Programme Schedule: “Programmed Cell Death in Biology and Medicine” DAY 1 (June 21st, 2012) 9:30 – 10:00 Registration MORNING SESSION Chair: Vsevolod A. Tkachuk (Faculty of Medicine, Moscow State University, Moscow, Russia) 10:00 - 10:30 10:30 – 11:00 Welcome address Guido Kroemer (Institut Gustave Roussy, France) Immunogenic cell death in cancer therapy 11:00 - 11:30 Vladimir Skulachev (Faculty of Bioengineering and Bioinformatics, Moscow State University, Russia) Rechargeable mitochondria-targeted antioxidants SkQs as antiapoptotic and antiphenoptotic drugs 11:30 – 12:00 Gerry Melino (University of Rome ‘Tor Vergata’, Italy) Loss of p63 and its miR205 target results in enhanced cell migration and metastasis in prostate cancer 12:00 - 12:30 Coffee-break AFTERNOON SESSION Chair: Sten Orrenius (Karolinska Institutet, Stockholm, Sweden) 12:30 – 13:00 13:00 - 13:30 13:30 – 14:00 14:00 – 15:30 15:30 – 16:00 16:00 – 16:30 16:30 – 17:00 17:00 – 17:30 Sergey Nedospasov (Engelhardt Institute of Molecular Biology of the RAS, Russia) Tumor Necrosis Factor: distinct functions specified by distinct cellular sources Alexander Ishov (University of Florida, USA) Daxx and USP7: novel regulators of genomic stability, mitosis and taxanes sensitivity Inna Lavrik (German Cancer Research Center, Moscow State University Germany/Russia) Towards understanding the regulation of CD95 signaling by quantitative biology Lunch / Poster Session Peter Bozhkov (Swedish University of Agricultural Sciences and Linnean Center for Plant Biology, Sweden) Death without apoptosis: How do plant cells die? Zahra Zakeri (Queens College Graduate Center of the City University of New York, USA) Manipulation of cellular components by RNA virus Andrey B. Vartapetian ( Belozersky Institute of Physico-Chemical Biology, Moscow State University, Moscow) Phytaspases: A plant alternative to animal caspases (Selected Abstract) Martin Bushell (University of Leicester, UK) Translational repression is the primary and critical step for microRNA mediated regulation DAY 2 (June 22nd, 2012) MORNING SESSION Chair: Richard A. Lockshin (Department of Biological Sciences, St. John's University, New York, USA) 10:00 – 10:30 10:30 – 11:00 11:00 - 11:30 11:30 – 11:50 11:50 – 12:10 12:10 - 12:45 Mauro Piacentini (National Institute for Infectious Diseases "Lazzaro Spallanzani", Italy) Type2 Transglutaminase is involved in the autophagy-dependent clearance of ubiquitinated proteins Vladimir Gogvadze (Karolinska Institutet, Moscow State University, Sweden/Russia) Targeting mitochondria with α-tocopheryl succinate stimulates neuroblastoma cell death irrespective of MycN expression Hans-Uwe Simon (University of Bern, Switzerland) Programmed cell death pathways in neutrophils Ludmila B Buravkova (Institute of Biomedical Problems RAS, Moscow, Russia) Photodynamic therapy-induced apoptosis in vascular wall-associated cells in vitro (Selected Abstract) Alexander P. Savitsky (A.N. Bach Institute of Biochemistry, RAS, Moscow, Russia) Visualization of caspase-3 activity. Computer simulations of substrate structure and life-time imaging of live cells (Selected Abstract) Coffee-break AFTERNOON SESSION 12:45 - 13:15 Boris Zhivotovsky (Karolinska Institutet, Moscow State University, Sweden/Russia) A calcium-calmodulin-dependent pathway in regulation of cell death 13:15 – 13:45 13:45 – 14:15 14:15 - 14:30 Marie-Lise Gougeon (Institut Pasteur, France) Innate sensing of viral infection and programmed cell death Peter Vandenabeele (Ghent University, Belgium) Molecular mechanisms of necroptosis, a regulated form of cellular explosion Closing remarks