Video fact sources
In the U.S., nearly one million new cases of
sepsis occur each year, increasing by nine
percent every year.
http://medicalcenter.osu.edu/pdfs/about_osumc/sepsis.pdf. The
Ohio State University Medical Center, 2011
Sepsis is involved in nearly one in five deaths in
US hospitals.
http://www.sepsisalliance.org/downloads/2012_media_kit_fact_
sheet_sepsis.pdf. Sepsis Alliance
Sepsis has been named as the most expensive
in-patient cost in American hospitals in 2011 at
over $20 billion each year.
http://www.hcup-us.ahrq.gov/reports/statbriefs/sb160.jsp.
Agency for Healthcare Research and Quality, Healthcare Cost
and Utilization Project, Statistical Brief #160, 2013
Forty percent of patients diagnosed with severe
sepsis do not survive. Until a cure for sepsis is
found, early detection is the surest hope for
survival.
http://www.sepsisalliance.org/faq/. Sepsis Alliance
Research has shown that early recognition and
treatment of severe sepsis reduces morbidity
and mortality and will save lives. Dr. Larson
(Definitions #4)
http://www.sepsisalliance.org/downloads/Sepsis_Clinical_Fact_
Sheet.pdf. The Ohio State University Medical Center, 2011
Sepsis killed 258,000 people in the United
States in 2009 – one person every 2 minutes.
http://www.sepsisalliance.org/downloads/2012_media_kit_fact_
sheet_sepsis.pdf. Sepsis Alliance, 2012
Sepsis remains a salient problem in critical care
and emergency medicine, accounting for more
than 500,000 ED visits per year.
Wang HE, Shapiro NI, Angus DC, Yealy DM, “National
estimates of severe sepsis in United States emergency
departments.” Critical Care Medicine 2007;35(8):1928-36.
Seniors (65+) are 11 times more likely to be
hospitalized with sepsis and are significantly
more likely to die from sepsis.
http://www.sepsisalliance.org/downloads/2012_media_kit_fact_
sheet_sepsis.pdf. Sepsis Alliance, 2012
The mortality rate of sepsis is 0-60% per year.
Melamed A, Sorvillo FJ,” The burden of sepsis-associated
mortality in the United States from 1999-2005: an analysis of
multiple cause-of-death data.” Critical Care. 2009;13:R28.
Jacobi J., “Pathophysiology of sepsis.” American Journal of
Health-System Pharmacy. 2002;59 (suppl 1):S3-8.
1 — Seeing Sepsis | Video fact sources
More than 42,000 children develop severe
sepsis each year. Approximately 4,400 of these
children die, more than the number children who
die from pediatric cancers.
http://www.sepsisalliance.org/downloads/2012_media_kit_fact_
sheet_sepsis.pdf. Sepsis Alliance, 2012
Mortality from sepsis rises to 75% to 80% when
four or more organs fail.
http://www.sepsisalliance.org/downloads/2012_media_kit_fact_
sheet_sepsis.pdf. Sepsis Alliance, 2012
Sepsis is common and often deadly. It remains
the primary cause of death from infection,
despite advances in modern medicine like
vaccines, antibiotics, and intensive care.
http://www.world-sepsisday.org/?MET=SHOWCONTAINER&vCONTAINERID=11.
World Sepsis Day, 2014
Every year, severe sepsis strikes about 750,000
Americans. It’s been estimated that between
28 and 50 percent of these people die —far
more than the number of U.S. deaths from
prostate cancer, breast cancer and AIDS
combined.
Angus DC, Linde-Zwirble WT, Lidicker J, Clermont G, Carcillo J,
Pinsky MR, “Epidemiology of severe sepsis in the United States:
analysis of incidence, outcome and associated costs of care.”
Critical Care Medicine. 2001 Jul;29(7):1303-10
“Every hour a patient in septic shock doesn't
receive antibiotics, the risk of death increases
7.6%”
Kumar, A., Haery, C., Paladugu, B., Kumar, A., Symeoneides,
S., Taiberg, L., & Parrillo, J. E. (2006), “The duration of
hypotension before the initiation of antibiotic treatment is a
critical determinant of survival in a murine model of Escherichia
coli septic shock: association with serum lactate and
inflammatory cytokine levels.” Journal of Infectious Diseases.
193(2), 251-258.
2 — Seeing Sepsis | Video fact sources
Wood KA, Angus DC, “Pharmacoeconomic implications of new
therapies in sepsis.” PharmacoEconomics. 2004;22(14):895906