NHS Research Scotland (NRS) Conference 2015
Wednesday 28 October 2015
The Queen Elizabeth Teaching and Learning Centre
#NRSConf15
09:00 10:00
Coffee and Registration
10:00 10:05
Welcome
10:05 10:20
Keynote Address
10:20 10:40
Strategic Overview from Chief Scientist
10:40 11:00
11:00 –
12:20
12:30 –
13:30
13:30 –
15:00
15:00 –
15:30
15:30 –
15:35
15:35 –
16:15
16:15 –
16:30
Mr. Mike Stevens, Head of Chief Scientist Office
Mr. Jamie Hepburn, Minister for Sport, Health Improvement and Mental Health
Professor Andrew Morris, Chief Scientist for Scotland
Precision Medicine in Scotland – A collaborative approach
Professor Anna Dominiczak, Regius Professor of Medicine, University of Glasgow, and
Vice Principal and Head of College of Medical, Veterinary and Life Sciences
Morning Parallel Sessions
A
Trials 1: Improving Patient Care
B
Trials 2: World Class Research
C
Stratified Medicine
D
Enhancing Research Capability through Health Informatics
E
Strengthening Links with Industry
F
Research Funding
G
Research Delivery and Support
Lunch, Exhibition & Posters
Afternoon Parallel Sessions
A
Trials 1: Improving Patient Care
B
Trials 2: World Class Research
C
Stratified Medicine
D
Enhancing Research Capability through Health Informatics
E
Strengthening Links with Industry
F
Research Funding
G
Research Delivery and Support
Afternoon Coffee
Welcome back
Mr. Mike Stevens, Head of Chief Scientist Office
Rheumatology – coming into a molecular age!
Professor Iain McInnes, Director, Institute of Infection, Immunity and Inflammation,
College of Medical, Veterinary and Life Sciences, University of Glasgow,
Closing Remarks
Professor Andrew Morris, Chief Scientist for Scotland
Trials 1: Improving Patient Care
NHS Research Scotland is committed to delivering excellence in research so that patients can benefit
from new and better treatments. This session will feature key studies across a range of funding streams
(NRS Fellow, CSO grant, HTA funded) highlighting some of the major clinical trials conducted in
Scotland and supported by NRS.
11:00 –
11:10
13:30 –
13:40
11:10 –
11:30
13:40 –
14:00
11:30 –
11:50
14:00 –
14:20
11:50 –
12:10
14:20 –
14:40
12:10 –
12:30
14:40 –
15:00
Chair: Professor Dave Newby, R&D Director, NHS Lothian
SCOT-HEART study: CT coronary angiography in patients with suspected angina due to
coronary heart disease
Professor David Newby, R&D Director, NHS Lothian and
Randomised Trials in Reproductive Health
Professor Siladitya Bhattacharya, Professor of Reproductive Medicine, Head of Division
of and Director Institute of Applied Health Sciences, University of Aberdeen
ORBIT study: Optimal management of RA patients requiring Biologic Therapy
Dr Duncan Porter, senior lecturer and honorary consultant rheumatologist, NHS
Greater Glasgow and Clyde
GEOS study: A Geospatial Evaluation of Systems of Trauma Care for Scotland
Jan Jansen, Consultant General Surgeon & Intensivist , Aberdeen Royal Infirmary,
Honorary Clinical Senior Lecturer and NRS Fellow, University of Aberdeen
Session Discussion
Trials 2: World Class Research
With our vision to place Scotland at the international forefront of clinical research, this session will
feature key studies across a range of funding streams (NRS Fellow, CSO grant, HTA funded)
demonstrating a range of high profile cross border and international clinical trials that aim to make a
positive difference to patients health within Scotland, the UK and internationally.
11:00 –
11:10
13:30 –
13:40
11:10 –
11:30
13:40 –
14:00
11:30 –
11:50
14:00 –
14:20
11:50 –
12:10
14:20 –
14:40
12:10 –
12:30
14:40 –
15:00
Chair: Dr Roma Armstrong, Acting R&D Director, NHS Greater Glasgow & Clyde
EMPOWAR study: The role of metformin in preventing pregnancy complications
Professor Rebecca Reynolds, Professor of Metabolic Medicine, Centre for Cardiovascular
Science, University of Edinburgh
REMOVAL study: REducing with MetfOrmin Vascular Adverse Lesions in type 1 diabetes
Professor John Petrie, Professor of Diabetic Medicine, Institute of Cardiovascular and
Medical Sciences, BHF Glasgow Cardiovascular Research Centre, University of Glasgow
WAKE-UP study: European collaborative Stroke study
Professor Keith Muir, SINAPSE Professor of Clinical Imaging & Consultant Neurologist,
Institute of Neuroscience & Psychology, University of Glasgow
Session Discussion
Enhancing Research Capability in Health Informatics
Scotland is recognised as having some of the best health service data in the world and a long tradition
of data linkage to measure long term outcomes in clinical trials, safety of new medical interventions and
understand patterns of health and illness across the population. With recent publication of A Health and
Biomedical Informatics Research Strategy for Scotland (April 2015) this session will explore how
Scotland is keeping pace with scientific discovery and advances in information technology and
discussion on the opportunities and challenges presented by the growing volume, variety and
Stratified Medicine
complexity of health data available.
The future of healthcare is about getting the right treatment to the right patient at the right time
11:00 – stratified medicine. Significant past investment in Scotland in electronic health records (EHRs)
through
11:10
and
translationalChair:
medicine
research,
vibrant healthcare
technology industry, positions
Professor
Jillcoupled
Belch, with
R&Da Director,
NHS Tayside
Scotland
13:30 – as the location to drive forward the stratified medicine agenda globally. This session will
explore
13:40 the current landscape in Scotland, future plans and investment including the new home of SMSIC at Queen Elizabeth University Hospital.
11:10 –
The HIC Research Data Management Platform: Provision of routinely collected medical
11:00 –
11:30
records Dr
linked
to Beggs,
genomicChief
and image
data for
multiple Medicine
research projects
11:15
Chair:
Mark
Executive,
Stratified
Scotland –
Emily
Jefferson,
Director
of
Health
Informatics
Centre
Services
(HIC) and Co-Director of
13:40
–
13:30 –
Innovation Centre
the Farr Institute of Medical Informatics @ Dundee
14:00
13:45
11:30
11:15 –
11:50
11:35
13:45 –
14:00
14:05
14:20
FutureMS: clinical, laboratory, and genomic predictors of disease activity in people with
MRC Farr and the NHS/Academic interface – how to make it work
recently diagnosed relapsing-onset multiple sclerosis: an observational cohort study
Stephen Pavis, Farr Institute (Scotland) and ADRC-S, Programme Director
Dr Peter Connick, Wellcome Trust Postdoctoral Research Fellow & Honorary Consultant
(Implementation)
Neurologist, University of Edinburgh
11:35 –
11:50 –
11:55
12:10
14:05 –
14:25
11:55 –
12:15
14:25 –
14:20 –
14:45
14:40
12:15 –
12:30
12:10 –
14:45
12:30 –
15:00
14:40 –
15:00
Acute Pancreatitis
in Scotland
Bio-markers
for gefitinib
response in oesophageal carcinoma
Damian
Mole,
Clinical
Senior
Lecturer
andConsultant
Honorary Consultant
Surgeon,
University
Professor Zofia Miedzybrodzka,
Honorary
Clinical Geneticist
and
Service of
Edinburgh
Clinical Director of Genetics, NHS Grampian
CR-UK’s Stratified Medicine Programme
The Glasgow Psychosis Clinical Information System: improving physical health
Dr
Karin Oien,
Senior
Lecturer
outcomes
in Clinical
major
mental
illnessand Honorary Consultant in Pathology, Institute of
Cancer
Sciences,
College
of
Medical,
Life Sciences,
University
of Glasgow.
Professor Daniel Smith, Professor of Veterinary
Psychiatry,&Institute
of Health
& Wellbeing,
Glasgow University
Session Discussion
Session Discussion
Strengthening Links with Industry
NHS Research Scotland sustains strategic collaborations with the world’s largest research organisations
and pharmaceutical companies. Rapid set up, active study monitoring, consistent approval times and a
single price are boosting Scotland’s profile. This interactive session will explore how to best engage with
industry and enhance the key benefits of working with Scotland.
11:00 – 11:10 Welcome: Dr Steven Burke, Industry Liaison Manager, NHS Research Scotland
13:30 – 13:40 CMT
11:10 – 11:25
13:40 – 13:55
Importance of commercial research
11:25 – 11:40
13:55 – 14:10
A new approach to feasibility
11:40 – 11:55
14:10 – 14:25
A new approach to site management
11:55 – 12:10
14:25 – 14:40
Experiences of working with industry
12:10 – 12:30
14:40 – 15:00
Session Discussion
Dr Virginia Acha, Executive Director Research, Medical and Innovation
Graham Welton, Development Feasibility Manager, Amgen
Catherine Matonti, Field Team Manager - UK Pharma R&D, GlaxoSmithKline
Professor Jeff Evans, Director of Institute / Professor of Translational Cancer Research,
University of Glasgow
Research Funding
The NIHR, Evaluation, Trials and Studies (NETS) programmes, fund valuable independent research for
health and social care decision makers and are managed by the NIHR Evaluation, Trials and Studies
Coordinating Centre (NETSCC), based at the University of Southampton. CSO invests significantly to
these funding streams (such as HTA and EME) to enable access for Scottish researchers. This session
will provide useful information and advice on accessing these specialist funding remits including
eligibility, application, assessment and contracts; and highlight successful studies using these funding
streams.
11:00 –
11:10
13:30 –
13:40
11:10 –
11:20
13:40 –
13:50
11:20 –
12:20
13:50 –
14:50
12:20 –
12:30
14:20 –
14:40
Chair: Dr Alan McNair, Senior Research Manager, Chief Scientist Office (CSO)
Research Funding Map – Overview of opportunities
Dr Alan McNair, Senior Research Manager, Chief Scientist Office (CSO)
NETSCC - funding for evaluation research in health
Chloe Gilbert, Senior Programme Manager, NIHR Evaluation, Trials and Studies
Coordinating Centre (NETSCC)
Session Discussion
Research Delivery and Support
Supporting a strong infrastructure for research in Scotland is crucial. This session will explore
improvements and efficiencies across the research journey and highlight support available to
researchers in Scotland to run efficient research studies and recruit to target.
11:00 –
11:10
13:30 –
13:40
11:10 –
11:30
13:40 –
14:00
11:30 –
11:50
14:00 –
14:20
11:50 –
12:10
14:20 –
14:40
12:10 –
12:30
14:40 –
15:00
Chair: Professor Julie Brittenden, R&D Director, NHS Grampian
Site selection: can we do better?
Dr Seonaidh Cotton, Trial Manager, Health Services Research Unit, University of Aberdeen
Feasibility and Beyond
Steve McSwiggan, Head of Commercial Research Services, TASC, University of Dundee
Facilitating Diabetes Research across the Healthcare Spectrum
Shona Brearley, Scottish Diabetes Research Network Manager
Session Discussion