Effective date of implementation: Subject code: Course number: Course title: Short title: Grading basis: Consent required: Credit weight: Fall 2010 PHARM 601 Graduate Seminar Graduate Seminar Pass/fail None 0.25 Course description: This is a required course for all students enrolled in graduate studies in the School of Pharmacy. It requires the student to present their thesis research proposal to a public audience and to discuss, in a closed manner, the proposal with their advisory committee. From time to time, a guest speaker may be brought in to discuss a particular scientific topic or presentation skill. Meet type(s): seminar Primary meet type: seminar Requisites: none Antirequisites: none Corequisites: none Special topics course: no Cross-listed: no Sections combined/heldwith: no Rationale: New course for recently approved pharmacy masters program 1 Effective date of implementation: Subject code: Course number: Course title: Short title: Grading basis: Consent required: Credit weight: Fall 2010 PHARM 602 Grant writing in the sciences Grant writing in the sciences Numeric None 0.5 Course description: The course is designed to teach the student how to critically review the literature, ask the right scientific questions, generate hypotheses, and write a professional curriculum vita and a fundable grant proposal. The course will include lectures from the instructor and guest speakers, small group discussion, student presentations and a final written grant proposal. Meet type(s): lecture Primary meet type: lecture Requisites: none Antirequisites: none Corequisites: none Special topics course: no Cross-listed: no Sections combined/heldwith: no Rationale: New course for recently approved pharmacy masters program 2 Effective date of implementation: Subject code: Course number: Course title: Short title: Grading basis: Consent required: Credit weight: Fall 2010 PHARM 603 Selected topics in Medicinal Chemistry Topics in Medicinal Chemistry Numeric None 0.5 Course description: This course provides an introduction to basic principles in medicinal chemistry such as physicochemical properties, drug design and pharmacological actions. A brief overview of the theory and application of computer aided drug design principles will provide a basic understanding of the “in silico” drug design concepts. The student will develop an understanding toward the concepts of peptide/peptidomimetic design as therapeutic agents. A series of case studies on clinical drugs will be presented with major emphasis on their design, synthesis, reaction mechanisms and structure‐activity relationship studies. A section of the course will address the pathophysiology and pharmacology of diseases affecting the central nervous system. In addition, learning activities and assignments include a term paper submission and in class presentation of current topics in medicinal chemistry. Meet type(s): lecture Primary meet type: lecture Requisites: none Antirequisites: none Corequisites: none Special topics course: no Cross-listed: no Sections combined/heldwith: no Rationale: New course for recently approved pharmacy masters program 3 Effective date of implementation: Subject code: Course number: Course title: Short title: Grading basis: Consent required: Credit weight: Fall 2010 PHARM 604 Gene Therapy Gene Therapy Numeric None 0.5 Course description: Gene therapy offers extraordinary potential to treat both inherited and acquired diseases by using the body’s own machinery to produce a therapeutic compound or protein, or up‐regulate/down‐regulate specific cellular processes. This course will examine the various extra‐ and intra‐cellular barriers to DNA transfection, and the common vectors used in gene therapy. Various routes of administration, such as injected, inhaled, and transdermal will be discussed in terms of their challenges, and the successes of recent formulations described in the literature. Meet type(s): lecture Primary meet type: lecture Requisites: none Antirequisites: none Corequisites: none Special topics course: no Cross-listed: no Sections combined/heldwith: no Rationale: New course for recently approved pharmacy masters program 4 Effective date of implementation: Subject code: Course number: Course title: Short title: Grading basis: Consent required: Credit weight: Fall 2010 PHARM 605 Physical Chemistry and Application of Surfactants Physical Chemistry and Surfactants Numeric None 0.5 Course description: Surface active compounds, more commonly known as surfactants are found in nearly every aspect of day to day life, including motor oils, pharmaceuticals, cosmetics, detergents, and paints and inks to name a few. This course will introduce the student to the structures of classical and emerging classes of surfactants and their fundamental properties that make these systems so useful. The self‐assembly of these compounds into micelles will be discussed in detail using both thermodynamic and kinetic models and modern methods of characterizing these systems will be examined. The application of surfactants in a variety of industries will be introduced. The capstone activity of this course will entail a critical analysis of a relevant recent journal article, and presentation to the class Meet type(s): lecture Primary meet type: lecture Requisites: none Antirequisites: none Corequisites: none Special topics course: no Cross-listed: no Sections combined/heldwith: no Rationale: New course for recently approved pharmacy masters program 5 Effective date of implementation: Subject code: Course number: Course title: Short title: Grading basis: Consent required: Credit weight: Fall 2010 PHARM 606 Neuroscience in the 21st Century Neuroscience Numeric None 0.5 Course description: This course will intensively examine medical and technological advances in neuroscience. Students will first develop a deep understanding of the structure and function of the central nervous system, neuronal cell biology and physiology, and neurotransmission. We will explore selected CNS disease states and identify mechanisms of neuropathology by biological, environemental, and iatrogenic causes. Advances in technology and nanotechnology is and will continue to transform the treatment of diseases of the nervous system and these issues will be explored by expert guest lecturers. Meet type(s): lecture Primary meet type: lecture Requisites: none Antirequisites: none Corequisites: none Special topics course: no Cross-listed: no Sections combined/heldwith: no Rationale: New course for recently approved pharmacy masters program 6 Effective date of implementation: Subject code: Course number: Course title: Short title: Grading basis: Consent required: Credit weight: Fall 2010 PHARM 607 Advanced Pharmaceutical Analysis Advanced Pharmaceutical Analysis Numeric None 0.5 Course description: This course provides an introduction to modern spectroscopic methods with emphasis on pharmaceutical analysis. First few lectures will cover the theory and application of UV‐Vis and IR spectroscopy. A review of NMR spectroscopy will focus on commonly used techniques such as 1H NMR and 13C NMR and their application. The student will get a practical experience in spectroscopic methods for structural elucidation by using UV‐Vis, IR and NMR spectrometers. In addition, a section will address the theory and application of mass spectrometry. Examples of drug molecules/pharmaceuticals and their spectroscopic characteristics will be discussed. In addition, learning activities and assignments include problem sets and structural elucidation of an unknown organic molecule Meet type(s): lecture Primary meet type: lecture Requisites: none Antirequisites: none Corequisites: none Special topics course: no Cross-listed: no Sections combined/heldwith: no Rationale: New course for recently approved pharmacy masters program 7