Sheffield Cancer Research Centre Newsletter
Issue 10 – April 2014
Sheffield Cancer Research Centre on Facebook and
Twitter
A mystery prize will be given to the person with the Xth number of ‘likes’ on Facebook or
‘follower’ on Twitter.
www.facebook.com/sheffieldcancerresearchcentre or
www.twitter.com/sheffieldcrc
Sheffield Public Discover Sheffield Cancer Research
Weston Park Hospital Cancer Charity, Yorkshire Cancer Research and Cancer
Research UK all hosted stands showcasing some of the amazing research
undertaken in the Sheffield Cancer Research Centre.
Weston Park Hospital Cancer Charity with the help of Professor Ingunn Holen's
group described how human and animal bones are used to investigate how cancer
spreads to the bones. The visitors tested the breaking strain of bones that had been
treated in different ways and heard about the research into why cancer cells can
remain dormant in the bone and then start to grow many years later.
David Booker talks bones at Discovery Night
Ingunn Holen talks bone metastasis
Yorkshire Cancer Research with the help of Dr Andy Chantry showed how Game
Technology can be used to help understand how cancer interacts with the bone
microenvironment. Nikki and Lindsey from YCR created tumour busting viruses from
sweets, marshmallows and cocktail sticks.
Game Technology Against Cancer
Nikki and Linsey make tumour-busting viruses
Cancer Research UK with the help of Juhi Misra , Gaynor Miller and Robin Rumney
explained how chemotherapy is developed to target specific cancers and Andy
Wilson squished another punnet of strawberries.
Robin and Juhi are aided by some junior
doctors as they target chemotherapy
Andy Wilson Extracts DNA from his 1,000,000th Strawberry
Bone Oncology Workshop – 21st May 2014
13:45 Tea/Coffee/Danish Pastries
14:00-17:00 Workshop – Speakers include: Rob Coleman, Tim Skerry, Janet Brown, Ingunn Holen,
Allie Gartland, Shelly Lawson, Penny Ottewell
17:00 Drinks Reception
Inox Conference Suite, Level 5, Students' Union Building, Durham Road, Sheffield, S10 2TG,
Register at the link below
http://www.sheffield.ac.uk/sheffield-cancer-research-centre/workshops/1.367406
Diary Dates
Seminar Series – for information, please see: http://www.shef.ac.uk/sheffield-cancer-researchcentre/news-and-events/seminar-series
Summer series now available.
Friday 25th April 2014, SCRC Visit - Dominique & Marie-Françoise Heymann
12:45-14:00 – LT3, F Floor, Medical School
Therapeutic approaches of bone sarcomas by targeting the tumor microenvironment
Dominique Heymann, Nantes University
Calcified arteries and bone sarcomas: a common functional microenvironment
Marie-Françoise Heymann, Nantes University
26th April 2014 – 14th Fund-raising Fancy Dress Ball
Organised by Mrs Michele France BEM
Venue – The Hubs, Sheffield City Centre, Paternoster Row
Fun begins at 8pm till 2am
Tickets £5 and can be purchased from Mrs Sarah Jackson, FU20, F floor, Medical School.
All proceeds to Department of Oncology’ Breast Cancer Research
14th May 2014 – Internal Seminar
13.00-14.00 – LT3, F Floor, Medical School
Trojan horse therapy for multiple myeloma
Simon Tazzyman, Sheffield Myeloma Research Team, Department of Oncology
Human PIF1 helicase supports cell growth under oncogenic-stress
Lisa Gagkou, Academic Unit of Molecular Oncology
21st May 2014 - Bone Oncology Workshop
14:00-17:00 – followed by a drinks reception
Inox Conference Suite, Level 5, Students' Union Building, Durham Road, Sheffield, S10 2TG,
Register at the link below
http://www.sheffield.ac.uk/sheffield-cancer-research-centre/workshops/1.367406
21st May 2014 – After Cancer Treatment: What now? A DVD guide for teenagers and young people
after cancer – Film Premier
18.00 – Firth Hall, University of Sheffield
FESTIVAL OF LIFE
Target Audience: General public, school/college groups aged 16+, young people and young people
recovering from cancer.
Booking: http://www.sheffield.ac.uk/life
23rd May 2014 – ‘How does it feel to be diagnosed and treated for breast cancer?’ – A Film and Panel
Discussion
15.00 – John Carr Design Suite, Portabello Centre, Pit Street (off West Street), Sheffield. S1 4ET
Hosted by Professor Malcolm Reed, Head of Department of Oncology
FESTIVAL OF MEDICINE, SCIENCE & HEALTH
Target Audience: General public, school/college groups aged 16+
Booking: http://www.sheffield.ac.uk/life
28th May 2014 – External Seminar
13.00-14.00 – LT3, F Floor, Medical School
Notch signalling in breast cancer
Keith Brennan – The Faculty of Life sciences, University of Manchester – (hosted by Nasreen Akhtar)
11th June 2014 – Internal Seminar
13.00-14.00 – LT3, F Floor, Medical School
The role of metformin in breast cancer
Sirwan Hadad, Department of Oncology
Dormancy of prostate cancer in bone
Freyja Docherty – Department of Human Metabolism
12th June 2014 – Making it happen: provision of services for people living with and beyond cancer
17.30 - Drinks reception, 18.30 Lecture – Richard Roberts building, University of Sheffield
Speakers: Mark Tami MP for Alyn & Deeside and Dr Adrienne Morgan, Independent Cancer Patients
Voice Charity
Chair: Prof Rob Coleman, YCR Professor of Medical Oncology, University of Sheffield
Panel discussion:
Mark Tami
(MP for Alyn & Deeside)
Adrienne Morgan
(Independent Cancer Patients Voice Charity)
Bronwen Shaw
(Anthony Nolan – Senior Clinical Scientist and Chief Medical Officer)
Will Cleary-Gray
(Sheffield Cancer Commissioner)
Dr Karen Robb
(Cancer Rehabilitation Strategy Development Manager,
Macmillan Cancer Support)
Booking: http://www.sheffield.ac.uk/sheffield-cancer-research-centre/patient-public-information/makingit-happen
18th June 2014 – External Seminar
13.00-14.00 – LT3, F Floor, Medical School
What’s out of LINE in cancer? (Non-coding RNA in cancer).
Christina Tufarelli – University of Nottingham - (hosted by Vicky James)
25th June 2014 - YCR Annual Scientific Meeting 2014
The Annual YCR Scientific meeting will be held at the Pavilions of Harrogate on Wednesday 25 th June
2014. Registration will open in February 2014. For further details – www.ycr.org.uk
9th July – Internal Seminar
13.00-14.00 – LT3, F Floor, Medical School
Myeloma Talk
Clive Buckle, Sheffield Myeloma Research Team, Department of Oncology
DNA replication stress in CHK1 depleted tumour cells triggers premature (S-phase) mitosis through
inappropriate activation of Aurora kinase B
Pedro Zuazua-Villar - Academic Unit of Molecular Oncology, Department of Oncology,
15th July 2014 – External Seminar
13.00-14.00 – LT3, F Floor, Medical School
Magnetic Materials in Medicine: Applications in Diagnosis, Management, and Treatment of Disease
Tim St Pierre – The University of Western Australia, Perth - (hosted by Matthew Bryan)
23rd July – External Seminar
13.00-14.00 – LT3, F Floor, Medical School
Biological and Clinical Significance of Chronic Herpes Virus infection in Patients treated for
Haematological Malignancies
David Lewis – University of Birmingham - (hosted by Andrew Chantry)
Funding Opportunities
Please see the Oncology Funding Opportunities Website for all the latest application details and new
calls:
http://www.shef.ac.uk.eresources.shef.ac.uk/oncology/staff-info/fundingopps
Project Title: 3rd NIHR Invention for Innovation (i4i) Challenge Awards call in the area of
regenerative medicine or biological therapeutics for cancer
NOW OPEN – DEADLINE 21st May 2014
Details: The NIHR i4i Challenge Awards addresses particular ‘challenges’ that are a priorities for the
NHS.
The programme will seek to identify those medical technologies with the greatest potential clinical
benefit, along with how they might be integrated into clinical decision and treatment pathways and how
they might be implemented on a large scale. The Challenge Awards will seek to support a team
capable in developing and supporting a programme of work for the further development of the
technology's clinical utility, including its broader applicability. Deadline: 21 May 2014
Stand Up To Cancer-Cancer Research UK Translational Research Fellowship
NOW OPEN – DEADLINE 12 NOON 28th July 2014
Details: http://www.cancerresearchuk.org/science/funding/find-grant/all-funding-schemes/stand-up-tocancer-cancer-research-uk-translational-research-fellowships/
The American Association for Cancer Research (AACR), on behalf of Stand Up To Cancer (SU2C) and
Cancer Research UK, is accepting applications for SU2C-Cancer Research UK Translational Research
Fellowships that will offer up to $315,000 each in research funding.
The grants provides four years of research fellowship support to the most talented and promising earlycareer investigators in the United States and the United Kingdom who have completed their Ph.D. or
clinical training and demonstrate clear potential to become leaders in their fields. Research projects
must be translational in nature and address critical problems in cancers with the potential to deliver
patient benefit.
Fellows funded through this initiative will gain translational research training in top U.S. and U.K.
research institutions, allowing them to develop their own ideas and preparing them to establish and
lead their own research groups, towards becoming outstanding leaders in their own fields. Proposals
must include plans to promote new significant transatlantic collaborations and active exchange of
knowledge and expertise between the United States and the United Kingdom.
Breast Cancer Research Award Breakthrough Awards Levels 1 and 2
Award amount max: Not specified
DEADLINE 14th May 2014
US Department of Defense (DoD), US
The award will fund high-impact research, encourage innovation and stimulate creativity, and facilitate
productive collaborations in the field of breast cancer research. The estimated budget of US$39 million
will be divided between approximately 30 projects. The award level 1 is worth up to US$350,000 and
level 2 up to US$700,000 plus indirect costs for up to three years.
Details: https://www.researchprofessional.com/funding/opportunity/1433462?__mhid=58885649
Breast Cancer Research Award Breakthrough Awards Levels 3 and 4
US Department of Defense (DoD), US
Award amount max: Not specified
DEADLINE 14th May 2014
The award will fund high-impact research, encourage innovation and stimulate creativity, and facilitate
productive collaborations in the field of breast cancer research. The estimated budget of US$40 million
will be divided between approximately eight projects. The award level 1 is worth up to US$2.5m and
level 4 up to US$10m plus indirect costs for up to five years.
Details: https://www.researchprofessional.com/funding/opportunity/1433464?__mhid=58885649
Call for Centre News Stories
What exciting developments are taking place in your research and training?
We need to show what great work is going on in Sheffield, not least so that we demonstrate our
strengths to potential funders.
We need to shout about:
* New research findings, particularly published papers
* Recently funded studies at start up
* Prizes or awards received
* Innovations in equipment/treatment
* Your involvement in public events
* Anything else you feel you would like to publicise
If you are working with the press offices at CRUK, YCR, the University or the Trust to publicise anything
please also keep me in the loop.
Please see the website for examples
http://www.sheffield.ac.uk/sheffield-cancer-research-centre/news-and-events/news/1.198922
Please send anything of interest to Lance Burn (l.burn@sheffield.ac.uk) - it doesn't have to be in a
publishable format as I can help with putting it together, writing text, obtaining pictures etc.