Complete Dominance Student Activity Name____________________________________ Class_____________________________________ Open the TI-Nspire document: complete_dominance.tns 1.2. An allele is a form of a gene. Alleles determine traits, such as eye color, skin color, and risk for certain disorders and diseases. Most offspring inherit pairs of alleles—one allele from each parent. The specific alleles that make up the pair are important to what trait is expressed as well as what can be passed to the next generation. 1.3. Although the combinations of alleles can interact with one another in different ways to express a trait, one of the most fundamental interactions is known as complete dominance. With complete dominance, a dominant allele is always expressed whenever present. Recessive alleles will not be expressed unless it is the only type of allele present in the pair. 1.4-1.5. A genotype describes the specific pair of alleles an organism has in its genetic information. It is usually described in one of three ways: homozygous dominant – both alleles in the pair are dominant. homozygous recessive – both alleles in the pair are recessive. heterozygous – one of each allele is present (one dominant and one recessive). Note: to help you remember the terms here’s what the parts of the words above mean: “homo-” – same “hetero-” – different “-zygous” – form Example: homozygous dominant ("same" - "form" - "dominant") means the alleles are the same and both are dominant 1.6. A phenotype is the trait that is outwardly expressed in the organism. With complete dominance, a dominant allele is always expressed whenever present. So, a dominant trait would be expressed as the organism’s phenotype if it had a homozygous dominant or heterozygous genotype. The organism’s phenotype would express the recessive trait if it had a homozygous recessive genotype. 1.7. Overview of this Activity. During this activity you will learn the following: To predict possible outcomes of various monohybrid crosses. To understand genotype, and how it relates to the expression of a phenotype. From: This Session Contains MSG: Math, Science, and Genetics by Shawn Schlueter. complete_dominance.tns: Page 1 Complete Dominance Student Activity Complete Dominance 2.1. Gregor Mendel described how different traits in pea plants could be bred in and out of offspring, and the probabilities those traits would be expressed, through a monohybrid cross. Mono - "one" - a single trait hybrid - "to mix" “to have multiple” 2.2. Use the sliders on the page to select a set of genotypes to cross. A cross is a mating between two organisms. As you change the sliders, look at the Punnett square and see how different crosses result in different possible genotypes for the offspring. Questions: 2.3. Of the following, which cross produced the greatest number of variations in genotypes? o o o o BB BB Bb Bb x x x x BB bb Bb BB 2.4. Which of the following crosses produce offspring where all possible genotypes match the parents? Circle all that apply. o o o o homozygous recessive x homozygous recessive homozygous dominant x homozygous dominant heterozygous x heterozygous homozygous dominant x homozygous recessive 2.5. Complete the Punnett square for the cross: Bb x bb Bb bb Bb bb 2.6. Complete a Punnett square for the cross of an organism that is homozygous recessive, with one that is heterozygous for the trait. Bb bb Bb bb From: This Session Contains MSG: Math, Science, and Genetics by Shawn Schlueter. complete_dominance.tns: Page 2 Complete Dominance Student Activity 3.1. Let’s explore how different alleles affect the genotypes, and phenotypes of offspring in pea plants similar to those studied by Gregor Mendel. 3.2. The dominant allele codes for a yellow seed color, and will be represented with an uppercase Y. The recessive allele codes for a green seed color, and will be represented with a lowercase y. The presence of a dominant allele will result in a yellow seed. The absence of a dominant allele results in a green seed color. 3.3. Activity. Select a specific cross to study. On the next page, use the arrows to select the genotypes to cross, and then answer the questions using the data from the cross. 3.4. Use the sliders on the page to select your set of genotypes to cross. Record the cross below: Cross: __________ x ___________ (student responses will vary) 3.5. Select a number of offspring. The handheld will randomly assign the cross’s possible genotypes to the offspring. Review the graph of the genotypes’ distribution across the offspring. What happens when you change the number of offspring? The numbers of offspring with each genotype will change. Unless the number of offspring is very small, the distributions of each genotype will remain similar in relation to one another. 3.6. Study the Punnett square with the expected percentages of each genotype. You can hover your cursor over the pie chart to see the actual percentages of offspring with each genotype. Questions 3.7. Is there a difference between your simulation and the number predicted by the Punnett's square? Is this significant? Why might this be the case? There is a difference, as the percentages of genotypes are not the same. The numbers from the simulation are determined at each individual cross, or mating, while the predicted percentages are based upon the probability across an entire population. 3.8. Does increasing the number of offspring cause affect the difference between actual and expected results and their similarity? As you increase the number of offspring the difference between the experimental results and theoretical results become smaller. 3.9. Think-Pair-Share. Share your explanations with a nearby student. Is there anything you would change about your explanation after sharing with another student? (Student answers will vary. Students will probably notice where actual and expected results vary from student to student with each different cross.) From: This Session Contains MSG: Math, Science, and Genetics by Shawn Schlueter. complete_dominance.tns: Page 3 Complete Dominance Student Activity 4.1. Genotype vs. Phenotype. At the beginning of this document we mentioned that a phenotype is the trait that is outwardly expressed in the organism. However multiple genotypes can sometimes result in the same phenotype. 4.2. Activity. Use the Punnett's Square on page 4.3 to look at various crosses. The pie graphs on 4.4 compare the genotypes of the cross you selected to the phenotypes expressed in a random set of 50 offspring. Use 4.3 and 4.4 to answer the questions that follow. Questions 4.5. In humans the photo sneeze reflex, when suddenly exposed to light you sneeze, is a dominant trait. After leaving a dark movie theater, a family walks outside. The mother and father sneeze, their son sneezes, but their daughter doesn't. What are the possible genotypes of the parents. Choose all that apply. o o o o both heterozygous one heterozygous one homozygous dominant one heterozygous, one homozygous recessive o both homozygous recessive 4.6. Dimples are a dominant phenotype and are easiest to see when smiling. A mother smiles at her son and you do not see dimples on her face. The son smiles at her and you see his dimples. Which of the following could be the father's genotype? Choose all that apply. o homozygous recessive o homozygous dominant o heterozygous 4.7. The dominant trait is for ear lobes to hang free, a bit of lobe hanging down prior to the point where the bottom of the ear attaches to the head. With the recessive phenotype, the lobes are attached directly to the head. In a family photo, the husband has attached ear lobes while the wife's lobes hang free. If they have children, which of the following could be the probabilities their children are born with attached ear lobes. Choose all that apply. o o o o 0% 25% 50% 75% 4.8. Some people have hair on the second (middle) joint of one or more of their fingers, while others don't. Having hair at all means that you have the dominant phenotype. Complete absence of hair is recessive. A family has 3 children. 2 have hair on their fingers, 1 child does not. What is the most probable genotypes for the parents? o o o o both homozygous dominant both homozygous recessive both heterozygous one heterozygous, one homozygous recessive From: This Session Contains MSG: Math, Science, and Genetics by Shawn Schlueter. complete_dominance.tns: Page 4