Date: September, 2014
CURRICULUM VITAE
NAME: Bhupendra Singh Kaphalia, Ph.D.
PRESENT POSITION AND ADDRESS:
Professor
Director, Exposure Assessment & Biomarker Development Core (UTMB’s
NIEHS Center and Sealy Center for Environmental Health & Medicine)
Department of Pathology
University of Texas Medical Branch
Galveston, TX 77555-0438
Tel:
(409) 772-4995
FAX: (409) 747-1763
Email: bkaphali@utmb.edu
BIOGRAPHICAL:
Citizenship:
Business Address:
U.S.A.
The University of Texas Medical Branch
301 University Boulevard
Department of Pathology
Galveston, TX 77555-0438
(409) 772-4995
EDUCATION:
07/1971-05/1973
B.S.
Chemistry, Zoology, Botany
Agra University
Agra, India
07/1973-05/1975
M.S.
Chemistry
Kumaun University
Nainital, India
07/1980-5/1984
Ph.D.
Chemistry/Toxicology
Kumaun University
Nainital, India
PROFESSIONAL AND TEACHING EXPERIENCE:
09/2010-present
Professor
Department of Pathology
University of Texas Medical Branch
Galveston, TX
06/2006-present
Director
Exposure Assessment & Biomarker Development Core (UTMB’s NIEHS
Center and Sealy Center for Environmental Health & Medicine)
University of Texas Medical Branch
Galveston, TX
09/2002–08/2010
Associate Professor
Kaphalia, B.S.
Page 2
Department of Pathology
University of Texas Medical Branch
Galveston, TX
09/1998 – 08/2002
Assistant Professor
Department of Pathology
University of Texas Medical Branch
Galveston, TX
09/1988-08/1998
Instructor
Department of Pathology
University of Texas Medical Branch
Galveston, TX
06/1985-08/1988
Postdoctoral Fellow
Department of Pathology
University of Texas Medical Branch
Galveston, TX
09/1978-06/1985
Scientific Assistant
Industrial Toxicology Research Center
Lucknow, India
07/1977-08/1978
Research Fellow
Council of Scientific and Industrial Research
New Delhi, India
10/1976-06/1977
Research Fellow
World Health Organization
Industrial Toxicology Research Center
Lucknow, India
RESEARCH ACTIVITIES:
Area of Research
Objectives: To delineate the mechanisms of alcoholic pancreatitis and liver disease and develop
their biomarkers for early detection and prevention.
Approach: Major focus of my research program is to understand the metabolic basis of alcoholic
pancreatitis and liver disease, and to delineate their underlying mechanism(s). Our studies indicate
that one of the primary targets of alcohol toxicity in the pancreas as well in the liver is lipid
metabolism which can result into inflammation with or without fibrosis. Using hepatic alcohol
dehydrogenase-deficient deer mouse model, which mimics a metabolic condition observed in
chronic alcoholic patients, we found that metabolism of ethanol in the livers and alcohol levels in
the body are the determining factors in ethanol-induced pancreatic and hepatic injury. We are
using lipid metabolomic and proteomic approaches, and pathways’ analysis to delineate the
underlying mechanism(s) of alcoholic pancreatitis and hepatitis, and develop their early
biomarkers and therapeutic targets.
Grant support
Current
1U19ES020676-01U19, NIH/NIEHS.
Kaphalia, B.S.
Page 3
“Gulf Coast Health Alliance: Health Risks Related to the Macondo Spill (GC-HARMS)”
(PI - Elferink), Co- Investigator; 5% effort; total of $5,804,910; 06/01/2011 – 05/31/2016
5 P30 ES006676-15 NIH/NIEHS
“Cellular Response Mechanisms to Environmental Challenge”
(PI - Elferink), Co-Investigator, 7% Efforts; total of $5,225,000; 03/01/2012 – 03/31/2017
Pending
1R21AA023171-01, NIH/NIAAA
“MicroRNAs and Alcoholic Fatty Liver Disease”
Principal Investigator; 18% effort; total of $150,000; 04/01/14 – 03/31/16
1R21AA022820-01, NIH/NIAAA
“Mechanism(s) of Alcoholic Liver Disease”
Principal Investigator, 20% effort; total of $275,000, 09/01/13 - 08/31/15
R01, 1R01AI110358-01A1, NIH/NIAID
“Mechanisms of HCV Assembly”
Co-Investigator, 10% effort; total of $1,250,000; 07/01/14 - 06/30/19
R01, 1R01AA024403-01, NIH/NIAAA
Metabolic Basis of Alcoholic Pancreatitis
Principal Investigator, 30% efforts, total of $1,937,500.00; 07/01/15 - 06/30/20
Past
PPG, NS11255-32A2, NIH, NINDS (NCE)
“Peripheral and Central Sensitization in Pain.”
(PI -Chung), ROS-Analytical Core Director and PI; 10% efforts; total of $4,315,790
04/01/08 - 03/31/14
John Sealy Memorial Endowment Fund for Biomedical Research
“Dissecting the mechanisms of Alcoholic liver disease”
Principal Investigator, 5% Efforts; total of $50,000; 07/01/2013 - 06/30/2013
R21, AARAA019812A, NIH, NIAAA
“Mechanism(s) of Alcoholic Pancreatitis”
Principal Investigator, 20% effort; Total cost: $ 275,000; 08/01/10 – 07/31/13
R01, AA016364, NIH, National Institute on Alcohol Abuse and Alcoholism
“Hepatic Steatosis and Lipid Metabolome”
(P.I. - G.A.S. Ansari); Co-Investigator; 15% effort; Total cost $1,736,500; 10/01/07 – 09/31/13
R01, AA13171, NIH, NIAAA
“Fatty Acid Ethyl Esters in Ethanol-Induced Pancreatitis”
Principal Investigator; 50% effort; Total cost $1,303,750; 08/01/02 – 07/31/08
R01, ES11584, NIH, National Institute of Environmental Health Sciences
“Mechanism(s) of TCE-Mediated Autoimmunity”
(P.I. - G.A.S. Ansari); Co-Investigator; 10% effort; Total Cost $ 1,793,125; 07/01/00 - 06/31/10
R01, ES04185, NIH, NIEHS
Kaphalia, B.S.
Page 4
“Lipid Conjugates of Xenobiotics”
(P.I.- G.A.S. Ansari); Co-Investigator; 40% effort; Total cost $1,303,750; 06/01/00 - 05/31/05
ES006676-12, NIEHS Center Pilot grant
“Plasma Lipidomic and Proteomic Changes in Alcoholic Liver Disease”
Principal Investigator; 5% effort; Total cost $ 17,500; 5/01/06 – 04/30/07
Sealy Center for Environmental Health & Medicine, UTMB
“Early detection of alcoholic pancreatitis”
Principal Investigator; 5% effort; Total cost $ 8,200; 07/01/03 - 08/31/04
Chemical Manufacturers Association (CMA)
“Mechanism of 2-Butoxyethanol-Induced Hemolytic Anemia”
Principal Investigator; 20% effort; Total cost $77,118; 08/01/96 - 02/28/97
Chemical Manufactures Association (CMA)
“Mechanism of 2-Butoxyethanol-Induced Hemolytic Anemia”
Principal Investigator; 20% effort; Total cost $24,819; 01/01/95 - 06/30/95
R01, R819989, U.S. Environmental Protection Agency (EPA)
“Biomarkers of Chemical Exposure”
(P.I.- G.A.S. Ansari); Co-Investigator; 30% effort; Total cost $299,391; 10/01/92 - 09/31/95
Small Grant Program, UTMB
“Fatty Acid Conjugates of Chlorinated Phenols”
Principal Investigator; 5% effort; Total cost $12,480; 04/01/89 - 03/31/91
COMMITTEE RESPONSIBILITIES:
UTMB
Radiation Safety Committee, 1999-2005
Radioactive Drug Research Committee, 1999-2005
Director, Keiller ABSL-2 Facility, 2003-2006
TEACHING RESPONSIBILITIES:
A. TEACHING RESPONSIBILITIES AT UTMB:
a. Teaching
School of Medicine:
1988-2002
Integrated Curriculum Evaluation Exercise for 4th year medical students
2003- Present Facilitator, Essentials of Endocrinology & Reproduction (~50 hr/year).
2006Facilitator, Renal Course (~30 hr),
2009Facilitator, Pathobiology & Host Defense (~6 hr).
Graduate School:
1998-present
Associate member of Experimental Pathology Graduate program
2003-present
Biotransformation Core, NIEHS Center
1995
Principles and Practice of Gas Chromatography, Instrumental Methods of
Kaphalia, B.S.
Page 5
analysis in Drug Metabolism (graduate program in Experimental Pathology and
Toxicology)
2001
Molecular Toxicology: Molecular Damage-Lipid peroxidation and Free radicals
(graduate program in Experimental Pathology and Toxicology)
1998-present
Evaluation of posters and judging, Department of Pathology Research Day
(annual event)
1999-present
Evaluation of graduate student speakers, Teaching in Pathology (annual
event).
b. Students/Mentees/Advisees/Trainees:
Graduate students
2013-
Samir Mohamed Ahmed Amer, M.B.B.Ch
Forensic M. & Clinical Toxicology, Tanta, Egypt
Egyptian Cultural Bureau (Exchange Program)
Postdoctoral Fellows Trained:
2002-2006
2003-2005
2004-2006
2006-present
2007-present
2008-present
Ping Cai
Shagufta Khan
Swapna Sarkar
Dhananjaya Nauduri
Shakuntala Kodraganti
Harshika Fernando
Graduate Students Trained:
1986-1990
1996-2001
1997-1999
1998-2004
2004
2005
20122003-
Hari K. Bhat (Graduate student)
Steve M. Green (Graduate student)
Davis Daiker (Graduate student)
Kelly Mericle (Graduate student)
Anita Reno (Phospphatidylethanol; biomarker of ethanol); on rotation
Gogan C. Jenise (Mechanism of alcoholic pancreatitis); on rotation
Mentor, T-32 training grant entitled, “Surgical Research Training in GI Diseases,”
Department of Surgery, UTMB.
Mentor, T-32 training grant entitled, “Emerging and Tropical Infectious Disease
and Biodefense.” Department of Pathology, UTMB.
Undergraduate Students Trained:
1993
1993
1994
1994
1996
2008
2010
Hariharan Balasubramanian (Trapping of reactive intermediates)
Denis Sawyer (Biosynthesis of lipid conjugates of aniline)
James B. Carr (Isolation and characterization of benzene metabolites from mice
urine)
Tina Havel (Cholesterol oxidation via peroxynitrite generating system)
Tina Havel (Fatty acid anilides and Toxic Oil Syndrome)
Chandani Jain (Proteomics)
Nikhill Bharatdwaj (Proteomics of liver diseases (alcoholic and nonalcoholic)
Kaphalia, B.S.
Page 6
c. Chair/Member of Ph.D. Supervisory/Prelims Committee:
Dissertation committee of Dr. Kelly Mericle, 2004
Supervisory Committee of Ms. Anita Reno, 2006
Committee member of Ms. Heather Stevenson (Prelims I & II)
Committee member of Mr. Jeffery Jordan (Prelims I & II)
Supervisory and Dissertation committees of Ms. Sara Woodson, 2008
Supervisory Committee of John Ogunbileje, 2010
Supervisory Committee of Shayne Hassler, 2012
Dissertation committee of Eseosa Amy Bazuaye-Ekwuyasi, Masters of Med, Sci. 2014
MEMBERSHIP IN SCIENTIFIC SOCIETIES/PROFESSIONAL ORGANIZATIONS:
Academy of Environmental Biology, India
American Pancreatic Association
Association of Scientists of Indian Origin in America
American Chemical Society
International Society for the Study of Xenobiotics (ISSX)
International Society for Biomedical Research on Alcohol
Metabolomic Society
Research Society on Alcoholism
Society of Toxicology
HONORS:
Fourth rank (class size 48) in M.S.
Merit Scholarship - C.S.I.R. (Government of India)
ADDITIONAL INFORMATION:
Editorial Board:
Alcohol
Alcohol (Decision Editor)
Bulletin of Environmental Contamination & Toxicology
Euro-Asian Journal of Hepato-Gastroenterology*
Journal of Toxicology and Environmental Health B.
Journal of Experimental Zoology, India
The Open Drug Metabolism Journal
Toxicology Letters (2002-2005)
Journal Reviewer:
Alcohol
Alcoholism: Clinical & Experimental Research
Bulletin of Environmental Contamination and Toxicology
Cell Biology and Toxicology
Cell Communication and Signaling*
Clinica Chimica Acta
Clinical Chemistry and Enzymology
Comparative Biochemistry and Physiology
Drug Metabolism & Disposition
Eastern Research Group, Inc., under contract to USEPA
Euro-Asian Journal of Hepato-Gastroenterology*
Kaphalia, B.S.
Page 7
International Journal of Medical Sciences*
Journal of Comparative Physiology B
Journal of Experimental Zoology
Journal of Pulmonary & Respiratory Medicine
Journal of Toxicology
Journal of Toxicology and Environmental Health
Lipids
Molecular and Cellular Biochemistry
Pancreas
Pharmaceutical Biology*
Plosone*
Psychiatry Research
Toxicology Letters
Toxicology and Applied Pharmacology
Toxicology Mechanisms and Methods
Grant Reviewer:
2012 – 2016
2004 - 2012
2004 - Present
2004 – Present
2007
2009
2010 - Present
2011 - 2012
Member, AA 1 Study Section, NIAAA/NIH
Ad hoc Member, AA 1 Study Section of NIAAA/NIH
Ad hoc Member, AA-1 Study Section (fellowship), NIAAA/NIH
American Association of Advancement of Science
Terry Fox Fund for Cancer Research, United Arab Emirates
CSR, NIH (American Recovery and Reinvestment Act grants)
CSR, NIH
Special Emphasis Panel, ZAA1 JJ (01)
(Alcohol-Induced Metabolic and Hepatic Injury, AIMHI, NIH/NIAAA)
Professional Skills:
1979
Indo-U.S. Workshop on Biodegradable Pesticides
Industrial Toxicology Research Center, Lucknow, India
1980
Short-term two months course: Food Contaminants Monitoring Program
Sponsored by Food and Agriculture Organization (FAO) and United Nations
Organization (UNO), International Food Technological Research Institute,
Mysore, India
1984
ITRC-IBRO Symposium
Neurotoxic Substances and Their Impact on Human Health
1991
Continuing Education Course: Introduction to Physiologically
Based Pharmacokinetic Modeling
Society of Toxicology
Dallas, TX
1992
Continuing Education Course: Implementing PBPK
Interactive Computer Session.
Society of Toxicology
Seattle, WA
1995
Continuing Education Course: Advanced Methods
in Molecular Biology for Toxicologists.
Society of Toxicology
Baltimore, MD
Kaphalia, B.S.
Page 8
1996
Risk Assessment Mini Course (~ 20 hrs)
Sponsored by Toxicology Training Grant, UTMB
1996
Continuing Education Course: Quantitative Analysis in Risk Assessment: Monte
Carlo Techniques
Society of Toxicology
Anaheim, CA
1997
Continuing Education Course: Cell Signaling in Toxicology
Society of Toxicology
Cincinnati, OH
2001
Continuing Education Course: Choosing Tools for Toxicogenomics: A Primer for
the Research Scientist. Society of Toxicology, San Francisco, CA.
2002
Mechanism of Alcoholic Pancreatitis, Nov. 12-13, 2002, Chicago, IL, Sponsored
by NIAAA, ORD/NIDA
2004
Mechanism of Alcohol-Associated Cancers, Oct 6-7, 2004, Bethesda, MD.
Sponsored by NIAAA, ORD, ODS, NCI, NIDA, NIDDK.
OTHER:
Presentations:
Departmental/Toxicology
1. Research in progress (1985-1999)
2. Mechanism of ethanol-induced pancreatitis (Toxicology group, 2001)
Biotransformation (inter- and intra-departmental group):
1.
2.
3.
4.
Characterization of Hepatic Fatty Acid Ethyl Ester Synthase, 2001
Inhibitors and Inducers of Fatty Acid Ethyl Ester Synthase, 2002
Mechanism of Alcoholic Pancreatitis, 2003.
Alcoholic Liver Disease: A Road from Fatty Liver to Cirrhosis, 2004
National
Kaphalia BS, and Ansari GAS. Trichloromethyl radical binding to microsomal lipids of rat liver in carbon
tetrachloride metabolism. Annual Meeting of Society of Toxicology, Atlanta, GA, Feb. 27-March 3, 1989,
Toxicologist 9: 25; 1989.
Kaphalia BS (Symposia speaker). Metabolic basis of alcoholic pancreatitis: Role of nonoxidative
metabolism. Alcoholic Pancreatitis. International Society of Biomedical Research on Alcohol. July 7-12,
2007. Chicago, IL.
International
Kaphalia BS, and Ansari GAS. Fatty acid ethyl esters and ethanol-induced pancreatic injury. World
Congress on Cellular and Molecular Biology. October 8-13, 2000. Jena, Germany. Cell. Mol Biol 46, 103,
2000.
Kaphalia, B.S.
Page 9
Kaphalia BS. Metabolic basis and mechanism(s) of alcoholic pancreatitis; what we have learned so far.
Invited speaker, Alcoholic Liver and Pancreatic Diseases Symposium. 8th International Symposium on
ALPD and Cirrhosis (ISALPD/C), sponsored by NIAAA, NIH, USA and ILBS, New Delhi, India, November
16-17, 2013
Chair or Co-chairperson of Scientific Sessions at National Meetings:
Platform session: Molecular Mechanisms of Oxidative Injury, 42nd Annual Meeting of Society of Toxicology,
Salt Lake City, Utah, March 9-13, 2003.
Poster session: Mechanisms of Phase I and Phase II Biotransformation. 43rd Annual Meeting of Society of
Toxicology, Baltimore, Maryland, March 21-24, 2004.
Poster session: Oxidative Stress, 44th Annual Meeting of Society of Toxicology, New Orleans, LA, March
6-10, 2005.
Poster session: In Vitro, 44th Annual Meeting of Society of Toxicology, New Orleans, LA, March 6-10, 2005.
Poster session: Disposition/Pharmacokinetics. 46rd Annual meeting of Society of Toxicology, Charlotte,
NC, March 25-29, 2007
Poster session: Inflammation: Methods and Mechanisms. 53rd Annual meeting of Society of Toxicology,
Phoenix, AZ, March 23-27, 2014 (will do).
INVITED LECTURES AT SYMPOSIA AND CONFERENCES:
Fatty Acid Ethyl Esters in Ethanol-Induced Pancreatitis, 3rd World Congress on Cellular and Molecular
Biology, Jena, Germany, Oct. 8-13, 2000.
Metabolic basis of ethanol-induced pancreatitis. Symposium: Mechanism of Alcoholic Pancreatitis,
sponsored by NIAAA and ORD/NID, Chicago, IL, Nov. 12-13, 2002.
Fatty acid conjugation: A toxic metabolic pathway in xenobiotic disposition. NIEHS Center seminar series.
UTMB, March 1, 2004.
Metabolic Basis of Alcoholic Pancreatitis: Role of Nonoxidative metabolism. Symposium: Mechanisms of
Alcoholic Pancreatitis. International Society of Biomedical Research on Alcohol (ISBRA), Chicago, IL, July
8, 2007.
Alcoholic Liver Disease: Mechanisms and Biomarkers. NIEHS Center Seminar Series, Dec. 14, 2009.
Metabolic Basis of Alcoholic Pancreatitis and its Early Biomarkers: Mini Symposium on Pancreatic
Disease, UTMB Sealy Center for Cancer Biology. January 12, 2012.
Metabolic basis and mechanism(s) of alcoholic pancreatitis; what we have learned so far. Invited speaker,
Alcoholic Liver and Pancreatic Diseases Symposium. 8th International Symposium on ALPD and Cirrhosis
(ISALPD/C), sponsored by NIAAA, NIH, USA and ILBS, New Delhi, India, November 16-17, 2013.
PRECEPTOR OF SUMMER RESEARCH PROGRAM:
1990
Edward Gonzales (Fatty acid conjugates of chlorinated phenols)
Kaphalia, B.S.
Page 10
1993
1994
1995
1996
1997
1999
2000
Helen Lucia, (HPLC separation of cholesterol chloroacetates)
Kendra Martin (Increased endobiotic methylation of fatty acids)
Sean Gallagher (Chemically-induced hemolytic anemia)
Steven K. Choa (Kinetics of in vivo formation of fatty acid anilides)
Steven K. Choa (Follow-up studies)
Keegan Autachi Duchicela (Analysis of plasma fatty acid ethyl esters)
Lakesha Demerson (Fatty acid ethyl esters in alcoholics)
COMMUNITY SERVICE:
1.
2.
3.
Judge: High School Science Fair (1993-1995).
Coach: Galveston Youth Soccer Club (1996 and 1997).
Coach: Galveston East Little Baseball League (1999).
A.
ARTICLES IN PEER-REVIEWED JOURNALS:
PUBLISHED:
1.
Singh S, Tripathi VK, Kaphalia BS, Seth TD. Residues of endosulfan in/on brinjal fruits. Progr Hort
13: 19-25, 1980.
2.
Kaphalia BS, Husain MM, Seth TD, Kumar A, Krishna-Murti CR. Organochlorine pesticide residues
in some Indian wild birds. Pest Monit J 15:9-13, 1981.
3.
Kaphalia, BS, Seth TD. DDT and BHC residues in some body tissues of goats, buffalo and
chickens. Pest Monit J 15: 103-106, 1981.
4.
Kaphalia, BS, Chandra H, Bhargava SK, Seth TD, Gupta BN. Lead in drinking water. Ind J Environ
Protect 1: 92-97, 1981.
Seth TD, Kaphalia BS. 1, 2, 3, 4, 5, 6-Hexachlorocyclohexane (HCH) residues in tissues of sheep.
Vet Human Toxicol 23: 247-248, 1981.
5.
6.
Kaphalia BS, Seth TD. Organochlorine pesticide contamination in some species of fodder
grasses. Environ Pollut 3: 231-237, 1982.
7.
Kaphalia BS, Seth TD. Chlorinated pesticide residues in blood plasma and adipose tissues of
normal and exposed human population, Ind J Med Res 77: 245-247, 1983.
8.
Seth TD, Kaphalia BS. Residue levels of DDT in the body tissues of sheep. J Environ Biol 4: 9597, 1983.
9.
Kaphalia BS, Seth TD. Screening of blood serum of food animals, chicken and human beings for
organochlorine pesticides and electrolytes. Ind J Anim Hlth 23: 23-27, 1984.
10.
Dikshith TSS, Raizada RB, Srivastiva MK, Kaphalia BS. Response of repeated oral administration
of endosulfan in rats. Indust Hlth 22: 295-306, 1984.
11.
Ramakrishnan, N, Kaphalia BS, Seth TD, Roy NK. Organochlorine pesticide contaminants in
mother’s milk; a source of toxic chemicals in suckling infants. Human Toxicol 4: 7-12, 1985.
12.
Kaphalia BS, Siddiqui FS, Seth TD. Contamination levels in different food items and dietary intake
of chlorinated pesticide residues in India. Ind J Med Res 81: 71-78, 1985.
Kaphalia, B.S.
Page 11
13.
Kaphalia BS, Seth TD. Chlorinated pesticide residues in human body tissues at autopsy.
Pesticides, 19: 18-19, 1985.
14.
Takroo R, Kaphalia BS, Seth TD. Chlorinated pesticide residues in different brands of butter. J
Food Sci Technol 22: 54-59, 1985.
15.
Kaphalia, BS, Nigam U, Mehrotra, S, Seth TD. Freshwater fish: An indicator of pesticide
contamination in the aquatic environment. J Environ Biol 7: 1-9, 1986.
16.
Kar AM, Seth TD, Kaphalia BS, Shukla R, Nag D. Pesticide contamination of HCH: A possible
factor for the altered levels of electrolytes and trace elements in the CSF of epileptic patients. Ind
J Med Sci 40: 1-5, 1986.
17.
Ansari, GAS, Kaphalia BS, Boor PJ. Selective pancreatic toxicity of palmitoylpentachlorophenol.
Toxicology 46: 57-63, 1987.
18.
Kaphalia, BS and Ansari GAS. 2-Chloroethylesterate: an in vivo fatty acid conjugate of 2chloroethanol. Bull Environ Contam Toxicol 39: 835-842, 1987.
19.
Tripathi UK, Kaphalia BS, Seth TD, Singh S. Composition of litchi cultivars. Indian Food Packer, 7:
7-10, 1987.
20.
Kaphalia BS, Bhargava SK, Nigam U, Seth TD. Levels of organochlorine pesticide residues in the
water samples collected from Srinagar (J&K), India. Ind J Environ Protect 8: 326-329, 1988.
21.
Kaphalia BS, Ansari GAS. Hepatic fatty acid conjugation of 2-chloroethanol and 2-bromoethanol in
rats. J Biochem Toxicol 4: 183-188, 1989.
22.
Kaphalia BS, Ansari, GAS. Covalent modification of hepatic microsomal lipids of rats by carbon
tetrachloride. Mol Toxicol 2: 199-213, 1989.
23.
Kaphalia, BS, Ansari GAS. Trichloromethyl peroxyl radical (Cl3C00.) mediated oxidation of
cholesterol. Chemosphere 20: 5-11, 1990.
24.
Kaphalia BS, Takroo R, Mehrotra S, Nigam U, and Seth TD. Organochlorine pesticide (OCP)
residues in different Indian cereals, spices, vegetables, fruits, milk, butter, deshighee and edible oils.
J Assoc Off Anal Chem 73: 509-512; 1990.
25.
Husain, MM, Kaphalia BS. Bioconcentration of cadmium, manganese and lead in some common
species of wild birds captured from a semipopulated area in the Indo-Gangetic Plains. J Environ
Biol 11: 193-201, 1990.
26.
Srivastava JS, Tripathi BM, Kaphalia, BS, Trivedi JK. Plasma amitryptiline levels and therapeutic
response in depressed patients. Ind J Psych 33: 16-19, 1991.
27.
Kaphalia BS. Fatty acid conjugates of chlorinated phenols: Synthesis, structural elucidation, and
high performance liquid chromatographic analysis. J Chromatogr 537: 85-92, 1991.
28.
Kaphalia BS, Ansari GAS. Rapid Chromatographic analysis of fatty acid anilides suspected of
causing toxic oil syndrome. J Anal Toxicol 14: 90-94, 1991.
29.
Khan MF, Kaphalia BS, Palafox A Jerrells, TR, Ansari GAS. Heated linoleic acid anilide: Toxicity
and relevance to toxic oil syndrome. Toxicology, 68: 143-155, 1991.
Kaphalia, B.S.
Page 12
30.
Khan MF, Kaphalia BS, Ansari GAS. Treated linoleic acid anilide reduces serum enzyme activities
in rats. Res Commun Chem Path Pharm 73: 107-110, 1991.
31.
Khan MF, Kaphalia BS, Palafox A, Jerrells TR, Ansari GAS. Toxicity of oleic acid anilide in rats.
Arch Environ Contam Toxicol 21: 571-577, 1991.
32.
Boor PJ, Khan MF, Kaphalia BS, Jerrells TR, Ansari GAS. Synergistic vascular toxicity and fatty
acid anilides in the toxic oil syndrome. J Am Coll Cardiol 18: 1824-1828, 1991.
33.
Kaphalia BS, Khan MF, Ansari GAS. Reduced activities of serum lactate dehydrogenase and
aminotransferases due to an oral administration of 2-chloroethyl linoleate in rats. Bull Environ
Contam Toxicol 48: 308-312, 1992.
34.
Kaphalia BS, Bhat HK, Khan MF, Ansari GAS. Tissue distribution of monochloroacetic acid and its
binding to albumin in rats. Toxicol Indust Hlth 8: 53-61, 1992.
35.
Kaphalia BS, Khan MF, Boor PJ, Ansari GAS. Toxic response to repeated oral administration of
2-chloroethyl linoleate in rats. Res Commun Chem Path Pharmacol. 76: 209-222, 1992.
36.
Khan MF, Kaphalia BS, Ansari GAS. Toxic response of linoleic acid anilide in female rats. Res
Commun Chem Pathol Pharmacol 77: 241-244, 1992.
37.
Kaphalia, BS, Ansari GAS. Covalent binding of ethylene dibromide and its metabolites to albumin.
Toxicol Lett 62: 221-230, 1992.
38.
Kanz MF, Kaphalia L, Kaphalia BS, Ramagnoli E, Ansari GAS. Methylene dianiline: Metabolism
and its effects on biliary functions. Toxicol Appl Pharmacol 117: 88-97, 1992.
39.
Khan MF, Kaphalia BS, Boor PJ, Ansari GAS. Subchronic toxicity of aniline hydrochloride in rats.
Arch Environ Contam Toxicol 24: 368-374, 1993.
40.
Ahmad, F, Kaphalia, BS, Khan, MF, Ansari, GAS. Fatty acid anilides: A new conjugation pathway
of aniline. Biochem Arch 9: 111-118, 1993.
41.
Khan MF, Boor PJ, Kaphalia BS, Alcock NW, Ansari GAS. Hematopoietic toxicity of linoleic acid
anilide: Importance of aniline. Fundam Appl Toxicol 25: 224-232, 1995.
42.
Khan MF, Kaphalia BS, Ansari GAS. Erythrocyte-aniline interaction leads to their accumulation
and iron deposition in rat spleen. J Toxicol Environ Hlth 44: 415-421, 1995.
43.
Ansari GAS, Kaphalia BS, Khan MF. Fatty acid conjugates of xenobiotics. Toxicol Lett 75: 1-17,
1995.
44.
Khan MF, Kaphalia BS, Prabhakar BS, Kanz MF, Ansari GAS. Trichloroethene-induced
autoimmune response in female MRL +/+ mice. Toxicol Appl Pharmacol 134: 155-160, 1995.
45.
Zeng FY, Kaphalia BS, Ansari GAS, Weigel PH. Fatty acylation of the rat asialoglycoprotein
receptor: The three subunits from active receptors contain covalently bound palmitate and stearate.
J Biol Chem 270: 21382-21387, 1995.
46.
Kapahlia BS, Carr JB, Ansari GAS. Increased endobiotic fatty acid methyl esters following
exposure to methanol. Fundam Appl Toxicol 28: 264-273, 1995.
Kaphalia, B.S.
Page 13
47.
Kaphalia BS, Khan MF, Carroll RM, Aronson J, Ansari GAS. Subchronic toxicity of 2-chloroethanol
and 2-bromoethanol in rats. Res Commun Pharmacol Toxicol 1:173-186, 1996.
48.
Kaphalia BS, Ghaneyam BJ, Ansari GAS. Nonoxidative metabolism of 2-butoxyethanol via fatty
acid conjugation in Fischer 344 rats. J Toxicol Environ Hlth 49: 101-117, 1996.
49.
Khan MF, Kaphalia BS, Ansari GAS. Time-dependent autoimmune response of dichloroacetyl
chloride in female MRL +/+ mice. Immunopharmacol Toxicol 19: 265-277, 1997.
50.
Kaphalia BS, Fritz RR, Ansari GAS. Purification and characterization of rat liver microsomal fatty
acid ethyl and 2-chloroethyl ester synthase and their relationship with carboxylesterase (pl 6.1).
Chem Res Toxicol 10: 211-218, 1997.
51.
Khan MF, Xiaohong W, Kaphalia BS, Boor PJ, Ansari GAS. Acute hematopoietic toxicity of aniline
in rats. Toxicol Lett 92: 31-37, 1997.
52.
Kaphalia BS, Ansari GAS. Single step thin-layer chromatographic method for quantitation of
enzymatic formation fatty acid anilides. J Chromatogr B. 705: 269-275, 1998.
53.
Hadjipavlou AG, Simmons JW, Young JP, Ansari GAS, Kaphalia BS, Simmons DJ, Nicodemus CL,
Lane R, Esch O. Torsional injury resulting in disc degeneration: an in vivo rabbit model. J Spinal
Disorder 11: 312-317, 1998.
54.
Kaphalia BS, Khan MF, Ansari GAS. Fatty acid anilides: In vivo formation and relevance to Toxic
Oil Syndrome. J Biochem Mol Toxicol 13: 269-277, 1999.
55.
Kaphalia BS, Green SG, Ansari GAS. Fatty acid ethyl and methyl ester synthases, and fatty acid
anilide synthase in HepG2 and AR42J cells: interrelationships and inhibition by tri-o-tolyl phosphate.
Toxicol Appl Pharmacol 159: 134-141, 1999.
56.
Green SM, Khan MF, Kaphalia BS, Ansari GAS.
Immunohistochemical localization of
trichloroacylated protein adducts in tetrachloroethene-treated rats. J. Toxicol. Environ. Hlth. 63:
145-147, 2001.
57.
Kaphalia BS, Ansari GAS. Purification and characterization of rat hepatic microsomal low
molecular weight ethyl ester synthase and their relationship to carboxylesterases. J Biochem Mol
Toxicol. 15: 165-171, 2001.
58.
Kaphalia BS, Khan MF, Green SM, Mericle KA, Ansari GAS Xenobiotic conjugates of fatty acids.
Pharmacology and Therapeutics in the New Millennium. pp 698-706, 2001.
59.
Kaphalia BS, Ansari GAS. Fatty acid ethyl esters and ethanol-induced pancreatitis. Cell. Mol. Biol.
47: OL173-OL179, 2001.
60.
Mericle KA, Kaphalia BS, Ansari GAS. Differential inhibition of hepatic, pancreatic, and plasma fatty
acid ethyl ester synthase by tri-O-tolylphosphate in rats. Toxicol. Appl. Pharmacol. 179: 119-125,
2002.
61.
Kaphalia BS, Ansari GAS. Purification and characterization of rat pancreatic fatty acid ethyl ester
synthase and its structural and functional relationship to pancreatic cholesterol esterase. J Biochem
Mol Toxicol. 17: 338-245, 2003.
Kaphalia, B.S.
Page 14
62.
Khan MF, Wu X, Kaphalia BS, Boor PJ, Ansari GAS. Nitrotyrosine formation in spelenic toxicity of
aniline. Toxicology 194: 95-102, 2003.
63.
Mericle KA, Kaphalia BS, Ansari GAS. Modulation of fatty acid methyl esters in rats pretreated with
tri-O-tolyl phosphate. J. Toxicol. Environ. Hlth. Part A, 67: 583-593, 2004.
64.
Li H, Kaphalia BS, Ansari GAS, Khan MF. Quantitation of acrolein-protein adducts: potential
biomarkers of acrolein exposure. J. Toxicol. Environ. Hlth. Part A, 67: 513-524, 2004.
65.
Kaphalia BS, Mericle KA, Ansari GAS. Mechanism of Differential Inhibition of Hepatic and
Pancreatic Fatty Acid Ethyl Ester Synthase by Inhibitors of Serine-Esterases: In Vitro and Cell
Culture Studies. Toxicol. Appl. Pharmacol. 200: 7-15, 2004.
66.
Kaphalia BS, Ping Cai, Khan MF, Okorodudu AO, Ansari GAS. Fatty acid ethyl esters in alcoholics;
markers of alcohol abuse and alcoholism. Alcohol 34: 151-158, 2004.
67.
Khan SH, Kaphalia BS, Ansari GAS. In vivo conjugation of ethanolamine with fatty acids by rat liver
subcellular fractions. J Toxicol Environ Health, part A 68: 667-576, 2005.
68.
Cai P, Kaphalia BS, Ansari GAS. Methyl palmitate: Inhibitor of phagpcytosis in rat primary Kupffer
cells. Toxicololgy 219, 197-204, 2005.
69.
Liu T, Zaman W, Kaphalia BS, Ansari S, Garofalo RP, Casola A. RSV-induced prostaglandin
production occurs via cPLA2 activation: role in viral replication. Virology 343: 12-24, 2005.
70.
Cai P, Khan F, Kaphalia BS, Ansari GAS. Immunotoxic response of oleic acid anilide and its
hydrolysis products in female MRL+/+ mice. J. Immunotoxicol. 2: 231-236, 2005.
71.
Kaphalia L, Kaphalia BS, Kanz MF and Moslen MT. Efficient high pressure liquid
chromatograph/UVmethod for detection of Diclofenac and 4-OH-diclofenac in serum.
J
Chromatogr. B 830: 231-237, 2006.
72.
Sam J, Kaphalia BS, *Nissi J, Ahmed EA. The water disinfectant byproduct dibromoacetonitrile
induces apoptosis in rat intestinal epithelial cells: possible role of redox imbalance. Toxicol Mech
Meth 16: 227-234, 2006.
73.
Wu H, Cai P, Clemens DL, Jerrells TR, Ansari, GAS, Kaphalia BS. Metabolic basis of ethanolinduced cytotoxicity in stable and recombinant HepG2 cells: Role of nonoxidative metabolism.
Toxicol. Appl. Pharmacol. 216: 238-247, 2006.
74.
Ping Cai, Konig R, Khan MF, Qiu S, Kaphalia, BS, Ansari, GAS. Autoimmune response in MRL
+/+ mice following treatment with dichloroacetyl chloride or dichloroacetic anhydride. Toxicol. Appl.
Pharmacol. 216: 248-255, 2006.
75.
Bhopale K, Wu H, Boor PJ, Popav, VL, Ansari GAS, Kaphalia BS. Metabolic basis of ethanolinduced hepatic and pancreatic toxicity in hepatic alcohol dehydrogenase-deficient deer mice.
Alcohol 39: 179-188, 2006.
76.
Sarkar S, Khan MF, Kaphalia BS, Ansari GAS. Methyl palmitate Inhibits lipopolysccharidestimulated phagocytic activity of rat peritoneal macrophages. J Biochem. Mol. Toxicol. 20: 302-308,
2006.
77.
Cai P., Konig R, Khan MF, Kaphalia, BS, Ansari, GAS Differential immune responses to albumin
Kaphalia, B.S.
Page 15
adducts of reactive intermediates of trichloroethene in MRL +/+ mice Toxicology and Applied
Pharmacology 220: 278-83, 2007.
78.
Cai P., Boor PJ, Khan MF, Kaphalia, BS, Ansari GAS, Konig R. Immuno- and hepato-toxicity of
dichloroacetic acid in MRL+/+ and B6C3F1 mice. J Immunotoxicology 4: 107-115, 2007.
79.
Wu H, Bhopale K, Ansari GAS, Kaphalia BS. Ethanol-induced cytotoxicity in rat pancreatic acinar
AR42J cells: Role of fatty acid ethyl esters. Alcohol Alcoholism 43: 1-8, 2008.
80.
Cai P, König R, Boor PJ, Kondraganti S, Kaphalia BS, Khan MF, Ansari GA. Chronic exposure to
trichloroethene causes early onset of SLE-like disease in female MRL +/+ mice. Toxicol Appl
Pharmacol. 228: 68-75, 2008.
81.
Jeng YJ, Nauduri D, Kaphalia BS, Watson CS Effects of coumestrol, daidzein genistein,
resveratrol, and diethylstilbestrol on serum prolactin levels and the induction of pituitary tumors in
Fischer 344 rats. J Nutri. Metabol. 7: 40-53, 2010.
82.
Kaphalia BS, Bhopale KK, Kondragunti S, Wu H, Boor PJ, Ansari GAS. Ethanol-Induced Pancreatic
Injury and Endoplasmic Reticulum Stress in Hepatic Alcohol-Dehydrogenase-Deficient Deer Mice.
Toxicol Appl Pharmacol. 246: 154-162, 2010.
83.
Fernando H, Kondraganti S, Bhopale KK, Neerathilingam M, Volk DE, Kaphalia BS, Luxon B A,
Boor PJ, Ansari G A S. 1H and 31P NMR Lipidome of Ethanol-Induced Fatty Liver. Alcoholism: Clin.
Exp. Res. 34: 1937-1947, 2010.
84.
Fernando H, Kondraganti S, Bhopale KK, Kondraganti S, Kaphalia BS, Ansari G A S. Lipidomic
changes in rat liver after long term exposure to ethanol. Toxicol Appl Pharmacol. 255: 127-137,
2011.
85.
Bhopale K.K , Nauduri D, Soman KV, Sood GK, Okorodudu A, Ansari GAS, Kaphalia BS.
Differentially altered plasma proteins in patients diagnosed with alcoholic liver disease and
nonalcoholic steatohepatitis. Euroasian J. Hepato-Gastroenterology 1, 89-99, 2011.
86.
Fernando H, Bhopale KK, Boor PJ, Ansari GAS, Kaphalia BS. Hepatic lipid profiling of deer mice
fed ethanol using 1H and 31P NMR spectroscopy: A dose-dependent subchronic study. Toxicol
Appl Pharmacol. 264, 361-369, 2012.
87.
Kondraganti S, König R, Boor PJ, Khan S, Kaphalia BS, Khan MF, Ansari GAS. Mechanistic
evaluation of trichloroethene-mediated autoimmune hepatitis-like disease in female MRL+/+ mice.
The Open Toxicol. J. 5: 1-10, 2012.
88.
Fernando H, Wiktorowicz JE, Soman KV, Kaphalia BS, M. Firoze Khan, Ansari GAS. Liver
proteomics in progressive alcoholic steatosis. Toxicol Appl Pharmacol. 266, 470-480, 2013.
89.
Bhopale KK, Falzon M, Ansari GAS, Kaphalia BS. Metabolic basis of ethanol-induced pancreatic
acinar cell toxicity in AR42J cells. In Vitro Cellular & Developmental Biology 50, 373-380, 2014.
90.
Booth DM, Haung W, Cane MC, Mukherjee R, Kaphalia BS, Peterson OH, Tepikin AV, Jaffar M,
Sutton R and Criddle DN. Fatty acid ethyl ester synthase inhibition ameliorates ethanol-induced
Ca+-dependent mitochondrial dysfunction and acute pancreatitis. Gut 63, 1313-1324, 2014.
91.
Kaphalia L, Boroumand N, Hyunsu J, Kaphalia BS* (corresponding author), Calhoun WJ. Ethanol
metabolism, oxidative stress, and endoplasmic reticulum stress responses in the lungs of hepatic
Kaphalia, B.S.
Page 16
alcohol dehydrogenase deficient deer mice after chronic ethanol feeding. Toxicol Appl Pharmacol.
277, 109-117, 2014.
IN PRESS/SUBMITTED:
B.
OTHER:
Thesis title: Physical and chemical changes in mammalian red blood cells induced by 1,2,3,4,5,6hexachlorocyclohexane (HCH); Chemistry Department, University of Kumaun, Nainital, U.P., 1984.
Book Chapters
1.
Ansari GAS, Kaphalia BS, Boor PJ. Palmitoylpentachlorophenol: Formation and toxicity.
Proceedings of International Conference on Biomembranes in Health and Disease, Kidwai AM,
Upreti RK, Ray PK. (Eds.). Nov. 1-4, 1988, Lucknow, India. 1: 217-224, 1991.
2.
Kaphalia, BS. Pancreatic Toxicology In: Nriagu JO (ed.) Encyclopedia of Environmental Health,
volume 4, pp. 315–324 Burlington: Elsevier, 2011.
3.
Kaphalia BS, Biomarkers of Acute and Chronic Pancreatitis in “Biomarkers in Toxicology” (eds.
Gupta RC, Chapter-16, pp 279-289, Academic Press/Elsevier, 2014).
Invited reviewer for ATSDR/EPA Toxicological Profiles/Monographs:
Provisional Toxicological Values for the Health Effects Assessment Summary Table (HEAST):
Diethylene Glycol Monobutyl Ether (CASRN 112-34-5). 2003
Provisional Toxicological Values for the Health Effects Assessment Summary Table (HEAST):
Diethylene Glycol Monoethyl Ether (CASRN 111-90-0). 2003
Toxicological Profile for 1,1,1-Trichloroethane; Department of Health and Human Services, Public
Health Service and Agency for Toxic Substances and Disease Registry, Division of
Toxicology/Toxicology Information Branch, Atlanta, GA.; U.S., 2004.
Agency for Toxic Substances and Disease Registry’s Toxicological Profile on Diazinon, 2006.
Provisional Peer Reviewed Toxicity Values for Chloroethane; Superfund Health Risk Technical
Support Center, National Center for Environmental Assessment, Office of Research and
Development, U.S. EPA, Cincinnati, OH. 2006.
EPA’s draft Provisional Peer Reviewed Toxicity Values (PPRTV) Manuscript for Chloroethane
Developed for Superfund Health Risk Technical Support Center (STSC), 2006.
C.
ABSTRACTS:
1.
Kaphalia BS, Seth TD. DDT and BHC residue levels in human body tissues and food materials.
Society of Toxicology, Industr. Toxicol. Res. Centre, Lucknow, India; 1979.
2.
Kaphalia BS, Husain MM, Kumar A, Seth TD, Krishnamurti CR. Organochlorine pesticide residues
in some Indian wild birds. Second Congress of the Federation of Asian & Oceanian Biochemists &
Golden Jubilee Annual Meeting of the Society of Biological Chemists, India. Indian Institute of
Science, Bangalore, India; 1980.
Kaphalia, B.S.
Page 17
3.
Ramakrishnan N, Kaphalia BS, Seth TD, and Roy NK. Pesticide residue levels in human milk in
India. Annual Meeting of Society of Toxicology, Industrial Toxicology Research Centre, India; 1981.
4.
Kaphalia BS, Das B, Kannan K. Role of glutathione in endosulfan toxicity. Annual Meeting of
Society of Biological Chemists, Lucknow, India; 1983.
5.
Kaphalia BS, Ansari GAS. Covalent binding of 14C-CCl4 to neutral lipids. Annual Meeting of Society
of Toxicology, New Orleans, LA, March 3-7, 1986, Toxicologist 6: 152, 1986.
6.
Kaphalia BS, Ansari GAS. Covalent binding of [14C]-CCl4 metabolites with phospholipids of hepatic
microsomes from phenobarbital treated rats. Annual Meeting of Society of Toxicology, Washington,
DC, Feb. 24-27, 1987, Toxicologist 7: 267, 1987.
7.
Ansari GAS, Kaphalia BS, Sunio D, Gan JC. Covalent binding of [14C]-ethylene dibromide with
albumin. Annual Meeting of Society of Toxicology, Dallas, TX, Feb.15-19, 1988, Toxicologist 8: 187,
1988.
8.
Kaphalia BS, Ansari GAS. 2-Chlorethylsterate: An in vivo fatty acid conjugate of 2-chloroethanol.
Annual Meeting of Society of Toxicology, Dallas, TX, Feb. 15-19, 1988, Toxicologist 8: 187, 1988.
9.
Kaphalia BS, Ansari GAS. In vivo conjugation of 2-bromoethanol with the microsomal fatty acids of
rat liver. Federation of American Society of Experimental Biology, Las Vegas, NV, May 1-5, 1988,
FASEB J 2:A373, 1988.
10.
Ansari GAS, Kaphalia BS, Boor PJ. Palmitoylpentachlorophenol: Formation and toxicity.
International Conference in Biomembranes in Health and Disease. Industrial Toxicology Research
Centre, Lucknow, India, November 1-4, 1988.
11.
Kaphalia BS, Ansari GAS. Trichloromethyl radical binding to microsomal lipids of rat liver in carbon
tetrachloride metabolism. Annual Meeting of Society of Toxicology, Atlanta, GA, Feb. 27-March 3,
1989, Toxicologist 9: 25, 1989.
12.
Ansari GAS, Bhat HK, Kaphalia BS. In vitro formation of fatty acid conjugates of 2-chloro- and 2bromoethanols and role of cholesterol ester hydrolase. V International Congress of Toxicology, July
16-21, Brighton, England, 1989.
13.
Kaphalia BS, and Ansari GAS. Toxicokinetics and metabolism of palmitoylpentachloro- phenol in
rats. Annual Meeting of Society of Toxicology, Miami, FL, Feb. 12-16, 1990, Toxicologist 10: 218;
1990.
14.
Kaphalia BS. Fatty acid conjugates of chlorinated phenols: Synthesis, structural elucidation and
high performance liquid chromatography. Federation of American Society of Experimental Biology,
Washington, DC, April 1-5, 1990.
15.
Khan MF, Kaphalia BS, Ansari GAS. Biochemical alterations in rats treated with oleic acid anilide.
1990 Annual Meeting of Gulf Coast Chapter of Society of Toxicology, Austin, TX, Nov. 15-17, 1990.
16.
Khan MF, Kaphalia BS, Palafox A, Jerrells TR, Ansari GAS. Heated linoleic acid anilide: Toxicity
and relevance to toxic oil syndrome. Annual Meeting of Society of Toxicology, Dallas, TX, Feb. 25March 1, 1991, Toxicologist 11: 326, 1991.
17.
Kaphalia BS, Khan MF, Carroll RM, Ansari GAS. Subchronic toxicity of 2-chloro- ethanol and 2bromoethanol in rats. Annual Meeting of Society of Toxicology, Dallas, TX, Feb. 25-March 1, 1991,
Kaphalia, B.S.
Page 18
Toxicologist 11: 320, 1991.
18.
Ansari GAS, Kaphalia L, Kaphalia BS, Romagnoli E, Mohsin S, Kanz MF. Methylene dianiline:
Toxicity, metabolism and effects on biliary function. Annual Meeting of Society of Toxicology, Dallas,
TX, Feb. 25-March 1, 1991, Toxicologist 11: 170, 1991.
19.
Kaphalia BS, Khan MF, Palafox A, Jerrells TR, Ansari GAS. Biochemical and immunological studies
of fatty acid anilides in rotation of toxic oil syndrome. Federation of American Society of Experimental
Biology, Atlanta, GA., April 21-25, 1991, FASEB J. 5: A553; 1991.
20.
Kaphalia BS, Khan MF, Boor PJ, Ansari GAS. Toxicity evaluation of 2-chloroethyl linoleate in rats.
Annual Meeting of Society of Toxicology, Seattle, WA, Feb. 22-29, 1991, Toxicologist 12:145, 1992.
21.
Khan MF, Kaphalia BS, Ansari GAS. Toxic response to linoleic acid anilide in female rats in relation
to Toxic Oil Syndrome. Annual Meeting of Society of Toxicology, Seattle, WA, Feb. 22-29, 1992,
Toxicologist 12: 42, 1992.
22.
Khan MF, Kaphalia BS, Boor PJ, Ansari GAS. Subchronic toxicity of aniline hydrochloride in rats.
Federation of American Society of Experimental Biology, Anaheim, CA, April 6-10, 1992, FASEB J.
6: A1913, 1992.
23.
Khan MF, Kaphalia BS, Ansari GAS. The hemopoietic system as an early target of linoleic acid
anilide toxicity. Toxicology Letters (Suppl.) pp 295, 1992.
24.
Khan MF, Kaphalia BS, Ansari GAS. In vivo toxicity of linoleic acid anilide and its hydrolysis
products. Annual Meeting of Society of Toxicology, New Orleans, LA., March 14-18, 1993,
Toxicologist 13: 424, 1993.
25.
Kaphalia BS, Bhat HK, Ansari GAS. Subcellular distribution and purification of enzyme responsible
for fatty acid haloethyl ester synthase activity. Annual Meeting of Society of Toxicology. Dallas, TX.
March 13-17, 1994.
26.
Khan MF, Boor PJ, Kaphalia BS, Ansari GAS. Splenic toxicity of linoleic acid anilide and its
hydrolysis products: Evidence of iron overload. Annual Meeting of Society of Toxicology, Dallas,
TX, March 13-17, Toxicologist 14:371, 1994.
27.
Green SM, Kanz MF, Khan MF, Kaphalia BS, Ansari GAS. Morphological changes in tissue from
MRL +/+ mice due to trichloroethene and dichloroacetyl chloride treatment. Annual Meeting of Gulf
Coast Chapter-Society of Toxicology, University of Texas Health Science Center at San Antonio, TX,
Nov. 2-4, Toxicologist 14:396, 1995.
28.
Havel TM, Kaphalia BS, Khan MF, Ansari GAS. In vivo formation of fatty acid anilides. Annual
Meeting of Gulf Coast Chapter Society of Toxicology, University of Texas Health Science Center at
San Antonio, TX, Nov. 2-4, 1995.
29.
Khan MF, Kanz MF, Kaphalia BS, Ansari GAS. Trichloroethylene-induced autoimmune response in
female MRL +/+ mice. Annual Meeting of Society of Toxicology, Baltimore, MD, March 5-9,
Toxicologist 15:228, 1995.
30.
Kaphalia BS, Carr JB, Ansari GAS. In Vivo esterification of fatty acids by methanol. Annual Meeting
of Society of Toxicology, Baltimore, MD, March 5-9, Toxicologist 15:102, 1995.
31.
Green SM, Kanz MF, Khan MF, Kaphalia BS, Ansari GAS. Morphological changes in tissues from
Kaphalia, B.S.
Page 19
MRL +/+ mice due to trichloroethylene dichloro- acetylchloride treatment. Annual Meeting of Society
of Toxicology, Anaheim, CA. March 10-14. Fundam Appl Toxicol 30:293; 1996.
32.
Kaphalia BS, Ghanayem BI, Ansari GAS. Non-oxidative metabolism of 2-butokyethanol via fatty
acid conjugation in Fischer 344 rats. Annual Meeting of Society of Toxicology, Anaheim, CA., March
10-14, 1996. Fundam Appl Toxicol 30:315; 1996.
33.
Khan MF, Kaphalia BS, Ansari GAS. Time-dependent autoimmune response of dichloroacetyl
-17, FACEB
J. A167; 1996.
34.
Kaphalia BS, Green SM, Ansari GAS. Differential expression of fatty acid ethylester synthase in
HepG2 and AR42J cells. 214th Annual Meeting of American Chemical Society (National), Las
Vegas, Nevada, Sept. 7-11, 1997.
35.
Kaphalia BS, Green SM, Santa Cruz V, Ansari GAS. Differential inhibition of hepatic and pancreatic
fatty acid ethyl ester synthase by tri-o-tolyl phosphate. Annual Meeting of Society of Toxicology,
Cincinnati, OH. March 9-13, 1997. Fundam Appl Toxicol 36:325; 1997.
36.
Green SM, Khan MF, Kaphalia BS, Ansari GAS. In vivo binding of tetrachloroethene with plasma
proteins. Annual Meeting of Society of Toxicology, Seattle, WA. March 1-5, 1998. The Toxicologist
42:131, 1998.
37.
Kaphalia BS, Khan MF, Ansari GAS. Biosynthesis of fatty acid anilides in tissues of rats and HepG2
cells following aniline exposure. Annual Meeting of Society of Toxicology, Seattle, WA, March 1-5,
1998. The Toxicologist 42:284, 1998.
38.
Daiker DH, Ward JB, Dugas TR, Kaphalia BS, Moslen MT. Characterization of a two detector HPLC
method for measuring benzene metabolites. Annual Meeting of Gulf Coast Chapter Society of
Toxicology, Galveston, TX, Nov. 7-8, p40, 1998.
39.
Kaphalia L, Kaphalia BS, Moslen MT. Why does Toxicant-induced bile canalicular injury decrease
total biliary protein yet increase biliary level of albumin and canalicular localized enzyme.
Gasteroenterology Poster Session, UTMB, Galveston, TX. 1998.
40.
Kaphalia BS, Green SG, Ansari GAS. Interrelationships among fatty acid ethyl and methyl ester
synthases and fatty acid anilide synthase in HepG2 and Ar42J cells. Annual meeting of Society of
Toxicology, New Orleans, LA. March 1-4, 1999. The Toxicologist 48: 225, 1999.
41.
Kaphalia BS, Khan MF, Green SM, Mericle KA, Ansari GAS. Fatty acid conjugates of xenobiotics.
International Congress of Frontiers in Pharmacology and Therapeutics in 21st Century, New Delhi,
India, December 1-4, 1999.
42.
Green SM, Khan MF, Kaphalia BS, Ansari GAS. Immunochemical detection of trichloroacylated
proteins in tetrachloroethene-treated autoimmune-prone mice. Annual meeting of Society of
Toxicology, Philadelphia, PA. March 19-23, 2000. The Toxicologist 54: 74, 2000.
43.
Mericle KA, Kaphalia BS, Ansari GAS. Dose-dependent effect of tri-O-tolyl phosphate on hepatic
and pancreatic fatty acid ethyl ester and methyl ester synthasizing activities. Annual meeting of
Society of Toxicology, Philadelphia, PA. March 19-23, 2000. The Toxicologist 54: 373, 2000.
44.
Kaphalia BS, Leslie V, Ansari GAS. Purification and characterization of rat pancreatic fatty acid
ethyl ester synthase and its relationship to fatty acid methyl esters and anilide synthesizing activities.
Kaphalia, B.S.
Page 20
Annual meeting of Society of Toxicology, Philadelphia, PA. March 19-23, 2000. The Toxicologist 54:
373, 2000.
45.
Kaphalia BS, Ansari GAS. Fatty acid ethyl esters and ethanol-induced pancreatic injury. World
Congress on Cellular and Molecular Biology. October 8-13, 2000. Jena, Germany. Cell. Mol Biol 46,
103, 2000.
46.
Kaphalia BS, Okorodudu, A, Ansari GAS. Plasma fatty acid ethyl esters and blood alcohol
concentration in alcoholics. Annual meeting of Society of Toxicology, San Francisco, CA, March 2529, 2001. The Toxicologist 60: 89, 2001.
47.
Kaphalia BS, Ansari GAS. Mechanism(s) of differential inhibition of hepatic and pancreatic fatty acid
ethyl esters synthase by inhibitors of beta-esterases. Annual meeting of Society of Toxicology,
Nashville, TN, March 17-21, 2002.The Toxicologist 66: 228, 2002.
48.
Mericle KA, Kaphalia BS, Ansari GAS. Inhibition of fatty acid ethyl ester synthase activity by tri-Otolylphosphate metabolites in HepG2 cells and AR42J cells. Symposium: Mechanism of Alcoholic
Pancreatitis, sponsored by NIAAA and ORD/NID, Chicago, IL, Nov. 12-13, 2002.
49.
Kaphalia BS, Ansari GAS. Metabolic basis of ethanol-induced pancreatitis. Symposium: Mechanism
of Alcoholic Pancreatitis, sponsored by NIAAA and ORD/NID, Chicago, IL, Nov. 12-13, 2002.
50.
Mericle KA, Kaphalia BS, Ansari GAS. Inhibition of fatty acid ethyl ester synthase activity by tri-Otolylphosphate metabolites in HepG2 cells. Annual meeting of Society of Toxicology, Nashville, TN,
March 17-21, 2002.The Toxicologist 66: 245, 2002.
51.
Kaphalia BS, Mericle KA, Ansari GAS. Mechanism(s) of differential inhibition of hepatic and
pancreatic fatty acid ethyl ester synthase activity by tri-O-tolyl phosphate metabolites. Annual
meeting of Society of Toxicology, Salt Lake City, Utah, March 9-13, 2003.The Toxicologist 72: 314,
2003.
52.
Mericle KA, Kaphalia BS, Ansari GAS. Modulation of fatty acid methyl ester formation in rats using
tri-O-tolyl phosphate. Annual meeting of Society of Toxicology, Salt Lake City, Utah, March 9-13,
2003.The Toxicologist 72: 315, 2003.
53.
Wu H, Khan MF, Clemens DL, Jerrells, TR, Ansari GAS, Kaphalia BS. Non-oxidative metabolism of
ethanol in HepG2 cells: contribution of alcohol dehydrogenase and cytochrome P450 2E1. Division
of Chemical Toxicology, Abstract # 89, 226th ACS National Meeting New York, NY, Sept. 7-11, 2003.
54.
Li H, Kaphalia BS, Ansari GAS, Khan MF. Biomarkers of acrolein exposure: compatatitive ELISA for
the quantitation of acrolein-protein adducts. Division of Chemical Toxicology, Abstract #49, 226th ACS
National Meeting New York, NY, Sept. 7-11, 2003.
55.
Cai P, Kaphalia BS, Ansari GAS. Palmitic acid methyl ester: Inhibitor of phagocytosis in primary rat
Kupffer cells. Department of Pathology Research Day. Tuesday May 13, 2003.
56.
Kaphalia BS, Wu H, Clemens DL, Jerrells, TR, Khan MF, Ansari GAS, Comparative biosynthesis of
fatty acid ethyl esters in AR42J cells and HepG2 cells. 43rd Annual meeting of Society of Toxicology,
Baltimore, Maryland, March 21-25, 2004. The Toxicologist 78, 301, 2004.
57.
Khan SH, Kaphalia BS, Ansari GAS. In vitro formation of ethanolamine conjugates with fatty acids.
43rd Annual meeting of Society of Toxicology, Baltimore, Maryland, March 21-25, 2004. The
Toxicologist 78, 300, 2004.
Kaphalia, B.S.
Page 21
58.
Wang J, Li H, Kannan S, Kaphalia BS, Khan MF. Overexpression of cytokines in splenic fibrogenic
response to aniline. 43rd Annual meeting of Society of Toxicology, Baltimore, Maryland, March 2125, 2004. The Toxicologist 78, 308, 2004.
59.
Cai P, Kaphalia BS, Ansari GAS. Inhibition of phagocytosis in primary rat Kupffer cells by methyl
palmitate. 43rd Annual meeting of Society of Toxicology, Baltimore, Maryland, March 21-25, 2004.
The Toxicologist 78, 310, 2004.
60.
Khan SH, Kaphalia BS, Ansari GAS. Endogenous fatty acid methyl esters as potential markers of
human hepatocellular carcinoma. 44th Annual meeting of Society of Toxicology, New Orleans,
Louisiana, March 6-10, 2005. The Toxicologist 84 (S-1), 17, 2005.
61.
Ansari GAS, Cai P, Khan MF, Kaphalia BS. Immunotoxicity of dichloroacetyl chloride and
dichloroacetic acid anhydride in female MRL +/+ mice. 44rd Annual meeting of Society of Toxicology,
New Orleans, Louisiana, March 6-10, 2005. The Toxicologist 84 (S-1), 186-187, 2005.
62.
Cai P, Khan MF, Kaphalia BS, Ansari GAS. Immunotoxicity of oleic acid anilide and its hydrolysis
products in MRL +/+ mice. 44th Annual meeting of Society of Toxicology, New Orleans, Louisiana,
March 6-10, 2005. The Toxicologist 84 (S-1), 187, 2005.
63.
Bhopale K, Wu H, Boor PJ, Popav, VL, Ansari GAS, Kaphalia BS. Pancreatic and hepatic ethanol
toxicity in hepatic alcohol dehydrogenase deficient deer mice: morphological and biochemical
characterization. 44th Annual meeting of Society of Toxicology, New Orleans, Louisiana, March 6-10,
2005. The Toxicologist 84 (S-1), 318, 2005.
64.
Wu H, Bhopale K, Ansari GAS, Kaphalia BS. Ethanol-induced toxicity and apoptosis in HepG2 cells
and VA-13 cells: role of acid ethyl esters. 44th Annual meeting of Society of Toxicology, New Orleans,
Louisiana, March 6-10, 2005. The Toxicologist 84 (S-1), 332, 2005.
65.
Kaphalia BS. Metabolism of ethanol in ADH-deficient HepG2 cells and ADH-Overexpressing VA-13
cells: Significance of non-oxidative metabolism in ethanol-induced toxicity. 45th Annual meeting of
Society of Toxicology, San Diego, CA, March 5-9, 691, 2006.
66.
Wu H, Ansari GAS, Kaphalia BS. Non-oxidaitve metabolism of ethanol to fatty acid ethyl esters and
their cytotoxicity. 45th Annual meeting of Society of Toxicology, San Diego, CA, March 5-9, 692,
2006.
67.
Cai P, Kaphalia BS, Ansari GAS. Immuno and hepatotoxicity of dichloroacetic acid in MRL+/+ mice.
45th Annual meeting of Society of Toxicology, San Diego, CA, March 5-9, 287, 2006.
68.
Sarkar S, Khan MF, Kaphalia BS, Ansari GAS. Inhibition of lipopolysccharide stimulated phagocytic
activity of rat peritoneal macrophages by methyl palmitate. 45th Annual meeting of Society of
Toxicology, San Diego, CA, March 5-9, 1720, 2006.
69.
Kaphalia BS. Dose-dependent metabolism of ethanol and related pancreatic injury in hepatic alcohol
dehydrogenase-deficient deer mice: significance of fatty acid ethyl esters. 46th Annual meeting of
Society of Toxicology, Charlotte, NC, March 25-29, 2007.
70.
Bhopale KK, Wu H, Ansari GAS, Kaphalia BS. Dose-dependent pancreatic and hepatic injury in
hepatic alcohol-dehydrogenase-deficient deer mice. 46th Annual meeting of Society of Toxicology,
Charlotte, NC, March 25-29, 2007.
Kaphalia, B.S.
Page 22
71.
Kaphalia BS. Metabolic Basis of Alcoholic Pancreatitis: Role of Non-oxidative metabolism.
Symposium: Mechanisms of Alcoholic Pancreatitis. July 8, 2007. International Society of Biomedical
Research on Alcohol (ISBRA), Chicago, IL.
72.
Bhopale KK, Soman, V., Sood, G.K., Okorodudu, AO, Wu H, Ansari GAS, Kaphalia BS.
Identification of biomarkers in alcoholic liver disease and nonalcoholic steatohepatitis: Protein
expression studies. 47th Annual meeting of Society of Toxicology, Seattle, WA, March 16-20, 2008.
73.
Kondraganti S, Boor, PJ, Konig R, Khan MF, Kaphalia BS, Ansari GAS. Apoptosis precedes multiorgan inflammation in MRL+/+ mice chronically exposed to TCE. 47th Annual meeting of Society of
Toxicology, Seattle, WA, March 16-20, 2008.
74.
Kondraganti S, Boor PJ, Khan FM, Konig R, Kaphalia BS, Ansari GAS. Copmpromised Kupffer cells
could lead TCE-mediated SLE-like disease. 47th Annual meeting of Society of Toxicology, Baltimore,
MD, March 15-29, 2008.
75.
Fernando H, Kondraganti S, Bhopale KK, Neerathilingam M, Volk DE, Kaphalia BS, Luxon B A,
Boor PJ, Ansari G A S. Lipidomics of alcohol-induced fatty liver. 49th Annual meeting of Society of
Toxicology, Baltimore, MD, March 15-19, 2009.
76.
Bhopale KK, Ansari GAS, Kaphalia BS. Ethanol metabolism and related cytotoxicity in AR42J cells.
48th Annual meeting of Society of Toxicology, Baltimore, MD, March 15-19, 2009.
77.
Kaphalia BS, Kondraganti S, Bhopale KK, Ansari GAS. Activation of endoplasmic reticulum-stress
in hepatic alcohol-dehydrogenase-deficient deer mice is associated with non-oxidative metabolism
of ethanol. 48th Annual meeting of Society of Toxicology, Baltimore, MD, March 15-19, 2009.
78.
Midoro-Horiuti T, Lin y, Nauduri D, Kaphalia BS, Goldblum R.M. Prenatal exposure of Bisphenol A
(BPA) enhances allergic sensitization. Annual Meeting of American Association of Allergy, Asthma
& Immunology. March 13-17, 2009. J. Allergy Clin Immunol. 123, S14, 2009.
79.
Bhopale KK, Soman KV, Ansari, GAS, Kaphalia BS. Differential expression of proteins in the livers
of hepatic alcohol dehydrogenase–deficient deer mice after subchronic exposure of ethanol. 49th
Annual meeting of Society of Toxicology, Salt Lake City, Utah, March 7-11, 2010.
80.
Shakuntala Kondraganti, Paul J. Boor, M. Firoze Khan, Rolf Konig, Kaphalia BS, G.A.S. Ansari
Decreased Phagocytosis of Trichloroethene Exposed HepG2 cells by RAW cells. 49th Annual
meeting of Society of Toxicology, Salt Lake City, Utah, March 7-11, 2010.
81.
Fernando H, Kaphalia BS, Ansari GAS. Progression of ethanol-Induced fatty liver with time in
alcoholic liver disease. 49th Annual meeting of Society of Toxicology, Salt Lake City, Utah, March 711, 2010.
82.
Varma TK, Kondraganti S, Kaphalia BS, Ansari GAS. Differentially Expressed MicroRNAs as
Biomarkers of Alcoholic liver Disease. 2010 ISBRA World Congress, Paris. September 13– 16,
2010.
83.
Fernando H, Kondraganti S, Bhopale KK, Kaphalia BS, Ansari GAS. Progression of EthanolInduced Fatty Liver with time in alcoholic liver disease. 2010 ISBRA World Congress, Paris.
September 13–16, 2010.
Kaphalia, B.S.
Page 23
84.
Booth DM, Huang W, Tepikin AV, Kaphalia BS, Sutton R, Criddle, DN. Role of non-oxidative
ethanol metabolism in pancreatic acinar mitochondrial dysfunction and cell death.” 41st Annual
Meeting, American Pancreatic Association, Chicago, IL, November 3-6, 2010. Pancreas 39,
Number 8, November 2010.
85.
Hassler S, Ma H, Kaphalia BS, Khan M, Nauduri D, Hulsebosch C. Oxidative stress in acute
spinal cord injury: Measures of lipid peroxidative and protein oxidation products. National
Neurotrauma Symposium, Las Vegas, June 14-17, 2010.
86.
Fernando H, Bhopale KK, Ansari GAS, Kaphalia BS. Lipidomic changes in the livers of hepatic
alcohol dehydrogenase-deficient deer mice after subchronic exposure to ethanol. 50th Annual
Meeting of Society of Toxicology, Washington D.C., March 6-10, 2011.
87.
Kondraganti S, Varma TK, Kaphalia BS, Ansari GAS. Differential expression of microRNA’s in
alcoholic and non-alcoholic fatty liver disease models. Research Society on Alcoholism’s Annual
Meeting, Atlanta, June 25-29, 2011.
88.
Bhopale KK, Fernando H, Kondraganti S, Ansari GAS, Kaphalia BS. Comparative studies on
ethanol induced early hepatic steatosis in different strains of rat. Research Society on Alcoholism’s
Annual Meeting, Atlanta, June 25-29, 2011.
89.
Fernando H, Soman KV, Kaphalia BS, Wiktorowicz JE, Ansari GAS. Liver proteomics in
progressive alcoholic steatosis. Research Society on Alcoholism’s Annual Meeting, Atlanta, June
25-29, 2011.
90.
Kondraganti S, Bhopale, KK, Ansari GAS, Kaphalia BS. Endoplasmic reticulum stress response in
ethanol-induced fatty liver in deer mouse model after subchronic and chronic ethanol
exposure. Research Society on Alcoholism’s Annual Meeting, Atlanta, June 25-29, 2011.
91.
Kondraganti S, Bhopale KK, Fernando H, Kaphalia BS, Ansari GAS. Differential expression of
genes and transcription factors related alcoholic hepatic steatosis in three strains of rat. Research
Society on Alcoholism’s Annual Meeting, San Francisco, CA, June 23-27, 2012.
92.
Wan J, Kondraganti S, Bhopale KK, Ansari GAS, Kaphalia BS. Dissecting endoplasmic stress
response in alcoholic pancreatitis. Research Society on Alcoholism’s Annual Meeting, San
Francisco, CA, June 23-27, 2012.
93.
Varma TK, Kondraganti S, Kaphalia BS, Ansari G.A.S. Differentially Expressed MicroRNAs as
Biomarkers of Alcoholic liver Disease. ISBRA Annual Meeting, Tokyo, Japan, Sept. 8-12, 2012.
94.
Ansari N, Zhang M, Wang CZ, Papaconstantinou J, Vasiliou V, Kaphalia BS. Chronic consumption
of alcohol causes corneal Injury in hepatic alcohol dehydrogenase-deficient deer mice: Role of
aldehyde dehydrogenases. ARVO, Annual Meeting, Washington, DC, May 5-9, 2013.
95.
Kaphalia L, Kaphalia BS, Calhoun WJ. Endoplasmic reticulum stress and unfolded protein
response in the lungs of deer mice after chronic exposure to ethanol. Am. Thoracic Society Annual
Meeting, Philadelphia, PA. May 17-23, 2013.
96.
Kaphalia BS. Metabolic basis and mechanism(s) of alcoholic pancreatitis; what we have learned
so far. Alcoholic Liver and Pancreatic Diseases Symposium. 8th International Symposium on ALPD
and Cirrhosis (ISALPD/C), sponsored by NIAAA, NIH, USA and ILBS, New Delhi, India, November
16-17, 2013.
Kaphalia, B.S.
Page 24
97.
Fernando H, Kakumanu R, Bhopale KK, Warnakulasuriya S, Kaphalia BS, Ansari GAS. Petrogenic
polycyclic aromatic hydrocarbons (PAHs) analysis of marine species after the Deep Water Horizon
Oil Spill. Gulf of Mexico Oil Spill & Ecosystem Science Conference, Mobile, AL on January 27-29,
2014.
98.
Fernando H, Bhopale KK, Ansari GAS, Kaphalia BS. Lipidomic Changes in the Pancreas and
Plasma of Hepatic Alcohol Dehydrogenase-Deficient Deer Mice after Long-Term Ethanol Feeding.
53rd Annual Meeting of the Society of Toxicology, Phoenix, AZ. March 23-27, 2014.
99.
Kaphalia L, Kaphalia BS, Kalita M, Calhoun WJ. Effects of Acute Ethanol Exposure on Cytokine
Production by Primary Airway Smooth Muscle Cells. Am. Thoracic Society Annual Meeting, San
Diego, CA. May 16-21, 2014.
100. Kaphalia L, Douglas HC, Jamaluddin M, Kaphalia BS, Calhoun WJ. Acute Ethanol Treatment
Inhibits Cytokine-induced Nuclear Factor-Kb (NF-kb) Activation in Airway Epithelial Cells. Am.
Thoracic Society Annual Meeting, San Diego, CA. May 16-21, 2014.
101. Bhopale KK, Soman KV, Wiktorowicz JE, Ansari GAS, Kaphalia BS. Analysis of pancreatic and
plasma proteins differentially altered in deer mice after chronic ethanol feeding. 37th Annual RSA
Scientific Meeting and 17th Congress of ISBRA, Bellevue, Washington. June 21-25, 2014.
102. Fernando H, Ju, H, Kakumanu R, Kaphalia BS, Ansari GAS. Distribution of petrogenic polycyclic
aromatic hydrocarbons (PAHs) in shrimps after the deep water horizon oil spill. Gulf of Mexico Oil
Spill & Ecosystem Science Conference, Houston TX, 2014.
103.
Kaphalia L; Kakumanu R; Kaphalia BS; Calhoun WJ. Effects of Acute Exposure of Ethanol and its
Metabolites on Primary Airway Smooth Muscle Cells. Am. Thoracic Society, Annual Meeting,
Denver, Colorado, May 15-20, 2015.
104.
Kaphalia L; Kakumanu R; Kaphalia BS; Calhoun WJ. Impaired alveolar macrophages functions
and increased fatty acid ethyl ester formation in freshly isolated human macrophage after acute
ethanol exposure. Thoracic Society, Annual Meeting, Denver, Colorado, May 15-20, 2015.
REVISED: January 2015