A&P- BIO 1110 Biochemistry Notes Composition of Matter The “stuff” of the universe Anything that has mass and takes up space Made of _________________: o What 4 elements make up 96% of the human body? What are atoms? o Every element’s atoms differ from all other elements. o Differences in atoms give each element different _______________ and ____________________ properties. Label the parts of the atom below and include charges: In an uncharged atom, the number of __________________ and __________________ are ___________________. Molecules versus Compounds: o Molecule o The atoms can be the same (H2) or different (H2O). Compound- A&P- BIO 1110 Biochemistry Notes All compounds are made of ___________________, but not all __________________ are ________________________. Chemical Bonding: o Electron shells, or energy levels, surround the nucleus of an atom. o Bonds are formed using the electrons______________ in the outermost energy level. o Each energy level can hold a specific number of electrons. o _____________________- Outermost energy level o Octet Rule: Except for the first shell which is full with ____ electrons, atoms interact in a manner to have _____ electrons in their valence shell. Types of Bonds: o Ionso ________________ bonds form between atoms by the transfer of one or more electrons. o _______________________ are formed by the sharing of two or more electrons. o Electron sharing produces molecules. A&P- BIO 1110 Biochemistry Notes Hydrogen Bonds: o More like attractions than bonds o Formed when a hydrogen atom (which is already covalently bonded to an atom) is attracted to another atom o Causes surface tension in water Organic Chemistry Molecules containing ______________________ Exception- _____________________________- because they are smaller, less complex molecules Carbon is special because it is ________________________- never loses nor gains electrons but always shares electrons Building blocks of cells What are the organic molecules? Carbohydrates: o Contain carbon, hydrogen, and oxygen in a ______________ ratio. o Monosaccharides: o Disaccharides: o Polysaccharides: A&P- BIO 1110 Biochemistry Notes o Carbohydrate Function: Lipids: o Also contain C, H, and O but contains less O than carbs o Lipid Function: Proteins: o Large molecules composed of combinations of 20 different amino acids. o Protein Function: o Structural Levels of Proteins: Primary – Secondary – Tertiary – Quaternary – A&P- BIO 1110 Biochemistry Notes o Enzymes: Proteins that act as biological catalysts (___________________) by lowering the energy needed for a chemical reaction (________________________) Usually end in ___________ Act on a substance called a _______________________ Mechanism of enzyme action: Substrate binds to the enzyme at its ______________. The enzyme and substrate fit together like a lock and key. The enzyme-substrate complex undergoes internal rearrangements that form the ________________. The enzyme releases the product(s). Enzyme is _________________ so it can act over and over again. A&P- BIO 1110 Biochemistry Notes ENZYME MECHANISM Nucleic Acids: o Composed of _____________________________________________________________ o Examples: o DNA: Genetic code: Tells the cells what _________________ to make and when to make them. Found inside the _______________. o RNA: Complementary copy of the ________ code. Made in the nucleus and exits to the cytoplasm. Used as instructions for building ____________. o What is transcription? o What is translation?