AP Environmental Science – Unit 7 Test Study Guide Test date: February 11, 2014 Chapter 14– Environmental Health and Toxicology Page # Terms Concepts 370-371 Bisphenol-A 371-378 environmental health physical hazard chemical hazard biological hazard cultural hazard infectious disease noninfectious (nontransmissible) disease radon lead poisoning asbestos polybrominated diphenyl ethers (PBDEs) SARS H1N1 (swine flu) West Nile virus malaria cholera HIV/AIDS toxicology toxicity toxicant environmental toxicology toxin Silent Spring carcinogen mutagen teratogen thalidomide neurotoxin Minimata Bay allergen endocrine disruptor hormone mimic hormone blocker phthalates pesticide drift polychlorinated biphenyls (PCBs) global distillation persistent bioaccumulation biomagnification DDT (diphenyl-trichloroethane) wildlife toxicology case history epidemiological study dose-response analysis dose response dose-response curve Understand the adverse health effects associated with bisphenol-A Differentiate between biological, chemical, physical, and cultural hazards. Understand hazards from radon, asbestos, lead poisoning, and various infectious diseases. Compare and contrast the impact of infectious vs. noninfectious diseases on society. Describe the ways in which society can prevent and combat disease. Explain the role of toxicologists. 378-386 386-392 Understand the importance of Rachel Carson’s Silent Spring for exposing the effects of synthetic toxicants in humans and their environment. Compare the different types of toxicants and their effects on the body; give examples. Explain the concept of pesticide drift. Describe global distillation (how polar ecosystems tend to concentrate toxins.) Figure 14.15 Explain what is meant by a chemical’s persistence. Understand bioaccumulation and biomagnification. Figure 14.16 Explain the role of wildlife toxicology. Describe the process of epidemiology. Be able to interpret a dose-response curve. Understand the toxicity information conveyed by an LD-50 or an ED-50. Explain what is meant by a threshold dose of a chemical. Explain why dose-response curves for organisms affected by 392-397 LD-50 ED-50 threshold acute exposure chronic exposure synergistic effects risk risk assessment comparative risk analysis risk management innocent-until-proven guilty approach precautionary principle Federal Insecticide, Rodenticide, and Fungicide Act of 1947 Toxic Substances Control Act of 1976 Food, Drug, and Cosmetic Act of 1938 FDA (Food and Drug Administration) CDC (Centers for Disease Control and Prevention) EPA (Environmental Protection Agency) Stockholm Convention on POPs endocrine disruptors often do not display the classic pattern. Differentiate between acute and chronic effects of toxicants. Define synergistic effects; Explain why these pose a particular difficulty for toxicologists. Explain the role of risk assessment, risk analysis, and risk management. Understand the role of government agencies and legislation in identifying toxicants and regulating their use and distribution. Differentiate between the innocent-until-proven-guilty approach and the precautionary principle. The test will involve 20 multiple choice questions and one free-response question.