Post-course Survey
Fall 2009 BioSci 0715
MCQ
Directions:
Do not write your name or make any identifying marks on this survey or the
scantron, it is meant to be anonymous. Please generate a number known only to
you by picking the last two digits of your phone number, the first initial of your
mother's name and the last initial of your father's name. Write this number ID on
the scantron, on the short answer questionnaire and on the envelope.
This is a survey to evaluate familiarity with a topic we discussed in this course. It
DOES NOT count toward your grade. Your responses will help us design future
instruction in this course. Choose one of the items that describe the process or
role played by the term in the question, if you have some notion or familiarity
about the term. If you are unfamiliar with the terminology please omit a
response (leave the scantron bubbles for that item BLANK). Please do not guess.
1. Which item describes the role of cellular receptors in general?
a. Pores in cell membranes allow the entry of ions or charged particles
b. Antibodies attach to flagella that extend from the surface of cells
c. Cell activity is affected by hormones or growth factors.
d. Hormonal reactions are controlled by pH.
2. Which item describes the role of scaffolding proteins?
a. Cytoskeleton elements that permanently support cellular organelle
structure
b. Temporary track-like structures that facilitate vacuole
movement in cells
c. Tethers that bind interacting members of a reaction complex
together
d. Cellular support proteins that aid in the attachment of steroid
hormones to receptors just prior to transduction
3. Which item describes the process of homeostasis?
a. The inhibition of organelle movement
b. Maintaining a constant cellular environment
c. Equalizing concentration of ions on either side of a cell membrane
d. Yearly return to a nesting site by migratory birds
4. Which item describes the process of cross talk?
a. Sharing of components between different reaction pathways
b. The interaction of two ligands attached to the same receptor
c. A cell reaction that links a cytoplasm receptor to a nuclear signal
d. An exchange of genetic material from RNA to DNA
5. Which item describes the process of amplification?
a. Generating multiple copies of a protein using a very limited amount of
the desired protein and a procedure called PCR
b. A small signal elicits a large response through networks of
intracellular reactions
c. Determining the multiple relationships among members of a family
tree through evolutionary analysis.
d. Cloning a hormone repeatedly to increase its effectiveness in
generating a cellular response
6. Which statement below describes the role of c-ras?
a. Cell membrane pores provide a means to allow ions to flow into
cellular cytoplasm
b. Receptors located in cell membrane assist in the entry of steroid
hormones into the cell cytoplasm
c. Reaction pathways inside cells are maintained at a distance from
one another by small spacing proteins
d. GTPases turn off G-protein activation
7. Which of the following describes the role of second messengers?
a. Buffers maintain pH balance
b. Homeostasis in general works through an intracellular negative
feedback process.
c. Intracellular kinase activation results from direct interaction with
large hormone-like molecules
d. A small molecule or ion in the cytoplasm changes intracellular
enzyme activity
8. What item describes the role of SOS?
a. A general alarm substance released by some plants deters the entry of
disease causing microorganisms
b. Insects release pheromones to attract other insects during mating
periods in the early spring
c. Guanine nucleotide exchange factors assist in the activation of G-proteins
d. Son of Sevenless activates GTPases thus effectively stimulating the Gprotein cell mechanism.
9. What item describes the role of Grb in cellular life?
a. Cell surface projections provide links to other cells on contact
b. Antibodies attach to finger-like extensions that "grab" hormones in the
extracellular space
c. Cell surface receptors, on activation, associate with intracellular proteins
that link to other response components
d. Modulation of cellular responses requires stimulation of cellular
projections that link cytoskeleton sections
10. What item describes the role of MAPK?
a. Kinases are enzymes that phosphorylate other proteins to affect their
activity.
b. Intracellular support systems resemble a map of crisscrossing roads
similar to a road map.
c. Potassium (K) regulates intracellular activity by changing the voltage
across membranes
d. Inactivation of DNA binding proteins is necessary for transcription.
11. Which item is common to all diseases in humans?
a. Foreign bacteria invade the human body
b. Inherited mutations produce disease
c. Viral infection that uses cellular machinery to make more viruses
d. Perturbation in cellular information processing
12. What item describes the process affected by Raf?
a. Just before moving into the nucleus a key phosphatase is
dephosphorylated
b. Protein conformational change results from removing GTP from a Gprotein
c. Cell cycle checkpoints are affected by small molecules, which accumulate
in the cytoplasm over time.
d. Initiation of a cascade of kinase reactions