UC IRVINE INSTITUTIONAL ANIMAL CARE AND USE COMMITTEE
APPENDIX F
MULTIPLE MAJOR SURVIVAL SURGERY
Complete this appendix if more than one major survival surgical procedure will be performed on any
single animal. A major surgical procedure is defined as one that penetrates or exposes a body cavity
or produces substantial impairment of physical or physiologic function.
Lead Researcher Name: Type here
Please provide the following information:
1. List all survival surgical procedures that may be performed on a single animal:
Type here
2. Clearly define the overall timeline of the procedures (i.e., how much time elapses between the
survival surgeries). Identify the experimental endpoint (i.e., when animals are euthanized):
Type here
3. Describe how animals will be monitored for healing between survival surgical procedures.
Indicate whether the timeline will be adjusted to accommodate variations in healing, etc.:
Type here
4. Describe your surgical and post-surgical record-keeping procedures. Attach a sample copy of
your record-keeping log:
Type here
5. Provide a scientific justification for performing more than one survival surgery on a single animal.
NOTE: Cost savings is not an acceptable justification for multiple survival surgery:
Type here
Appendix F
1