-1 in the Lung Using a Hemoglobin-Based Oxygen Carrier. Surgical

Forum—ACS Annual Meeting 2007.

Babu AN, Meng X, Cleveland JC, Banerjee A, Fullerton DA, Weyant M.

Secretory Phospholipase A

2

Group IIa Mediates Gastroduodenal Reflux-

Induced Mucosal Hyperplasia. The Society of Thoracic Surgeons Annual

Meeting, 2008.

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