National Institute of Malaria Research (Indian Council of Medical Research) SECTOR-8, DWARKA, NEW DELHI-110077 Tender Document CATEGORY: A Last Date of Submission : 23.1.2012 Contents : 1. Tender Notice 2. Instruction to Bidders 3. General Terms & Conditions 4. Terms & Conditions for Indigenous Offers 5. Terms & Conditions for imported Offers 6. Format of Technical Compliance of specifications-Annexure ‘A’ 7. Deviation statement form-Annexure ‘B’ 8. Part of Price Bid- Annexure ‘C’ 9. After Sales Service Support Details-Annexure ‘D’ 10. List of Users-Annexure ‘E’ 11. Warranty Certificate-Annexure ‘F’ 12. Earnest Money Deposit form-Annexure ‘G’ 13. Check List-Annexure ‘H’ 14.Guidelines for furnishing breakup 15. Additional Information 16.Specification and allied Technical Details-Annexure-I Cost: RS.500.00 National Institute of Malaria Research Indian Council of Medical Research SECTOR-8, DWARKA, NEW DELHI-110077 TENDER NOTICE The Director, National Institute of Malaria Research (NIMR), Delhi invites Sealed Tenders in DOUBLE BID FORMAT from Principals/ Manufacturers, through their subsidiaries/affiliates or their accredited/authorized sole selling agents in India. The bids should in the form of (1) TECHNICAL BID providing detailed specifications, operating conditions offered and installation requirements together with manufacturer’s original brochure supporting the specifications and Earnest Money Deposits in sealed cover and (2) PRICE BID for supply, training, installation, additional warranty/AMC and commissioning of the following items: CATEGORY- A: Laboratory Apparatus & Equipment: Autoclave,BOD Incubator, Pipetting robot, Centrifuge(Table Top), Centrifuge, Centrifuge Refrigerated, Circulating Water Bath,Photoperiod simulator,Data Logger System,Data Logger Module,Deep Freezer -20°C,Electronic Balance, Electrophoresis apparatus with power supply, Electrophoresis power pack, ELISA Reader with washer, Florescent Microscope, Fogging Machine (A= Thermal Fogger B= Cold Fogger),Flow Cytometer,Gel Documentation System, Gel Rocker, Hot Air Oven, Incubator, Laminar Flow,Liquid Nitrogen Container (Big & Small),Microscope (Compund,Stereo), Microscope Inverted with bright field,phase contrast & DIC System,Micropipetts, Multichannel Pipetts, Magnetic Stirrer, Microcentrifuge,Multiplex Protein Bead based Array System, Nano drop spectrophotometer,Digital pH Meter,PCR(Gradient ), Thermal Cycler, Pharmaceutical Refrigerator, Sonicator(for large& Small volume),Tissue Dissociator, UV Spectrophotometer, UV Spectrophotometer with PC & Printer,Vortex, Vertical Autoclave(Heavy Duty), Vacuum Pump,Shaker water bath,2-D Gel Electrophoresis System, Vertical Electrophoresis with electroblotting & power pack,Membrane Feeding Apparatus, Bottle top Dispenser(1-100ml), Nitrogen Gas Cylinder,Shaker,Auto Nanolitre Injector,Microwave,Battery operated Incubator,Stratacoolers. CATEGORY- B: Audio Visual Equipments: Video Conferencing System, Interactive Display System,55” Full HD 3D HD TV CATEGORY- C: Computers/Peripherals: Computer Server, Desktop Computer, iPad-2,Laptop Computer, Mac Book Pro, ColorPrinter, Thermal Printer, Multipurpose Printer, Laserjet Printer, GIS Software (Arch View & Arch Info), Bandwith Management Software. CATEGORY- D: Electrical Installations & Equipment: Air Curtain,Water Cooler, Water Purifier The tender documents can be obtained (in person) by depositing a non-refundable amount of Rs. 500.00 (rupees five hundred only) for each category of tender separately in the shape of a Banker’s Cheque/Demand Draft, drawn in favour of “Director, National Institute of Malaria Research”, payable at Delhi from the office of NIMR at Sector-8,Dwarka, New Delhi (Room No.405 Ground Floor). Outstation vendors can download the tender form from NIMR website (www.mrcindia.org) and submit the same along with the document fee of Rs.500.00 in the shape of Demand Draft in favor of “Director, National Institute of Malaria Research” payable at Delhi. Tender application forms are not transferable. The detailed specifications/terms and conditions of all the items listed above can be downloaded from NIMR web site at http://www.mrcindia.org. IMPORTANT POINTS TO BE NOTED Opening and closing dates and time of issue of tender documents Last date and time of submission of tender Address for issue and submission of tender documents Non-refundable fee for tender document for each Category of tender(i.e. A,B,C,D) Tender documents are also available at website Earnest Money Deposit (EMD) (Interestfree, refundable) (to be sent with the Technical Bid) Date of Opening: 30th December,2011 10 AM Date of Closing: 13th January 2012, 5 PM 23rd January 2012, upto 5 PM Director National Institute of Malaria Research Sector-8, Dwarka, New Delhi-110077 (Ph: 011-25307405, 25307407) Rs. 500.00 by Demand Draft/Banker Cheque in the name of Director NIMR, payable at Delhi If required by post, postal charge of Rs. 50.00 has to be added. www.mrcindia.org, The document can also be provided in CD on request. 3% of the total cost of equipment (for each equipment separately) by Demand Draft/ Banker cheque in the name of Director NIMR, payable at Delhi ( along with Technical Bid in a separate envelope) NOTE:The specified tender fee should accompany each category of tender document. Director NIMR,Delhi Eligibility Criteria 1. Principals/Original Equipment Manufacturer’s with Sales and service support facilities in India through their branch office / Indian Agent 2. Indian agent with proven sales (at least three years) and service support in India representing foreign principals / Original Equipment manufacturers Firms/ companies with either of the above eligibility criteria are eligible to quote for the equipments with ISO as well as CE Certification. The Indian agency / dealership certificate with details of sales and service support should be enclosed with the technical bid. Instructions to Bidders 1. Tender should be submitted in two parts viz. Part I – Technical Bid (without Prices) and Part II - Price Bid. 2.(a) Formats for Bids: The tenderers are requested to give detailed Quotation in the formats mentioned in the Tender Document. The Tenderer should furnish a Technical Compliance Statement for each parameter and every model in the format ‘Annexure A’ and enclose in the Technical Bid exactly in the order as mentioned in the tender document. If any Tender terms and conditions are deviated by the tenderer, the Deviation statement ‘Annexure B’ should be enclosed in the Technical Bid. If there are no Deviations then the Tenderer should record ‘No Deviations’ in the Deviation Statement and enclose in the Technical Bid. The Price Bid for each and every model should be in the format enclosed as ‘Annexure C’. The After Sales support details must be in the format ‘Annexure D’ and enclosed in the Technical Bid. The list of users / firms who purchased similar equipment (especially other ICMR, CSIR labs, IITs, IISc etc.) must be in the format ‘Annexure E’ and enclosed in the Technical Bid with Prices blacked out and with Prices in the Price Bid. The warranty certificate to be given by the Manufacturer / vendor should be as per ‘Annexure F and enclosed in the Technical Bid’. If the Tenderer is furnishing EMD by Bank guarantee then the format given in Annexure G is to be used. The Tenderer should fill up the check list Annexure H’ and enclose with the Technical Bid. 2(b) Each tender should be submitted separately for each category of tender with forwarding letter in a separate envelope. However, if anybody is quoting many items, they should submit only one soft copy. All quotations can be mailed in a same envelope. 3. Tender Document Fee:- Tender Document Fee is payable by companies who have downloaded the tender documents from the website http://www.mrcindia.org . They should submit the tender along with a bank draft of Rs. 500/- (non-refundable) payable to Director, NIMR at Delhi for each category of tender separately which should enclosed with the Technical Bid. 4. Earnest Money Deposit:- The Technical Bid (Part-1) should be accompanied by Earnest Money Deposit as indicated in our detailed technical specifications in the form of Demand Draft/Bank Guarantee (Format enclosed Annexure G) from any Nationalised Indian Bank drawn in favour of Director, National Institute of Malaria Research, Delhi. Tenders not accompanied with EMD in the Technical bid will be summarily rejected. The EMD will carry no interest. EMD received after due date shall not be accepted under any circumstances. EMD will be refunded in due course to the unsuccessful tenderers. The EMD is liable to be forfeited, if the Tenderer withdraws or amends, impairing or derogates from the tender in any respect. 5. Exemption from payment of EMD:- Firms registered with DGS&D and NSIC who are exempted from payment of EMD are allowed exemption from payment of EMD if the product being quoted is actually manufactured by them and the product is registered with these agencies. Firms registered with these agencies selling products of other companies and not manufacturing the products being quoted by them are not allowed exemption from payment of EMD. To avail EMD exemption, the firms should submit a legible photocopy of valid Registration Certificate of the products manufactured and registered with DGS&D and NSIC in a separate envelope along with the technical bid. 6 Bid Submission:- Completed tenders signed by the Tenderer on each page at the bottom, super scribing the Enquiry Number and closing date should be sent to The Director, National Institute of Malaria Research ( ICMR) Sector-8, Dwarka, New Delhi-110077 7.Each quotation sent by post/courier is to be enclosed in Double Cover. The inner cover should be SEALED WITH WAX AND SUPERSCRIBED as “Quotation for “…………” Tender Enquiry No. ………………….. Dated ……… Date of Opening ……………”. The Separate covers containing the Technical Bid and Price Bid should be clearly Super scribed as “Technical Bid” and “Price Bid” respectively. The outer cover should bear only the Address of the office without any indication that there is a quotation within. Quotations delivered personally should be put in the Tender Box kept at NIMR office at Sector-8, Dwarka, New Delhi. The tenderers themselves should ensure that their tenders with all requirements reach this office within the stipulated date and time. No latetenders or delayed-tenders will be accepted. NIMR will not be responsible for non-receipt / postal delays. 8. Bid Submission last date and time: - The last date and time for submission of both technical and Price bids is 16-1-2012 (5.00 P.M. Indian Standard Time). 9. Technical Bid Opening Date and Time: - The technical bid of the vendors whose tenders have been received at NIMR before the closing date and time will be opened on 24.1.2012 (11.00 a.m. Indian Standard Time). 10. Price Bid Opening: - Only those bids, which meet the technical `specifications, will be considered for opening of Price Bid. The names of successful vendors who meet the technical specifications will be displayed in the Institute website /(http://www.mrcindia.org ) and in the notice board at NIMR, Delhi. Price Bid Opening Date and Time: - The price bid of the vendors whose tenders have been received at NIMR before the closing date and time will be opened on 10.2.2012 (11.00 a.m. Indian Standard Time). Price Reasonability Certificate: Please quote best minimum prices. A certificate regarding the quoted rates must be given by the bidders to this effect that they have neither quoted nor sold/ supplied the same item to any other customer on lesser rates than those offered to NIMR. 11. Language of Bid: - The bid prepared by the bidder, the technical brochures and all correspondence relating to the bid shall be written in English language only. 12. Validity of Bid: - Bids shall remain valid for 90 days after the date of opening at NIMR. A bid valid for a shorter period may be rejected as non responsive by NIMR. In exceptional circumstances NIMR may solicit the vendor’s consent to an extension of the period of validity. The EMD provided should also be suitably extended. The vendor accepting the request for extension will not be permitted to modify the bid. 13. INTERIM CORRESPONDENCE WILL NOT BE ENTERTAINED . 14. Tender Documents are not transferable under any circumstances. 15. The bid should be complete in all respects otherwise liable to be rejected. Tender should be duly signed. Incomplete and unsigned bids will not be considered. 16. Quotations must be clearly written or typed without any overwriting. The person signing the bid must attest all corrections / over writing. 17. All rates / prices in Price bid should be given in figures and in words. If there is any discrepancy between the Prices given in figures and words the higher of the two shall be taken for our comparison. 18. Installation of Equipments: Equipments will be installed in NIMR Delhi and also in any of the Field Units located at Hardwar, Raipur, Ranchi, Guwahati(Assam), Goa, Jabalpur, Nadiad, Bangalore, Chennai, Rourkela without any additional cost. 19. Director NIMR reserves the right to defer the above dates or cancel the Tender in part or whole without assigning any reason whatsoever. GENERAL TERMS AND CONDITIONS 1. Printed terms and conditions of the firms sent along with offer, if any shall not be binding on us, if they are in full or in part are not consistent with the terms and conditions specified in this Tender. 2. Supply means Supply, installation, and commissioning and satisfactory demonstration of the whole system as per the specification ordered for. 3. Delivery:- Generally the delivery of the goods should be made within 8 weeks from the date of placement of purchase order. The delivery time for the equipment quoted by you should be clearly mentioned. 4. (1) Liability for Late Delivery and Non Delivery:- If the Vendor fails to deliver the Goods within the time as per purchase order, a sum equivalent to 1 (one) percent of the Order Value for each week of delay or part thereof until actual delivery, will be deducted from the Contract Value, as liquidated damages, subject to maximum deduction of 5 percent of the Order Value. (2) For delay in installation beyond stipulated period indicated in the supply order will attract penalty @ 1% per week with a maximum of 5 %( beyond mutually agreed Installation & Commissioning schedule). In case the supplier/agent defaults in the supply of goods as per the order placed by, National Institute of Malaria Research ( ICMR)Sector-8, Dwarka, New Delhi110077 (INDIA) fails to deliver the goods within the stipulated time as indicated in the supply orders or even within the extended delivery date, the supply order lying with the supplier/agent should stand automatically cancelled and NIMR shall be at liberty to get the goods supplied from other available sources at the risk and cost of the defaulting supplier/agent. The additional expenditure so incurred for getting the goods shall be borne by the defaulting supplier/agent in addition to forfeiture of Earnest Money Deposit and if he fails to compensate the entire loss and if the Earnest Money Deposit are not sufficient, action will be taken to realise the loss. 5. Inspection: - NIMR may decide to inspect the goods in the following modes. 1. Pre shipment inspection may be done by the Personnel of NIMR 2. Pre shipment inspection may be done by any reputed Inspection agency. NIMR shall inspect and test and where necessary reject the goods after the goods arrival at NIMR in addition to Pre shipment inspection if any. The Pre shipment inspection shall in no way be limited or waived by reason of the goods having been inspected, tested and passed byNIMR or the inspection agency prior to shipment. 6. Packing:- The Supplier shall provide such packing of the Goods as is required to prevent their damage or deterioration during transit to their final destination as indicated in the Contract. The packing shall be sufficient to withstand, without limitation, rough handling during transit and exposure to extreme temperatures, salt and precipitation during transit and open storage. Packing case size and weights shall take into consideration, where appropriate, the remoteness of the Goods' final destination and the absence of heavy handling facilities at all points in transit. Suppliers will have to make good the shortages, if any, which are revealed after opening the packages. The stores which are spoiled / damaged during transit due to faulty packing will have to be replaced by the suppliers. 7. The Director, NIMR reserves the right to accept the delivery in part or in full. Damaged and unaccepted supply will be returned to the vendor at vendor’s risk and cost. 8. Force Majeure clause:- The vendor shall not be liable for forfeiture of its bid security, performance security, liquidated damages or termination for default, if and to the extent that, its delay in performance or other failure to perform its obligations under the contract is the result of an event of Force Majeure. Force Majeure means an event beyond the control of the supplier and not involving the vendor’s fault or negligence and not foreseeable. Such events may include, but are not limited to, acts of the vendor either in its sovereign or contractual capacity, wars or revolutions, fires, floods, epidemics, quarantine restrictions and freight embargoes. If a Force Majeure situation arises the Vendor shall forthwith notify NIMR in writing of such conditions and cause thereof. Unless otherwise directed by NIMR in writing, the vendor shall continue to perform its obligations under the contract as far as is reasonably practical, and shall seek all alternative means for performance not prevented by the Force Majeure event. 9. Dimensions and weight:- The dimensions of the equipment, the net weight and gross weight of the equipment should be clearly mentioned in the technical bid. 10. Applicable Law:- This tender documents and contract is subject to the Indian law and Indian Contracts Act as amended from time to time. 11. Jurisdiction:- All disputes are subject to the courts within DELHI., India jurisdiction only. 12. Full and complete set of documentation manuals, Operation manuals and service / Maintenance manuals to be provided in English. 13. Resolution of Disputes:- The NIMR and the Firm shall make every effort to resolve amicably by direct informal negotiation any disagreement or dispute arising between them under or in connection with the Purchase. If, after thirty days from the commencement of such informal negotiations. NIMR and the Firm have been unable to resolve amicably a Contract dispute, either party may require that the dispute be referred for resolution to the formal mechanisms as under. In the case of a dispute or difference arising between NIMR and the Firm relating to any matter arising out of or connected with the agreement, such dispute or difference shall be referred to the award of two Arbitrators, one Arbitrator to be nominated by NIMR and the other to be nominated by the Firm or in the case of the said Arbitrators not agreeing, then to the award of an Umpire to be appointed by the Arbitrators in writing before proceeding with the reference, and in case the Arbitrators cannot agree to the Umpire, he may be nominated by the Director General, Indian Council of Medical Research, New Delhi. The award of the Arbitrators, and in the event of their not agreeing, of the Umpire appointed shall be final and binding on the parties. The Indian Arbitration & Conciliation Act 1996, the rules there under and any statutory modification or re-enactments thereof, shall apply to the arbitration proceedings. The venue of arbitration shall be NIMR, Delhi . 14. Language of contract:- The contract / Purchase Order and all correspondence relating to the contract / Purchase order shall be written in English language only. 15. Notices and communications:- For all purposes of all notices, the following address shall be used by the Bidder / Vendor:The Director, National Institute of Malaria Research ( ICMR) SECTOR-8, DWARKA, NEW DELHI-110077. 16. Termination for default:- NIMR may, without prejudice to any other remedy for breach of contract, by written notice of default to the Vendor, terminate the contract in whole or in part: 1. If the vendor fails to delivery any or all the goods mentioned in the purchase order or within any extension thereof granted by NIMR 2. If the vendor fails to perform any other obligation under the order 1. If the vendor in the judgment of NIMR has engaged in corrupt of fraudulent practices in competing for or in executing the order. 2. If the vendor is declared insolvent / bankrupt in a court of law or such proceedings are contemplated by NIMR. 3. If the vendor goes into dissolution or liquidation or transfers substantial part of its business or assets. 17. Termination for Cause:- NIMR may at any time terminate the purchase order in whole or in part by giving written notice to the vendor, without compensation to the vendor: 18. Intellectual Property Rights:- The Vendor shall indemnify NIMR against all third party claims of infringement of Patent, Trademark, Copy Rights or Industrial Design rights arising from the use of the equipment / goods or any part thereof in India. 19. Training clause:- Specific mention should be made about the Training facility available in India or abroad. If extra, its cost should be mentioned. 20. Pre installation requirements:- The Technical Bid must contain details with specification of items required for REQUIREMENTS (AIR / WATER) ELECTRICAL installation (PRE-INSTALLATION POWER / TEMPERATURE & HUMIDITY CONTROL / FOUNDATION / SPACE and any other requirements to complete Installation at NIMR, Delhi. 21. Order acknowledgment:- Within 15 days from the date of Purchase order / Contract the Order / Contract should be acknowledged by the Vendor (Indian OEM / Foreign Principal) failing which it will be deemed that the vendor is not interested in the contract / purchase order and the bid security will be forfeited without any further recourse. 22. Performance Bank Guarantee:- The vendor should furnish a performance bank guarantee from a nationalized bank in India. The Bank guarantee should cover the (warranty period of three years) from the date of installation of the equipment. The value of the Bank guarantee is 10% of the LC value. This PBG must be submitted prior to opening of F.L.C. For Indigenous Equipment PBG will be 10% of the ordered value of the equipments which is to be submitted before delivery of equipments. 23. The system should be able to operate on 220/230V, 50 Hz single phase AC power supply. 24. Risk Purchase Clause:- If the Supplier fails to deliver the goods within the maximum delivery period specified in the Purchase Order, NIMR may procure, upon such terms and in such a manner as it deems appropriate, Goods or Services similar to those undelivered and the Supplier be liable to NIMR for any excess costs incurred for such similar Goods or Services. 25. Responsibility:- The responsibility lies with the successful Tenderer, if any damage or loss to the property of the Institute occurs while executing the order. 26. Warranty, Defects & Liability Period:- (Warranty) The rates should be valid up to 3 years Comprehensive warranty and 2 years Non-comprehensive services for equipment free of cost from the date of completion of satisfactory installation and demonstration as certified by NIMR. The supplier should rectify free of cost any defect that may develop in the system during the warranty period. The warranty period shall automatically stand extended by the time taken to rectify the defects. The Firm should give a warranty certificate as per the format attached in the Tender Document. The spare parts of the equipment shall be provided up to 10 years to maintain the equipment. 27. User List:- A signed list of similar equipment / stores supplied by the tenderer to the Other ICMR, CSIR labs, R & D Institutions like IITs, IISc, Railways, MES, State and Central Govt. Departments, Undertakings, large private concerns in the past three years, should be furnished, indicating capacity, model, type of equipment address of the parties to whom supplied, and order number and date (applicable to equipment, plant and machinery). 28. The acceptance of the quotation will rest with the Director NIMR who does not bind himself to accept the lowest quotation and reserves the right to himself to reject, or partially accept any or all the quotations received, without assigning any reason. The quotations are liable to be rejected, if any of the conditions are not complied with. TERMS & CONDITIONS FOR INDIGENOUS OFFERS 1. Prices:- Prices in the Price Bid should be quoted Either Ex-works or on Free Delivery at NIMR basis. If it is Ex-works then the packing and forwarding charges, Insurance (from ware house to warehouse with all risks covered on 110% of the value) charges, Freight charges by road (any reputed transporter) / Courier (any reputed courier) on door delivery basis must be clearly mentioned. Quotations without these details will be summarily rejected. 2. Excise duty:- This institute is exempted from payment of Excise duty as per st notification No. 10/97 – Central Excise, dated 1 March 1997. Hence excise duty exemption certificate will be forwarded along with the purchase order for excise free shipment. 3. Taxes:- In the case of indigenous item, the RATE OF SALES TAX / Value Added Tax should be clearly indicated wherever, chargeable. This office is eligible to issue concessional sales tax certificate 4. Packing and Forwarding:- The packing and forwarding charges should either be included in the Unit rate or quoted as a percentage of the PO or quoted as a lump sum amount. 5. Insurance:- If the contract requires the Vendor to insure the goods, the vendor unless otherwise agreed on the face hereof, insure the goods 1. For a value equal to one hundred and ten percent (110%) of the order value on warehouse to warehouse basis. 2. On the basis of All Risks (Institute Cargo clauses) or on equivalent terms 3. With underwriter (s) or insurance company(ies) of good repute 4. Any additional insurance coverage shall be arranged by vendor upon the special request and on the account of NIMR 5. Provide all assistance to NIMR in case of any claim is made on the insurance company on the basis of the policy 1. Excise duty Registration Number 2. Sales tax / Value Added Tax Registration Number 3. Service tax registration number 6. Freight:- If the consignment has to be dispatched by Road transport / courier then only reputed transporters / reputed courier are to be used by the vendor and consignment to be dispatched on Freight pre paid basis and door delivery basis. 7. Banker’s address:- Our banker is CANARA BANK,NEW DELHI. All cheques / demand drafts will be crossed account payee only. 8. Registration Numbers:- The following certificate copies should be attached with the technical bid 9. Service support:- The post installation warranty support is required to be provided by your Delhi / nearest place service centre. Hence mention the contact address, with contact person and telephone numbers. 10. Payment terms:- No advance payment shall be made. 100% Payment will be released within 30 days after successful installation of the equipment at NIMR and submission of 10% against a performance Bank Guarantee valid till the expiry of the comprehensive warranty period and additional three months thereafter. 11. Documents:- The following documents are required. The invoice will not be paid until supported by all the supporting vouchers. 1. Invoice in triplicate showing the Purchase order / contract number, goods description, quantity, unit price and total amount The invoice should be duly Pre receipted on a revenue stamp (revenue stamp mandatory vide Indian Stamp Act for amount exceeding Rs. 5000/-) 2. Acknowledgement of the receipt of goods from the consignee by the transporter / courier 3. Insurance certificate / Premium Paid Voucher / Policy if any 4. Manufacturer’s warranty certificate 5. Inspection certificate issued by the nominated inspection agency, if any (nominated as per contract) or the Vendor’s inspection / testing report 6. Packing list (two copies) identifying the contents of each package 7. Delivery challan / Delivery note in triplicate TERMS & CONDITIONS FOR IMPORTED OFFERS 1. Cost:- Ex-Works Price to be clearly indicated in the Price Bid. The Indian agents commission if any will be subtracted from the Ex-works Price in the Purchase Order . FOB Charges up to the nearest gateway International airport to be indicated in the Price bid. 2. Import License: - The ordered materials are being imported under Open General License. Hence, no license is required. 3. Export License:- If the ordered equipment are subject to Vendor procuring an export license from the designated government agency / Country from where the goods are shipped / sold , the vendor has to mention the name, address of the government agency / authority. The vendor must also mention the time period within which the license will be granted in normal course. 4. Customs duty: - This institute is exempted from payment of Customs duty as per notification No. 51/96 – Customs dated 23.7.1996. 5. INDIAN AGENT’S COMMISSION, if any: If you have any Agents in India, please show specifically whether the amount of commission payable to them is included in the Ex-works Price. Please note that under the Government of India regulations, Commission to Indian Agents is payable only in Indian Currency. The role played by the Indian Agents in rendering assistance to NIMR must also be specified and copy of authorization letter enclosed in technical bid. 6. COUNTRY OF ORIGIN: Please specify PLACE / Country of Origin and the Place / country from which goods will be finally shipped. These particulars are very important for establishment of L/C, arranging insurance etc. 7. Forwarding Agent:- NIMR has an existing contract with …Aakanksha Enterprises………………………………………..for providing the services of a Freight Forwarder. All FCA / FOB shipments will be consolidated by the agents of M/s……………………………………………………... 8. Clearing Agent:- NIMR has an existing contract for clearance of imported cargo with M/S …………………………….All the pre-shipment alerts and post shipment documents should also be forwarded to them. 9. Inspection:- The Indian agent / Indian branch Office will be intimated immediately after the receipt of the consignment at NIMR Stores. The consignment will be jointly inspected by the Stores personnel, Technical Personnel of NIMR and the representative of Indian agent within 24 hours after receipt. The consignment will be compared with the purchase order and packing list. Any excess supply, shortage, wrong supply and any damage will be noted immediately and intimated to the vendor. Damaged and unaccepted supply will be returned to you at your risk and cost. The vendor should ship the shortage and replace the damaged / wrong shipment at no cost to NIMR. 10. Installation and commissioning:- NIMR requires the assistance of the Indian agent / Indian branch Office during installation, commissioning of the Equipment. Training for the personnel at NIMR is also mandatory when specifically asked for in the contract. 11. Service: - The Indian agent / Indian branch office of the foreign principal should support the equipment fully during the warranty period. If NIMR requires AMC during the post warranty period the Indian agent / Indian branch office must fully offer full support. 12. Merger and Acquisition:- Any merger and acquisition of the Foreign principal by other companies / firms must be intimated to NIMR immediately. 13. Change of Indian Agent:- If there is any change of Indian agent during the warranty period / post warranty period the foreign principal must intimate NIMR immediately with the new company’s name and address. 14. Insurance:- If the contract requires the foreign principal to insure the goods, the vendor unless otherwise agreed on the face hereof, insure the goods 1. For a value equal to one hundred and ten percent (110%) of the FOB amount of the contract on warehouse to warehouse basis. 2. On the basis of All Risks (Institute Cargo clauses) or on equivalent terms 3. With underwriter (s) or insurance company(ies) of good repute 4. Any additional insurance coverage shall be arranged by vendor upon the special request and on the account of NIMR 5. Provide all assistance to NIMR in case of any claim is made on the insurance company on the basis of the policy 15. Import Payment:- Letter of Credit will be established for 100%. Payment will be released in two parts: 1. 80% after presentation of original documents after dispatch of the item ordered 2. 20% after satisfactory supply, installation and commissioning and demonstration of the item ordered and furnishing 10% performance Bank Guarantee on any Nationalized Bank in India by Foreign Principal / Indian Agent valid till the expiry of the comprehensive warranty period and additional three months thereafter. 3. If the Letter of Credit is required to be extended / reinstated for reasons not attributable to NIMR, the Bank Charges thereof shall be to the beneficiary’s account. 16. Documents: - The following documents are required by us at the time of negotiation of documents for Letter of Credit within 48 hours of shipment. 1. Commercial invoice – 4 copies (original) 2. Packing list – 2 copies 3. Country of Origin – 1 copy 4. Master Airway Bill – 2 copies 5. Warranty certificate – 2 copies Director, NIMR, Delhi. Annexure A FORMAT OF TECHNICAL COMPLIANCE OF SPECIFICATIONS Sl. No. Name of Specifications /Parts/ Accessories of Tender Enquiry 1 Specifications of Quote Model/Part/ Accessory Compliance Whether Yes or No Deviation, if any to be indicated in unambiguous terms (The Compliance/ Deviation Should be Supported by relevant Technical Literature) Technical justification for the Deviation, if any. If Specification is Superior/ inferior than asked for in the enquiry, it should be clearly brought out in the justification Specifications for Instrument Signature of Tenderer If the Tenderer offers more than one model, then the Technical Compliance Statement must be enclosed for each and every model separately. If the Tenderer fails to enclose the compliance Statement, his bid is likely to be rejected. Annexure B Deviation Statement Form The Following are the particulars of the deviations from the requirements of the Tender Document terms and conditions: SL. No. Clause in the terms and conditions Deviation Justification for the deviation Signature of Tenderer Annexure C (Part of price bid) Cost of The Equipment, parts and Accessories and Other Details Offered (Must be enclosed in the Price Bid only for every model quoted for) Sl. No. 1 Item (If the Tenderer offers more than one model, then this format should be furnished for each model separately) Specifications for Instrument Unit Amount Price (Currency) Annexure D After Sales Service Support Details Sl. No. Local Address, Telephone numbers, Fax numbers and email address of the agent who will provide after sales support Number of engineers / service personnel who are stationed at the local address Nature of training imparted to the service personnel especially at the principal’s company The list of consumables held at all times by the agent Important : When the tenderer Stations only skeleton staff at the local address and stations the key service providers at other locations, the address of the location etc. have to be clearly brought out. The lead-time required for attending such out station calls should also be clearly brought out. The Tenderer should clearly indicate in which cases it would be essential for the equipment to be sent to foreign principal for servicing or in which cases it will be essential for service personnel to come from foreign principal Annexure E List of Users for a period of 3years preceding this tender ( If possible similar equipment) Sl. No. Order for similar equipment placed by (full address of purchaser with contact person, telephone number) Purchase Order Number and Date Description, model and quantity ordered Price Charged Important: (Rates to be blacked out in the technical bid. The Price bid of Tenderer must contain the price Charged) Date of completion of delivery as per contract and Date of installation / commissioning as per contract Reasons if any, for delay in delivery, installation and commissioning Signature of Tenderer Annexure F WARRANTY CERTIFICATE We Warrant that everything to be supplied by us hereunder shall be brand new, free from all defects and faults in materials, workmanship and manufacture and shall be of the highest grade and quality and consistent with the established and generally accepted standards for material of the type ordered shall be in full conformity with the specification, drawing, or samples, and operate properly. We shall be fully responsible for its efficient operation. This Warranty shall survive inspection of any payment or and acceptance of the goods but shall expire after (expect in respect of complaints of which the contractor has been notified prior to such date) 36 months after their successful installation, commissioning and acceptance by NIMR, Delhi. The obligations under the Warranty expressed above shall include all costs relating to labor, spares, maintenance (preventive and unscheduled) and transport charges from site to the manufacturers work and back and free repair/adjustment or replacement at site or any parts of the equipment which under normal and proper use and maintenance proves defective in design, material or workmanship or fails to conform to the specifications previously given by the NIMR to the contractor. Signature of the Tenderer Annexure G BID SECURITY/EARNEST MONEY DEPOSIT FORM Whereas ...................……….......1 (hereinafter called “the Bidder”) has submitted its bid dated...................... (Date of submission of bid) for the supply of............................. (name and/or description of the goods) (Hereinafter called “the Bid”). KNOW ALL PEOPLE by these presents that WE ..................... (name of bank) of .................. (name of country), having our registered office at ...............……….(address of bank) (hereinafter called “the Bank”), are bound unto ............................. (name of Purchaser) (hereinafter called “the Purchaser”) in the sum of _______________________ for which payment well and truly to be made to the said Purchaser, the Bank binds itself, its successors, and assigns by these presents. Sealed with the Common Seal of the said Bank this ____ day of _________ 20 __________THE CONDITIONS of this obligation are: 1. If the Bidder withdraws its Bid during the period of bid validity specified by the Bidder on the Bid Form; or 2. If the Bidder, having been notified of the acceptance of its bid by the Purchaser during the period of bid validity: a) fails or refuses to execute the Contract Form if required; or (b) fails or refuses to furnish the performance security, in accordance with the Instruction to Bidders. We undertake to pay the Purchaser up to the above amount upon receipt of its first written demand, without the Purchaser having to substantiate its demand, provided that in its demand the Purchaser will note that the amount claimed by it is due to it, owing to the occurrence of one or both of the two conditions, specifying the occurred condition or conditions. This guarantee shall remain in force up to and including forty five (45) days after the period of the bid validity, and any demand in respect thereof should reach the Bank not later than the above date. ................................... (Signature of the Bank) ____________________________________________ 1 Name of Bidder Annexure H Check List to be furnished by the Tenderer 1. When Quotation is from Indian agent / Dealer – whether letter of Authorisation of Foreign principal is enclosed in the techno-commercial bid – Yes / No. 2. For Two Bid System – Whether Techno commercial and Price Bids are kept in separate envelopes duly indicating Techno – Commercial Bid and Price Bid respectively – Yes / No. 3. Whether Tender Number, due date and opening date have been written in all the envelopes – Yes / No. 4. In Case of Tenderers who downloaded the documents from the website – Whether the tender document fee (Demand draft in favour of Director, National Institute of Malaria Research, Delhi-54) is enclosed along with Techno commercial bid – Yes / No. 5. EMD – Whether the required EMD is Enclosed along with the Techno commercial bid – Yes / No. 6. In case the firm is exempted from payment of EMD (Like SSIs registered with NSIC, firms registered under DGS & D) – Whether Valid Permanent Enlistment Certificate of NSIC / Valid DGS & D Rate Contract copy is enclosed in the Techno Commercial Bid – Yes / No. 7. If You are an Indian Agent / Dealer / Distributor for a foreign principal have you enclosed the Letter of Authorisation / Agency certificate in the Techno Commercial Bid – Yes / No. 8. Whether Technical compliance Statement in the format given in Annexure A is enclosed in the Techno Commercial Bid– Yes / No. 9. Whether the Deviation Statement in the format given in Annexure B is enclosed in the Techno Commercial Bid – Yes / No. 10. Whether Details of After sales support is given as per format in Annexure D and is enclosed in the Techno Commercial Bid– Yes / No. 11. Whether the List of Users is given as per Annexure E and is enclosed in the Techno Commercial Bid– Yes / No. 12. Whether the warranty certificate is enclosed as per Annexure F and is enclosed in the Techno Commercial Bid – Yes / No. 13. Whether the Pre-installation requirements is given in the Techno Commercial bid – Yes / No. 14. Whether the Price bid is as per the format given in Annexure C – Yes / No. 15. Whether the Price Bid has been signed in every page – Yes / No. Signature of Tenderer General Guidelines for furnishing breakup Total Cost of the Basic Equipment / System (In case of Imports without incidence of Customs Duty.) Ex Works Prices Cost of Handling, inland Transportation, insurance charges etc. / FOB Charges ( Nearest International Airport ) Estimated Cost of Air / Ocean Freight, insurance, transportation etc. upto New Delhi airport / seaport. / CIF Prices New Delhi ( Shipment by Air / Sea to be clearly mentioned ) Agency Commission payable to Indian Agent as percentage / annuity ( NIMR will pay the Indian Agent in Indian Rupee only after satisfactory installation and commissioning of the Equipment- Agency commission is calculated from the Ex works Price. ) Or Total cost of the Basic Equipment / System ( In case of Indigenous offers- Tenderers should quote without excise duty as this institution is exempted from payment of excise duty under notification 10 / 97 ) Ex Works Prices Cost of packing, forwarding, freight, insurance charges etc. upto New Delhi. Sales Tax/VAT Cost of Each Spare / Part / Accessory Banking Charges ( in case of Imports ) In case of Letter of Credit : Banking charges inside India and Outside India ( To whose account to be clearly indicated for Establishing LC ) Confirming Bank’s Address if any, to be clearly indicated In case of Telegraphic Transfer / Swift Transfer: Address of Banker with Account Number and Swift Code Training costs ( if any ): In India / Abroad. (Please indicate place, duration and number of persons included for training ) Additional Information Sl. No. Item 1 Payment Terms 2 Delivery Period 3 Installation and commissioning 4 Country of Origin 5 Port of Shipment ( By Air / Sea to be clearly indicated ) 6 Net weight of The Equipment and Gross Weight after Packing 7 Net Dimensions of The Equipment and Gross Dimensions after packing ( with number of packages ) 8 Company Name and Address on whom the order has be placed 9 AMC Charges Per Year after Warranty Period of 3 years comprehensive & 2years noncomprehensive Terms of Tenderer Signature of Tenderer Category - A Annexure - I Specification and allied Technical Details S.N. Name of Equipment Qty Required 7 Specification 1. Auto clave Capacity: 50 - 60 litres • Vertical, Inner chamber, made of stainless steel sheet of SS-304 grade with Service Baskets. • PID Controller to set Temp., Time • Working pressure at least 15 psi •Working temperature range must be 1200C or more Automatic Pressure control with radial lock Automatic Sterilization cycle Safety device for Over Temperature, Electrical Leakage and Over Pressure Chamber Volume: 600 Lit or more Temperature Range : 15-500C Temperature accuracy : ± 0.10C Digital timer : 1 minute to 99hr 59 minutes Material : Internal/ External -stainless steel Shelves: Stainless steel Others : Microprocessor PID control / Auto-tuning /Calibration Safety Device for Over Temperature and Electrical Leakage 2. BOD incubator 2 3. Pipetting robot 1 Automated pipetting system with multiple position deck and thermo mixer. Performance of pipetting in the range of 1μl to 1000μl with single and multichannel dispensing tools. Mixing amplitude 3.0mm or less with frequency in the range of 300-3000rpm, temperature homogeneity < 10%. 4. Centrifuge (Table top) 3 Microprocessor Controlled with Brushless drive motor. LCD Display of RPM, Time, RCF, Over speed protection, Door Interlock, Imbalance protection Maximum Speed: 15000 RPM Autoclavable fixed angle rotor, 12 x 1.5 / 2.0ml Rotor & 18 x 0.5ml Rotor with Adapter of 0.2ml 5. Centrifuge 1 Microprocessor controlled, Brushless Drive Motor Maximum Capacity: 4 x 500ml Max RPM: 5,000rpm, Max RCF: 4,300 x g Swingout Rotors for 32 x 15ml, 8 x 50ml and Plate Rotor. 6. Centrifuge (Refrigerated) (1) 7. Circulatory water bath 4 Additional Features desired: - Over speed Protection, Door Interlock, Imbalance Protection etc. Timer: 0 ~99 min. LED Digital display of Speed and Time. Microprocessor controlled Refrigerated Centrifuge Standby Cooling & Rotor pre cooling facility Noise Level< 65dB Max. RPM: 20,000rpm Max. Capacity: 4 x 750ml Brushless maintenance Free Induction Drive Motor. Features like: Imbalance Protection, Door Interlock, Over speed Protection, Adjustable Braking System Autoclave Rotors Like Swing out Rotor, Plate Rotor & Angle Rotor . 8. Photoperiod simulator 10 9. Data logger system (lan module & software) 1 Digital PID Controller Over Temperature protection, Alarm, Timer, auto-tuning, in-built temperature calibration function. Temperature range : 4°C ~ 90°C Temperature stability: ± 0.05 K Pump pressure: 0.02 bar Capacity : 12/ 24 ltr Temperature controller - PT-100 Made of corrosion resistant stainless steel Controller: Microprocessor based Display: Digital LED Display with timer Cycle: Programmable dawn & dusk condition for 90 minutes duration Load: 1200 W (100 W 12 val) Additional: Battery Backup Sensor – Cobalt based probe Counter – Digital temperature and relative humidity sensor. Memory – 2x1500 measuring point. Temperature Range – (-)550C – (+)1230C Relative Humidity – 0-100% Receiver – Radio serial port with 900 m antenna range 10. Data logger module 2 11. Deep freeze (-20 0 ) 8 12. Electronic Balance 5 13. Electrophoresis apparatus with power supply 6 14. Electrophoresis power pack 2 15. ELISA reader with washer 1 Software – LAN compatible software for single used Sensor – Cobalt based probe Counter – Digital temperature and relative humidity sensor. Memory – 2x1500 measuring point. Temperature Range – (-)550C – (+)1230C Relative Humidity – 0-100% Microprocessor Controlled, upright Microprocessor-based temperature control system, Programmable range from -160C to -250C. At least 310 liters Capacity Front opening lockable door with handle The Controller should be at the Eye level for ease of Digital Temp. Display. Audible and visual alarm for:High or low temperature, Power failure, Door Open, system failure. Unit with castor for easy movement. Maximum capacity at least 100g Readability 0.01mg Linearity 0.03mg Repeatability: 0.01mg It should be provided with protective in-use cover including permanent shock and overload protection. 15/15 cm gel tray, with comp options ranging from 1 to 30 samples comb of 1 mm thick, and 2 mm thickness. Four comb slots – at 3.5 cm intervals along the tray for faster separation 7x15 cm gel tray with comb option of 8 and 10 mm well 1 mm and 2 mm thickness. Colored loading strips-for well detection when loading UV-transparent acrylic casting tray Slide handles Power supply: No. of outputs= 2; Voltage: up to 300V, IV steps; Current: 1-400 mA,1 mA steps power: max 120 W Output 600V, 2.5 Amp, 500 W, output range programmable 10-500 V Output terminals: 4 pairs recessed Volt/Hour Control Spectral Range: 400-750nm Readout Range: 0-3.5Abs Accuracy: +/- 2% , not more than 0.008 Abs Precision: CV< 0.5 % , not more than 0.008Abs Linearity: +/- 2% or 0.007 Abs Filters: 8 slot filter wheel with 3 filters Half Band width of Filters : 3-9nm Reading Speed: Not more than 6 seconds entire 96 well plate, Plate Movement: Selectable Continuous Mode as well as Stepping mode Interface Connections: Serial RS-232 interface & parallel printer interface, Shaing: Linear Shaking , 3 speeds Key Pad: 30 keys with click action switches Display: 2X20 character alphanumeric LC display Optical System: Quartz Tungsten Halogen lamp ( 8V/50W) Onboard software: Single/dual wavelength endpoint, single wavelength kinetic, two point measurements. Ranged , Greyscale , threshold, point to point, Linear Regression , Cubic Spline, Cut off calculations. Onboard memory: Minimum 64 assay protocols, retained blank & retained curve fits. External software: Windows based software – for operation and data reduction for use with external computer to control reader. Printer: External Power Source: 200-240V, 50Hz. Consumption of 170VA Max. Wash heads: 8 or 12 way Coaxial wash head Wash Volume: 50-750ul in 50ul increments Residual Volume: <5ul per well Programming: Program Cards, Liquid Level Sensor in Waste Bottle Both Reader and washer should be IVD compliant. 16. Fluorescent Microscope 1 17. Fogging machine (A=Thermal Fogger B= Cold Fogger) 2 Infinity corrected Harmonic Compensation optical system Upright Research Microscope with mech. Tube length 200 mm parfocal, 12v 100W Halogen illumination Trinocular Head with Binocular phototube FOV1~22 mm with 10x Pair focussable Objectives: for bright field & fluorescence application- Objective Achromat 10x , 20X, 40X& 100X OIL Interchangeable nosepiece, super hard coated surface rectangular mechanical stage with low positioned coaxial x and y motion control Universal condenser LED High intensity Fluorescence Illumination with Fluorescence Intensity Control to decrease light intensity Epifluorescence filter cube for FITC/GFP, TRITC/Texas Red and DAPI. Scientific DIGITAL CAMERA SYSTEM, capable of handling brightfield, fluorescene,dic darkfield images, approx. 3.00 million pixel resolution with large pixel size- 2.7x2.7 micron Image Acquisition and Overlay software Specification “A” Fuel Consumption : 1.6-1.8 liters / h Spraying Capacity : 5-40 l / h Spray Smoke Range : 10-20 m Water Fog range : 7-9 m Fog particle diameter : less than 30 microns Container Capacity : 6.0 liters Fuel Tank Capacity : up to 2 liters Tank Pressure : 0.12 ~ 0.15 bar Start Power : 2 * 1.5- volt batteries on the 1st Specification “B” DISPLACEMENT - 56.5 cc ENGINE POWER - 2.6 kW FUEL CAPACITY - 1500 cc CONTAINER CAPACITY - 14 liters SPRAY RANGE (MAXIMUM) - Vert.: Horiz.: SOUND PRESSURE RATING - 75 dB(A) 11.5 m 12 m 18. Flow Cytometer 1 19. Gel documentation system 3 The system should be able to provide quantitative information like Dot plots, histograms and statistical data for large cell populations. The system should have 3 solid state lasers (Blue 488nm, Violet 403-405 nm and Red laser 633642nm). The system should be capable to upgrade in future (opt) The system should be capable of doing studies like Cell cycle analysis, Immuno-phenotyping, Intracellular cytokines estimation, cell death analysis etc. Must perform 9 or more fluorescence parameters along with forward and side scatter simultaneously. The system should have at least sensitivity of 100 MESF. The system should have a feature of compensation capability between all fluorescence channels manually and through auto compensation as well as post acquisition compensation. Must have sample acquisition rate of least 20,000 events per second or more. The system should have automated instrument start up, cleaning and shut down procedures. The equipment must have provision for through rinsing of the sample probe. The instrument should be open and running user friendly protocols for immune-phenotyping like no lyse /No wash protocols for immune-phenotyping with peripheral blood. Data from the cytometer should be exportable and can be analyzed on offline software. Software: PC or Mac based software; capable of both online and offline analysis. Software should display and control instruments processes. The instruments should be available with at least two user license software. On-line UPS with 30 minutes backup of appropriate electrical specification suitable for the flow cytometer must be quoted. The vendor should have an Application and technical support facility for prompt and efficient application and service support of the instrument after purchase. Comprehensive on-site warranty for two years + 3 Year extended warranty along with cleaning solution, sheath fluid, calibration beads & tubes to do 1000 samples. The company should provide the start up kits (mouse and human) to demonstrate all the application including flurochrome labeled antibodies and dyes to do 1000 samples etc. Versatile Gel documentation system to support wide range of applications like- Fluorescent dye, 2D, 1-D, Dot Blotting, Nucleic acid detection, Densitometry etc. Should have true 12 bit CCD camera with image resolution greater than 4 megapixel. Pixel size: 4.65 x 4.65 um. Image acquisition with automatic focus and iris adjustments for all compatible applications. Dynamic range of more than 3 orders of magnitude. Dynamic flat fielding for higher reproducibility. Sample size should be of minimum 28 X 36 cm. Should have motorized zoom lens- f/1.2, 12-75mm. Publication ready images with capability to define dpi and size. To be supplied with standard PC and PC compatible software 20. Gel Rocker 1 21. Hot Air Oven 2 22. Incubator 2 23. Incubator 1 Speed settings: Motion: Platform dimension: Timer Range 35 rpm in various steps Tilt 290(W) x 200(D) mm up to 3 hrs or continuous Microprocessor controlled with Air Convection, Temperature range ambient +10oC to 250oC ± 0.2oC thermostatically controlled, Volume: 300 Liters or More, Volume optimized temp control with PT-100-sensor, Big LED read out, Automatic ON-/OFF-timer function (99.59 h.min), Two or three adjustable shelves, Power Supply : 220V/50 Hz, Over Temp. Protection safety device, Safety device for over temperature and electrical leakage Capacity: 100 lit Interiors: Easy to clean, stainless-steel interior (AISI 304) Temperature Control: Microprocessor based Temperature Range: 5°C above ambient to 50°C Temperature Uniformity: +/-0.6 (Fan off) and between ±0.2°C and 0.4C (Fan full speed) Temperature stability: ±0.1°C (measured at 37°C) Display: Large, easy to read fluorescent display Additional: Internal glass door allows sample viewing without impacting temperature Continuously –running condensed unit Refrigeration: Hot gas bypass system Audible alarms and visual indicators Extended temperature/humidity ranges availability convenience receptacle 5°-44°C (±0.5°C) lights on and 2°-44°C (±0.5°C) lights off Controller to control temperature, humidity Monitoring system Light intensity: upto 115 umol /m2 /s Access Port with cover 24. Laminar flow 3 25. Liquid Nitrogen Container (Big) 6 26. Liquid Nitrogen Container (small capacity) 4 Self-contained water-cooled condensing unit Class II type A2 design with two HEPA Filters, efficiency of 99.993% at 0.3um particles. Cabinet air circulation:70% of total air re-circulates within the cabinet and 30% of air vent through HEPA Filter to ambient. Controller display should be Back Light LCD Speed Controller should be 9 Step air velocity control from 0.3~0.6m/sec. Chamber Area should be should be (W x D x Hmm) : 1200 x 530 x 680 Inner, of stainless steel 304 (AISI 304) Should have 5mm thick tempered safety glass. Should be supplied with stand with caster (BSC Class II Type A2). Sterilization: germicidal UV lamp with timer. Lamp FL 30W x 2ea Liquid Nitrogen Storage Container: Liquid nitrogen capacity: / 110-120 lit Evaporation per day: 0.60- 0.70 lit Static holding time: more than 190 days Neck Diameter: 215 mm No. of SS Racks: 4 should be provided No. of Stages/rack: 9 Storage Capacity: 3,600 (2ml cryo vials ) with moveable wheel base. Effective LN-2 Capacity: 6.5 lit Absorbed Liquid nitrogen: 4.8 lit Daily Evaporation Rate: 0.13 lit Storage Capacity: 84 (2 ml Cryo vials) OR 27. Microscope Compound ?? 6 Microscope with infinity color correction with harmonic compensation optics, with 12V, 35W?illumination source halogen Ceramic coated mechanical stage, field diaphragm Binocular phototube inclined at 20 degrees with light path distribution of (50/50). The observation tube should support field No of 22mm or higher. Plan Achromat Objective 10X/0.25, 20X/0.45, 40X/0.65 & 100X/1.25 Wide field distortion free eyepieces of 10X with F.O.V 22mm. Digital Camera with 10-mega pixels resolution with 2.5” LCD Screen. Camera should be fixed with HC 2.5x Photo-objectives. 28. Microscope Stereo 4 29. Microscope Inverted with Bright field, phase contrast and DIC system 3 30. Micropipettes 36 31. Multichannel pipettes 10 32. Magnetic stirrer 5 33. Micro centrifuge 3 34. Multiplex Protein Bead based Array System 1 Stereo zoom Dissecting Microscope with LED illumination for Transmitted & Reflected light illumination (Zoom Ratio of 4:1) consisting of following , Stereomicroscope body with Zoom Ratio of 4:1, Magnification 8X – 30X (using built in 1X objective and eyepiece of 10X) Widefield paired eyepieces 10x/23 Br. Foc (Focusable), eyepiece eyecups 1. 6 position nosepiece with at least 3 individual slots for DIC 2. Should have 12 V 100 W halogen lamp.Only halogen 3. Should include universal holder for Petri-dishes/slides/culture plates . Object stage for X and Y specimen movement. 4. Binocluar tube with 10X eyepieces. 5. Plane achromat with objective of 5x/0.12 and 10x/0.25, 20x/0.3 and 40x/0.5. Objectives of 10, 20 and 40 x should be capable of phase contrast and Plas DIC. 6. Microscope should have scientific camera of at least 12 bit with pixel size 6.45x6.45 µ and 2/3’’ CCD chip size. 2-20l, 10-100l, 100-250l, 0.2-2l 12 channel pipette, range 10-100 ul • Speed 100-1500 rpm • Maximum plate temperature 300°C • Corrosion resistant, ceramic coated plate • warning light while hot • CE/ISO certified Centrifuge with speed up to 15,000 rpm & RCf of 20,000 xg. Rotor to fit 24 x 1.5 ml/2ml Microprocessor-controlled, soft touch key pad Drive should be frequency controlled induction drive. Timer facility up to at least 90 minutes. Temperature range: -4 to + 40 degree C. The rotor should be autoclavable and provided with lid to attain biocontainment / Aerosol free 1. 96-well microplate based open system with ~100 multiplexing capabilities for different applications including screening of Cytokines, Growth factors, Phospho-protein, IgG Profiling, Diabetes Panel, Acute Phase Panel and Angiogenesis Panel. 2. Calibration kit should be provided to check signal output quality. 3. Relevant kit should be provided with system for IQ/OQ and monthly validation of Optics, Fluidics, Classifier and Reporter channel for ensuring the instrument is running as per specification. 4. Plate shaker should be provided for magnetic and non-magnetic beads. 5. Should have washer capable of washing both magnetic and non-magnetic assays for increased automation, higher throughput and better reproducibility. 35. Nano drop spectrophotometer 2 36. Digital pH meter 3 6. Machine must be provided with plates for easy calibration and must have easy maintenance and validation procedure. 7. All other consumables for cytokines measurement in single or in multiplex at least tenplex, against mouse and human including serum dilute must be quoted. 8. High Throughput Fluid delivery System for supplying up to 20 Liters of sheath fluid (40 plates) without user intervention. 9. Software should be of principal technology providing company. 10. A 2KVA online UPS with minimum 30 minutes backup of a branded and reputed make should be quoted as optional Detection limit: Upper limit - ds DNA 15000ng/μl, Lower limit - ds DNA 2ng/μl System should be supplied with the Software for measurement of Nucleic Acid, Proteins, Cell Sample Size: 0.2μl ~ 2μl Path Length: 1mm (Auto ranging to 0.05mm) Light Source (S): Xenon Flash Lamp Detector Type: 2048 – Element Linear Silicon CCD Array Wavelength Range: 200~ 850nm Wavelength Accuracy: 1 nm Spectral Resolution: <1.8nm (FWHM at Hg 253.7nm) Absorbance Precision : 0.002 (1mm Path) Measurement Type : <5 Seconds Software Compatibility : Windows 7 Professional (32 Bit and 64 Bit) 0~14 PH range in aqueous solution 0/0.01, 0.001 resolution. + 0.002 relative accuracy. Auto and manual calibration .1~5.points Auto/manual temperature composition 5~450 c ambient operating temperature ,5-85% none conditioning 37. PCR (Gradient) 4 38. Thermal Cycler 2 39. Pharmaceutical Refrigerator 9 Gradient 96 Microplate (Full – Skirted and semi skirted) Block Peltier Multisensor technology, Solid State Thermo electric heating and cooling Hot lid for Oil free operations Advanced PID Controller (Latest Touch screen technology) Multipurpose PCR with interchangeable Blocks System should recognize the block automatically and configures its Software automatically. Sample Capacity: 96 x 0.2ml Temp. Range: 4oC ~ 99oC Heating Rate: >4.0oC/Sec or Better Cooling Rate: >4.0oC/Sec or Better Block Temp. Uniformity: <+0.2oC or Better Block Temp. Accuracy: <+0.1oC or Better Gradient: 1oC ~ 30oC Gradient Range Across the temperature Max. Segments: 5 Program Steps: up to 16 Steps (For Touch Down & other Applications) Memory: 100 or more Programs through USB or PC Storage Max. cycles : 99 Cycles Should be controlled and programmed through PC/Data Processor Operating Voltage: 220V/ 50Hz Auto restart facility after power failure with 2KVa ONLINE UPS Optional Block like Dual Block (48 x 0.2ml & 30 x 0.5ml), Dual Block (48 x 0.2ml & 48 x 0.2ml), 384 Gradient MicroPlate Block, In Situ Block etc. should also be quoted. Thermal Cycler with 96-well for 0.2 ml PCR tubes Option for fast-PCR and standard-PCR chemistries With six independent peltier blocks to run PCR with different annealing temperature simultaneously Max ramp rate > 3.8 C/sec PCR volume range: 10-80 ul Touchscreen for programme setting and information The Medical Refrigerator should be specialized for cold storage of pharmaceuticals as well as biological products. Microprocessor-based temperature control system with automatic defrosting. Temperature Range: 2oC ~ 10oC at ambient temp of 32oC. 40. Sonicator (for large volume) 1 41. Sonicator (for small volume) 3 42. Tissue Dissociator 1 Capacity should be more than 310 Liters. It should have 4 compartments or more. Digital display of temperature. The temperature ranging from 2 To 10°C can be set freely, controlling precision +1°C with display accuracy 0.1°C. Audible/visual alarm system in case of high or low temperature condition, sensor abnormality, door open and power failure to ensure the safety of storage material. Double deck glass door, inert gas inside, equipped with special lock. Four Castors at the bottom for easy movement. Ultrasonic processing for sample volumes from 100-500ml with variable probes, with LCD digital display for sample temp, Model should be reliable and cost-effective option for cell analysis DNA shearing, protein extraction, bacterial cell lysis and mixing applications. Option of various amplitudes 2, 3, 8, 12, 15, 18. a) Benchtop Model, with purpose built sound insulated chamber, self contained unit with digital display. b) Should have a range of at least 3 interchangable titanium probes (Exponential and Solid) ideally suited for volumes 10µl -10 ml and continous flow. c) Should have high frequency generator with piezoelectric transducer d) Should have 0- 99 minute timer with override switch facility. e) Must be supplied with process timer unit and watage/Amplitude meter. f) Must be supplied with exponential microprobe and solid probes, batch treatment and continous flow vessels and also with tubes and sealing caps etc. Homogenization of tissues for molecular applications Single-cell suspensions from tissues for cell separation, cell analysis, and cell culture Standardized procedure High Level of user safety Sterile sample handling Specific Software for the dissociation of tissues to obtain single- cell suspensions Specific Software for the homogenization of tissues or cells to isolate biomolecule At least two samples in parallel can be processed. Power consumption: 320 VA Rotational Speed: 200- 4,000 rpm Specific tubes (2 packes of each) must be provided to demonstrate the function of machine 43. UV spectrophotometer 1 44. UV spectrophotometer with PC & Printer 1 Truedouble beam Spectrophotometer Diverse measurement modes including – wavelength scan, time scan, multi wavelength measurement etc.; Fast wavelength scan over the entire wavelength range with maximum – scan speed of 1500nm/ minute Wavelength range : 190 -1100nm; Spectral Bandwidth : 1.5 nm Stray Light: <0.05%( 220nm Nal, 36nm) Wavelength Accuracy: minimum ±0.3nm Baseline Stability: ±0.001A Photometric Range: 0-200%T, -0.3-3A Light Source: Xenon or deuterium and tungsten. Memory should be more than 1000 Display : Absorbance, Transmittance and concentration. Display should be on color touch screen. Standard single cell holder for 500ul, and 50ul quartz cuvettes Quartz cuvettes should be provided to demonstrate the function of machine Built in Software for Different applications such as DNA/RNA Analysis mode; Protein Analysis Mode with kinetic measurement, quantifications, Concentration Values etc; True double beam Spectrophotometer Diverse measurement modes including – wavelength scan, time scan, multi wavelength measurement etc.; Fast wavelength scan over the entire wavelength range with maximum – scan speed of 3000nm/ minute Wavelength range : 190 -1100nm; Spectral Bandwidth : 1.5 nm Stray Light: <0.05%( 220nm Nal, 36nm) Wavelength Accuracy: minimum ±0.3nm Baseline Stability: ±0.001A Photometric Range: 0-200%T, -0.3-3A Light Source: Xenon or deuterium and tungsten. Memory should be more than 1000 Display : Absorbance, Transmittance and concentration. Display should be on color touch screen. Standard single cell holder for 500ul, and 50ul quartz cuvettes Quartz cuvettes should be provided to demonstrate the function of machine Built in Software for Different applications such as DNA/RNA Analysis mode; Protein Analysis Mode with kinetic measurement, quantifications, Concentration Values etc; Thermal gradient for melting studies (nucleic acids) with heat and cool peltier compartments with supportive software 45. Vortex 4 46. Vertical Autoclave (Heavy duty) 1 47. Vacuum pump 2 48. Shaker water bath 2 100 to 3000 rpm • Orbital diameter: 4.5mm • Variable speed control • Supplied with cup attachment. One hand attachment, one hand insert, Micro tube insert Corrosion resistant heavy base casting for stable work surface Capacity should be 100 liters Direct heating by Stainless Steel in colony Heater Should have Stainless Steel Perforated basket Sterilization temp. up to 123ºC with fully automated sterilization cycle. Accuracy <+ 0.5 oC at 121.0oC Digital PID Control with pt – 100 sensor, Timer and Auto Tuning. Fully Automated Safety Feature for over temperature and electrical leakage. Mechanical over pressure safety valve. Dual LED displays present temperature and set temperature or remaining time simultaneously Power supply 220V, 50 Hz Vacuum pump A chemical-resistant diaphragm vacuum pump Displacement capacity of pump: at least 35 litres/min Vacuum of minimum 2 mBar that is designed to be used with acids and low and high boiling point solvents. Temp. Range: Ambient +5oC to 99oC Digital microprocessor controlled. Minimum 30 litres capacity. Shaking speed should be 20 ~ 120 rpm/ 25mm stroke reciprocal motion/+1rpm Should have Digital LED display PV and SV value and selection of Temperature, speed and time display. Temperature and shaking can be controlled together or independently with wait off timer. Silent, Low noise level belt drive shaking mechanism. 49. 2-D Gel Electrophoresis System 1 Acceleration and reduction speed rate is adjustable Corrosion resistance seamless stainless steel 304, Internal bath gables lid Over temperature cut – off, electrical leakage breaker including stainless steel 304 Universal spring rack to accommodate various kinds of containers including stainless steel (304) lid. First Dimension Must include Basic IEF Unit with inbuilt Power pack, and Accessories and Instructions. System should be capable of running 12 or 24 IPG strips of various lengths like 7, 11, 17, 18, and 24 cm in the single system over a wide pH range ( pH 3-10, 4-7, 3-6, 5-8, 7-10) and narrow pH ranges (3.9-5.1, 4.7-5.9, 5.5-6.7, 6.3-8.3) simultaneously. Must be capable of 4 lane digital display for all functions for running the system and samples. Completely preloaded programmable operation Control panel: 12 key alphanumeric keypad with 4 soft-keys and 3 function keys. Programmable Parameters Rehydration and focusing time, platform temperature, current limit per IPG strip, Voltage and Voltage ramping time for each step Voltage, Ramping Profiles Slow, Linear or Rapid Data Collection:RS-232 serial port and optional thermal printer. Voltage output range 50 - 10,000 Volts with 10 V increments. Must be capable of Current (0- 2.4 mA with 0.01 mA increments) detection, of no load, overload, load surge, ground leak, short circuit over voltage protection autopower resume option after power failure available Must have a Peltier cooling plate for efficient heat dissipation ( maintain temperature of 10-250 C) Must be supplied with Focussing trays with lids ( 7, 11, 17, 18, and 24 cm), and Rehydration and equilibration trays with lid ( 7, 11, 17, 18, and 24 cm), foreceps, pack of electrode wicks, mineral oil , & cleaning brushs. Second Dimension (SDS PAGE System) Must Includes Lower Buffer Chamber, Upper Buffer chamber, Central Cooling Core with laminated Gaskets, lid with Power Cables, sets of Glass plates of different sizes plate separating tools, Sandwich Clamps, Casting Stand with Gaskets, Leveling Bubble. Heat exchanger, spacer mate alignment template. Must include clamp assemblies, thick spacers and combs of different sizes Dual gel casting stands with leveling base. Power Pac Universal Digital Display:128x64 pixel, yellow-green, backlit graphics LCD output range (programmable), Volt: 5-500 V, Current: 0.01-2.5 A, Power: 1-500 W, Type of output: Constant voltage, constant current mode with automatic crossover Timer : 1 min- 99 hr, 59min Volt - hour control Must include Pause/resume function and Editing on the fly Must include Temperature Control, Data transfer/ archiving, 4 recessed port in parallel Safety Features: lead detection; sudden load change detection; ground leak detection, arc detection, overload/short circuit detection; overvoltage protection. Must have Automatic recovery after power failure. 2D Software Must include 2-D Analysis Software with personal computer suitable for analysis and data basing of 2-Dimension gels/blot, X-ray films, storage phosphor images and microarray slides. Software must include capabilities to analyze complex 2-D gel patterns having capability which allows us to analyze databases of up to 1,000 gels. Must have abilities, to align gels quickly and properly the first time, every time. Must include sophisticated algorithms which ensure that sports are correctly matched, with little or no editing. Must have accurate spot detection wizard and sophisticated Quantitation (Protein spots identification). Software must include automated detection and Gaussian modeling that have capability of separation of merged, overlapping spots to eliminate the need of manual intervention, ability to normalize among gel images for more accurate comparative results Must include Replicate Group Consensus tool allows spot matching information across replicate gels to be leveraged to find and correct spot detection errors" Must include Sophisticated statistical analysis tools to identify experimentally significant spots Must include Intuitive data mining tools to help user to identify expression outliers and Boolean queries to allow multiple analysis results to be combined and compared. Wicoxon paired-sample algorithm for statistical comparison of sample pairs. Must include sample classification database: unlimited number of samples classes can be defined and their attributes assigned or imported from external sources. Must include system high quality 2D image scanner with modes transmittance and reflectance with optical resolution 1600 x 3200 dpi, interpolated resolution 12800 x 12800 dpi, resolution 16 bit grey levels, 48 bit color with maximum gel size : 202 mm x 253 mm. Must include Interface fast SCSI, USB with scan optical density range: 306 OD and power input: 100-240 V 50. Vertical gel electrophoresis unit with electro blotting and power pack 1 Electrophoresis system complete set with combs, plates, and casting accessories for 10-well and 15 well, 0.75 mm and 1.0 mm thick gels, should be able to run 2 gels simultaneously (10 x 8cm) Color-coordinated cassettes and electrodes of the gel during transfer Should supply with Ice cooling unit to absorb heat generated during rapid transfers Power supply unit (microprocessor controlled) 600V with LCD display and input power of 220V and timer Should have at least two anode-cathode Output should be adjustable in the form of constant voltage, current, or power with automatic crossover. Should have pause and resume function Should supply extra 20 sets of glass plates with 1.0 mm Integrated Spacers. Semi dry electro-blotting unit for transfer of electro transfer of four gels within 45 min. Membrane Feeding System :- Possible to modify the meal by the introduction of chemical of infectious agents and precise temperature maintenance. Feeder Unit: - The durable plastic body houses accurate, electronic temperature control and is fitted with cable plugs. Meal reservoir should be removable and autoclavable. Operating temperature of each feeder should be adjustable and should have electronic thermometer with a resolution of 0.1 oC. Feeding Membrane:- The collagen membrane size approximately 6x6 cm. Power Unit:- Should be portable and operated on 220v/ 50 Hz. Simultaneously power up to 5 feeders. Supplied with a power cable at least 2 meter long, cable should have extension to reach cages distant from main socket. Meal Reservoir:- The capacity of reservoir should be maximum 5 ml with at least 10 sq. cm. feeding area To range of dispensing the large volumes of solvents from 1ml-1 litre. 51. Membrane Feeding Apparatus 4 52. Bottle top dispenser (1-100ml) 3? 53. Nitorgen gas cylinder 1 Carbon steel material with brass valve, 46.7 litr capacity 7 cu.m gas quantity with 130-150 kg/cm2 pressure 54. Shaker 1 Microprocessor controller set for accuracy and reproducibility temperature. Brushless DC Motor provides low noise, no vibration and reliable. Selectable display of Temp. Speed, time and State of Power failure 55. Auto nanolitre injector with universal adaptor and micro manipulator support base 1 Each mode shown by LED indication like temperature, speed, time and state of power failure. Reciprocating shaking speed 25 to 340 RPM Stroke 30mm for orbital shaking Artificial intelligence system which maintains precise speed and time control by using MICOM. Possible to operate in cold chamber & incubator Easy changeable platform. Should be able to operate either continuously or up to 48 hours. To handle various capacity of Flask 36 x 100 ml 23 x 250 ml 16 x 500 ml 9 x 1000 ml 4 x 2000 ml Possibility of using Tubes & Flasks on the same platform with spring mix rack. To be operated at 220V/50Hz. Automated microprocessor controlled microinjection pipet delivering precise nanolitre volumes accurately,selectable operating speeds (fill, injection and empty speed), Should be supplied with sufficient borosilicate glass capillaries injection tips, standard softening point 780C, should be supplied with universal adaptor and micromanipulator support base, Should have four color multiplex detection factory calibrated for SYBR, FAM, HEX, VIC, ROX, Cy5, Should be able to perform fast PCR cycling delivering 40 cycle PCR in <40 mins Should beflxible, easy to use software conforms to MIQE guidelines 56. Microwave 2 20 litr capacity, 1100 V, Digital display 57. Battery operated incubator 1 12Vdc, operating range 30-50C (+-0.5C),: accuracy 0.5C@ 37C, other power source options include 12 Vdc rechargeable, 12 hrs of operation , vac battery eliminator. Capacity: 6 P/A bottles or 50 mm petri dishes. Accuracy +-0 .1C@20 C, culture incubator power supply, rechargeable 12 volt battery. 58. Stratacoolers 4 -20C, temp range between-20 and -15C for upto four hrs. Polycarbonate holds twenty 1.5-2.0ml centrifuge tubes or cryovials. Printed grid, keyed lid, locking handle, non-skid feet.