MEDIA RELEASE FROM THE 2015 LUSH PRIZE EMBARGOED UNTIL November 20th, 2015 Lush Prize Awards Over $650,000 to Replace Animal Testing with 21st Century Technologies The future of animal-free science received a monumental boost this week with a record total of $690,000 (£450,000) funding by the Lush Prize, the largest prize fund for the complete replacement of animal experiments. Scientists and campaigners from nine countries share the prize money and will receive their awards in London on Friday, November 20th. The winners were selected by an international panel of experts from 51 shortlisted science teams, organizations and individual researchers. The Lush Prize – now in its fourth year – usually provides $385,000 (£250,000) annual funding to projects working to end animal research in toxicology (chemical testing). The Prize is completely funded by Lush Cosmetics. The North American branch of the global cosmetics company added another $305,000 (£200,000) to the prize pot this year. The prize fund rewards work in areas of science, training, public awareness, lobbying and young researchers. For the first time, this year also awards five Black Box Prize winners for their work in mapping the world's first 'human toxicity pathway', fully explaining at a molecular level how a toxic chemical can enter the human body and lead to a recurring allergic skin reaction. Prof Michael L. Shuler and team at Cornell University This year Michael L. Shuler, Former Chair of the Department of Biomedical Engineering at Cornell University, and team are recognized in the Science category for their work in developing new standards of toxicology testing that can replace animal testing. Shuler has partnered with UCF researcher Dr. James J. Hickman, Professor of NanoScience Technology, Chemistry, Biomolecular Science and Electrical Engineering at the UCF NanoScience Technology Center. They are awarded for developing Body-on-a-Chip systems, operated with tissues derived from human cell sources, and are capable of simulating the human metabolism including toxic side effects. They can play a significant role in determining the success of new pharmaceuticals without the use of animals. Shuler’s team consists of: Mandy B. Esch, Assistant Professor, Syracuse University, Gretchen Mahler, Assistant Professor, Department of Biomedical Engineering at SUNY Binghamton and Tracy Stokol, Associate Professor Department of Population Medicine and Diagnostic Sciences, College of Veterinary Medicine at Cornell University. Professors Esch and Mahler did much of this work while at Cornell University. Hickman and Shuler are utilizing Hesperos, a startup biotech research and development company, to commercialize the technology. Dr. Shuler is President and CEO and Dr. Hickman is Chief Scientist at Hesperos. “Body-on-a-Chip systems can play a significant role in determining the efficacy and toxicity of new pharmaceuticals without the use of animals,” Dr. Shuler explained. Aside from the ethical considerations of using live animal subjects to test potentially life-saving drugs, animal testing is woefully inaccurate. For every 50 drugs that are determined to be safe for animals, only one proves safe and efficacious in humans,” Dr. Hickman said. About the Lush Prize A joint project between cosmetics company Lush and research group Ethical Consumer, the Prize is designed to drive forward the complete replacement of animals in experiments, particularly in toxicology (chemical testing) research. Lush Prize judges believe that mapping this pathway, using 21st century technologies like genetics and computing, represents a breakthrough into a future where a superior molecular science replaces the old, imprecise technology of testing on animals. Lush Prize has now provided a total of $1.874 million (£1.2 million) to end animal testing. ENDS PRESS ENQUIRIES Lush Fresh Handmade Cosmetics US Public Relations: Mandy Kirschner mkirschner@lush.com (347) 277-0943 Krystina Puleo kpuleo@lush.com (212) 965-0161 Crystal Carroll ccarroll@lush.com (604) 749-0843 NOTES TO EDITORS The complete list of winners is below. The Lush Prize is a partnership between Lush and Ethical Consumer to support animal-free toxicology and is designed to reward groups or individuals working in the field of cruelty-free scientific research, awarenessraising and lobbying to help bring an end to animal testing. The £250,000 annual prize fund (boosted this year by an extra £200,000) is the biggest prize in the non-animal testing sector, and the ONLY one to focus solely on the replacement of animal tests. It seeks to focus pressure on safety testing for consumer products in a way that complements projects already addressing the animal testing of medicines. The Prize categories (http://www.lushprize.org/awards/) Public Awareness: public awareness-raising of on-going testing Science: for the development of replacement non-animal tests Training: training researchers in non-animal tests Lobbying: policy interventions to promote the use of replacements Young Researcher: to researchers under 35 years old specialising in replacements research Black Box: for a key breakthrough in human toxicity pathways research About Ethical Consumer: Ethical Consumer Research Association is a not-for-profit research and consultancy co-operative specialising in independent research into social, animal welfare and environmental issues. www.ethicalconsumer.org About Lush: Lush is a campaigning inventor, manufacturer and retailer of fresh handmade cosmetics with shops in 49 countries. The Lush Prize is one element in a broader campaign called 'Fighting Animal Testing'. Details of last year's prize winners can be seen at: http://www.lushprize.org/2014-prize/ Every year, it is estimated that more than 115 million animals are used in testing laboratories around the world. Lush Prize 2015 winners: Name Christophe Mas Michael L. Shuler & team Gilly Stoddart Dmitry Leporsky Bianca Marigliani Ilka Maschmeyer Elena Kummer Jeremy Caplin Lena Smirnova Laura Bray Organization Oncotheis Cornell University; Hesperos; Syracuse University; SUNY Binghampton University; University of Central Florida PETA International Science Consortium Ltd. Federal University of São Paulo Technical University of Berlin and TissUse Università degli Studi di Milano Iowa State University Center for Alternative to Animal Testing Leibniz Institute for Polymer Research Country Switzerland USA Prize category Science Science UK Training Ukraine Brazil Training Young Researcher Germany Young Researcher Italy Young Researcher USA USA Young Researcher Young Researcher Germany Young Researcher Bob Diderich Frank Gerberick Terry Schultz Andreas Natsch and Roger Emter David Basketter Mojo Mathers OECD Adverse Outcome Pathway programme Proctor & Gamble University of Tennessee Givaudan France Black Box USA USA Switzerland Black Box Black Box Black Box DABMEB Consultancy Ltd SOKO Tierschutz e.V. Beagle Freedom Project Green Party MP UK Germany USA New Zealand Black Box Public Awareness Public Awareness Lobbying