PANAGIOTIS G. HALVATSIOTIS Date and Place of birth : May 20 1960, Serres-Greece Citizenship: Greek Address: 13 Ploutarchou street, Athens GR - 106 75 Tel: +30-210-5831149 Email: pahalv@gmail.com EDUCATION 1978: Apolytirion of Lyceum - High School Evangeliki Model School, Athens Greece 1986: Ptychion Athens University Medical School, Greece 1999: Fellowship Certificate Mayo Postgraduate School of Medicine, MN, USA DIPLOMAS 1992: Doctoral Thesis University of Athens, Medical School, Greece 1997: State Recognition as Internist Hellenic Ministry of Health and Welfare 2000: State Recognition as Diabetologist Hellenic Ministry of Health and Welfare MEDICAL POSITIONS 1978-1986: Medical Student in Athens University Medical School, Greece 1983-1984: Scholar, Medical Student in Mount Sinai School of Medicine State University of New York, New York, USA 1986-1989: Postgraduate Scholar of “A. Onassis” Foundation 2nd Department of Internal Medicine-Propaedeutic of Athens University (Chairman Professor S.A.Raptis, MD), Greece 1989-1990: Mandatory Hellenic Army Service as Lieutenant Doctor in the 2nd Batallion of Paratroopers 1990-1991: Mandatory Service as a State rural Doctor in Proussos Village, Evrytania Prefecture, Greece 1991-1996: Resident in Internal Medicine 2nd Department of Internal Medicine-Propaedeutic of Athens University (Chairman Professor S.A.Raptis, MD), Greece 1996-1997: Associate in Hellenic National Diabetes Center Athens, Greece 1997-1999: Research Fellow in Endocrinology Mayo Clinic MN, USA 1999-2002: Associate in Athens University, Greece 2002-2006: Elected in the Faculty of Athens Medical School as Lecturer, “Attikon” Univ.Hosp. 2006-onwards: Elected in the Faculty of Athens Medical School as Assistant Professor, “Attikon” Univ.Hosp. MEMBERSHIPS - Hellenic Vascular Association Hellenic Diabetologic Association Hellenic Transplantation Society Hellenic Society of Internal Medicine “A.Onassis” Foundation Scholar Association International Hippokrates Foundation Hellenic Society of Metabolic Syndrome Hellenic Society of Obesity Hellenic Society the “Pancreas” Hellenic Society of Clinical Nutrition and Metabolism (Chairman) Hellenic Society of Internal Medicine (Board Member for 3 consecutive terms) European Association for the Study of Diabetes American Diabetes Association International Diabetes Federation (Life member) Mayo Alumni Society The Plummer Society of Internal Medicine European Society of Internal Medicine AWARDS – SCHOLARSHIPS - Scholarship of the Mount Sinai School of Medicine, New York, NY, USA as a visiting medical student Scholarship of the “A.Onassis” Foundation granting the Doctoral Thesis European Grant for research fellowship in Mayo Clinic, Rochester, MN, USA 1st Research Award in the 13th Annual Congress of the Hellenic Society of Internal Medicine, Athens 2007 Finalist (6 best abstracts) in the 9th World Congress of Insulin Resistance, Los Angeles 2011 CHAIRMANSHPS 10 International and 16 National Meetings LECTURER 14 International and 117 National Meetings EDITOR – REVIEWER -Member of the International Peer Review Panel in Metabolism, The Danish Ministry for Science, Technology and Innovation, 2011 - Reviewer in 2 medical journals -Guest Editor, Hormone & Metab Res 1995 -Co-Editor, Experimental and Clin Endocrinol and Diabetes, 2001 -Co-Editor for the Greek version of the European Manual of the Int. Medicine, 2005 -Reviewer of the National Institute for Postgraduate Studies -Abstract reviewer in 5 National Congresses CLINICAL EXPERIENCE -In Internal Medicine -In Diabetology INTERNATIONAL & NATIONAL AFFILIATIONS -Department of Endocrinology, Mayo Clinic, Rochester MN, USA -Department of Electronic Engineers, National Polytechnic School -European Project in the FP7 HEALTH 2012-2.4.3-1 MEMBER OF ORGANIZING COMMITTEES: 7 International & 8 National Congresses (General Secretary-Treasurer) MEMBER OF BOARDS (elected) -Ethics Committee of the General University Hospital “Attikon” -Board Member as the representative of all doctors in the General University Hospital “Attikon” TEACHING DUTIES - 4th year, 6th year and Dental School medical students in the subject of Internal Medicine, Clinical Endocrinology and Clinical Pharmacology Residents in Internal Medicine, ICU, Anesthesiology, Surgery, Obstetrics and Cardiology in Diabetology Postgraduate students in Diabetology, Metabolism and Endocrinology PUBLICATIONS/PARTICIPATION IN MEETINGS -9Articles in peer reviewed journals -1 Chapter in an Endocrinology Textbook -2 Chapters in an Internal Medicine Textbook -7 Chapters in Proceedings -48 abstracts in International Scientific Meetings (26 as 1st author) -207 citations (self citations not included) ABSTRACTS 1. Raptis S., G. Dimitriadis, A.Ε. Raptis, A. Mitrakou, E. Hatziagelaki, P. Halvatsiotis : Effects of a new Long-Acting α-Glucosidase Inhibitor (BAY-1248) on Glycaemic Control in Insulin-Dependent Diabetes Mellitus. 20th Congress of EASD, London - U.K., 12-15 September 1984. Diabetologia, 27, 2, 323A, 1984 2. Raptis S., G. Dimitriadis, A.Ε. Raptis, A. Mitrakou, E.Hatziagelaki, P.Halvatsiotis: Evaluation of two new glucosidase inhibitors in the treatment of insulin-dependent diabetics,using the Artificial Endocrine Pancreas. First International Workshop on Glucosidase Inhibitors BAYm 1099 and BAYo 1248., Duesseldorf - Germany, Steigenberger Parkhotel, November 29 - December 1 1984 3. Raptis S., D. Hadjidakis, G. Dimitriadis, A.Ε. Raptis, A. Mitrakou, E. Hatziagelaki, P. Halvatsiotis, E. Diamantopoulos: Artificial Endocrine Pancreas (AEP) applications in estimating insulin doses and monitoring IDDM patients on open loop systems or intensified insulin therapy.,4rd Workshop of the EASD Study Group on Artificial Insulin Delivery Systems and Pancreas and Islet Transplantation.,Abstract Book p.68-69, Igls - Austria, 3 -5 February 1985 4. Raptis S., E. Hatziagelaki, G. Dimitriadis, A. Mitrakou, A.Ε. Raptis, P. Halvatsiotis, S. Ladas, I. Hillebrand : Der Einfluss von zwei neuen αGlukosidase-Hemmern auf den Blutzuckertagesverlauf und den Insulinbedarf bei Diabetikern, gemessen mit Hilfe des Kuenstlichen Endokrinen Pankreas. 20 te Jahrestagung der Deutschen Diabetes Gesellschaft, Mainz - Germany, 16-18 May 1985., Actuelle Endokrinologie und Stoffwechsel 2, 6, 103, 1985 5. A.Mitrakou, C.H.Bartsokas, D.Hadjidakis, D.Papachristou, P.Halvatsiotis, A.Souvatzoglou, S.Raptis: The reclassification of GH-deficiency by GRF application., 28emes Journee Internationales Henri-Pierre Klotz d’Endocrinologie Clinique (Paris France) 6 June 1985 6. Raptis S., D. Hadjidakis, G. Dimitriadis, A.Ε. Raptis, A. Mitrakou, E. Hatziagelaki, P. Halvatsiotis, E. Diamantopoulos : Artificial Endocrine Pancreas (AEP), application in estimating insulin doses and in monitoring IDDM patients on open loop systems or intensified insulin therapy., XII Congress of the International Diabetes Federation, Madrid - Spain, 23-28 September 1985. Diabetes Research and Clinical Practice, Suppl.1, 462, 1985 7. Dimitriadis G., S. Raptis, A.Ε. Raptis, A. Mitrakou, E. Hatziagelaki, P. Halvatsiotis, S. Ladas, I. Hillebrand : Evaluation of two new α-glucosidase inhibitors (BAY-1248 and BAY-1099) in the treatment of patients with insulindependent diabetes mellitus using the Biostator. XII Congress of the International Diabetes Federation, Madrid - Spain, 23-28 September 1985., Diabetes Research and Clinical Practice, Suppl.1, 137, 1985 8. Hatziagelaki E., G. Dimitriadis, P. Halvatsiotis, A.Ε. Raptis, E. Katoulis, M. Mitrakou, V. Komesidou, I. Hillebrand, S.Raptis: Therapeutischer Effekt von zwei neuen α-Glukosidasehemmern bei insulinpflichtigen Diabetikern nach vierwoechiger applikation. , 21te Jahrestagung der Deutschen DiabetesGesellschaft, Paderborn - Germany, Mai, 1986. 9. Dimitriadis G., S. Raptis, E. Hatziagelaki, A.Ε. Raptis, A. Mitrakou, P. Halvatsiotis, S. Ladas, V. Komesidou, E. Katoulis, I. Hillebrand: Improvement of glucemic control after prolonged administration of two new α-Glucosidase inhibitors in patients with Insulin Dependent Diabetes. 46th Annual Meeting of American Diabetes Association, 21-24 June, Anaheim California - USA, 1986. , Diabetes, 35, Suppl. 1, 67A, 1986 10. Hatziagelaki E., G. Dimitriadis, P. Halvatsiotis, A.Ε. Raptis, E. Katoulis, M. Mitrakou, V. Komesidou, I. Hillebrand, S.Raptis: Therapeutischer Effekt von zwei neuen α-Glukosidasehemmern bei insulinpflichtigen Diabetikern nach vierwoechiger applikation. , 22te Jahrestagung der Deutschen DiabetesGesellschaft, Aachen - Germany, 28-30 Mai, 1987., Aktuelle Endokrinologie und Stoffwechsel 2, 8 ,82, 1987 11. D.Hadjidakis, P.G.Halvatsiotis, Y.Ioannou, S.Raptis: The effects of somatostatin analogue SMS 201-995 on carbohydrate homeostasis of type I diabetics as assessed by the Artificial Endocrine Pancreas (AEP) 47th Annual Meeting of American Diabetes Association, 7-9 June, Indianapolis IN - USA, 1987. , Diabetes, 36, Suppl. 1, 124A, 1987 12. S.Raptis, A.Mitrakou, P.Halvatsiotis, E.Hatziaggelaki: Normal glucose tolerance test after 3 years of cyclosporine treatment in nondiabetic patients. 49 th Annual Meeting of American Diabetes Association, 3-6 June, Detroit MI - USA, 1989. , Diabetes, 38, Suppl. 1, 155A, 1989 13. Mitrakou A, Hatziangelaki E., Raptis G., Halvatsiotis P., S.A.Raptis: Normal glucose tolerance test after 3 years of cyclosporine treatment in nondiabetic patients, Sir Roy’s Calne’s European Forum on Immunosuppression in Organ Transplantation, 6-8 November 1990, Athens, Greece 14. Halvatsiotis P., K.Delli, S.Droufakou, A.Yalouris, S.A.Raptis: Association of time and storage in evaluation of glycosylated haemoglobin using High Performance Liquid Chromatography., 15th International Diabetes Federation Congress, 6-11 November 1994, Diabetes Research and Clinical Practice, Suppl.1, 222, 1994 15. P.Halvatsiotis, A.Papadopoulou, V.Haviaras, E.Anagnostou-Kakara, A.Yalouris, C.Sotiropoulos, S.A.Raptis: Comparison of the reliability of three different methods for the estimation of the glycated hemoglobin, 13th Congress of the European Association of Internal Medicine, 4-9 October 1995, Athens Greece, European Journal of Internal Medicine, Vol 6, Suppl.1, p133,1995, 16. Raptis A., Tountas N., Yalouris A., Halvatsiotis P.: Therapeutischer Effekt von Glibenclamid in einer fixen Kombination mit Metformin oder Phenfhormin in NIDDM Patienten, Diabetes Dreilaender-Tagung, 15-18 Mai, Basel, Switzerland 1996 17. P.Halvatsiotis, C.Makropoulos, S.A.Raptis: The National Diabetes Computed , Νetwork in Greece, 4th Meeting for the Implementation of the St-Vincent, Declaration, 26 February- 1 March 1997, Lisbon Portugal 18. P.G.Halvatsiotis, D.Turk, A.Alzaid, S.Dinneen, R.A.Rizza, K.S.Nair: Discordant metabolic actions of insulin on leucine and glucose metabolism in type II diabetes, 80th Annual Meeting of the Endocrine Society, June 24-27, 1998, New Orleans-LA, USA, June 24-27, 1998 19. Halvatsiotis P., Raptis A.E., Kantartzis K., Makropoulos C., Raptis S.A.: The National Diabetes Computed Network in Greece. Computers in Diabetes 1998, Barcelona- Spain, September 1998, Diabetes Nutrition and Metabolism Clin and Exp, Vol.11, N.1,52, Feb 1998 20. Halvatsiotis P.G., K.Short, M.Bigelow, K.S.Nair: Leucine metabolism in type II diabetes mellitus., 5th International Symposium on Amino Acid/Protein Metabolism in Health and Disease: “State of the Art at the Turn of the Millennium”, 23-25 September 1999, Perugia -Italy 21. P.G.Halvatsiotis, S.Meek, M.Bigelow, K.S.Nair: Dose dependent effect of insulinadministration on IGFs & IGF-BPs serum levels in healthy people at a postabsortive phase, 20th Congress of EASD, Brussels - Belgium, 28 September2 October 1999., Diabetologia, 0753, 1999 22. Halvatsiotis P., A.E.Raptis, E.Anastasiou, P.Tsapogas, E.Boutati, S.A.Raptis:The Hellenic National diabetes network and the diabetes healthcare medical record., 7th DOIT (EASD Study Group) Workshop, 12-14 May 2000, Gubbio Italy 23. Raptis A.E., Dimitriadis G., Yalouris A., Mitrakou A., Kantartzis K., Sotiropoulos C., Halvatsiotis P., Poulsen U., Raptis S.A: Is the electronic medical record a step towards optimal management of diabetic patients? International Symposium on Computer and Diabetes Care, Rochester-U.S.A., 8-10 September 2000 24. Raptis A.E., Dimitriadis G., Yalouris A., Mitrakou A., Kantartzis K., Sotiropoulos C., Halvatsiotis P., Poulsen U., Raptis S.A: Is the electronic medical record a step towards optimal management of diabetic patients? Symposium on Computers in Diabetes 2000, Herzliya-Israel, 14-16 September 2000., Diabetes Nutrition and Metabolism Clin and Exp, Vol.13, N.4,231, August 2000 25. Halvatsiotis P., Raptis A.E., Anastasiou E., Tsapogas P., Boutati E., S.A.Raptis (on behalf of the Board Members of the Hellenic National Diabetes Center, Athens, Greece): Hellenic National Diabetes Network and Diabetes Healthcare Medical Record., Symposium on Computers in Diabetes 2000, Herzliya-Israel, 14-16 September 2000., Diabetes Nutrition and Metabolism Clin and Exp, Vol.13, N.4, 247,August 2000 26. Short K.R., P.Halvatsiotis, M.Bigelow, K.S.Nair: Muscle fatiguability but not peak muscle strength or VO2max is altered in type II diabetic subjects.Annual Meeting of the American Sports Medicine Society, Indianapolis-IN, USA 2000., Med.Sci.Sports Exer. 32: S176, 2000 27. Sreekumar R., P.Halvatsiotis, K.Sreekumaran Nair: Gene expression profile in skeletal muscle of type 2 diabetic patients – A study using GeneChip array, 60th Annual Meeting of American Diabetes Association, 9-13 June, San Antonio-TX, USA, 2000. Late Breaking Research Abstracts LB-2 28. Halvatsiotis P., Raptis A.E., Anastasiou E., Tsapogas P., Boutati E., S.A.Raptis (on behalf of the Board Members of the Hellenic National Diabetes Center, Athens, Greece): Hellenic National Diabetes Network and Diabetes Healthcare Medical Record, International Symposium on Computer and Diabetes Care, Rochester-U.S.A., 8-10 September 2000 29. Halvatsiotis P., K.Short, M.Bigelow, K.S.Nair: Whole body leucine metabolism and muscle protein synthesis in type 2 diabetes, 60th Annual Meeting of American Diabetes Association, 9-13 June, San Antonio-TX, USA, 2000.Diabetes, 49, Suppl. 1, A84, 2000 30. Raptis S.A., P.G.Halvatsiotis, E Boutati, A.E.Raptis: A National Diabetes Service – the Greek experience, 3rd HbA1c International Symposium “Diabetes Mellitus: Time for a change”, Marrakech – Morocco, February 22-25, 2001 31. Short K.R., P.Halvatsiotis, M.Bigelow, K.S.Nair: Muscle mitochondrial and sarcoplasmic protein synthesis rates in type II diabetic patients Annual Meeting of Experimental Biology, Orlando-FL, USA March 31-April 4 2001 32. Raptis, A. EYalouris. A., Dimitriadis G, Halvatsiotis., P.,. Hatziagelaki, E Boutati, E.. Raptis S. A: The beneficial effect on metabolic parameter on type 2 diabetic patients through the use of the electronic medical records18th International Diabetes Federation Congress, Paris-France, 24-29 August 2003 33. Halvatsiotis P.G., Stefanopoulou S., Kotanidou A., Orfanos S., Martinos C., Roussos C., Economopoulos T., Raptis S. A.: The relation of thyroid hormone levels and reduced insulin sensitivity to survival of patients with septic shock 22nd Symposium of the International Danube-Symposia on Diabetes Mellitus – 2nd Central European Diabetes Congress, Kos Island, Greece, 7-9 June 2007 34. P. G. Halvatsiotis, S. Stefanopoulou, A. Kotanidou, S. Orfanos, C. Martinos, C. Roussos, T. Economopoulos, S. A. Raptis: Insulin resistance in sepsis and mitochondrial dysfunction as markers for the outcome of a septic shock., 43rd EASD Annual Meeting, Amsterdam, 17-21 September 2007 35. P. G. Halvatsiotis, K. Patsouras, E. Delatola, E. Boutati, G. Salamalekis, E. Salamalekis, T. Economopoulos, S.A. Raptis: Dysfunction of placental mitochondria in gestational diabetes, 44th EASD Annual Meeting, Rome, 8-11 September 2008 36. P.G. Halvatsiotis, K. Patsouras, G. Salamalekis, E.l Salamalekis, Th.Economopoulos, S.A. Raptis: Skeletal Muscle Mitochondrial Function in Advanced Pregnancy with Gestational Diabetes. 68th Scientific Sessions, San Francisco - CA, June 6-10 2008 37. P. G. Halvatsiotis, K. Patsouras, E. Delatola, G. Salamalekis, E. Salamalekis, Th. Economopoulos, S. A. Raptis: Skeletal Muscle Heavy Chain (MHC) Transcripts in Gestational Diabetes (GDM). 69th Scientific Sessions, New Orleans - LA, June 5-9 2009 38. P. G. Halvatsiotis, K. Patsouras, M. Vythoulka, G. Salamalekis, M. Tsilika, E. Salamalekis, Th.Economopoulos: Oxidative Load and Antioxidant Enzyme Capacity in Gestational Diabetes., 70th Scientific Sessions, Orlando - Florida, June 25-29 2010 39. P. Halvatsiotis, C. Patsouras, L. Batalias, M. Tsilika, P. Dimakou, B. Sioulas, D. Kassanos, G. Dimitriadis: Skeletal myscle myosin heavy chain isoform gene transcript levels in advanced pregnancy with gestational diabetes., 6th International Symposium on Diabetes & Pregnancy, Salzburg-Austria, March 2426 2011 40. P.Panagopoulos, P.Halvatsiotis, A.Likakis, Ch.C.Christodoulaki, E.Maratou, Z.Drakopoulou, D.Kassanos, G.Dimitriadis. Pre-eclampsia risk factors in the Greek population, Chicago, IL, USA, 9-11/9/2011, 41. P.Halvatsiotis, P.Karakitsos, K. Patsouras, M.Alepaki, L. Batalias, B. Sioulas, D. Kassanos, G. Dimitriadis: Circulating Vascular Endothelial growth factor receptor1 (SVEGFR-1) and receptor -2 (SVEGFR-2) in euglacemic gestational diabetes. 47th EASD Annual Meeting, Lisbon, 12-16 September 2011 42. P.Halvatsiotis, P.Karakitsos, K.Patsouras, E.Maratou, M.Tsilika, M.Alepaki, L.Batalias, Ch.Chrelias, Z.Drakopoulou, E.Maratou, D.Kassanos, G.Dimitriadis: Circulating cytokines, chemokines and adhesion molecules in euglycemic gestational diabetes, 9th World Congress on Insulin Resistance, Diabetes, and Cardiovascular Disease, Los Angeles, CA, USA, 3-5/11/2011 PEER REVIEWED PAPERS 1. Dimitriadis G., S. Raptis, A. Raptis, E. Hatziagelaki, A. Mitrakou, P. Halvatsiotis, S. Ladas, I. Hillebrand. : Effects of two new α-Glucosidase Inhibitors on glucemic control in patients with Insulin-Dependent Diabetes Mellitus. Klinische Wochenschrift 64, 405-410, 1986 (ΣΥΝ 18) II) `Hadjidakis, D.J., P.G.Halvatsiotis, Y.J.Ioannou, P.J.Mavrokefalos, S.A.Raptis.: The effects of the somatostatin analogue SMS 201-995 on carbohydrate homeostasis of insulin-dependent diabetics as assessed by the artificial endocrine pancreas. Diab.Res.Clin.Pract 5: 91-981988 (ΣΥΝ 19) III) Raptis A.E., N.B. Tountas, A.G. Yalouris, P.G. Halvatsiotis, S.A. Raptis: Therapeutic effect of glibenclamide in a fixed combination with metformin or phenformin in NIDDM patients. Hormone Metabolic Research 28,89-94, 1996 (ΣΥΝ 20) IV) P.G.Halvatsiotis, D.Turk, A.Alzaid, S.Dinneen, R.A.Rizza, K.S.Nair Insulin effect on leucine kinetics in type II diabetes mellitus Diabetes, Nutrition & Metabolism 15:136-142, 2002 (ΣΥΝ 21) V) R,Sreekumar, P.G.Halvatsiotis, J.C.Schimke, K.S.Nair Gene expression profile in skeletal muscle of type 2 diabetes and the effect of insulin treatment Diabetes 51:1913-1920, 2002 (ΣΥΝ 22) VI) P.G.Halvatsiotis, K.Short, M.Bigelow, K.S.Nair Synthesis rate of muscle proteins, muscle functions, and amino acid kinetics in type 2 diabetes Diabetes 51:2395-2404, 2002 (ΣΥΝ 23) VII) Jaleel A, Halvatsiotis P, Williamson B, Juhasz P, Martin S, Nair KS Identification of Amadori-modified plasma proteins in type 2 diabetes and the effect of short-term intensive insulin treatment. Diabetes Care. 2005 Mar;28(3):645-52 (ΣΥΝ 24) VIII) Theodossiadis P, Rouvas A, Nakopoulou L, Halvatziotis P, Magkou C, Vergados I: Epithelioid trophoblastic tumor , OPHTHALMOLOGY 2007, 114 (7): 1421-1422 2007