Baby Doe vs. The Prenatal Clinic: When Cell Division Goes Awry
1. What is Down Syndrome?
A. A condition caused when the mother drinks alcohol while pregnant.
B. A form of childhood cancer.
C. A birth defect resulting in a split upper lip and speech problems.
D. A condition caused when the baby has too many copies of a chromosome.
2. The diploid chromosome number in standard laboratory mice (genus Mus) is 40. What is n for this
organism?
A. 80
B. 40
C. 20
D. 10
3. If you investigated cells from a lab mouse with 40 chromosomes you would find a total number of ____
sister chromatids first after the ___ stage.
A. 10: G1
B. 20: G2
C. 40: M
D. 80: S
For questions #4-5, use the following pictures:
A.
D.
E.
B.
C.
F.
G.
H.
4. The cell (shown below) shows a diploid organism with two chromosomes (2n=2). The pictures above
show some of the steps this cell may go through during mitosis or meiosis. Place the appropriate steps
in order for a cell through mitosis. (Note: you may use just some or all of the steps).
Cell:
A.
B.
C.
D.
HDAC
ABCDEF
EGDC
EBHFA
5. The cell (shown below) shows a diploid organism with two chromosomes (2n=2). The pictures above
show some of the steps this cell may go through during mitosis or meiosis. Place the appropriate steps
in order for a cell through meiosis. (Note: you may use just some or all of the steps).
A. HDAC
B. ABCDEF
C. EGDC
D. EBHFA
6. The different copies of chromosome 21 in John and Jane are shown below.
Parent 1:
A.
Parent 2:
Which of the following is a normal gamete that might be produced by either John or Jane?
B.
C.
D.
E.
7. How can a cell end up with an incorrect number of chromosomes?
A. The chromosomes do not separate correctly during mitosis or meiosis.
B. The chromosomes are copied incorrectly during mitosis or meiosis.
C. Cells divide too many times.
D. The chromosomes become damaged when they are being copied.
E. Cells eliminate chromosomes they don’t need. Sometimes this doesn’t happen.
8. The different copies of chromosome 21 for John, Jane, and their baby are shown below. When and
where did the mistake occur?
A.
B.
C.
D.
E.
Meiosis I of parent #1
Meiosis I of parent #2
Meiosis II of parent #1
Meiosis II of parent #2
Either Meiosis I or II of parent #1
9. If you were on the jury for the malpractice trial of the doctor, what would you decide?
A. The doctor must have done something wrong to cause cell division to have malfunctioned.
B. The doctor could not have done anything to cause the problem.
C. It is impossible to tell if the doctor could be at fault.
10. When would be the best time to isolate chromosomes for a karyotype?
A. G1
B. S-phase
C. G2
D. Prophase
E. Metaphase
F. Anaphase
G. Telophase
11. Does this person have down syndrome?
A. Yes
B. No
12. Is the clinic liable for not testing for Down syndrome?
A. Yes, the clinic should have tested the baby for Down syndrome.
B. It is liable only if the clinic failed to follow suggested guidelines for when to perform the test.
C. Yes, it doesn’t matter if the clinic was at fault or not.
D. No, the clinic should not be held at fault for something beyond its control.