Contents Executive summary ............................................................................................. 2 About this report .................................................................................................. 6 Background ......................................................................................................... 7 What is diabetes? ......................................................................................................................... 7 Risk factors .................................................................................................................................. 8 Complications of diabetes ............................................................................................................ 9 Measuring blood glucose ............................................................................................................11 Medicines for lowering blood glucose .........................................................................................12 Prevalence of diabetes ................................................................................................................12 Aboriginal and Torres Strait Islander people ...............................................................................14 Burden of disease .......................................................................................................................15 General practice ..........................................................................................................................17 Type 2 diabetes guidelines ................................................................................ 18 Australian guidelines on the management of diabetes ................................................................18 Risk assessment and screening ..................................................................................................19 Testing for type 2 diabetes ..........................................................................................................19 Initial evaluations and investigations ...........................................................................................21 Dietary and lifestyle interventions ................................................................................................22 Patient education and self-management .....................................................................................22 Treatment targets and glycaemic control ....................................................................................22 Blood glucose lowering medicines ..............................................................................................23 Management of absolute cardiovascular risk ..............................................................................28 Ongoing evaluations and investigations ......................................................................................28 Type 2 diabetes in young people ................................................................................................29 Gestational diabetes mellitus ......................................................................................................30 Use of medicines and medical tests ................................................................... 33 Medicines available for lowering blood glucose ..........................................................................33 Use of blood glucose lowering medicines ...................................................................................36 Exenatide ....................................................................................................................................39 Costs ...........................................................................................................................................40 Insulin pumps ..............................................................................................................................41 National Diabetes Services Scheme ...........................................................................................42 Medical test use ..........................................................................................................................43 Practice gaps and safety alerts .......................................................................... 46 Post market review Expert Reference Group deliberations .........................................................46 Diagnosis ....................................................................................................................................46 Treatment pathways ....................................................................................................................47 Treatment to target ......................................................................................................................51 Inappropriate prescribing.............................................................................................................53 Adherence to guidelines ..............................................................................................................54 Therapeutic inertia ......................................................................................................................56 Primary health of Aboriginal and Torres Strait Islander people ...................................................56 Access to health care ..................................................................................................................57 Risk factors .................................................................................................................................57 Safety alerts ................................................................................................................................58 4 document1 Consumer knowledge, attitudes and behaviours ................................................ 59 Attitudes towards having type 2 diabetes ................................................................................... 60 Consumer beliefs about the causes of diabetes ......................................................................... 61 Attitudes toward self-management ............................................................................................. 62 Attitudes towards diet and exercise ............................................................................................ 63 Knowledge, attitudes and behaviours relating to blood glucose lowering medicines .................. 65 Knowledge and attitudes towards blood glucose tests ............................................................... 70 Interaction with health professionals ........................................................................................... 72 Health literacy, knowledge, information and education ............................................................... 74 Blood glucose lowering medicine related enquires received by Medicines Line ......................... 75 Knowledge, attitudes and behaviours in Aboriginal and Torres Strait Islander people .................................................................................................. 77 Attitudes towards having diabetes .............................................................................................. 77 Beliefs about the causes of diabetes .......................................................................................... 78 Attitudes towards self-management ........................................................................................... 79 Attitudes towards diet and exercise ............................................................................................ 80 Knowledge, attitudes and behaviours relating to blood glucose lowering medicines .................. 82 Knowledge and attitudes relating to blood glucose tests ............................................................ 82 Interactions with and access to health care professionals .......................................................... 83 Culturally and linguistically diverse communities and type 2 diabetes ................ 85 Attitudes towards having type 2 diabetes ................................................................................... 85 Beliefs about the causes of diabetes .......................................................................................... 86 Attitudes towards diet and exercise ............................................................................................ 87 Knowledge, attitudes and behaviours relating to blood glucose lowering medicines .................. 89 Knowledge and attitudes relating to blood glucose tests ............................................................ 90 Interaction with health professionals ........................................................................................... 91 Health professional knowledge attitudes and behaviours ................................... 93 Risk assessment and screening ................................................................................................. 94 Testing for type 2 diabetes ......................................................................................................... 94 Change in HbA1c units ................................................................................................................ 95 Prescribing of blood glucose lowering medicines ....................................................................... 95 Monitoring of type 2 diabetes ................................................................................................... 101 Self-monitoring of blood glucose .............................................................................................. 102 Ongoing management of type 2 diabetes ................................................................................. 102 Differences between GPs and specialists regarding type 2 diabetes management ................. 103 Challenges encountered in managing type 2 diabetes ............................................................. 103 Management of GDM ............................................................................................................... 104 Nurses role in type 2 diabetes management ............................................................................ 105 Pharmacists role in type 2 diabetes management .................................................................... 106 Guidelines and resources used in practice ............................................................................... 107 Perceived patient information needs ........................................................................................ 107 Suggestions for a 2016 NPS MedicineWise program on diabetes ........................................... 107 NPS MedicineWise interventions ..................................................................... 109 Health care professional focused interventions ........................................................................ 109 Feedback from the field force on the 2012 visiting program ..................................................... 111 Feedback from the field force on a 2016 visiting program ........................................................ 113 Evaluation of the 2012 program................................................................................................ 114 Consumer focused interventions .............................................................................................. 115 5 document1 Aboriginal and Torres Strait Islanders programs .......................................................................116 RADAR publications ..................................................................................................................117 Recommendations from related NPS MedicineWise programs.................................................117 Other interventions .......................................................................................... 119 Diagnosis ..................................................................................................................................119 Comparisons of quality improvement strategies ........................................................................120 Reviews of specific quality improvement strategies ..................................................................123 Interventions for indigenous peoples .........................................................................................133 Culturally and linguistically diverse interventions ......................................................................133 Interventions to improve adherence ..........................................................................................133 Current Australian healthcare professional training ...................................................................134 Type 2 diabetes management and GP prescribing software ............................ 137 Diabetes-related tools and preventive health prompts ..............................................................137 Resources available to assist GPs to complete diabetes-related MBS items............................139 Identifying people with diabetes in GP prescribing software .....................................................140 Patient information resources ....................................................................................................140 Other GP software that can assist in the management of diabetes ...........................................141 Using MedicineList+ as diabetes management tool ..................................................................142 Environmental scan ......................................................................................... 143 Government policy ....................................................................................................................143 Media ........................................................................................................................................146 Stakeholders .............................................................................................................................147 Peak bodies ..............................................................................................................................147 Research bodies .......................................................................................................................149 Support services .......................................................................................................................149 Online diabetes keywords, searches and commentary .................................... 151 Internet search trends ...............................................................................................................151 Social media ..............................................................................................................................153 Appendix 1: Blood glucose lowering medicines – comparative information ...... 155 Appendix 2: List of Australian guidelines .......................................................... 157 Appendix 3: PBS restriction wordings .............................................................. 159 Appendix 4: Impact of QI strategies ................................................................. 162 Appendix 5: Search strategies ......................................................................... 163 document1