Biology Name ______________________________ Computer Lab Activity MODS___________ Date _____________ Meiosis All students will need a notebook for today’s visit. You should record all information in your notebooks, when directed. Do not PRINT-OUT information; it must be HAND-WRITTEN. Instructions: 1. Click on the Netscape / Internet Explorer / Firefox / Safari icon, to sign on to the Internet. 2. Click on the “empty rectangular area” at the top of your screen. 3. Carefully type in http://biology.clc.uc.edu/courses/bio104/meiosis.htm and hit return (enter). Part II: Meiosis Copy the following into your notebook: Meiosis 1. In _______________ _______________, two parents give rise to an offspring with a unique gene _______________ from both of them -- each parent gives _______________ of his/her genes to the _______________. A _______________ is a discrete unit of information on the ______________ that codes for one protein, perhaps one of the many enzymes needed by our cells (and _______________). 2. _______________ cells (which are regular _______________ cells) have two sets of chromosomes; one set from _______________ _______________. a. For example, in humans one “1/2” set = _______________ chromosomes, so our somatic cells have _______________ chromosomes arranged in _______________ ______________. b. The two chromosomes in each pair are referred to as being chromosomes, so we could say that humans have _______________ pairs of _______________ chromosomes. c. The two chromosomes of each pair carry genes for the same trait (for example, _______________ _______________ ) at the same _______________, but not necessarily the same form of that _______________ (for example, _______________ vs. _______________ eyes). 3. An important exception to this is the sex chromosomes, the _________________ and _________________ _______________. a. Although these chromosomes pair with each other, they are not the _______________ _______________. The X-chromosome is _______________ and has genes for many _________________ with no match on the Y-chromosome. 1 b. A person with XX would be _______________ and someone with XY would be _______________. c. All the other chromosomes are called _______________. 4. Somatic cells have two sets of _______________ (2 x 22) chromosomes, and one pair of _______________ _______________. a. They are called _______________ or 2n cells. b. Thus, humans would have (22 pr + 1 pr = 23 pr) or 44 + XX (female) or 44 + XY (male) _______________. 5. Gametes or _______________ ________________ (eggs from _______________ and sperm from _______________ ) have one chromosome from each autosome _______________ and one sex chromosome (one set of chromosomes), thus are called haploid or _______________. a. Eggs and sperm have ½ of each pair (so they can unite during fertilization to make complete pairs (or a total set of 23 pr). b. Human eggs would have _______________ chromosomes, and sperm would have _______________ or _______________ chromosomes. 6. Meiosis is a _______________ type of cell division that produces _______________ with half as many chromosomes. a. The opposite process would be syngamy or _______________, which is the union of the _______________ and _______________ to restore the 2n number. b. This results in a _______________, the first cell formed by _______________, a completely new and different _______________ with unique genetic information _______________ from either ___________. c. The zygote divides and grows to form an _______________ which develops into a young organism, then an _______________. 7. The steps in meiosis are _______________ to mitosis and even have the same names. a. However, there is a significant difference in how the chromosomes _______________ _______________ initially. b. In mitosis, chromosomes line up _______________; in meiosis, the homologous pairs line up _______________ _______________ each other. c. In meiosis, this pairing process is called _______________, and the resulting homologous pair is called a _______________ in reference to the two chromosomes or a _______________ in reference to the four _______________ chromatids involved. 8. Interphase is the same in both _______________ and _______________, but in meiosis, it is followed by _______________ cell divisions. These two division processes are referred to as Meiosis _______________ and Meiosis _______________, and result in a total of four _______________ cells, each with a _______________ chromosome number. 2 Meiosis I a. In prophase I, the homologous chromosomes come together and match up (_______________) in pairs(tetrads or _______________). A baby girl is born with all the precursor _______________ ____________ she will ever have in a sort-of “suspended animation” until ____________. b. In metaphase I, the bivalents _______________ _______________, not individual _______________, so there’s a _______________ chance of which chromosome of each pair faces which pole of the cell - or goes to which daughter cell. c. In anaphase I, the homologous chromosomes _______________, and one of each pair travels to each of the two poles of the cell, reducing the chromosome number from _______________ to _______________. (Sister _______________ stay together.) d. During telophase I, two ________________ _______________ are formed. These usually go immediately into the second cell ________________ (meiosis II) to separate the sister chromatids. Meiosis II a. Like mitosis, the sister chromatids are ________________. This results in ________________daughter cells, each with an ____________ chromosome number. b. Fertilization triggers ________________, and then the sperm nucleus ____________ with the resulting egg nucleus. c. In human females, division of the cytoplasm is _______________ _______________. This provides a way of keeping as much ________________ as possible with the future egg/zygote. d. Rather than equal-sized gametes, one big egg and three smaller ________________ _______________ are formed. Interestingly, because the homologous pairs line up during Metaphase I, there is a 50:50 chance of which one of each pair will go to each of the poles of the cell (like flipping a coin, where you can get either heads or tails). Therefore, in humans with 23 pairs of chromosomes, a gamete (egg or sperm) could have 223 or 8,388,604 possible combinations of chromosomes from that parent. Any couple could have 223 ¥ 223 or 70,368,744,177,644 (70 trillion) different possible children, based just on the number of chromosomes, not considering the actual genes on those chromosomes. The chance of two siblings being exactly identical would be 1 in 70 trillion. In addition, something called crossingover, in which the two homologous chromosomes of a pair exchange equal segments during synapsis in Meiosis I, can add further variation to an individual’s genetic make-up. 3