1 Chapter 3 Lesson 1 THE CELL CYCLE AND DIVISION The Cell Cycle The cell cycle is the cycle of growth, development, and division of most cells in an organism. The cell cycle makes it possible for organisms to grow and develop replace old or damaged cells, and produce new cells. To reproduce, a cell divides. Overview Phases of the Cell Cycle for Eukaryotic Cells Interphase Mitotic Phase The Interphase – 3 Stages G1, S, and G2 The Mitotic Phase 2 stages – mitosis followed by cytokinesis o Phases of Mitosis: Prophase, Metaphase, Anaphase, & Telophase Results of Cell Division reproduction, growth, replacement, and repair 2 Phases of the Cell Cycle for Eukaryotic Cells NOTE - Only eukaryotic cells undergo mitosis. 1. The interphase This is the period of the cell’s growth and development. 2. The mitotic phase (when mitosis takes place) This is the cell’s reproduction. Length of a Cell Cycle The length of time for a cell to complete the cell cycle depends on the type of cell. It may be a few minutes or even a year. Most dividing human cells take about 24 hours. The Interphase A cell spends most of its life in the interphase. The cell grows and prepares for cell division. The interphase has 3 stages. Three Stages of the Interphase 3 1. The G1 Stage (the longest part of the interphase) Rapid growth takes place. Organelles are replicated. Normal cell functions occur. o For example – stomach cells produce and put out digestive enzymes. The DNA is in the form of long, thin strands called chromatin. 2. The S Stage More growth takes place. Organelles are replicated. Chromosomes are replicated in the nucleus. o The cell’s DNA is copied. o The DNA is arranged as pairs of identical chromosomes called sister chromatids. o Sister chromatids are held together by a structure called the centromere. (See p. 88.) 4 3. The G2 Stage More growth, organelle replication, and cell functions occur. The cell stores energy that will be needed for cell division. 5 The Mitotic Phase It follows the interphase. It produces a pair of daughter cells. It occurs in two stages: 1. Mitosis o During mitosis the nucleus divides into two identical nuclei. o Mitosis occurs in four phases. 2. Cytokinesis o The cytoplasm divides with its contents, including the organelles. 6 Phases of Mitosis The process is continuous, but 4 phases are observed. 1. Prophase Duplicated chromosomes are present. The nucleolus disappears and the nuclear membrane breaks down. Spindle fibers form. 2. Metaphase Spindle fibers cause chromosomes to line up in a single file in the middle of the cell. 3. Anaphase Sister chromatids separate. Spindle fibers shorten and pull chromatids in opposite directions. o This leads to two separate identical sets of single-stranded chromosomes. Cell lengthens. 7 4. Telophase A nuclear membrane forms around each set of chromosomes in the two sides of the elongated cell. o This gives two new & identical nuclei. Spindle fibers begin to break down. After Mitosis: Dividing the Cell’s Components Cytokenisis is the process of the cell’s cytoplasm being divided. For Animal Cells The cell membrane contracts (squeezes together) to form a furrow in the middle of the cell. The furrow gets deeper until two separate cells form. For Plant Cells Vesicles join to form a disk, called a cell plate, down the middle of the cell. The cell plate grows toward the cell wall, forming a new cell wall. This results in two new daughter cells. 8 Results of Cell Division The cell cycle is important for: 1. reproduction in some organisms 2. growth in multicellular organisms 3. replacement of worn out or damaged cells, and 4. repair of damaged tissues. • In some unicellular organisms, cell division is a form of reproduction. • Cell division allows multicellular organisms to grow and develop from one cell. Fun Facts Each species has a characteristic number of chromosomes in each cell. Species Chromosomes human cell 46 guinea pig cell 64 gorilla cell 48 apple cell 34