CR-UK/YCR Sheffield Cancer Research Centre SEMINAR SERIES Wednesdays 1-2pm Lecture Theatre 3, F Floor, Medical School All staff and students welcome 11th September Drosophila SOCS36E negatively regulates JAK/STAT pathway signalling via two separable mechanisms Jay Stec – Biomedical Sciences Lysyl oxidase mediates breast cancer metastasis to bone Robin Rumney – Human Metabolism 25th September - EXTERNAL SEMINAR Targeting DNA Base Excision Repair for Personalized Cancer Therapy Dr S. Madhusudan, Head of Translational DNA Repair Group University of Nottingham (Hosted by Rob Coleman) 2nd October – Extraordinary Seminar TBC James Bradford – Astra Zeneca 8th October – Extraordinary Seminar TBC Sebastien Serres 9th October DNA Analysis and Biomarkers in Oral Cancer Ibtisam Zargoun – Dental School Factors influencing survival in lung cancer across symptomatic presentations Vicky Athey, Rotherham General Hospital 16th October – Extraordinary Seminar Interplay between nucleosome repositioning, DNA methylation and transcription factor rearrangement during stem cell development. Vladimir Teif - BioQuant & German Cancer Research Centre In Neuenheimer Feld 23rd October - EXTERNAL SEMINAR Targeting the tumour microenvironment of high grade serous ovarian cancer Professor Francis Balkwill, Institute of Cancer Barts & The London School of Medicine & Dentistry (hosted by Professor Claire Lewis) 13th November Mass spectrometry imaging techniques (MALDI-MSI) in tumour vascular-targeted treatment strategies Laura Cole - Oncology/Sheffield Hallam University The role of miR-196a and HOXB9 in head and neck cancer Lav Darda – Dental School 27th November – EXTERNAL SEMINAR TBC Professor John Radford, Professor of Medical Oncology/Honorary Consultant, University of Manchester (hosted by Rob Coleman) 11th December The role of LARG in cellular responses to DNA damage and replication stress Ryan Beveridge – Academic Unit of Molecular Oncology, Department of Oncology How does providing an oral history in cancer and palliative care influence well-being of those who receive it? Michelle Winslow, Academic Unit of Supportive Care, Department of Oncology For further information or to suggest a speaker contact Dr Lance Burn (l.burn@sheffield.ac.uk)