Sheffield Cancer Research Centre Newsletter
Issue 11 – May 2014
Professor Martin Thornhill wins Samuel Charles Miller
Award 2014.
The Samuel Charles Miller Award is the most prestigious award of the American
Academy of Oral Medicine. It has been awarded each year since 1960 in honor of the
Academy’s founder Samuel Charles Miller. This year, for the first time ever, it has
been awarded to someone from the United Kingdom - Professor Martin Thornhill.
Martin is Professor of Translational Research in Dentistry at the University of
Sheffield. The award was made at the first joint meeting of the American Academy of
Oral Medicine, the European Association of Oral medicine, the British Society for Oral
Medicine and the Oral Medicine Academy of Australasia held in Orland, Florida 9-12th
April 2014.
Professor Thornhill was nominated by the Fellowship and Awards Committee for outstanding
contributions in the field of Oral Medicine and his research into new diagnostic technologies for the
diagnosis of potentially malignant oral lesions, development of human tissue engineered models of
oral dysplasia and oral cancer to facilitate research into these diseases and work on new drug
delivery technologies for treating oral cancer. The awardee is required to present a paper in the field
of Oral Medicine representative of his/her work at the time of the award. The purpose of the award
shall be to honor Samuel Charles Miller, the founder of the American Academy of Oral Medicine.
Professor Thornhill’s Samuel Charles Miller lecture covered his research on new diagnostic
technologies, new drug delivery systems and tissue engineered models of disease as well as other
aspects of his oral medicine research.
Martin Thornhill qualified in medicine at the University of London in 1978 and in dentistry in 1982.
He was awarded an MSc in 1986, PhD in 1990 and become an Oral Medicine consultant in 1992.
He was appointed Chair of Medicine in Dentistry at the University of Manchester in 1994 and Chair
of Clinical Oral Sciences at Bart’s and the London in 1998. He then become Chair of Dental
Diagnostic Sciences at the University of Texas Health Sciences Centre, San Antonio in 2002. In
2005 he was recruited to the Chair of Oral Medicine at the University of Sheffield, UK where in
2013, in recognition of his basic, translational and clinical research, he became Professor of
Translational Research in Dentistry. He is a Fellow of the Royal Colleges of Surgeons of Edinburgh
(1988), Ireland (1992) and London (2002), and has published ~150 papers and received more than
$12.5 million in research funding.
Diary Dates
Seminar Series – for information, please see: http://www.shef.ac.uk/sheffield-cancer-researchcentre/news-and-events/seminar-series
Summer series now available.
Friday 25th April 2014, SCRC Visit - Dominique & Marie-Françoise Heymann
12:45-14:00 – LT3, F Floor, Medical School
Therapeutic approaches of bone sarcomas by targeting the tumor microenvironment
Dominique Heymann, Nantes University
Calcified arteries and bone sarcomas: a common functional microenvironment
Marie-Françoise Heymann, Nantes University
26th April 2014 – 14th Fund-raising Fancy Dress Ball
Organised by Mrs Michele France BEM
Venue – The Hubs, Sheffield City Centre, Paternoster Row
Fun begins at 8pm till 2am
Tickets £5 and can be purchased from Mrs Sarah Jackson, FU20, F floor, Medical School.
All proceeds to Department of Oncology’ Breast Cancer Research
14th May 2014 – Internal Seminar
13.00-14.00 – LT3, F Floor, Medical School
Trojan horse therapy for multiple myeloma
Simon Tazzyman, Sheffield Myeloma Research Team, Department of Oncology
Human PIF1 helicase supports cell growth under oncogenic-stress
Lisa Gagkou, Academic Unit of Molecular Oncology
21st May 2014 - Bone Oncology Workshop
14:00-17:00 – followed by a drinks reception
Inox Conference Suite, Level 5, Students' Union Building, Durham Road, Sheffield, S10 2TG,
Register at the link below
http://www.sheffield.ac.uk/sheffield-cancer-research-centre/workshops/1.367406
21st May 2014 – After Cancer Treatment: What now? A DVD guide for teenagers and young people
after cancer – Film Premier
18.00 – Firth Hall, University of Sheffield
FESTIVAL OF LIFE
Target Audience: General public, school/college groups aged 16+, young people and young people
recovering from cancer.
Booking: http://www.sheffield.ac.uk/life
23rd May 2014 – ‘How does it feel to be diagnosed and treated for breast cancer?’ – A Film and Panel
Discussion
15.00 – John Carr Design Suite, Portabello Centre, Pit Street (off West Street), Sheffield. S1 4ET
Hosted by Professor Malcolm Reed, Head of Department of Oncology
FESTIVAL OF MEDICINE, SCIENCE & HEALTH
Target Audience: General public, school/college groups aged 16+
Booking: http://www.sheffield.ac.uk/life
28th May 2014 – External Seminar
13.00-14.00 – LT3, F Floor, Medical School
Notch signalling in breast cancer
Keith Brennan – The Faculty of Life sciences, University of Manchester – (hosted by Nasreen Akhtar)
11th June 2014 – Internal Seminar
13.00-14.00 – LT3, F Floor, Medical School
The role of metformin in breast cancer
Sirwan Hadad, Department of Oncology
Dormancy of prostate cancer in bone
Freyja Docherty – Department of Human Metabolism
12th June 2014 – Making it happen: provision of services for people living with and beyond cancer
17.30 - Drinks reception, 18.30 Lecture – Richard Roberts building, University of Sheffield
Speakers: Mark Tami MP for Alyn & Deeside and Dr Adrienne Morgan, Independent Cancer Patients
Voice Charity
Chair: Prof Rob Coleman, YCR Professor of Medical Oncology, University of Sheffield
Panel discussion:
Mark Tami
(MP for Alyn & Deeside)
Adrienne Morgan
(Independent Cancer Patients Voice Charity)
Bronwen Shaw
(Anthony Nolan – Senior Clinical Scientist and Chief Medical Officer)
Will Cleary-Gray
(Sheffield Cancer Commissioner)
Dr Karen Robb
(Cancer Rehabilitation Strategy Development Manager,
Macmillan Cancer Support)
Booking: http://www.sheffield.ac.uk/sheffield-cancer-research-centre/patient-public-information/makingit-happen
18th June 2014 – External Seminar
13.00-14.00 – LT3, F Floor, Medical School
What’s out of LINE in cancer? (Non-coding RNA in cancer).
Christina Tufarelli – University of Nottingham - (hosted by Vicky James)
25th June 2014 - YCR Annual Scientific Meeting 2014
The Annual YCR Scientific meeting will be held at the Pavilions of Harrogate on Wednesday 25 th June
2014. Registration will open in February 2014. For further details – www.ycr.org.uk
9th July – Internal Seminar
13.00-14.00 – LT3, F Floor, Medical School
Myeloma Talk
Clive Buckle, Sheffield Myeloma Research Team, Department of Oncology
DNA replication stress in CHK1 depleted tumour cells triggers premature (S-phase) mitosis through
inappropriate activation of Aurora kinase B
Pedro Zuazua-Villar - Academic Unit of Molecular Oncology, Department of Oncology,
15th July 2014 – External Seminar
13.00-14.00 – LT3, F Floor, Medical School
Magnetic Materials in Medicine: Applications in Diagnosis, Management, and Treatment of Disease
Tim St Pierre – The University of Western Australia, Perth - (hosted by Matthew Bryan)
23rd July – External Seminar
13.00-14.00 – LT3, F Floor, Medical School
Biological and Clinical Significance of Chronic Herpes Virus infection in Patients treated for
Haematological Malignancies
David Lewis – University of Birmingham - (hosted by Andrew Chantry)
Funding Opportunities
Please see the Oncology Funding Opportunities Website for all the latest application details and new
calls:
http://www.shef.ac.uk.eresources.shef.ac.uk/oncology/staff-info/fundingopps
Project Title: 3rd NIHR Invention for Innovation (i4i) Challenge Awards call in the area of
regenerative medicine or biological therapeutics for cancer
NOW OPEN – DEADLINE 21st May 2014
Details: The NIHR i4i Challenge Awards addresses particular ‘challenges’ that are a priorities for the
NHS.
The programme will seek to identify those medical technologies with the greatest potential clinical
benefit, along with how they might be integrated into clinical decision and treatment pathways and how
they might be implemented on a large scale. The Challenge Awards will seek to support a team
capable in developing and supporting a programme of work for the further development of the
technology's clinical utility, including its broader applicability. Deadline: 21 May 2014
Stand Up To Cancer-Cancer Research UK Translational Research Fellowship
NOW OPEN – DEADLINE 12 NOON 28th July 2014
Details: http://www.cancerresearchuk.org/science/funding/find-grant/all-funding-schemes/stand-up-tocancer-cancer-research-uk-translational-research-fellowships/
The American Association for Cancer Research (AACR), on behalf of Stand Up To Cancer (SU2C) and
Cancer Research UK, is accepting applications for SU2C-Cancer Research UK Translational Research
Fellowships that will offer up to $315,000 each in research funding.
The grants provides four years of research fellowship support to the most talented and promising earlycareer investigators in the United States and the United Kingdom who have completed their Ph.D. or
clinical training and demonstrate clear potential to become leaders in their fields. Research projects
must be translational in nature and address critical problems in cancers with the potential to deliver
patient benefit.
Fellows funded through this initiative will gain translational research training in top U.S. and U.K.
research institutions, allowing them to develop their own ideas and preparing them to establish and
lead their own research groups, towards becoming outstanding leaders in their own fields. Proposals
must include plans to promote new significant transatlantic collaborations and active exchange of
knowledge and expertise between the United States and the United Kingdom.
Breast Cancer Research Award Breakthrough Awards Levels 1 and 2
Award amount max: Not specified
DEADLINE 14th May 2014
US Department of Defense (DoD), US
The award will fund high-impact research, encourage innovation and stimulate creativity, and facilitate
productive collaborations in the field of breast cancer research. The estimated budget of US$39 million
will be divided between approximately 30 projects. The award level 1 is worth up to US$350,000 and
level 2 up to US$700,000 plus indirect costs for up to three years.
Details: https://www.researchprofessional.com/funding/opportunity/1433462?__mhid=58885649
Breast Cancer Research Award Breakthrough Awards Levels 3 and 4
US Department of Defense (DoD), US
Award amount max: Not specified
DEADLINE 14th May 2014
The award will fund high-impact research, encourage innovation and stimulate creativity, and facilitate
productive collaborations in the field of breast cancer research. The estimated budget of US$40 million
will be divided between approximately eight projects. The award level 1 is worth up to US$2.5m and
level 4 up to US$10m plus indirect costs for up to five years.
Details: https://www.researchprofessional.com/funding/opportunity/1433464?__mhid=58885649
Call for Centre News Stories
What exciting developments are taking place in your research and training?
We need to show what great work is going on in Sheffield, not least so that we demonstrate our
strengths to potential funders.
We need to shout about:
* New research findings, particularly published papers
* Recently funded studies at start up
* Prizes or awards received
* Innovations in equipment/treatment
* Your involvement in public events
* Anything else you feel you would like to publicise
If you are working with the press offices at CRUK, YCR, the University or the Trust to publicise anything
please also keep me in the loop.
Please see the website for examples
http://www.sheffield.ac.uk/sheffield-cancer-research-centre/news-and-events/news/1.198922
www.facebook.com/sheffieldcancerresearchcentre or
www.twitter.com/sheffieldcrc
Please send anything of interest to Lance Burn (l.burn@sheffield.ac.uk) - it doesn't have to be in a
publishable format as I can help with putting it together, writing text, obtaining pictures etc.