Prof Gregory Y.H. Lip – spisak radova 1: Overvad TF, Rasmussen LH, Skjøth F, Overvad K, Albertsen IE, Lane DA, Lip GY, Larsen TB. Alcohol intake and prognosis of atrial fibrillation patients. Heart. 2013 Jun 13. [Epub ahead of print] PubMed PMID: 23766449. 2: Schlitt A, Rubboli A, Lip GH, Lahtela H, Valencia J, Karjalainen PP, Weber M, Laine M, Kirchhof P, Niemelä M, Vikman S, Buerke M, Airaksinen KE; for the AFCAS (Management of patients with Atrial Fibrillation undergoing Coronary Artery Stenting) study group.. The management of patients with atrial fibrillation undergoing percutaneous coronary intervention with stent implantation: In-hospital-data from the Atrial Fibrillation undergoing Coronary Artery Stenting (AFCAS) study. Catheter Cardiovasc Interv. 2013 Jun 13. doi: 10.1002/ccd.25064. [Epub ahead of print] PubMed PMID: 23765437. 3: Ahmad Y, Lip GY. Warfarin for stroke prevention in atrial fibrillation: time to switch? Int J Clin Pract. 2013 Jul;67(7):603-5. doi: 10.1111/ijcp.12157. PubMed PMID: 23758442. 4: Apostolakis S, Lip GY, Shantsila E. Pharmacokinetic considerations for antithrombotic therapies in stroke. Expert Opin Drug Metab Toxicol. 2013 Jun 11. [Epub ahead of print] PubMed PMID: 23750513. 5: Lamberts M, Gislason GH, Olesen JB, Kristensen SL, Schjerning Olsen AM, Mikkelsen A, Christensen CB, Lip GY, Køber L, Torp-Pedersen C, Hansen ML. Oral anticoagulation and antiplatelets in atrial fibrillation patients after myocardial infarction and coronary intervention. J Am Coll Cardiol. 2013 Jun 6. doi:pii: S0735-1097(13)02170-0. 10.1016/j.jacc.2013.05.029. [Epub ahead of print] PubMed PMID: 23747760. 6: Ng KP, Edwards NC, Lip GY, Townend JN, Ferro CJ. Atrial Fibrillation in CKD: Balancing the Risks and Benefits of Anticoagulation. Am J Kidney Dis. 2013 Jun 5. doi:pii: S0272-6386(13)00784-1. 10.1053/j.ajkd.2013.02.381. [Epub ahead of print] PubMed PMID: 23746378. 7: Huber K, Lip GY. Differences between ACC/AHA and ESC Guidelines on antiplatelet therapy in patients with acute coronary syndromes. Thromb Haemost. 2013 Jun 7;110(1). [Epub ahead of print] PubMed PMID: 23743615. 1 8: Wrigley BJ, Shantsila E, Tapp LD, Lip GY. Increased expression of cell adhesion molecule receptors on monocyte subsets in ischaemic heart failure. Thromb Haemost. 2013 Jun 6;110(1). [Epub ahead of print] PubMed PMID: 23740177. 9: Udompanich S, Lip GY, Apostolakis S, Lane DA. Atrial Fibrillation as a Risk Factor for Cognitive Impairment: A semi-systematic review. QJM. 2013 Jun 3. [Epub ahead of print] PubMed PMID: 23737509. 10: Hernández-Madrid A, Svendsen JH, Lip GY, Van Gelder IC, Dobreanu D, Blomstrom-Lundqvist C; conducted by the Scientific Initiatives Committee, European Heart Rhythm Association (EHRA). Cardioversion for atrial fibrillation in current European practice: results of the European Heart Rhythm Association survey. Europace. 2013 Jun;15(6):915-8. doi: 10.1093/europace/eut143. PubMed PMID: 23709570. 11: Kakkar AK, Mueller I, Bassand JP, Fitzmaurice DA, Goldhaber SZ, Goto S, Haas S, Hacke W, Lip GY, Mantovani LG, Turpie AG, van Eickels M, Misselwitz F, Rushton-Smith S, Kayani G, Wilkinson P, Verheugt FW; GARFIELD Registry Investigators. Risk Profiles and Antithrombotic Treatment of Patients Newly Diagnosed with Atrial Fibrillation at Risk of Stroke: Perspectives from the International, Observational, Prospective GARFIELD Registry. PLoS One. 2013 May 21;8(5):e63479. doi: 10.1371/journal.pone.0063479. Print 2013. PubMed PMID: 23704912; PubMed Central PMCID: PMC3660389. 12: Alings M, Smit MD, Moes ML, Crijns HJ, Tijssen JG, Brügemann J, Hillege HL, Lane DA, Lip GY, Smeets JR, Tieleman RG, Tukkie R, Willems FF, Vermond RA, Van Veldhuisen DJ, Van Gelder IC. Routine versus aggressive upstream rhythm control for prevention of early atrial fibrillation in heart failure: background, aims and design of the RACE 3 study. Neth Heart J. 2013 May 23. [Epub ahead of print] PubMed PMID: 23700039. 13: Ramcharan SK, Lip GY, Stonelake PS, Blann AD. Angiogenin outperforms VEGF, EPCs and CECs in predicting Dukes' and AJCC stage in colorectal cancer. Eur J Clin Invest. 2013 Apr 25. doi: 10.1111/eci.12108. [Epub ahead of print] PubMed PMID: 23683169. 14: Shantsila E, Tapp LD, Wrigley BJ, Montoro-García S, Lip GY. Receptors to interleukin-6 and adhesion molecules on circulating monocyte subsets in acute myocardial infarction. Thromb Haemost. 2013 May 16;110(2). [Epub ahead of print] PubMed PMID: 23677452. 2 15: Kiviniemi T, Karjalainen P, Rubboli A, Schlitt A, Tuomainen P, Niemelä M, Laine M, Biancari F, Lip GY, Airaksinen KE. Thrombocytopenia in Patients With Atrial Fibrillation on Oral Anticoagulation Undergoing Percutaneous Coronary Intervention. Am J Cardiol. 2013 May 11. doi:pii: S0002-9149(13)00980-6. 10.1016/j.amjcard.2013.04.007. [Epub ahead of print] PubMed PMID: 23672991. 16: Gallego P, Roldan V, Lip GY. Conventional and New Oral Anticoagulants in the Treatment of Chest Disease and its Complications. Am J Respir Crit Care Med. 2013 May 14. [Epub ahead of print] PubMed PMID: 23672179. 17: Apostolakis S, Sullivan RM, Olshansky B, Lip GY. Factors affecting quality of anticoagulation control amongst atrial fibrillation patients on warfarin:The SAMe-TT2R2 (Sex female, Age less than 60, Medical history, Treatment strategy [rhythm control], Tobacco use [doubled], Race [doubled] score. Chest. 2013 May 9. doi: 10.1378/chest.13-0054. [Epub ahead of print] PubMed PMID: 23669885. 18: Christiansen CB, Lip GY, Lamberts M, Gislason G, Torp-Pedersen C, Olesen JB. Retinal vein and artery occlusions:a risk factor for stroke in atrial fibrillation. J Thromb Haemost. 2013 May 11. doi: 10.1111/jth.12297. [Epub ahead of print] PubMed PMID: 23663383. 19: Birnie DH, Healey JS, Wells GA, Verma A, Tang AS, Krahn AD, Simpson CS, Ayala-Paredes F, Coutu B, Leiria TL, Essebag V; BRUISE CONTROL Investigators. Pacemaker or defibrillator surgery without interruption of anticoagulation. N Engl J Med. 2013 May 30;368(22):2084-93. doi: 10.1056/NEJMoa1302946. Epub 2013 May 9. PubMed PMID: 23659733. 20: Lip GY, Lane DA. Stroke prevention with oral anticoagulation therapy in patients with atrial fibrillation. Circ J. 2013 May 24;77(6):1380-8. Epub 2013 May 9. PubMed PMID: 23657131. 21: Ahmad Y, Lip GY. Preventing stroke and systemic embolism in renal patients with atrial fibrillation: focus on anticoagulation. Contrib Nephrol. 2013;179:81-91. doi: 10.1159/000346726. Epub 2013 May 3. PubMed PMID: 23652451. 22: Cangemi R, Pignatelli P, Carnevale R, Corazza GR, Pastori D, Farcomeni A, Basili S, Davì G, Ferro D, Hiatt WR, Licata G, Lip GY, Loffredo L, Mannucci PM, 3 Vestri A, Violi F; in collaboration with the ARA PACIS study group. Cholesterol-adjusted vitamin E serum levels are associated with cardiovascular events in patients with non-valvular atrial fibrillation. Int J Cardiol. 2013 May 4. doi:pii: S0167-5273(13)00789-4. 10.1016/j.ijcard.2013.04.142. [Epub ahead of print] PubMed PMID: 23651827. 23: Sørensen R, Gislason G, Torp-Pedersen C, Olesen JB, Fosbøl EL, Hvidtfeldt MW, Karasoy D, Lamberts M, Charlot M, Køber L, Weeke P, Lip GY, Hansen ML. Dabigatran use in Danish atrial fibrillation patients in 2011: a nationwide study. BMJ Open. 2013 May 3;3(5). doi:pii: e002758. 10.1136/bmjopen-2013-002758. Print 2013. PubMed PMID: 23645926; PubMed Central PMCID: PMC3646187. 24: De Caterina R, Husted S, Wallentin L, Andreotti F, Arnesen H, Bachmann F, Baigent C, Huber K, Jespersen J, Kristensen SD, Lip GY, Morais J, Rasmussen LH, Siegbahn A, Verheugt FW, Weitz JI. Parenteral anticoagulants in heart disease: current status and perspectives (Section II). Position paper of the ESC Working Group on Thrombosis-Task Force on Anticoagulants in Heart Disease. Thromb Haemost. 2013 May 2;109(5):769-86. doi: 10.1160/TH12-06-0403. Epub 2013 Mar 28. PubMed PMID: 23636477. 25: Svendsen JH, Dagres N, Dobreanu D, Bongiorni MG, Marinskis G, Blomström-Lundqvist C; Scientific Initiatives Committee, European Heart Rhythm Association. Current strategy for treatment of patients with Wolff-Parkinson-White syndrome and asymptomatic preexcitation in Europe: European Heart Rhythm Association survey. Europace. 2013 May;15(5):750-3. doi: 10.1093/europace/eut094. PubMed PMID: 23625944. 26: Lip GY. EUR Observational research programme: atrial fibrillation general registry pilot phase. Eur Heart J. 2013 Mar;34(11):794. PubMed PMID: 23614139. 27: Overvad TF, Rasmussen LH, Skjøth F, Overvad K, Lip GY, Larsen TB. Body Mass Index and Adverse Events in Patients with Incident Atrial Fibrillation. Am J Med. 2013 Apr 17. doi:pii: S0002-9343(13)00090-9. 10.1016/j.amjmed.2012.11.024. [Epub ahead of print] PubMed PMID: 23601271. 28: Guo Y, Lip GY, Banerjee A. Heart failure in East Asia. Curr Cardiol Rev. 2013 May 1;9(2):112-22. PubMed PMID: 23597295. 29: Roldán V, Marín F, Manzano-Fernandez S, Fernández H, Gallego P, Valdés M, 4 Vicente V, Lip GY. Does chronic kidney disease improve the predictive value of the CHADS2 and CHA2DS2-VASc stroke stratification risk scores for atrial fibrillation? Thromb Haemost. 2013 May 2;109(5):956-60. doi: 10.1160/TH13-01-0054. Epub 2013 Mar 21. PubMed PMID: 23572113. 30: Larsen TB, Rasmussen LH, Skjøth F, Due KM, Callréus T, Rosenzweig M, Lip GY. Efficacy and safety of dabigatran etexilate and warfarin in "real-world" patients with atrial fibrillation: a prospective nationwide cohort study. J Am Coll Cardiol. 2013 Jun 4;61(22):2264-73. doi: 10.1016/j.jacc.2013.03.020. Epub 2013 Apr 3. PubMed PMID: 23562920. 31: Lane DA, Lip GY. Atrial fibrillation: Anticoagulation for AF: can we GRASP-AF patients? Nat Rev Cardiol. 2013 May;10(5):241-2. doi: 10.1038/nrcardio.2013.47. Epub 2013 Apr 2. PubMed PMID: 23546443. 32: Gallego P, Lip GY, Lane DA. Bleeding risk during oral anticoagulation therapy for atrial fibrillation. Europace. 2013 Jun;15(6):773-4. doi: 10.1093/europace/eut061. Epub 2013 Mar 28. PubMed PMID: 23537615. 33: Blann AD, Kuzniatsova N, Lip GY. Inflammation does not influence arterial stiffness and pulse-wave velocity in patients with coronary artery disease. J Hum Hypertens. 2013 Mar 28. doi: 10.1038/jhh.2013.17. [Epub ahead of print] PubMed PMID: 23535991. 34: Dagres N, Lewalter T, Lip GY, Pison L, Proclemer A, Blomström-Lundqvist C; Scientific Initiatives Committee, European Heart Rhythm Association. Current practice of antiarrhythmic drug therapy for prevention of atrial fibrillation in Europe: The European Heart Rhythm Association survey. Europace. 2013 Apr;15(4):478-81. doi: 10.1093/europace/eut063. PubMed PMID: 23530117. 35: Lip GY. Awareness and treatment of atrial fibrillation in older adults: the present and the future. QJM. 2013 May;106(5):393-4. doi: 10.1093/qjmed/hct074. Epub 2013 Mar 23. PubMed PMID: 23525162. 36: Banerjee A, Fauchier L, Vourc'h P, Andres CR, Taillandier S, Halimi JM, Lip GY. Renal impairment and ischemic stroke risk assessment in patients with atrial fibrillation: the loire valley atrial fibrillation project. J Am Coll Cardiol. 2013 May 21;61(20):2079-87. doi: 10.1016/j.jacc.2013.02.035. Epub 2013 Mar 21. PubMed PMID: 23524209. 5 37: Chackathayil J, Patel JV, Gill PS, Potluri R, Natalwala A, Uppal H, Lavu D, Heun R, Hughes EA, Lip GY. Cardiovascular Risk Profiles amongst Women in a Multiethnic Population in Inner City Britain: A Potential Impact of Anaemia. Int J Endocrinol. 2013;2013:303859. doi: 10.1155/2013/303859. Epub 2013 Feb 19. PubMed PMID: 23509453; PubMed Central PMCID: PMC3590708. 38: Autores/miembros del Grupo de Trabajo, Camm AJ, Lip GY, Caterina RD, Savelieva I, Atar D, Hohnloser SH, Hindricks G, Kirchhof P; Comité de la ESC de Guías para la Práctica Clínica (CGPC), Bax JJ, Baumgartner H, Ceconi C, Dean V, Deaton C, Fagard R, Funck-Brentano C, Hasdai D, Hoes A, Kirchhof P, Knuuti J, Kolh P, McDonagh T, Moulin C, Popescu BA, Reiner Z, Sechtem U, Anton Sirnes P, Tendera M, Torbicki A, Vahanian A, Windecker S; Revisores del documento, Vardas P, Al-Attar N, Alfieri O, Angelini A, Blömstrom-Lundqvist C, Colonna P, De Sutter J, Ernst S, Goette A, Gorenek B, Hatala R, Heidbüchel H, Heldal M, Dalby Kristensen S, Kolh P, Le Heuzey JY, Mavrakis H, Mont L, Perrone Filardi P, Ponikowski P, Prendergast B, Rutten FH, Schotten U, Van Gelder IC, Verheugt FW. Actualización de las guías de la Sociedad Europea de Cardiología (ESC) para el manejo de la fibrilación auricular de 2010 Elaborada en colaboración con la Asociación Europea del Ritmo Cardiaco. Rev Esp Cardiol. 2013 Jan;66(1):54.e1-54.e24. doi: 10.1016/j.recesp.2012.11.001. Epub 2012 Dec 25. English, Spanish. PubMed PMID: 23506743. 39: Ruiz-Nodar JM, Marín F, Lip GY. Antithrombotic Management and Type of Stent in Atrial Fibrillation Patients Undergoing Percutaneous Coronary Intervention. Rev Esp Cardiol. 2013 Jan;66(1):12-16. doi: 10.1016/j.recesp.2012.07.018. Epub 2012 Oct 23. English, Spanish. PubMed PMID: 23485180. 40: Albertsen IE, Rasmussen LH, Overvad TF, Graungaard T, Larsen TB, Lip GY. Risk of stroke or systemic embolism in atrial fibrillation patients treated with warfarin: a systematic review and meta-analysis. Stroke. 2013 May;44(5):1329-36. doi: 10.1161/STROKEAHA.113.000883. Epub 2013 Mar 12. PubMed PMID: 23482597. 41: Apostolakis S, Zubaid M, Rashed WA, Alsheikh-Ali AA, Almahmeed W, Shehab A, Sulaiman K, Alqudaimi A, Asaad N, Amin H, Lane DA, Lip GY; On behalf of the Gulf Survey of Atrial Fibrillation Events (Gulf SAFE) Investigators. Assessment of stroke risk in Middle Eastern patients with atrial fibrillation: The Gulf SAFE registry. Int J Cardiol. 2013 Mar 4. doi:pii: S0167-5273(13)00359-8. 10.1016/j.ijcard.2013.02.003. [Epub ahead of print] PubMed PMID: 23481910. 6 42: Lip GY. Using the CHA(2)DS(2)-VASc score for stroke risk stratification in atrial fibrillation: a clinical perspective. Expert Rev Cardiovasc Ther. 2013 Mar;11(3):259-62. doi: 10.1586/erc.13.13. PubMed PMID: 23469902. 43: Guo Y, Lip GY, Apostolakis S. Bleeding risk assessment in patients with atrial fibrillation who are taking oral anticoagulants. Hosp Pract (1995). 2013 Feb;41(1):71-8. doi: 10.3810/hp.2013.02.1012. PubMed PMID: 23466969. 44: Kasmeridis C, Lip GY, Apostolakis S. A new era of oral anticoagulation in atrial fibrillation: implications in clinical practice. Hosp Pract (1995). 2013 Feb;41(1):61-70. doi: 10.3810/hp.2013.02.1011. PubMed PMID: 23466968. 45: Lip GY. Recommendations for thromboprophylaxis in the 2012 focused update of the ESC guidelines on atrial fibrillation: a commentary. J Thromb Haemost. 2013 Apr;11(4):615-26. doi: 10.1111/jth.12140. PubMed PMID: 23452133. 46: De Caterina R, Husted S, Wallentin L, Andreotti F, Arnesen H, Bachmann F, Baigent C, Huber K, Jespersen J, Kristensen SD, Lip GY, Morais J, Rasmussen LH, Siegbahn A, Verheugt FW, Weitz JI. General mechanisms of coagulation and targets of anticoagulants (Section I). Position Paper of the ESC Working Group on Thrombosis--Task Force on Anticoagulants in Heart Disease. Thromb Haemost. 2013 Apr 8;109(4):569-79. doi: 10.1160/TH12-10-0772. Epub 2013 Feb 28. PubMed PMID: 23447024. 47: Anandasundaram B, Lane DA, Apostolakis S, Lip GY. The impact of atherosclerotic vascular disease in predicting a stroke, thromboembolism and mortality in atrial fibrillation patients: a systematic review. J Thromb Haemost. 2013 May;11(5):975-87. doi: 10.1111/jth.12177. PubMed PMID: 23441593. 48: Li Y, Lip G, Chong V, Yuan J, Ding Z. Idiopathic orbital inflammation syndrome with retro-orbital involvement: a retrospective study of eight patients. PLoS One. 2013;8(2):e57126. doi: 10.1371/journal.pone.0057126. Epub 2013 Feb 21. PubMed PMID: 23437329; PubMed Central PMCID: PMC3578830. 49: Andersen LV, Lip GY, Lindholt JS, Frost L. Upper limb arterial thromboembolism: a systematic review on incidence, risk factors, and prognosis, including a meta-analysis of risk-modifying drugs. J Thromb Haemost. 2013 May;11(5):836-44. doi: 10.1111/jth.12181. PubMed PMID: 23433284. 7 50: Camm AJ, Lip GY, De Caterina R, Savelieva I, Atar D, Hohnloser SH, Hindricks G, Kirchhof P. Questionable levels of evidence in new atrial fibrillation guidelines? Reply. Europace. 2013 Mar;15(3):461-2. doi: 10.1093/europace/eus394. PubMed PMID: 23430753. 51: Camm AJ, Lip GY, De Caterina R, Savelieva I, Atar D, Hohnloser SH, Hindricks G, Kirchhof P. 'Patient choice' concept in AF ESC Guidelines: is the clinician giving up? Reply. Europace. 2013 Mar;15(3):460-1. doi: 10.1093/europace/eus386. PubMed PMID: 23430752. 52: Kalitzeos AA, Heitmar R, Lip GY. Localized retinal nerve fiber layer defects and arterial hypertension: insights into pathophysiology and perhaps an eye for detail? Am J Hypertens. 2013 Apr;26(4):454-5. doi: 10.1093/ajh/hpt013. Epub 2013 Feb 21. PubMed PMID: 23429476. 53: Agewall S, Cattaneo M, Collet JP, Andreotti F, Lip GY, Verheugt FW, Huber K, Grove EL, Morais J, Husted S, Wassmann S, Rosano G, Atar D, Pathak A, Kjeldsen K, Storey RF; On behalf of ESC Working Group on Cardiovascular Pharmacology and Drug Therapy and ESC Working Group on Thrombosis. Expert position paper on the use of proton pump inhibitors in patients with cardiovascular disease and antithrombotic therapy. Eur Heart J. 2013 Feb 20. [Epub ahead of print] PubMed PMID: 23425521. 54: Weber C, Lip GY. A happy new year 2013 for Thrombosis and Haemostasis. Thromb Haemost. 2013 Jan;109(1):1-2. PubMed PMID: 23418642. 55: Montoro-García S, Shantsila E, Tapp LD, López-Cuenca A, Romero AI, Hernández-Romero D, Orenes-Piñero E, Manzano-Fernández S, Valdés M, Marín F, Lip GY. Small-size circulating microparticles in acute coronary syndromes: relevance to fibrinolytic status, reparative markers and outcomes. Atherosclerosis. 2013 Apr;227(2):313-22. doi: 10.1016/j.atherosclerosis.2013.01.028. Epub 2013 Jan 29. PubMed PMID: 23415055. 56: Ntaios G, Lip GY, Makaritsis K, Papavasileiou V, Vemmou A, Koroboki E, Savvari P, Manios E, Milionis H, Vemmos K. CHADS₂, CHA₂S₂DS₂-VASc, and long-term stroke outcome in patients without atrial fibrillation. Neurology. 2013 Mar 12;80(11):1009-17. doi: 10.1212/WNL.0b013e318287281b. Epub 2013 Feb 13. PubMed PMID: 23408865. 8 57: Shantsila A, Lane DA, Beevers DG, Lip GY. Does obesity influence target organ damage and outcomes in patients with malignant phase hypertension? The West Birmingham Malignant Hypertension Project. Hypertens Res. 2013 Jun;36(6):546-9. doi: 10.1038/hr.2012.222. Epub 2013 Feb 14. PubMed PMID: 23407241. 58: Lip GY, Connolly S, Yusuf S, Shestakovska O, Flaker G, Hart R, Lanas F, Xavier D, Eikelboom J; ERROES Investigators. Modification of outcomes with aspirin or apixaban in relation to CHADS(2) and CHA(2)DS(2)-VASc scores in patients with atrial fibrillation: a secondary analysis of the AVERROES study. Circ Arrhythm Electrophysiol. 2013 Feb;6(1):31-8. doi: 10.1161/CIRCEP.112.975847. Epub 2013 Feb 6. PubMed PMID: 23390125. 59: Zuo ML, Liu S, Chan KH, Lau KK, Chong BH, Lam KF, Chan YH, Lau YF, Lip GY, Lau CP, Tse HF, Siu CW. The CHADS2 and CHA 2DS 2-VASc scores predict new occurrence of atrial fibrillation and ischemic stroke. J Interv Card Electrophysiol. 2013 Jun;37(1):47-54. doi: 10.1007/s10840-012-9776-0. Epub 2013 Feb 7. PubMed PMID: 23389054. 60: Marinskis G, Bongiorni MG, Dagres N, Lewalter T, Pison L, Blomstrom-Lundqvist C; Scientific Initiative Committee, European Heart Rhythm Association. X-ray exposure hazards for physicians performing ablation procedures and device implantation: results of the European Heart Rhythm Association survey. Europace. 2013 Mar;15(3):444-6. doi: 10.1093/europace/eut022. Epub 2013 Feb 6. PubMed PMID: 23388183. 61: Shantsila E, Lip GY. Recent advances in management of atrial fibrillation in patients with heart failure. Curr Opin Cardiol. 2013 Jan;28(2):197-208. doi: 10.1097/HCO.0b013e32835bd465. PubMed PMID: 23385332. 62: Guo Y, Wang H, Zhao X, Zhang Y, Zhang D, Ma J, Wang Y, Lip GY. Relation of renal dysfunction to the increased risk of stroke and death in female patients with atrial fibrillation. Int J Cardiol. 2013 Jan 29. doi:pii: S0167-5273(13)00010-7. 10.1016/j.ijcard.2012.12.099. [Epub ahead of print] PubMed PMID: 23375056. 63: Wieloch M, Jönsson KM, Själander A, Lip GY, Eriksson N, Svensson PJ. Estimated glomerular filtration rate is associated with major bleeding complications but not thromboembolic events, in anticoagulated patients taking warfarin. Thromb Res. 2013 Jun;131(6):481-6. doi: 10.1016/j.thromres.2013.01.006. Epub 2013 Jan 23. PubMed PMID: 23351664. 9 64: O'Neil WM, Welner SA, Lip GY. Do open label blinded outcome studies of novel anticoagulants versus warfarin have equivalent validity to those carried out under double-blind conditions? Thromb Haemost. 2013 Mar 5;109(3):497-503. doi: 10.1160/TH12-10-0715. Epub 2013 Jan 24. PubMed PMID: 23348922. 65: Apostolakis S, Lane DA, Guo Y, Buller H, Lip GY. Reply. J Am Coll Cardiol. 2013 Jan 29;61(4):482-3. doi: 10.1016/j.jacc.2012.10.033. PubMed PMID: 23347785. 66: Roldán V, Marín F, Fernández H, Manzano-Fernández S, Gallego P, Valdés M, Vicente V, Lip GY. Renal impairment in a "real-life" cohort of anticoagulated patients with atrial fibrillation (implications for thromboembolism and bleeding). Am J Cardiol. 2013 Apr 15;111(8):1159-64. doi: 10.1016/j.amjcard.2012.12.045. Epub 2013 Jan 18. PubMed PMID: 23337836. 67: Lip GY, Lin HJ, Hsu HC, Su TC, Chen MF, Lee YT, Chien KL. Comparative assessment of the HAS-BLED score with other published bleeding risk scoring schemes, for intracranial haemorrhage risk in a non-atrial fibrillation population: The Chin-Shan Community Cohort Study. Int J Cardiol. 2013 Jan 18. doi:pii: S0167-5273(12)01705-6. 10.1016/j.ijcard.2012.12.076. [Epub ahead of print] PubMed PMID: 23336959. 68: Proclemer A, Dagres N, Marinskis G, Pison L, Lip GY, Blomstrom-Lundqvist C; Scientific Initiative Committee, European Heart Rhythm Association. Current practice in Europe: how do we manage patients with ventricular tachycardia? European Heart Rhythm Association survey. Europace. 2013 Feb;15(2):167-9. doi: 10.1093/europace/eus436. PubMed PMID: 23334717. 69: Blann AD, Lip GY. Atrial fibrillation and thrombosis: the missing molecular links. J Am Coll Cardiol. 2013 Feb 26;61(8):861-2. doi: 10.1016/j.jacc.2012.11.047. Epub 2013 Jan 16. PubMed PMID: 23333144. 70: Shantsila E, Shantsila A, Blann AD, Lip GY. Left ventricular fibrosis in atrial fibrillation. Am J Cardiol. 2013 Apr 1;111(7):996-1001. doi: 10.1016/j.amjcard.2012.12.005. Epub 2013 Jan 17. PubMed PMID: 23332595. 71: Adlan AM, Lip GY. Benefit-risk assessment of dronedarone in the treatment of atrial fibrillation. Drug Saf. 2013 Feb;36(2):93-110. doi: 10 10.1007/s40264-012-0012-8. PubMed PMID: 23329540. 72: Potpara TS, Polovina MM, Licina MM, Marinkovic JM, Lip GY. Predictors and prognostic implications of incident heart failure following the first diagnosis of atrial fibrillation in patients with structurally normal hearts: the Belgrade Atrial Fibrillation Study. Eur J Heart Fail. 2013 Apr;15(4):415-24. doi: 10.1093/eurjhf/hft004. Epub 2013 Jan 9. PubMed PMID: 23302606. 73: Kasmeridis C, Apostolakis S, Lip GY. Aspirin and aspirin resistance in coronary artery disease. Curr Opin Pharmacol. 2013 Jan 5. doi:pii: S1471-4892(12)00241-X. 10.1016/j.coph.2012.12.004. [Epub ahead of print] PubMed PMID: 23294895. 74: Riva N, Lip GY. Which is the Optimal Antihypertensive Combination in Different Diseases, a Renin- Angiotensin-aldosterone System Inhibitor with a Diuretic or with a Calcium Channel Blocker? Curr Pharm Des. 2013;19(21):3753-65. PubMed PMID: 23286431. 75: Hernández-Romero D, Jover E, Marín F, Vilchez JA, Manzano-Fernandez S, Romera M, Vicente V, Valdés M, Lip GY, Roldán V. The prognostic role of the adiponectin levels in atrial fibrillation. Eur J Clin Invest. 2013 Feb;43(2):168-73. doi: 10.1111/eci.12028. Epub 2012 Dec 20. PubMed PMID: 23278336. 76: Lip GY, Larsen TB, Skjøth F, Rasmussen LH. Reply. J Am Coll Cardiol. 2013 Feb 5;61(5):596. doi: 10.1016/j.jacc.2012.10.034. Epub 2012 Dec 26. PubMed PMID: 23273397. 77: Holt TA, Hunter TD, Gunnarsson C, Khan N, Cload P, Lip GY. Risk of stroke and oral anticoagulant use in atrial fibrillation: a cross-sectional survey. Br J Gen Pract. 2012 Oct;62(603):e710-7. doi: 10.3399/bjgp12X656856. PubMed PMID: 23265231; PubMed Central PMCID: PMC3459779. 78: Durrant J, Lip GY, Lane DA. Stroke risk stratification scores in atrial fibrillation: current recommendations for clinical practice and future perspectives. Expert Rev Cardiovasc Ther. 2013 Jan;11(1):77-90. doi: 10.1586/erc.12.161. Review. PubMed PMID: 23259448. 79: Lip GY. Stroke and bleeding risk assessment in atrial fibrillation: when, 11 how, and why? Eur Heart J. 2013 Apr;34(14):1041-9. doi: 10.1093/eurheartj/ehs435. Epub 2012 Dec 20. PubMed PMID: 23257951. 80: Ahmad Y, Lip GY, Apostolakis S. New oral anticoagulants for stroke prevention in atrial fibrillation: impact of gender, heart failure, diabetes mellitus and paroxysmal atrial fibrillation. Expert Rev Cardiovasc Ther. 2012 Dec;10(12):1471-80. doi: 10.1586/erc.12.148. Review. PubMed PMID: 23253272. 81: Apostolakis S, Lane DA, Guo Y, Buller H, Lip GY. Performance of the HEMORR 2 HAGES, ATRIA, and HAS-BLED bleeding risk-prediction scores in nonwarfarin anticoagulated atrial fibrillation patients. J Am Coll Cardiol. 2013 Jan 22;61(3):386-7. doi: 10.1016/j.jacc.2012.10.010. Epub 2012 Dec 12. PubMed PMID: 23246385. 82: Lee S, Monz BU, Clemens A, Brueckmann M, Lip GY. Representativeness of the dabigatran, apixaban and rivaroxaban clinical trial populations to real-world atrial fibrillation patients in the United Kingdom: a cross-sectional analysis using the General Practice Research Database. BMJ Open. 2012 Dec 14;2(6). doi:pii: e001768. 10.1136/bmjopen-2012-001768. Print 2012. PubMed PMID: 23242482; PubMed Central PMCID: PMC3533028. 83: Wrigley BJ, Shantsila E, Tapp LD, Lip GY. CD14++CD16+ monocytes in patients with acute ischaemic heart failure. Eur J Clin Invest. 2013 Feb;43(2):121-30. doi: 10.1111/eci.12023. Epub 2012 Dec 14. PubMed PMID: 23240665. 84: Lip GY, Dagres N, Proclemer A, Svendsen JH, Pison L, Blomstrom-Lundqvist C; Scientific Initiative Committee, European Heart Rhythm Association. Left atrial appendage occlusion for stroke prevention in atrial fibrillation in Europe: results of the European Heart Rhythm Association survey. Europace. 2013 Jan;15(1):141-3. doi: 10.1093/europace/eus413. PubMed PMID: 23233491. 85: Kornej J, Lip GY, Bollmann A. Reduction of stroke and mortality in patients with atrial fibrillation by catheter ablation? Finally, tackling the hard endpoints. Europace. 2013 May;15(5):620-2. doi: 10.1093/europace/eus389. Epub 2012 Dec 11. PubMed PMID: 23233210. 86: Pisters R, Lip GY. Safety and efficacy of new anticoagulants in patients with heart failure. Curr Heart Fail Rep. 2013 Mar;10(1):18-25. doi: 10.1007/s11897-012-0125-5. PubMed PMID: 23229176. 12 87: López-Cuenca A, Manzano-Fernández S, Lip GY, Casas T, Sánchez-Martínez M, Mateo-Martínez A, Pérez-Berbel P, Martínez J, Hernández-Romero D, Romero Aniorte AI, Valdés M, Marín F. Interleukin-6 and High-sensitivity C-reactive Protein for the Prediction of Outcomes in Non-ST-segment Elevation Acute Coronary Syndromes. Rev Esp Cardiol. 2013 Mar;66(3):185-192. doi: 10.1016/j.recesp.2012.07.027. Epub 2012 Dec 8. English, Spanish. PubMed PMID: 23228342. 88: Shantsila E, Tapp LD, Wrigley BJ, Montoro-García S, Lip GY. CXCR4 positive and angiogenic monocytes in myocardial infarction. Thromb Haemost. 2013 Feb;109(2):255-62. doi: 10.1160/TH12-06-0395. Epub 2012 Dec 6. PubMed PMID: 23223950. 89: Kuzniatsova N, Shantsila E, Lip GY, Blann AD. The membrane expression of P-selectin, but not monocyte-platelet aggregates, is influenced by variability in response to aspirin in patients with coronary artery disease. Platelets. 2012 Dec 5. [Epub ahead of print] PubMed PMID: 23216649. 90: Jover E, Marín F, Roldán V, Montoro-García S, Valdés M, Lip GY. Atherosclerosis and thromboembolic risk in atrial fibrillation: focus on peripheral vascular disease. Ann Med. 2013 May;45(3):274-90. doi: 10.3109/07853890.2012.732702. Epub 2012 Dec 8. PubMed PMID: 23216106. 91: Guo Y, Lip GY, Apostolakis S. The challenge of antiplatelet therapy in patients with atrial fibrillation and heart failure. J Cardiovasc Transl Res. 2013 Jun;6(3):388-97. doi: 10.1007/s12265-012-9427-y. Epub 2012 Dec 4. PubMed PMID: 23208014. 92: Harenberg J, Lip GY. Differences between indirect comparison studies of the oral anticoagulants for stroke prevention in atrial fibrillation: where do we go next? QJM. 2013 Jan;106(1):95-6. doi: 10.1093/qjmed/hcs224. Epub 2012 Dec 1. PubMed PMID: 23204530. 93: Marín F, Lip GY. Oral anticoagulation for heart failure in sinus rhythm: from evidence to clinical recommendations, or not? Eur J Heart Fail. 2013 Jan;15(1):3-4. doi: 10.1093/eurjhf/hfs198. Epub 2012 Nov 29. PubMed PMID: 23204212. 13 94: Blann AD, Kuzniatsova N, Lip GY. Vascular and platelet responses to aspirin in patients with coronary artery disease. Eur J Clin Invest. 2013 Jan;43(1):91-9. doi: 10.1111/eci.12021. Epub 2012 Dec 2. PubMed PMID: 23198725. 95: Guo Y, Lip GY, Apostolakis S. Inflammation in atrial fibrillation. J Am Coll Cardiol. 2012 Dec 4;60(22):2263-70. doi: 10.1016/j.jacc.2012.04.063. Review. PubMed PMID: 23194937. 96: Adlan AM, Lip GY, Fadel PJ, Fisher JP. Sympathetic nerve activity during non-sustained ventricular tachycardia in chronic heart failure. Int J Cardiol. 2013 May 10;165(2):e15-7. doi: 10.1016/j.ijcard.2012.10.088. Epub 2012 Nov 22. PubMed PMID: 23181998. 97: Pisters R, Nieuwlaat R, Lane DA, Crijns HJ, Lip GY. Potential net clinical benefit of population-wide implementation of apixaban and dabigatran among European patients with atrial fibrillation. A modelling analysis from the Euro Heart Survey. Thromb Haemost. 2013 Feb;109(2):328-36. doi: 10.1160/TH12-08-0539. Epub 2012 Nov 22. PubMed PMID: 23179181. 98: Guo Y, Apostolakis S, Blann AD, Wang H, Zhao X, Zhang Y, Zhang D, Ma J, Wang Y, Lip GY. Validation of contemporary stroke and bleeding risk stratification scores in non-anticoagulated Chinese patients with atrial fibrillation. Int J Cardiol. 2012 Nov 17. doi:pii: S0167-5273(12)01427-1. 10.1016/j.ijcard.2012.10.052. [Epub ahead of print] PubMed PMID: 23167998. 99: Wrigley BJ, Shantsila E, Tapp LD, Lip GY. Increased formation of monocyte-platelet aggregates in ischemic heart failure. Circ Heart Fail. 2013 Jan;6(1):127-35. doi: 10.1161/CIRCHEARTFAILURE.112.968073. Epub 2012 Nov 14. PubMed PMID: 23152489. 100: Kalitzeos AA, Lip GY, Heitmar R. Retinal vessel tortuosity measures and their applications. Exp Eye Res. 2013 Jan;106:40-6. doi: 10.1016/j.exer.2012.10.015. Epub 2012 Nov 9. PubMed PMID: 23146682. 101: Patel JV, Chackathayil J, Gammon B, Tracey I, Lovick A, Gill PS, Banerjee A, Scarff CA, Scrivens JH, Lip GY, Hughes EA. Is the higher risk of cardiovascular disease amongst South Asian populations linked to abnormalities of haemoglobin? A preliminary case control study. Atherosclerosis. 2013 Jan;226(1):198-200. doi: 10.1016/j.atherosclerosis.2012.09.017. Epub 2012 Oct 25. PubMed PMID: 23141472. 14 102: Patel JV, Chackathayil J, Hughes EA, Webster C, Lip GY, Gill PS. Vitamin D deficiency amongst minority ethnic groups in the UK: a cross sectional study. Int J Cardiol. 2012 Jun 19. [Epub ahead of print] PubMed PMID: 23140614. 103: Marinskis G, Bongiorni MG, Dagres N, Dobreanu D, Lewalter T, Blomström-Lundqvist C; Scientific Initiative Committee, European Heart Rhythm Association. Performing magnetic resonance imaging in patients with implantable pacemakers and defibrillators: results of a European Heart Rhythm Association survey. Europace. 2012 Dec;14(12):1807-9. doi: 10.1093/europace/eus379. Epub 2012 Nov 6. PubMed PMID: 23134623. 104: Rasmussen LH, Larsen TB, Graungaard T, Skjøth F, Lip GY. Primary and secondary prevention with new oral anticoagulant drugs for stroke prevention in atrial fibrillation: indirect comparison analysis. BMJ. 2012 Nov 5;345:e7097. doi: 10.1136/bmj.e7097. PubMed PMID: 23129490; PubMed Central PMCID: PMC3489505. 105: Schwartz GG, Olsson AG, Abt M, Ballantyne CM, Barter PJ, Brumm J, Chaitman BR, Holme IM, Kallend D, Leiter LA, Leitersdorf E, McMurray JJ, Mundl H, Nicholls SJ, Shah PK, Tardif JC, Wright RS; dal-OUTCOMES Investigators. Effects of dalcetrapib in patients with a recent acute coronary syndrome. N Engl J Med. 2012 Nov 29;367(22):2089-99. doi: 10.1056/NEJMoa1206797. Epub 2012 Nov 5. PubMed PMID: 23126252. 106: Tapp LD, Shantsila E, Wrigley BJ, Montoro-Garcia S, Lip GY. TLR4 expression on monocyte subsets in myocardial infarction. J Intern Med. 2013 Mar;273(3):294-305. doi: 10.1111/joim.12011. Epub 2012 Dec 28. PubMed PMID: 23121518. 107: Gallego P, Marin F, Lip GY. Prior aspirin therapy and cardiovascular implantable electronic device infections. Europace. 2013 Feb;15(2):163-4. doi: 10.1093/europace/eus346. Epub 2012 Nov 1. PubMed PMID: 23118008. 108: Orenes-Piñero E, Montoro-García S, Banerjee A, Valdés M, Lip GY, Marín F. Pre and post-operative treatments for prevention of atrial fibrillation after cardiac surgery. Mini Rev Med Chem. 2012 Nov;12(13):1419-31. PubMed PMID: 23106292. 15 109: Bongiorni MG, Marinskis G, Lip GY, Svendsen JH, Dobreanu D, Blomström-Lundqvist C; Scientific Initiative Committee, European Heart Rhythm Association. How European centres diagnose, treat, and prevent CIED infections: results of an European Heart Rhythm Association survey. Europace. 2012 Nov;14(11):1666-9. doi: 10.1093/europace/eus350. PubMed PMID: 23104858. 110: Guo Y, Pisters R, Apostolakis S, Blann AD, Wang H, Zhao X, Zhang Y, Zhang D, Ma J, Wang Y, Lip GY. Stroke risk and suboptimal thromboprophylaxis in Chinese patients with atrial fibrillation: Would the novel oral anticoagulants have an impact? Int J Cardiol. 2012 Oct 23. doi:pii: S0167-5273(12)01308-3. 10.1016/j.ijcard.2012.09.187. [Epub ahead of print] PubMed PMID: 23103146. 111: Ruiz-Nodar JM, Marín F, Lip GY. Antithrombotic management and type of stent in atrial fibrillation patients undergoing percutaneous coronary intervention. Rev Esp Cardiol (Engl Ed). 2013 Jan;66(1):12-6. doi: 10.1016/j.recesp.2012.07.018. Epub 2012 Oct 23. English, Spanish. PubMed PMID: 23098580. 112: Lip GY, Piotrponikowski P, Andreotti F, Anker SD, Filippatos G, Homma S, Morais J, Pullicino P, Rasmussen LH, Marín F, Lane DA; Heart Failure Association (EHFA) of the European Society of Cardiology (ESC) and the ESC Working Group on Thrombosis. Thromboembolism and antithrombotic therapy for heart failure in sinus rhythm: an executive summary of a joint consensus document from the ESC Heart Failure Association and the ESC Working Group on Thrombosis. Thromb Haemost. 2012 Dec;108(6):1009-22. doi: 10.1160/TH12-08-0578. Epub 2012 Oct 23. PubMed PMID: 23093044. 113: Lip GY, Lin HJ, Chien KL, Hsu HC, Su TC, Chen MF, Lee YT. Comparative assessment of published atrial fibrillation stroke risk stratification schemes for predicting stroke, in a non-atrial fibrillation population: The Chin-Shan Community Cohort Study. Int J Cardiol. 2012 Oct 13. doi:pii: S0167-5273(12)01269-7. 10.1016/j.ijcard.2012.09.148. [Epub ahead of print] PubMed PMID: 23073283. 114: Dentali F, Riva N, Crowther M, Turpie AG, Lip GY, Ageno W. Efficacy and safety of the novel oral anticoagulants in atrial fibrillation: a systematic review and meta-analysis of the literature. Circulation. 2012 Nov 13;126(20):2381-91. doi: 10.1161/CIRCULATIONAHA.112.115410. Epub 2012 Oct 15. Review. PubMed PMID: 23071159. 16 115: Orenes-Piñero E, Montoro-García S, Patel JV, Valdés M, Marín F, Lip GY. Role of microRNAs in cardiac remodelling: New insights and future perspectives. Int J Cardiol. 2012 Oct 9. doi:pii: S0167-5273(12)01241-7. 10.1016/j.ijcard.2012.09.120. [Epub ahead of print] PubMed PMID: 23063140. 116: Gallego P, Roldán V, Marín F, Jover E, Manzano-Fernández S, Valdés M, Vicente V, Lip GY. Ankle brachial index as an independent predictor of mortality in anticoagulated atrial fibrillation. Eur J Clin Invest. 2012 Dec;42(12):1302-8. doi: 10.1111/eci.12004. Epub 2012 Oct 11. PubMed PMID: 23057651. 117: Vaduganathan M, Greene SJ, Butler J, Sabbah HN, Shantsila E, Lip GY, Gheorghiade M. The immunological axis in heart failure: importance of the leukocyte differential. Heart Fail Rev. 2012 Oct 7. [Epub ahead of print] PubMed PMID: 23054221. 118: Flaker GC, Eikelboom JW, Shestakovska O, Connolly SJ, Kaatz S, Budaj A, Husted S, Yusuf S, Lip GY, Hart RG. Bleeding during treatment with aspirin versus apixaban in patients with atrial fibrillation unsuitable for warfarin: the apixaban versus acetylsalicylic acid to prevent stroke in atrial fibrillation patients who have failed or are unsuitable for vitamin K antagonist treatment (AVERROES) trial. Stroke. 2012 Dec;43(12):3291-7. doi: 10.1161/STROKEAHA.112.664144. Epub 2012 Oct 2. PubMed PMID: 23033347. 119: Crijns HJ, Bash LD, Chazelle F, Le Heuzey JY, Lewalter T, Lip GY, Maggioni AP, Martín A, Ponikowski P, Rosenqvist M, Sanders P, Scanavacca M, Bernhardt AA, Unniachan S, Phatak HM, Gitt AK. RHYTHM-AF: design of an international registry on cardioversion of atrial fibrillation and characteristics of participating centers. BMC Cardiovasc Disord. 2012 Oct 2;12:85. doi: 10.1186/1471-2261-12-85. PubMed PMID: 23031215; PubMed Central PMCID: PMC3507765. 120: Coppens M, Eikelboom JW, Hart RG, Yusuf S, Lip GY, Dorian P, Shestakovska O, Connolly SJ. The CHA2DS2-VASc score identifies those patients with atrial fibrillation and a CHADS2 score of 1 who are unlikely to benefit from oral anticoagulant therapy. Eur Heart J. 2013 Jan;34(3):170-6. doi: 10.1093/eurheartj/ehs314. Epub 2012 Sep 27. PubMed PMID: 23018151. 121: Guo Y, Lip GY, Apostolakis S. Bridging Therapy: A Challenging Area in the Management of Patients with Atrial Fibrillation. Am J Cardiovasc Drugs. 2012 Sep 28. doi: 10.2165/11634490-000000000-00000. [Epub ahead of print] PubMed PMID: 23017110. 17 122: Lewalter T, Dobreanu D, Proclemer A, Marinskis G, Pison L, Blomström-Lundqvist C; Scientific Initiative Committee-European Heart Rhythm Association. Atrial fibrillation ablation techniques. Europace. 2012 Oct;14(10):1515-7. PubMed PMID: 23015690. 123: Gallego P, Apostolakis S, Lip GY. Bridging evidence-based practice and practice-based evidence in periprocedural anticoagulation. Circulation. 2012 Sep 25;126(13):1573-6. PubMed PMID: 23008469. 124: Pisters R, Lane DA, Marin F, Camm AJ, Lip GY. Stroke and thromboembolism in atrial fibrillation. Circ J. 2012;76(10):2289-304. Epub 2012 Sep 19. Review. PubMed PMID: 23001018. 125: Sullivan RM, Zhang J, Zamba G, Lip GY, Olshansky B. Relation of gender-specific risk of ischemic stroke in patients with atrial fibrillation to differences in warfarin anticoagulation control (from AFFIRM). Am J Cardiol. 2012 Dec 15;110(12):1799-802. doi: 10.1016/j.amjcard.2012.08.014. Epub 2012 Sep 18. PubMed PMID: 22995971. 126: Caballero L, Ruiz-Nodar JM, Marín F, Roldán V, Hurtado JA, Valencia J, Manzano-Fernandez S, Sogorb F, Valdes M, Lip GY. Oral anticoagulation improves the prognosis of octogenarian patients with atrial fibrillation undergoing percutaneous coronary intervention and stenting. Age Ageing. 2013 Jan;42(1):70-5. doi: 10.1093/ageing/afs121. Epub 2012 Sep 14. PubMed PMID: 22983982. 127: Camm AJ, Al-Khatib SM, Calkins H, Halperin JL, Kirchhof P, Lip GY, Nattel S, Ruskin J, Banerjee A, Blendea D, Guasch E, Needleman M, Savelieva I, Viles-Gonzalez J, Williams ES. A proposal for new clinical concepts in the management of atrial fibrillation. Am Heart J. 2012 Sep;164(3):292-302.e1. doi: 10.1016/j.ahj.2012.05.017. Epub 2012 Aug 3. Review. PubMed PMID: 22980294. 128: Roldán V, Marín F, Gallego P, Vicente V, Lip GY. Cardiac troponins and the risk of stroke in atrial fibrillation. Cause or consequence? J Thromb Haemost. 2012 Sep 10. doi: 10.1111/j.1538-7836.2012.04918.x. [Epub ahead of print] PubMed PMID: 22963074. 129: Jaipersad AS, Shantsila A, Silverman S, Lip GY, Shantsila E. Evaluation of 18 Carotid Plaque Neovascularization Using Contrast Ultrasound. Angiology. 2012 Sep 14. [Epub ahead of print] PubMed PMID: 22923703. 130: Christensen AL, Rasmussen LH, Baker MG, Lip GY, Dethlefsen C, Larsen TB. Seasonality, incidence and prognosis in atrial fibrillation and stroke in Denmark and New Zealand. BMJ Open. 2012 Aug 24;2(4). doi:pii: e001210. 10.1136/bmjopen-2012-001210. Print 2012. PubMed PMID: 22923628; PubMed Central PMCID: PMC3432837. 131: Lip GY, Banerjee A, Lagrenade I, Lane DA, Taillandier S, Fauchier L. Assessing the risk of bleeding in patients with atrial fibrillation: the Loire Valley Atrial Fibrillation project. Circ Arrhythm Electrophysiol. 2012 Oct;5(5):941-8. doi: 10.1161/CIRCEP.112.972869. Epub 2012 Aug 24. PubMed PMID: 22923275. 132: Camm AJ, Lip GY, De Caterina R, Savelieva I, Atar D, Hohnloser SH, Hindricks G, Kirchhof P; ESC Committee for Practice Guidelines-CPG; Document Reviewers. 2012 focused update of the ESC Guidelines for the management of atrial fibrillation: an update of the 2010 ESC Guidelines for the management of atrial fibrillation--developed with the special contribution of the European Heart Rhythm Association. Europace. 2012 Oct;14(10):1385-413. Epub 2012 Aug 24. PubMed PMID: 22923145. 133: Vahanian A, Alfieri O, Andreotti F, Antunes MJ, Barón-Esquivias G, Baumgartner H, Borger MA, Carrel TP, De Bonis M, Evangelista A, Falk V, Lung B, Lancellotti P, Pierard L, Price S, Schäfers HJ, Schuler G, Stepinska J, Swedberg K, Takkenberg J, Von Oppell UO, Windecker S, Zamorano JL, Zembala M; ESC Committee for Practice Guidelines (CPG); Joint Task Force on the Management of Valvular Heart Disease of the European Society of Cardiology (ESC); European Association for Cardio-Thoracic Surgery (EACTS). Guidelines on the management of valvular heart disease (version 2012): the Joint Task Force on the Management of Valvular Heart Disease of the European Society of Cardiology (ESC) and the European Association for Cardio-Thoracic Surgery (EACTS). Eur J Cardiothorac Surg. 2012 Oct;42(4):S1-44. doi: 10.1093/ejcts/ezs455. Epub 2012 Aug 25. PubMed PMID: 22922698. 134: Joint Task Force on the Management of Valvular Heart Disease of the European Society of Cardiology (ESC); European Association for Cardio-Thoracic Surgery (EACTS), Vahanian A, Alfieri O, Andreotti F, Antunes MJ, Barón-Esquivias G, Baumgartner H, Borger MA, Carrel TP, De Bonis M, Evangelista A, Falk V, Iung B, Lancellotti P, Pierard L, Price S, Schäfers HJ, Schuler G, Stepinska J, Swedberg 19 K, Takkenberg J, Von Oppell UO, Windecker S, Zamorano JL, Zembala M. Guidelines on the management of valvular heart disease (version 2012). Eur Heart J. 2012 Oct;33(19):2451-96. doi: 10.1093/eurheartj/ehs109. Epub 2012 Aug 24. PubMed PMID: 22922415. 135: Camm AJ, Lip GY, De Caterina R, Savelieva I, Atar D, Hohnloser SH, Hindricks G, Kirchhof P; ESC Committee for Practice Guidelines (CPG), Bax JJ, Baumgartner H, Ceconi C, Dean V, Deaton C, Fagard R, Funck-Brentano C, Hasdai D, Hoes A, Kirchhof P, Knuuti J, Kolh P, McDonagh T, Moulin C, Popescu BA, Reiner Z, Sechtem U, Sirnes PA, Tendera M, Torbicki A, Vahanian A, Windecker S; Document Reviewers, Vardas P, Al-Attar N, Alfieri O, Angelini A, Blömstrom-Lundqvist C, Colonna P, De Sutter J, Ernst S, Goette A, Gorenek B, Hatala R, Heidbüchel H, Heldal M, Kristensen SD, Kolh P, Le Heuzey JY, Mavrakis H, Mont L, Filardi PP, Ponikowski P, Prendergast B, Rutten FH, Schotten U, Van Gelder IC, Verheugt FW. 2012 focused update of the ESC Guidelines for the management of atrial fibrillation: an update of the 2010 ESC Guidelines for the management of atrial fibrillation. Developed with the special contribution of the European Heart Rhythm Association. Eur Heart J. 2012 Nov;33(21):2719-47. doi: 10.1093/eurheartj/ehs253. Epub 2012 Aug 24. Erratum in: Eur Heart J. 2013 Mar;34(10):790. PubMed PMID: 22922413. 136: Ahmad Y, Lip GY. Stroke prevention in atrial fibrillation: concepts and controversies. Curr Cardiol Rev. 2012 Nov;8(4):290-301. Review. PubMed PMID: 22920480; PubMed Central PMCID: PMC3492813. 137: Apostolakis S, Marín F, Lip GY. Antiplatelet therapy in stroke prevention. Adv Cardiol. 2012;47:141-54. doi: 10.1159/000338050. Epub 2012 Aug 9. Review. PubMed PMID: 22906909. 138: Lip GY, Ramsay SG. Insights from the RCPE UK Consensus Conference on approaching the comprehensive management of atrial fibrillation. Expert Rev Cardiovasc Ther. 2012 Jun;10(6):697-700. doi: 10.1586/erc.12.48. PubMed PMID: 22894625. 139: Olesen JB, Lip GY, Kamper AL, Hommel K, Køber L, Lane DA, Lindhardsen J, Gislason GH, Torp-Pedersen C. Stroke and bleeding in atrial fibrillation with chronic kidney disease. N Engl J Med. 2012 Aug 16;367(7):625-35. doi: 10.1056/NEJMoa1105594. Erratum in: N Engl J Med. 2012 Dec 6;367(23):2262. PubMed PMID: 22894575. 140: Lane DA, Lip GY. Use of the CHA(2)DS(2)-VASc and HAS-BLED scores to aid 20 decision making for thromboprophylaxis in nonvalvular atrial fibrillation. Circulation. 2012 Aug 14;126(7):860-5. doi: 10.1161/CIRCULATIONAHA.111.060061. PubMed PMID: 22891166. 141: Albertsen IE, Larsen TB, Rasmussen LH, Overvad TF, Lip GY. Prevention of venous thromboembolism with new oral anticoagulants versus standard pharmacological treatment in acute medically ill patients: a systematic review and meta-analysis. Drugs. 2012 Sep 10;72(13):1755-64. doi: 10.2165/11635630-000000000-00000. Review. PubMed PMID: 22876779. 142: Apostolakis S, Lane DA, Guo Y, Buller H, Lip GY. Performance of the HEMORR(2)HAGES, ATRIA, and HAS-BLED bleeding risk-prediction scores in patients with atrial fibrillation undergoing anticoagulation: the AMADEUS (evaluating the use of SR34006 compared to warfarin or acenocoumarol in patients with atrial fibrillation) study. J Am Coll Cardiol. 2012 Aug 28;60(9):861-7. doi: 10.1016/j.jacc.2012.06.019. Epub 2012 Aug 1. PubMed PMID: 22858389. 143: Proclemer A, Dobreanu D, Pison L, Lip GY, Svendsen JH, Lundqvist CB; Scientific Initiative Committee-European Heart Rhythm Association. Current practice in out-of-hospital cardiac arrest management: a European heart rhythm association EP network survey. Europace. 2012 Aug;14(8):1195-8. doi: 10.1093/europace/eus232. PubMed PMID: 22832576. 144: McMurray JJ, Adamopoulos S, Anker SD, Auricchio A, Böhm M, Dickstein K, Falk V, Filippatos G, Fonseca C, Gomez-Sanchez MA, Jaarsma T, Køber L, Lip GY, Maggioni AP, Parkhomenko A, Pieske BM, Popescu BA, Rønnevik PK, Rutten FH, Schwitter J, Seferovic P, Stepinska J, Trindade PT, Voors AA, Zannad F, Zeiher A; Task Force for the Diagnosis and Treatment of Acute and Chronic Heart Failure 2012 of the European Society of Cardiology, Bax JJ, Baumgartner H, Ceconi C, Dean V, Deaton C, Fagard R, Funck-Brentano C, Hasdai D, Hoes A, Kirchhof P, Knuuti J, Kolh P, McDonagh T, Moulin C, Popescu BA, Reiner Z, Sechtem U, Sirnes PA, Tendera M, Torbicki A, Vahanian A, Windecker S, McDonagh T, Sechtem U, Bonet LA, Avraamides P, Ben Lamin HA, Brignole M, Coca A, Cowburn P, Dargie H, Elliott P, Flachskampf FA, Guida GF, Hardman S, Iung B, Merkely B, Mueller C, Nanas JN, Nielsen OW, Orn S, Parissis JT, Ponikowski P; ESC Committee for Practice Guidelines. ESC guidelines for the diagnosis and treatment of acute and chronic heart failure 2012: The Task Force for the Diagnosis and Treatment of Acute and Chronic Heart Failure 2012 of the European Society of Cardiology. Developed in collaboration with the Heart Failure Association (HFA) of the ESC. Eur J Heart Fail. 2012 Aug;14(8):803-69. doi: 10.1093/eurjhf/hfs105. Erratum in: Eur J Heart Fail. 2013 Mar;15(3):361-2. PubMed PMID: 22828712. 21 145: Pisters R, Lip GY. Periprocedural antithrombotic management of patients undergoing ablation for atrial fibrillation: what we currently do...and what should we do? Can J Cardiol. 2013 Feb;29(2):139-41. doi: 10.1016/j.cjca.2012.05.016. Epub 2012 Jul 20. PubMed PMID: 22819445. 146: Blann AD, Kuzniatsova N, Velu S, Lip GY. Renal function and aspirin resistance in patients with coronary artery disease. Thromb Res. 2012 Sep;130(3):e103-6. doi: 10.1016/j.thromres.2012.06.026. Epub 2012 Jul 17. PubMed PMID: 22809843. 147: Mikkelsen AP, Lindhardsen J, Lip GY, Gislason GH, Torp-Pedersen C, Olesen JB. Female sex as a risk factor for stroke in atrial fibrillation: a nationwide cohort study. J Thromb Haemost. 2012 Sep;10(9):1745-51. doi: 10.1111/j.1538-7836.2012.04853.x. PubMed PMID: 22805071. 148: Harenberg J, Marx S, Diener HC, Lip GY, Marder VJ, Wehling M, Weiss C. Comparison of efficacy and safety of dabigatran, rivaroxaban and apixaban in patients with atrial fibrillation using network meta-analysis. Int Angiol. 2012 Aug;31(4):330-9. Review. PubMed PMID: 22801398. 149: Banerjee A, Taillandier S, Olesen JB, Lane DA, Lallemand B, Lip GY, Fauchier L. Pattern of atrial fibrillation and risk of outcomes: The Loire Valley Atrial Fibrillation Project. Int J Cardiol. 2012 Jul 13. [Epub ahead of print] PubMed PMID: 22795403. 150: Ruiz-Nodar JM, Marín F, Roldán V, Valencia J, Manzano-Fernández S, Caballero L, Hurtado JA, Sogorb F, Valdés M, Lip GY. Should we recommend oral anticoagulation therapy in patients with atrial fibrillation undergoing coronary artery stenting with a high HAS-BLED bleeding risk score? Circ Cardiovasc Interv. 2012 Aug 1;5(4):459-66. doi: 10.1161/CIRCINTERVENTIONS.112.968792. Epub 2012 Jul 10. PubMed PMID: 22787018. 151: Roldán V, Marín F, Lip GY. Edoxaban in Japanese patients with nonvalvular atrial fibrillation: not the same dose for everybody. Circ J. 2012;76(8):1826-7. Epub 2012 Jul 29. PubMed PMID: 22785373. 152: Lip GY, Rasmussen LH, Skjøth F, Overvad K, Larsen TB. Stroke and mortality in patients with incident heart failure: the Diet, Cancer and Health (DCH) cohort 22 study. BMJ Open. 2012 Jul 7;2(4). doi:pii: e000975. 10.1136/bmjopen-2012-000975. Print 2012. PubMed PMID: 22773537. 153: Toor IS, Jaumdally R, Lip GY, Millane T, Varma C. Eosinophil count predicts mortality following percutaneous coronary intervention. Thromb Res. 2012 Oct;130(4):607-11. doi: 10.1016/j.thromres.2012.05.033. Epub 2012 Jul 6. PubMed PMID: 22771073. 154: Ahrens I, Peter K, Lip GY, Bode C. Development and clinical applications of novel oral anticoagulants. Part II. Drugs under clinical investigation. Discov Med. 2012 Jun;13(73):445-50. Review. PubMed PMID: 22742650. 155: Ahrens I, Peter K, Lip GY, Bode C. Development and clinical applications of novel oral anticoagulants. Part I. Clinically approved drugs. Discov Med. 2012 Jun;13(73):433-43. Review. PubMed PMID: 22742649. 156: Montoro-García S, Shantsila E, Orenes-Piñero E, Lozano ML, Lip GY. An innovative flow cytometric approach for small-size platelet microparticles: influence of calcium. Thromb Haemost. 2012 Aug;108(2):373-83. doi: 10.1160/TH12-02-0120. Epub 2012 Jun 28. PubMed PMID: 22740162. 157: Schilling RJ, Camm J, Lip G, Grace A, Fay M, Fitzpatrick A, Wolff A, Lobban T. Seek referral to a heart rhythm specialist for atrial fibrillation. BMJ. 2012 Jun 25;344:e4318. doi: 10.1136/bmj.e4318. PubMed PMID: 22734100. 158: Potpara TS, Lip GY, Apostolakis S. New anticoagulant treatments to protect against stroke in atrial fibrillation. Heart. 2012 Sep;98(18):1341-7. doi: 10.1136/heartjnl-2012-301841. Epub 2012 Jun 22. Review. PubMed PMID: 22730480. 159: Roldán V, Marín F, Fernández H, Manzano-Fernandez S, Gallego P, Valdés M, Vicente V, Lip GY. Predictive value of the HAS-BLED and ATRIA bleeding scores for the risk of serious bleeding in a "real-world" population with atrial fibrillation receiving anticoagulant therapy. Chest. 2013 Jan;143(1):179-84. PubMed PMID: 22722228. 160: Hernández-Romero D, Marín F, Roldán V, Lip GY. Subclinical atherosclerotic endothelial damage as predictor for bleeding in anticoagulated atrial fibrillation patients. J Intern Med. 2012 Oct;272(4):409. doi: 23 10.1111/j.1365-2796.2012.02565.x. Epub 2012 Jul 27. PubMed PMID: 22702474. 161: Ahmad Y, Lip GY. Dabigatran etexilate for the prevention of stroke and systemic embolism in atrial fibrillation: NICE guidance. Heart. 2012 Oct;98(19):1404-6. doi: 10.1136/heartjnl-2012-302101. Epub 2012 Jun 14. PubMed PMID: 22698856. 162: Lip GY, Wrigley BJ, Pisters R. Anticoagulation versus placebo for heart failure in sinus rhythm. Cochrane Database Syst Rev. 2012 Jun 13;6:CD003336. doi: 10.1002/14651858.CD003336.pub2. Review. PubMed PMID: 22696335. 163: Potpara TS, Polovina MM, Licina MM, Stojanovic RM, Prostran MS, Lip GY. Novel oral anticoagulants for stroke prevention in atrial fibrillation: focus on apixaban. Adv Ther. 2012 Jun;29(6):491-507. doi: 10.1007/s12325-012-0026-8. Epub 2012 Jun 7. Review. PubMed PMID: 22684583. 164: Roldán V, Marín F, Díaz J, Gallego P, Jover E, Romera M, Manzano-Fernández S, Casas T, Valdés M, Vicente V, Lip GY. High sensitivity cardiac troponin T and interleukin-6 predict adverse cardiovascular events and mortality in anticoagulated patients with atrial fibrillation. J Thromb Haemost. 2012 Aug;10(8):1500-7. doi: 10.1111/j.1538-7836.2012.04812.x. PubMed PMID: 22681487. 165: Shantsila E, Wrigley BJ, Blann AD, Gill PS, Lip GY. A contemporary view on endothelial function in heart failure. Eur J Heart Fail. 2012 Aug;14(8):873-81. doi: 10.1093/eurjhf/hfs066. Epub 2012 Jun 7. Review. PubMed PMID: 22677484. 166: Adlan AM, Lip GY. Role of the CHADS2 score in acute coronary syndromes: with or without atrial fibrillation. Chest. 2012 Jun;141(6):1375-6. doi: 10.1378/chest.11-2780. PubMed PMID: 22670015. 167: Guo Y, Lip GY, Apostolakis S. Bleeding risk assessment and management in atrial fibrillation patients. Key messages for clinical practice from the European Heart Rhythm Association position statement. Pol Arch Med Wewn. 2012;122(5):235-42. Review. PubMed PMID: 22660688. 168: Friberg L, Benson L, Rosenqvist M, Lip GY. Assessment of female sex as a risk factor in atrial fibrillation in Sweden: nationwide retrospective cohort study. BMJ. 2012 May 30;344:e3522. doi: 10.1136/bmj.e3522. PubMed PMID: 22653980; 24 PubMed Central PMCID: PMC3365143. 169: Lip G. An audience with... Gregory Lip. Interview by Asher Mullard. Nat Rev Drug Discov. 2012 Jun 1;11(6):434. doi: 10.1038/nrd3752. PubMed PMID: 22653207. 170: Guo Y, Lip GY, Apostolakis S. How early is early enough to prevent stroke in atrial fibrillation? Expert Rev Cardiovasc Ther. 2012 May;10(5):585-8. doi: 10.1586/erc.12.36. PubMed PMID: 22651834. 171: McCaffer C, Lip G, Bachoo P, Rajagopalan S. Infective endocarditis causing ulnar mycotic aneurysm and compartment syndrome. Postgrad Med J. 2012 Jul;88(1041):426-7. doi: 10.1136/postgradmedj-2012-130760. Epub 2012 May 28. PubMed PMID: 22641766. 172: Apostolakis S, Lip GY. Novel oral anticoagulants: focus on the direct factor Xa inhibitor darexaban. Expert Opin Investig Drugs. 2012 Jul;21(7):1057-64. doi: 10.1517/13543784.2012.689286. Epub 2012 May 23. Review. PubMed PMID: 22616561. 173: McMurray JJ, Adamopoulos S, Anker SD, Auricchio A, Böhm M, Dickstein K, Falk V, Filippatos G, Fonseca C, Gomez-Sanchez MA, Jaarsma T, Køber L, Lip GY, Maggioni AP, Parkhomenko A, Pieske BM, Popescu BA, Rønnevik PK, Rutten FH, Schwitter J, Seferovic P, Stepinska J, Trindade PT, Voors AA, Zannad F, Zeiher A; ESC Committee for Practice Guidelines. ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure 2012: The Task Force for the Diagnosis and Treatment of Acute and Chronic Heart Failure 2012 of the European Society of Cardiology. Developed in collaboration with the Heart Failure Association (HFA) of the ESC. Eur Heart J. 2012 Jul;33(14):1787-847. doi: 10.1093/eurheartj/ehs104. Epub 2012 May 19. Erratum in: Eur Heart J. 2013 Jan;34(2):158. PubMed PMID: 22611136. 174: Lip GY, Ponikowski P, Andreotti F, Anker SD, Filippatos G, Homma S, Morais J, Pullicino P, Rasmussen LH, Marin F, Lane DA; ESC Task Force. Thrombo-embolism and antithrombotic therapy for heart failure in sinus rhythm. A joint consensus document from the ESC Heart Failure Association and the ESC Working Group on Thrombosis. Eur J Heart Fail. 2012 Jul;14(7):681-95. doi: 10.1093/eurjhf/hfs073. Epub 2012 May 19. Review. PubMed PMID: 22611046. 175: Jover E, Roldán V, Gallego P, Hernández-Romero D, Valdés M, Vicente V, Lip GY, Marín F. Predictive value of the CHA2DS2-VASc score in atrial fibrillation 25 patients at high risk for stroke despite oral anticoagulation. Rev Esp Cardiol (Engl Ed). 2012 Jul;65(7):627-33. doi: 10.1016/j.recesp.2012.02.017. Epub 2012 May 18. English, Spanish. PubMed PMID: 22609214. 176: Roalfe AK, Bryant TL, Davies MH, Hackett TG, Saba S, Fletcher K, Lip GY, Hobbs FD, Mant J; BAFTA investigators. A cross-sectional study of quality of life in an elderly population (75 years and over) with atrial fibrillation: secondary analysis of data from the Birmingham Atrial Fibrillation Treatment of the Aged study. Europace. 2012 Oct;14(10):1420-7. Epub 2012 May 10. PubMed PMID: 22581625. 177: Olesen JB, Lip GY, Lane DA, Køber L, Hansen ML, Karasoy D, Hansen CM, Gislason GH, Torp-Pedersen C. Vascular disease and stroke risk in atrial fibrillation: a nationwide cohort study. Am J Med. 2012 Aug;125(8):826.e13-23. doi: 10.1016/j.amjmed.2011.11.024. Epub 2012 May 10. PubMed PMID: 22579139. 178: Lip GY, Larsen TB, Skjøth F, Rasmussen LH. Indirect comparisons of new oral anticoagulant drugs for efficacy and safety when used for stroke prevention in atrial fibrillation. J Am Coll Cardiol. 2012 Aug 21;60(8):738-46. doi: 10.1016/j.jacc.2012.03.019. Epub 2012 May 9. PubMed PMID: 22575324. 179: Easton JD, Lopes RD, Bahit MC, Wojdyla DM, Granger CB, Wallentin L, Alings M, Goto S, Lewis BS, Rosenqvist M, Hanna M, Mohan P, Alexander JH, Diener HC; ARISTOTLE Committees and Investigators. Apixaban compared with warfarin in patients with atrial fibrillation and previous stroke or transient ischaemic attack: a subgroup analysis of the ARISTOTLE trial. Lancet Neurol. 2012 Jun;11(6):503-11. doi: 10.1016/S1474-4422(12)70092-3. Epub 2012 May 8. Erratum in: Lancet Neurol. 2012 Dec;11(12):1021. PubMed PMID: 22572202. 180: Marín F, Roldán V, Lip GY. Dabigatran for the prevention of stroke in atrial fibrillation: is RE-LY reliable? Expert Opin Pharmacother. 2012 Jun;13(8):1087-90. doi: 10.1517/14656566.2012.688954. Epub 2012 May 9. PubMed PMID: 22568622. 181: Homma S, Thompson JL, Pullicino PM, Levin B, Freudenberger RS, Teerlink JR, Ammon SE, Graham S, Sacco RL, Mann DL, Mohr JP, Massie BM, Labovitz AJ, Anker SD, Lok DJ, Ponikowski P, Estol CJ, Lip GY, Di Tullio MR, Sanford AR, Mejia V, Gabriel AP, del Valle ML, Buchsbaum R; WARCEF Investigators. Warfarin and aspirin in patients with heart failure and sinus rhythm. N Engl J Med. 2012 May 17;366(20):1859-69. doi: 10.1056/NEJMoa1202299. Epub 2012 May 2. PubMed PMID: 22551105. 26 182: Boggon R, Lip GY, Gallagher AM, van Staa TP. Resource utilization and outcomes in patients with atrial fibrillation: a case control study. Appl Health Econ Health Policy. 2012 Jul 1;10(4):249-59. doi: 10.2165/11599940-000000000-00000. PubMed PMID: 22540235. 183: Kendall H, Marley A, Patel JV, Khan JM, Blann AD, Lip GY, Dwivedi G. Hospital delay in South Asian patients with acute ST-elevation myocardial infarction in the UK. Eur J Prev Cardiol. 2012 Apr 26. [Epub ahead of print] PubMed PMID: 22539810. 184: Shantsila E, Montoro-García S, Tapp LD, Apostolakis S, Wrigley BJ, Lip GY. Fibrinolytic status in acute coronary syndromes: evidence of differences in relation to clinical features and pathophysiological pathways. Thromb Haemost. 2012 Jul;108(1):32-40. doi: 10.1160/TH12-01-0011. Epub 2012 Apr 27. PubMed PMID: 22538774. 185: Larsen TB, Lip GY, Skjøth F, Due KM, Overvad K, Hvilsted Rasmussen L. Added predictive ability of the CHA2DS2VASc risk score for stroke and death in patients with atrial fibrillation: the prospective Danish Diet, Cancer, and Health cohort study. Circ Cardiovasc Qual Outcomes. 2012 May;5(3):335-42. doi: 10.1161/CIRCOUTCOMES.111.964023. Epub 2012 Apr 24. PubMed PMID: 22534406. 186: Calvert M, Duffy H, Freemantle N, Davis R, Lip GY, Gill P. Population health status of South Asian and African-Caribbean communities in the United Kingdom. BMC Health Serv Res. 2012 Apr 25;12:101. doi: 10.1186/1472-6963-12-101. PubMed PMID: 22533538; PubMed Central PMCID: PMC3349523. 187: Lip GY, Proclemer A, Dagres N, Bongiorni MG, Lewalter T, Blomström-Lundqvist C; Scientific Initiative Committee, European Heart Rhythm Association. Periprocedural anticoagulation therapy for devices and atrial fibrillation ablation. Europace. 2012 May;14(5):741-4. doi: 10.1093/europace/eus105. PubMed PMID: 22532381. 188: Lip GY. What is the most effective and safest delivery of thromboprophylaxis in atrial fibrillation? J R Coll Physicians Edinb. 2012;42 Suppl 18:35-44. doi: 10.4997/JRCPE.2012.S04. PubMed PMID: 22518392. 27 189: Shantsila E, Wrigley BJ, Shantsila A, Tapp LD, Gill PS, Lip GY. Monocyte-derived and CD34+/KDR+ endothelial progenitor cells in heart failure. J Thromb Haemost. 2012 Jul;10(7):1252-61. doi: 10.1111/j.1538-7836.2012.04753.x. PubMed PMID: 22519984. 190: Friberg L, Rosenqvist M, Lip GY. Net clinical benefit of warfarin in patients with atrial fibrillation: a report from the Swedish atrial fibrillation cohort study. Circulation. 2012 May 15;125(19):2298-307. doi: 10.1161/CIRCULATIONAHA.111.055079. Epub 2012 Apr 18. PubMed PMID: 22514252. 191: Foley J, Lip GY. Do the current atrial fibrillation guidelines for stroke prevention need to be changed with the availability of new data on the new oral anticoagulants? Int J Clin Pract. 2012 May;66(5):422-4. doi: 10.1111/j.1742-1241.2011.02815.x. PubMed PMID: 22512602. 192: De Caterina R, Husted S, Wallentin L, Andreotti F, Arnesen H, Bachmann F, Baigent C, Huber K, Jespersen J, Kristensen SD, Lip GY, Morais J, Rasmussen LH, Siegbahn A, Verheugt FW, Weitz JI; Coordinating Committee. New oral anticoagulants in atrial fibrillation and acute coronary syndromes: ESC Working Group on Thrombosis-Task Force on Anticoagulants in Heart Disease position paper. J Am Coll Cardiol. 2012 Apr 17;59(16):1413-25. doi: 10.1016/j.jacc.2012.02.008. Review. PubMed PMID: 22497820. 193: Shantsila A, Lane DA, Beevers DG, Lip GY. Lack of impact of pulse pressure on outcomes in patients with malignant phase hypertension: the West Birmingham Malignant Hypertension study. J Hypertens. 2012 May;30(5):974-9. doi: 10.1097/HJH.0b013e3283526e47. PubMed PMID: 22495136. 194: Bennett PC, Gill PS, Silverman S, Blann AD, Balakrishnan B, Lip GY. Ethnic/racial differences in circulating markers of angiogenesis and their association with cardiovascular risk factors and cardiovascular disease. Int J Cardiol. 2012 Apr 9. [Epub ahead of print] PubMed PMID: 22494858. 195: Davis RC, Hobbs FD, Kenkre JE, Roalfe AK, Iles R, Lip GY, Davies MK. Prevalence of atrial fibrillation in the general population and in high-risk groups: the ECHOES study. Europace. 2012 Nov;14(11):1553-9. doi: 10.1093/europace/eus087. Epub 2012 Apr 5. PubMed PMID: 22490371. 196: Olesen JB, Torp-Pedersen C, Hansen ML, Lip GY. The value of the CHA2DS2-VASc 28 score for refining stroke risk stratification in patients with atrial fibrillation with a CHADS2 score 0-1: a nationwide cohort study. Thromb Haemost. 2012 Jun;107(6):1172-9. doi: 10.1160/TH12-03-0175. Epub 2012 Apr 3. PubMed PMID: 22473219. 197: Tchaikovski V, Lip GY. Angiotensin receptor blockers and tumorigenesis: something to be (or not to be) concerned about? Curr Hypertens Rep. 2012 Jun;14(3):183-92. doi: 10.1007/s11906-012-0263-x. Review. PubMed PMID: 22467342. 198: Fauchier L, Pellegrin C, Bernard A, Clementy N, Angoulvant D, Lip GY, Babuty D. Comparison of frequency of major adverse events in patients with atrial fibrillation receiving bare-metal versus drug-eluting stents in their coronary arteries. Am J Cardiol. 2012 Jul 1;110(1):7-12. doi: 10.1016/j.amjcard.2012.02.042. Epub 2012 Mar 29. PubMed PMID: 22463838. 199: Lip GY, Brechin CM, Lane DA. The global burden of atrial fibrillation and stroke: a systematic review of the epidemiology of atrial fibrillation in regions outside North America and Europe. Chest. 2012 Dec;142(6):1489-98. doi: 10.1378/chest.11-2888. Review. PubMed PMID: 22459778. 200: Lewalter T, Morgan J, Halimi F, Lip G, Dagres N, Blomström-Lundqvist C; Scientific Initiative Committee, European Heart Rhythm Association. Monitoring in the management of atrial fibrillation. Europace. 2012 Apr;14(4):591-2. doi: 10.1093/europace/eus073. PubMed PMID: 22454456. 201: Lahtela H, Rubboli A, Schlitt A, Karjalainen PP, Niemelä M, Vikman S, Puurunen M, Weber M, Valencia J, Biancari F, Lip GY, Airaksinen KE; AFCAS (Management of patients with Atrial Fibrillation undergoing Coronary Artery Stenting) study group. Heparin bridging vs. uninterrupted oral anticoagulation in patients with Atrial Fibrillation undergoing Coronary Artery Stenting. Results from the AFCAS registry. Circ J. 2012;76(6):1363-8. Epub 2012 Mar 9. PubMed PMID: 22447005. 202: Patel JV, Lip GY, Prabharkaran D, Reddy KS, Gill PS, Hughes EA. Anthropometric discriminators of the risk of high blood pressure amongst public schoolchildren in Gujarat, India. Int J Clin Pract. 2012 Apr;66(4):418-20. doi: 10.1111/j.1742-1241.2011.02875.x. PubMed PMID: 22420501. 203: Karthikeyan VJ, Lane DA, Beevers DG, Lip GY, Blann AD. Matrix 29 metalloproteinases and their tissue inhibitors in hypertension-related pregnancy complications. J Hum Hypertens. 2013 Feb;27(2):72-8. doi: 10.1038/jhh.2012.8. Epub 2012 Mar 15. PubMed PMID: 22418748. 204: Butt M, Dwivedi G, Shantsila A, Khair OA, Lip GY. Left ventricular systolic and diastolic function in obstructive sleep apnea: impact of continuous positive airway pressure therapy. Circ Heart Fail. 2012 Mar 1;5(2):226-33. doi: 10.1161/CIRCHEARTFAILURE.111.964106. Epub 2012 Mar 13. PubMed PMID: 22414938. 205: Ahmad Y, Lip GY. Stroke Prevention in Atrial Fibrillation: Where are We Now? Clin Med Insights Cardiol. 2012;6:65-78. doi: 10.4137/CMC.S8976. Epub 2012 Feb 23. PubMed PMID: 22408371; PubMed Central PMCID: PMC3296491. 206: Hankey GJ, Patel MR, Stevens SR, Becker RC, Breithardt G, Carolei A, Diener HC, Donnan GA, Halperin JL, Mahaffey KW, Mas JL, Massaro A, Norrving B, Nessel CC, Paolini JF, Roine RO, Singer DE, Wong L, Califf RM, Fox KA, Hacke W; ROCKET AF Steering Committee Investigators. Rivaroxaban compared with warfarin in patients with atrial fibrillation and previous stroke or transient ischaemic attack: a subgroup analysis of ROCKET AF. Lancet Neurol. 2012 Apr;11(4):315-22. doi: 10.1016/S1474-4422(12)70042-X. Epub 2012 Mar 7. PubMed PMID: 22402056. 207: Shantsila A, Lip GY. Highlights of the American Heart Association Scientific Sessions 2011: a focus on ATLAS-TIMI 51, TRACER and PALLAS. Expert Rev Cardiovasc Ther. 2012 Mar;10(3):305-7. doi: 10.1586/erc.11.192. PubMed PMID: 22390801. 208: Kuzniatsova N, Shantsila E, Blann A, Lip GY. A contemporary viewpoint on 'aspirin resistance'. Ann Med. 2012 Dec;44(8):773-83. doi: 10.3109/07853890.2011.605388. Epub 2012 Mar 1. Review. PubMed PMID: 22380694. 209: Boriani G, Santini M, Lunati M, Gasparini M, Proclemer A, Landolina M, Padeletti L, Botto GL, Capucci A, Bianchi S, Biffi M, Ricci RP, Vimercati M, Grammatico A, Lip GY; Italian ClinicalService Project. Improving thromboprophylaxis using atrial fibrillation diagnostic capabilities in implantable cardioverter-defibrillators: the multicentre Italian ANGELS of AF Project. Circ Cardiovasc Qual Outcomes. 2012 Mar 1;5(2):182-8. doi: 10.1161/CIRCOUTCOMES.111.964205. Epub 2012 Feb 28. PubMed PMID: 22373906. 210: Shantsila A, Dwivedi G, Shantsila E, Steeds RP, Beevers G, Lip GY. Vascular ventricular coupling in patients with malignant phase hypertension: the West 30 Birmingham malignant hypertension project. Hypertens Res. 2012 Jul;35(7):725-8. doi: 10.1038/hr.2012.18. Epub 2012 Feb 23. PubMed PMID: 22357519. 211: Shantsila E, Tapp LD, Wrigley BJ, Montoro-Garcia S, Ghattas A, Jaipersad A, Lip GY. The effects of exercise and diurnal variation on monocyte subsets and monocyte-platelet aggregates. Eur J Clin Invest. 2012 Aug;42(8):832-9. doi: 10.1111/j.1365-2362.2012.02656.x. Epub 2012 Feb 22. PubMed PMID: 22356533. 212: Marinskis G, van Erven L, Bongiorni MG, Lip GY, Pison L, Blomström-Lundqvist C; Scientific Initiative Committee, European Heart Rhythm Association. Practices of cardiac implantable electronic device follow-up: results of the European Heart Rhythm Association survey. Europace. 2012 Mar;14(3):423-5. doi: 10.1093/europace/eus020. PubMed PMID: 22355191. 213: Riva N, Lip GY. A new era for anticoagulation in atrial fibrillation. Which anticoagulant should we choose for long‑term prevention of thromboembolic complications in patients with atrial fibrillation? Pol Arch Med Wewn. 2012;122(1-2):45-53. Review. PubMed PMID: 22353706. 214: Lip GY, Camm AJ. Comments on the Spanish Society of Cardiology critical review of the ESC 2010 clinical practice guidelines on atrial fibrillation. Rev Esp Cardiol (Engl Ed). 2012 Apr;65(4):390-1; author reply 391-2. doi: 10.1016/j.recesp.2011.12.007. Epub 2012 Feb 18. PubMed PMID: 22342502. 215: You JJ, Singer DE, Howard PA, Lane DA, Eckman MH, Fang MC, Hylek EM, Schulman S, Go AS, Hughes M, Spencer FA, Manning WJ, Halperin JL, Lip GY; American College of Chest Physicians. Antithrombotic therapy for atrial fibrillation: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. Chest. 2012 Feb;141(2 Suppl):e531S-75S. doi: 10.1378/chest.11-2304. PubMed PMID: 22315271; PubMed Central PMCID: PMC3278056. 216: Gallego P, Roldán V, Torregrosa JM, Gálvez J, Valdés M, Vicente V, Marín F, Lip GY. Relation of the HAS-BLED bleeding risk score to major bleeding, cardiovascular events, and mortality in anticoagulated patients with atrial fibrillation. Circ Arrhythm Electrophysiol. 2012 Apr;5(2):312-8. doi: 10.1161/CIRCEP.111.967000. Epub 2012 Feb 7. PubMed PMID: 22319005. 217: Potpara TS, Polovina MM, Licina MM, Marinkovic JM, Prostran MS, Lip GY. 31 Reliable identification of "truly low" thromboembolic risk in patients initially diagnosed with "lone" atrial fibrillation: the Belgrade atrial fibrillation study. Circ Arrhythm Electrophysiol. 2012 Apr;5(2):319-26. doi: 10.1161/CIRCEP.111.966713. Epub 2012 Feb 8. PubMed PMID: 22319004. 218: Huisman MV, Lip GY, Diener HC, Brueckmann M, van Ryn J, Clemens A. Dabigatran etexilate for stroke prevention in patients with atrial fibrillation: resolving uncertainties in routine practice. Thromb Haemost. 2012 May;107(5):838-47. doi: 10.1160/TH11-10-0718. Epub 2012 Feb 8. Review. PubMed PMID: 22318514. 219: Gluba A, Mikhailidis DP, Lip GY, Hannam S, Rysz J, Banach M. Metabolic syndrome and renal disease. Int J Cardiol. 2013 Apr 5;164(2):141-50. doi: 10.1016/j.ijcard.2012.01.013. Epub 2012 Feb 2. PubMed PMID: 22305775. 220: Diener HC, Eikelboom J, Connolly SJ, Joyner CD, Hart RG, Lip GY, O'Donnell M, Hohnloser SH, Hankey GJ, Shestakovska O, Yusuf S; AVERROES Steering Committee and Investigators. Apixaban versus aspirin in patients with atrial fibrillation and previous stroke or transient ischaemic attack: a predefined subgroup analysis from AVERROES, a randomised trial. Lancet Neurol. 2012 Mar;11(3):225-31. doi: 10.1016/S1474-4422(12)70017-0. Epub 2012 Feb 1. PubMed PMID: 22305462. 221: Banerjee A, Taillandier S, Olesen JB, Lane DA, Lallemand B, Lip GY, Fauchier L. Ejection fraction and outcomes in patients with atrial fibrillation and heart failure: the Loire Valley Atrial Fibrillation Project. Eur J Heart Fail. 2012 Mar;14(3):295-301. doi: 10.1093/eurjhf/hfs005. Epub 2012 Jan 30. PubMed PMID: 22294759. 222: Montoro-García S, Orenes-Piñero E, Marín F, Mariano, Valdés, Lip GY, Shantsila E. Pharmacological modulation of microparticle release: new strategies for the management of atherothrombotic vascular disorders. Curr Pharm Des. 2012;18(6):840-9. Review. PubMed PMID: 22288445. 223: Pamukcu B, Huber K, Lip GY. Antiplatelet therapy in atherothrombotic cardiovascular diseases for primary and secondary prevention: a focus on old and new antiplatelet agents. Curr Pharm Des. 2012;18(6):850-60. PubMed PMID: 22288444. 224: Taillandier S, Olesen JB, Clémenty N, Lagrenade I, Babuty D, Lip GY, 32 Fauchier L. Prognosis in patients with atrial fibrillation and CHA2DS2-VASc Score = 0 in a community-based cohort study. J Cardiovasc Electrophysiol. 2012 Jul;23(7):708-13. doi: 10.1111/j.1540-8167.2011.02257.x. Epub 2012 Jan 23. PubMed PMID: 22268375. 225: Svendsen JH, Goette A, Dobreanu D, Marinskis G, Mabo P, Blomström-Lundqvist C; Scientific Initiative Committee, European Heart Rhythm Association. Outpatient evaluation and management of patients with ventricular premature beats or non-sustained ventricular tachycardia. Europace. 2012 Feb;14(2):294-6. doi: 10.1093/europace/eus009. PubMed PMID: 22266845. 226: Lip GY. Can we predict stroke in atrial fibrillation? Clin Cardiol. 2012 Jan;35 Suppl 1:21-7. doi: 10.1002/clc.20969. Review. PubMed PMID: 22246948. 227: Olesen JB, Gislason GH, Torp-Pedersen C, Lip GY. Atrial fibrillation and vascular disease--a bad combination. Clin Cardiol. 2012 Jan;35 Suppl 1:15-20. doi: 10.1002/clc.20955. Review. PubMed PMID: 22246947. 228: Lip GY. Bleeding risk assessment and management in atrial fibrillation patients. Eur Heart J. 2012 Jan;33(2):147-9. doi: 10.1093/eurheartj/ehr431. PubMed PMID: 22246817. 229: Friberg L, Rosenqvist M, Lip GY. Evaluation of risk stratification schemes for ischaemic stroke and bleeding in 182 678 patients with atrial fibrillation: the Swedish Atrial Fibrillation cohort study. Eur Heart J. 2012 Jun;33(12):1500-10. doi: 10.1093/eurheartj/ehr488. Epub 2012 Jan 13. PubMed PMID: 22246443. 230: Shantsila E, Bialiuk N, Navitski D, Pyrochkin A, Gill PS, Pyrochkin V, Snezhitskiy V, Lip GY. Blood leukocytes in heart failure with preserved ejection fraction: impact on prognosis. Int J Cardiol. 2012 Mar 8;155(2):337-8. doi: 10.1016/j.ijcard.2011.12.048. Epub 2012 Jan 9. PubMed PMID: 22227252. 231: Tapp LD, Shantsila E, Wrigley BJ, Pamukcu B, Lip GY. The CD14++CD16+ monocyte subset and monocyte-platelet interactions in patients with ST-elevation myocardial infarction. J Thromb Haemost. 2012 Jul;10(7):1231-41. doi: 10.1111/j.1538-7836.2011.04603.x. PubMed PMID: 22212813. 33 232: Vemmos K, Ntaios G, Savvari P, Vemmou AM, Koroboki E, Manios E, Kounali A, Lip GY. Stroke aetiology and predictors of outcome in patients with heart failure and acute stroke: a 10-year follow-up study. Eur J Heart Fail. 2012 Feb;14(2):211-8. doi: 10.1093/eurjhf/hfr172. Epub 2011 Dec 26. PubMed PMID: 22200911. 233: Shantsila A, Dwivedi G, Shantsila E, Butt M, Beevers DG, Lip GY. A comprehensive assessment of cardiac structure and function in patients with treated malignant phase hypertension: The West Birmingham Malignant Hypertension project. Int J Cardiol. 2013 Jul 15;167(1):67-72. doi: 10.1016/j.ijcard.2011.11.077. Epub 2011 Dec 20. PubMed PMID: 22192285. 234: Banerjee A, Lane DA, Torp-Pedersen C, Lip GY. Net clinical benefit of new oral anticoagulants (dabigatran, rivaroxaban, apixaban) versus no treatment in a 'real world' atrial fibrillation population: a modelling analysis based on a nationwide cohort study. Thromb Haemost. 2012 Mar;107(3):584-9. doi: 10.1160/TH11-11-0784. Epub 2011 Dec 21. PubMed PMID: 22186961. 235: Manolis AJ, Rosei EA, Coca A, Cifkova R, Erdine SE, Kjeldsen S, Lip GY, Narkiewicz K, Parati G, Redon J, Schmieder R, Tsioufis C, Mancia G. Hypertension and atrial fibrillation: diagnostic approach, prevention and treatment. Position paper of the Working Group 'Hypertension Arrhythmias and Thrombosis' of the European Society of Hypertension. J Hypertens. 2012 Feb;30(2):239-52. doi: 10.1097/HJH.0b013e32834f03bf. Review. PubMed PMID: 22186358. 236: Lip GY. Atrial fibrillation in 2011: Stroke prevention in AF. Nat Rev Cardiol. 2011 Dec 20;9(2):71-3. doi: 10.1038/nrcardio.2011.203. Review. PubMed PMID: 22182957. 237: Kakkar AK, Mueller I, Bassand JP, Fitzmaurice DA, Goldhaber SZ, Goto S, Haas S, Hacke W, Lip GY, Mantovani LG, Verheugt FW, Jamal W, Misselwitz F, Rushton-Smith S, Turpie AG. International longitudinal registry of patients with atrial fibrillation at risk of stroke: Global Anticoagulant Registry in the FIELD (GARFIELD). Am Heart J. 2012 Jan;163(1):13-19.e1. doi: 10.1016/j.ahj.2011.09.011. Epub 2011 Nov 20. PubMed PMID: 22172431. 238: Potpara TS, Lip GY. Treatment pathways for atrial fibrillation: simplifying the approach to thromboprophylaxis. Int J Clin Pract. 2012 Jan;66(1):4-6. doi: 10.1111/j.1742-1241.2011.02816.x. PubMed PMID: 22171898. 34 239: Riva N, Apostolakis S, Lip GY. Oral antithrombotic therapy and gastrointestinal bleeding: the good, the bad and the ugly. Int J Clin Pract. 2012 Jan;66(1):2-4. doi: 10.1111/j.1742-1241.2011.02828.x. PubMed PMID: 22171897. 240: Lip GY, Tse HF, Lane DA. Atrial fibrillation. Lancet. 2012 Feb 18;379(9816):648-61. doi: 10.1016/S0140-6736(11)61514-6. Epub 2011 Dec 11. Review. PubMed PMID: 22166900. 241: Lip GY, Felmeden DC, Dwivedi G. Antiplatelet agents and anticoagulants for hypertension. Cochrane Database Syst Rev. 2011 Dec 7;(12):CD003186. doi: 10.1002/14651858.CD003186.pub3. Review. PubMed PMID: 22161375. 242: Shantsila A, Lip GY. Dronedarone: a new hope for stroke prevention in atrial fibrillation? Am J Cardiovasc Drugs. 2011 Dec 1;11(6):355-6. doi: 10.2165/11595330-000000000-00000. PubMed PMID: 22149314. 243: Diener HC, Weber R, Lip GY, Hohnloser SH. Stroke prevention in atrial fibrillation: do we still need warfarin? Curr Opin Neurol. 2012 Feb;25(1):27-35. doi: 10.1097/WCO.0b013e32834e604a. Review. PubMed PMID: 22143201. 244: Patel JV, Hughes EA, Lip GY, Gill PS. Diabetes Health, Residence & Metabolism in Asians: the DHRMA study, research into foods from the Indian subcontinent - a blinded, randomised, placebo controlled trial. BMC Cardiovasc Disord. 2011 Dec 2;11:70. doi: 10.1186/1471-2261-11-70. PubMed PMID: 22136261; PubMed Central PMCID: PMC3259037. 245: Weijs B, Pisters R, Nieuwlaat R, Breithardt G, Le Heuzey JY, Vardas PE, Limantoro I, Schotten U, Lip GY, Crijns HJ. Idiopathic atrial fibrillation revisited in a large longitudinal clinical cohort. Europace. 2012 Feb;14(2):184-90. doi: 10.1093/europace/eur379. Epub 2011 Dec 1. PubMed PMID: 22135317. 246: Marchesi C, Dentali F, Nicolini E, Maresca AM, Tayebjee MH, Franz M, Guasti L, Venco A, Schiffrin EL, Lip GY, Grandi AM. Plasma levels of matrix metalloproteinases and their inhibitors in hypertension: a systematic review and meta-analysis. J Hypertens. 2012 Jan;30(1):3-16. doi: 10.1097/HJH.0b013e32834d249a. Review. PubMed PMID: 22134384. 35 247: Gill PS, Calvert M, Davis R, Davies MK, Freemantle N, Lip GY. Prevalence of heart failure and atrial fibrillation in minority ethnic subjects: the Ethnic-Echocardiographic Heart of England Screening Study (E-ECHOES). PLoS One. 2011;6(11):e26710. doi: 10.1371/journal.pone.0026710. Epub 2011 Nov 16. PubMed PMID: 22110591; PubMed Central PMCID: PMC3217919. 248: Shantsila E, Lip GY, Gill PS. Systolic heart failure in South Asians. Int J Clin Pract. 2011 Dec;65(12):1274-82. doi: 10.1111/j.1742-1241.2011.02796.x. Review. PubMed PMID: 22093534. 249: Toor IS, Jaumdally R, Lip GY, Pagano D, Dimitri W, Millane T, Varma C. Differences between South Asians and White Europeans in five year outcome following percutaneous coronary intervention. Int J Clin Pract. 2011 Dec;65(12):1259-66. doi: 10.1111/j.1742-1241.2011.02776.x. PubMed PMID: 22093532. 250: Connolly SJ, Camm AJ, Halperin JL, Joyner C, Alings M, Amerena J, Atar D, Avezum Á, Blomström P, Borggrefe M, Budaj A, Chen SA, Ching CK, Commerford P, Dans A, Davy JM, Delacrétaz E, Di Pasquale G, Diaz R, Dorian P, Flaker G, Golitsyn S, Gonzalez-Hermosillo A, Granger CB, Heidbüchel H, Kautzner J, Kim JS, Lanas F, Lewis BS, Merino JL, Morillo C, Murin J, Narasimhan C, Paolasso E, Parkhomenko A, Peters NS, Sim KH, Stiles MK, Tanomsup S, Toivonen L, Tomcsányi J, Torp-Pedersen C, Tse HF, Vardas P, Vinereanu D, Xavier D, Zhu J, Zhu JR, Baret-Cormel L, Weinling E, Staiger C, Yusuf S, Chrolavicius S, Afzal R, Hohnloser SH; PALLAS Investigators. Dronedarone in high-risk permanent atrial fibrillation. N Engl J Med. 2011 Dec 15;365(24):2268-76. doi: 10.1056/NEJMoa1109867. Epub 2011 Nov 14. Erratum in: N Engl J Med. 2012 Feb 16;366(7):672. PubMed PMID: 22082198. 251: Mega JL, Braunwald E, Wiviott SD, Bassand JP, Bhatt DL, Bode C, Burton P, Cohen M, Cook-Bruns N, Fox KA, Goto S, Murphy SA, Plotnikov AN, Schneider D, Sun X, Verheugt FW, Gibson CM; ATLAS ACS 2–TIMI 51 Investigators. Rivaroxaban in patients with a recent acute coronary syndrome. N Engl J Med. 2012 Jan 5;366(1):9-19. doi: 10.1056/NEJMoa1112277. Epub 2011 Nov 13. PubMed PMID: 22077192. 252: Lane DA, Apostolakis S, Boos CJ, Lip GY. Atrial fibrillation (chronic). Clin Evid (Online). 2011 Nov 10;2011. doi:pii: 0217. Review. PubMed PMID: 22075545. 253: Potpara TS, Lip GY. Lone atrial fibrillation: where are we now? Hosp Pract 36 (1995). 2011 Oct;39(4):17-31. doi: 10.3810/hp.2011.10.919. Review. PubMed PMID: 22056820. 254: Lip GY, Andreotti F, Fauchier L, Huber K, Hylek E, Knight E, Lane D, Levi M, Marín F, Palareti G, Kirchhof P; European Heart Rhythm Association. Bleeding risk assessment and management in atrial fibrillation patients. Executive Summary of a Position Document from the European Heart Rhythm Association [EHRA], endorsed by the European Society of Cardiology [ESC] Working Group on Thrombosis. Thromb Haemost. 2011 Dec;106(6):997-1011. doi: 10.1160/TH11-10-0690. Epub 2011 Nov 2. PubMed PMID: 22048796. 255: Kirchhof P, Lip GY, Van Gelder IC, Bax J, Hylek E, Kääb S, Schotten U, Wegscheider K, Boriani G, Ezekowitz M, Diener H, Heidbuchel H, Lane D, Mont L, Willems S, Dorian P, Vardas P, Breithardt G, Camm AJ. Comprehensive risk reduction in patients with atrial fibrillation: Emerging diagnostic and therapeutic options. Executive summary of the report from the 3rd AFNET/EHRA consensus conference. Thromb Haemost. 2011 Dec;106(6):1012-9. doi: 10.1160/TH11-07-0517. Epub 2011 Nov 2. PubMed PMID: 22048744. 256: Shantsila A, Lip GY. Silent cerebral embolism after catheter ablation of atrial fibrillation. Int J Clin Pract. 2012 Feb;66(2):118-20. doi: 10.1111/j.1742-1241.2011.02820.x. Epub 2011 Oct 21. PubMed PMID: 22017668. 257: Potpara TS, Lip GY. Ischemic stroke and atrial fibrillation--a deadly serious combination. Cerebrovasc Dis. 2011;32(5):461-2. doi: 10.1159/000332030. Epub 2011 Oct 14. PubMed PMID: 22005454. 258: Banerjee A, Marín F, Lip GY. A new landscape for stroke prevention in atrial fibrillation: focus on new anticoagulants, antiarrhythmic drugs, and devices. Stroke. 2011 Nov;42(11):3316-22. doi: 10.1161/STROKEAHA.111.617886. Epub 2011 Oct 13. Review. PubMed PMID: 21998051. 259: Potpara TS, Polovina MM, Licina MM, Mujovic NM, Marinkovic JM, Petrovic M, Vujisic-Tesic B, Lip GY. The impact of dilated left atrium on rhythm control in patients with newly diagnosed persistent atrial fibrillation: the Belgrade atrial fibrillation project. Int J Clin Pract. 2011 Nov;65(11):1202-3. doi: 10.1111/j.1742-1241.2011.02772.x. PubMed PMID: 21995698. 260: Foster W, Lip GY, Raza K, Carruthers D, Blann AD. An observational study of 37 endothelial function in early arthritis. Eur J Clin Invest. 2012 May;42(5):510-6. doi: 10.1111/j.1365-2362.2011.02607.x. Epub 2011 Oct 10. PubMed PMID: 21985471. 261: Riva N, Lip GY. Nebivolol for the treatment of heart failure. Expert Opin Investig Drugs. 2011 Dec;20(12):1733-46. doi: 10.1517/13543784.2011.625011. Epub 2011 Oct 8. Review. PubMed PMID: 21980961. 262: Kaireviciute D, Lip GY, Balakrishnan B, Uzdavinys G, Norkunas G, Kalinauskas G, Sirvydis V, Aidietis A, Zanetto U, Sihota H, Maheshwari M, Blann AD. Intracardiac expression of markers of endothelial damage/dysfunction, inflammation, thrombosis, and tissue remodeling, and the development of postoperative atrial fibrillation. J Thromb Haemost. 2011 Dec;9(12):2345-52. doi: 10.1111/j.1538-7836.2011.04523.x. PubMed PMID: 21972893. 263: Wrigley BJ, Lip GY, Shantsila E. The role of monocytes and inflammation in the pathophysiology of heart failure. Eur J Heart Fail. 2011 Nov;13(11):1161-71. doi: 10.1093/eurjhf/hfr122. Epub 2011 Sep 27. Review. PubMed PMID: 21952932. 264: Riva N, Smith DE, Lip GY, Lane DA. Advancing age and bleeding risk are the strongest barriers to anticoagulant prescription in atrial fibrillation. Age Ageing. 2011 Nov;40(6):653-5. doi: 10.1093/ageing/afr128. Epub 2011 Sep 27. PubMed PMID: 21951858. 265: Rubboli A, Dewilde W, Huber K, Eeckhout E, Herzfeld I, Valencia J, Windecker S, Airaksinen KE, Lip GY. The management of patients on oral anticoagulation undergoing coronary stent implantation: a survey among interventional cardiologists from eight European countries. J Interv Cardiol. 2012 Apr;25(2):163-9. doi: 10.1111/j.1540-8183.2011.00683.x. Epub 2011 Sep 26. PubMed PMID: 21950351. 266: Apostolakis S, Lip GY. Stroke prevention in non-valvular atrial fibrillation: can warfarin do better? Thromb Haemost. 2011 Nov;106(5):753-4. doi: 10.1160/TH11-08-0580. Epub 2011 Sep 22. PubMed PMID: 21947024. 267: Potpara TS, Lip GY. New anticoagulation drugs for atrial fibrillation. Clin Pharmacol Ther. 2011 Oct;90(4):502-6. doi: 10.1038/clpt.2011.180. Epub 2011 Aug 10. Review. PubMed PMID: 21934723. 38 268: Pisters R, Olesen JB, Lip GY. The role of echocardiography in stroke risk assessment in patients with atrial fibrillation: is it additive or does it simply echo clinical risk factors? Europace. 2012 Jan;14(1):1-2. doi: 10.1093/europace/eur310. Epub 2011 Sep 20. PubMed PMID: 21933800. 269: Banerjee A, Lip GY. Looking through the PRISM: new insights for young patients with atrial fibrillation and stroke. Cerebrovasc Dis. 2011;32(4):383-4. doi: 10.1159/000331464. Epub 2011 Sep 15. PubMed PMID: 21921602. 270: Shantsila E, Wrigley B, Shantsila A, Tapp LD, Blann AD, Gill PS, Lip GY. Ethnic differences in macrovascular and microvascular function in systolic heart failure. Circ Heart Fail. 2011 Nov;4(6):754-62. doi: 10.1161/CIRCHEARTFAILURE.111.962365. Epub 2011 Sep 13. PubMed PMID: 21914813. 271: Banerjee A, Lip GY. Improving the diagnosis and prognosis of atrial fibrillation in stroke: quo vadis? Eur J Neurol. 2012 Feb;19(2):187-8. doi: 10.1111/j.1468-1331.2011.03516.x. Epub 2011 Sep 14. PubMed PMID: 21914055. 272: Huber K, Airaksinen KJ, Cuisset T, Marín F, Rubboli A, Lip GY. Antithrombotic therapy in patients with atrial fibrillation undergoing coronary stenting: similarities and dissimilarities between North America and Europe. Thromb Haemost. 2011 Oct;106(4):569-71. doi: 10.1160/TH11-08-0602. Epub 2011 Sep 12. PubMed PMID: 21909592. 273: Steg PG, Mehta SR, Jukema JW, Lip GY, Gibson CM, Kovar F, Kala P, Garcia-Hernandez A, Renfurm RW, Granger CB; RUBY-1 Investigators. RUBY-1: a randomized, double-blind, placebo-controlled trial of the safety and tolerability of the novel oral factor Xa inhibitor darexaban (YM150) following acute coronary syndrome. Eur Heart J. 2011 Oct;32(20):2541-54. doi: 10.1093/eurheartj/ehr334. Epub 2011 Aug 30. PubMed PMID: 21878434; PubMed Central PMCID: PMC3295208. 274: Granger CB, Alexander JH, McMurray JJ, Lopes RD, Hylek EM, Hanna M, Al-Khalidi HR, Ansell J, Atar D, Avezum A, Bahit MC, Diaz R, Easton JD, Ezekowitz JA, Flaker G, Garcia D, Geraldes M, Gersh BJ, Golitsyn S, Goto S, Hermosillo AG, Hohnloser SH, Horowitz J, Mohan P, Jansky P, Lewis BS, Lopez-Sendon JL, Pais P, Parkhomenko A, Verheugt FW, Zhu J, Wallentin L; ARISTOTLE Committees and Investigators. Apixaban versus warfarin in patients with atrial fibrillation. N Engl J Med. 2011 Sep 15;365(11):981-92. doi: 10.1056/NEJMoa1107039. Epub 2011 Aug 27. PubMed PMID: 21870978. 39 275: Patel MR, Mahaffey KW, Garg J, Pan G, Singer DE, Hacke W, Breithardt G, Halperin JL, Hankey GJ, Piccini JP, Becker RC, Nessel CC, Paolini JF, Berkowitz SD, Fox KA, Califf RM; ROCKET AF Investigators. Rivaroxaban versus warfarin in nonvalvular atrial fibrillation. N Engl J Med. 2011 Sep 8;365(10):883-91. doi: 10.1056/NEJMoa1009638. Epub 2011 Aug 10. PubMed PMID: 21830957. 276: Smith DE, Lip GY, Lane DA. Strategies to improve oral anticoagulation management. Chest. 2011 Aug;140(2):281-2. doi: 10.1378/chest.11-0418. PubMed PMID: 21813523. 277: Lip GY. Stroke in atrial fibrillation: epidemiology and thromboprophylaxis. J Thromb Haemost. 2011 Jul;9 Suppl 1:344-51. doi: 10.1111/j.1538-7836.2011.04302.x. Review. PubMed PMID: 21781271. 278: Montoro-García S, Marín F, Roldán V, Lip GY. Is plasminogen activator inhibitor-1 (PAI-1) a surrogate marker of vascular damage? Thromb Res. 2011 Dec;128(6):601-2. doi: 10.1016/j.thromres.2011.07.005. Epub 2011 Jul 30. PubMed PMID: 21803401. 279: Banerjee A, Lip GY. Intracerebral hemorrhage and warfarin: perceived versus actual risk. Stroke. 2011 Sep;42(9):2383-4. doi: 10.1161/STROKEAHA.111.626739. Epub 2011 Jul 28. PubMed PMID: 21799157. 280: Kirchhof P, Lip GY, Van Gelder IC, Bax J, Hylek E, Kaab S, Schotten U, Wegscheider K, Boriani G, Brandes A, Ezekowitz M, Diener H, Haegeli L, Heidbuchel H, Lane D, Mont L, Willems S, Dorian P, Aunes-Jansson M, Blomstrom-Lundqvist C, Borentain M, Breitenstein S, Brueckmann M, Cater N, Clemens A, Dobrev D, Dubner S, Edvardsson NG, Friberg L, Goette A, Gulizia M, Hatala R, Horwood J, Szumowski L, Kappenberger L, Kautzner J, Leute A, Lobban T, Meyer R, Millerhagen J, Morgan J, Muenzel F, Nabauer M, Baertels C, Oeff M, Paar D, Polifka J, Ravens U, Rosin L, Stegink W, Steinbeck G, Vardas P, Vincent A, Walter M, Breithardt G, Camm AJ. Comprehensive risk reduction in patients with atrial fibrillation: emerging diagnostic and therapeutic options--a report from the 3rd Atrial Fibrillation Competence NETwork/European Heart Rhythm Association consensus conference. Europace. 2012 Jan;14(1):8-27. doi: 10.1093/europace/eur241. Epub 2011 Jul 26. Review. PubMed PMID: 21791573; PubMed Central PMCID: PMC3236658. 281: Olesen JB, Lip GY, Lindhardsen J, Lane DA, Ahlehoff O, Hansen ML, Raunsø J, Tolstrup JS, Hansen PR, Gislason GH, Torp-Pedersen C. Risks of thromboembolism 40 and bleeding with thromboprophylaxis in patients with atrial fibrillation: A net clinical benefit analysis using a 'real world' nationwide cohort study. Thromb Haemost. 2011 Oct;106(4):739-49. doi: 10.1160/TH11-05-0364. Epub 2011 Jul 20. PubMed PMID: 21789337. 282: Lip GY. The role of aspirin for stroke prevention in atrial fibrillation. Nat Rev Cardiol. 2011 Jul 26;8(10):602-6. doi: 10.1038/nrcardio.2011.112. PubMed PMID: 21788962. 283: Butt M, Khair OA, Dwivedi G, Shantsila A, Shantsila E, Lip GY. Myocardial perfusion by myocardial contrast echocardiography and endothelial dysfunction in obstructive sleep apnea. Hypertension. 2011 Sep;58(3):417-24. doi: 10.1161/HYPERTENSIONAHA.111.170910. Epub 2011 Jul 11. PubMed PMID: 21747042. 284: Kozlowski D, Budrejko S, Lip GY, Mikhailidis DP, Rysz J, Raczak G, Banach M. Dronedarone: an overview. Ann Med. 2012 Feb;44(1):60-72. doi: 10.3109/07853890.2011.594808. Epub 2011 Jul 11. Review. PubMed PMID: 21745093. 285: Andersen LV, Mortensen LS, Lip GY, Lindholt JS, Faergeman O, Henneberg EW, Frost L. Atrial fibrillation and upper limb thromboembolectomy: a national cohort study. J Thromb Haemost. 2011 Sep;9(9):1738-43. doi: 10.1111/j.1538-7836.2011.04435.x. PubMed PMID: 21736696. 286: Khoo CW, Krishnamoorthy S, Lim HS, Lip GY. Atrial fibrillation, arrhythmia burden and thrombogenesis. Int J Cardiol. 2012 Jun 14;157(3):318-23. doi: 10.1016/j.ijcard.2011.06.088. Epub 2011 Jul 2. Review. PubMed PMID: 21726909. 287: Lip GY, Apostolakis S. Atrial fibrillation (acute onset). Clin Evid (Online). 2011 Feb 15;2011. doi:pii: 0210. PubMed PMID: 21718559; PubMed Central PMCID: PMC3275309. 288: Marín F, Roldán V, Martínez JG, Hernández-Madrid A, Hernández-Romero D, Ortego M, Ibáñez A, Marín-Marín I, Navarro X, Lip GY, Moro C. Influence of cardiac resynchronization therapy on indices of inflammation, the prothrombotic state and tissue remodeling in systolic heart failure: a pilot study. Thromb Res. 2011 Oct;128(4):391-4. doi: 10.1016/j.thromres.2011.05.022. Epub 2011 Jun 26. PubMed PMID: 21708399. 41 289: Biancari F, Airaksinen KE, Lip GY. Benefits and risks of using clopidogrel before coronary artery bypass surgery: systematic review and meta-analysis of randomized trials and observational studies. J Thorac Cardiovasc Surg. 2012 Mar;143(3):665-675.e4. doi: 10.1016/j.jtcvs.2011.01.069. Epub 2011 Jun 24. Review. PubMed PMID: 21703636. 290: Hobbs FD, Roalfe AK, Lip GY, Fletcher K, Fitzmaurice DA, Mant J; Birmingham Atrial Fibrillation in the Aged Investigators and Midland Research Practices Consortium Network. Performance of stroke risk scores in older people with atrial fibrillation not taking warfarin: comparative cohort study from BAFTA trial. BMJ. 2011 Jun 23;342:d3653. doi: 10.1136/bmj.d3653. PubMed PMID: 21700651; PubMed Central PMCID: PMC3121229. 291: Montoro-García S, Shantsila E, Marín F, Blann A, Lip GY. Circulating microparticles: new insights into the biochemical basis of microparticle release and activity. Basic Res Cardiol. 2011 Nov;106(6):911-23. doi: 10.1007/s00395-011-0198-4. Epub 2011 Jun 21. PubMed PMID: 21691898. 292: Banerjee A, Marín F, Lip GY. The improved but unfinished business of stroke risk stratification in atrial fibrillation. Rev Esp Cardiol. 2011 Aug;64(8):639-41. doi: 10.1016/j.recesp.2011.04.005. Epub 2011 Jun 17. English, Spanish. PubMed PMID: 21684058. 293: Airaksinen KE, Biancari F, Karjalainen P, Mikkola R, Kuttila K, Porela P, Laitio T, Lip GY. Safety of coronary artery bypass surgery during therapeutic oral anticoagulation. Thromb Res. 2011 Nov;128(5):435-9. doi: 10.1016/j.thromres.2011.05.021. Epub 2011 Jun 17. PubMed PMID: 21683988. 294: Olesen JB, Fauchier L, Lane DA, Taillandier S, Lip GY. Risk factors for stroke and thromboembolism in relation to age among patients with atrial fibrillation: the Loire Valley Atrial Fibrillation Project. Chest. 2012 Jan;141(1):147-53. doi: 10.1378/chest.11-0862. Epub 2011 Jun 16. PubMed PMID: 21680645. 295: Banerjee A, Lane DA, Lip GY. Bleeding risk with oral anticoagulation--new frontiers and new questions. Int J Clin Pract. 2011 Jul;65(7):719-21. doi: 10.1111/j.1742-1241.2011.02716.x. PubMed PMID: 21676114. 296: Violi F, Lip GY, Basili S. Peripheral artery disease and atrial 42 fibrillation: a potentially dangerous combination. Intern Emerg Med. 2012 Jun;7(3):213-8. doi: 10.1007/s11739-011-0637-0. Epub 2011 Jun 11. Review. PubMed PMID: 21667071. 297: Bennett PC, Lip GY, Silverman S, Blann AD, Gill PS. Validation of the Edinburgh Claudication Questionnaire in 1st generation Black African-Caribbean and South Asian UK migrants: a sub-study to the Ethnic-Echocardiographic Heart of England Screening (E-ECHOES) study. BMC Med Res Methodol. 2011 Jun 3;11:85. doi: 10.1186/1471-2288-11-85. PubMed PMID: 21639887; PubMed Central PMCID: PMC3128858. 298: Pamukcu B, Lip GY, Shantsila E. The nuclear factor--kappa B pathway in atherosclerosis: a potential therapeutic target for atherothrombotic vascular disease. Thromb Res. 2011 Aug;128(2):117-23. doi: 10.1016/j.thromres.2011.03.025. Epub 2011 Jun 1. Review. PubMed PMID: 21636112. 299: Olesen JB, Lip GY, Hansen PR, Lindhardsen J, Ahlehoff O, Andersson C, Weeke P, Hansen ML, Gislason GH, Torp-Pedersen C. Bleeding risk in 'real world' patients with atrial fibrillation: comparison of two established bleeding prediction schemes in a nationwide cohort. J Thromb Haemost. 2011 Aug;9(8):1460-7. doi: 10.1111/j.1538-7836.2011.04378.x. PubMed PMID: 21624047. 300: Potpara TS, Stankovic GR, Beleslin BD, Polovina MM, Marinkovic JM, Ostojic MC, Lip GY. A 12-year follow-up study of patients with newly diagnosed lone atrial fibrillation: implications of arrhythmia progression on prognosis: the Belgrade Atrial Fibrillation study. Chest. 2012 Feb;141(2):339-47. doi: 10.1378/chest.11-0340. Epub 2011 May 26. PubMed PMID: 21622553. 301: Karthikeyan VJ, Lip GY. Endothelial damage/dysfunction and hypertension in pregnancy. Front Biosci (Elite Ed). 2011 Jun 1;3:1100-8. Review. PubMed PMID: 21622117. 302: Damman K, Ng Kam Chuen MJ, MacFadyen RJ, Lip GY, Gaze D, Collinson PO, Hillege HL, van Oeveren W, Voors AA, van Veldhuisen DJ. Volume status and diuretic therapy in systolic heart failure and the detection of early abnormalities in renal and tubular function. J Am Coll Cardiol. 2011 May 31;57(22):2233-41. doi: 10.1016/j.jacc.2010.10.065. PubMed PMID: 21616283. 303: Montoro-García S, Lip GY, Shantsila E. Atorvastatin and its collateral effects on microparticles. Thromb Haemost. 2011 Aug;106(2):185-6. doi: 43 10.1160/TH11-05-0335. Epub 2011 May 26. PubMed PMID: 21614421. 304: Ogilvie IM, Welner SA, Cowell W, Lip GY. Ischaemic stroke and bleeding rates in 'real-world' atrial fibrillation patients. Thromb Haemost. 2011 Jul;106(1):34-44. doi: 10.1160/TH10-10-0674. Epub 2011 May 26. Review. PubMed PMID: 21614409. 305: Karthikeyan VJ, Lip GY, Baghdadi S, Lane DA, Beevers DG, Blann AD. Angiogenin and hemoxygenase in pregnancy: influence of hypertension. Angiology. 2012 Apr;63(3):194-8. doi: 10.1177/0003319711410308. Epub 2011 May 20. PubMed PMID: 21602256. 306: Beevers DG, Lip GY. Aortic coarctation and twin pregnancy. J Paediatr Child Health. 2011 May;47(5):316. doi: 10.1111/j.1440-1754.2011.02092.x. PubMed PMID: 21599787. 307: Olesen JB, Lip GY, Lane DA. An epidemic of atrial fibrillation? Europace. 2011 Aug;13(8):1059-60. doi: 10.1093/europace/eur141. Epub 2011 May 18. PubMed PMID: 21593039. 308: Potpara TS, Marinkovic JM, Polovina MM, Stankovic GR, Seferovic PM, Ostojic MC, Lip GY. Gender-related differences in presentation, treatment and long-term outcome in patients with first-diagnosed atrial fibrillation and structurally normal heart: the Belgrade atrial fibrillation study. Int J Cardiol. 2012 Nov 1;161(1):39-44. doi: 10.1016/j.ijcard.2011.04.022. Epub 2011 May 12. PubMed PMID: 21570138. 309: Muñoz-Esparza C, Jover E, Hernández-Romero D, Saura D, Valdés M, Lip GY, Marín F. Interactions between clopidogrel and proton pump inhibitors: a review of evidence. Curr Med Chem. 2011;18(16):2386-400. Review. PubMed PMID: 21568918. 310: Patel JV, Gill PS, Chackathayil J, Ojukwu H, Stemman P, Sheldon L, Meelu S, Lane DA, Tracey I, Lip GY, Hughes EA. Short-term effects of screening for cardiovascular risk in the deaf community: a pilot study. Cardiol Res Pract. 2011 Apr 4;2011:493546. doi: 10.4061/2011/493546. PubMed PMID: 21559268; PubMed Central PMCID: PMC3087949. 311: Blann AD, Balakrishnan B, Shantsila E, Ryan P, Lip GY. Endothelial 44 progenitor cells and circulating endothelial cells in early prostate cancer: a comparison with plasma vascular markers. Prostate. 2011 Jul;71(10):1047-53. doi: 10.1002/pros.21319. Epub 2010 Dec 28. PubMed PMID: 21557269. 312: Karthikeyan VJ, Lip GY, Baghdadi S, Lane DA, Beevers DG, Blann AD. Soluble Fas and Fas ligand in pregnancy: influence of hypertension. Angiology. 2012 Jan;63(1):35-8. doi: 10.1177/0003319711406901. Epub 2011 May 8. PubMed PMID: 21555306. 313: Ding ZX, Lip G, Chong V. Idiopathic orbital pseudotumour. Clin Radiol. 2011 Sep;66(9):886-92. doi: 10.1016/j.crad.2011.03.018. Epub 2011 May 4. Review. PubMed PMID: 21546008. 314: Ogilvie IM, Welner SA, Cowell W, Lip GY. Characterization of the proportion of untreated and antiplatelet therapy treated patients with atrial fibrillation. Am J Cardiol. 2011 Jul 1;108(1):151-61. doi: 10.1016/j.amjcard.2011.02.353. Epub 2011 May 3. Review. PubMed PMID: 21545990. 315: Rubboli A, Kovacic JC, Mehran R, Lip GY. Coronary stent implantation in patients committed to long-term oral anticoagulation therapy: successfully navigating the treatment options. Chest. 2011 May;139(5):981-7. doi: 10.1378/chest.10-2719. PubMed PMID: 21540213. 316: Rasmussen LH, Larsen TB, Due KM, Tjønneland A, Overvad K, Lip GY. Impact of vascular disease in predicting stroke and death in patients with atrial fibrillation: the Danish Diet, Cancer and Health cohort study. J Thromb Haemost. 2011 Jul;9(7):1301-7. doi: 10.1111/j.1538-7836.2011.04308.x. PubMed PMID: 21535388. 317: Blomstrom Lundqvist C, Lip GY, Kirchhof P. What are the costs of atrial fibrillation? Europace. 2011 May;13 Suppl 2:ii9-12. doi: 10.1093/europace/eur087. PubMed PMID: 21518753. 318: Lip GY, Andreotti F, Fauchier L, Huber K, Hylek E, Knight E, Lane DA, Levi M, Marin F, Palareti G, Kirchhof P; Document reviewers:, Collet JP, Rubboli A, Poli D, Camm J. Bleeding risk assessment and management in atrial fibrillation patients: a position document from the European Heart Rhythm Association, endorsed by the European Society of Cardiology Working Group on Thrombosis. Europace. 2011 May;13(5):723-46. doi: 10.1093/europace/eur126. PubMed PMID: 45 21515596. 319: Jowett S, Bryan S, Mant J, Fletcher K, Roalfe A, Fitzmaurice D, Lip GY, Hobbs FD. Cost effectiveness of warfarin versus aspirin in patients older than 75 years with atrial fibrillation. Stroke. 2011 Jun;42(6):1717-21. doi: 10.1161/STROKEAHA.110.600767. Epub 2011 Apr 21. PubMed PMID: 21512184. 320: Poli D, Testa S, Antonucci E, Grifoni E, Paoletti O, Lip GY. Bleeding and stroke risk in a real-world prospective primary prevention cohort of patients with atrial fibrillation. Chest. 2011 Oct;140(4):918-24. doi: 10.1378/chest.10-3024. Epub 2011 Apr 21. PubMed PMID: 21511826. 321: Blann AD, Ramcharan KS, Stonelake PS, Luesley D, Lip GY. The angiome: a new concept in cancer biology. J Clin Pathol. 2011 Jul;64(7):637-43. doi: 10.1136/jcp.2011.088948. Epub 2011 Apr 20. Review. PubMed PMID: 21508416. 322: Orenes-Piñero E, Hernández-Romero D, Jover E, Valdés M, Lip GY, Marín F. Impact of polymorphisms in the renin-angiotensin-aldosterone system on hypertrophic cardiomyopathy. J Renin Angiotensin Aldosterone Syst. 2011 Dec;12(4):521-30. doi: 10.1177/1470320311405247. Epub 2011 Apr 20. Review. PubMed PMID: 21507890. 323: Roldán V, Marín F, Muiña B, Torregrosa JM, Hernández-Romero D, Valdés M, Vicente V, Lip GY. Plasma von Willebrand factor levels are an independent risk factor for adverse events including mortality and major bleeding in anticoagulated atrial fibrillation patients. J Am Coll Cardiol. 2011 Jun 21;57(25):2496-504. doi: 10.1016/j.jacc.2010.12.033. Epub 2011 Apr 14. PubMed PMID: 21497043. 324: Boriani G, Botto GL, Padeletti L, Santini M, Capucci A, Gulizia M, Ricci R, Biffi M, De Santo T, Corbucci G, Lip GY; Italian AT-500 Registry Investigators. Improving stroke risk stratification using the CHADS2 and CHA2DS2-VASc risk scores in patients with paroxysmal atrial fibrillation by continuous arrhythmia burden monitoring. Stroke. 2011 Jun;42(6):1768-70. doi: 10.1161/STROKEAHA.110.609297. Epub 2011 Apr 14. PubMed PMID: 21493904. 325: Heitmar R, Cubbidge RP, Lip GY, Gherghel D, Blann AD. Altered blood vessel responses in the eye and finger in coronary artery disease. Invest Ophthalmol Vis Sci. 2011 Aug 3;52(9):6199-205. doi: 10.1167/iovs.10-6628. PubMed PMID: 21474768. 46 326: Jaumdally RJ, Lip GY, Varma C, Blann AD. Impact of high-dose atorvastatin on endothelial, platelet, and angiogenic indices: effect of ethnicity, cardiovascular disease, and diabetes. Angiology. 2011 Oct;62(7):571-8. doi: 10.1177/0003319711401904. Epub 2011 Apr 5. PubMed PMID: 21467120. 327: Lip GY, Halperin JL, Tse HF. The 2010 European Society of Cardiology Guidelines on the management of atrial fibrillation: an evolution or revolution? Chest. 2011 Apr;139(4):738-41. doi: 10.1378/chest.10-2763. PubMed PMID: 21467053. 328: Potpara TS, Vasiljevic ZM, Vujisic-Tesic BD, Marinkovic JM, Polovina MM, Stepanovic JM, Stankovic GR, Ostojic MC, Lip GY. Mitral annular calcification predicts cardiovascular morbidity and mortality in middle-aged patients with atrial fibrillation: the Belgrade Atrial Fibrillation Study. Chest. 2011 Oct;140(4):902-10. doi: 10.1378/chest.10-2963. Epub 2011 Mar 24. PubMed PMID: 21436252. 329: Gorin L, Fauchier L, Nonin E, Charbonnier B, Babuty D, Lip GY. Prognosis and guideline-adherent antithrombotic treatment in patients with atrial fibrillation and atrial flutter: implications of undertreatment and overtreatment in real-life clinical practice; the Loire Valley Atrial Fibrillation Project. Chest. 2011 Oct;140(4):911-7. doi: 10.1378/chest.10-2436. Epub 2011 Mar 24. PubMed PMID: 21436246. 330: Lane DA, Kamphuisen PW, Minini P, Büller HR, Lip GY. Bleeding risk in patients with atrial fibrillation: the AMADEUS study. Chest. 2011 Jul;140(1):146-55. doi: 10.1378/chest.10-3270. Epub 2011 Mar 17. PubMed PMID: 21415134. 331: Marinigh R, Lane DA, Lip GY. Severe renal impairment and stroke prevention in atrial fibrillation: implications for thromboprophylaxis and bleeding risk. J Am Coll Cardiol. 2011 Mar 22;57(12):1339-48. doi: 10.1016/j.jacc.2010.12.013. Review. PubMed PMID: 21414530. 332: ACTIVE I Investigators, Yusuf S, Healey JS, Pogue J, Chrolavicius S, Flather M, Hart RG, Hohnloser SH, Joyner CD, Pfeffer MA, Connolly SJ. Irbesartan in patients with atrial fibrillation. N Engl J Med. 2011 Mar 10;364(10):928-38. doi: 10.1056/NEJMoa1008816. PubMed PMID: 21388310. 47 333: Shantsila E, Wrigley B, Tapp L, Apostolakis S, Montoro-Garcia S, Drayson MT, Lip GY. Immunophenotypic characterization of human monocyte subsets: possible implications for cardiovascular disease pathophysiology. J Thromb Haemost. 2011 May;9(5):1056-66. doi: 10.1111/j.1538-7836.2011.04244.x. PubMed PMID: 21342432. 334: Montoro-García S, Lip PL, Chan CC, Lip GY. Soluble vascular endothelial growth factor receptor (VEGFR)-2 in macular oedema--a mechanism for regulating angiogenesis? Br J Ophthalmol. 2011 Jun;95(6):757-8. doi: 10.1136/bjo.2010.198002. Epub 2011 Feb 16. PubMed PMID: 21325396. 335: Lip GY, Durrani OM, Roldan V, Lip PL, Marin F, Reuser TQ. Peri-operative management of ophthalmic patients taking antithrombotic therapy. Int J Clin Pract. 2011 Mar;65(3):361-71. doi: 10.1111/j.1742-1241.2010.02538.x. Review. PubMed PMID: 21314873. 336: Connolly SJ, Eikelboom J, Joyner C, Diener HC, Hart R, Golitsyn S, Flaker G, Avezum A, Hohnloser SH, Diaz R, Talajic M, Zhu J, Pais P, Budaj A, Parkhomenko A, Jansky P, Commerford P, Tan RS, Sim KH, Lewis BS, Van Mieghem W, Lip GY, Kim JH, Lanas-Zanetti F, Gonzalez-Hermosillo A, Dans AL, Munawar M, O'Donnell M, Lawrence J, Lewis G, Afzal R, Yusuf S; AVERROES Steering Committee and Investigators. Apixaban in patients with atrial fibrillation. N Engl J Med. 2011 Mar 3;364(9):806-17. doi: 10.1056/NEJMoa1007432. Epub 2011 Feb 10. PubMed PMID: 21309657. 337: Disney BR, Watson RD, Blann AD, Lip GY, Anderson MR. Review article: proton pump inhibitors with clopidogrel--evidence for and against a clinically-important interaction. Aliment Pharmacol Ther. 2011 Apr;33(7):758-67. doi: 10.1111/j.1365-2036.2011.04585.x. Epub 2011 Feb 8. Review. PubMed PMID: 21303400. 338: Shantsila E, Lip GY. The risk of thromboembolism in heart failure: does it merit anticoagulation therapy? Am J Cardiol. 2011 Feb 15;107(4):558-60. doi: 10.1016/j.amjcard.2010.10.029. PubMed PMID: 21295173. 339: Tapp LD, Lip GY, Lane DA. Optimal antithrombotic therapy in patients receiving long-term oral anticoagulation requiring percutaneous coronary intervention: "triple therapy" or "triple threat". Chest. 2011 Feb;139(2):240-2. doi: 10.1378/chest.10-1102. PubMed PMID: 21285051. 48 340: Olesen JB, Lip GY, Hansen ML, Hansen PR, Tolstrup JS, Lindhardsen J, Selmer C, Ahlehoff O, Olsen AM, Gislason GH, Torp-Pedersen C. Validation of risk stratification schemes for predicting stroke and thromboembolism in patients with atrial fibrillation: nationwide cohort study. BMJ. 2011 Jan 31;342:d124. doi: 10.1136/bmj.d124. PubMed PMID: 21282258; PubMed Central PMCID: PMC3031123. 341: Ghattas A, Shantsila E, Lip GY. Antithrombotic therapy after percutaneous coronary intervention in anticoagulated patients: a fine balance between thrombosis and bleeding. Ther Adv Cardiovasc Dis. 2011 Feb;5(1):5-9. doi: 10.1177/1753944710397225. PubMed PMID: 21282200. 342: Shantsila E, Lip GY. Monocytes: possible mediators of benefits and harms from physical activity? Thromb Haemost. 2011 Mar;105(3):387-9. doi: 10.1160/TH11-01-0009. Epub 2011 Jan 25. PubMed PMID: 21264444. 343: Blann AD, Balakrishnan B, Ryan P, Lip GY. Increased levels of plasma haemoxygenase-1 in prostate cancer. Prostate Cancer Prostatic Dis. 2011 Jun;14(2):114-7. doi: 10.1038/pcan.2010.56. Epub 2011 Jan 25. PubMed PMID: 21263452. 344: Shantsila A, Dwivedi G, Shantsila E, Butt M, Beevers DG, Lip GY. Persistent macrovascular and microvascular dysfunction in patients with malignant hypertension. Hypertension. 2011 Mar;57(3):490-6. doi: 10.1161/HYPERTENSIONAHA.110.166314. Epub 2011 Jan 24. PubMed PMID: 21263115. 345: Lip GY, Weber C. Clinical and basic science articles from Thrombosis and Haemostasis. Thromb Haemost. 2011 Jan;105(1):202-5. PubMed PMID: 21249716. 346: Kuzniatsova N, Lip GY. Combined antiplatelet therapy and oral anticoagulation: is a balance between thromboembolism and bleeding possible? Int J Cardiol. 2011 Apr 1;148(1):1-3. doi: 10.1016/j.ijcard.2010.12.098. Epub 2011 Jan 17. PubMed PMID: 21247646. 347: Pamukcu B, Lip GY, Snezhitskiy V, Shantsila E. The CD40-CD40L system in cardiovascular disease. Ann Med. 2011 Aug;43(5):331-40. doi: 10.3109/07853890.2010.546362. Epub 2011 Jan 18. Review. PubMed PMID: 21244217. 348: Ghattas A, Lip PL, Lip GY. Renin-angiotensin blockade in diabetic 49 retinopathy. Int J Clin Pract. 2011 Feb;65(2):113-6. doi: 10.1111/j.1742-1241.2010.02592.x. PubMed PMID: 21235693. 349: Bennett PC, Gill PS, Silverman S, Blann AD, Chackathayil J, Lip GY. Hemostatic cardiovascular risk factors, common carotid-intima medial thickness and peripheral arterial disease in South Asians and African Caribbeans: a substudy to the Ethnic-Echocardiographic Heart of England Screening (E-ECHOES) study. J Thromb Haemost. 2011 Apr;9(4):645-52. doi: 10.1111/j.1538-7836.2011.04190.x. PubMed PMID: 21232010. 350: Ahrens I, Lip GY, Peter K. What do the RE-LY, AVERROES and ROCKET-AF trials tell us for stroke prevention in atrial fibrillation? Thromb Haemost. 2011 Apr;105(4):574-8. doi: 10.1160/TH10-12-0808. Epub 2011 Jan 12. PubMed PMID: 21225102. 351: Karthikeyan VJ, Blann AD, Baghdadi S, Lane DA, Gareth Beevers D, Lip GY. Endothelial dysfunction in hypertension in pregnancy: associations between circulating endothelial cells, circulating progenitor cells and plasma von Willebrand factor. Clin Res Cardiol. 2011 Jun;100(6):531-7. doi: 10.1007/s00392-010-0277-9. Epub 2011 Jan 9. PubMed PMID: 21221608. 352: Potpara TS, Lip GY. Lone atrial fibrillation: what is known and what is to come. Int J Clin Pract. 2011 Apr;65(4):446-57. doi: 10.1111/j.1742-1241.2010.02618.x. Epub 2011 Jan 11. Review. PubMed PMID: 21219558. 353: Tay KH, Lip GY, Lane DA. Can we IMPROVE bleeding risk assessment for acutely ill, hospitalized medical patients? Chest. 2011 Jan;139(1):10-3. doi: 10.1378/chest.10-1127. PubMed PMID: 21208874. 354: de Peuter OR, Lip GY, Souverein PC, Klungel OH, de Boer A, Büller HR, Kamphuisen PW. Time-trends in treatment and cardiovascular events in patients with heart failure: a pharmacosurveillance study. Eur J Heart Fail. 2011 May;13(5):489-95. doi: 10.1093/eurjhf/hfq228. Epub 2010 Dec 29. PubMed PMID: 21193438. 355: Lip GY, Rasmussen LH, Olsson SB, Zetterstrand S, Stahre C, Bylock A, Aunes-Jansson M, Eriksson U, Wåhlander K; Steering Committee. Oral direct thrombin inhibitor AZD0837 for the prevention of stroke and systemic embolism in 50 patients with non-valvular atrial fibrillation: a Phase II study of AZD0837 in patients who are appropriate for but unable or unwilling to take vitamin K antagonist therapy. Thromb Res. 2011 Feb;127(2):91-9. doi: 10.1016/j.thromres.2010.11.012. Epub 2010 Dec 18. PubMed PMID: 21172721. 356: Ramcharan KS, Lip GY, Stonelake PS, Blann AD. The endotheliome: a new concept in vascular biology. Thromb Res. 2011 Jul;128(1):1-7. doi: 10.1016/j.thromres.2010.11.019. Epub 2010 Dec 18. Review. PubMed PMID: 21168189. 357: Mohan JS, Lip GY, Blann AD, Bareford D, Marshall JM. Endothelium-dependent and endothelium-independent vasodilatation of the cutaneous circulation in sickle cell disease. Eur J Clin Invest. 2011 May;41(5):546-51. doi: 10.1111/j.1365-2362.2010.02444.x. Epub 2010 Dec 15. PubMed PMID: 21158851. 358: Velu S, Lip GY. What is the role of the cardiologist in future management of stroke prevention in atrial fibrillation? Adv Ther. 2011 Jan;28(1):1-12. doi: 10.1007/s12325-010-0091-9. Epub 2010 Dec 6. Review. PubMed PMID: 21153001. 359: Ezekowitz MD, Wallentin L, Connolly SJ, Parekh A, Chernick MR, Pogue J, Aikens TH, Yang S, Reilly PA, Lip GY, Yusuf S; RE-LY Steering Committee and Investigators. Dabigatran and warfarin in vitamin K antagonist-naive and -experienced cohorts with atrial fibrillation. Circulation. 2010 Nov 30;122(22):2246-53. doi: 10.1161/CIRCULATIONAHA.110.973735. PubMed PMID: 21147728. 360: Schirmer SH, Baumhäkel M, Neuberger HR, Hohnloser SH, van Gelder IC, Lip GY, Böhm M. Novel anticoagulants for stroke prevention in atrial fibrillation: current clinical evidence and future developments. J Am Coll Cardiol. 2010 Dec 14;56(25):2067-76. doi: 10.1016/j.jacc.2010.09.017. Review. PubMed PMID: 21144965. 361: Lip GY. Chronic renal disease and stroke in atrial fibrillation: balancing the prevention of thromboembolism and bleeding risk. Europace. 2011 Feb;13(2):145-8. doi: 10.1093/europace/euq427. Epub 2010 Dec 7. PubMed PMID: 21138929. 362: Pamukcu B, Lip GY. Dronedarone as a new treatment option for atrial fibrillation patients: pharmacokinetics, pharmacodynamics and clinical practice. Expert Opin Pharmacother. 2011 Jan;12(1):131-40. doi: 51 10.1517/14656566.2011.540800. Epub 2010 Dec 2. Review. PubMed PMID: 21126199. 363: Karthikeyan VJ, Ferner RE, Baghdadi S, Lane DA, Lip GY, Beevers DG. Are angiotensin-converting enzyme inhibitors and angiotensin receptor blockers safe in pregnancy: a report of ninety-one pregnancies. J Hypertens. 2011 Feb;29(2):396-9. doi: 10.1097/HJH.0b013e328341885d. PubMed PMID: 21119533. 364: Lip GY, Frison L, Halperin JL, Lane DA. Comparative validation of a novel risk score for predicting bleeding risk in anticoagulated patients with atrial fibrillation: the HAS-BLED (Hypertension, Abnormal Renal/Liver Function, Stroke, Bleeding History or Predisposition, Labile INR, Elderly, Drugs/Alcohol Concomitantly) score. J Am Coll Cardiol. 2011 Jan 11;57(2):173-80. doi: 10.1016/j.jacc.2010.09.024. Epub 2010 Nov 24. PubMed PMID: 21111555. 365: Pamukcu B, Lane DA, Lip GY. The assessment of stroke and bleeding risk in atrial fibrillation: where are we now? Expert Rev Cardiovasc Ther. 2010 Dec;8(12):1703-10. doi: 10.1586/erc.10.153. Review. PubMed PMID: 21108552. 366: Kuzniatsova N, Lip GY. New concepts and approaches to stroke prevention in the new European Society of Cardiology guidelines for the management of atrial fibrillation. Expert Rev Cardiovasc Ther. 2010 Dec;8(12):1643-7. doi: 10.1586/erc.10.150. PubMed PMID: 21108546. 367: Velu S, Lip GY. Recent progress in antithrombotic therapy for atrial fibrillation. J Atheroscler Thromb. 2011;18(4):257-73. Epub 2010 Nov 13. Review. PubMed PMID: 21088368. 368: Lane DA, Lip GY. Dabigatran in atrial fibrillation: balancing secondary stroke prevention against bleeding risk. Lancet Neurol. 2010 Dec;9(12):1140-2. doi: 10.1016/S1474-4422(10)70275-1. Epub 2010 Nov 6. PubMed PMID: 21059485. 369: Pamukcu B, Lip GY. Dronedarone or amiodarone for rhythm control for atrial fibrillation: implications from the DIONYSOS study. Expert Opin Pharmacother. 2010 Dec;11(17):2775-8. doi: 10.1517/14656566.2010.517196. PubMed PMID: 21050033. 370: Van Staa TP, Setakis E, Di Tanna GL, Lane DA, Lip GY. A comparison of risk stratification schemes for stroke in 79,884 atrial fibrillation patients in general practice. J Thromb Haemost. 2011 Jan;9(1):39-48. doi: 52 10.1111/j.1538-7836.2010.04085.x. PubMed PMID: 21029359. 371: Montoro-García S, Marín F, Lip GY. Thrombogenesis in lone atrial fibrillation: a role for soluble P-selectin? Europace. 2011 Jan;13(1):3-4. doi: 10.1093/europace/euq376. Epub 2010 Oct 25. PubMed PMID: 20974759. 372: Roskell NS, Lip GY, Noack H, Clemens A, Plumb JM. Treatments for stroke prevention in atrial fibrillation: a network meta-analysis and indirect comparisons versus dabigatran etexilate. Thromb Haemost. 2010 Dec;104(6):1106-15. doi: 10.1160/TH10-10-0642. Epub 2010 Oct 21. PubMed PMID: 20967400. 373: Lip GY, Frison L, Halperin JL, Lane DA. Identifying patients at high risk for stroke despite anticoagulation: a comparison of contemporary stroke risk stratification schemes in an anticoagulated atrial fibrillation cohort. Stroke. 2010 Dec;41(12):2731-8. doi: 10.1161/STROKEAHA.110.590257. Epub 2010 Oct 21. PubMed PMID: 20966417. 374: Bennett PC, Gill PS, Silverman S, Blann AD, Lip GY. Ethnic differences in common carotid intima-media thickness, and the relationship to cardiovascular risk factors and peripheral arterial disease: the Ethnic-Echocardiographic Heart of England Screening Study. QJM. 2011 Mar;104(3):245-54. doi: 10.1093/qjmed/hcq187. Epub 2010 Oct 18. PubMed PMID: 20956456. 375: Pamukcu B, Lip GY. Insights from the new European Society of Cardiology guidelines for the medical management of atrial fibrillation. Int J Clin Pract. 2010 Nov;64(12):1587-90. doi: 10.1111/j.1742-1241.2010.02522.x. PubMed PMID: 20946264. 376: Wrigley BJ, Shantsila E, Lip GY. Percutaneous coronary intervention in anticoagulated patients and balancing the risk of stroke and bleeding: to interrupt or not to interrupt? Chest. 2010 Oct;138(4):771-4. doi: 10.1378/chest.10-0789. PubMed PMID: 20923795. 377: Lip GY. Implications of the CHA(2)DS(2)-VASc and HAS-BLED Scores for thromboprophylaxis in atrial fibrillation. Am J Med. 2011 Feb;124(2):111-4. doi: 10.1016/j.amjmed.2010.05.007. Epub 2010 Sep 29. PubMed PMID: 20887966. 378: Airaksinen KE, Schlitt A, Rubboli A, Karjalainen P, Lip GY. How to manage 53 antithrombotic treatment during percutaneous coronary interventions in patients receiving long-term oral anticoagulation: to "bridge" or not to "bridge"? EuroIntervention. 2010 Sep;6(4):520-6. doi: 10.4244/EIJ30V6I4A86. Review. PubMed PMID: 20884441. 379: European Heart Rhythm Association; European Association for Cardio-Thoracic Surgery, Camm AJ, Kirchhof P, Lip GY, Schotten U, Savelieva I, Ernst S, Van Gelder IC, Al-Attar N, Hindricks G, Prendergast B, Heidbuchel H, Alfieri O, Angelini A, Atar D, Colonna P, De Caterina R, De Sutter J, Goette A, Gorenek B, Heldal M, Hohloser SH, Kolh P, Le Heuzey JY, Ponikowski P, Rutten FH; ESC Committee for Practice Guidelines. Guidelines for the management of atrial fibrillation: the Task Force for the Management of Atrial Fibrillation of the European Society of Cardiology (ESC). Europace. 2010 Oct;12(10):1360-420. doi: 10.1093/europace/euq350. Erratum in: Europace. 2011 Jul;13(7):1058. Dosage error in article text. PubMed PMID: 20876603. 380: Montoro-García S, Shantsila E, Lip GY. Platelet reactivity in prolonged stress disorders--a link with cardiovascular disease? Psychoneuroendocrinology. 2011 Feb;36(2):159-60. doi: 10.1016/j.psyneuen.2010.08.010. Epub 2010 Sep 28. PubMed PMID: 20875929. 381: Ruiz-Nodar JM, Marín F, Manzano-Fernández S, Valencia-Martín J, Hurtado JA, Roldán V, Pineda J, Pinar E, Sogorb F, Valdés M, Lip GY. An evaluation of the CHADS₂ stroke risk score in patients with atrial fibrillation who undergo percutaneous coronary revascularization. Chest. 2011 Jun;139(6):1402-9. doi: 10.1378/chest.10-1408. Epub 2010 Sep 23. PubMed PMID: 20864616. 382: Butt M, Dwivedi G, Blann A, Khair O, Lip GY. Endothelial dysfunction: methods of assessment & implications for cardiovascular diseases. Curr Pharm Des. 2010;16(31):3442-54. Review. PubMed PMID: 20858188. 383: Potpara TS, Lip GY. Current therapeutic strategies and future perspectives for the prevention of arterial thromboembolism: focus on atrial fibrillation. Curr Pharm Des. 2010;16(31):3455-71. Review. PubMed PMID: 20858180. 384: Idriss NK, Lip GY, Balakrishnan B, Jaumdally R, Boos CJ, Blann AD. Plasma haemoxygenase-1 in coronary artery disease. A comparison with angiogenin, matrix metalloproteinase-9, tissue inhibitor of metalloproteinase-1 and vascular endothelial growth factor. Thromb Haemost. 2010 Nov;104(5):1029-37. doi: 10.1160/TH09-11-0802. Epub 2010 Sep 13. PubMed PMID: 20838751. 54 385: Pamukcu B, Shantsila E, Lip GY. Soluble fms-like tyrosine kinase-1 – a novel marker for atherosclerotic progression? –. Circ J. 2010 Oct;74(10):2064-5. Epub 2010 Sep 11. PubMed PMID: 20838011. 386: Khoo CW, Krishnamoorthy S, Lim HS, Lip GY. Assessment of left atrial volume: a focus on echocardiographic methods and clinical implications. Clin Res Cardiol. 2011 Feb;100(2):97-105. doi: 10.1007/s00392-010-0222-y. Epub 2010 Sep 7. Review. PubMed PMID: 20821219. 387: Marinigh R, Lip GY, Fiotti N, Giansante C, Lane DA. Age as a risk factor for stroke in atrial fibrillation patients implications for thromboprophylaxis: Implications for thromboprophylaxis. J Am Coll Cardiol. 2010 Sep 7;56(11):827-37. doi: 10.1016/j.jacc.2010.05.028. Review. PubMed PMID: 20813280. 388: Kuzniatsova N, Lip GY. How do we get better at identifying patients with atrial fibrillation who are at 'truly low risk' or 'truly high risk' of stroke? J Neurol Sci. 2010 Nov 15;298(1-2):21-2. doi: 10.1016/j.jns.2010.08.015. Epub 2010 Sep 1. Review. PubMed PMID: 20810129. 389: European Heart Rhythm Association; European Association for Cardio-Thoracic Surgery, Camm AJ, Kirchhof P, Lip GY, Schotten U, Savelieva I, Ernst S, Van Gelder IC, Al-Attar N, Hindricks G, Prendergast B, Heidbuchel H, Alfieri O, Angelini A, Atar D, Colonna P, De Caterina R, De Sutter J, Goette A, Gorenek B, Heldal M, Hohloser SH, Kolh P, Le Heuzey JY, Ponikowski P, Rutten FH. Guidelines for the management of atrial fibrillation: the Task Force for the Management of Atrial Fibrillation of the European Society of Cardiology (ESC). Eur Heart J. 2010 Oct;31(19):2369-429. doi: 10.1093/eurheartj/ehq278. Epub 2010 Aug 29. Erratum in: Eur Heart J. 2011 May;32(9):1172. PubMed PMID: 20802247. 390: Lane DA, Lip GY. Quality of anticoagulation control in atrial fibrillation. Lancet. 2010 Sep 18;376(9745):935-7. doi: 10.1016/S0140-6736(10)61305-0. PubMed PMID: 20801499. 391: Marinigh R, Lip GY, Lane DA. Stroke prevention in atrial fibrillation patients. Expert Opin Pharmacother. 2010 Oct;11(14):2331-50. doi: 10.1517/14656566.2010.498819. Review. PubMed PMID: 20718589. 55 392: Marín F, Lip GY. Rhythm control agents and adverse events in patients with atrial fibrillation. Int J Clin Pract. 2010 Sep;64(10):1329-31. doi: 10.1111/j.1742-1241.2010.02473.x. PubMed PMID: 20716137. 393: Shantsila A, Lip GY. Statins and prophylaxis of venous thrombosis - a further link between arterial and venous thrombosis. Int J Clin Pract. 2010 Sep;64(10):1326-8. doi: 10.1111/j.1742-1241.2010.02461.x. PubMed PMID: 20716136. 394: Shantsila E, Kamphuisen PW, Lip GY. Circulating microparticles in cardiovascular disease: implications for atherogenesis and atherothrombosis. J Thromb Haemost. 2010 Nov;8(11):2358-68. doi: 10.1111/j.1538-7836.2010.04007.x. Review. PubMed PMID: 20695980. 395: Wrigley BJ, Tapp LD, Shantsila E, Lip GY. Antithrombotic therapy in anticoagulated patients with atrial fibrillation presenting with acute coronary syndromes and/or undergoing percutaneous coronary intervention/stenting. Pol Arch Med Wewn. 2010 Jul;120(7-8):290-3. Review. Erratum in: Pol Arch Med Wewn. 2010 Sep;120(9):374. PubMed PMID: 20693960. 396: Lane DA, Lip GY. Atrial fibrillation and mortality: the impact of antithrombotic therapy. Eur Heart J. 2010 Sep;31(17):2075-6. doi: 10.1093/eurheartj/ehp486. Epub 2010 Aug 4. PubMed PMID: 20685675. 397: López-Cuenca A, Marín F, Roldán V, González-Conejero R, Hernández-Romero D, Valdés M, Lip GY. Genetic polymorphisms and atrial fibrillation: Insights into the prothrombotic state and thromboembolic risk. Ann Med. 2010 Dec;42(8):562-75. doi: 10.3109/07853890.2010.507601. Epub 2010 Aug 4. Review. PubMed PMID: 20681943. 398: Khoo CW, Lim HS, Lip GY. Dronedarone: NICE enough? Expert Rev Cardiovasc Ther. 2010 Aug;8(8):1049-51. doi: 10.1586/erc.10.83. PubMed PMID: 20670181. 399: Kuzniatsova N, Shantsila E, Lip GY. Atrial fibrillation: Blockade of the renin-angiotensin system in atrial fibrillation. Nat Rev Cardiol. 2010 Aug;7(8):428-30. doi: 10.1038/nrcardio.2010.103. PubMed PMID: 20657612. 400: Lip GY, Lane DA. Does warfarin for stroke thromboprophylaxis protect against MI in atrial fibrillation patients? Am J Med. 2010 Sep;123(9):785-9. doi: 56 10.1016/j.amjmed.2010.01.031. Epub 2010 Jul 23. Review. PubMed PMID: 20655037. 401: Poli D, Lip GY, Antonucci E, Grifoni E, Lane D. Stroke risk stratification in a "real-world" elderly anticoagulated atrial fibrillation population. J Cardiovasc Electrophysiol. 2011 Jan;22(1):25-30. doi: 10.1111/j.1540-8167.2010.01858.x. PubMed PMID: 20653814. 402: Kowalczyk M, Banach M, Lip GY, Kozłowski D, Mikhailidis DP, Rysz J. Levosimendan - a calcium sensitising agent with potential anti-arrhythmic properties. Int J Clin Pract. 2010 Jul;64(8):1148-54. doi: 10.1111/j.1742-1241.2010.02396.x. Review. PubMed PMID: 20642713. 403: Shantsila A, Shantsila E, Lip GY. Malignant hypertension: a rare problem or is it underdiagnosed? Curr Vasc Pharmacol. 2010 Nov;8(6):775-9. Review. PubMed PMID: 20626341. 404: Ogilvie IM, Newton N, Welner SA, Cowell W, Lip GY. Underuse of oral anticoagulants in atrial fibrillation: a systematic review. Am J Med. 2010 Jul;123(7):638-645.e4. doi: 10.1016/j.amjmed.2009.11.025. Review. PubMed PMID: 20609686. 405: Ho LY, Siu CW, Yue WS, Lau CP, Lip GY, Tse HF. Safety and efficacy of oral anticoagulation therapy in Chinese patients with concomitant atrial fibrillation and hypertension. J Hum Hypertens. 2011 May;25(5):304-10. doi: 10.1038/jhh.2010.57. Epub 2010 Jul 1. PubMed PMID: 20596062. 406: Hernández-Romero D, Marín F, Lee KW, Roldán V, Caturla J, Corral J, Valdés M, Lip GY, Vicente V, González-Conejero R. Synergism between factor XII -4C>T and factor XIII Val34Leu polymorphisms in fibrinolytic therapy in acute myocardial infarction. Thromb Haemost. 2010 Sep;104(3):650-2. doi: 10.1160/TH10-01-0022. Epub 2010 Jun 29. PubMed PMID: 20589311. 407: Wrigley BJ, Lip GY, Shantsila E. Novel oral anticoagulants: the potential relegation of vitamin K antagonists in clinical practice. Int J Clin Pract. 2010 Jun;64(7):835-8. doi: 10.1111/j.1742-1241.2010.02351.x. PubMed PMID: 20584215. 408: Jaipersad AS, Silverman SH, Lip GY. Peripheral artery disease: appreciating the asymptomatic - yet lethal - epidemic. Int J Clin Pract. 2010 Jun;64(7):832-5. 57 doi: 10.1111/j.1742-1241.2010.02393.x. PubMed PMID: 20584214. 409: Bennett PC, Lip GY, Silverman S, Blann AD, Gill PS. The contribution of cardiovascular risk factors to peripheral arterial disease in South Asians and Blacks: a sub-study to the Ethnic-Echocardiographic Heart of England Screening (E-ECHOES) study. QJM. 2010 Sep;103(9):661-9. doi: 10.1093/qjmed/hcq102. Epub 2010 Jun 24. PubMed PMID: 20576717. 410: Lip GY, Halperin JL. Improving stroke risk stratification in atrial fibrillation. Am J Med. 2010 Jun;123(6):484-8. doi: 10.1016/j.amjmed.2009.12.013. Review. PubMed PMID: 20569748. 411: Pamukcu B, Lip GY, Devitt A, Griffiths H, Shantsila E. The role of monocytes in atherosclerotic coronary artery disease. Ann Med. 2010 Sep;42(6):394-403. doi: 10.3109/07853890.2010.497767. Review. PubMed PMID: 20568979. 412: Patel JV, Tracey I, Hughes EA, Lip GY. Omega-3 polyunsaturated acids and cardiovascular disease: notable ethnic differences or unfulfilled promise? J Thromb Haemost. 2010 Oct;8(10):2095-104. doi: 10.1111/j.1538-7836.2010.03956.x. Review. PubMed PMID: 20561183. 413: Apostolakis S, Lip GY, Lane DA, Shantsila E. The quest for new anticoagulants: from clinical development to clinical practice. Cardiovasc Ther. 2011 Dec;29(6):e12-22. doi: 10.1111/j.1755-5922.2010.00160.x. Epub 2010 Jun 14. Review. PubMed PMID: 20553291. 414: Ahrens I, Lip GY, Peter K. New oral anticoagulant drugs in cardiovascular disease. Thromb Haemost. 2010 Jul;104(1):49-60. doi: 10.1160/TH09-05-0327. Epub 2010 Jun 10. Review. PubMed PMID: 20539909. 415: Bjerre M, Kistorp C, Hansen TK, Faber J, Lip GY, Hildebrandt P, Flyvbjerg A. Complement activation, endothelial dysfunction, insulin resistance and chronic heart failure. Scand Cardiovasc J. 2010 Oct;44(5):260-6. doi: 10.3109/14017431.2010.484506. Epub 2010 Jun 7. PubMed PMID: 20524927. 416: Watson T, Shantsila E, Blann A, Lip GY. Circulating progenitor cells in patients with atrial fibrillation and their relation with serum markers of inflammation and angiogenesis. Thromb Haemost. 2010 Aug;104(2):327-34. doi: 58 10.1160/TH10-01-0024. Epub 2010 May 27. PubMed PMID: 20508899. 417: Pamukcu B, Lip GY, Lane DA. Simplifying stroke risk stratification in atrial fibrillation patients: implications of the CHA2DS2-VASc risk stratification scores. Age Ageing. 2010 Sep;39(5):533-5. doi: 10.1093/ageing/afq059. Epub 2010 May 26. Erratum in: Age Ageing. 2011 Jan;40(1):141. PubMed PMID: 20507847. 418: Smith DE, Xuereb CB, Pattison HM, Lip GY, Lane DA. TRial of an Educational intervention on patients' knowledge of Atrial fibrillation and anticoagulant therapy, INR control, and outcome of Treatment with warfarin (TREAT). BMC Cardiovasc Disord. 2010 May 20;10:21. doi: 10.1186/1471-2261-10-21. PubMed PMID: 20487528; PubMed Central PMCID: PMC2887377. 419: Kaireviciute D, Blann AD, Balakrishnan B, Lane DA, Patel JV, Uzdavinys G, Norkunas G, Kalinauskas G, Sirvydis V, Aidietis A, Lip GY. Characterisation and validity of inflammatory biomarkers in the prediction of post-operative atrial fibrillation in coronary artery disease patients. Thromb Haemost. 2010 Jul;104(1):122-7. doi: 10.1160/TH09-12-0837. Epub 2010 May 10. PubMed PMID: 20458440. 420: Lip GY, Huber K, Andreotti F, Arnesen H, Airaksinen JK, Cuisset T, Kirchhof P, Marín F; Consensus Document of European Society of Cardiology Working Group on Thrombosis. Antithrombotic management of atrial fibrillation patients presenting with acute coronary syndrome and/or undergoing coronary stenting: executive summary--a Consensus Document of the European Society of Cardiology Working Group on Thrombosis, endorsed by the European Heart Rhythm Association (EHRA) and the European Association of Percutaneous Cardiovascular Interventions (EAPCI). Eur Heart J. 2010 Jun;31(11):1311-8. doi: 10.1093/eurheartj/ehq117. Epub 2010 May 6. PubMed PMID: 20447945. 421: Heitmar R, Blann AD, Cubbidge RP, Lip GY, Gherghel D. Continuous retinal vessel diameter measurements: the future in retinal vessel assessment? Invest Ophthalmol Vis Sci. 2010 Nov;51(11):5833-9. doi: 10.1167/iovs.09-5136. Epub 2010 Apr 30. PubMed PMID: 20435593. 422: Shantsila E, Devitt A, Lip GY. Circulating monocytes and atherogenesis: from animal experiments to human studies. Thromb Haemost. 2010 Aug;104(2):191-3. doi: 10.1160/TH10-03-0176. Epub 2010 Apr 29. PubMed PMID: 20431844. 59 423: Aliot E, Breithardt G, Brugada J, Camm J, Lip GY, Vardas PE, Wagner M; Atrial Fibrillation AWareness And Risk Education group; Atrial Fibrillation Association; European Heart Rhythm Association; Stroke Alliance for Europe; World Heart Federation. An international survey of physician and patient understanding, perception, and attitudes to atrial fibrillation and its contribution to cardiovascular disease morbidity and mortality. Europace. 2010 May;12(5):626-33. doi: 10.1093/europace/euq109. PubMed PMID: 20421224; PubMed Central PMCID: PMC2859877. 424: Freestone B, Krishnamoorthy S, Lip GY. Assessment of endothelial dysfunction. Expert Rev Cardiovasc Ther. 2010 Apr;8(4):557-71. doi: 10.1586/erc.09.184. Review. PubMed PMID: 20397829. 425: Peter K, Lip GY. Thrombosis and cardiovascular disease: Exciting perspectives in cardiovascular prevention and therapy. Thromb Haemost. 2010 May;103(5):875-6. doi: 10.1160/TH10-03-0205. Epub 2010 Apr 13. PubMed PMID: 20390222. 426: Fauchier L, Lip GY. Guidelines for antithrombotic therapy in atrial fibrillation: understanding the reasons for non-adherence and moving forwards with simplifying risk stratification for stroke and bleeding. Europace. 2010 Jun;12(6):761-3. doi: 10.1093/europace/euq102. Epub 2010 Apr 12. Erratum in: Europace. 2010 Sep;12(9):1349. PubMed PMID: 20388635. 427: Prystowsky EN, Camm J, Lip GY, Allessie M, Bergmann JF, Breithardt G, Brugada J, Crijns H, Ellinor PT, Mark D, Naccarelli G, Packer D, Tamargo J. The impact of new and emerging clinical data on treatment strategies for atrial fibrillation. J Cardiovasc Electrophysiol. 2010 Aug 1;21(8):946-58. doi: 10.1111/j.1540-8167.2010.01770.x. Epub 2010 Apr 8. Review. PubMed PMID: 20384658. 428: Smith D, Lip GY, Lane DA. Impact of symptom control on health-related quality of life in atrial fibrillation patients: the psychologist's viewpoint. Europace. 2010 May;12(5):608-10. doi: 10.1093/europace/euq083. Epub 2010 Mar 30. PubMed PMID: 20353966. 429: Pisters R, Lane DA, Nieuwlaat R, de Vos CB, Crijns HJ, Lip GY. A novel user-friendly score (HAS-BLED) to assess 1-year risk of major bleeding in patients with atrial fibrillation: the Euro Heart Survey. Chest. 2010 Nov;138(5):1093-100. doi: 10.1378/chest.10-0134. Epub 2010 Mar 18. PubMed PMID: 20299623. 60 430: Siddique A, Shantsila E, Lip GY, Varma C. Endothelial progenitor cells: what use for the cardiologist? J Angiogenes Res. 2010 Feb 22;2:6. doi: 10.1186/2040-2384-2-6. PubMed PMID: 20298532; PubMed Central PMCID: PMC2834645. 431: Lip G, Miller J. Fast straining CT in assesment of difficult abdominal wall herniae. Surgeon. 2010 Feb;8(1):51-2. PubMed PMID: 20222403. 432: Closa León T, Nouwen A, Sheffield D, Jaumdally R, Lip GY. Anger rumination, social support, and cardiac symptoms in patients undergoing angiography. Br J Health Psychol. 2010 Nov;15(Pt 4):841-57. doi: 10.1348/135910710X491360. Epub 2010 Mar 4. PubMed PMID: 20205981. 433: Wrigley BJ, Lip GY, Shantsila E. Coronary atherosclerosis in rheumatoid arthritis: could endothelial progenitor cells be the missing link? J Rheumatol. 2010 Mar;37(3):479-81. doi: 10.3899/jrheum.091341. PubMed PMID: 20197563. 434: Tapp L, Shantsila E, Lip GY. Role of ticagrelor in clopidogrel nonresponders: resistance is futile? Circulation. 2010 Mar 16;121(10):1169-71. doi: 10.1161/CIR.0b013e3181d8d929. Epub 2010 Mar 1. PubMed PMID: 20194888. 435: Jaipersad AS, Silverman SH, Lip GY. Anti-platelet therapy: is it all over in peripheral artery disease? Thromb Haemost. 2010 Apr;103(4):689-91. doi: 10.1160/TH10-01-0053. Epub 2010 Feb 19. PubMed PMID: 20174749. 436: Barbalic M, Dupuis J, Dehghan A, Bis JC, Hoogeveen RC, Schnabel RB, Nambi V, Bretler M, Smith NL, Peters A, Lu C, Tracy RP, Aleksic N, Heeriga J, Keaney JF Jr, Rice K, Lip GY, Vasan RS, Glazer NL, Larson MG, Uitterlinden AG, Yamamoto J, Durda P, Haritunians T, Psaty BM, Boerwinkle E, Hofman A, Koenig W, Jenny NS, Witteman JC, Ballantyne C, Benjamin EJ. Large-scale genomic studies reveal central role of ABO in sP-selectin and sICAM-1 levels. Hum Mol Genet. 2010 May 1;19(9):1863-72. doi: 10.1093/hmg/ddq061. Epub 2010 Feb 18. PubMed PMID: 20167578; PubMed Central PMCID: PMC2850624. 437: Foster W, Carruthers D, Lip GY, Blann AD. Inflammation and microvascular and macrovascular endothelial dysfunction in rheumatoid arthritis: effect of treatment. J Rheumatol. 2010 Apr;37(4):711-6. doi: 10.3899/jrheum.090699. Epub 2010 Feb 15. PubMed PMID: 20156948. 61 438: Tapp L, Shantsila E, Lip GY. Aspirin--a drug whose time has gone? Am J Cardiol. 2010 Feb 15;105(4):577-8. doi: 10.1016/j.amjcard.2009.10.026. PubMed PMID: 20152256. 439: Rubboli A, Schlitt A, Airaksinen J, Lip GY. Bleeding after coronary stenting in patients on oral anticoagulation: who is guilty? EuroIntervention. 2010 Jan;5(6):649-50; author reply 651. PubMed PMID: 20142211. 440: Peter K, Lip GY. Changing the scope of preventative and therapeutic approaches in atherothrombosis. Thromb Haemost. 2010 Mar;103(3):487-8. doi: 10.1160/TH10-01-0063. Epub 2010 Feb 2. PubMed PMID: 20135057. 441: Lip GY. Anticoagulation therapy and the risk of stroke in patients with atrial fibrillation at 'moderate risk' [CHADS2 score=1]: simplifying stroke risk assessment and thromboprophylaxis in real-life clinical practice. Thromb Haemost. 2010 Apr;103(4):683-5. doi: 10.1160/TH10-01-0038. Epub 2010 Feb 2. PubMed PMID: 20135056. 442: Tello-Montoliu A, Marín F, Roldán V, Lip GY. The additive value of biomarkers to clinical risk scores in acute coronary syndrome. Are biomarkers really ready for real world usage? Heart. 2010 Feb;96(3):227-8; author reply 228. doi: 10.1136/hrt.2009.182105. PubMed PMID: 20133421. 443: Watson T, Shantsila E, Karthikeyan VJ, Jessani S, Goon PK, Lip GY. The effects of exercise stress testing, diurnal variation and temporal decline on circulating progenitor cells. Thromb Haemost. 2010 Feb;103(2):419-25. doi: 10.1160/TH09-06-0386. Epub 2009 Nov 13. PubMed PMID: 20126832. 444: Khoo CW, Lip GY. Insights from the dabigatran versus warfarin in patients with atrial fibrillation (RE-LY) trial. Expert Opin Pharmacother. 2010 Mar;11(4):685-7. doi: 10.1517/14656560903530691. PubMed PMID: 20105114. 445: Patel JV, Abraheem A, Creamer J, Gunning M, Hughes EA, Lip GY. Apolipoproteins in the discrimination of atherosclerotic burden and cardiac function in patients with stable coronary artery disease. Eur J Heart Fail. 2010 Mar;12(3):254-9. doi: 10.1093/eurjhf/hfp202. Epub 2010 Jan 19. PubMed PMID: 20089519. 62 446: Shantsila A, Lip GY. Towards (cost)effective cardiovascular risk management: using new drugs vs. the better use of available ones. Int J Clin Pract. 2010 Jan;64(2):138-40. doi: 10.1111/j.1742-1241.2009.02233.x. PubMed PMID: 20089004. 447: Lane DA, Lip GY. Anticoagulation for atrial fibrillation patients with CHADS score of 1. J Cardiovasc Electrophysiol. 2010 May;21(5):508-10. doi: 10.1111/j.1540-8167.2009.01687.x. Epub 2010 Jan 15. PubMed PMID: 20082649. 448: Lane DA, Lip GY. Anticoagulation intensity for elderly atrial fibrillation patients: should we use a conventional INR target (2.0 to 3.0) or a lower range? Thromb Haemost. 2010 Feb;103(2):254-6. doi: 10.1160/TH09-12-0843. Epub 2010 Jan 13. PubMed PMID: 20076858. 449: Weber C, Lip GY. Moving forward with a new editorial team for Thrombosis and Haemostasis. Thromb Haemost. 2010 Jan;103(1):1-2. Epub 2010 Jan 7. PubMed PMID: 20062942. 450: Lip GY, Huber K, Andreotti F, Arnesen H, Airaksinen KJ, Cuisset T, Kirchhof P, Marín F; European Society of Cardiology Working Group on Thrombosis. Management of antithrombotic therapy in atrial fibrillation patients presenting with acute coronary syndrome and/or undergoing percutaneous coronary intervention/ stenting. Thromb Haemost. 2010 Jan;103(1):13-28. doi: 10.1160/TH09-08-0580. Epub 2009 Sep 30. Review. Erratum in: Thromb Haemost. 2010 Sep;104(3):653. Dosage error in article text. PubMed PMID: 20062939. 451: Xu L, Jiang CQ, Lam TH, Lin JM, Yue XJ, Cheng KK, Liu B, Jin YL, Zhang WS, Thomas GN; Guangzhou Biobank Cohort Study-CVD. The metabolic syndrome is associated with subclinical atherosclerosis independent of insulin resistance: the Guangzhou Biobank Cohort Study-CVD. Clin Endocrinol (Oxf). 2010 Aug;73(2):181-8. doi: 10.1111/j.1365-2265.2009.03760.x. Epub 2009 Dec 18. PubMed PMID: 20039893. 452: Gray J, Edwards SJ, Lip GY. Comparison of sequential rosuvastatin doses in hypercholesterolaemia: a meta-analysis of randomised controlled trials. Curr Med Res Opin. 2010 Mar;26(3):537-47. doi: 10.1185/03007990903513980. Review. PubMed PMID: 20028194. 63 453: Jessani SS, Lane DA, Shantsila E, Watson T, Millane TA, Lip GY. Impaired glucose tolerance and endothelial damage, as assessed by levels of von Willebrand factor and circulating endothelial cells, following acute myocardial infarction. Ann Med. 2009;41(8):608-18. doi: 10.1080/07853890903159256. PubMed PMID: 20021313. 454: Tay KH, Lane DA, Lip GY. Balancing thromboembolism and bleeding risks: insights from anticoagulation for prosthetic heart valves. Chest. 2009 Dec;136(6):1451-2. doi: 10.1378/chest.09-1187. PubMed PMID: 19995760. 455: Rathcke CN, Kistorp C, Raymond I, Hildebrandt P, Gustafsson F, Lip GY, Faber J, Vestergaard H. Plasma YKL-40 levels are elevated in patients with chronic heart failure. Scand Cardiovasc J. 2010 Apr;44(2):92-9. doi: 10.3109/14017430903402218. PubMed PMID: 19961288. 456: Schwartz GG, Olsson AG, Ballantyne CM, Barter PJ, Holme IM, Kallend D, Leiter LA, Leitersdorf E, McMurray JJ, Shah PK, Tardif JC, Chaitman BR, Duttlinger-Maddux R, Mathieson J; dal-OUTCOMES Committees and Investigators. Rationale and design of the dal-OUTCOMES trial: efficacy and safety of dalcetrapib in patients with recent acute coronary syndrome. Am Heart J. 2009 Dec;158(6):896-901.e3. doi: 10.1016/j.ahj.2009.09.017. PubMed PMID: 19958854. 457: Siu CW, Watson T, Lai WH, Lee YK, Chan YH, Ng KM, Lau CP, Lip GY, Tse HF. Relationship of circulating endothelial progenitor cells to the recurrence of atrial fibrillation after successful conversion and maintenance of sinus rhythm. Europace. 2010 Apr;12(4):517-21. doi: 10.1093/europace/eup382. Epub 2009 Nov 30. PubMed PMID: 19951966. 458: Kozlowski D, Budrejko S, Lip GY, Mikhailidis DP, Rysz J, Raczak G, Banach M. Vernakalant hydrochloride for the treatment of atrial fibrillation. Expert Opin Investig Drugs. 2009 Dec;18(12):1929-37. doi: 10.1517/13543780903386246. PubMed PMID: 19938903. 459: Patel JV, Caslake MJ, Vyas A, Cruickshank JK, Prabhakaran D, Bhatnagar D, Reddy KS, Lip GY, Mackness MI, Hughes EA, Durrington PN. Triglycerides and small dense low density lipoprotein in the discrimination of coronary heart disease risk in South Asian populations. Atherosclerosis. 2010 Apr;209(2):579-84. doi: 10.1016/j.atherosclerosis.2009.10.010. Epub 2009 Oct 13. PubMed PMID: 19922937. 64 460: Lip G, Nichols DM. Measurement of defect angle in superior semicircular canal dehiscence. Clin Radiol. 2009 Dec;64(12):1210-3. doi: 10.1016/j.crad.2009.07.002. Epub 2009 Aug 8. PubMed PMID: 19913132. 461: Shantsila E, Lip GY. The role of monocytes in thrombotic disorders. Insights from tissue factor, monocyte-platelet aggregates and novel mechanisms. Thromb Haemost. 2009 Nov;102(5):916-24. doi: 10.1160/TH09-01-0023. Review. PubMed PMID: 19888530. 462: Apostolakis S, Shantsila E, Lip GY, Lane DA. Contra: "Anti-platelet therapy is an alternative to oral anticoagulation for atrial fibrillation". Thromb Haemost. 2009 Nov;102(5):914-5. doi: 10.1160/TH09-08-0563. PubMed PMID: 19888529. 463: Jessani S, Millane T, Lip GY. Vascular damage in impaired glucose tolerance: an unappreciated phenomenon? Curr Pharm Des. 2009;15(29):3417-32. Review. PubMed PMID: 19860688. 464: Kaireviciute D, Aidietis A, Lip GY. Pathophysiological insights into atrial fibrillation following cardiac surgery: implications for current pharmaceutical design. Curr Pharm Des. 2009;15(29):3367-83. Review. PubMed PMID: 19860685. 465: Watson T, Arya A, Sulke N, Lip GY. Relationship of indices of inflammation and thrombogenesis to arrhythmia burden in paroxysmal atrial fibrillation. Chest. 2010 Apr;137(4):869-76. doi: 10.1378/chest.09-1426. Epub 2009 Oct 26. PubMed PMID: 19858230. 466: Lane DA, Lip GY. Treatment of hypertension in peripheral arterial disease. Cochrane Database Syst Rev. 2009 Oct 7;(4):CD003075. doi: 10.1002/14651858.CD003075.pub2. Review. PubMed PMID: 19821300. 467: Apostolakis S, Shantsila E, Lip GY. Vascular imaging as a cardiovascular risk stratification tool in systemic lupus erythematosus. J Rheumatol. 2009 Oct;36(10):2141-3. doi: 10.3899/jrheum.090640. PubMed PMID: 19820217. 468: Shantsila E, Lip GY. Systemic inflammation as a driver of vascular calcification: a proof of concept. J Intern Med. 2009 Nov;266(5):453-6. doi: 10.1111/j.1365-2796.2009.02138.x. PubMed PMID: 19817967. 65 469: Patel JV, Tracey I, Hughes EA, Lip GY. Omega-3 polyunsaturated fatty acids: a necessity for a comprehensive secondary prevention strategy. Vasc Health Risk Manag. 2009;5:801-10. Epub 2009 Sep 24. Review. PubMed PMID: 19812692; PubMed Central PMCID: PMC2754093. 470: Apostolakis S, Lip GY, Shantsila E. Monocytes in heart failure: relationship to a deteriorating immune overreaction or a desperate attempt for tissue repair? Cardiovasc Res. 2010 Mar 1;85(4):649-60. doi: 10.1093/cvr/cvp327. Epub 2009 Oct 4. Review. PubMed PMID: 19805399. 471: Apostolakis S, Shantsila E, Lip GY. New anticoagulants for the prevention of deep venous thrombosis: time to consider cost effectiveness? Pharmacoeconomics. 2009;27(10):793-5. doi: 10.2165/11313780-000000000-00000. PubMed PMID: 19803535. 472: Shantsila A, Lip GY. Review: combining 2 classes of blood pressure-lowering drugs has an approximately additive effect on systolic blood pressure. Evid Based Med. 2009 Oct;14(5):142. doi: 10.1136/ebm.14.5.142. PubMed PMID: 19794017. 473: Gill PS, Davis R, Davies M, Freemantle N, Lip GY. Rationale and study design of a cross sectional study documenting the prevalence of Heart Failure amongst the minority ethnic communities in the UK: the E-ECHOES Study (Ethnic--Echocardiographic Heart of England Screening Study). BMC Cardiovasc Disord. 2009 Sep 30;9:47. doi: 10.1186/1471-2261-9-47. PubMed PMID: 19793391; PubMed Central PMCID: PMC2765971. 474: Tapp L, Wrigley B, Lip GY. Acute coronary syndromes: oral factor Xa inhibitors in acute coronary syndromes. Nat Rev Cardiol. 2009 Oct;6(10):619-20. doi: 10.1038/nrcardio.2009.160. PubMed PMID: 19773793. 475: Saura D, Marín F, Climent V, González J, Roldán V, Hernández-Romero D, Oliva MJ, Sabater M, de la Morena G, Lip GY, Valdés M. Left atrial remodelling in hypertrophic cardiomyopathy: relation with exercise capacity and biochemical markers of tissue strain and remodelling. Int J Clin Pract. 2009 Oct;63(10):1465-71. doi: 10.1111/j.1742-1241.2009.02127.x. PubMed PMID: 19769703. 476: Lip GY, Nieuwlaat R, Pisters R, Lane DA, Crijns HJ. Refining clinical risk stratification for predicting stroke and thromboembolism in atrial fibrillation using a novel risk factor-based approach: the euro heart survey on atrial 66 fibrillation. Chest. 2010 Feb;137(2):263-72. doi: 10.1378/chest.09-1584. Epub 2009 Sep 17. PubMed PMID: 19762550. 477: Van de Werf F, Bax J, Betriu A, Blomstrom-Lundqvist C, Crea F, Falk V, Filippatos G, Fox K, Huber K, Kastrati A, Rosengren A, Steg PG, Tubaro M, Verheugt F, Weidinger F, Weis M; Task Force per il Trattamento dell'Infarto Miocardico Acuto con; Sopraslivellamento del Tratto ST della Società Europea di Cardiologia, Vahanian A, Camm J, De Caterina R, Dean V, Dickstein K, Filippatos G, Funck-Brentano C, Hellemans I, Kristensen SD, McGregor K, Sechtem U, Silber S, Tendera M, Widimsky P, Zamorano JL, Silber S, Aguirre FV, Al-Attar N, Alegria E, Andreotti F, Benzer W, Breithardt O, Danchin N, Di Mario C, Dudek D, Gulba D, Halvorsen S, Kaufmann P, Kornowski R, Lip GY, Rutten F, Societá Europea di Cardiologia. [Management of acute myocardial infarction in patients presenting with persistent ST-segment elevation]. G Ital Cardiol (Rome). 2009 Jul;10(7):450-89. Italian. PubMed PMID: 19761103. 478: Jaumdally RJ, Goon PK, Varma C, Blann AD, Lip GY. Effects of atorvastatin on circulating CD34+/CD133+/ CD45- progenitor cells and indices of angiogenesis (vascular endothelial growth factor and the angiopoietins 1 and 2) in atherosclerotic vascular disease and diabetes mellitus. J Intern Med. 2010 Apr;267(4):385-93. doi: 10.1111/j.1365-2796.2009.02151.x. Epub 2009 Jul 16. PubMed PMID: 19754853. 479: Wrigley BJ, Lip GY. Can the WATCHMAN device truly PROTECT from stroke in atrial fibrillation? Lancet Neurol. 2009 Oct;8(10):877-8. doi: 10.1016/S1474-4422(09)70244-3. PubMed PMID: 19747647. 480: Subramaniam V, Davis RC, Shantsila E, Lip GY. Antithrombotic therapy for heart failure in sinus rhythm. Fundam Clin Pharmacol. 2009 Dec;23(6):705-17. doi: 10.1111/j.1472-8206.2009.00776.x. Epub 2009 Sep 4. Review. PubMed PMID: 19735305. 481: Wallentin L, Becker RC, Budaj A, Cannon CP, Emanuelsson H, Held C, Horrow J, Husted S, James S, Katus H, Mahaffey KW, Scirica BM, Skene A, Steg PG, Storey RF, Harrington RA; PLATO Investigators, Freij A, Thorsén M. Ticagrelor versus clopidogrel in patients with acute coronary syndromes. N Engl J Med. 2009 Sep 10;361(11):1045-57. doi: 10.1056/NEJMoa0904327. Epub 2009 Aug 30. PubMed PMID: 19717846. 482: Connolly SJ, Ezekowitz MD, Yusuf S, Eikelboom J, Oldgren J, Parekh A, Pogue J, Reilly PA, Themeles E, Varrone J, Wang S, Alings M, Xavier D, Zhu J, Diaz R, 67 Lewis BS, Darius H, Diener HC, Joyner CD, Wallentin L; RE-LY Steering Committee and Investigators. Dabigatran versus warfarin in patients with atrial fibrillation. N Engl J Med. 2009 Sep 17;361(12):1139-51. doi: 10.1056/NEJMoa0905561. Epub 2009 Aug 30. Erratum in: N Engl J Med. 2010 Nov 4;363(19):1877. PubMed PMID: 19717844. 483: Kozlowski D, Budrejko S, Lip GY, Rysz J, Mikhailidis DP, Raczak G, Banach M. Lone atrial fibrillation: what do we know? Heart. 2010 Apr;96(7):498-503. doi: 10.1136/hrt.2009.176321. Epub 2009 Aug 26. Review. PubMed PMID: 19713203. 484: Lip GY, Lane DA. Combination anticoagulant and antiplatelet therapy in atrial fibrillation patients. Rev Esp Cardiol. 2009 Sep;62(9):972-5. English, Spanish. PubMed PMID: 19712617. 485: Krishnamoorthy S, Lim SH, Lip GY. Assessment of endothelial (dys)function in atrial fibrillation. Ann Med. 2009;41(8):576-90. doi: 10.1080/07853890903160726. Review. PubMed PMID: 19711210. 486: Ip J, Waldo AL, Lip GY, Rothwell PM, Martin DT, Bersohn MM, Choucair WK, Akar JG, Wathen MS, Rohani P, Halperin JL; IMPACT Investigators. Multicenter randomized study of anticoagulation guided by remote rhythm monitoring in patients with implantable cardioverter-defibrillator and CRT-D devices: Rationale, design, and clinical characteristics of the initially enrolled cohort The IMPACT study. Am Heart J. 2009 Sep;158(3):364-370.e1. doi: 10.1016/j.ahj.2009.07.002. PubMed PMID: 19699858. 487: Krishnamoorthy S, Lip GY, Lane DA. Alcohol and illicit drug use as precipitants of atrial fibrillation in young adults: a case series and literature review. Am J Med. 2009 Sep;122(9):851-856.e3. doi: 10.1016/j.amjmed.2009.02.012. Review. PubMed PMID: 19699381. 488: Lane DA, Lip GY, Beevers DG. Improving survival of malignant hypertension patients over 40 years. Am J Hypertens. 2009 Nov;22(11):1199-204. doi: 10.1038/ajh.2009.153. Epub 2009 Aug 20. PubMed PMID: 19696746. 489: Kong PK, Connolly D, Varma C, Lip G, Millane T, Davis R, Ahmad R. High-risk myocardial infarction patients appear to derive more mortality benefit from short door-to-balloon time than low-risk patients. Int J Clin Pract. 2009 Dec;63(12):1693-701. doi: 10.1111/j.1742-1241.2009.02122.x. Epub 2009 Aug 20. 68 PubMed PMID: 19694835. 490: Lip GY, Rasmussen LH, Olsson SB, Jensen EC, Persson AL, Eriksson U, Wåhlander KF; Steering Committee. Oral direct thrombin inhibitor AZD0837 for the prevention of stroke and systemic embolism in patients with non-valvular atrial fibrillation: a randomized dose-guiding, safety, and tolerability study of four doses of AZD0837 vs. vitamin K antagonists. Eur Heart J. 2009 Dec;30(23):2897-907. doi: 10.1093/eurheartj/ehp318. Epub 2009 Aug 18. PubMed PMID: 19690349; PubMed Central PMCID: PMC2785945. 491: Shantsila A, Lip GY. ACP Journal Club. Review: Combining 2 classes of blood pressure-lowering drugs has an approximately additive effect on systolic blood pressure. Ann Intern Med. 2009 Aug 18;151(4):JC2-11. PubMed PMID: 19687485. 492: Shantsila E, Lip GY. The endothelium and thrombotic risk in heart failure. Thromb Haemost. 2009 Aug;102(2):185-7. doi: 10.1160/TH09-06-0344. PubMed PMID: 19652866. 493: Goon PK, Lip GY, Stonelake PS, Blann AD. Circulating endothelial cells and circulating progenitor cells in breast cancer: relationship to endothelial damage/dysfunction/apoptosis, clinicopathologic factors, and the Nottingham Prognostic Index. Neoplasia. 2009 Aug;11(8):771-9. PubMed PMID: 19649207; PubMed Central PMCID: PMC2713592. 494: Apostolakis S, Shantsila E, Lip GY. Angiopoietins and preeclampsia: new perspectives in the quest for markers. Am J Hypertens. 2009 Aug;22(8):820. doi: 10.1038/ajh.2009.108. PubMed PMID: 19638956. 495: Khoo CW, Lip GY. Can the NICE guidelines on the management of atrial fibrillation improve its management? Clin Med. 2009 Jun;9(3):207-9. PubMed PMID: 19634378. 496: Shantsila E, Lip GY. Angiopoietins in arterial hypertension: a mechanism of adaptation or a target for treatment? J Hypertens. 2009 Aug;27(8):1524-6. doi: 10.1097/HJH.0b013e32832dd5c4. PubMed PMID: 19622925. 497: Watson T, Karthikeyan VJ, Lip GY, Beevers DG. Atrial fibrillation in primary aldosteronism. J Renin Angiotensin Aldosterone Syst. 2009 Dec;10(4):190-4. doi: 69 10.1177/1470320309342734. Epub 2009 Jul 17. PubMed PMID: 19617274. 498: Krishnamoorthy S, Lip GY. Novel antiarrhythmic drugs in atrial fibrillation: focus on tedisamil. Expert Opin Investig Drugs. 2009 Aug;18(8):1191-6. doi: 10.1517/13543780903114150. Review. PubMed PMID: 19604120. 499: Foster W, Carruthers D, Lip GY, Blann AD. Inflammatory cytokines, endothelial markers and adhesion molecules in rheumatoid arthritis: effect of intensive anti-inflammatory treatment. J Thromb Thrombolysis. 2010 May;29(4):437-42. doi: 10.1007/s11239-009-0370-y. PubMed PMID: 19578810. 500: Shantsila E, Lip GY. Monocyte diversity in myocardial infarction. J Am Coll Cardiol. 2009 Jul 7;54(2):139-42. doi: 10.1016/j.jacc.2009.03.047. PubMed PMID: 19573730. 501: Krishnamoorthy S, Lip GY. Renin-angiotensin-aldosterone system blockade in atrial fibrillation and left atrial remodelling. Int J Clin Pract. 2009 Jul;63(7):982-5. doi: 10.1111/j.1742-1241.2009.02083.x. PubMed PMID: 19570114. 502: Tay KH, Khoo CW, Lip GY. Mitral regurgitation reduces systemic coagulation activity in rheumatic heart disease: using fibrin D-dimer as a biomarker of thrombogenesis. J Heart Valve Dis. 2009 May;18(3):276-7. PubMed PMID: 19557982. 503: Lim HS, Lip GY. Defibrillation testing in patients with atrial fibrillation. Europace. 2009 Aug;11(8):1108-9. doi: 10.1093/europace/eup157. Epub 2009 Jun 23. PubMed PMID: 19549676. 504: Marín F, Kirchhof P, Lip GY. Antithrombotic therapy use for patients with atrial fibrillation undergoing percutaneous coronary intervention: new data in an area of limited evidence. Europace. 2009 Jul;11(7):842-3. doi: 10.1093/europace/eup161. PubMed PMID: 19546184. 505: Krishnamoorthy S, Lip GY. How safe is the antiarrhythmic drug therapy in atrial fibrillation? Europace. 2009 Jul;11(7):837-9. doi: 10.1093/europace/eup170. PubMed PMID: 19546182. 506: Tay KH, Lip GY, Lane DA. Bleeding rates in elderly patients on vitamin K 70 antagonist therapy for nonvalvular atrial fibrillation. Blood Coagul Fibrinolysis. 2009 Jul;20(5):392-3. doi: 10.1097/MBC.0b013e32832aec47. PubMed PMID: 19542940. 507: Kirchhof P, Bax J, Blomstrom-Lundquist C, Calkins H, Camm AJ, Cappato R, Cosio F, Crijns H, Diener HC, Goette A, Israel CW, Kuck KH, Lip GY, Nattel S, Page RL, Ravens U, Schotten U, Steinbeck G, Vardas P, Waldo A, Wegscheider K, Willems S, Breithardt G. Early and comprehensive management of atrial fibrillation: executive summary of the proceedings from the 2nd AFNET-EHRA consensus conference 'research perspectives in AF'. Eur Heart J. 2009 Dec;30(24):2969-77c. doi: 10.1093/eurheartj/ehp235. Epub . PubMed PMID: 19535417. 508: Kirchhof P, Bax J, Blomstrom-Lundquist C, Calkins H, Camm AJ, Cappato R, Cosio F, Crijns H, Diener HC, Goette A, Israel CW, Kuck KH, Lip GY, Nattel S, Page RL, Ravens U, Schotten U, Steinbeck G, Vardas P, Waldo A, Wegscheider K, Willems S, Breithardt G. Early and comprehensive management of atrial fibrillation: proceedings from the 2nd AFNET/EHRA consensus conference on atrial fibrillation entitled 'research perspectives in atrial fibrillation'. Europace. 2009 Jul;11(7):860-85. doi: 10.1093/europace/eup124. Epub 2009 Jun 16. PubMed PMID: 19531542. 509: Gunarathne A, Patel JV, Kausar S, Gammon B, Hughes EA, Lip GY. Glycemic status underlies increased arterial stiffness and impaired endothelial function in migrant South Asian stroke survivors compared to European Caucasians: pathophysiological insights from the West Birmingham Stroke Project. Stroke. 2009 Jul;40(7):2298-306. doi: 10.1161/STROKEAHA.109.548388. Epub 2009 Jun 11. PubMed PMID: 19520993. 510: Butt M, Dwivedi G, Khair O, Lip GY. Obstructive sleep apnea and cardiovascular disease. Int J Cardiol. 2010 Feb 18;139(1):7-16. doi: 10.1016/j.ijcard.2009.05.021. Epub 2009 Jun 7. Review. PubMed PMID: 19505734. 511: Subramaniam V, Lip GY. Hypertension to heart failure: a pathophysiological spectrum relating blood pressure, drug treatments and stroke. Expert Rev Cardiovasc Ther. 2009 Jun;7(6):703-13. doi: 10.1586/erc.09.43. PubMed PMID: 19505285. 512: Nadar SK, Goyal D, Shantsila E, Banerjee P, Lip GY. Fondaparinux: an overview. Expert Rev Cardiovasc Ther. 2009 Jun;7(6):577-85. doi: 10.1586/erc.09.19. PubMed PMID: 19505272. 71 513: Butt M, Dwivedi G, Khair O, Lip GY. Assessment of endothelial function: implications for hypertension and cardiovascular disorders. Expert Rev Cardiovasc Ther. 2009 Jun;7(6):561-3. doi: 10.1586/erc.09.36. PubMed PMID: 19505269. 514: Shantsila E, Lip GY, Chong BH. Heparin-induced thrombocytopenia. A contemporary clinical approach to diagnosis and management. Chest. 2009 Jun;135(6):1651-64. doi: 10.1378/chest.08-2830. Review. PubMed PMID: 19497901. 515: Bennett PC, Silverman SH, Gill PS, Lip GY. Peripheral arterial disease and Virchow's triad. Thromb Haemost. 2009 Jun;101(6):1032-40. Review. PubMed PMID: 19492144. 516: Shantsila E, Lip GY. Endothelial function and endothelial progenitors: possible mediators of the benefits from physical exercise? Eur J Cardiovasc Prev Rehabil. 2009 Aug;16(4):401-3. doi: 10.1097/HJR.0b013e32832d3c76. PubMed PMID: 19491685. 517: Ruiz-Nodar JM, Marín F, Lip GY. Antithrombotic therapy use after percutaneous coronary intervention and stent implantation in patients taking chronic oral anticoagulation. JACC Cardiovasc Interv. 2008 Jun;1(3):329; author reply 330-1. doi: 10.1016/j.jcin.2008.03.016. PubMed PMID: 19463322. 518: Apostolakis S, Shantsila E, Lip GY. Evidence guided antiplatelet treatment: time to move from bench to bedside. Thromb Res. 2009 Dec;124(6):649-50. doi: 10.1016/j.thromres.2009.04.020. Epub 2009 May 14. PubMed PMID: 19443018. 519: Ng Kam Chuen MJ, Lip GY, Macfadyen RJ. Performing repeated noninvasive bedside measures of volume response to intravenous furosemide in acute pulmonary edema: a feasibility assessment. Cardiovasc Ther. 2009 Summer;27(2):89-95. doi: 10.1111/j.1755-5922.2009.00080.x. PubMed PMID: 19426245. 520: Krishnamoorthy S, Lip GY. Antiarrhythmic drugs for atrial fibrillation: focus on dronedarone. Expert Rev Cardiovasc Ther. 2009 May;7(5):473-81. doi: 10.1586/erc.09.14. Review. PubMed PMID: 19419255. 521: Lane DA, Lip GY. Female gender is a risk factor for stroke and 72 thromboembolism in atrial fibrillation patients. Thromb Haemost. 2009 May;101(5):802-5. Erratum in: Thromb Haemost.2010 Sep;104(3):653. PubMed PMID: 19404530. 522: Task Force members, Brignole M, Vardas P, Hoffman E, Huikuri H, Moya A, Ricci R, Sulke N, Wieling W; EHRA Scientific Documents Committee, Auricchio A, Lip GY, Almendral J, Kirchhof P, Aliot E, Gasparini M, Braunschweig F; Document Reviewers, Lip GY, Almendral J, Kirchhof P, Botto GL; EHRA Scientific Documents Committee. Indications for the use of diagnostic implantable and external ECG loop recorders. Europace. 2009 May;11(5):671-87. doi: 10.1093/europace/eup097. Review. Erratum in: Europace. 2009 Jun;11(6):836. PubMed PMID: 19401342. 523: Siddique A, Butt M, Shantsila E, Lip GY. New antiplatelet drugs: beyond aspirin and clopidogrel. Int J Clin Pract. 2009 May;63(5):776-89. doi: 10.1111/j.1742-1241.2009.02058.x. Review. PubMed PMID: 19392926. 524: Gunarathne A, Patel JV, Gammon B, Gill PS, Hughes EA, Lip GY. Ischemic stroke in South Asians: a review of the epidemiology, pathophysiology, and ethnicity-related clinical features. Stroke. 2009 Jun;40(6):e415-23. doi: 10.1161/STROKEAHA.108.535724. Epub 2009 Apr 23. Review. PubMed PMID: 19390072. 525: Khoo CW, Lip GY. Clinical outcomes of acute stroke patients with atrial fibrillation. Expert Rev Cardiovasc Ther. 2009 Apr;7(4):371-4. doi: 10.1586/erc.09.11. PubMed PMID: 19379061. 526: Patel JV, Tracey I, Hughes EA, Lip GY. Unraveling the paradoxical link between obesity and heart failure: the role of adipocytokines. Expert Rev Cardiovasc Ther. 2009 Apr;7(4):337-40. doi: 10.1586/erc.09.12. PubMed PMID: 19379057. 527: Butt M, Connolly D, Lip GY. Drug-eluting stents: a comprehensive appraisal. Future Cardiol. 2009 Mar;5(2):141-57. doi: 10.2217/14796678.5.2.141. Review. PubMed PMID: 19371189. 528: Khoo CW, Lip GY. Burden of atrial fibrillation. Curr Med Res Opin. 2009 May;25(5):1261-3. doi: 10.1185/03007990902910443 . PubMed PMID: 19366300. 529: Hamaad A, Sosin MD, Blann AD, Lip GY, MacFadyen RJ. Markers of thrombosis 73 and hemostasis in acute coronary syndromes: relationship to increased heart rate and reduced heart-rate variability. Clin Cardiol. 2009 Apr;32(4):204-9. doi: 10.1002/clc.20321. PubMed PMID: 19353696. 530: ACTIVE Investigators, Connolly SJ, Pogue J, Hart RG, Hohnloser SH, Pfeffer M, Chrolavicius S, Yusuf S. Effect of clopidogrel added to aspirin in patients with atrial fibrillation. N Engl J Med. 2009 May 14;360(20):2066-78. doi: 10.1056/NEJMoa0901301. Epub 2009 Mar 31. PubMed PMID: 19336502. 531: Siddique A, Shantsila E, Lip GY. AZD6140 and bleeding: towards safer antiplatelet therapy? Int J Clin Pract. 2009 Apr;63(4):537-9. doi: 10.1111/j.1742-1241.2008.01963.x. PubMed PMID: 19335702. 532: Krishnamoorthy S, Lip GY. Response to Dr Kula: Asymptomatic hypoxia in a young pregnant lady--unusual presentation of atrial septal defect. Int J Cardiol. 2010 Oct 29;144(3):428. doi: 10.1016/j.ijcard.2009.03.047. Epub 2009 Mar 26. PubMed PMID: 19327853. 533: Du X, Ninomiya T, de Galan B, Abadir E, Chalmers J, Pillai A, Woodward M, Cooper M, Harrap S, Hamet P, Poulter N, Lip GY, Patel A; ADVANCE Collaborative Group. Risks of cardiovascular events and effects of routine blood pressure lowering among patients with type 2 diabetes and atrial fibrillation: results of the ADVANCE study. Eur Heart J. 2009 May;30(9):1128-35. doi: 10.1093/eurheartj/ehp055. Epub 2009 Mar 11. PubMed PMID: 19282274. 534: Pineda J, Marín F, Marco P, Roldán V, Valencia J, Ruiz-Nodar JM, Romero DH, Sogorb F, Lip GY. The prognostic value of biomarkers after a premature myocardial infarction. Int J Cardiol. 2010 Sep 3;143(3):249-54. doi: 10.1016/j.ijcard.2009.02.019. Epub 2009 Mar 17. PubMed PMID: 19278741. 535: Tay KH, Lip GY, Lane DA. Atrial fibrillation and stroke risk prevention in real-life clinical practice. Thromb Haemost. 2009 Mar;101(3):415-6. PubMed PMID: 19277398. 536: Shantsila E, Lip GY. Variability of response to antiplatelet therapy: what should we do next? Fundam Clin Pharmacol. 2009 Feb;23(1):19-22. doi: 10.1111/j.1472-8206.2008.00674.x. PubMed PMID: 19267768. 74 537: Khoo CW, Lip GY. Acute management of atrial fibrillation. Chest. 2009 Mar;135(3):849-59. doi: 10.1378/chest.08-2183. Review. PubMed PMID: 19265095. 538: Ruiz-Nodar JM, Marín F, Sánchez-Payá J, Hurtado JA, Valencia-Martín J, Manzano-Fernández S, Roldán V, Pérez-Andreu V, Sogorb F, Valdés M, Lip GY. Efficacy and safety of drug-eluting stent use in patients with atrial fibrillation. Eur Heart J. 2009 Apr;30(8):932-9. doi: 10.1093/eurheartj/ehp045. Epub 2009 Feb 26. PubMed PMID: 19246502. 539: Lane DA, Langman CM, Lip GY, Nouwen A. Illness perceptions, affective response, and health-related quality of life in patients with atrial fibrillation. J Psychosom Res. 2009 Mar;66(3):203-10. doi: 10.1016/j.jpsychores.2008.10.007. PubMed PMID: 19232232. 540: Shantsila E, Lip GY. Monocytes in acute coronary syndromes. Arterioscler Thromb Vasc Biol. 2009 Oct;29(10):1433-8. doi: 10.1161/ATVBAHA.108.180513. Epub 2009 Feb 19. Review. PubMed PMID: 19229072. 541: Jaumdally RJ, Lip GY, Patel JV, MacFadyen RJ, Varma C. Effects of coronary artery disease and percutaneous intervention on the cardiac metabolism of nonesterified fatty acids and insulin: Implications of diabetes mellitus. J Intern Med. 2009 Jun;265(6):689-97. doi: 10.1111/j.1365-2796.2009.02072.x. Epub 2009 Feb 16. PubMed PMID: 19226374. 542: Khoo CW, Tay KH, Shantsila E, Lip GY. Novel oral anticoagulants. Int J Clin Pract. 2009 Apr;63(4):630-41. doi: 10.1111/j.1742-1241.2009.02011.x. Epub 2009 Feb 16. Review. PubMed PMID: 19222611. 543: Goyal D, Logie IM, Nadar SK, Lip GY, Macfadyen RJ. Generalized obesity but not that characterized by raised waist-hip ratio is associated with increased perceived breathlessness during treadmill exercise testing. Cardiovasc Ther. 2009 Spring;27(1):10-6. doi: 10.1111/j.1755-5922.2008.00067.x. PubMed PMID: 19207475. 544: Tay KH, Lip GY, Lane DA. Anticoagulation variability: is it the physician, patient or hospital? J Intern Med. 2009 Mar;265(3):303-6. doi: 10.1111/j.1365-2796.2008.02069.x. PubMed PMID: 19207370. 545: Patel JV, Abraheem A, Chackathayil J, Gunning M, Creamer J, Hughes EA, Lip 75 GY. Circulating biomarkers of angiogenesis as indicators of left ventricular systolic dysfunction amongst patients with coronary artery disease. J Intern Med. 2009 May;265(5):562-7. doi: 10.1111/j.1365-2796.2008.02057.x. Epub 2009 Jan 31. PubMed PMID: 19187100. 546: Bhatia GS, Sosin MD, Patel JV, Grindulis KA, Khattak FH, Davis RC, Lip GY. Plasma indices of angiogenesis in rheumatoid disease: relationship to cardiovascular risk factors and cardiac function. Int J Cardiol. 2010 Dec 3;145(3):e105-8. doi: 10.1016/j.ijcard.2008.12.168. Epub 2009 Jan 29. PubMed PMID: 19185362. 547: Kaireviciute D, Aidietis A, Lip GY. Atrial fibrillation following cardiac surgery: clinical features and preventative strategies. Eur Heart J. 2009 Feb;30(4):410-25. doi: 10.1093/eurheartj/ehn609. Epub 2009 Jan 27. Review. PubMed PMID: 19174427. 548: Patel JV, Lim HS, Dubb K, Hughes EA, Lip GY. Circulating levels of adiponectin, leptin, and tumour necrosis factor alpha in hypertension. Ann Med. 2009;41(4):291-300. doi: 10.1080/07853890802672839. PubMed PMID: 19172446. 549: Jolly K, Taylor RS, Lip GY, Davies M, Davis R, Mant J, Singh S, Greenfield S, Ingram J, Stubley J, Bryan S, Stevens A. A randomized trial of the addition of home-based exercise to specialist heart failure nurse care: the Birmingham Rehabilitation Uptake Maximisation study for patients with Congestive Heart Failure (BRUM-CHF) study. Eur J Heart Fail. 2009 Feb;11(2):205-13. doi: 10.1093/eurjhf/hfn029. PubMed PMID: 19168520; PubMed Central PMCID: PMC2639417. 550: Patel JV, Sosin M, Gunarathne A, Hussain I, Davis RC, Hughes EA, Lip GY. Elevated angiogenin levels in chronic heart failure. Ann Med. 2008;40(6):474-9. doi: 10.1080/07853890802001419. PubMed PMID: 19160530. 551: Krishnamoorthy S, Butt M, Lip GY. Asymptomatic hypoxia in a young pregnant lady--unusual presentation of atrial septal defect. Int J Cardiol. 2010 Aug 20;143(2):e34-6. doi: 10.1016/j.ijcard.2008.12.039. Epub 2009 Jan 21. PubMed PMID: 19157590. 552: Tay KH, Lane DA, Lip GY. Challenges facing anticoagulation among the elderly and frail. Age Ageing. 2009 Mar;38(2):140-2. doi: 10.1093/ageing/afn295. Epub 2009 Jan 20. PubMed PMID: 19155538. 76 553: Foster W, Shantsila E, Carruthers D, Lip GY, Blann AD. Circulating endothelial cells and rheumatoid arthritis: relationship with plasma markers of endothelial damage/dysfunction. Rheumatology (Oxford). 2009 Mar;48(3):285-8. doi: 10.1093/rheumatology/ken486. Epub 2009 Jan 19. PubMed PMID: 19153145. 554: Lip GY, Krishnamoorthy S. Thrombosis prophylaxis in patients with ischaemic (cardioembolic) stroke. How long is long enough? Hamostaseologie. 2009 Jan;29(1):96-101. Review. PubMed PMID: 19151857. 555: Cambronero F, Marín F, Roldán V, Hernández-Romero D, Valdés M, Lip GY. Biomarkers of pathophysiology in hypertrophic cardiomyopathy: implications for clinical management and prognosis. Eur Heart J. 2009 Jan;30(2):139-51. doi: 10.1093/eurheartj/ehn538. Epub 2009 Jan 9. Review. PubMed PMID: 19136482. 556: Watson T, Shantsila E, Lip GY. Mechanisms of thrombogenesis in atrial fibrillation: Virchow's triad revisited. Lancet. 2009 Jan 10;373(9658):155-66. doi: 10.1016/S0140-6736(09)60040-4. Review. PubMed PMID: 19135613. 557: Shantsila E, Lip GY. Predicting thrombotic events: creating a complex approach for a complex condition. Thromb Haemost. 2008 Dec;100(6):962-4. PubMed PMID: 19132217. 558: Tay KH, Lane DA, Lip GY. Bleeding risks with combination of oral anticoagulation plus antiplatelet therapy: is clopidogrel any safer than aspirin when combined with warfarin? Thromb Haemost. 2008 Dec;100(6):955-7. PubMed PMID: 19132214. 559: Preissner KT, Lip GY. Face to face with basic and clinical research in Thrombosis and Haemostasis. Thromb Haemost. 2009 Jan;101(1):1. PubMed PMID: 19132178. 560: Brugts JJ, de Maat MP, Boersma E, Witteman JC, van Duijn C, Uitterlinden AG, Bertrand M, Remme W, Fox K, Ferrari R, Danser AH, Simoons ML; EUROPA-PERGENE investigators. The rationale and design of the PERindopril GENEtic association study (PERGENE): a pharmacogenetic analysis of angiotensin-converting enzyme inhibitor therapy in patients with stable coronary artery disease. Cardiovasc Drugs Ther. 2009 Apr;23(2):171-81. doi: 10.1007/s10557-008-6156-1. Epub 2008 Dec 77 10. PubMed PMID: 19082699. 561: Khoo CW, Lip GY. Radiofrequency catheter ablation of atrial fibrillation and thromboembolic risk. Eur J Neurol. 2008 Dec;15(12):1261-2. doi: 10.1111/j.1468-1331.2008.02342.x. PubMed PMID: 19049540. 562: Lane DA, Lip GY. Quality of life in older people with atrial fibrillation. J Interv Card Electrophysiol. 2009 Jun;25(1):37-42. doi: 10.1007/s10840-008-9318-y. Epub 2008 Nov 26. Review. PubMed PMID: 19034639. 563: Tay KH, Lip GY. What "drives" the link between the renin-angiotensin-aldosterone system and the prothrombotic state in hypertension? Am J Hypertens. 2008 Dec;21(12):1278-9. doi: 10.1038/ajh.2008.315. PubMed PMID: 19020509. 564: Butt M, Lip GY. The endothelium, arterial stiffness, and von Willebrand factor levels in hypertensive women: effects of ethnicity. Am J Hypertens. 2008 Dec;21(12):1275-6. doi: 10.1038/ajh.2008.303. PubMed PMID: 19020507. 565: Krishnamoorthy S, Lip GY. Hypertension, stroke and the impact of atrial fibrillation. Expert Rev Cardiovasc Ther. 2008 Nov;6(10):1287-9. doi: 10.1586/14779072.6.10.1287. PubMed PMID: 19018678. 566: Manzano-Fernández S, Marín F, Pastor-Pérez FJ, Caro C, Cambronero F, Lacunza J, Pinar E, Pascual-Figal DA, Valdés M, Lip GY. Impact of chronic kidney disease on major bleeding complications and mortality in patients with indication for oral anticoagulation undergoing coronary stenting. Chest. 2009 Apr;135(4):983-90. doi: 10.1378/chest.08-1425. Epub 2008 Nov 18. PubMed PMID: 19017872. 567: Van de Werf F, Bax J, Betriu A, Blomstrom-Lundqvist C, Crea F, Falk V, Filippatos G, Fox K, Huber K, Kastrati A, Rosengren A, Steg PG, Tubaro M, Verheugt F, Weidinger F, Weis M; ESC Committee for Practice Guidelines (CPG). Management of acute myocardial infarction in patients presenting with persistent ST-segment elevation: the Task Force on the Management of ST-Segment Elevation Acute Myocardial Infarction of the European Society of Cardiology. Eur Heart J. 2008 Dec;29(23):2909-45. doi: 10.1093/eurheartj/ehn416. Epub 2008 Nov 12. PubMed PMID: 19004841. 78 568: Pastor-Pérez FJ, Marín F, Manzano-Fernández S, Lip GY. Is thrombogenesis related to residual platelet function in ischaemic heart disease? Eur Heart J. 2008 Dec;29(24):3065; author reply 3065-6. doi: 10.1093/eurheartj/ehn472. Epub 2008 Oct 25. PubMed PMID: 18953049. 569: Bennett PC, Silverman S, Gill PS, Lip GY. Ethnicity and peripheral artery disease. QJM. 2009 Jan;102(1):3-16. doi: 10.1093/qjmed/hcn140. Epub 2008 Oct 23. Review. PubMed PMID: 18948371. 570: Lip GY, Butt M. Gender and the response to blood pressure-lowering treatment. Eur Heart J. 2008 Nov;29(21):2585-6. doi: 10.1093/eurheartj/ehn451. Epub 2008 Oct 13. PubMed PMID: 18852182. 571: Freestone B, Lip GY. The endothelium and atrial fibrillation. The prothrombotic state revisited. Hamostaseologie. 2008 Oct;28(4):207-12. Review. PubMed PMID: 18836646. 572: Patel JV, Abraheem A, Dotsenko O, Creamer J, Gunning M, Hughes EA, Lip GY. Circulating serum adiponectin levels in patients with coronary artery disease: relationship to atherosclerotic burden and cardiac function. J Intern Med. 2008 Dec;264(6):593-8. doi: 10.1111/j.1365-2796.2008.02007.x. Epub 2008 Sep 10. PubMed PMID: 18793246. 573: Lip GY. Managing the anticoagulated patient with atrial fibrillation at high risk of stroke who needs coronary intervention. BMJ. 2008 Sep 12;337:a840. doi: 10.1136/bmj.39533.570602.BE. Erratum in: BMJ. 2008;337:a1721. PubMed PMID: 18790815. 574: Idriss NK, Blann AD, Lip GY. Hemoxygenase-1 in cardiovascular disease. J Am Coll Cardiol. 2008 Sep 16;52(12):971-8. doi: 10.1016/j.jacc.2008.06.019. Review. PubMed PMID: 18786476. 575: Dotsenko O, Chackathayil J, Patel JV, Gill PS, Lip GY. Candidate circulating biomarkers for the cardiovascular disease continuum. Curr Pharm Des. 2008;14(24):2445-61. Review. PubMed PMID: 18781994. 576: Boos CJ, Balakrishnan B, Blann AD, Lip GY. The relationship of circulating endothelial cells to plasma indices of endothelial damage/dysfunction and 79 apoptosis in acute coronary syndromes: implications for prognosis. J Thromb Haemost. 2008 Nov;6(11):1841-50. doi: 10.1111/j.1538-7836.2008.03148.x. Epub 2008 Aug 28. PubMed PMID: 18761720. 577: Shantsila E, Lip GY. 'Aspirin resistance' or treatment non-compliance: which is to blame for cardiovascular complications? J Transl Med. 2008 Aug 29;6:47. doi: 10.1186/1479-5876-6-47. PubMed PMID: 18759979; PubMed Central PMCID: PMC2535592. 578: Diener HC, Sacco RL, Yusuf S, Cotton D, Ounpuu S, Lawton WA, Palesch Y, Martin RH, Albers GW, Bath P, Bornstein N, Chan BP, Chen ST, Cunha L, Dahlöf B, De Keyser J, Donnan GA, Estol C, Gorelick P, Gu V, Hermansson K, Hilbrich L, Kaste M, Lu C, Machnig T, Pais P, Roberts R, Skvortsova V, Teal P, Toni D, VanderMaelen C, Voigt T, Weber M, Yoon BW; Prevention Regimen for Effectively Avoiding Second Strokes (PRoFESS) study group. Effects of aspirin plus extended-release dipyridamole versus clopidogrel and telmisartan on disability and cognitive function after recurrent stroke in patients with ischaemic stroke in the Prevention Regimen for Effectively Avoiding Second Strokes (PRoFESS) trial: a double-blind, active and placebo-controlled study. Lancet Neurol. 2008 Oct;7(10):875-84. doi: 10.1016/S1474-4422(08)70198-4. Epub 2008 Aug 29. Erratum in: Lancet Neurol. 2008 Nov;7(11):985. PubMed PMID: 18757238; PubMed Central PMCID: PMC2772657. 579: Yusuf S, Diener HC, Sacco RL, Cotton D, Ounpuu S, Lawton WA, Palesch Y, Martin RH, Albers GW, Bath P, Bornstein N, Chan BP, Chen ST, Cunha L, Dahlöf B, De Keyser J, Donnan GA, Estol C, Gorelick P, Gu V, Hermansson K, Hilbrich L, Kaste M, Lu C, Machnig T, Pais P, Roberts R, Skvortsova V, Teal P, Toni D, VanderMaelen C, Voigt T, Weber M, Yoon BW; PRoFESS Study Group. Telmisartan to prevent recurrent stroke and cardiovascular events. N Engl J Med. 2008 Sep 18;359(12):1225-37. doi: 10.1056/NEJMoa0804593. Epub 2008 Aug 27. PubMed PMID: 18753639; PubMed Central PMCID: PMC2714258. 580: Sacco RL, Diener HC, Yusuf S, Cotton D, Ounpuu S, Lawton WA, Palesch Y, Martin RH, Albers GW, Bath P, Bornstein N, Chan BP, Chen ST, Cunha L, Dahlöf B, De Keyser J, Donnan GA, Estol C, Gorelick P, Gu V, Hermansson K, Hilbrich L, Kaste M, Lu C, Machnig T, Pais P, Roberts R, Skvortsova V, Teal P, Toni D, Vandermaelen C, Voigt T, Weber M, Yoon BW; PRoFESS Study Group. Aspirin and extended-release dipyridamole versus clopidogrel for recurrent stroke. N Engl J Med. 2008 Sep 18;359(12):1238-51. doi: 10.1056/NEJMoa0805002. Epub 2008 Aug 27. PubMed PMID: 18753638; PubMed Central PMCID: PMC2714259. 80 581: Shantsila E, Lip GY. Apixaban, an oral, direct inhibitor of activated Factor Xa. Curr Opin Investig Drugs. 2008 Sep;9(9):1020-33. Review. PubMed PMID: 18729009. 582: Sánchez-Quiñones J, Marín F, Roldán V, Lip GY. The impact of statin use on atrial fibrillation. QJM. 2008 Nov;101(11):845-61. doi: 10.1093/qjmed/hcn101. Epub 2008 Aug 24. Review. PubMed PMID: 18725372. 583: López-Cuenca A, Marín F, Roldán V, Climent VE, Valdés M, Lip GY. Effects of atorvastatin 80 mg daily on indices of matrix remodelling in 'high-risk' patients with ischemic heart disease. Int J Cardiol. 2010 Feb 18;139(1):95-7. doi: 10.1016/j.ijcard.2008.06.076. Epub 2008 Aug 22. PubMed PMID: 18722681. 584: Jones MI, Greenfield S, Jolly K; BRUM Trial Steering Committee. Patients' experience of home and hospital based cardiac rehabilitation: a focus group study. Eur J Cardiovasc Nurs. 2009 Mar;8(1):9-17. doi: 10.1016/j.ejcnurse.2008.06.001. Epub 2008 Aug 21. PubMed PMID: 18718816. 585: Vardas PE, Auricchio A, Blanc JJ, Daubert JC, Drexler H, Ector H, Gasparini M, Linde C, Morgado FB, Oto A, Sutton R, Trusz-Gluza M; Grupo de Trabalho para Pacing Cardíaco e Terapia de Ressincronização Cardíaca da European Society of Cardiology; European Heart Rhythm Association, Vahanian A, Camm J, De Caterina R, Dean V, Dickstein K, Funck-Brentano C, Filippatos G, Hellemans I, Kristensen SD, McGregor K, Sechtem U, Silber S, Tendera M, Widimsky P, Zamorano JL, Priori SG, Blomström-Lundqvist C, Brignole M, Terradellas JB, Camm J, Castellano P, Cleland J, Farre J, Fromer M, Le Heuzey JY, Lip GY, Merino JL, Montenero AS, Ritter P, Schalij MJ, Stellbrink C. [Guidelines for cardiac pacing and cardiac resynchronization therapy]. Rev Port Cardiol. 2008 May;27(5):639-87. Portuguese. PubMed PMID: 18717216. 586: Foster W, Carruthers D, Lip GY, Blann AD. Relationships between endothelial, inflammatory and angiogenesis markers in rheumatoid arthritis: implications for cardiovascular pathophysiology. Thromb Res. 2009 Feb;123(4):659-64. doi: 10.1016/j.thromres.2008.06.014. Epub 2008 Aug 8. PubMed PMID: 18692223. 587: Khoo CW, Lip GY. Initiation and persistence of warfarin or aspirin as thromboprophylaxis in chronic atrial fibrillation in general practice. J Thromb Haemost. 2008 Oct;6(10):1622-4. doi: 10.1111/j.1538-7836.2008.03115.x. Epub 2008 Aug 1. Review. PubMed PMID: 18680537. 81 588: Manzano-Fernández S, Marin F, Martinez JA, Cambronero F, Valdés M, Ruiz-Nodar JM, Pérez-Berbel P, Lip GY. Anaemia as predictor of gastrointestinal bleeding in atrial fibrillation patients undergoing percutaneous coronary artery stenting. QJM. 2008 Sep;101(9):749-51. doi: 10.1093/qjmed/hcn082. Epub 2008 Jul 29. PubMed PMID: 18664533. 589: Singer DE, Albers GW, Dalen JE, Fang MC, Go AS, Halperin JL, Lip GY, Manning WJ; American College of Chest Physicians. Antithrombotic therapy in atrial fibrillation: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition). Chest. 2008 Jun;133(6 Suppl):546S-592S. doi: 10.1378/chest.08-0678. PubMed PMID: 18574273. 590: Choudhury A, Chung I, Panja N, Patel J, Lip GY. Soluble CD40 ligand, platelet surface CD40 ligand, and total platelet CD40 ligand in atrial fibrillation: relationship to soluble P-selectin, stroke risk factors, and risk factor intervention. Chest. 2008 Sep;134(3):574-81. doi: 10.1378/chest.07-2745. Epub 2008 Jul 18. PubMed PMID: 18641098. 591: Manzano-Fernández S, Pastor FJ, Marín F, Cambronero F, Caro C, Pascual-Figal DA, Garrido IP, Pinar E, Valdés M, Lip GY. Increased major bleeding complications related to triple antithrombotic therapy usage in patients with atrial fibrillation undergoing percutaneous coronary artery stenting. Chest. 2008 Sep;134(3):559-67. doi: 10.1378/chest.08-0350. Epub 2008 Jul 18. PubMed PMID: 18641090. 592: Pineda J, Marín F, Marco P, Roldán V, Valencia J, Ruiz-Nodar JM, Sogorb F, Lip GY. Premature coronary artery disease in young (age <45) subjects: interactions of lipid profile, thrombophilic and haemostatic markers. Int J Cardiol. 2009 Aug 14;136(2):222-5. doi: 10.1016/j.ijcard.2008.04.020. Epub 2008 Jul 14. PubMed PMID: 18625524. 593: Chung I, Choudhury A, Patel J, Lip GY. Soluble, platelet-bound, and total P-selectin as indices of platelet activation in congestive heart failure. Ann Med. 2009;41(1):45-51. doi: 10.1080/07853890802227089. PubMed PMID: 18618353. 594: Lip GY. Paroxysmal atrial fibrillation, stroke risk and thromboprophylaxis. Thromb Haemost. 2008 Jul;100(1):11-3. doi: 10.1160/TH08-05-0331. PubMed PMID: 18612530. 82 595: Shantsila E, Lip GY. Beyond glucose levels in diabetic patients with coronary artery disease: platelet activity and non-responsiveness to antiplatelet therapy. Thromb Haemost. 2008 Jul;100(1):7-8. doi: 10.1160/TH08-06-0342. PubMed PMID: 18612528. 596: Preissner KT, Lip GY. Thrombosis and Haemostasis: volume 100 and going strong ... Thromb Haemost. 2008 Jul;100(1):1-2. doi: 10.1160/TH08-06-0359. PubMed PMID: 18612525. 597: Lim SH, Lip GY, Sanderson JE. Ventricular optimization of biventricular pacing: a systematic review. Europace. 2008 Aug;10(8):901-6. doi: 10.1093/europace/eun177. Epub 2008 Jul 8. Review. PubMed PMID: 18611967. 598: Rubboli A, Halperin JL, Airaksinen KE, Buerke M, Eeckhout E, Freedman SB, Gershlick AH, Schlitt A, Tse HF, Verheugt FW, Lip GY. Antithrombotic therapy in patients treated with oral anticoagulation undergoing coronary artery stenting. An expert consensus document with focus on atrial fibrillation. Ann Med. 2008;40(6):428-36. doi: 10.1080/07853890802089786. Review. PubMed PMID: 18608125. 599: Roldán V, Marín F, González-Conejero R, García-Honrubia A, Martí S, Alfaro A, Valdés M, Corral J, Lip GY, Vicente V. Factor VII -323 decanucleotide D/I polymorphism in atrial fibrillation: implications for the prothrombotic state and stroke risk. Ann Med. 2008;40(7):553-9. doi: 10.1080/07853890802108412. PubMed PMID: 18608122. 600: Lip GY. Risk factors and stroke risk stratification for atrial fibrillation: limitations and new possibilities. Am Heart J. 2008 Jul;156(1):1-3. doi: 10.1016/j.ahj.2008.02.020. Epub 2008 May 5. PubMed PMID: 18585489. 601: Bennett PC, Lane DA, Lip GY. Vital exhaustion and cardiovascular disease: are circulating fibrinogen and D-dimer levels a plausible link? Stress. 2008 Jul;11(4):247-9. doi: 10.1080/10253890701833029. PubMed PMID: 18574785. 602: Lip GY, Blann AD. Endothelium and fibrinolysis in hypertension: important facets of a prothrombotic state? Hypertension. 2008 Aug;52(2):218-9. doi: 10.1161/HYPERTENSIONAHA.108.114876. Epub 2008 Jun 23. PubMed PMID: 18574069. 83 603: Gunarathne A, Patel JV, Hughes EA, Lip GY. Measurement of stiffness index by digital volume pulse analysis technique: clinical utility in cardiovascular disease risk stratification. Am J Hypertens. 2008 Aug;21(8):866-72. doi: 10.1038/ajh.2008.207. Epub 2008 Jun 12. PubMed PMID: 18551104. 604: Gunarathne A, Patel JV, Gammon B, Hughes EA, Lip GY. Impact of mean arterial blood pressure on higher arterial stiffness indices in South Asians compared to white Europeans. J Hypertens. 2008 Jul;26(7):1420-6. doi: 10.1097/HJH.0b013e3282ffb42a. PubMed PMID: 18551019. 605: Dwivedi G, Lip GY. The left atrium and diastolic dysfunction in hypertensive left ventricular hypertrophy: a consideration of size and function? J Hypertens. 2008 Jul;26(7):1310-2. doi: 10.1097/HJH.0b013e328302ee20. PubMed PMID: 18551004. 606: ADVANCE Collaborative Group, Patel A, MacMahon S, Chalmers J, Neal B, Billot L, Woodward M, Marre M, Cooper M, Glasziou P, Grobbee D, Hamet P, Harrap S, Heller S, Liu L, Mancia G, Mogensen CE, Pan C, Poulter N, Rodgers A, Williams B, Bompoint S, de Galan BE, Joshi R, Travert F. Intensive blood glucose control and vascular outcomes in patients with type 2 diabetes. N Engl J Med. 2008 Jun 12;358(24):2560-72. doi: 10.1056/NEJMoa0802987. Epub 2008 Jun 6. PubMed PMID: 18539916. 607: Melenovsky V, Lip GY. Interleukin-8 and atrial fibrillation. Europace. 2008 Jul;10(7):784-5. doi: 10.1093/europace/eun154. Epub 2008 Jun 3. PubMed PMID: 18523030. 608: Patel JV, Dwivedi S, Hughes EA, Lip GY. Premature coronary artery disease: an inferred cardiovascular variant or a South Asian genetic disorder? Thromb Haemost. 2008 Jun;99(6):991-2. doi: 10.1160/TH08-05-0286. PubMed PMID: 18521497. 609: Lim HS, Lip GY. Arterial stiffness: beyond pulse wave velocity and its measurement. J Hum Hypertens. 2008 Oct;22(10):656-8. doi: 10.1038/jhh.2008.47. PubMed PMID: 18509344. 610: Lip GY, Boos CJ. Antithrombotic treatment in atrial fibrillation. Postgrad Med J. 2008 May;84(991):252-8. doi: 10.1136/hrt.2005.066944. Review. PubMed PMID: 18508982. 84 611: Tardif JC, McMurray JJ, Klug E, Small R, Schumi J, Choi J, Cooper J, Scott R, Lewis EF, L'Allier PL, Pfeffer MA; Aggressive Reduction of Inflammation Stops Events (ARISE) Trial Investigators. Effects of succinobucol (AGI-1067) after an acute coronary syndrome: a randomised, double-blind, placebo-controlled trial. Lancet. 2008 May 24;371(9626):1761-8. doi: 10.1016/S0140-6736(08)60763-1. PubMed PMID: 18502300. 612: Bhatia GS, Sosin MD, Patel JV, Grindulis KA, Khattak FH, Davis RC, Lip GY. Plasma indices of endothelial and platelet activation in Rheumatoid Disease: relationship to cardiovascular co-morbidity. Int J Cardiol. 2009 May 1;134(1):97-103. doi: 10.1016/j.ijcard.2008.01.038. Epub 2008 May 23. PubMed PMID: 18501982. 613: Shantsila E, Watson T, Lip GY. Statins and inflammation: reciprocal effectors to endothelial progenitors? Thromb Res. 2008;123(1):1-4. doi: 10.1016/j.thromres.2008.03.021. Epub 2008 May 15. PubMed PMID: 18485454. 614: Lim HS, Lip GY. Asymptomatic atrial fibrillation on device interrogation. J Cardiovasc Electrophysiol. 2008 Aug;19(8):891-3. doi: 10.1111/j.1540-8167.2008.01194.x. Epub 2008 May 9. Review. PubMed PMID: 18479327. 615: Lim HS, Lip GY. Circulating matrix metalloproteinase-9 levels in atherosclerotic vascular disease: a possible measurement of systemic or specific disease pathophysiology? J Intern Med. 2008 Jun;263(6):620-2. doi: 10.1111/j.1365-2796.2008.01937.x. Review. PubMed PMID: 18479262. 616: Gasparyan AY, Watson T, Lip GY. The role of aspirin in cardiovascular prevention: implications of aspirin resistance. J Am Coll Cardiol. 2008 May 13;51(19):1829-43. doi: 10.1016/j.jacc.2007.11.080. Review. PubMed PMID: 18466797. 617: Williams RC, Barnett AH, Claffey N, Davis M, Gadsby R, Kellett M, Lip GY, Thackray S. The potential impact of periodontal disease on general health: a consensus view. Curr Med Res Opin. 2008 Jun;24(6):1635-43. doi: 10.1185/03007990802131215. Epub 2008 Apr 30. Review. PubMed PMID: 18452645. 618: Blanc JJ, Almendral J, Brignole M, Fatemi M, Gjesdal K, González-Torrecilla E, Kulakowski P, Lip GY, Shah D, Wolpert C; Scientific Initiatives Committee of the European Heart Rhythm Association. Consensus document on antithrombotic 85 therapy in the setting of electrophysiological procedures. Europace. 2008 May;10(5):513-27. doi: 10.1093/europace/eun104. PubMed PMID: 18442963. 619: Shantsila E, Lip GY. Circulating endothelial cells in health and disease: how do we best quantify them? J Thromb Haemost. 2008 Jun;6(6):1021-4. doi: 10.1111/j.1538-7836.2008.02985.x. Epub 2008 Apr 18. PubMed PMID: 18429943. 620: Stroke Risk in Atrial Fibrillation Working Group. Comparison of 12 risk stratification schemes to predict stroke in patients with nonvalvular atrial fibrillation. Stroke. 2008 Jun;39(6):1901-10. doi: 10.1161/STROKEAHA.107.501825. Epub 2008 Apr 17. Review. PubMed PMID: 18420954. 621: Taggar JS, Lip GY. Anticoagulation in atrial fibrillation: the trials and tribulations of keeping within therapeutic range. Curr Med Res Opin. 2008 May;24(5):1455-8. doi: 10.1185/030079908X301875 . Epub 2008 Apr 9. PubMed PMID: 18402716. 622: Dwivedi G, Khair O, Lip GY. Obstructive sleep apnoea and metabolic syndrome: two sides of the same coin? J Hum Hypertens. 2008 Jun;22(6):377-9. doi: 10.1038/jhh.2008.14. Epub 2008 Apr 3. PubMed PMID: 18385745. 623: Patel JV, Lim HS, Varughese GI, Hughes EA, Lip GY. Angiopoietin-2 levels as a biomarker of cardiovascular risk in patients with hypertension. Ann Med. 2008;40(3):215-22. doi: 10.1080/07853890701779586. PubMed PMID: 18382887. 624: Lim HS, Lip GY, Tse HF. Implantable cardioverter defibrillator following acute myocardial infarction: the '48-hour' and '40-day' rule. Europace. 2008 May;10(5):536-9. doi: 10.1093/europace/eun070. Epub 2008 Mar 26. Review. PubMed PMID: 18367548. 625: Kakar P, Watson T, Lip GY. New approaches to therapy with omega-3 fatty acids. Curr Atheroscler Rep. 2008 Feb;10(1):79-87. Review. PubMed PMID: 18366989. 626: Blann AD, Lip GY. Plasma metalloproteinase-9 in age-related macular degeneration. Eye (Lond). 2009 Feb;23(2):494-5; author reply 495. doi: 10.1038/eye.2008.71. Epub 2008 Mar 21. PubMed PMID: 18356925. 86 627: Mahadevan G, Davis RC, Frenneaux MP, Hobbs FD, Lip GY, Sanderson JE, Davies MK. Left ventricular ejection fraction: are the revised cut-off points for defining systolic dysfunction sufficiently evidence based? Heart. 2008 Apr;94(4):426-8. doi: 10.1136/hrt.2007.123877. Review. PubMed PMID: 18347374. 628: Kistorp C, Chong AY, Gustafsson F, Galatius S, Raymond I, Faber J, Lip GY, Hildebrandt P. Biomarkers of endothelial dysfunction are elevated and related to prognosis in chronic heart failure patients with diabetes but not in those without diabetes. Eur J Heart Fail. 2008 Apr;10(4):380-7. doi: 10.1016/j.ejheart.2008.02.012. Epub 2008 Mar 17. PubMed PMID: 18343722. 629: Lip GY. Don't add aspirin for associated stable vascular disease in a patient with atrial fibrillation receiving anticoagulation. BMJ. 2008 Mar 15;336(7644):614-5. doi: 10.1136/bmj.39351.706586.AD. Review. PubMed PMID: 18340078; PubMed Central PMCID: PMC2267987. 630: Freestone B, Gustafsson F, Chong AY, Corell P, Kistorp C, Hildebrandt P, Lip GY. Influence of atrial fibrillation on plasma von willebrand factor, soluble E-selectin, and N-terminal pro B-type natriuretic peptide levels in systolic heart failure. Chest. 2008 May;133(5):1203-8. doi: 10.1378/chest.07-2557. Epub 2008 Mar 13. PubMed PMID: 18339785. 631: Nieuwlaat R, Dinh T, Olsson SB, Camm AJ, Capucci A, Tieleman RG, Lip GY, Crijns HJ; Euro Heart Survey Investigators. Should we abandon the common practice of withholding oral anticoagulation in paroxysmal atrial fibrillation? Eur Heart J. 2008 Apr;29(7):915-22. doi: 10.1093/eurheartj/ehn101. Epub 2008 Mar 10. PubMed PMID: 18334476. 632: Jolly K, Lip GY, Taylor RS, Raftery J, Mant J, Lane D, Greenfield S, Stevens A. The Birmingham Rehabilitation Uptake Maximisation study (BRUM): a randomised controlled trial comparing home-based with centre-based cardiac rehabilitation. Heart. 2009 Jan;95(1):36-42. doi: 10.1136/hrt.2007.127209. Epub 2008 Mar 10. PubMed PMID: 18332063. 633: Taggar JS, Marín F, Lip GY. Mortality in patients with atrial fibrillation: improving or not? Europace. 2008 Apr;10(4):389-90. doi: 10.1093/europace/eun054. Epub 2008 Mar 8. PubMed PMID: 18326851. 634: Grupa Robocza Europejskiego Towarzystwa Kardiologicznego ds. stymulacji 87 serca i resynchronizacji we współpracy; Europejskim Towarzystwem Rytmu Serca, Vardas PE, Auricchio A, Blanc JJ, Daubert JC, Drexler H, Ector H, Gasparini M, Linde C, Morgado FB, Oto A, Sutton R, Trusz-Gluza M, Vahanian A, Camm J, De Caterina R, Dean V, Dickstein K, Funck-Brentano C, Filippatos G, Hellemans I, Kristensen SD, McGregor K, Sechtem U, Silber S, Tendera M, Widimsky P, Zamorano JL, Priori SG, Blomström-Lundqvist C, Brignole M, Terradellas JB, Camm J, Castellano P, Cleland J, Farre J, Fromer M, Le Heuzey JY, Lip GY, Merino JL, Montenero AS, Ritter P, Schlij MJ, Stellbrink C; European Cardiac Society. [Guidelines in cardiac pacing and resynchronization therapy]. Kardiol Pol. 2007 Dec;65(12):1449-87; discussion 1488-9. Polish. PubMed PMID: 18326113. 635: Lip GY. The balance between stroke prevention and bleeding risk in atrial fibrillation: a delicate balance revisited. Stroke. 2008 May;39(5):1406-8. doi: 10.1161/STROKEAHA.107.506832. Epub 2008 Mar 6. PubMed PMID: 18323477. 636: Watson T, Goon PK, Lip GY. Endothelial progenitor cells, endothelial dysfunction, inflammation, and oxidative stress in hypertension. Antioxid Redox Signal. 2008 Jun;10(6):1079-88. doi: 10.1089/ars.2007.1998. Review. PubMed PMID: 18315493. 637: Roldán V, Marín F, Lip GY. Letter by Roldán et al regarding article, "Plasminogen activator inhibitor-1 as a predictor of postoperative atrial fibrillation after cardiopulmonary bypass". Circulation. 2008 Feb 26;117(8):e169; author reply e170. doi: 10.1161/CIRCULATIONAHA.107.746461. PubMed PMID: 18299509. 638: Ruiz-Nodar JM, Marín F, Hurtado JA, Valencia J, Pinar E, Pineda J, Gimeno JR, Sogorb F, Valdés M, Lip GY. Anticoagulant and antiplatelet therapy use in 426 patients with atrial fibrillation undergoing percutaneous coronary intervention and stent implantation implications for bleeding risk and prognosis. J Am Coll Cardiol. 2008 Feb 26;51(8):818-25. doi: 10.1016/j.jacc.2007.11.035. PubMed PMID: 18294566. 639: Boos CJ, Blann AD, Lip GY. Assessment of endothelial damage/dysfunction: a focus on circulating endothelial cells. Methods Mol Med. 2007;139:211-24. PubMed PMID: 18287674. 640: Hughes M, Lip GY; Guideline Development Group, National Clinical Guideline for Management of Atrial Fibrillation in Primary and Secondary Care, National Institute for Health and Clinical Excellence. Stroke and thromboembolism in atrial fibrillation: a systematic review of stroke risk factors, risk 88 stratification schema and cost effectiveness data. Thromb Haemost. 2008 Feb;99(2):295-304. doi: 10.1160/TH07-08-0508. Review. PubMed PMID: 18278178. 641: Lip GY, Frison L, Grind M; SPORTIF Investigators. Stroke event rates in anticoagulated patients with paroxysmal atrial fibrillation. J Intern Med. 2008 Jul;264(1):50-61. doi: 10.1111/j.1365-2796.2007.01909.x. Epub 2008 Feb 4. PubMed PMID: 18266660. 642: Shantsila E, Watson T, Tse HF, Lip GY. New insights on endothelial progenitor cell subpopulations and their angiogenic properties. J Am Coll Cardiol. 2008 Feb 12;51(6):669-71. doi: 10.1016/j.jacc.2007.09.057. PubMed PMID: 18261687. 643: Gohar F, Greenfield SM, Beevers DG, Lip GY, Jolly K. Self-care and adherence to medication: a survey in the hypertension outpatient clinic. BMC Complement Altern Med. 2008 Feb 8;8:4. doi: 10.1186/1472-6882-8-4. PubMed PMID: 18261219; PubMed Central PMCID: PMC2259297. 644: Chung I, Goyal D, Macfadyen RJ, Lip GY. The effects of maximal treadmill graded exercise testing on haemorheological, haemodynamic and flow cytometry platelet markers in patients with systolic or diastolic heart failure. Eur J Clin Invest. 2008 Mar;38(3):150-8. doi: 10.1111/j.1365-2362.2008.01909.x. PubMed PMID: 18257777. 645: Climent V, Marín F, Mainar L, Roldán V, García A, Martínez JG, Lip GY. Influence of electrical cardioversion on inflammation and indexes of structural remodeling, in persistent atrial fibrillation. Int J Cardiol. 2009 Feb 20;132(2):227-32. doi: 10.1016/j.ijcard.2007.11.044. Epub 2008 Jan 30. PubMed PMID: 18234374. 646: Thornhill K, Lyons AC, Nouwen A, Lip GY. Experiences of living with congestive heart failure: a qualitative study. Br J Health Psychol. 2008 Feb;13(Pt 1):155-75. doi: 10.1348/135910706X170983. PubMed PMID: 18230240. 647: Shantsila E, Blann AD, Lip GY. Circulating endothelial cells: from bench to clinical practice. J Thromb Haemost. 2008 May;6(5):865-8. doi: 10.1111/j.1538-7836.2008.02918.x. Epub 2008 Jan 25. Review. PubMed PMID: 18221356. 89 648: Tan KT, Lip GY. Imaging of the unstable plaque. Int J Cardiol. 2008 Jul 4;127(2):157-65. doi: 10.1016/j.ijcard.2007.11.054. Epub 2008 Jan 22. Review. PubMed PMID: 18207257. 649: Patel JV, Lim HS, Gunarathne A, Tracey I, Durrington PN, Hughes EA, Lip GY. Ethnic differences in myocardial infarction in patients with hypertension: effects of diabetes mellitus. QJM. 2008 Mar;101(3):231-6. doi: 10.1093/qjmed/hcm151. Epub 2008 Jan 19. PubMed PMID: 18204065. 650: Taggar JS, Lip GY. Risk predictors for lone atrial fibrillation. Europace. 2008 Jan;10(1):6-8. doi: 10.1093/europace/eum274. PubMed PMID: 18199571. 651: Boos CJ, Lip GY. Inflammation and atrial fibrillation: cause or effect? Heart. 2008 Feb;94(2):133-4. doi: 10.1136/hrt.2007.119651. PubMed PMID: 18195117. 652: Goon PK, Watson T, Stonelake PS, Lip GY. Endothelial progenitor cells: from pathophysiology to clinical practice. Int J Clin Pract. 2008 Jan;62(1):4-6. doi: 10.1111/j.1742-1241.2007.01555.x. PubMed PMID: 18173810. 653: Taggar JS, Lip GY. The QRISK was less likely to overestimate cardiovascular risk than the Framingham or ASSIGN equations. ACP J Club. 2008 Jan-Feb;148(1):25. PubMed PMID: 18171012. 654: Boos CJ, Lane DA, Lip GY. Atrial fibrillation (chronic). Clin Evid (Online). 2008 Apr 30;2008. doi:pii: 0217. PubMed PMID: 19450316; PubMed Central PMCID: PMC2907948. 655: Lip GY, Watson T. Atrial fibrillation (acute onset). Clin Evid (Online). 2008 May 2;2008. doi:pii: 0210. PubMed PMID: 19450312; PubMed Central PMCID: PMC2907989. 656: Lip GY, Kalra L. Stroke prevention. Clin Evid (Online). 2008 Sep 3;2008. doi:pii: 0207. PubMed PMID: 19445804. 657: Taggar JS, Watson T, Lip GY. Can patients with atrial fibrillation be optimally risk stratified for stroke and thromboembolism? Stroke. 2008 90 Feb;39(2):e24-5; author reply e26. Epub 2007 Dec 27. PubMed PMID: 18162618. 658: Caine GJ, Lip G, Zanetto U, Maheshwari M, Stonelake PS, Blann AD. A comparison of plasma versus histologic indices of angiogenic markers in breast cancer. Appl Immunohistochem Mol Morphol. 2007 Dec;15(4):382-8. PubMed PMID: 18091379. 659: Dotsenko O, Chackathayil J, Lip GY. Measurement of C-reactive protein and natriuretic peptides for cardiovascular risk assessment: the need for age and gender-specific thresholds. J Hypertens. 2008 Jan;26(1):11-3. PubMed PMID: 18090533. 660: Chung I, Choudhury A, Patel J, Lip GY. Soluble CD40L, platelet surface CD40L and total platelet CD40L in congestive heart failure: relationship to platelet volume, mass and granularity. J Intern Med. 2008 Mar;263(3):313-21. Epub 2007 Dec 10. PubMed PMID: 18086125. 661: Blann AD, Mohan JS, Bareford D, Lip GY. Soluble P-selectin and vascular endothelial growth factor in steady state sickle cell disease: relationship to genotype. J Thromb Thrombolysis. 2008 Apr;25(2):185-9. Epub 2007 Dec 14. PubMed PMID: 18080800. 662: Boos CJ, Balakrishnan B, Jessani S, Blann AD, Lip GY. Effects of percutaneous coronary intervention on peripheral venous blood circulating endothelial cells and plasma indices of endothelial damage/dysfunction. Chest. 2007 Dec;132(6):1920-6. PubMed PMID: 18079225. 663: Choudhury A, Freestone B, Patel J, Lip GY. Relationship of soluble CD40 ligand to vascular endothelial growth factor, angiopoietins, and tissue factor in atrial fibrillation: a link among platelet activation, angiogenesis, and thrombosis? Chest. 2007 Dec;132(6):1913-9. PubMed PMID: 18079224. 664: Watson T, Lip GY. Identifying AF patients at risk of stroke: can prothrombotic indices improve things? Int J Cardiol. 2008 Jun 6;126(3):299-301. Epub 2008 Feb 20. PubMed PMID: 18077017. 665: Lip GY, Rudolf M; Guideline development group for the NICE clinical guideline for the management of atrial fibrillation. Atrial fibrillation: Rate 91 control and digoxin. BMJ. 2007 Dec 8;335(7631):1169-70. PubMed PMID: 18063614; PubMed Central PMCID: PMC2128644. 666: Lim HS, Tayebjee MH, Tan KT, Patel JV, Macfadyen RJ, Lip GY. Is soluble CD40 ligand a mediator of angiogenesis in patients with coronary artery disease? Thromb Res. 2008;122(3):307-13. Epub 2007 Dec 3. PubMed PMID: 18054068. 667: Lane DA, Lip GY. Barriers to anticoagulation in patients with atrial fibrillation: changing physician-related factors. Stroke. 2008 Jan;39(1):7-9. Epub 2007 Nov 29. PubMed PMID: 18048849. 668: Patel JV, Gunarathne A, Lane D, Lim HS, Tracey I, Panja NC, Lip GY, Hughes EA. Widening access to cardiovascular healthcare: community screening among ethnic minorities in inner-city Britain - the Healthy Hearts Project. BMC Health Serv Res. 2007 Nov 23;7:192. PubMed PMID: 18036225; PubMed Central PMCID: PMC2222625. 669: Gunarathne A, Patel JV, Potluri R, Gammon B, Jessani S, Hughes EA, Lip GY. Increased 5-year mortality in the migrant South Asian stroke patients with diabetes mellitus in the United Kingdom: the West Birmingham Stroke Project. Int J Clin Pract. 2008 Feb;62(2):197-201. Epub 2007 Nov 23. PubMed PMID: 18036165. 670: Dotsenko O, Chackathayil J, Lip GY. Cardiac biomarkers: myths, facts and future horizons. Expert Rev Mol Diagn. 2007 Nov;7(6):693-7. Review. PubMed PMID: 18020898. 671: Shantsila E, Watson T, Lip GY. Drug-induced QT-interval prolongation and proarrhythmic risk in the treatment of atrial arrhythmias. Europace. 2007 Sep;9 Suppl 4:iv37-44. Review. PubMed PMID: 17766322. 672: Boos CJ, Lane DA, Karpha M, Beevers DG, Haynes R, Lip GY. Circulating endothelial cells, arterial stiffness, and cardiovascular risk stratification in hypertension. Chest. 2007 Nov;132(5):1540-7. PubMed PMID: 17998358. 673: Freestone B, Chong AY, Nuttall S, Lip GY. Impaired flow mediated dilatation as evidence of endothelial dysfunction in chronic atrial fibrillation: relationship to plasma von Willebrand factor and soluble E-selectin levels. Thromb Res. 2008;122(1):85-90. Epub 2007 Nov 8. PubMed PMID: 17996280. 92 674: Tello-Montoliu A, Marín F, Roldán V, Mainar L, López MT, Sogorb F, Vicente V, Lip GY. A multimarker risk stratification approach to non-ST elevation acute coronary syndrome: implications of troponin T, CRP, NT pro-BNP and fibrin D-dimer levels. J Intern Med. 2007 Dec;262(6):651-8. Epub 2007 Nov 7. PubMed PMID: 17986200. 675: Tello-Montoliu A, Marín F, Patel J, Roldán V, Mainar L, Vicente V, Sogorb F, Lip GY. Plasma angiogenin levels in acute coronary syndromes: implications for prognosis. Eur Heart J. 2007 Dec;28(24):3006-11. Epub 2007 Nov 2. PubMed PMID: 17981827. 676: Lip GY. Post-stenting antithrombotic drug therapy in patients with atrial fibrillation. Am J Med. 2007 Nov;120(11):920-2. PubMed PMID: 17976413. 677: Shantsila E, Watson T, Lip GY. Cardioversion and remodelling in atrial fibrillation: Insights beyond the prothrombotic state. Thromb Res. 2008;121(4):443-5. Epub 2007 Oct 24. PubMed PMID: 17961637. 678: Lip GY, Lim HS. Atrial fibrillation and stroke prevention. Lancet Neurol. 2007 Nov;6(11):981-93. Review. PubMed PMID: 17945152. 679: Sharobeem KM, Patel JV, Ritch AE, Lip GY, Gill PS, Hughes EA. Elevated lipoprotein (a) and apolipoprotein B to AI ratio in South Asian patients with ischaemic stroke. Int J Clin Pract. 2007 Nov;61(11):1824-8. PubMed PMID: 17935546. 680: Srivastava S, Lip GY. Atherosclerotic renal artery stenosis--do we really know what to do? Blood Press. 2007;16(5):288-90. Review. PubMed PMID: 17934915. 681: Jaumdally RJ, Varma C, Blann AD, Macfadyen RJ, Lip GY. Indices of angiogenesis, platelet activation, and endothelial damage/dysfunction in relation to ethnicity and coronary artery disease: differences in central versus peripheral levels. Ann Med. 2007;39(8):628-33. PubMed PMID: 17934908. 682: Boos CJ, Balakrishnan B, Lip GY. The effects of exercise stress testing on soluble E-selectin, von Willebrand factor, and circulating endothelial cells as 93 indices of endothelial damage/dysfunction. Ann Med. 2008;40(1):66-73. PubMed PMID: 17934907. 683: Thrall G, Lane D, Carroll D, Lip GY. A systematic review of the prothrombotic effects of an acute change in posture: a possible mechanism underlying the morning excess in cardiovascular events? Chest. 2007 Oct;132(4):1337-47. Review. PubMed PMID: 17934119. 684: Grupo de Trabajo para el Tratamiento de la Hipertensión Arterial de la Sociedad Europea; Sociedad Europea de Cardiología, Mancia G, De Backer G, Dominiczak A, Cifkova R, Fagard R, Germano G, Grassi G, Heagerty AM, Kjeldsen SE, Laurent S, Narkiewicz K, Ruilope L, Rynkiewicz A, Schmieder RE, Boudier HA, Zanchetti A, Vahanian A, Camm J, De Caterina R, Dean V, Dickstein K, Filippatos G, Funck-Brentano C, Hellemans I, Kristensen SD, McGregor K, Sechtem U, Silber S, Tendera M, Widimsky P, Zamorano JL, Erdine S, Kiowski W, Agabiti-Rosei E, Ambrosion E, Fagard R, Lindholm LH, Manolis A, Nilsson PM, Redon J, Viigimaa M, Adamopoulos S, Agabiti-Rosei E, Bertomeu V, Clement D, Farsang C, Gaita D, Lip G, Mallion JM, Manolis AJ, Nilsson PM, O'Brien E, Ponikowski P, Ruschitzka F, Tamargo J, van Zwieten P, Viigimaa M, Waeber B, Williams B, Zamorano JL. [ESH/ESC 2007 Guidelines for the management of arterial hypertension]. Rev Esp Cardiol. 2007 Sep;60(9):968.e1-94. Review. Spanish. PubMed PMID: 17915153. 685: Jaumdally RJ, Varma C, Blann AD, MacFadyen RJ, Lip GY. Platelet activation in coronary artery disease: intracardiac vs peripheral venous levels and the effects of angioplasty. Chest. 2007 Nov;132(5):1532-9. Epub 2007 Oct 1. PubMed PMID: 17908707. 686: Taggar JS, Lip GY. Anticoagulation for elderly patients with atrial fibrillation: not to be neglected. Europace. 2008 Jan;10(1):1-2. Epub 2007 Sep 28. PubMed PMID: 17906285. 687: Chuen MJ, Lip GY, MacFadyen RJ. Repeated assessment of physical biomeasures or blood biomarkers for the definition of volume status and cardiac loading in LVSD. Biomark Med. 2007 Oct;1(3):355-74. doi: 10.2217/17520363.1.3.355. PubMed PMID: 20477380. 688: Kirchhof P, Auricchio A, Bax J, Crijns H, Camm J, Diener HC, Goette A, Hindricks G, Hohnloser S, Kappenberger L, Kuck KH, Lip GY, Olsson B, Meinertz T, Priori S, Ravens U, Steinbeck G, Svernhage E, Tijssen J, Vincent A, Breithardt G. Outcome parameters for trials in atrial fibrillation: recommendations from a 94 consensus conference organized by the German Atrial Fibrillation Competence NETwork and the European Heart Rhythm Association. Europace. 2007 Nov;9(11):1006-23. Epub 2007 Sep 25. PubMed PMID: 17897925. 689: Kirchhof P, Auricchio A, Bax J, Crijns H, Camm J, Diener HC, Goette A, Hindricks G, Hohnloser S, Kappenberger L, Kuck KH, Lip GY, Olsson B, Meinertz T, Priori S, Ravens U, Steinbeck G, Svernhage E, Tijssen J, Vincent A, Breithardt G. Outcome parameters for trials in atrial fibrillation: executive summary. Eur Heart J. 2007 Nov;28(22):2803-17. Epub 2007 Sep 25. PubMed PMID: 17897924. 690: Lim HS, Lip GY. From diabetes to metabolic syndrome: a viewpoint on an evolving concept. Curr Pharm Des. 2007;13(25):2580-3. Review. PubMed PMID: 17897002. 691: Karthikeyan VJ, Lip GY. Hypertension in pregnancy: pathophysiology and management strategies. Curr Pharm Des. 2007;13(25):2567-79. Review. PubMed PMID: 17897001. 692: Kühl M, Lip GY, Varma C. Management of hypertension in relation to acute coronary syndromes and revascularisation. Curr Pharm Des. 2007;13(25):2556-66. Review. PubMed PMID: 17897000. 693: Goon PK, Stonelake PS, Lip GY. Hypertension, anti-hypertensive therapy and neoplasia. Curr Pharm Des. 2007;13(25):2539-44. Review. PubMed PMID: 17896998. 694: Hamaad A, Lip GY, Nicholls D, MacFadyen RJ. Comparative dose titration responses to the introduction of bisoprolol or carvedilol in stable chronic systolic heart failure. Cardiovasc Drugs Ther. 2007 Dec;21(6):437-44. PubMed PMID: 17896170. 695: Freestone B, Chong AY, Nuttall S, Blann AD, Lip GY. Soluble E-selectin, von Willebrand factor, soluble thrombomodulin, and total body nitrate/nitrite product as indices of endothelial damage/dysfunction in paroxysmal, persistent, and permanent atrial fibrillation. Chest. 2007 Oct;132(4):1253-8. Epub 2007 Sep 21. PubMed PMID: 17890461. 696: Shantsila E, Watson T, Tse HF, Lip GY. Endothelial colony forming units: are they a reliable marker of endothelial progenitor cell numbers? Ann Med. 95 2007;39(6):474-9. PubMed PMID: 17886173. 697: Chung I, Choudhury A, Lip GY. Platelet adhesion in congestive heart failure. Thromb Res. 2008;121(6):885-8. Epub 2007 Sep 17. PubMed PMID: 17870148. 698: Hughes M, Lip GY; Guideline Development Group for the NICE national clinical guideline for management of atrial fibrillation in primary and secondary care. Risk factors for anticoagulation-related bleeding complications in patients with atrial fibrillation: a systematic review. QJM. 2007 Oct;100(10):599-607. Epub 2007 Sep 10. Review. PubMed PMID: 17846060. 699: Boos CJ, Lip GY, Jilma B. Endotoxemia, inflammation, and atrial fibrillation. Am J Cardiol. 2007 Sep 15;100(6):986-8. Epub 2007 Jul 2. PubMed PMID: 17826383. 700: Jolly K, Taylor R, Lip GY, Greenfield S, Raftery J, Mant J, Lane D, Jones M, Lee KW, Stevens A. The Birmingham Rehabilitation Uptake Maximisation Study (BRUM). Home-based compared with hospital-based cardiac rehabilitation in a multi-ethnic population: cost-effectiveness and patient adherence. Health Technol Assess. 2007 Sep;11(35):1-118. Review. PubMed PMID: 17767899. 701: Karthikeyan VJ, Lip GY. Alpha 1-microglobulin: a further insight into inflammation in hypertension? Am J Hypertens. 2007 Sep;20(9):1022-3. PubMed PMID: 17765146. 702: Vardas PE, Auricchio A, Blanc JJ, Daubert JC, Drexler H, Ector H, Gasparini M, Linde C, Morgado FB, Oto A, Sutton R, Trusz-Gluza M; European Society of Cardiology; European Heart Rhythm Association. Guidelines for cardiac pacing and cardiac resynchronization therapy: The Task Force for Cardiac Pacing and Cardiac Resynchronization Therapy of the European Society of Cardiology. Developed in collaboration with the European Heart Rhythm Association. Eur Heart J. 2007 Sep;28(18):2256-95. Epub 2007 Aug 28. PubMed PMID: 17726042. 703: Sosin MD, Patel JV, Bhatia GS, Hughes EA, Davis RC, Lip GY. Effects of white European, African Caribbean and South Asian ethnicity on homocysteine levels in patients with systolic heart failure. Int J Cardiol. 2008 Sep 16;129(1):69-75. Epub 2007 Aug 23. PubMed PMID: 17719103. 96 704: Watson T, Lip GY. Combining antiplatelet drugs and oral anticoagulant therapy in atrial fibrillation: acute coronary syndromes and/or percutaneous coronary intervention/stenting revisited. Stroke. 2007 Oct;38(10):e107-8. Epub 2007 Aug 23. PubMed PMID: 17717305. 705: Lip GY, Tse HF. Management of atrial fibrillation. Lancet. 2007 Aug 18;370(9587):604-18. Review. PubMed PMID: 17707756. 706: Goon PK, Lip GY. Endothelial progenitor cells, endothelial cell dysfunction and much more: observations from cardiac syndrome X. Heart. 2007 Sep;93(9):1020-1. PubMed PMID: 17699169; PubMed Central PMCID: PMC1955028. 707: Jordán A, Roldán V, García M, Monmeneu J, de Burgos FG, Lip GY, Marín F. Matrix metalloproteinase-1 and its inhibitor, TIMP-1, in systolic heart failure: relation to functional data and prognosis. J Intern Med. 2007 Sep;262(3):385-92. PubMed PMID: 17697160. 708: Mant J, Hobbs FD, Fletcher K, Roalfe A, Fitzmaurice D, Lip GY, Murray E; BAFTA investigators; Midland Research Practices Network (MidReC). Warfarin versus aspirin for stroke prevention in an elderly community population with atrial fibrillation (the Birmingham Atrial Fibrillation Treatment of the Aged Study, BAFTA): a randomised controlled trial. Lancet. 2007 Aug 11;370(9586):493-503. PubMed PMID: 17693178. 709: Tello-Montoliu A, Moltó JM, López-Hernández N, García-Medina A, Roldán V, Sogorb F, Lip GY, Marín F. Common carotid artery intima-media thickness and intracranial pulsatility index in non-ST-elevation acute coronary syndromes. Cerebrovasc Dis. 2007;24(4):338-42. Epub 2007 Aug 9. PubMed PMID: 17690545. 710: Gunarathne A, Patel JV, Potluri R, Gill PS, Hughes EA, Lip GY. Secular trends in the cardiovascular risk profile and mortality of stroke admissions in an inner city, multiethnic population in the United Kingdom (1997-2005). J Hum Hypertens. 2008 Jan;22(1):18-23. Epub 2007 Aug 2. PubMed PMID: 17673899. 711: Fitzmaurice DA, Hobbs FD, Jowett S, Mant J, Murray ET, Holder R, Raftery JP, Bryan S, Davies M, Lip GY, Allan TF. Screening versus routine practice in detection of atrial fibrillation in patients aged 65 or over: cluster randomised controlled trial. BMJ. 2007 Aug 25;335(7616):383. Epub 2007 Aug 2. PubMed PMID: 17673732; PubMed Central PMCID: PMC1952508. 97 712: Thrall G, Lip GY, Carroll D, Lane D. Depression, anxiety, and quality of life in patients with atrial fibrillation. Chest. 2007 Oct;132(4):1259-64. Epub 2007 Jul 23. PubMed PMID: 17646231. 713: Jones M, Jolly K, Raftery J, Lip GY, Greenfield S; BRUM Steering Committee. 'DNA' may not mean 'did not participate': a qualitative study of reasons for non-adherence at home- and centre-based cardiac rehabilitation. Fam Pract. 2007 Sep;24(4):343-57. Epub 2007 Jul 13. PubMed PMID: 17630271. 714: Lip GY. Coronary artery disease and ischemic stroke in atrial fibrillation. Chest. 2007 Jul;132(1):8-10. PubMed PMID: 17625079. 715: Jessani S, Lip GY. Measuring soluble CD40 ligand:interleukin-10 ratio as a prognostic marker in acute myocardial infarction: yet another prognostic biomarker? Thromb Res. 2007;121(3):289-91. Epub 2007 Jul 3. Review. PubMed PMID: 17610938. 716: Goon PK, Watson T, Lip GY. New frontiers in cardiovascular disease: circulating endothelial cells and endothelial progenitor cells as cellular biomarkers. Clin Lab. 2007;53(5-6):297-9. PubMed PMID: 17605404. 717: Mant J, Fitzmaurice DA, Hobbs FD, Jowett S, Murray ET, Holder R, Davies M, Lip GY. Accuracy of diagnosing atrial fibrillation on electrocardiogram by primary care practitioners and interpretative diagnostic software: analysis of data from screening for atrial fibrillation in the elderly (SAFE) trial. BMJ. 2007 Aug 25;335(7616):380. Epub 2007 Jun 29. PubMed PMID: 17604299; PubMed Central PMCID: PMC1952490. 718: Kakar P, Boos CJ, Lip GY. Management of atrial fibrillation. Vasc Health Risk Manag. 2007;3(1):109-16. Review. PubMed PMID: 17583181; PubMed Central PMCID: PMC1994040. 719: Lim HS, Lip GY. Thromboprophylaxis in acute ischaemic stroke: how can we PREVAIL? Lancet Neurol. 2007 Jul;6(7):578-9. PubMed PMID: 17582355. 720: Lip GY, Watson T. Stroke prevention in atrial fibrillation--things can only 98 get better. Br J Clin Pharmacol. 2007 Nov;64(5):575-7. Epub 2007 Jun 19. PubMed PMID: 17578482; PubMed Central PMCID: PMC2203274. 721: Boos CJ, Balakrishnan B, Lip GY. The effects of coronary artery disease severity on time-dependent changes in platelet activation indices in stored whole blood. J Thromb Thrombolysis. 2008 Apr;25(2):135-40. Epub 2007 Jun 16. PubMed PMID: 17574521. 722: Lane DA, Lip GY, Beevers DG. Ethnic differences in cancer incidence and mortality: the Birmingham Factory Screening Project. QJM. 2007 Jul;100(7):423-31. Epub 2007 Jun 12. PubMed PMID: 17566012. 723: Mancia G, De Backer G, Dominiczak A, Cifkova R, Fagard R, Germano G, Grassi G, Heagerty AM, Kjeldsen SE, Laurent S, Narkiewicz K, Ruilope L, Rynkiewicz A, Schmieder RE, Boudier HA, Zanchetti A, Vahanian A, Camm J, De Caterina R, Dean V, Dickstein K, Filippatos G, Funck-Brentano C, Hellemans I, Kristensen SD, McGregor K, Sechtem U, Silber S, Tendera M, Widimsky P, Zamorano JL, Erdine S, Kiowski W, Agabiti-Rosei E, Ambrosioni E, Lindholm LH, Viigimaa M, Adamopoulos S, Agabiti-Rosei E, Ambrosioni E, Bertomeu V, Clement D, Erdine S, Farsang C, Gaita D, Lip G, Mallion JM, Manolis AJ, Nilsson PM, O'Brien E, Ponikowski P, Redon J, Ruschitzka F, Tamargo J, van Zwieten P, Waeber B, Williams B; Management of Arterial Hypertension of the European Society of Hypertension; European Society of Cardiology. 2007 Guidelines for the Management of Arterial Hypertension: The Task Force for the Management of Arterial Hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC). J Hypertens. 2007 Jun;25(6):1105-87. Erratum in: J Hypertens. 2007 Aug;25(8):1749. PubMed PMID: 17563527. 724: Jaumdally JR, Varma C, Lip GY. Statin therapy in South-Asian patients: clinical implications beyond lipid lowering? Expert Opin Pharmacother. 2007 Jun;8(9):1235-43. Review. PubMed PMID: 17563259. 725: Mancia G, De Backer G, Dominiczak A, Cifkova R, Fagard R, Germano G, Grassi G, Heagerty AM, Kjeldsen SE, Laurent S, Narkiewicz K, Ruilope L, Rynkiewicz A, Schmieder RE, Struijker Boudier HA, Zanchetti A, Vahanian A, Camm J, De Caterina R, Dean V, Dickstein K, Filippatos G, Funck-Brentano C, Hellemans I, Kristensen SD, McGregor K, Sechtem U, Silber S, Tendera M, Widimsky P, Zamorano JL, Kjeldsen SE, Erdine S, Narkiewicz K, Kiowski W, Agabiti-Rosei E, Ambrosioni E, Cifkova R, Dominiczak A, Fagard R, Heagerty AM, Laurent S, Lindholm LH, Mancia G, Manolis A, Nilsson PM, Redon J, Schmieder RE, Struijker-Boudier HA, Viigimaa M, Filippatos G, Adamopoulos S, Agabiti-Rosei E, Ambrosioni E, Bertomeu V, Clement D, Erdine S, 99 Farsang C, Gaita D, Kiowski W, Lip G, Mallion JM, Manolis AJ, Nilsson PM, O'Brien E, Ponikowski P, Redon J, Ruschitzka F, Tamargo J, van Zwieten P, Viigimaa M, Waeber B, Williams B, Zamorano JL, The task force for the management of arterial hypertension of the European Society of Hypertension, The task force for the management of arterial hypertension of the European Society of Cardiology. 2007 Guidelines for the management of arterial hypertension: The Task Force for the Management of Arterial Hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC). Eur Heart J. 2007 Jun;28(12):1462-536. Epub 2007 Jun 11. PubMed PMID: 17562668. 726: Jaumdally RJ, Varma C, Blann AD, MacFadyen RJ, Lip GY. Systemic and intracardiac vascular endothelial growth factor and angiopoietin-1 and -2 levels in coronary artery disease: effects of angioplasty. Ann Med. 2007;39(4):298-305. PubMed PMID: 17558601. 727: Blann AD, Choudhury A, Freestone B, Patel J, Lip GY. Soluble CD40 ligand and atrial fibrillation: relationship to platelet activation, and endothelial damage/dysfunction. Int J Cardiol. 2008 Jun 23;127(1):135-7. Epub 2007 Jun 6. PubMed PMID: 17555832. 728: Goon PK, Watson T, Stonelake PS, Lip GY. The quest for circulating endothelial cell standardization: the peril of platelets. Cytometry B Clin Cytom. 2007 Sep;72(5):416. PubMed PMID: 17549739. 729: Lip GY, Frison L, Grind M. Angiotensin converting enzyme inhibitor and angiotensin receptor blockade use in relation to outcomes in anticoagulated patients with atrial fibrillation. J Intern Med. 2007 Jun;261(6):577-86. PubMed PMID: 17547713. 730: Goon PK, Watson T, Lip GY. Circulating endothelial cells in obstructive sleep apnea: an important methodological lesson. Am J Respir Crit Care Med. 2007 Jun 15;175(12):1346; author reply 1347. PubMed PMID: 17545459. 731: Nieuwlaat R, Olsson SB, Lip GY, Camm AJ, Breithardt G, Capucci A, Meeder JG, Prins MH, Lévy S, Crijns HJ; Euro Heart Survey Investigators. Guideline-adherent antithrombotic treatment is associated with improved outcomes compared with undertreatment in high-risk patients with atrial fibrillation. The Euro Heart Survey on Atrial Fibrillation. Am Heart J. 2007 Jun;153(6):1006-12. PubMed PMID: 17540203. 100 732: Fletcher K, Mant J, Holder R, Fitzmaurice D, Lip GY, Hobbs FD. An analysis of factors that predict patient consent to take part in a randomized controlled trial. Fam Pract. 2007 Sep;24(4):388-94. Epub 2007 May 29. PubMed PMID: 17535839. 733: Spencer CG, Felmeden DC, Blann AD, Lip GY. Effects of "newer" and "older" antihypertensive drugs on hemorrheological, platelet, and endothelial factors. A substudy of the Anglo-Scandinavian Cardiac Outcomes Trial. Am J Hypertens. 2007 Jun;20(6):699-704. PubMed PMID: 17531931. 734: Jessani S, Lip GY. Physical fitness and the relationship between hypertension and markers of atherothrombosis. Am J Hypertens. 2007 Jun;20(6):676-7. PubMed PMID: 17531927. 735: Watson T, Kakar P, Lip GY. Cardioversion for atrial fibrillation: does inflammation matter? Am J Cardiol. 2007 Jun 1;99(11):1617-8. Epub 2007 Apr 17. PubMed PMID: 17531593. 736: Karthikeyan VJ, Lip GY. Peripheral artery disease and hypertension: the relation between ankle-brachial index and mortality. J Hum Hypertens. 2007 Oct;21(10):762-5. Epub 2007 May 17. PubMed PMID: 17508016. 737: Choudhury A, Chung I, Blann AD, Lip GY. Platelet surface CD62P and CD63, mean platelet volume, and soluble/platelet P-selectin as indexes of platelet function in atrial fibrillation: a comparison of "healthy control subjects" and "disease control subjects" in sinus rhythm. J Am Coll Cardiol. 2007 May 15;49(19):1957-64. Epub 2007 Apr 30. PubMed PMID: 17498581. 738: Lane DA, Lip GY. Maintaining therapeutic anticoagulation: the importance of keeping "within range". Chest. 2007 May;131(5):1277-9. PubMed PMID: 17494777. 739: Lip GY. Cardioversion of atrial fibrillation: from guidelines to contemporary clinical practice. Int J Clin Pract. 2007 May;61(5):714-6. PubMed PMID: 17493082. 740: Kakar P, Lip GY. Hypertension: endothelial dysfunction, the prothrombotic state and antithrombotic therapy. Expert Rev Cardiovasc Ther. 2007 May;5(3):441-50. Review. PubMed PMID: 17489669. 101 741: Goon PK, Lip GY. Involvement of circulating endothelial progenitor cells and vasculogenic factors in the pathogenesis of diabetic retinopathy. Eye (Lond). 2007 Jun;21(6):838-9; author reply 838. Epub 2007 Apr 20. PubMed PMID: 17464310. 742: Boos CJ, Soor SK, Kang D, Lip GY. Relationship between circulating endothelial cells and the predicted risk of cardiovascular events in acute coronary syndromes. Eur Heart J. 2007 May;28(9):1092-101. Epub 2007 Apr 21. PubMed PMID: 17449878. 743: Lip GY, Agnelli G, Thach AA, Knight E, Rost D, Tangelder MJ. Oral anticoagulation in atrial fibrillation: A pan-European patient survey. Eur J Intern Med. 2007 May;18(3):202-8. PubMed PMID: 17449392. 744: Lip GY, Kakar P, Watson T. Atrial fibrillation--the growing epidemic. Heart. 2007 May;93(5):542-3. PubMed PMID: 17435064; PubMed Central PMCID: PMC1955544. 745: Lip GY, Watson T. Stroke prevention in atrial fibrillation: antiplatelet therapy revisited. Eur Heart J. 2007 Apr;28(8):926-8. Epub 2007 Apr 12. PubMed PMID: 17430998. 746: Jolly K, Taylor RS, Lip GY, Singh S; BRUM Steering Committee. Reproducibility and safety of the incremental shuttle walking test for cardiac rehabilitation. Int J Cardiol. 2008 Mar 28;125(1):144-5. Epub 2007 Apr 3. PubMed PMID: 17408777. 747: Kakar P, Watson T, Lip GY. Drug evaluation: rivaroxaban, an oral, direct inhibitor of activated factor X. Curr Opin Investig Drugs. 2007 Mar;8(3):256-65. Review. PubMed PMID: 17408122. 748: Goon PK, Watson T, Shantsila E, Boos CJ, Lip GY. Standardization of circulating endothelial cell enumeration by the use of human umbilical vein endothelial cells. J Thromb Haemost. 2007 Apr;5(4):870-2. PubMed PMID: 17403205. 749: Jaumdally R, Varma C, Macfadyen RJ, Lip GY. Coronary sinus blood sampling: an insight into local cardiac pathophysiology and treatment? Eur Heart J. 2007 Apr;28(8):929-40. Epub 2007 Mar 29. Review. PubMed PMID: 17395678. 102 750: Jessani S, Gangopadhyay K, Patel JV, Lip GY, Millane T. Should oral glucose tolerance testing be mandatory following acute myocardial infarction? Int J Clin Pract. 2007 Apr;61(4):680-3. PubMed PMID: 17394440. 751: Varughese GI, Patel JV, Tomson J, Blann AD, Hughes EA, Lip GY. Prognostic value of plasma soluble P-selectin and von Willebrand factor as indices of platelet activation and endothelial damage/dysfunction in high-risk patients with hypertension: a sub-study of the Anglo-Scandinavian Cardiac Outcomes Trial. J Intern Med. 2007 Apr;261(4):384-91. PubMed PMID: 17391113. 752: Kakar P, Watson T, Lip GY. Rivaroxaban. Drugs Today (Barc). 2007 Mar;43(3):129-36. Review. PubMed PMID: 17380210. 753: Boos CJ, Beevers GD, Lip GY. Assessment of platelet activation indices using the ADVIATM 120 amongst 'high-risk' patients with hypertension. Ann Med. 2007;39(1):72-8. PubMed PMID: 17364453. 754: Choudhury A, Chung I, Blann AD, Lip GY. Elevated platelet microparticle levels in nonvalvular atrial fibrillation: relationship to p-selectin and antithrombotic therapy. Chest. 2007 Mar;131(3):809-15. PubMed PMID: 17356097. 755: Karthikeyan VJ, Beevers DG, Lip GY. Ethnic disparities in malignant hypertension: further observations. J Hypertens. 2007 Apr;25(4):895; author reply 896. PubMed PMID: 17351385. 756: Watson T, Shanstila E, Lip GY. Modern management of atrial fibrillation. Clin Med. 2007 Jan-Feb;7(1):28-34. Review. PubMed PMID: 17348571. 757: Jolly K, Tayor RS, Lip GY, Greenfield SM, Davies MK, Davis RC, Mant JW, Singh SJ, Ingram JT, Stubley J, Stevens AJ. Home-based exercise rehabilitation in addition to specialist heart failure nurse care: design, rationale and recruitment to the Birmingham Rehabilitation Uptake Maximisation study for patients with congestive heart failure (BRUM-CHF): a randomised controlled trial. BMC Cardiovasc Disord. 2007 Mar 7;7:9. PubMed PMID: 17343738; PubMed Central PMCID: PMC1821338. 103 758: Lip GY, Patel JV, Hughes E, Hart RG. High-sensitivity C-reactive protein and soluble CD40 ligand as indices of inflammation and platelet activation in 880 patients with nonvalvular atrial fibrillation: relationship to stroke risk factors, stroke risk stratification schema, and prognosis. Stroke. 2007 Apr;38(4):1229-37. Epub 2007 Mar 1. PubMed PMID: 17332453. 759: Heeringa J, van der Kuip DA, Hofman A, Kors JA, van Rooij FJ, Lip GY, Witteman JC. Subclinical atherosclerosis and risk of atrial fibrillation: the rotterdam study. Arch Intern Med. 2007 Feb 26;167(4):382-7. PubMed PMID: 17325300. 760: Karthikeyan VJ, Lip GY. Statins and intra-plaque angiogenesis in carotid artery disease. Atherosclerosis. 2007 Jun;192(2):455-6. Epub 2007 Feb 26. PubMed PMID: 17324435. 761: Thrall G, Lane D, Carroll D, Lip GY. A systematic review of the effects of acute psychological stress and physical activity on haemorheology, coagulation, fibrinolysis and platelet reactivity: Implications for the pathogenesis of acute coronary syndromes. Thromb Res. 2007;120(6):819-47. Epub 2007 Feb 23. Review. PubMed PMID: 17321571. 762: Shantsila E, Watson T, Lip GY. Antioxidant protection: yet another function of endothelial progenitor cells? J Hum Hypertens. 2007 May;21(5):343-6. Epub 2007 Feb 22. PubMed PMID: 17314998. 763: Jessani S, Lip GY. Is it the post-challenge hyperglycaemic spike or arterial stiffness we should be screening for? Int J Clin Pract. 2007 Mar;61(3):356-8. PubMed PMID: 17313598. 764: Shantsila E, Watson T, Lip GY. Endothelial progenitor cells in cardiovascular disorders. J Am Coll Cardiol. 2007 Feb 20;49(7):741-52. Review. PubMed PMID: 17306702. 765: Lip GY, Barnett AH, Bradbury A, Cappuccio FP, Gill PS, Hughes E, Imray C, Jolly K, Patel K. Ethnicity and cardiovascular disease prevention in the United Kingdom: a practical approach to management. J Hum Hypertens. 2007 Mar;21(3):183-211. Review. PubMed PMID: 17301805. 104 766: Lip GY, Frison L, Grind M; SPORTIF Invetigators. Effect of hypertension on anticoagulated patients with atrial fibrillation. Eur Heart J. 2007 Mar;28(6):752-9. Epub 2007 Feb 8. PubMed PMID: 17289744. 767: Nadar SK, Lip GY. New insights into complement C3 and inflammation in hypertension. J Hum Hypertens. 2007 Apr;21(4):261-3. Epub 2007 Feb 8. PubMed PMID: 17287839. 768: Chung I, Choudhury A, Lip GY. Platelet activation in acute, decompensated congestive heart failure. Thromb Res. 2007;120(5):709-13. Epub 2007 Feb 6. PubMed PMID: 17287016. 769: Jessani S, Lip GY, Barnett A, Millane T. The JBS-2 guidelines on prevention of cardiovascular disease in clinical practice: an opportunity missed. QJM. 2007 Feb;100(2):121-4. PubMed PMID: 17277318. 770: Lane DA, Jajoo J, Taylor RS, Lip GY, Jolly K; Birmingham Rehabilitation Uptake Maximisation (BRUM) Steering Committee. Cross-cultural adaptation into Punjabi of the English version of the Hospital Anxiety and Depression Scale. BMC Psychiatry. 2007 Jan 26;7:5. PubMed PMID: 17257405; PubMed Central PMCID: PMC1794410. 771: Choudhury A, Chung I, Blann A, Lip GY. Platelet adhesion in atrial fibrillation. Thromb Res. 2007;120(4):623-9. Epub 2007 Jan 23. PubMed PMID: 17250878. 772: Caine GJ, Ryan P, Lip GY, Blann AD. Significant decrease in angiopoietin-1 and angiopoietin-2 after radical prostatectomy in prostate cancer patients. Cancer Lett. 2007 Jun 28;251(2):296-301. Epub 2007 Jan 19. PubMed PMID: 17240049. 773: Lip GY, Rudolf M, Kakar P. Management of atrial fibrillation: the NICE guidelines. Int J Clin Pract. 2007 Jan;61(1):9-11. PubMed PMID: 17229173. 774: Watson T, Kakar P, Lip GY. Stroke risk stratification in atrial fibrillation: something to EXAMINE more closely. Int J Clin Pract. 2007 Jan;61(1):6-9. Erratum in: Int J Clin Pract. 2007 Mar;61(3):534. PubMed PMID: 17229172. 105 775: Spencer CG, Felmeden DC, Blann AD, Lip GY. Haemorheological, platelet and endothelial indices in relation to global measures of cardiovascular risk in hypertensive patients: a substudy of the Anglo-Scandinavian Cardiac Outcomes Trial. J Intern Med. 2007 Jan;261(1):82-90. PubMed PMID: 17222171. 776: Jaumdally RJ, Varma C, MacFadyen RJ, Lip GY. Effects of low osmolar contrast (iomeprol) on haemorheology and platelet activation in patients with coronary artery disease. J Thromb Thrombolysis. 2007 Jun;23(3):189-94. Epub 2007 Jan 13. PubMed PMID: 17221325. 777: Karthikeyan VJ, Lip GY. Review: Angiotensin converting enzyme inhibitors and angiotensin receptor blockers prevent atrial fibrillation. Evid Based Med. 2006 Feb;11(1):15. PubMed PMID: 17213057. 778: Patel JV, Sosin M, Lim HS, Chung I, Panja N, Davis RC, Hughes EA, Lip GY. Raised leptin concentrations among South Asian patients with chronic heart failure. Int J Cardiol. 2007 Oct 31;122(1):34-40. Epub 2006 Dec 21. PubMed PMID: 17187880. 779: Karthikeyan VJ, Lip GY. N-terminal pro-brain natriuretic peptide and coronary artery disease. Eur J Clin Invest. 2007 Jan;37(1):1-7. PubMed PMID: 17181561. 780: Kakar P, Gunarathne A, Lip GY. Stroke: ethnic differences do exist. Expert Rev Neurother. 2006 Dec;6(12):1769-71. PubMed PMID: 17181422. 781: Watson T, Lip GY. Management of atrial fibrillation. Herz. 2006 Dec;31(9):849-56. Review. PubMed PMID: 17180647. 782: Lip GY, Karpha M. Anticoagulant and antiplatelet therapy use in patients with atrial fibrillation undergoing percutaneous coronary intervention: the need for consensus and a management guideline. Chest. 2006 Dec;130(6):1823-7. PubMed PMID: 17167003. 783: Boos CJ, Jaumdally RJ, MacFadyen RJ, Varma C, Lip GY. Circulating endothelial cells and von Willebrand factor as indices of endothelial damage/dysfunction in coronary artery disease: a comparison of central vs. 106 peripheral levels and effects of coronary angioplasty. J Thromb Haemost. 2007 Mar;5(3):630-2. Epub 2006 Nov 30. PubMed PMID: 17155959. 784: Karthikeyan VJ, Lip GY. Oxidative stress and hypertension. Int J Clin Pract. 2006 Dec;60(12):1525-7. PubMed PMID: 17109661. 785: Kakar P, Lane D, Lip GY. Bleeding risk stratification models in deciding on anticoagulation in patients with atrial fibrillation: a useful complement to stroke risk stratification schema. Chest. 2006 Nov;130(5):1296-9. PubMed PMID: 17099002. 786: Hamaad A, Kaeng Lee W, Lip GY, MacFadyen RJ. Oral omega n3-PUFA therapy (Omacor) has no impact on indices of heart rate variability in stable post myocardial infarction patients. Cardiovasc Drugs Ther. 2006 Oct;20(5):359-64. PubMed PMID: 17089085. 787: Kakar P, Lip GY. Atrial fibrillation and stroke prevention. Expert Rev Neurother. 2006 Oct;6(10):1523-30. Review. PubMed PMID: 17078791. 788: Karthikeyan VJ, Lip GY. Aortic elasticity, left ventricular geometry and diastolic dysfunction in hypertension. Int J Clin Pract. 2006 Nov;60(11):1337-40. PubMed PMID: 17073829. 789: Karthikeyan VJ, Lip GY. Antihypertensive treatment, adiponectin and cardiovascular risk. J Hum Hypertens. 2007 Jan;21(1):8-11. Epub 2006 Oct 26. Review. PubMed PMID: 17066083. 790: Watson T, Shantsila E, Lip GY. Fibrin D-dimer levels and thromboembolic events in patients with atrial fibrillation. Int J Cardiol. 2007 Aug 9;120(1):123-4; author reply 125-6. Epub 2006 Oct 19. PubMed PMID: 17055595. 791: Boos CJ, Lip GY. Assessment of mean platelet volume in coronary artery disease - what does it mean? Thromb Res. 2007;120(1):11-3. Epub 2006 Oct 12. PubMed PMID: 17046049. 792: Boos CJ, Lip GY, Blann AD. Circulating endothelial cells in cardiovascular disease. J Am Coll Cardiol. 2006 Oct 17;48(8):1538-47. Epub 2006 Sep 26. Review. 107 PubMed PMID: 17045885. 793: Jessani S, Lip GY. Death or heart failure post acute myocardial infarction? The role of cardiac biomarkers. J Card Fail. 2006 Oct;12(8):641-3. Review. PubMed PMID: 17045184. 794: Chung I, Lip GY. Platelets and heart failure. Eur Heart J. 2006 Nov;27(22):2623-31. Epub 2006 Oct 6. Review. PubMed PMID: 17028108. 795: Chong AY, Freestone B, Lim HS, Kistorp C, Gustafsson F, Hildebrandt P, Lip GY. Plasma von Willebrand factor and soluble E-selectin levels in stable outpatients with systolic heart failure: the Frederiksberg heart failure study. Int J Cardiol. 2007 Jun 25;119(1):80-2. Epub 2006 Oct 5. PubMed PMID: 17027106. 796: Boos CJ, Lip GY. Platelet activation and cardiovascular outcomes in acute coronary syndromes. J Thromb Haemost. 2006 Dec;4(12):2542-3. Epub 2006 Oct 5. PubMed PMID: 17026647. 797: Karpha M, Lip GV. The pathophysiology of target organ damage in hypertension. Minerva Cardioangiol. 2006 Aug;54(4):417-29. Review. PubMed PMID: 17016413. 798: Shantsila E, Watson T, Lip GY. Aspirin resistance: what, why and when? Thromb Res. 2007;119(5):551-4. Epub 2006 Sep 27. Review. PubMed PMID: 17010411. 799: Goon PK, Lip GY. Proteomics, metabolomics and circulating endothelial progenitor cells in acute coronary syndromes. J Thromb Thrombolysis. 2006 Oct;22(2):155-6. PubMed PMID: 17008983. 800: Boos CJ, Lane DA, Kang D, Goon PK, Blann AD, Lip GY. Temporal and venepuncture-related decline in circulating endothelial cell capture from mixed venous blood. J Thromb Thrombolysis. 2006 Oct;22(2):125-31. PubMed PMID: 17008979. 801: Varughese GI, Patel JV, Tomson J, Lip GY. Effects of blood pressure on the prothrombotic risk in 1235 patients with non-valvular atrial fibrillation. Heart. 2007 Apr;93(4):495-9. Epub 2006 Sep 27. PubMed PMID: 17005711; PubMed Central 108 PMCID: PMC1861468. 802: Shantsila E, Watson T, Lip GY. Anticoagulation for stroke prevention: high effectiveness, more cost benefit? Pharmacoeconomics. 2006;24(10):1035-8. PubMed PMID: 17002485. 803: Boos CJ, Lip GY. C-reactive protein and lone atrial fibrillation: potential confounders. Am J Cardiol. 2006 Oct 1;98(7):991-2. Epub 2006 Jul 26. PubMed PMID: 16996892. 804: Patel JV, Cummings DE, Girod JP, Mascarenhas AV, Hughes EA, Gupta M, Lip GY, Reddy S, Brotman DJ. Role of metabolically active hormones in the insulin resistance associated with short-term glucocorticoid treatment. J Negat Results Biomed. 2006 Sep 11;5:14. PubMed PMID: 16965635; PubMed Central PMCID: PMC1578582. 805: Sulke N, Sayers F, Lip GY; Guideline Development Group for the NICE clinical guideline for the management of atrial fibrillation. Rhythm control and cardioversion. Heart. 2007 Jan;93(1):29-34. Epub 2006 Sep 8. Review. PubMed PMID: 16963490; PubMed Central PMCID: PMC1861343. 806: Tello-Montoliu A, Patel JV, Lip GY. Angiogenin: a review of the pathophysiology and potential clinical applications. J Thromb Haemost. 2006 Sep;4(9):1864-74. Review. PubMed PMID: 16961595. 807: Dewar RI, Lip GY; Guidelines Development Group for the NICE clinical guideline for the management of atrial fibrillation. Identification, diagnosis and assessment of atrial fibrillation. Heart. 2007 Jan;93(1):25-8. Epub 2006 Sep 4. Review. PubMed PMID: 16952973; PubMed Central PMCID: PMC1861326. 808: Camm AJ, Savelieva I, Lip GY; Guideline Development Group for the NICE clinical guideline for the management of atrial fibrillation. Rate control in the medical management of atrial fibrillation. Heart. 2007 Jan;93(1):35-8. Epub 2006 Sep 4. Review. PubMed PMID: 16952972; PubMed Central PMCID: PMC1861356. 809: Kalra L, Lip GY; Guideline Development Group for the NICE clinical guideline for the management of atrial fibrillation. Antithrombotic treatment in atrial fibrillation. Heart. 2007 Jan;93(1):39-44. Epub 2006 Sep 4. Review. PubMed PMID: 109 16952971; PubMed Central PMCID: PMC1861321. 810: Mann CJ, Kendall S, Lip GY; Guideline Development Group for the NICE clinical guideline for the management of atrial fibrillation. Acute management of atrial fibrillation with acute haemodynamic instability and in the postoperative setting. Heart. 2007 Jan;93(1):45-7. Epub 2006 Sep 4. Review. PubMed PMID: 16952970; PubMed Central PMCID: PMC1861334. 811: Davis M, Rodgers S, Rudolf M, Hughes M, Lip GY; Guideline Development Group for the NICE clinical guideline for the management of atrial fibrillation. Patient care pathway, implementation and audit criteria for patients with atrial fibrillation. Heart. 2007 Jan;93(1):48-52. Epub 2006 Sep 4. Review. PubMed PMID: 16952969; PubMed Central PMCID: PMC1861348. 812: Lip GY, Rudolf M. The new NICE guideline on atrial fibrillation management. Heart. 2007 Jan;93(1):23. Epub 2006 Sep 4. PubMed PMID: 16952968; PubMed Central PMCID: PMC1861318. 813: Nadar S, Blann AD, Lip GY. Effects of aspirin on intra-platelet vascular endothelial growth factor, angiopoietin-1, and p-selectin levels in hypertensive patients. Am J Hypertens. 2006 Sep;19(9):970-7; discussion 978. PubMed PMID: 16942942. 814: Kakar P, Lip GY. Towards understanding the aetiology and pathophysiology of human hypertension: where are we now? J Hum Hypertens. 2006 Nov;20(11):833-6. Epub 2006 Aug 24. PubMed PMID: 16929340. 815: Kakar P, Lip GY. Towards improving the clinical assessment and management of human hypertension: An overview from this Journal. J Hum Hypertens. 2006 Dec;20(12):913-6. Epub 2006 Aug 24. Review. PubMed PMID: 16929339. 816: Karthikeyan VJ, Lip GY. Vasculoprotective effects of angiotensin receptor blockers: beyond the renin-angiotensin-aldosterone system? J Hypertens. 2006 Sep;24(9):1715-7. PubMed PMID: 16915019. 817: Boos CJ, Mayr FB, Lip GY, Jilma B. Endotoxemia enhances circulating endothelial cells in humans. J Thromb Haemost. 2006 Nov;4(11):2509-11. Epub 2006 Aug 14. PubMed PMID: 16907929. 110 818: Goon PK, Lip GY. Arterial disease and venous thromboembolism: a modern paradigm? Thromb Haemost. 2006 Aug;96(2):111-2. PubMed PMID: 16894450. 819: Caine GJ, Stonelake PS, Lip GY, Blann AD. Changes in plasma vascular endothelial growth factor, angiopoietins, and their receptors following surgery for breast cancer. Cancer Lett. 2007 Apr 8;248(1):131-6. Epub 2006 Aug 7. PubMed PMID: 16891056. 820: Lip GY, Lane D, Van Walraven C, Hart RG. Additive role of plasma von Willebrand factor levels to clinical factors for risk stratification of patients with atrial fibrillation. Stroke. 2006 Sep;37(9):2294-300. Epub 2006 Aug 3. Erratum in: Stroke. 2006 Sep;37(9):2444. PubMed PMID: 16888271. 821: Hurley V, Ireson R, Fletcher K, Lip GY, Hobbs FD, Mant J; BAFTA Investigators. A cross-sectional study of hypertension in an elderly population (75 years and over) with atrial fibrillation: secondary analysis of data from the Birmingham Atrial Fibrillation in the Aged (BAFTA) randomised controlled trial. Int J Cardiol. 2007 Apr 25;117(2):152-6. Epub 2006 Aug 2. PubMed PMID: 16887213. 822: Goon PK, Messerli FH, Lip GY. Hypertension and breast cancer: an association revisited? J Hum Hypertens. 2006 Oct;20(10):722-4. Epub 2006 Aug 3. PubMed PMID: 16885997. 823: Patel JV, Lim HS, Hughes EA, Lip GY. Adiponectin and hypertension: a putative link between adipocyte function and atherosclerotic risk? J Hum Hypertens. 2007 Jan;21(1):1-4. Epub 2006 Jul 27. Review. PubMed PMID: 16871286. 824: Shantsila E, Watson T, Lip GY. Atrial fibrillation post-cardiac surgery: changing perspectives. Curr Med Res Opin. 2006 Aug;22(8):1437-41. Review. PubMed PMID: 16870069. 825: Lip GY. Antithrombotic therapy: standard therapy in essential hypertension? Prog Cardiovasc Dis. 2006 Jul-Aug;49(1):11-5. Review. PubMed PMID: 16867846. 826: Chong AY, Lip GY. Viewpoint: the prothrombotic state in heart failure: a maladaptive inflammatory response? Eur J Heart Fail. 2007 Feb;9(2):124-8. Epub 111 2006 Jul 21. Review. PubMed PMID: 16859990. 827: Lip GY, Tello-Montoliu A. Management of atrial fibrillation. Heart. 2006 Aug;92(8):1177-82. Review. PubMed PMID: 16844883; PubMed Central PMCID: PMC1861122. 828: Heeringa J, Conway DS, van der Kuip DA, Hofman A, Breteler MM, Lip GY, Witteman JC. A longitudinal population-based study of prothrombotic factors in elderly subjects with atrial fibrillation: the Rotterdam Study 1990-1999. J Thromb Haemost. 2006 Sep;4(9):1944-9. Epub 2006 Jul 5. PubMed PMID: 16824187. 829: Lip GY, Watson T, Shantsila E. Anticoagulation for stroke prevention in atrial fibrillation: is gender important? Eur Heart J. 2006 Aug;27(16):1893-4. Epub 2006 Jul 4. PubMed PMID: 16820368. 830: Goon PK, Boos CJ, Stonelake PS, Blann AD, Lip GY. Detection and quantification of mature circulating endothelial cells using flow cytometry and immunomagnetic beads: a methodological comparison. Thromb Haemost. 2006 Jul;96(1):45-52. PubMed PMID: 16807650. 831: Lee KW, Blann AD, Jolly K, Lip GY; BRUM Investigators. Plasma haemostatic markers, endothelial function and ambulatory blood pressure changes with home versus hospital cardiac rehabilitation: the Birmingham Rehabilitation Uptake Maximisation Study. Heart. 2006 Dec;92(12):1732-8. Epub 2006 Jun 28. PubMed PMID: 16807272; PubMed Central PMCID: PMC1861270. 832: Lip GY, Blann AD. 'Association of platelet function in hypertensive patients with left ventricular hypertrophy'. Platelets. 1999;10(1):71-2. PubMed PMID: 16801075. 833: Patel JV, Lee KW, Tomson J, Dubb K, Hughes EA, Lip GY. Effects of omega-3 polyunsaturated fatty acids on metabolically active hormones in patients post-myocardial infarction. Int J Cardiol. 2007 Jan 31;115(1):42-5. Epub 2006 Jun 15. PubMed PMID: 16781788. 834: Jessani S, Watson T, Cappuccio FP, Lip GY. Prevention of cardiovascular disease in clinical practice: The Joint British Societies' (JBS 2) guidelines. J Hum Hypertens. 2006 Sep;20(9):641-5. Epub 2006 Jun 1. PubMed PMID: 16738683. 112 835: Watson T, Shantsila E, Lip GY. Pharmacotherapy for atrial fibrillation: is rhythm control achievable? Expert Opin Pharmacother. 2006 Jun;7(9):1105-7. PubMed PMID: 16732697. 836: Nieuwlaat R, Capucci A, Lip GY, Olsson SB, Prins MH, Nieman FH, López-Sendón J, Vardas PE, Aliot E, Santini M, Crijns HJ; Euro Heart Survey Investigators. Antithrombotic treatment in real-life atrial fibrillation patients: a report from the Euro Heart Survey on Atrial Fibrillation. Eur Heart J. 2006 Dec;27(24):3018-26. Epub 2006 May 26. PubMed PMID: 16731536. 837: Boos CJ, Lip GY. Is hypertension an inflammatory process? Curr Pharm Des. 2006;12(13):1623-35. Review. PubMed PMID: 16729874. 838: Jaumdally JR, Lip GY, Varma C. Traditional risk factors for coronary atherosclerosis in Indo Asians: the need for a reappraisal. Curr Pharm Des. 2006;12(13):1611-21. Review. PubMed PMID: 16729873. 839: Varughese GI, Patel JV, Lip GY, Varma C. Novel concepts of statin therapy for cardiovascular risk reduction in hypertension. Curr Pharm Des. 2006;12(13):1593-609. Review. PubMed PMID: 16729872. 840: Nadar SK, Tayebjee MH, Messerli F, Lip GY. Target organ damage in hypertension: pathophysiology and implications for drug therapy. Curr Pharm Des. 2006;12(13):1581-92. Review. PubMed PMID: 16729871. 841: Lim HS, MacFadyen RJ, Bakris G, Lip GY. The role of hyperglycaemia and the hypercoagulable state in the pathogenesis of cardiovascular events in diabetes mellitus: implications for hypertension management. Curr Pharm Des. 2006;12(13):1567-79. Review. PubMed PMID: 16729870. 842: Lip GY. Aspirin for prevention of stroke in atrial fibrillation. Stroke. 2006 Jul;37(7):1640. Epub 2006 May 25. PubMed PMID: 16728675. 843: Lane DA, Boos CJ, Lip GY. Anticoagulation control with vitamin K antagonists: how well are we doing? Chest. 2006 May;129(5):1122-4. PubMed PMID: 16684999. 113 844: Thrall G, Lane D, Carroll D, Lip GY. Quality of life in patients with atrial fibrillation: a systematic review. Am J Med. 2006 May;119(5):448.e1-19. Review. PubMed PMID: 16651058. 845: Boos CJ, Lip GY. Urotensin and cardiovascular risk among patients with end-stage renal disease: fact or fiction? Am J Hypertens. 2006 May;19(5):511-2. Review. PubMed PMID: 16647625. 846: Tan KT, Lip GY. Platelet microparticles and platelet adhesion: therapeutic implications for the prevention and treatment of stroke. Curr Treat Options Cardiovasc Med. 2006 May;8(3):251-8. PubMed PMID: 16635445. 847: Boos CJ, Lip GY. Ximelagatran: an eulogy. Thromb Res. 2006;118(3):301-4. Epub 2006 Apr 19. PubMed PMID: 16626788. 848: Tello-Montoliu A, Roldán V, Climent VE, Sogorb F, Lip GY, Marín F. Does smoking status influence the effect of physical exercise on fibrinolytic function in healthy volunteers? J Thromb Thrombolysis. 2006 Apr;21(2):163-6. PubMed PMID: 16622612. 849: Lip GH, Rothwell P, Sudlow C. Stroke prevention. Clin Evid. 2005 Dec;(14):173-97. Review. PubMed PMID: 16620404. 850: Lip GY. Atrial fibrillation (recent onset). Clin Evid. 2005 Dec;(14):71-89. Review. PubMed PMID: 16620401. 851: Khan JM, Watson RD, Varma C, Millane T, Lip GY. Do the National Institute of Clinical Excellence guidelines apply to 'real world' use of Abciximab in percutaneous coronary intervention in a teaching hospital setting? Int J Clin Pract. 2006 Apr;60(4):498-9. PubMed PMID: 16620368. 852: Varughese GI, Patel JV, Lip GY. Blood pressure control in the setting of diabetes mellitus: new targets, new hope for improvement? J Hum Hypertens. 2006 Sep;20(9):635-7. Epub 2006 Apr 13. PubMed PMID: 16617307. 114 853: Watson T, Lip GY. Blood pressure measurement in atrial fibrillation: goodbye mercury? J Hum Hypertens. 2006 Sep;20(9):638-40. Epub 2006 Apr 13. PubMed PMID: 16617306. 854: Goon PK, Lip GY, Boos CJ, Stonelake PS, Blann AD. Circulating endothelial cells, endothelial progenitor cells, and endothelial microparticles in cancer. Neoplasia. 2006 Feb;8(2):79-88. Review. PubMed PMID: 16611400; PubMed Central PMCID: PMC1578513. 855: Goyal D, Tayebjee M, Lip GY, MacFadyen RJ. South Asian or Afro-Caribbean ethnicity is not associated with altered 1 min heart rate recovery estimates in suspected coronary artery disease patients. Int J Cardiol. 2007 Jan 8;114(2):261-4. Epub 2006 Mar 6. PubMed PMID: 16600405. 856: Climent VE, Picó A, Sogorb F, Aznar S, Lip GY, Marín F. Growth hormone therapy and the heart. Am J Cardiol. 2006 Apr 1;97(7):1097-102. Epub 2006 Feb 23. PubMed PMID: 16563925. 857: Goon PK, Boos CJ, Stonelake PS, Lip GY. Circulating endothelial cells in malignant disease. Future Oncol. 2005 Dec;1(6):813-20. Review. PubMed PMID: 16556061. 858: Bhatia GS, Sosin MD, Patel JV, Grindulis KA, Khattak FH, Hughes EA, Lip GY, Davis RC. Left ventricular systolic dysfunction in rheumatoid disease: an unrecognized burden? J Am Coll Cardiol. 2006 Mar 21;47(6):1169-74. Epub 2006 Feb 23. PubMed PMID: 16545648. 859: Tayebjee MH, Lip GY, Tan KT, MacFadyen RJ. Abnormal circulating neutrophil linked matrix metalloproteinase -9 in stable coronary artery disease. Thromb Haemost. 2006 Jan;95(1):202-4. PubMed PMID: 16543983. 860: Heeringa J, van der Kuip DA, Hofman A, Kors JA, van Herpen G, Stricker BH, Stijnen T, Lip GY, Witteman JC. Prevalence, incidence and lifetime risk of atrial fibrillation: the Rotterdam study. Eur Heart J. 2006 Apr;27(8):949-53. Epub 2006 Mar 9. PubMed PMID: 16527828. 861: Lip GY. Viewpoint. Circulation. 2006 Mar 7;113(9):f33-4. PubMed PMID: 16520421. 115 862: Choudhury A, Goyal D, Lip GY. Ximelagatran. Drugs Today (Barc). 2006 Jan;42(1):3-19. Review. PubMed PMID: 16511607. 863: Watson T, Lip GY. Thromboprophylaxis in atrial fibrillation: why, how, when and how can we do better? Int J Clin Pract. 2006 Mar;60(3):252-5. PubMed PMID: 16494636. 864: Chong AY, Freestone B, Patel J, Lim HS, Hughes E, Blann AD, Lip GY. Endothelial activation, dysfunction, and damage in congestive heart failure and the relation to brain natriuretic peptide and outcomes. Am J Cardiol. 2006 Mar 1;97(5):671-5. Epub 2006 Jan 10. PubMed PMID: 16490435. 865: Boos CJ, Lip GY. Prevention of atrial fibrillation by angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers. J Am Coll Cardiol. 2006 Feb 21;47(4):889-90; author reply 890-1. Epub 2006 Jan 26. PubMed PMID: 16487864. 866: Lim HS, Patel JV, Lip GY. Reactive oxygen species production by circulating monocytes: insights from pathophysiology to clinical hypertension. J Hum Hypertens. 2006 May;20(5):307-9. PubMed PMID: 16467861. 867: Karthikeyan VJ, Lip GY. Blood pressure control and prevention of stroke. Expert Rev Neurother. 2006 Feb;6(2):203-12. PubMed PMID: 16466300. 868: Boos CJ, Goon PK, Lip GY. Endothelial progenitor cells in the vascular pathophysiology of hypertension: arterial stiffness, ageing and more. J Hum Hypertens. 2006 Jul;20(7):475-7. Epub 2006 Feb 2. PubMed PMID: 16452994. 869: Karthikeyan VJ, Lip GY. Pulse pressure and carotid atherosclerosis: an important link revisited? Int J Clin Pract. 2006 Feb;60(2):127-30. PubMed PMID: 16451278. 870: Blann AD, Lip GY. Venous thromboembolism. BMJ. 2006 Jan 28;332(7535):215-9. Review. PubMed PMID: 16439400; PubMed Central PMCID: PMC1352055. 871: Karthikeyan VJ, Lip GY. White blood cell count and hypertension. J Hum 116 Hypertens. 2006 May;20(5):310-2. PubMed PMID: 16437128. 872: Karthikeyan VJ, Lip GY. Matrix metalloproteinases and hypertension: a link between left ventricular hypertrophy and diastolic dysfunction? Tohoku J Exp Med. 2006 Feb;208(2):93-7. PubMed PMID: 16434829. 873: Boos CJ, Lip GY. Assessment of hemostatic risk factors in predicting arterial thrombotic events. Arterioscler Thromb Vasc Biol. 2006 Feb;26(2):e18. PubMed PMID: 16424355. 874: Boos CJ, Goon PK, Lip GY. The endothelium, inflammation, and coagulation in sepsis. Clin Pharmacol Ther. 2006 Jan;79(1):20-2. Review. PubMed PMID: 16413238. 875: Hamaad A, Ghattas A, Hirani F, Lip GY, MacFadyen RJ. Sudden death is less common than might be expected in underprivileged ethnic minorities at high cardiovascular risk. Int J Cardiol. 2006 Feb 15;107(2):235-40. PubMed PMID: 16412803. 876: Chung I, Lip GY. Antithrombotic therapy for congestive heart failure. Int J Clin Pract. 2006 Jan;60(1):36-47. Review. PubMed PMID: 16409427. 877: Hamaad A, Sosin M, Blann AD, Patel J, Lip GY, MacFadyen RJ. Markers of inflammation in acute coronary syndromes: association with increased heart rate and reductions in heart rate variability. Clin Cardiol. 2005 Dec;28(12):570-6. PubMed PMID: 16405201. 878: Tan KT, Tayebjee MH, Lim HS, Lip GY. Clinically apparent atherosclerotic disease in diabetes is associated with an increase in platelet microparticle levels. Diabet Med. 2005 Dec;22(12):1657-62. PubMed PMID: 16401308. 879: Tayebjee MH, Lip GY, MacFadyen RJ. What role do extracellular matrix changes contribute to the cardiovascular disease burden of diabetes mellitus? Diabet Med. 2005 Dec;22(12):1628-35. Review. PubMed PMID: 16401304. 880: Freestone B, Lip GY. Managing acute and recent-onset atrial fibrillation. Evid Based Cardiovasc Med. 2003 Sep;7(3):111-6. PubMed PMID: 16379878. 117 881: Marín F, Pascual DA, Roldán V, Arribas JM, Ahumada M, Tornel PL, Oliver C, Gómez-Plana J, Lip GY, Valdés M. Statins and postoperative risk of atrial fibrillation following coronary artery bypass grafting. Am J Cardiol. 2006 Jan 1;97(1):55-60. Epub 2005 Nov 7. PubMed PMID: 16377284. 882: Tan KT, Lip GY. The assessment of platelet activation in antiplatelet drug development. Curr Med Chem. 2005;12(26):3117-25. Review. PubMed PMID: 16375705. 883: Lee KW, Blann AD, Lip GY. Plasma markers of endothelial damage/dysfunction, inflammation and thrombogenesis in relation to TIMI risk stratification in acute coronary syndromes. Thromb Haemost. 2005 Nov;94(5):1077-83. PubMed PMID: 16363252. 884: Nadar SK, Karalis I, Al Yemeni E, Blann AD, Lip GY. Plasma markers of angiogenesis in pregnancy induced hypertension. Thromb Haemost. 2005 Nov;94(5):1071-6. PubMed PMID: 16363251. 885: Boos CJ, Goon PK, Lip GY. Circulating endothelial progenitor cells. N Engl J Med. 2005 Dec 15;353(24):2613-6; author reply 2613-6. PubMed PMID: 16363024. 886: Varughese GI, Patel JV, Tomson J, Lip GY. The prothrombotic risk of diabetes mellitus in atrial fibrillation and heart failure. J Thromb Haemost. 2005 Dec;3(12):2811-3. PubMed PMID: 16359522. 887: Marinskis G, Lip GY, Aidietis A, Jurkuvenas P, Kaireviciūte D, Jezov V, Bagdonas K, Serpytis P, Laucevicius A. Blood oxygen saturation during atrio-ventricular dissociation with wide-QRS complex tachycardias. Int J Cardiol. 2006 Feb 8;107(1):134-5. Erratum in: Int J Cardiol. 2008 Jan 11;123(2):217. Adietis, Audrius [corrected to Aidietis, Audrius]. PubMed PMID: 16337516. 888: Patel JV, Lim HS, Nadar S, Tayebjee M, Hughes EA, Lip GY. Abnormal soluble CD40 ligand and C-reactive protein concentrations in hypertension: relationship to indices of angiogenesis. J Hypertens. 2006 Jan;24(1):117-21. PubMed PMID: 16331109. 889: Lee KW, Blann AD, Lip GY. Inter-relationships of indices of endothelial damage/dysfunction [circulating endothelial cells, von Willebrand factor and 118 flow-mediated dilatation] to tissue factor and interleukin-6 in acute coronary syndromes. Int J Cardiol. 2006 Aug 10;111(2):302-8. Epub 2005 Dec 1. PubMed PMID: 16324758. 890: Freestone B, Chong AY, Blann AD, Lip GY. The effects of direct current cardioversion for persistent atrial fibrillation on indices of endothelial damage/dysfunction. Thromb Res. 2006;118(4):479-85. Epub 2005 Nov 28. PubMed PMID: 16318868. 891: Jolly K, Taylor RS, Lip GY, Stevens A. Home-based cardiac rehabilitation compared with centre-based rehabilitation and usual care: a systematic review and meta-analysis. Int J Cardiol. 2006 Aug 28;111(3):343-51. Epub 2005 Nov 28. Review. PubMed PMID: 16316695. 892: Roldán V, Marín F, García A, Tello-Montoliu A, Lip GY. Is an advanced age an additive risk factor to the prothrombotic or hypercoagulable state in atrial fibrillation? Int J Cardiol. 2006 Jun 16;110(2):265-6. Epub 2005 Nov 28. PubMed PMID: 16316692. 893: Lim HS, Tayebjee MH, Tan KT, Patel JV, Macfadyen RJ, Lip GY. Serum adiponectin in coronary heart disease: ethnic differences and relation to coronary artery disease severity. Heart. 2005 Dec;91(12):1605-6. PubMed PMID: 16287748; PubMed Central PMCID: PMC1769205. 894: Goon PK, Boos CJ, Lip GY. Circulating endothelial cells: markers of vascular dysfunction. Clin Lab. 2005;51(9-10):531-8. Review. PubMed PMID: 16285476. 895: Boos CJ, Anderson RA, Lip GY. Is atrial fibrillation an inflammatory disorder? Eur Heart J. 2006 Jan;27(2):136-49. Epub 2005 Nov 8. Review. PubMed PMID: 16278230. 896: Lip GY, Varughese GI. Diabetes mellitus and atrial fibrillation: perspectives on epidemiological and pathophysiological links. Int J Cardiol. 2005 Dec 7;105(3):319-21. PubMed PMID: 16274776. 897: Lip GY, Varma C. Anticoagulation plus aspirin following acute myocardial infarction: yes or no ... and if the latter, why not? Thromb Res. 2006;118(4):429-32. Epub 2005 Nov 7. Review. PubMed PMID: 16274734. 119 898: Nadar SK, Lip GY, Lee KW, Blann AD. Circulating endothelial cells in acute ischaemic stroke. Thromb Haemost. 2005 Oct;94(4):707-12. PubMed PMID: 16270621. 899: Freestone B, Lip GY, Chong AY, Nadar S, Lee KW, Blann AD. Circulating endothelial cells in atrial fibrillation with and without acute cardiovascular disease. Thromb Haemost. 2005 Oct;94(4):702-6. PubMed PMID: 16270620. 900: Tan KT, Lip GY. The potential role of platelet microparticles in atherosclerosis. Thromb Haemost. 2005 Sep;94(3):488-92. Review. PubMed PMID: 16268460. 901: Boos CJ, Lip GY. Biomarkers in atrial fibrillation: further observations on biologic plausibility, cause and effect. J Thromb Thrombolysis. 2005 Dec;20(3):189-90. PubMed PMID: 16261294. 902: Lip GY, Boos CJ. Ethnic differences in arterial responses, inflammation, and metabolic profiles: possible insights into ethnic differences in cardiovascular disease and stroke. Arterioscler Thromb Vasc Biol. 2005 Nov;25(11):2240-2. PubMed PMID: 16258149. 903: Felmeden DC, Lip GY. Endothelial function and its assessment. Expert Opin Investig Drugs. 2005 Nov;14(11):1319-36. Review. PubMed PMID: 16255673. 904: Lane DA, Ponsford J, Shelley A, Sirpal A, Lip GY. Patient knowledge and perceptions of atrial fibrillation and anticoagulant therapy: effects of an educational intervention programme. The West Birmingham Atrial Fibrillation Project. Int J Cardiol. 2006 Jun 28;110(3):354-8. Epub 2005 Oct 25. PubMed PMID: 16253356. 905: Tomson J, Lip GY. Alcohol and hypertension: an old relationship revisited. Alcohol Alcohol. 2006 Jan-Feb;41(1):3-4. Epub 2005 Oct 20. PubMed PMID: 16239351. 906: Choudhury A, Varughese GI, Lip GY. Targeting the renin-angiotensin-aldosterone-system in atrial fibrillation: a shift from electrical to structural therapy? Expert Opin Pharmacother. 2005 Oct;6(13):2193-207. Review. PubMed PMID: 16218881. 120 907: Lee KW, Blann AD, Lip GY. Impaired tissue Doppler diastolic function in patients with coronary artery disease: relationship to endothelial damage/dysfunction and platelet activation. Am Heart J. 2005 Oct;150(4):756-66. PubMed PMID: 16209979. 908: Bhatia GS, Sosin MD, Khattak FH, Davis RC, Lip GY. Rheumatoid disease and ischaemic heart disease: insights from pathophysiology and vascular biology. Int J Cardiol. 2005 Oct 20;105(1):1-10. Review. PubMed PMID: 16207538. 909: Hobbs FD, Fitzmaurice DA, Mant J, Murray E, Jowett S, Bryan S, Raftery J, Davies M, Lip G. A randomised controlled trial and cost-effectiveness study of systematic screening (targeted and total population screening) versus routine practice for the detection of atrial fibrillation in people aged 65 and over. The SAFE study. Health Technol Assess. 2005 Oct;9(40):iii-iv, ix-x, 1-74. PubMed PMID: 16202350. 910: Lip GY, Edwards SJ. Stroke prevention with aspirin, warfarin and ximelagatran in patients with non-valvular atrial fibrillation: a systematic review and meta-analysis. Thromb Res. 2006;118(3):321-33. Epub 2005 Sep 29. Review. PubMed PMID: 16198396. 911: MacFadyen RJ, Goyal D, Lip GY. How far can population epidemiology contribute to defining the relationship between hypertension and left ventricular systolic dysfunction? J Hum Hypertens. 2005 Dec;19(12):919-22. PubMed PMID: 16195708. 912: Tan KT, Tayebjee MH, Macfadyen RJ, Lip GY, Blann AD. Elevated platelet microparticles in stable coronary artery disease are unrelated to disease severity or to indices of inflammation. Platelets. 2005 Sep;16(6):368-71. PubMed PMID: 16194867. 913: Chong AY, Lip GY, Freestone B, Blann AD. Increased circulating endothelial cells in acute heart failure: comparison with von Willebrand factor and soluble E-selectin. Eur J Heart Fail. 2006 Mar;8(2):167-72. Epub 2005 Sep 26. PubMed PMID: 16185922. 914: Freestone B, Chong AY, Lim HS, Blann A, Lip GY. Angiogenic factors in atrial 121 fibrillation: a possible role in thrombogenesis? Ann Med. 2005;37(5):365-72. PubMed PMID: 16179272. 915: Lane DA, Lip GY. Anticoagulation as thromboprophylaxis for atrial fibrillation: implications in the 'real world' and the need for risk stratification. Blood Coagul Fibrinolysis. 2005 Oct;16(7):461-4. PubMed PMID: 16175003. 916: Nadar SK, Blann A, Beevers DG, Lip GY. Abnormal angiopoietins 1&2, angiopoietin receptor Tie-2 and vascular endothelial growth factor levels in hypertension: relationship to target organ damage [a sub-study of the Anglo-Scandinavian Cardiac Outcomes Trial (ASCOT)]. J Intern Med. 2005 Oct;258(4):336-43. PubMed PMID: 16164572. 917: Lip GY, Boos CJ. Antithrombotic treatment in atrial fibrillation. Heart. 2006 Feb;92(2):155-61. Epub 2005 Sep 13. Review. PubMed PMID: 16159980; PubMed Central PMCID: PMC1860779. 918: Lee KW, Blann AD, Lip GY. Effects of omega-3 polyunsaturated fatty acids on plasma indices of thrombogenesis and inflammation in patients post-myocardial infarction. Thromb Res. 2006;118(3):305-12. Epub 2005 Sep 8. PubMed PMID: 16154181. 919: Boos CJ, Lip GY. Blood clotting, inflammation, and thrombosis in cardiovascular events: perspectives. Front Biosci. 2006 Jan 1;11:328-36. Review. PubMed PMID: 16146734. 920: Hamaad A, Sosin M, Lip GY, MacFadyen RJ. Short-term adjuvant atorvastatin improves frequency domain indices of heart rate variability in stable systolic heart failure. Cardiovasc Drugs Ther. 2005 May;19(3):183-7. PubMed PMID: 16142595. 921: Varma C, Lip GY. Failed reperfusion with thrombolysis--the effect of a local environment? Thromb Res. 2006;118(2):185-7. Epub 2005 Aug 31. PubMed PMID: 16139334. 922: Schulman S, Lip GY. Ximelagatran in the clinic: practical management of patients. Semin Vasc Med. 2005 Aug;5(3):301-7. Review. PubMed PMID: 16123918. 122 923: Karalis I, Nadar SK, Al Yemeni E, Blann AD, Lip GY. Platelet activation in pregnancy-induced hypertension. Thromb Res. 2005;116(5):377-83. Epub 2005 Feb 24. PubMed PMID: 16122550. 924: Jaumdally R, Lip GY, Varma C. Percutaneous coronary interventions for coronary artery disease: the long and short of optimizing medical therapy. Int J Clin Pract. 2005 Sep;59(9):1070-81. Review. PubMed PMID: 16115184. 925: Lim HS, Lip GY. Interleukin-15 in hypertension: further insights into inflammation and vascular disease. Am J Hypertens. 2005 Aug;18(8):1017-8. PubMed PMID: 16109313. 926: Boos CJ, Lip GY. Targeting the renin-angiotensin-aldosterone system in atrial fibrillation: from pathophysiology to clinical trials. J Hum Hypertens. 2005 Nov;19(11):855-9. PubMed PMID: 16094406. 927: Thrall G, Lane D, Lip GY. Differences in the platelet reactivity response to mental stress in cardiac syndrome X patients compared to known coronary artery disease patients: concepts, explanations and methodological weaknesses. Thromb Res. 2006;117(3):351-2. Epub 2005 Aug 9. PubMed PMID: 16084573. 928: Boos CJ, Hinton A, Lip GY. Ximelagatran: a clinical perspective. Eur J Intern Med. 2005 Aug;16(4):267-78. PubMed PMID: 16084353. 929: Varughese GI, Lip GY. Antihypertensive therapy in diabetes mellitus: insights from ALLHAT and the Blood Pressure-Lowering Treatment Trialists' Collaboration meta-analysis. J Hum Hypertens. 2005 Nov;19(11):851-3. PubMed PMID: 16079882. 930: Tomson J, Lip GY. Blood pressure changes in acute haemorrhagic stroke. Blood Press Monit. 2005 Aug;10(4):197-9. Review. PubMed PMID: 16077265. 931: Boos CJ, Lip GY. Ximelagatran for stroke prevention in atrial fibrillation. Expert Rev Cardiovasc Ther. 2005 Jul;3(4):551-63. Review. PubMed PMID: 16076267. 123 932: Tayebjee MH, Lip GY, Tan KT, Patel JV, Hughes EA, MacFadyen RJ. Plasma matrix metalloproteinase-9, tissue inhibitor of metalloproteinase-2, and CD40 ligand levels in patients with stable coronary artery disease. Am J Cardiol. 2005 Aug 1;96(3):339-45. PubMed PMID: 16054454. 933: Mohan JS, Lip GY, Bareford D, Blann AD. Platelet P-selectin and platelet mass, volume and component in sickle cell disease: relationship to genotype. Thromb Res. 2006;117(6):623-9. Epub 2005 Jul 27. PubMed PMID: 16051315. 934: Roldán V, Marín F, García-Herola A, Lip GY. Correlation of plasma von Willebrand factor levels, an index of endothelial damage/dysfunction, with two point-based stroke risk stratification scores in atrial fibrillation. Thromb Res. 2005;116(4):321-5. Epub 2005 Feb 8. PubMed PMID: 16038717. 935: Lip GY, Chung I. Antiplatelet and anticoagulant therapy in patients with advanced heart failure. Thromb Res. 2005;116(4):275-7. Epub 2005 Feb 8. PubMed PMID: 16038710. 936: Bhatia GS, Lip GY. Atrial fibrillation post-myocardial infarction: frequency, consequences, and management. Curr Heart Fail Rep. 2004 Dec;1(4):149-55. Review. PubMed PMID: 16036038. 937: Boos CJ, Lip GY. The role of inflammation in atrial fibrillation. Int J Clin Pract. 2005 Aug;59(8):870-2. PubMed PMID: 16033603. 938: Tan KT, Tayebjee MH, Macfadyen RJ, Lip GY. Relation of platelet activation to coronary angiographic severity and collateralization. Am J Cardiol. 2005 Jul 15;96(2):208-10. PubMed PMID: 16018843. 939: Brotman DJ, Girod JP, Posch A, Jani JT, Patel JV, Gupta M, Lip GY, Reddy S, Kickler TS. Effects of short-term glucocorticoids on hemostatic factors in healthy volunteers. Thromb Res. 2006;118(2):247-52. Epub 2005 Jul 11. PubMed PMID: 16005496. 940: Tayebjee MH, Lip GY, Macfadyen RJ. Is there an association between hypertension and the development of coronary collateral flow? J Hum Hypertens. 2005 Oct;19(10):757-9. Review. PubMed PMID: 15988537. 124 941: Tomson J, Lip GY. Peripheral arterial disease: a high risk - but neglected disease population. BMC Cardiovasc Disord. 2005 Jun 22;5(1):15. PubMed PMID: 15972103; PubMed Central PMCID: PMC1166544. 942: Mohan JS, Lip PL, Blann AD, Bareford D, Lip GY. The angiopoietin/Tie-2 system in proliferative sickle retinopathy: relation to vascular endothelial growth factor, its soluble receptor Flt-1 and von Willebrand factor, and to the effects of laser treatment. Br J Ophthalmol. 2005 Jul;89(7):815-9. PubMed PMID: 15965157; PubMed Central PMCID: PMC1772718. 943: Varughese GI, Tomson J, Lip GY. Type 2 diabetes mellitus: a cardiovascular perspective. Int J Clin Pract. 2005 Jul;59(7):798-816. Review. PubMed PMID: 15963208. 944: Bacon SL, Ring C, Hee FL, Lip GY, Blann AD, Lavoie KL, Carroll D. Hemodynamic, hemostatic, and endothelial reactions to psychological and physical stress in coronary artery disease patients. Biol Psychol. 2006 Feb;71(2):162-70. Epub 2005 Jun 14. PubMed PMID: 15961212. 945: Lip GY. Darusentan (Abbott Laboratories). IDrugs. 2001 Nov;4(11):1284-92. PubMed PMID: 15942834. 946: Lane DA, Lip GY, Beevers DG. Ethnic differences in cardiovascular and all-cause mortality in Birmingham, England: the Birmingham Factory Screening Project. J Hypertens. 2005 Jul;23(7):1347-53. PubMed PMID: 15942456. 947: Lip GY, Freestone B. Cardioversion and the endothelium in atrial fibrillation. Thromb Res. 2006;117(3):231-3. Epub 2005 May 31. PubMed PMID: 15927240. 948: Varughese GI, Lip GY. Is hypertension a prothrombotic state? Curr Hypertens Rep. 2005 Jun;7(3):168-73. Review. PubMed PMID: 15913489. 949: Chong AY, Chin BS, Blann AD, Lip GY. Effects of antiplatelet therapy and oral anticoagulation on indices of endothelial damage/dysfunction in patients with systolic heart failure in sinus rhythm. Thromb Res. 2005;116(2):181-3. Epub 2005 Jan 18. PubMed PMID: 15907534. 125 950: Choudhury A, Lip GY. Exercise and hypertension. J Hum Hypertens. 2005 Aug;19(8):585-7. PubMed PMID: 15905895. 951: Boos CJ, Lip GY. Elevated high-sensitive C-reactive protein, large arterial stiffness and atherosclerosis: a relationship between inflammation and hypertension? J Hum Hypertens. 2005 Jul;19(7):511-3. Review. PubMed PMID: 15905894. 952: Felmeden D, Nadar SK, Lip GY. Aspirin and endothelial function in hypertension. J Hum Hypertens. 2005 Sep;19(9):663-5. Review. PubMed PMID: 15905886. 953: Jolly K, Lip GY, Taylor RS, Mant JW, Lane DA, Lee KW, Stevens AJ; BRUM Steering Committee. Recruitment of ethnic minority patients to a cardiac rehabilitation trial: the Birmingham Rehabilitation Uptake Maximisation (BRUM) study [ISRCTN72884263]. BMC Med Res Methodol. 2005 May 17;5:18. PubMed PMID: 15904499; PubMed Central PMCID: PMC1166559. 954: Tan KT, Tayebjee MH, Lynd C, Blann AD, Lip GY. Platelet microparticles and soluble P selectin in peripheral artery disease: relationship to extent of disease and platelet activation markers. Ann Med. 2005;37(1):61-6. PubMed PMID: 15902848. 955: Nadar SK, Caine GJ, Blann AD, Lip GY. Platelet adhesion in hypertension: application of a novel assay of platelet adhesion. Ann Med. 2005;37(1):55-60. PubMed PMID: 15902847. 956: Lip GY, Pearce LA, Chin BS, Conway DS, Hart RG. Effects of congestive heart failure on plasma von Willebrand factor and soluble P-selectin concentrations in patients with non-valvar atrial fibrillation. Heart. 2005 Jun;91(6):759-63. PubMed PMID: 15894770; PubMed Central PMCID: PMC1768962. 957: Tayebjee MH, Lip GY. Heterotopic heart transplantation. Int J Cardiol. 2005 May 25;101(2):311-2. PubMed PMID: 15882683. 958: Lip GY, Chung I. Vascular endothelial growth factor and angiogenesis in 126 heart failure. J Card Fail. 2005 May;11(4):285-7. PubMed PMID: 15880337. 959: Lip GY, Rothwell P, Sudlow C. Stroke prevention. Clin Evid. 2004 Dec;(12):253-84. Review. Update in: Clin Evid. 2005 Dec;(14):173-97. PubMed PMID: 15865638. 960: Lip GY, Choudhury A. A prophylactically implanted cardioverter defibrillator did not reduce all-cause mortality after a recent myocardial infarction. ACP J Club. 2005 May-Jun;142(3):58. PubMed PMID: 15862057. 961: Lim HS, Lip GY, Beevers DG, Blann AD. Factors predicting the development of metabolic syndrome and type II diabetes against a background of hypertension. Eur J Clin Invest. 2005 May;35(5):324-9. PubMed PMID: 15860044. 962: Tayebjee MH, Lip GY, MacFadyen RJ. Matrix metalloproteinases in coronary artery disease: clinical and therapeutic implications and pathological significance. Curr Med Chem. 2005;12(8):917-25. Review. PubMed PMID: 15853705. 963: Lip GY, Foster W, Blann AD. Plasma von Willebrand factor levels and surrogates of atherosclerosis. J Thromb Haemost. 2005 Apr;3(4):659-61. PubMed PMID: 15842350. 964: Karalis I, Beevers G, Beevers M, Lip G. Hormone replacement therapy and arterial blood pressure in postmenopausal women with hypertension. Blood Press. 2005;14(1):38-44. PubMed PMID: 15823946. 965: Tomson J, Os I, Lip GY. Hormone replacement use and cardiovascular function and structure in postmenopausal women. Blood Press. 2005;14(1):3-5. PubMed PMID: 15823940. 966: Schmidt-Lucke C, Belgore F, Reinhold D, Ansorge S, Klein HU, Schmidt-Lucke JA, Lip GY. Soluble vascular endothelial growth factor, soluble VEGF receptor Flt-1 and endothelial function in healthy smokers. Int J Cardiol. 2005 Apr 20;100(2):207-12. PubMed PMID: 15823626. 967: Lim HS, Lip GY, Blann AD. Angiopoietin-1 and angiopoietin-2 in diabetes mellitus: relationship to VEGF, glycaemic control, endothelial damage/dysfunction 127 and atherosclerosis. Atherosclerosis. 2005 May;180(1):113-8. Epub 2004 Dec 21. PubMed PMID: 15823283. 968: López F, Lee KW, Marín F, Roldán V, Sogorb F, Caturla J, Lip GY. Are there ethnic differences in the circadian variation in onset of acute myocardial infarction? A comparison of 3 ethnic groups in Birmingham, UK and Alicante, Spain. Int J Cardiol. 2005 Apr 8;100(1):151-4. PubMed PMID: 15820298. 969: Varughese GI, Lip GY. Hypertension in patients with type-II diabetes: relation to urinary albumin excretion, endothelial function and inflammation. J Hum Hypertens. 2005 Jun;19(6):421-4. Review. PubMed PMID: 15815695. 970: Lip GY. Preventing stroke in atrial fibrillation: the SPORTIF programme. Pathophysiol Haemost Thromb. 2005;34 Suppl 1:25-30. Review. PubMed PMID: 15812201. 971: Tayebjee MH, Karalis I, Nadar SK, Beevers DG, MacFadyen RJ, Lip GY. Circulating matrix metalloproteinase-9 and tissue inhibitors of metalloproteinases-1 and -2 levels in gestational hypertension. Am J Hypertens. 2005 Mar;18(3):325-9. PubMed PMID: 15797648. 972: Mohan JS, Lip GY, Wright J, Bareford D, Blann AD. Plasma levels of tissue factor and soluble E-selectin in sickle cell disease: relationship to genotype and to inflammation. Blood Coagul Fibrinolysis. 2005 Apr;16(3):209-14. PubMed PMID: 15795541. 973: Marín F, Roldán V, Tello A, Lip GY. Genetic polymorphisms and thromoembolic risk in atrial fibrillation. J Thromb Thrombolysis. 2004 Oct;18(2):151-2. PubMed PMID: 15789181. 974: Lim HS, Patel JV, Nadar S, Hughes EA, Lip GY. Comparison of brain natriuretic peptide and left ventricular diastolic function determined by tissue Doppler in patients with diabetes mellitus, patients with hypertension without diabetes, and in healthy subjects. Am J Cardiol. 2005 Apr 1;95(7):905-8. PubMed PMID: 15781031. 975: Roldán V, Marín F, Martínez JG, García-Herola A, Sogorb F, Lip GY. Relation of interleukin-6 levels and prothrombin fragment 1+2 to a point-based score for 128 stroke risk in atrial fibrillation. Am J Cardiol. 2005 Apr 1;95(7):881-2. PubMed PMID: 15781023. 976: Lee KW, Blann AD, Ingram J, Jolly K, Lip GY; BRUM Investigators. Incremental shuttle walking is associated with activation of haemostatic and haemorheological markers in patients with coronary artery disease: the Birmingham rehabilitation uptake maximization study (BRUM). Heart. 2005 Nov;91(11):1413-7. Epub 2005 Mar 17. PubMed PMID: 15774609; PubMed Central PMCID: PMC1769168. 977: Lane D, Ring C, Lip GY, Carroll D. Depression, indirect clinical markers of cardiac disease severity, and mortality following myocardial infarction. Heart. 2005 Apr;91(4):531-2. PubMed PMID: 15772222; PubMed Central PMCID: PMC1768854. 978: Choudhury A, Lip GY. How good is anticoagulation control in non-valvar atrial fibrillation? Observations on the elderly, ethnicity, patient perceptions, and understanding of AF thromboprophylaxis. Heart. 2005 Apr;91(4):425-6. PubMed PMID: 15772186; PubMed Central PMCID: PMC1768856. 979: Brotman DJ, Girod JP, Garcia MJ, Patel JV, Gupta M, Posch A, Saunders S, Lip GY, Worley S, Reddy S. Effects of short-term glucocorticoids on cardiovascular biomarkers. J Clin Endocrinol Metab. 2005 Jun;90(6):3202-8. Epub 2005 Mar 15. PubMed PMID: 15769980. 980: Chong AY, Lip GY. Hormone replacement therapy and cardiovascular risk. Treat Endocrinol. 2002;1(2):95-103. Review. PubMed PMID: 15765625. 981: Conway DS, Lip GY. Atrial fibrillation, the prothrombotic state, inflammation, and gender. Am J Cardiol. 2005 Mar 15;95(6):819. PubMed PMID: 15757625. 982: Nadar S, Prasad N, Taylor RS, Lip GY. Positive pressure ventilation in the management of acute and chronic cardiac failure: a systematic review and meta-analysis. Int J Cardiol. 2005 Mar 18;99(2):171-85. Review. PubMed PMID: 15749172. 983: Varughese GI, Lip GY. Goodbye mercury? Blood pressure measurement and its future. J R Soc Med. 2005 Mar;98(3):89-90. PubMed PMID: 15738548; PubMed Central PMCID: PMC1079406. 129 984: Blann AD, Tan KT, Tayebjee MH, Davagnanam I, Moss M, Lip GY. Soluble CD40L in peripheral artery disease. Relationship with disease severity, platelet markers and the effects of angioplasty. Thromb Haemost. 2005 Mar;93(3):578-83. PubMed PMID: 15735813. 985: Tan KT, Lip GY. Fondaparinux. Curr Pharm Des. 2005;11(4):415-9. Review. PubMed PMID: 15725062. 986: Caine GJ, Harris AL, Christodoulos K, Lip GY, Blann AD. Analysis of combination anti-angiogenesis therapy on markers of coagulation, platelet activation and angiogenesis in patients with advanced cancer. Cancer Lett. 2005 Mar 10;219(2):163-7. PubMed PMID: 15723715. 987: Bhatia G, Sosin M, Leahy JF, Connolly DL, Davis RC, Lip GY. Hibernating myocardium in heart failure. Expert Rev Cardiovasc Ther. 2005 Jan;3(1):111-22. Review. PubMed PMID: 15723580. 988: Lim HS, Chong AY, Freestone B, Blann AD, Lip GY. The effect of multi-factorial intervention on plasma von Willebrand factor, soluble E-selectin and tissue factor in diabetes mellitus: implications for atherosclerotic vascular disease. Diabet Med. 2005 Mar;22(3):249-55. PubMed PMID: 15717870. 989: Blann AD, Woywodt A, Bertolini F, Bull TM, Buyon JP, Clancy RM, Haubitz M, Hebbel RP, Lip GY, Mancuso P, Sampol J, Solovey A, Dignat-George F. Circulating endothelial cells. Biomarker of vascular disease. Thromb Haemost. 2005 Feb;93(2):228-35. Review. PubMed PMID: 15711737. 990: Goyal D, Choudhury A, Lip GY. Thrombotic complications and thromboprophylaxis in breast and gynaecological malignancies. Curr Opin Obstet Gynecol. 2005 Feb;17(1):13-20. Review. PubMed PMID: 15711406. 991: Bhatia GS, Sosin MD, Grindulis KA, Davis RC, Lip GY. Rheumatoid disease and the heart: from epidemiology to echocardiography. Expert Opin Investig Drugs. 2005 Jan;14(1):65-76. Review. PubMed PMID: 15709923. 992: Goyal D, Macfadyen RJ, Watson RD, Lip GY. Ambulatory blood pressure 130 monitoring in heart failure: a systematic review. Eur J Heart Fail. 2005 Mar 2;7(2):149-56. Review. PubMed PMID: 15701460. 993: Dignat-George F, Sampol J, Lip G, Blann AD. Circulating endothelial cells: realities and promises in vascular disorders. Pathophysiol Haemost Thromb. 2003 Sep-2004 Dec;33(5-6):495-9. Review. PubMed PMID: 15692266. 994: Chung I, Lip GY. Virchow's triad revisited: blood constituents. Pathophysiol Haemost Thromb. 2003 Sep-2004 Dec;33(5-6):449-54. Review. PubMed PMID: 15692259. 995: Choudhury A, Lip GY. Atrial fibrillation and the hypercoagulable state: from basic science to clinical practice. Pathophysiol Haemost Thromb. 2003 Sep-2004 Dec;33(5-6):282-9. Review. PubMed PMID: 15692230. 996: Lee KW, Blann AD, Lip GY. High pulse pressure and nondipping circadian blood pressure in patients with coronary artery disease: Relationship to thrombogenesis and endothelial damage/dysfunction. Am J Hypertens. 2005 Jan;18(1):104-15. PubMed PMID: 15691624. 997: Thrall G, Lip GY. Exercise and the prothrombotic state: a paradox of cardiovascular prevention or an enhanced prothrombotic state? Arterioscler Thromb Vasc Biol. 2005 Feb;25(2):265-6. PubMed PMID: 15681304. 998: Iqbal MB, Taneja AK, Lip GY, Flather M. Recent developments in atrial fibrillation. BMJ. 2005 Jan 29;330(7485):238-43. Review. PubMed PMID: 15677659; PubMed Central PMCID: PMC546076. 999: Lane DA, Chong AY, Lip GY. Psychological interventions for depression in heart failure. Cochrane Database Syst Rev. 2005 Jan 25;(1):CD003329. Review. PubMed PMID: 15674906. 1000: Felmeden DC, Lip GY. Antithrombotic therapy in hypertension: a Cochrane Systematic review. J Hum Hypertens. 2005 Mar;19(3):185-96. Review. PubMed PMID: 15674407. 1001: Freestone B, Lip GY. Atrial fibrillation (acute). Clin Evid. 2004 Jun;(11):76-97. Review. PubMed PMID: 15652001. 131 1002: Tomson J, Lip GY. Blood pressure demographics: nature or nurture ... ... genes or environment? BMC Med. 2005 Jan 7;3:3. PubMed PMID: 15638936; PubMed Central PMCID: PMC544878. 1003: Tayebjee MH, Lim HS, Nadar S, MacFadyen RJ, Lip GY. Tissue inhibitor of metalloproteinse-1 is a marker of diastolic dysfunction using tissue doppler in patients with type 2 diabetes and hypertension. Eur J Clin Invest. 2005 Jan;35(1):8-12. PubMed PMID: 15638813. 1004: Marín F, González-Conejero R, Lee KW, Corral J, Roldán V, López F, Sogorb F, Caturla J, Lip GY, Vicente V. A pharmacogenetic effect of factor XIII valine 34 leucine polymorphism on fibrinolytic therapy for acute myocardial infarction. J Am Coll Cardiol. 2005 Jan 4;45(1):25-9. PubMed PMID: 15629368. 1005: Tayebjee MH, Lip GY, Blann AD, Macfadyen RJ. Effects of age, gender, ethnicity, diurnal variation and exercise on circulating levels of matrix metalloproteinases (MMP)-2 and -9, and their inhibitors, tissue inhibitors of matrix metalloproteinases (TIMP)-1 and -2. Thromb Res. 2005;115(3):205-10. PubMed PMID: 15617743. 1006: Thrall G, Lip GY. Haemoconcentration and the hypercoagulable state associated with mental stress. Thromb Res. 2005;115(3):171-3. PubMed PMID: 15617738. 1007: Tayebjee MH, Tan KT, MacFadyen RJ, Lip GY. Abnormal circulating levels of metalloprotease 9 and its tissue inhibitor 1 in angiographically proven peripheral arterial disease: relationship to disease severity. J Intern Med. 2005 Jan;257(1):110-6. PubMed PMID: 15606382. 1008: Lane D, Lip GY. Anti-thrombotic therapy for atrial fibrillation and patients' preferences for treatment. Age Ageing. 2005 Jan;34(1):1-3. PubMed PMID: 15591476. 1009: Nadar SK, Lip GY, Blann AD. Platelet morphology, soluble P selectin and platelet P-selectin in acute ischaemic stroke. The West Birmingham Stroke Project. Thromb Haemost. 2004 Dec;92(6):1342-8. PubMed PMID: 15583743. 132 1010: Lim HS, Felmeden D, Lip GY. Angiotensin II-mediated vascular inflammation: the balance between vascular endothelial growth factor and angiopoietins. Hypertension. 2005 Feb;45(2):e3. PubMed PMID: 15583069. 1011: Nadar S, Blann AD, Lip GY. Antihypertensive therapy and endothelial function. Curr Pharm Des. 2004;10(29):3607-14. Review. PubMed PMID: 15579057. 1012: Nadar S, Blann AD, Lip GY. Endothelial dysfunction: methods of assessment and application to hypertension. Curr Pharm Des. 2004;10(29):3591-605. Review. PubMed PMID: 15579056. 1013: Sosin MD, Bhatia GS, Lip GY, Davis RC. Drug development and the importance of ethnicity: lessons from heart failure management and implications for hypertension. Curr Pharm Des. 2004;10(29):3569-77. Review. PubMed PMID: 15579054. 1014: Boos CJ, Lip GY. Novel therapies for the prevention of stroke. Expert Opin Investig Drugs. 2004 Dec;13(12):1615-30. Review. PubMed PMID: 15566318. 1015: Lim HS, Blann AD, Chong AY, Freestone B, Lip GY. Plasma vascular endothelial growth factor, angiopoietin-1, and angiopoietin-2 in diabetes: implications for cardiovascular risk and effects of multifactorial intervention. Diabetes Care. 2004 Dec;27(12):2918-24. PubMed PMID: 15562207. 1016: Sosin MD, Bhatia GS, Davis RC, Lip GY. Heart failure--the importance of ethnicity. Eur J Heart Fail. 2004 Dec;6(7):831-43. Review. PubMed PMID: 15556044. 1017: Freestone B, Lip GY, Rothwell P, Sudlow C. Stroke prevention. Clin Evid. 2003 Dec;(10):246-72. Review. Update in: Clin Evid. 2004 Dec;(12):253-84. PubMed PMID: 15555091. 1018: Freestone B, Lip GY. Atrial fibrillation (acute). Clin Evid. 2003 Dec;(10):76-94. Review. Update in: Clin Evid. 2004 Jun;(11):76-97. PubMed PMID: 15555087. 1019: Lip PL, Chatterjee S, Caine GJ, Hope-Ross M, Gibson J, Blann AD, Lip GY. Plasma vascular endothelial growth factor, angiopoietin-2, and soluble 133 angiopoietin receptor tie-2 in diabetic retinopathy: effects of laser photocoagulation and angiotensin receptor blockade. Br J Ophthalmol. 2004 Dec;88(12):1543-6. PubMed PMID: 15548809; PubMed Central PMCID: PMC1772428. 1020: Hamaad A, Lip GY, MacFadyen RJ. Acute coronary syndromes presenting solely with heart failure symptoms: are they under recognised? Eur J Heart Fail. 2004 Oct;6(6):683-6. PubMed PMID: 15542402. 1021: Connolly DL, Lip GY, Lo TS. Pushing the envelope too far? J Am Coll Cardiol. 2004 Nov 16;44(10):2094-5; author reply 2095. PubMed PMID: 15542300. 1022: Lim HS, Lip GY, Blann AD. Plasma von Willebrand factor and the development of the metabolic syndrome in patients with hypertension. J Clin Endocrinol Metab. 2004 Nov;89(11):5377-81. PubMed PMID: 15531484. 1023: Nadar S, Blann AD, Lip GY. Platelet morphology and plasma indices of platelet activation in essential hypertension: effects of amlodipine-based antihypertensive therapy. Ann Med. 2004;36(7):552-7. PubMed PMID: 15513305. 1024: Hamaad A, Lip GY, MacFadyen RJ. Heart rate variability estimates of autonomic tone: relationship to mapping pathological and procedural stress responses in coronary disease. Ann Med. 2004;36(6):448-61. Review. PubMed PMID: 15513296. 1025: Hoar FJ, Lip GY, Belgore F, Stonelake PS. Circulating levels of VEGF-A, VEGF-D and soluble VEGF-A receptor (sFIt-1) in human breast cancer. Int J Biol Markers. 2004 Jul-Sep;19(3):229-35. PubMed PMID: 15503825. 1026: Nadar S, Beevers DG, Lip GY. Echocardiographic changes in patients with malignant phase hypertension: the West Birmingham Malignant Hypertension Register. J Hum Hypertens. 2005 Jan;19(1):69-75. PubMed PMID: 15457204. 1027: Conway DS, Lip GY. Inflammation, arrhythmia burden and the thrombotic consequences of atrial fibrillation. Eur Heart J. 2004 Oct;25(19):1761. PubMed PMID: 15451156. 1028: Conway DS, Buggins P, Hughes E, Lip GY. Prognostic significance of raised 134 plasma levels of interleukin-6 and C-reactive protein in atrial fibrillation. Am Heart J. 2004 Sep;148(3):462-6. PubMed PMID: 15389233. 1029: Clagett GP, Sobel M, Jackson MR, Lip GY, Tangelder M, Verhaeghe R. Antithrombotic therapy in peripheral arterial occlusive disease: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy. Chest. 2004 Sep;126(3 Suppl):609S-626S. Review. PubMed PMID: 15383487. 1030: Lee KW, Lip GY, Tayebjee M, Foster W, Blann AD. Circulating endothelial cells, von Willebrand factor, interleukin-6, and prognosis in patients with acute coronary syndromes. Blood. 2005 Jan 15;105(2):526-32. Epub 2004 Sep 16. PubMed PMID: 15374879. 1031: Marín F, Roldán V, Climent VE, Ibáñez A, García A, Marco P, Sogorb F, Lip GY. Plasma von Willebrand factor, soluble thrombomodulin, and fibrin D-dimer concentrations in acute onset non-rheumatic atrial fibrillation. Heart. 2004 Oct;90(10):1162-6. PubMed PMID: 15367514; PubMed Central PMCID: PMC1768504. 1032: Nadar SK, Blann AD, Lip GY. Plasma and platelet-derived vascular endothelial growth factor and angiopoietin-1 in hypertension: effects of antihypertensive therapy. J Intern Med. 2004 Oct;256(4):331-7. PubMed PMID: 15367176. 1033: Freestone B, Kamath S, Lip G. Atrial fibrillation (acute). Clin Evid. 2003 Jun;(9):61-71. Review. Update in: Clin Evid. 2003 Dec;(10):76-94. PubMed PMID: 15366136. 1034: Chong AY, Blann AD, Patel J, Freestone B, Hughes E, Lip GY. Endothelial dysfunction and damage in congestive heart failure: relation of flow-mediated dilation to circulating endothelial cells, plasma indexes of endothelial damage, and brain natriuretic peptide. Circulation. 2004 Sep 28;110(13):1794-8. Epub 2004 Sep 13. PubMed PMID: 15364797. 1035: Lim HS, MacFadyen RJ, Lip GY. Diabetes mellitus, the renin-angiotensin-aldosterone system, and the heart. Arch Intern Med. 2004 Sep 13;164(16):1737-48. Review. PubMed PMID: 15364666. 1036: Tayebjee MH, Nadar SK, MacFadyen RJ, Lip GY. Tissue inhibitor of 135 metalloproteinase-1 and matrix metalloproteinase-9 levels in patients with hypertension Relationship to tissue Doppler indices of diastolic relaxation. Am J Hypertens. 2004 Sep;17(9):770-4. PubMed PMID: 15363818. 1037: Tayebjee MH, Nadar S, Blann AD, Gareth Beevers D, MacFadyen RJ, Lip GY. Matrix metalloproteinase-9 and tissue inhibitor of metalloproteinase-1 in hypertension and their relationship to cardiovascular risk and treatment: a substudy of the Anglo-Scandinavian Cardiac Outcomes Trial (ASCOT). Am J Hypertens. 2004 Sep;17(9):764-9. PubMed PMID: 15363817. 1038: Marín F, Corral J, Roldán V, González-Conejero R, del Rey ML, Sogorb F, Lip GY, Vicente V. Factor XIII Val34Leu polymorphism modulates the prothrombotic and inflammatory state associated with atrial fibrillation. J Mol Cell Cardiol. 2004 Sep;37(3):699-704. PubMed PMID: 15350843. 1039: Conway DS, Buggins P, Hughes E, Lip GY. Predictive value of indexes of inflammation and hypercoagulability on success of cardioversion of persistent atrial fibrillation. Am J Cardiol. 2004 Aug 15;94(4):508-10. PubMed PMID: 15325942. 1040: Lim HS, Lip GY. Diabetes, the renin-angiotensin system and heart disease. Curr Vasc Pharmacol. 2003 Jun;1(2):225-38. Review. PubMed PMID: 15320846. 1041: Tan KT, Watson SP, Lip GY. The endothelium and platelets in cardiovascular disease: potential targets for therapeutic intervention. Curr Med Chem Cardiovasc Hematol Agents. 2004 Apr;2(2):169-78. Review. PubMed PMID: 15320799. 1042: Choudhury A, Lip GY. Left ventricular systolic dysfunction and atrial fibrillation in older people in the community: the need for identification, as well as appropriate management. Age Ageing. 2004 Sep;33(5):434-6. PubMed PMID: 15315915. 1043: Lim HS, Hamaad A, Lip GY. Clinical review: clinical management of atrial fibrillation - rate control versus rhythm control. Crit Care. 2004 Aug;8(4):271-9. Epub 2004 Feb 19. Review. PubMed PMID: 15312210; PubMed Central PMCID: PMC522829. 1044: Caine GJ, Nadar SK, Lip GY, Stonelake PS, Blann AD. Platelet adhesion in 136 breast cancer: development and application of a novel assay. Blood Coagul Fibrinolysis. 2004 Sep;15(6):513-8. PubMed PMID: 15311162. 1045: Lip GY, Khan H, Bhatnagar A, Brahmabhatt N, Crook P, Davies MK; West Birmingham heart failure project. Ethnic differences in patient perceptions of heart failure and treatment: the West Birmingham heart failure project. Heart. 2004 Sep;90(9):1016-9. PubMed PMID: 15310689; PubMed Central PMCID: PMC1768414. 1046: Tayebjee MH, Lip GY, MacFadyen RJ. The unifying role of matrix metalloproteinases in atheroma and vascular stroke. Stroke. 2004 Oct;35(10):2239. Epub 2004 Aug 12. PubMed PMID: 15308790. 1047: Lee KW, Hamaad A, MacFadyen RJ, Lip GY. Effects of dietary fat intake in sudden death: reduction of death with omega-3 fatty acids. Curr Cardiol Rep. 2004 Sep;6(5):371-8. Review. PubMed PMID: 15306094. 1048: Lee KW, Lip GY, Blann AD. Plasma angiopoietin-1, angiopoietin-2, angiopoietin receptor tie-2, and vascular endothelial growth factor levels in acute coronary syndromes. Circulation. 2004 Oct 19;110(16):2355-60. Epub 2004 Aug 9. PubMed PMID: 15302795. 1049: Sosin MD, Bhatia GS, Zarifis J, Davis RC, Lip GY. An 8-year follow-up study of acute admissions with heart failure in a multiethnic population. Eur J Heart Fail. 2004 Aug;6(5):669-72. PubMed PMID: 15302017. 1050: Swancutt D, Hobbs R, Fitzmaurice D, Mant J, Murray E, Jowett S, Raftery J, Bryan S, Davies M, Lip G. A randomised controlled trial and cost effectiveness study of systematic screening (targeted and total population screening) versus routine practice for the detection of atrial fibrillation in the over 65s: (SAFE) [ISRCTN19633732]. BMC Cardiovasc Disord. 2004 Jul 29;4:12. PubMed PMID: 15283871; PubMed Central PMCID: PMC509245. 1051: Tayebjee MH, Lim HS, MacFadyen RJ, Lip GY. Matrix metalloproteinase-9 and tissue inhibitor of metalloproteinase-1 and -2 in type 2 diabetes: effect of 1 year's cardiovascular risk reduction therapy. Diabetes Care. 2004 Aug;27(8):2049-51. PubMed PMID: 15277439. 1052: Lim HS, Patel JV, Lip GY. Metabolic syndrome: a definition in progress. 137 Circulation. 2004 Jul 27;110(4):e35; author reply e35. PubMed PMID: 15277336. 1053: Lip GY, Felmeden DC. Antiplatelet agents and anticoagulants for hypertension. Cochrane Database Syst Rev. 2004;(3):CD003186. Review. Update in: Cochrane Database Syst Rev. 2011;(12):CD003186. PubMed PMID: 15266473. 1054: Goyal D, Choudhary A, Lip GY, MacFadyen RJ. Diastolic heart failure: recognition, diagnosis and management. Expert Opin Pharmacother. 2004 Aug;5(8):1745-54. Review. PubMed PMID: 15264989. 1055: Nadar SK, Blann AD, Kamath S, Beevers DG, Lip GY. Platelet indexes in relation to target organ damage in high-risk hypertensive patients: a substudy of the Anglo-Scandinavian Cardiac Outcomes Trial (ASCOT). J Am Coll Cardiol. 2004 Jul 21;44(2):415-22. PubMed PMID: 15261941. 1056: Beevers DG, Lip GY, Blann AD. Salt intake and Helicobacter pylori infection. J Hypertens. 2004 Aug;22(8):1475-7. PubMed PMID: 15257168. 1057: Caine GJ, Lip GY, Blann AD. Platelet-derived VEGF, Flt-1, angiopoietin-1 and P-selectin in breast and prostate cancer: further evidence for a role of platelets in tumour angiogenesis. Ann Med. 2004;36(4):273-7. PubMed PMID: 15224653. 1058: Gubitz G, Lip G, Sudlow C, Sandercock P. [Stroke: secondary prevention]. Vasa. 2004 May;33(2):110-3; discussion 114. Review. German. PubMed PMID: 15224467. 1059: Chung NA, Beevers DG, Lip G. Effects of losartan versus hydrochlorothiazide on indices of endothelial damage/dysfunction, angiogenesis and tissue factor in essential hypertension. Blood Press. 2004;13(3):183-9. PubMed PMID: 15223728. 1060: Caine GJ, Lip GY, Stonelake PS, Ryan P, Blann AD. Platelet activation, coagulation and angiogenesis in breast and prostate carcinoma. Thromb Haemost. 2004 Jul;92(1):185-90. PubMed PMID: 15213860. 1061: Choudhury A, Lip GY. Antiarrhythmic drugs in atrial fibrillation: an overview of new agents, their mechanisms of action and potential clinical 138 utility. Expert Opin Investig Drugs. 2004 Jul;13(7):841-55. Review. PubMed PMID: 15212622. 1062: Tayebjee MH, Singh SP, Lip GY. Autonomic reflexes in heterotopic heart transplantation. Int J Clin Pract. 2004 May;58(5):520-2. PubMed PMID: 15206511. 1063: Conway DS, Lip GY. Further insights into the prothrombotic state in mitral stenosis and atrial flutter. Chest. 2004 Jun;125(6):2361-2; author reply 2362-3. PubMed PMID: 15189964. 1064: Conway DS, Buggins P, Hughes E, Lip GY. Relationship of interleukin-6 and C-reactive protein to the prothrombotic state in chronic atrial fibrillation. J Am Coll Cardiol. 2004 Jun 2;43(11):2075-82. PubMed PMID: 15172416. 1065: Conway DS, Lip GY. Comparison of outcomes of patients with symptomatic peripheral artery disease with and without atrial fibrillation (the West Birmingham Atrial Fibrillation Project). Am J Cardiol. 2004 Jun 1;93(11):1422-5, A10. PubMed PMID: 15165931. 1066: Conway DS, Buggins P, Hughes E, Lip GY. Relation of interleukin-6, C-reactive protein, and the prothrombotic state to transesophageal echocardiographic findings in atrial fibrillation. Am J Cardiol. 2004 Jun 1;93(11):1368-73, A6. PubMed PMID: 15165916. 1067: Nadar S, Lip GY. Platelet activation in the hypertensive disorders of pregnancy. Expert Opin Investig Drugs. 2004 May;13(5):523-9. Review. PubMed PMID: 15155127. 1068: Lim HS, Blann AD, Lip GY. Soluble CD40 ligand, soluble P-selectin, interleukin-6, and tissue factor in diabetes mellitus: relationships to cardiovascular disease and risk factor intervention. Circulation. 2004 Jun 1;109(21):2524-8. Epub 2004 May 10. PubMed PMID: 15136493. 1069: Lane D, Lip GY, Carroll D. Is depression following acute myocardial infarction an independent risk for mortality? Am J Cardiol. 2004 May 15;93(10):1333-4. PubMed PMID: 15135723. 139 1070: Lip GY, Blann AD. Thrombogenesis, atherogenesis and angiogenesis in vascular disease: a new 'vascular triad'. Ann Med. 2004;36(2):119-25. Review. PubMed PMID: 15119831. 1071: Nadar SK, Al Yemeni E, Blann AD, Lip GY. Thrombomodulin, von Willebrand factor and E-selectin as plasma markers of endothelial damage/dysfunction and activation in pregnancy induced hypertension. Thromb Res. 2004;113(2):123-8. PubMed PMID: 15115667. 1072: Dretzke J, Toff WD, Lip GY, Raftery J, Fry-Smith A, Taylor R. Dual chamber versus single chamber ventricular pacemakers for sick sinus syndrome and atrioventricular block. Cochrane Database Syst Rev. 2004;(2):CD003710. Review. PubMed PMID: 15106214. 1073: Tayebjee MH, Lip GY, MacFadyen RJ. Collateralization and the response to obstruction of epicardial coronary arteries. QJM. 2004 May;97(5):259-72. Review. PubMed PMID: 15100419. 1074: Spencer CG, Martin SC, Felmeden DC, Blann AD, Beevers GD, Lip GY. Relationship of homocysteine to markers of platelet and endothelial activation in "high risk" hypertensives: a substudy of the Anglo-Scandinavian Cardiac Outcomes Trial. Int J Cardiol. 2004 Apr;94(2-3):293-300. PubMed PMID: 15093996. 1075: Spencer CG, Beevers DG, Lip GY. Ethnic differences in left ventricular size and the prevalence of left ventricular hypertrophy among hypertensive patients vary with electrocardiographic criteria. J Hum Hypertens. 2004 Sep;18(9):631-6. PubMed PMID: 15071486. 1076: Tan KT, Lip GY. Atrial fibrillation: should we target platelets or the coagulation pathway? Card Electrophysiol Rev. 2003 Dec;7(4):370-1. Review. PubMed PMID: 15071256. 1077: Lim HS, Lip GY. Impaired fasting glycaemia vs. impaired glucose tolerance: two sides of the same coin with implications for cardiovascular risk. Diabet Med. 2004 Apr;21(4):303-4. PubMed PMID: 15049929. 1078: Makin AJ, Blann AD, Chung NA, Silverman SH, Lip GY. Assessment of endothelial damage in atherosclerotic vascular disease by quantification of 140 circulating endothelial cells. Relationship with von Willebrand factor and tissue factor. Eur Heart J. 2004 Mar;25(5):371-6. PubMed PMID: 15033248. 1079: Thrall G, Lip GY, Lane D. Compliance with pharmacological therapy in hypertension: can we do better, and how? J Hum Hypertens. 2004 Sep;18(9):595-7. PubMed PMID: 15029219. 1080: Connolly DL, Choudhury A, Davis RC, Lip GY. A randomized trial of aspirin on the risk of embolic events in patients with infective endocarditis. J Am Coll Cardiol. 2004 Mar 17;43(6):1134-5; author reply 1135. PubMed PMID: 15028387. 1081: Lee KW, Lip GY. Acute versus habitual exercise, thrombogenesis and exercise intensity. Thromb Haemost. 2004 Mar;91(3):416-9. PubMed PMID: 15025076. 1082: Chong AY, Caine GJ, Freestone B, Blann AD, Lip GY. Plasma angiopoietin-1, angiopoietin-2, and angiopoietin receptor tie-2 levels in congestive heart failure. J Am Coll Cardiol. 2004 Feb 4;43(3):423-8. PubMed PMID: 15013125. 1083: Foster W, Lip GY. Hormone replacement therapy and cardiovascular disease: does route of administration and formulation matter? Br J Haematol. 2004 Mar;124(6):836-40. PubMed PMID: 15009073. 1084: Tan KT, Lip GY. Current anticoagulation therapy--a GP guide. Practitioner. 2004 Feb;248(1655):87-8, 92-4, 97-8. PubMed PMID: 15008109. 1085: Freestone B, Lip GY. Tedisamil: a new novel antiarrhythmic. Expert Opin Investig Drugs. 2004 Feb;13(2):151-60. PubMed PMID: 14996649. 1086: Belgore F, Blann A, Neil D, Ahmed AS, Lip GY. Localisation of members of the vascular endothelial growth factor (VEGF) family and their receptors in human atherosclerotic arteries. J Clin Pathol. 2004 Mar;57(3):266-72. PubMed PMID: 14990597; PubMed Central PMCID: PMC1770244. 1087: Lim HS, Lip GY. Arterial stiffness in diabetes and hypertension. J Hum Hypertens. 2004 Jul;18(7):467-8. Review. PubMed PMID: 14985778. 141 1088: Chong AY, Caine GJ, Lip GY. Angiopoietin/tie-2 as mediators of angiogenesis: a role in congestive heart failure? Eur J Clin Invest. 2004 Jan;34(1):9-13. PubMed PMID: 14984432. 1089: Brotman DJ, Deitcher SR, Lip GY, Matzdorff AC. Virchow's triad revisited. South Med J. 2004 Feb;97(2):213-4. PubMed PMID: 14982286. 1090: Freestone B, Beevers DG, Lip GY. The renin-angiotensin-aldosterone system in atrial fibrillation: a new therapeutic target? J Hum Hypertens. 2004 Jul;18(7):461-5. Review. PubMed PMID: 14973520. 1091: Bacon SL, Ring C, Lip GY, Carroll D. Increases in lipids and immune cells in response to exercise and mental stress in patients with suspected coronary artery disease: effects of adjustment for shifts in plasma volume. Biol Psychol. 2004 Feb;65(3):237-50. PubMed PMID: 14757310. 1092: Landray MJ, Wheeler DC, Lip GY, Newman DJ, Blann AD, McGlynn FJ, Ball S, Townend JN, Baigent C. Inflammation, endothelial dysfunction, and platelet activation in patients with chronic kidney disease: the chronic renal impairment in Birmingham (CRIB) study. Am J Kidney Dis. 2004 Feb;43(2):244-53. PubMed PMID: 14750089. 1093: Chung NA, Beevers DG, Lip GY. Management of hypertension in pregnancy. Am J Cardiovasc Drugs. 2001;1(4):253-62. Review. PubMed PMID: 14728025. 1094: Marín F, Roldán V, Climent V, Lip GY. Matrix metalloproteinases in atrial fibrillation. J Am Coll Cardiol. 2004 Jan 7;43(1):152; author reply 152-3. PubMed PMID: 14715200. 1095: Hamaad A, Lip GY, MacFadyen RJ. Unheralded sudden cardiac death: do autonomic tone and thrombosis interact as key factors in aetiology? Ann Med. 2003;35(8):592-604. Review. PubMed PMID: 14708969. 1096: Chung I, Lip GY. White coat hypertension: not so benign after all? J Hum Hypertens. 2003 Dec;17(12):807-9. PubMed PMID: 14704723. 1097: Makin AJ, Chung NA, Silverman SH, Lip GY. Thrombogenesis and endothelial 142 damage/dysfunction in peripheral artery disease. Relationship to ethnicity and disease severity. Thromb Res. 2003;111(4-5):221-6. PubMed PMID: 14693167. 1098: Spencer CG, Gurney D, Felmeden DC, Blann AD, Beevers DG, Lip GY. Platelet and haemorheological markers in 'high risk' hypertensives are improved by tighter blood pressure control and cardiovascular risk management: a substudy of the Anglo-Scandinavian Cardiac Outcomes Trial (ASCOT). J Intern Med. 2004 Jan;255(1):59-67. PubMed PMID: 14687239. 1099: Sosin M, Davis RC, Lip GY. Mortality in congestive heart failure complicated by atrial fibrillation. Eur Heart J. 2004 Jan;25(1):97-8; author reply 98. PubMed PMID: 14683750. 1100: Lip GY. The prothrombotic state in atrial fibrillation: the atrium, the endothelium... And tissue factor? Thromb Res. 2003;111(3):133-5. PubMed PMID: 14678809. 1101: Conway DS, Lip GY. Ethnicity in relation to atrial fibrillation and stroke (the West Birmingham Stroke Project). Am J Cardiol. 2003 Dec 15;92(12):1476-9. PubMed PMID: 14675592. 1102: Lim HS, Lip GY. Is angiotensin receptor blockade antithrombotic? Arch Intern Med. 2003 Dec 8-22;163(22):2790-1; author reply 2792-3. PubMed PMID: 14662638. 1103: Alfonso F, Tayebjee MH, Lip GY. Restenosis after coronary stenting: the 'gender paradox'. Eur Heart J. 2003 Dec;24(24):2239. PubMed PMID: 14659777. 1104: Blann AD, Nadar SK, Lip GY. The adhesion molecule P-selectin and cardiovascular disease. Eur Heart J. 2003 Dec;24(24):2166-79. Review. Erratum in: Eur Heart J. 2006 Feb;27(4):501. PubMed PMID: 14659768. 1105: Tayebjee MH, MacFadyen RJ, Lip GY. Extracellular matrix biology: a new frontier in linking the pathology and therapy of hypertension? J Hypertens. 2003 Dec;21(12):2211-8. Review. PubMed PMID: 14654734. 1106: Roldán V, Marín F, Lip GY, Blann AD. Soluble E-selectin in cardiovascular 143 disease and its risk factors. A review of the literature. Thromb Haemost. 2003 Dec;90(6):1007-20. Review. PubMed PMID: 14652631. 1107: Tayebjee MH, Lip GY. Psychosocial functioning of adults with congenital heart disease: a neglected area. Eur Heart J. 2003 Dec;24(23):2159; author reply 2159-60. PubMed PMID: 14643278. 1108: Lane D, Carroll D, Lip GY. Anxiety, depression, and prognosis after myocardial infarction: is there a causal association? J Am Coll Cardiol. 2003 Nov 19;42(10):1808-10. PubMed PMID: 14642692. 1109: Sosin MD, Bhatia G, Davis RC, Lip GY. Congestive heart failure and Virchow's triad: a neglected association. Wien Med Wochenschr. 2003;153(19-20):411-6. Review. PubMed PMID: 14648920. 1110: Chin BS, Blann AD, Gibbs CR, Chung NA, Conway DG, Lip GY. Prognostic value of interleukin-6, plasma viscosity, fibrinogen, von Willebrand factor, tissue factor and vascular endothelial growth factor levels in congestive heart failure. Eur J Clin Invest. 2003 Nov;33(11):941-8. PubMed PMID: 14636296. 1111: Makin AJ, Chung NA, Silverman SH, Moss MS, Lip GY. Indices of thrombogenesis, endothelial damage and platelet function following percutaneous peripheral artery angiography and angioplasty for peripheral vascular disease. Pathophysiol Haemost Thromb. 2003 Mar-Apr;33(2):102-8. PubMed PMID: 14624052. 1112: Chung NA, Lydakis C, Belgore F, Li-Saw-Hee FL, Blann AD, Lip GY. Angiogenesis, thrombogenesis, endothelial dysfunction and angiographic severity of coronary artery disease. Heart. 2003 Dec;89(12):1411-5. PubMed PMID: 14617549; PubMed Central PMCID: PMC1767979. 1113: Pfeffer MA, McMurray JJ, Velazquez EJ, Rouleau JL, Køber L, Maggioni AP, Solomon SD, Swedberg K, Van de Werf F, White H, Leimberger JD, Henis M, Edwards S, Zelenkofske S, Sellers MA, Califf RM; Valsartan in Acute Myocardial Infarction Trial Investigators. Valsartan, captopril, or both in myocardial infarction complicated by heart failure, left ventricular dysfunction, or both. N Engl J Med. 2003 Nov 13;349(20):1893-906. Epub 2003 Nov 10. Erratum in: N Engl J Med. 2004 Jan 8;350(2):203. PubMed PMID: 14610160. 144 1114: Tan KT, Lip GY. Red vs white thrombi: treating the right clot is crucial. Arch Intern Med. 2003 Nov 10;163(20):2534-5; author reply 2535. PubMed PMID: 14609795. 1115: Lane D, Carroll D, Ring C, Beevers DG, Lip GY. The prevalence and persistence of depression and anxiety following myocardial infarction. Br J Health Psychol. 2002 Feb;7(Pt 1):11-21. PubMed PMID: 14596714. 1116: Chong AY, Lip GY. LIFE: losartan versus atenolol. Lancet. 2003 Oct 25;362(9393):1416. PubMed PMID: 14585648. 1117: Tan KT, Lip GY. Platelets, atherosclerosis and the endothelium: new therapeutic targets? Expert Opin Investig Drugs. 2003 Nov;12(11):1765-76. Review. PubMed PMID: 14585053. 1118: Lip GY, Makin AJ. Treatment of hypertension in peripheral arterial disease. Cochrane Database Syst Rev. 2003;(4):CD003075. Review. Update in: Cochrane Database Syst Rev. 2009;(4):CD003075. PubMed PMID: 14583959. 1119: Lee KW, Lip GY. Effects of lifestyle on hemostasis, fibrinolysis, and platelet reactivity: a systematic review. Arch Intern Med. 2003 Oct 27;163(19):2368-92. Review. PubMed PMID: 14581258. 1120: Lip GY, Beevers DG. More evidence on blocking the renin-angiotensin-aldosterone system in cardiovascular disease and the long-term treatment of hypertension: data from recent clinical trials (CHARM, EUROPA, ValHEFT, HOPE-TOO and SYST-EUR2). J Hum Hypertens. 2003 Nov;17(11):747-50. Review. PubMed PMID: 14578913. 1121: Freestone B, Rajaratnam R, Hussain N, Lip GY. Admissions with atrial fibrillation in a multiracial population in Kuala Lumpur, Malaysia. Int J Cardiol. 2003 Oct;91(2-3):233-8. PubMed PMID: 14559136. 1122: Caine GJ, Stonelake PS, Rea D, Lip GY. Coagulopathic complications in breast cancer. Cancer. 2003 Oct 15;98(8):1578-86. Review. PubMed PMID: 14534872. 1123: Lee KW, Lip GY. Acute coronary syndromes: Virchow's triad revisited. Blood 145 Coagul Fibrinolysis. 2003 Oct;14(7):605-25. Review. PubMed PMID: 14517485. 1124: Caine GJ, Lip GY. Thromboembolism associated with new anti-cancer treatment strategies in combination with conventional chemotherapy: new drugs, old risks? Thromb Haemost. 2003 Oct;90(4):567-9. PubMed PMID: 14515174. 1125: Caine GJ, Blann AD, Stonelake PS, Ryan P, Lip GY. Plasma angiopoietin-1, angiopoietin-2 and Tie-2 in breast and prostate cancer: a comparison with VEGF and Flt-1. Eur J Clin Invest. 2003 Oct;33(10):883-90. PubMed PMID: 14511360. 1126: Belgore F, Lip GY, Blann AD. Basic fibrobrast growth factor induces the secretion of vascular endothelial growth factor by human aortic smooth muscle cells but not by endothelial cells. Eur J Clin Invest. 2003 Oct;33(10):833-9. PubMed PMID: 14511353. 1127: Nadar S, Lip GY, Beevers DG. Primary hyperaldosteronism. Ann Clin Biochem. 2003 Sep;40(Pt 5):439-52. Review. PubMed PMID: 14503982. 1128: Kamath S, Lip GY. Fibrinogen: biochemistry, epidemiology and determinants. QJM. 2003 Oct;96(10):711-29. Review. PubMed PMID: 14500858. 1129: Sosin MD, Bhatia GS, Davis RC, Connolly DL, Lip GY. Heart failure: treatment and ethnic origin. Lancet. 2003 Sep 13;362(9387):919-20. PubMed PMID: 13678991. 1130: Jolly K, Lip GY, Sandercock J, Greenfield SM, Raftery JP, Mant J, Taylor R, Lane D, Lee KW, Stevens AJ. Home-based versus hospital-based cardiac rehabilitation after myocardial infarction or revascularisation: design and rationale of the Birmingham Rehabilitation Uptake Maximisation Study (BRUM): a randomised controlled trial [ISRCTN72884263]. BMC Cardiovasc Disord. 2003 Sep 10;3:10. Epub 2003 Sep 10. PubMed PMID: 12964946; PubMed Central PMCID: PMC200974. 1131: Chin BS, Conway DS, Chung NA, Blann AD, Gibbs CR, Lip GY. Interleukin-6, tissue factor and von Willebrand factor in acute decompensated heart failure: relationship to treatment and prognosis. Blood Coagul Fibrinolysis. 2003 Sep;14(6):515-21. PubMed PMID: 12960603. 146 1132: Blann AD, Lip GY. Effects of C-reactive protein on the release of von Willebrand factor, E-selectin, thrombomodulin and intercellular adhesion molecule-1 from human umbilical vein endothelial cells. Blood Coagul Fibrinolysis. 2003 Jun;14(4):335-40. PubMed PMID: 12945874. 1133: Mant JW, Richards SH, Hobbs FD, Fitzmaurice D, Lip GY, Murray E, Banting M, Fletcher K, Rahman J, Allan T, Raftery J, Bryan S; Midlands Research Consortium of General Practice. Protocol for Birmingham Atrial Fibrillation Treatment of the Aged study (BAFTA): a randomised controlled trial of warfarin versus aspirin for stroke prevention in the management of atrial fibrillation in an elderly primary care population [ISRCTN89345269]. BMC Cardiovasc Disord. 2003 Aug 26;3:9. Epub 2003 Aug 26. PubMed PMID: 12939169; PubMed Central PMCID: PMC201020. 1134: Nadar S, Lip GY. Homocysteine and the risk of stroke and thromboembolism in atrial fibrillation: an uncertain role. Stroke. 2003 Sep;34(9):e143; author reply e143-5. Epub 2003 Aug 21. PubMed PMID: 12933971. 1135: Kamath S, Blann AD, Chin BS, Lip GY. Platelet activation, haemorheology and thrombogenesis in acute atrial fibrillation: a comparison with permanent atrial fibrillation. Heart. 2003 Sep;89(9):1093-5. PubMed PMID: 12923042; PubMed Central PMCID: PMC1767809. 1136: Chong AY, Rajaratnam R, Hussein NR, Lip GY. Heart failure in a multiethnic population in Kuala Lumpur, Malaysia. Eur J Heart Fail. 2003 Aug;5(4):569-74. PubMed PMID: 12921820. 1137: Lip GY, Lane DA, Millane TA, Tayebjee MH. Psychological interventions for depression in adolescent and adult congenital heart disease. Cochrane Database Syst Rev. 2003;(3):CD004394. Review. PubMed PMID: 12918013. 1138: Felmeden DC, Spencer CG, Chung NA, Belgore FM, Blann AD, Beevers DG, Lip GY. Relation of thrombogenesis in systemic hypertension to angiogenesis and endothelial damage/dysfunction (a substudy of the Anglo-Scandinavian Cardiac Outcomes Trial [ASCOT]). Am J Cardiol. 2003 Aug 15;92(4):400-5. PubMed PMID: 12914869. 1139: Lee KW, Lip GY. The role of omega-3 fatty acids in the secondary prevention of cardiovascular disease. QJM. 2003 Jul;96(7):465-80. Review. PubMed PMID: 147 12881589. 1140: Roldán V, Marín F, Blann AD, García A, Marco P, Sogorb F, Lip GY. Interleukin-6, endothelial activation and thrombogenesis in chronic atrial fibrillation. Eur Heart J. 2003 Jul;24(14):1373-80. PubMed PMID: 12871695. 1141: Nadar S, Lip GY. The prothrombotic state in hypertension and the effects of antihypertensive treatment. Curr Pharm Des. 2003;9(21):1715-32. Review. PubMed PMID: 12871204. 1142: MacFadyen RJ, Lip GY, Davis R. Hypertension to heart failure: new developmental strategies do not cross a clinical and therapeutic divide. Curr Pharm Des. 2003;9(21):1665-78. Review. PubMed PMID: 12871200. 1143: Nadar S, Blann A, Lip GY. Homocysteine is unlikely to be associated with the risk of thromboembolic complications in atrial fibrillation. Blood Coagul Fibrinolysis. 2003 Jul;14(5):513-4. PubMed PMID: 12851541. 1144: Felmeden DC, Blann AD, Spencer CG, Beevers DG, Lip GY. A comparison of flow-mediated dilatation and von Willebrand factor as markers of endothelial cell function in health and in hypertension: relationship to cardiovascular risk and effects of treatment: a substudy of the Anglo-Scandinavian Cardiac Outcomes Trial. Blood Coagul Fibrinolysis. 2003 Jul;14(5):425-31. PubMed PMID: 12851527. 1145: Tayebjee MH, Lip GY. Fibrin D-dimer levels in atrial fibrillation as an index of thrombogenesis: a possible test to exclude left atrial thrombus? Am J Cardiol. 2003 Jul 1;92(1):47-9. PubMed PMID: 12842244. 1146: Chin BS, Gibbs CR, Blann AD, Lip GY. Neither carvedilol nor bisoprolol in maximally tolerated doses has any specific advantage in lowering chronic heart failure oxidant stress: implications for beta-blocker selection. Clin Sci (Lond). 2003 Oct;105(4):507-12. PubMed PMID: 12841846. 1147: Marín F, Roldán V, Lip GY. Fibrinolytic function and atrial fibrillation. Thromb Res. 2003 Mar 15;109(5-6):233-40. Review. PubMed PMID: 12818244. 1148: Tayebjee MH, Lee KW, Lip GY. Salt-loading and nitric oxide inhibition after 148 the menopause. J Hypertens. 2003 Jul;21(7):1255-7. Review. PubMed PMID: 12817168. 1149: Chung NA, Makin AJ, Lip GY. Measurement of the soluble angiopoietin receptor tie-2 in patients with coronary artery disease: development and application of an immunoassay. Eur J Clin Invest. 2003 Jul;33(7):529-35. PubMed PMID: 12814387. 1150: Conway DS, Pearce LA, Chin BS, Hart RG, Lip GY. Prognostic value of plasma von Willebrand factor and soluble P-selectin as indices of endothelial damage and platelet activation in 994 patients with nonvalvular atrial fibrillation. Circulation. 2003 Jul 1;107(25):3141-5. Epub 2003 Jun 9. PubMed PMID: 12796127. 1151: Tan KT, Lip GY, Blann AD. Post-stroke inflammatory response: effects of stroke evolution and outcome. Curr Atheroscler Rep. 2003 Jul;5(4):245-51. Review. PubMed PMID: 12793964. 1152: Blann AD, Nadar S, Lip GY. Pharmacological modulation of platelet function in hypertension. Hypertension. 2003 Jul;42(1):1-7. Epub 2003 Jun 2. Review. PubMed PMID: 12782643. 1153: Caine GJ, Lip GY. Is low-molecular-weight heparin safer than warfarin for secondary prevention of venous thromboembolism in cancer patients? Arch Intern Med. 2003 May 26;163(10):1243-4; author reply 1244. PubMed PMID: 12767973. 1154: Nadar S, Lip GY. Hypertension and the prothrombotic state. J Am Coll Cardiol. 2003 May 21;41(10):1847; author reply 1847. PubMed PMID: 12767675. 1155: Freestone B, Lip GY. Ethnicity and arrhythmias. Card Electrophysiol Rev. 2003 Jan;7(1):92-5. Review. PubMed PMID: 12766528. 1156: Beevers DG, Lee KW, Lip GY. The Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT): ALL predictable, and no big surprise out of a HAT? J Hum Hypertens. 2003 Jun;17(6):367-72. PubMed PMID: 12764397. 1157: Makin AJ, Chung NA, Silverman SH, Lip GY. Alterations of thrombogenesis, endothelial damage and oxidative stress with reperfusion during femoral artery 149 bypass surgery for peripheral vascular disease. Pathophysiol Haemost Thromb. 2002 Jul-Aug;32(4):158-64. PubMed PMID: 12759516. 1158: Lee KW, Lip GY. Insulin resistance and vascular remodelling, in relation to left ventricular mass, geometry and function: an answer to LIFE? J Hum Hypertens. 2003 May;17(5):299-304. PubMed PMID: 12756401. 1159: Caine GJ, Lip GY. Validity of D-dimer tests for pulmonary embolism: better to diagnose or exclude? Ann Emerg Med. 2003 May;41(5):756; author reply 756-7. PubMed PMID: 12744250. 1160: Hamaad A, Lip GY. Intravenous water-soluble amiodarone improved 24-hour survival in incessant ventricular tachycardia. ACP J Club. 2003 May-Jun;138(3):62. PubMed PMID: 12725617. 1161: Nadar S, Lim HS, Lip GY. Implications of the LIFE trial. Expert Opin Investig Drugs. 2003 May;12(5):871-7. Review. PubMed PMID: 12720497. 1162: Hamaad A, Tayebjee MH, Lip GY. The METHRO trials. Expert Opin Investig Drugs. 2003 May;12(5):865-70. Review. PubMed PMID: 12720496. 1163: Tan KT, Makin A, Lip GY. Factor X inhibitors. Expert Opin Investig Drugs. 2003 May;12(5):799-804. Review. PubMed PMID: 12720491. 1164: Lim HS, Lip GY. Casebook: dyspnoea. Practitioner. 2003 Apr;247(1645):267, 270-3, 275-7. Review. PubMed PMID: 12705052. 1165: Svensson S, Lip GY. Patient perceptions of hypertension and its treatment. Blood Press. 2003;12(1):5-6. PubMed PMID: 12699128. 1166: Nadar S, Begum N, Kaur B, Sandhu S, Lip GY. Patients' understanding of anticoagulant therapy in a multiethnic population. J R Soc Med. 2003 Apr;96(4):175-9. PubMed PMID: 12668704; PubMed Central PMCID: PMC539445. 1167: Marín F, Roldán V, Climent V, Garcia A, Marco P, Lip GY. Is thrombogenesis in atrial fibrillation related to matrix metalloproteinase-1 and its inhibitor, 150 TIMP-1? Stroke. 2003 May;34(5):1181-6. Epub 2003 Mar 27. PubMed PMID: 12663879. 1168: Felmeden DC, Blann AD, Lip GY. Angiogenesis: basic pathophysiology and implications for disease. Eur Heart J. 2003 Apr;24(7):586-603. Review. PubMed PMID: 12657217. 1169: Makin AJ, Chung NA, Silverman SH, Lip GY. Vascular endothelial growth factor and tissue factor in patients with established peripheral artery disease: a link between angiogenesis and thrombogenesis? Clin Sci (Lond). 2003 Apr;104(4):397-404. PubMed PMID: 12653684. 1170: Chong AY, Blann AD, Lip GY. Assessment of endothelial damage and dysfunction: observations in relation to heart failure. QJM. 2003 Apr;96(4):253-67. Review. PubMed PMID: 12651970. 1171: Chin BS, Langford NJ, Nuttall SL, Gibbs CR, Blann AD, Lip GY. Anti-oxidative properties of beta-blockers and angiotensin-converting enzyme inhibitors in congestive heart failure. Eur J Heart Fail. 2003 Mar;5(2):171-4. PubMed PMID: 12644008. 1172: Lim HS, Lip GY. A case of breathlessness. Practitioner. 2003 Mar;247(1644):199-200, 204-7. Review. PubMed PMID: 12640828. 1173: Freestone B, Lip GY. Anticoagulation uptake in emergency department patients with atrial fibrillation. Stroke. 2003 Mar;34(3):591; author reply 591. Epub 2003 Feb 20. PubMed PMID: 12624274. 1174: Felmeden DC, Spencer CG, Blann AD, Beevers DG, Lip GY. Low-density lipoprotein subfractions and cardiovascular risk in hypertension: relationship to endothelial dysfunction and effects of treatment. Hypertension. 2003 Mar;41(3):528-33. Epub 2003 Feb 24. PubMed PMID: 12623954. 1175: Chong AY, Clarke CE, Dimitri WR, Lip GY. Brachial plexus injury as an unusual complication of coronary artery bypass graft surgery. Postgrad Med J. 2003 Feb;79(928):84-6. Review. PubMed PMID: 12612322; PubMed Central PMCID: PMC1742608. 151 1176: Sudlow C, Gubitz G, Sandercock P, Lip G. Stroke prevention. Clin Evid. 2002 Dec;(8):184-208. Review. Update in: Clin Evid. 2003 Dec;(10):246-72. PubMed PMID: 12603877. 1177: Felmeden DC, Spencer CG, Blann AD, Beevers DG, Lip GY. Physical activity in relation to indices of endothelial function and angiogenesis factors in hypertension: a substudy of the Anglo-Scandinavian Cardiac Outcomes Trial (ASCOT). J Intern Med. 2003 Jan;253(1):81-91. PubMed PMID: 12588540. 1178: Conway DS, Heeringa J, Van Der Kuip DA, Chin BS, Hofman A, Witteman JC, Lip GY. Atrial fibrillation and the prothrombotic state in the elderly: the Rotterdam Study. Stroke. 2003 Feb;34(2):413-7. PubMed PMID: 12574552. 1179: Lip GY. Hypertension, platelets, and the endothelium: the "thrombotic paradox" of hypertension (or "Birmingham paradox") revisited. Hypertension. 2003 Feb;41(2):199-200. PubMed PMID: 12574081. 1180: Lip GY, Beevers DG. Alcohol and cardiovascular disease--more than one paradox to consider. Alcohol and hypertension--does it matter? (no!). J Cardiovasc Risk. 2003 Feb;10(1):11-4. Review. PubMed PMID: 12569231. 1181: Caine GJ, Lip GY. D-dimer tests for assessment of patients with suspected pulmonary embolism. Arch Intern Med. 2003 Jan 27;163(2):243. PubMed PMID: 12546620. 1182: Lane D, Carroll D, Ring C, Beevers DG, Lip GY. In-hospital symptoms of depression do not predict mortality 3 years after myocardial infarction. Int J Epidemiol. 2002 Dec;31(6):1179-82. PubMed PMID: 12540719. 1183: Blann AD, Fitzmaurice DA, Lip GY. Anticoagulation in hospitals and general practice. BMJ. 2003 Jan 18;326(7381):153-6. Review. PubMed PMID: 12531851; PubMed Central PMCID: PMC1128888. 1184: Caine GJ, Blann AD, Stonelake PS, Kehoe ST, Lip GY. Tamoxifen for breast-cancer prevention. Lancet. 2003 Jan 11;361(9352):177-8; author reply 178. PubMed PMID: 12531605. 152 1185: Nadar S, Lim HS, Beevers DG, Lip GY. Lipid lowering in hypertension and heart protection: observations from the Anglo-Scandinavian Cardiac Outcomes Trial (ASCOT) and the Heart Protection Study. J Hum Hypertens. 2002 Dec;16(12):815-7. PubMed PMID: 12522461. 1186: Jilma B, Kamath S, Lip GY. ABC of antithrombotic therapy: Antithrombotic therapy in special circumstances. II-In children, thrombophilia, and miscellaneous conditions. BMJ. 2003 Jan 11;326(7380):93-6. Review. PubMed PMID: 12521976; PubMed Central PMCID: PMC1125035. 1187: Felmeden DC, Spencer CG, Belgore FM, Blann AD, Beevers DG, Lip GY. Endothelial damage and angiogenesis in hypertensive patients: relationship to cardiovascular risk factors and risk factor management. Am J Hypertens. 2003 Jan;16(1):11-20. PubMed PMID: 12517677. 1188: Jilma B, Kamath S, Lip GY. Antithrombotic therapy in special circumstances. I--pregnancy and cancer. BMJ. 2003 Jan 4;326(7379):37-40. Review. PubMed PMID: 12511462; PubMed Central PMCID: PMC1124928. 1189: Connolly DL, Lip GY, Chin BS. Antithrombotic strategies in acute coronary syndromes and percutaneous coronary interventions. BMJ. 2002 Dec 14;325(7377):1404-7. Review. PubMed PMID: 12480860; PubMed Central PMCID: PMC1124862. 1190: Meinertz T, Lip GY, Lombardi F, Sadowski ZP, Kalsch B, Camez A, Hewkin A, Eberle S; ERAFT Investigators. Efficacy and safety of propafenone sustained release in the prophylaxis of symptomatic paroxysmal atrial fibrillation (The European Rythmol/Rytmonorm Atrial Fibrillation Trial [ERAFT] Study). Am J Cardiol. 2002 Dec 15;90(12):1300-6. PubMed PMID: 12480038. 1191: Caine GJ, Lip GY. Dietary prevention of carcinogenesis in smokers. J Intern Med. 2002 Dec;252(6):577-8. PubMed PMID: 12472922. 1192: Makin AJ, Silverman SH, Lip GY. Ethnicity and peripheral vascular disease. Int J Clin Pract. 2002 Nov;56(9):645-8. PubMed PMID: 12469976. 1193: Watson RD, Chin BS, Lip GY. Antithrombotic therapy in acute coronary syndromes. BMJ. 2002 Dec 7;325(7376):1348-51. Review. PubMed PMID: 12468488; 153 PubMed Central PMCID: PMC1124806. 1194: Lip GY, Chin BS, Prasad N. ABC of antithrombotic therapy: Antithrombotic therapy in myocardial infarction and stable angina. BMJ. 2002 Nov 30;325(7375):1287-9. Review. PubMed PMID: 12458252; PubMed Central PMCID: PMC1124750. 1195: Chin BS, Chung NA, Gibbs CR, Blann AD, Lip GY. Vascular endothelial growth factor and soluble P-selectin in acute and chronic congestive heart failure. Am J Cardiol. 2002 Dec 1;90(11):1258-60. PubMed PMID: 12450612. 1196: Goldsmith I, Turpie AG, Lip GY. Valvar heart disease and prosthetic heart valves. BMJ. 2002 Nov 23;325(7374):1228-31. Review. PubMed PMID: 12446543; PubMed Central PMCID: PMC1124694. 1197: Caine GJ, Kehoe ST, Lip GY. The role of aspirin in carcinogenesis. Br J Cancer. 2002 Nov 18;87(11):1337-8. PubMed PMID: 12439726; PubMed Central PMCID: PMC2408895. 1198: Blann AD, Williams NR, Lip GY, Rajput-Williams J, Howard AN. Acute ingestion of red wine by men activates platelets but does not influence endothelial markers: no effect of white wine. Blood Coagul Fibrinolysis. 2002 Oct;13(7):647-51. PubMed PMID: 12439152. 1199: Kamath S, Chin BS, Blann AD, Lip GY. A study of platelet activation in paroxysmal, persistent and permanent atrial fibrillation. Blood Coagul Fibrinolysis. 2002 Oct;13(7):627-36. PubMed PMID: 12439149. 1200: Nadar S, Lip GY. Ongoing trials involving angiotensin-converting enzyme inhibitors. Expert Opin Investig Drugs. 2002 Nov;11(11):1633-43. Review. PubMed PMID: 12437509. 1201: Lip GY, Kamath S, Hart RG. ABC of antithrombotic therapy: Antithrombotic therapy for cerebrovascular disorders. BMJ. 2002 Nov 16;325(7373):1161-3. Review. PubMed PMID: 12433770; PubMed Central PMCID: PMC1124640. 1202: Makin A, Silverman S, Lip GY. Ethnic differences in peripheral vascular 154 disease. Int J Clin Pract. 2002 Oct;56(8):605-8. Review. PubMed PMID: 12425370. 1203: Makin AJ, Silverman SH, Lip GY. Antithrombotic therapy in peripheral vascular disease. BMJ. 2002 Nov 9;325(7372):1101-4. Review. PubMed PMID: 12424175; PubMed Central PMCID: PMC1124585. 1204: Nadar S, Lip GY. Secular trends in cardiovascular disease. J Hum Hypertens. 2002 Oct;16(10):663-6. PubMed PMID: 12420189. 1205: Kamath S, Blann AD, Chin BS, Lanza F, Aleil B, Cazenave JP, Lip GY. A study of platelet activation in atrial fibrillation and the effects of antithrombotic therapy. Eur Heart J. 2002 Nov;23(22):1788-95. PubMed PMID: 12419299. 1206: Kamath S, Lip GY. Atrial fibrillation in the elderly: anticoagulation strategies and indications in the very elderly. Am J Geriatr Cardiol. 2002 Nov-Dec;11(6):357-62; quiz 363-4. Review. PubMed PMID: 12417841. 1207: Blann AD, Lip GY, McCollum CN. Changes in von Willebrand factor and soluble ICAM, but not soluble VCAM, soluble E selectin or soluble thrombomodulin, reflect the natural history of the progression of atherosclerosis. Atherosclerosis. 2002 Dec;165(2):389-91. PubMed PMID: 12417293. 1208: Lip GY, Hart RG, Conway DS. Antithrombotic therapy for atrial fibrillation. BMJ. 2002 Nov 2;325(7371):1022-5. Review. PubMed PMID: 12411366; PubMed Central PMCID: PMC1124497. 1209: Caine GJ, Stonelake PS, Lip GY, Kehoe ST. The hypercoagulable state of malignancy: pathogenesis and current debate. Neoplasia. 2002 Nov-Dec;4(6):465-73. Review. PubMed PMID: 12407439; PubMed Central PMCID: PMC1550339. 1210: Turpie AG, Chin BS, Lip GY. ABC of antithrombotic therapy: Venous thromboembolism: treatment strategies. BMJ. 2002 Oct 26;325(7370):948-50. Review. Erratum in: BMJ. 2003 Jun 21;326(7403):1362. BMJ. 2003 Jan 18;326(7381):156. PubMed PMID: 12399348; PubMed Central PMCID: PMC1124446. 1211: Lee KW, Lip GY. Airborne occupational exposure and ABO phenotype: an example of gene-environment interaction in ischaemic heart disease? J Cardiovasc 155 Risk. 2002 Aug;9(4):179-82. PubMed PMID: 12394325. 1212: Lip PL, Felmeden DC, Blann AD, Matheou N, Thakur S, Cunliffe IA, Lip GY. Plasma vascular endothelial growth factor, soluble VEGF receptor FLT-1, and von Willebrand factor in glaucoma. Br J Ophthalmol. 2002 Nov;86(11):1299-302. PubMed PMID: 12386093; PubMed Central PMCID: PMC1771371. 1213: Turpie AG, Chin BS, Lip GY. Venous thromboembolism: pathophysiology, clinical features, and prevention. BMJ. 2002 Oct 19;325(7369):887-90. Review. PubMed PMID: 12386044; PubMed Central PMCID: PMC1124386. 1214: Tin LL, Beevers DG, Lip GY. Hypertension, left ventricular hypertrophy, and sudden death. Curr Cardiol Rep. 2002 Nov;4(6):449-57. Review. PubMed PMID: 12379162. 1215: Fitzmaurice DA, Blann AD, Lip GY. Bleeding risks of antithrombotic therapy. BMJ. 2002 Oct 12;325(7368):828-31. Review. PubMed PMID: 12376447; PubMed Central PMCID: PMC1124331. 1216: Caine GJ, Lip GY. Anticoagulants as anticancer agents? Lancet Oncol. 2002 Oct;3(10):591-2. PubMed PMID: 12372720. 1217: Conway DS, Pearce LA, Chin BS, Hart RG, Lip GY. Plasma von Willebrand factor and soluble p-selectin as indices of endothelial damage and platelet activation in 1321 patients with nonvalvular atrial fibrillation: relationship to stroke risk factors. Circulation. 2002 Oct 8;106(15):1962-7. PubMed PMID: 12370220. 1218: Blann AD, Landray MJ, Lip GY. ABC of antithrombotic therapy: An overview of antithrombotic therapy. BMJ. 2002 Oct 5;325(7367):762-5. Review. Erratum in: BMJ 2002 Nov 23;325(7374):1231. PubMed PMID: 12364307; PubMed Central PMCID: PMC1124276. 1219: Chung NA, Lydakis C, Belgore F, Blann AD, Lip GY. Angiogenesis in myocardial infarction. An acute or chronic process? Eur Heart J. 2002 Oct;23(20):1604-8. PubMed PMID: 12323160. 156 1220: Marco P, Marín F, García A, Roldán V, Lip GY. Do protein Z levels influence the prothrombotic state in atrial fibrillation? Thromb Res. 2002 May 15;106(4-5):269-70. PubMed PMID: 12297137. 1221: Sudlow C, Gubitz G, Sandercock P, Lip G. Stroke prevention. Clin Evid. 2002 Jun;(7):175-98. Review. Update in: Clin Evid. 2002 Dec;(8):184-208. PubMed PMID: 12230643. 1222: Freestone B, Kamath S, Lip G. Acute atrial fibrillation. Clin Evid. 2002 Jun;(7):1-10. Review. Update in: Clin Evid. 2003 Jun;(9):61-71. PubMed PMID: 12230635. 1223: Chung NA, Belgore F, Li-Saw-Hee FL, Conway DS, Blann AD, Lip GY. Is the hypercoagulable state in atrial fibrillation mediated by vascular endothelial growth factor? Stroke. 2002 Sep;33(9):2187-91. PubMed PMID: 12215585. 1224: Blann AD, Ridker PM, Lip GY. Inflammation, cell adhesion molecules, and stroke: tools in pathophysiology and epidemiology? Stroke. 2002 Sep;33(9):2141-3. PubMed PMID: 12215570. 1225: Nadar S, Beevers DG, Lip GY. Hypertension and renal failure. Clin Med. 2002 Jul-Aug;2(4):378-9. PubMed PMID: 12195870. 1226: Blann AD, Lip GY, McCollum CN. Influence of the risk factors for atherosclerosis on levels of soluble adhesion molecules and endothelial markers in peripheral vascular disease. Thromb Haemost. 2002 Aug;88(2):366-7. PubMed PMID: 12195717. 1227: Tayebjee M, Lip GY. Endothelin binding and calcium signalling in hypertension. J Hypertens. 2002 Sep;20(9):1711-2. PubMed PMID: 12195106. 1228: Blann AD, McCollum CN, Lip GY. Relationship between plasma markers of endothelial cell integrity and the Framingham cardiovascular disease risk-factor scores in apparently healthy individuals. Blood Coagul Fibrinolysis. 2002 Sep;13(6):513-8. PubMed PMID: 12192303. 1229: Felmeden DC, Beevers DG, Lip GY. Tackling malignant hypertension: not so 157 desperate now. Am Heart J. 2002 Aug;144(2):E4. PubMed PMID: 12177662. 1230: Lee KW, Freestone B, Harris L, Lip GY. HRT in a general practice population: further observations on the 'healthy cohort' effect. Int J Clin Pract. 2002 Jul-Aug;56(6):486-7. PubMed PMID: 12166552. 1231: Jilma B, Li-Saw-Hee FL, Wagner OF, Beevers DG, Lip GY. Effects of enalapril and losartan on circulating adhesion molecules and monocyte chemotactic protein-1. Clin Sci (Lond). 2002 Aug;103(2):131-6. PubMed PMID: 12149103. 1232: Kamath S, Blann AD, Chin BS, Lip GY. A prospective randomized trial of aspirin-clopidogrel combination therapy and dose-adjusted warfarin on indices of thrombogenesis and platelet activation in atrial fibrillation. J Am Coll Cardiol. 2002 Aug 7;40(3):484-90. PubMed PMID: 12142115. 1233: Gurney D, Lip GY, Blann AD. A reliable plasma marker of platelet activation: does it exist? Am J Hematol. 2002 Jun;70(2):139-44. Review. PubMed PMID: 12111787. 1234: Spencer CG, Gurney D, Blann AD, Beevers DG, Lip GY; ASCOT Steering Committee, Anglo-Scandinavian Cardiac Outcomes Trial. Von Willebrand factor, soluble P-selectin, and target organ damage in hypertension: a substudy of the Anglo-Scandinavian Cardiac Outcomes Trial (ASCOT). Hypertension. 2002 Jul;40(1):61-6. PubMed PMID: 12105139. 1235: Lip GY, Gibbs CR. Antiplatelet agents versus control or anticoagulation for heart failure in sinus rhythm: a Cochrane systematic review. QJM. 2002 Jul;95(7):461-8. Review. PubMed PMID: 12096151. 1236: Lip GY, Gibbs CR. Anticoagulation for heart failure in sinus rhythm: a Cochrane systematic review. QJM. 2002 Jul;95(7):451-9. Review. PubMed PMID: 12096150. 1237: Lip GY, Edmunds E, Nuttall SL, Landray MJ, Blann AD, Beevers DG. Oxidative stress in malignant and non-malignant phase hypertension. J Hum Hypertens. 2002 May;16(5):333-6. PubMed PMID: 12082494. 158 1238: Lip GY. Losartan and the meaning of LIFE. J Hum Hypertens. 2002 May;16(5):289-91. PubMed PMID: 12082487. 1239: Nadar S, Lip GY. Cardiomyopathy in practice. Practitioner. 2002 Jun;246(1635):416, 420-7. Review. PubMed PMID: 12073700. 1240: Lane DA, Lip GY, Millane TA. Quality of life in adults with congenital heart disease. Heart. 2002 Jul;88(1):71-5. PubMed PMID: 12067950; PubMed Central PMCID: PMC1767157. 1241: Lee KW, Felmeden DC, Lip GY. Lipid lowering and the assessment of endothelial function. Cardiovasc Res. 2002 Apr;54(1):191-2; author reply 193-4. PubMed PMID: 12062375. 1242: Freestone B, Lip GY. Antiarrhythmics in atrial fibrillation. Curr Opin Investig Drugs. 2002 Jan;3(1):84-8. Review. PubMed PMID: 12054078. 1243: Chin BS, Chong AY, Lip GY. A case of resistant hypertension in a 69-year-old man. J Hum Hypertens. 2002 Jun;16(6):445-7. PubMed PMID: 12037703. 1244: Lip GY, Blann AD, Farooqi IS, Zarifis J, Sagar G, Beevers DG. Sequential alterations in haemorheology, endothelial dysfunction, platelet activation and thrombogenesis in relation to prognosis following acute stroke: The West Birmingham Stroke Project. Blood Coagul Fibrinolysis. 2002 Jun;13(4):339-47. PubMed PMID: 12032400. 1245: Langman CM, Lyons AC, Lip GY. 'You cannot be serious!' compliance and antihypertensive regimens. Int J Clin Pract. 2002 Apr;56(3):164-6. Review. PubMed PMID: 12018816. 1246: Lip GY, Blann AD, Edmunds E, Beevers DG. Baseline abnormalities of endothelial function and thrombogenesis in relation to prognosis in essential hypertension. Blood Coagul Fibrinolysis. 2002 Jan;13(1):35-41. PubMed PMID: 11994565. 1247: Kamath S, Blann AD, Caine GJ, Gurney D, Chin BS, Lip GY. Platelet P-selectin levels in relation to plasma soluble P-selectin and 159 beta-thromboglobulin levels in atrial fibrillation. Stroke. 2002 May;33(5):1237-42. PubMed PMID: 11988597. 1248: Freestone B, Lip GY. Prevalence and risk factors of silent brain infarcts in the population. Stroke. 2002 May;33(5):1179-80; author reply 1179-80. PubMed PMID: 11988585. 1249: Lee KW, Felmeden DC, Lip GY. Statins and the assessment of endothelial function. J Intern Med. 2002 May;251(5):452-3; author reply 453-4. PubMed PMID: 11982746. 1250: Lane D, Beevers DG, Lip GY. Ethnic differences in blood pressure and the prevalence of hypertension in England. J Hum Hypertens. 2002 Apr;16(4):267-73. PubMed PMID: 11967721. 1251: Freestone B, Lip GY. Risk factors for mortality in acute myocardial infarction. Lancet. 2002 Apr 6;359(9313):1252. PubMed PMID: 11955574. 1252: Makin A, Silverman SH, Lip GY. Peripheral vascular disease and Virchow's triad for thrombogenesis. QJM. 2002 Apr;95(4):199-210. Review. PubMed PMID: 11937646. 1253: Caine GJ, Beevers DG, Lip GY. Cancer and ethnic minorities. Lancet Oncol. 2002 Jan;3(1):9. PubMed PMID: 11908508. 1254: Lip GY, Chin BS, Blann AD. Cancer and the prothrombotic state. Lancet Oncol. 2002 Jan;3(1):27-34. Review. PubMed PMID: 11908507. 1255: Tin LL, Beevers DG, Lip GY. Systolic vs diastolic blood pressure and the burden of hypertension. J Hum Hypertens. 2002 Mar;16(3):147-50. PubMed PMID: 11896501. 1256: Kamath S, Lip GY. YM-337. Yamanouchi. Curr Opin Investig Drugs. 2001 Aug;2(8):1093-6. PubMed PMID: 11892919. 1257: Felmeden DC, Lip GY. The renin-angiotensin-aldosterone system and 160 fibrinolysis. J Renin Angiotensin Aldosterone Syst. 2000 Sep;1(3):240-4. Review. PubMed PMID: 11881031. 1258: MacMahon KM, Lip GY. Psychological factors in heart failure: a review of the literature. Arch Intern Med. 2002 Mar 11;162(5):509-16. Review. PubMed PMID: 11871918. 1259: Landray MJ, Edmunds E, Li-Saw-Hee FL, Hughes BA, Beevers DG, Kendall MJ, Lip GY. Abnormal low-density lipoprotein subfraction profile in patients with untreated hypertension. QJM. 2002 Mar;95(3):165-71. PubMed PMID: 11865172. 1260: Blann AD, Lip GY. Soluble adhesion molecules and coronary heart disease. Lancet. 2002 Feb 9;359(9305):525-6; author reply 526-7. PubMed PMID: 11853825. 1261: Blann AD, Nitu-Whalley IC, Lee CA, Lip GY. Inverse relationship between plasma von Willebrand factor and soluble P selectin in patients with type 1 but not type 2 von Willebrand disease. Am J Hematol. 2002 Feb;69(2):135-7. PubMed PMID: 11835351. 1262: Blann AD, Belgore FM, McCollum CN, Silverman S, Lip PL, Lip GY. Vascular endothelial growth factor and its receptor, Flt-1, in the plasma of patients with coronary or peripheral atherosclerosis, or Type II diabetes. Clin Sci (Lond). 2002 Feb;102(2):187-94. PubMed PMID: 11834138. 1263: Lip GY, Kamath S, Jafri M, Mohammed A, Bareford D. Ethnic differences in patient perceptions of atrial fibrillation and anticoagulation therapy: the West Birmingham Atrial Fibrillation Project. Stroke. 2002 Jan;33(1):238-42. PubMed PMID: 11779916. 1264: Dhanjal TS, Lal M, Haynes R, Lip G. A comparison of cardiovascular risk factors among Indo-Asian and caucasian patients admitted with acute myocardial infarction in Kuala Lumpur, Malaysia and Birmingham, England. Int J Clin Pract. 2001 Dec;55(10):665-8. PubMed PMID: 11777289. 1265: Beevers DG, Lip GY. The protective effect of blocking angiotensin in both type I and type II diabetics with nephropathy. J Hum Hypertens. 2001 Dec;15(12):837-9. Review. PubMed PMID: 11773985. 161 1266: Lip GY, Beevers DG. ACE inhibitors in vascular disease: some PROGRESS, more HOPE. J Hum Hypertens. 2001 Dec;15(12):833-5. Review. PubMed PMID: 11773984. 1267: Chin BS, Lip GY. New pharmacological strategies for the treatment of heart failure. Curr Opin Investig Drugs. 2001 Jul;2(7):923-8. Review. PubMed PMID: 11757792. 1268: Lip GY, Hee FL. Paroxysmal atrial fibrillation. QJM. 2001 Dec;94(12):665-78. Review. PubMed PMID: 11744787. 1269: Lip GY, Conway DS. Increased von Willebrand factor in the endocardium as a local predisposing factor for thrombogenesis in overloaded human atrial appendage. J Am Coll Cardiol. 2001 Dec;38(7):2133-5. PubMed PMID: 11738328. 1270: Kamath S, Blann AD, Lip GY. Platelets and atrial fibrillation. Eur Heart J. 2001 Dec;22(24):2233-42. Review. PubMed PMID: 11728143. 1271: Gibbs CR, Blann AD, Edmunds E, Watson RD, Lip GY. Effects of acute exercise on hemorheological, endothelial, and platelet markers in patients with chronic heart failure in sinus rhythm. Clin Cardiol. 2001 Nov;24(11):724-9. PubMed PMID: 11714130. 1272: Williams E, Ansari M, Lip GY. Managing atrial fibrillation in the Accident and Emergency department. QJM. 2001 Nov;94(11):609-14. PubMed PMID: 11704690. 1273: Lane D, Lip GY. Blood pressure in different ethnic groups. Am J Cardiol. 2001 Nov 15;88(10):1218-9. PubMed PMID: 11703983. 1274: Felmeden DC, Lip GY, Beevers G. Calcium antagonists in diabetic hypertension. Diabetes Obes Metab. 2001 Oct;3(5):311-8. Review. PubMed PMID: 11703420. 1275: Chin BS, Futaba K, Jethwa A, Lip GY. The impact of coronary heart disease in determining use of hormone replacement therapy in a general practice population. Int J Clin Pract. 2001 Oct;55(8):515-8. PubMed PMID: 11695070. 162 1276: Farooqi IS, Keogh JM, Kamath S, Jones S, Gibson WT, Trussell R, Jebb SA, Lip GY, O'Rahilly S. Partial leptin deficiency and human adiposity. Nature. 2001 Nov 1;414(6859):34-5. PubMed PMID: 11689931. 1277: Langman CM, Lyons AC, Lip GY. Perceptions and behaviour of hypertensive patients: a divine intervention or a case for Hippocrates? J Hum Hypertens. 2001 Nov;15(11):751-4. PubMed PMID: 11687917. 1278: Lip GY, Gibbs CR. Anticoagulation for heart failure in sinus rhythm. Cochrane Database Syst Rev. 2001;(4):CD003336. Review. Update in: Cochrane Database Syst Rev. 2012;6:CD003336. PubMed PMID: 11687190. 1279: Lip GY, Gibbs CR. Antiplatelet agents versus control or anticoagulation for heart failure in sinus rhythm. Cochrane Database Syst Rev. 2001;(4):CD003333. Review. PubMed PMID: 11687189. 1280: Spencer CG, Beevers DG, Lip GY; Anglo-Scandinavian Cardiac Outcomes Trial. Haemorheological, endothelial and platelet function in subjects with hypertension: relationship to cardiovascular risk and influence of antihypertensive treatment. J Hum Hypertens. 2001 Aug;15 Suppl 1:S39-42. PubMed PMID: 11685908. 1281: Lip GY. Alcohol and the heart. Practitioner. 2001 Oct;245(1627):808-10, 812, 814 passim. Review. PubMed PMID: 11677896. 1282: Lip GY, Singh SP. Arrhythmias in adults following repair of tetralogy of Fallot. Am J Cardiol. 2001 Oct 15;88(8):936. PubMed PMID: 11676970. 1283: Felmeden DC, Lip GY. Antihypertensive therapy and cancer risk. Drug Saf. 2001;24(10):727-39. Review. PubMed PMID: 11676301. 1284: Goldsmith IR, Lip GY, Patel RL. A prospective study of changes in the quality of life of patients following mitral valve repair and replacement. Eur J Cardiothorac Surg. 2001 Nov;20(5):949-55. PubMed PMID: 11675179. 1285: Lane D, Carroll D, Ring C, Beevers DG, Lip GY. Predictors of attendance at 163 cardiac rehabilitation after myocardial infarction. J Psychosom Res. 2001 Sep;51(3):497-501. PubMed PMID: 11602219. 1286: Blann AD, Lanza F, Galajda P, Gurney D, Moog S, Cazenave JP, Lip GY. Increased platelet glycoprotein V levels in patients with coronary and peripheral atherosclerosis--the influence of aspirin and cigarette smoking. Thromb Haemost. 2001 Sep;86(3):777-83. PubMed PMID: 11583307. 1287: Lip GY. Regression of left ventricular hypertrophy and improved prognosis: some hope now . . . or hype? Circulation. 2001 Oct 2;104(14):1582-4. PubMed PMID: 11581130. 1288: Conway DS, Lip GY. New antiarrhythmic agents for atrial fibrillation. Curr Opin Investig Drugs. 2001 Jan;2(1):87-92. Review. PubMed PMID: 11527018. 1289: Makin AJ, Conway DS, Lip GY. Systemic thromboembolism in atrial fibrillation. Arch Intern Med. 2001 Aug 13-27;161(15):1920-4. PubMed PMID: 11493151. 1290: Spencer CG, Lip GY. Left internal mammary graft stenosis and restenosis following angioplasty and stenting. Heart. 2001 Sep;86(3):E9. PubMed PMID: 11514500; PubMed Central PMCID: PMC1729912. 1291: Li-Saw-Hee FL, Blann AD, Gurney D, Lip GY. Plasma von Willebrand factor, fibrinogen and soluble P-selectin levels in paroxysmal, persistent and permanent atrial fibrillation. Effects of cardioversion and return of left atrial function. Eur Heart J. 2001 Sep;22(18):1741-7. PubMed PMID: 11511124. 1292: Lydakis C, Beevers M, Beevers DG, Lip GY. The prevalence of pre-eclampsia and obstetric outcome in pregnancies of normotensive and hypertensive women attending a hospital specialist clinic. Int J Clin Pract. 2001 Jul-Aug;55(6):361-7. PubMed PMID: 11501223. 1293: Lip GY, Edmunds E, Hee FL, Blann AD, Beevers DG. A cross-sectional, diurnal, and follow-up study of platelet activation and endothelial dysfunction in malignant phase hypertension. Am J Hypertens. 2001 Aug;14(8 Pt 1):823-8. PubMed PMID: 11497201. 164 1294: Mant J, Fitzmaurice D, Murray E, Lip GY, Hobbs FD. Long term anticoagulation or antiplatelet treatment. Inclusion criteria determine results of review. BMJ. 2001 Jul 28;323(7306):233-4; author reply 235-6. PubMed PMID: 11496884. 1295: Kamath S, Blann AD, Lip GY. Platelet activation: assessment and quantification. Eur Heart J. 2001 Sep;22(17):1561-71. Review. PubMed PMID: 11492985. 1296: Chin BS, Kharim S, Ghaffar A, Rehman A, Lip GY. Secondary prevention of cardiovascular disease and diabetes: still suboptimal in patients with myocardial infarction. J Intern Med. 2001 Aug;250(2):180-2. PubMed PMID: 11489070. 1297: Conway D, Lip GY. Atrial fibrillation and stroke: more concepts and controversies. Stroke. 2001 Aug;32(8):1931-8. PubMed PMID: 11486128. 1298: Makin A, Chin BS, Lip GY. Altered cardiac function. J R Coll Surg Edinb. 2001 Jun;46(3):190-1. PubMed PMID: 11478028. 1299: Lip PL, Lip GY. Further pathophysiological insights into age related macular degeneration. Br J Ophthalmol. 2001 Aug;85(8):1013. PubMed PMID: 11466264; PubMed Central PMCID: PMC1724076. 1300: Lip GY, Edmunds E, Martin SC, Jones AF, Blann AD, Beevers DG. A pilot study of homocyst(e)ine levels in essential hypertension: relationship to von Willebrand factor, an index of endothelial damage. Am J Hypertens. 2001 Jul;14(7 Pt 1):627-31. PubMed PMID: 11465645. 1301: Conway DS, Lip GY. Anticoagulation and atrial fibrillation. Postgrad Med J. 2001 Jul;77(909):487; author reply 488. PubMed PMID: 11464813; PubMed Central PMCID: PMC1760994. 1302: Makin A, Lip GY, Silverman S, Beevers DG. Peripheral vascular disease and hypertension: a forgotten association? J Hum Hypertens. 2001 Jul;15(7):447-54. Review. PubMed PMID: 11464253. 165 1303: Chung NA, Lip GY. Right atrial function in hypertension. J Hum Hypertens. 2001 Jul;15(7):439-41. PubMed PMID: 11464251. 1304: Lip GY, Blann AD, Farooqi IS, Zarifis J, Sagar G, Beevers DG. Abnormal haemorheology, endothelial function and thrombogenesis in relation to hypertension in acute (ictus < 12 h) stroke patients: the West Birmingham Stroke Project. Blood Coagul Fibrinolysis. 2001 Jun;12(4):307-15. PubMed PMID: 11460015. 1305: Chin B, Spencer CG, Lip GY. Unstable angina following acute MI in a patient with bilateral coronary artery fistulae: an unusual presentation of coronary steal? Int J Clin Pract. 2001 Jun;55(5):342-3. PubMed PMID: 11452687. 1306: Lip GY, Beevers M, Beevers DG, Dillon MJ. The measurement of blood pressure and the detection of hypertension in children and adolescents. J Hum Hypertens. 2001 Jun;15(6):419-23. PubMed PMID: 11439318. 1307: Lane DA, Lip GY. Ethnic differences in hypertension and blood pressure control in the UK. QJM. 2001 Jul;94(7):391-6. Review. PubMed PMID: 11435635. 1308: Lip GY, Kamath S. Thromboprophylaxis for atrial flutter. Eur Heart J. 2001 Jun;22(12):984-7. PubMed PMID: 11428832. 1309: Belgore FM, Lip GY, Bareford D, Wadley M, Stonelake P, Blann AD. Plasma levels of vascular endothelial growth factor (VEGF) and its receptor, Flt-1, in haematological cancers: a comparison with breast cancer. Am J Hematol. 2001 Jan;66(1):59-61. PubMed PMID: 11426496. 1310: Blann AD, Gurney D, Hughes E, Buggins P, Silverman SH, Lip GY. Influence of pravastatin on lipoproteins, and on endothelial, platelet, and inflammatory markers in subjects with peripheral artery disease. Am J Cardiol. 2001 Jul 1;88(1):A7-8, 89-92. PubMed PMID: 11423069. 1311: Conway DS, Lip GY. Helicobacter pylori as the cause of coronary artery restenosis following angioplasty--is the way to a man's heart disease through his stomach? Dig Liver Dis. 2001 Apr;33(3):214-6. Review. PubMed PMID: 11407664. 1312: Lip GY, Blann AD. Atrial fibrillation and abnormalities of hemostatic 166 factors. Am J Cardiol. 2001 May 1;87(9):1136-7. PubMed PMID: 11396424. 1313: Edmunds E, Landray MJ, Li-Saw-Hee FL, Hughes BA, Beevers DG, Lip GY. Dyslipidaemia in patients with malignant-phase hypertension. QJM. 2001 Jun;94(6):327-32. PubMed PMID: 11391031. 1314: Lip GY, Tan EK, Lau CK, Kamath S. Diurnal variation in stroke onset in atrial fibrillation. Stroke. 2001 Jun;32(6):1443-8. PubMed PMID: 11387515. 1315: Chung NA, Lip GY, Beevers M, Beevers DG. Angiotensin-II-receptor inhibitors in pregnancy. Lancet. 2001 May 19;357(9268):1620-1. PubMed PMID: 11386316. 1316: Goldsmith IR, Lip GY, Patel RL. A prospective study of changes in patients' quality of life after aortic valve replacement. J Heart Valve Dis. 2001 May;10(3):346-53. PubMed PMID: 11380097. 1317: Li-Saw-Hee FL, Beevers DG, Lip GY. Effect of antihypertensive therapy using enalapril or losartan on haemostatic markers in essential hypertension: a pilot prospective randomised double-blind parallel group trial. Int J Cardiol. 2001 May;78(3):241-6. PubMed PMID: 11376827. 1318: Conway D, Lip GY. Case book: palpitations. Practitioner. 2001 May;245(1622):393-6, 398, 401. Review. PubMed PMID: 11373969. 1319: Blann AD, Belgore FM, Constans J, Conri C, Lip GY. Plasma vascular endothelial growth factor and its receptor Flt-1 in patients with hyperlipidemia and atherosclerosis and the effects of fluvastatin or fenofibrate. Am J Cardiol. 2001 May 15;87(10):1160-3. PubMed PMID: 11356390. 1320: Felmeden DC, Lip GY. Resistant hypertension and the Birmingham Hypertension Square. Curr Hypertens Rep. 2001 Jun;3(3):203-8. Review. PubMed PMID: 11353570. 1321: O'Brien E, Beevers G, Lip GY. ABC of hypertension: Blood pressure measurement. Part IV-automated sphygmomanometry: self blood pressure measurement. BMJ. 2001 May 12;322(7295):1167-70. Review. PubMed PMID: 11348915; PubMed Central PMCID: PMC1120288. 167 1322: Li-Saw-Hee FL, Blann AD, Edmunds E, Gibbs CR, Lip GY. Effect of acute exercise on the raised plasma fibrinogen, soluble P-selectin and von Willebrand factor levels in chronic atrial fibrillation. Clin Cardiol. 2001 May;24(5):409-14. PubMed PMID: 11346250. 1323: Kamath S, Lip GY. Targeting patients with atrial fibrillation and improving their anticoagulation management. Clin Cardiol. 2001 May;24(5):355-7. PubMed PMID: 11346241. 1324: O'Brien E, Beevers G, Lip GY. ABC of hypertension. Blood pressure measurement. Part III-automated sphygmomanometry: ambulatory blood pressure measurement. BMJ. 2001 May 5;322(7294):1110-4. Review. PubMed PMID: 11337446; PubMed Central PMCID: PMC1120240. 1325: Wong PS, Lip GY, Gearty JC, Arkell DG, Howie AJ, Ferreira MA, Beevers DG. Renal cell carcinoma and malignant phase hypertension. Blood Press. 2001;10(1):16-21. PubMed PMID: 11332328. 1326: Beevers G, Lip GY, O'Brien E. ABC of hypertension: Blood pressure measurement. Part II-conventional sphygmomanometry: technique of auscultatory blood pressure measurement. BMJ. 2001 Apr 28;322(7293):1043-7. Review. PubMed PMID: 11325773; PubMed Central PMCID: PMC1120188. 1327: Kamath S, Lip G. Digoxin: a drug whose time has gone? Int J Clin Pract. 2001 Mar;55(2):77-8. PubMed PMID: 11321863. 1328: Blann AD, Lip GY. Virchow's triad revisited: the importance of soluble coagulation factors, the endothelium, and platelets. Thromb Res. 2001 Feb 15;101(4):321-7. Review. PubMed PMID: 11320984. 1329: Conway D, Lip GY. The ECG and left ventricular hypertrophy in primary care hypertensives. J Hum Hypertens. 2001 Apr;15(4):215-7. PubMed PMID: 11319668. 1330: Chin BS, Lip GY. Blockade of the renin-angiotensin-aldosterone system with combination angiotensin receptor antagonist and ACE inhibitor therapy: observations from Val-HeFT and CALM. J Hum Hypertens. 2001 Feb;15(2):89-92. PubMed PMID: 11317186. 168 1331: Lip GY, Beevers DG. Calcium channel blockers in hypertension: the debate reawakens. J Hum Hypertens. 2001 Feb;15(2):85-7. PubMed PMID: 11317185. 1332: Beevers G, Lip GY, O'Brien E. ABC of hypertension. Blood pressure measurement. Part I-sphygmomanometry: factors common to all techniques. BMJ. 2001 Apr 21;322(7292):981-5. Review. PubMed PMID: 11312235; PubMed Central PMCID: PMC1120141. 1333: Beevers G, Lip GY, O'Brien E. ABC of hypertension: The pathophysiology of hypertension. BMJ. 2001 Apr 14;322(7291):912-6. Review. PubMed PMID: 11302910; PubMed Central PMCID: PMC1120075. 1334: Lip PL, Blann AD, Hope-Ross M, Gibson JM, Lip GY. Age-related macular degeneration is associated with increased vascular endothelial growth factor, hemorheology and endothelial dysfunction. Ophthalmology. 2001 Apr;108(4):705-10. PubMed PMID: 11297487. 1335: Belgore FM, Blann AD, Lip GY. Measurement of free and complexed soluble vascular endothelial growth factor receptor, Flt-1, in fluid samples: development and application of two new immunoassays. Clin Sci (Lond). 2001 May;100(5):567-75. PubMed PMID: 11294698. 1336: Li-Saw-Hee FL, Lip GY. Effects of balloon mitral valvuloplasty on systemic and regional left atrial levels of prothrombin fragment 1+2 in mitral stenosis. Clin Sci (Lond). 2001 May;100(5):467-8. PubMed PMID: 11294684. 1337: Lane D, Carroll D, Ring C, Beevers DG, Lip GY. Mortality and quality of life 12 months after myocardial infarction: effects of depression and anxiety. Psychosom Med. 2001 Mar-Apr;63(2):221-30. PubMed PMID: 11292269. 1338: Lip GY, Edmunds E, Beevers DG. Should patients with hypertension receive antithrombotic therapy? J Intern Med. 2001 Mar;249(3):205-14. Review. PubMed PMID: 11285041. 1339: Lip GY, Felmeden DC. Hormone replacement therapy and cardiovascular risk: do abnormalities of coagulation and fibrinolysis matter? J Intern Med. 2001 169 Mar;249(3):201-4. PubMed PMID: 11285040. 1340: Gibbs CR, Blann AD, Watson RD, Lip GY. Abnormalities of hemorheological, endothelial, and platelet function in patients with chronic heart failure in sinus rhythm: effects of angiotensin-converting enzyme inhibitor and beta-blocker therapy. Circulation. 2001 Apr 3;103(13):1746-51. PubMed PMID: 11282905. 1341: Gurney D, Poole C, Kehoe S, Lip GY, Blann AD. Soluble P-selectin is influenced by cancer chemotherapy. Platelets. 2001 Feb;12(1):37-8. PubMed PMID: 11281629. 1342: Belgore FM, Blann AD, Li-Saw-Hee FL, Beevers DG, Lip GY. Plasma levels of vascular endothelial growth factor and its soluble receptor (SFlt-1) in essential hypertension. Am J Cardiol. 2001 Mar 15;87(6):805-7, A9. PubMed PMID: 11249912. 1343: Chin B, Lip GY. Cariporide Aventis. Curr Opin Investig Drugs. 2000 Nov;1(3):340-6. Review. PubMed PMID: 11249717. 1344: Kamath S, Lip GY. Cardioversion of atrial fibrillation or flutter: a 'stunning' problem. Eur Heart J. 2001 Mar;22(6):520-1. PubMed PMID: 11237547. 1345: Blann AD, Gurney D, Wadley M, Bareford D, Stonelake P, Lip GY. Increased soluble P-selectin in patients with haematological and breast cancer: a comparison with fibrinogen, plasminogen activator inhibitor and von Willebrand factor. Blood Coagul Fibrinolysis. 2001 Jan;12(1):43-50. PubMed PMID: 11229826. 1346: Lip GY, Kamath S. Do electrophysiological interventions confer a prothrombotic state? Pacing Clin Electrophysiol. 2001 Jan;24(1):1-4. PubMed PMID: 11227953. 1347: Felmeden DC, Lip GY, Beevers M, Beevers DG. The placebo effect and white coat effect in isolated systolic hypertension and systo-diastolic hypertension. Blood Press. 2000;9(6):335-9. PubMed PMID: 11212062. 1348: Felmeden DC, Lip GY. Myocardial bridging. Int J Clin Pract. 2000 Oct;54(8):542-3. PubMed PMID: 11198735. 170 1349: Felmeden DC, Lip GY. Hormone replacement therapy and hypertension. Blood Press. 2000;9(5):246-9. Review. PubMed PMID: 11193126. 1350: Lip GY, Zarifis J. Atrial fibrillation and stroke in patients admitted to a city centre hospital serving a multiethnic community. Int J Cardiol. 2000 Sep 15;75(2-3):311-2. PubMed PMID: 11186970. 1351: Lip GY, Zarifis J, Beevers DG. Blood pressure monitoring in atrial fibrillation using electronic devices. Arch Intern Med. 2001 Jan 22;161(2):294. PubMed PMID: 11176748. 1352: Lip GY. Lipoprotein (a) and thrombogenesis in left ventricular dysfunction. Eur Heart J. 2001 Jan;22(2):181-2. PubMed PMID: 11161921. 1353: Li-Saw-Hee FL, Blann AD, Lip GY. Effects of fixed low-dose warfarin, aspirin-warfarin combination therapy, and dose-adjusted warfarin on thrombogenesis in chronic atrial fibrillation. Stroke. 2000 Apr;31(4):828-33. PubMed PMID: 10753983. 1354: Goldsmith IR, Blann AD, Patel RL, Lip GY. Effect of aortic valve replacement on plasma soluble P-selectin, von Willebrand factor, and fibrinogen. Am J Cardiol. 2001 Jan 1;87(1):107-10, A9. PubMed PMID: 11137845. 1355: Kamath S, Yunus F, Ganesalingam R, Lip GY. Diurnal variation and cardiovascular disease. Am Heart J. 2001 Jan;141(1):E3. PubMed PMID: 11136506. 1356: Lip GY, Blann AD. Thrombogenesis and fibrinolysis in acute coronary syndromes. Important facets of a prothrombotic or hypercoagulable state? J Am Coll Cardiol. 2000 Dec;36(7):2044-6. PubMed PMID: 11127438. 1357: Lane D, Carroll D, Ring C, Beevers DG, Lip GY. Effects of depression and anxiety on mortality and quality-of-life 4 months after myocardial infarction. J Psychosom Res. 2000 Oct;49(4):229-38. PubMed PMID: 11119779. 1358: Lip GY. Hypertension and the prothrombotic state. J Hum Hypertens. 2000 Oct-Nov;14(10-11):687-90. Review. PubMed PMID: 11095159. 171 1359: Felmeden D, Singh SP, Lip GY. Anomalous coronary arteries of aortic origin. Int J Clin Pract. 2000 Jul-Aug;54(6):390-4. Review. PubMed PMID: 11092113. 1360: Lip GY, Blann AD, Beevers DG. Helicobacter pylori seropositivity, lipid concentrations and haemostatic factors. J Intern Med. 2000 Oct;248(4):354-6. PubMed PMID: 11086649. 1361: Lip GY, Lydakis C, Nuttall SL, Landray MJ, Watson RD, Blann AD. A pilot study of streptokinase-induced endothelial injury and platelet activation following acute myocardial infarction. J Intern Med. 2000 Oct;248(4):316-8. PubMed PMID: 11086642. 1362: Gibbs CR, Watson RD, Singh SP, Lip GY. Management of pericardial effusion by drainage: a survey of 10 years' experience in a city centre general hospital serving a multiracial population. Postgrad Med J. 2000 Dec;76(902):809-13. PubMed PMID: 11085787; PubMed Central PMCID: PMC1741828. 1363: Lane D, Carroll D, Ring C, Beevers DG, Lip GY. Do depression and anxiety predict recurrent coronary events 12 months after myocardial infarction? QJM. 2000 Nov;93(11):739-44. PubMed PMID: 11077030. 1364: Steiner MK, Clarkson PB, Lip GY. Myocardial infarction complicating hormone replacement therapy in a young woman with normal coronary arteries. Int J Clin Pract. 2000 Sep;54(7):475-7. PubMed PMID: 11070576. 1365: Goldsmith I, Kumar P, Carter P, Blann AD, Patel RL, Lip GY. Atrial endocardial changes in mitral valve disease: a scanning electron microscopy study. Am Heart J. 2000 Nov;140(5):777-84. PubMed PMID: 11054625. 1366: Li-Saw-Hee FL, Edmunds E, Blann AD, Beevers DG, Lip GY. Matrix metalloproteinase-9 and tissue inhibitor metalloproteinase-1 levels in essential hypertension. Relationship to left ventricular mass and anti-hypertensive therapy. Int J Cardiol. 2000 Aug;75(1):43-7. PubMed PMID: 11054505. 1367: Blann AD, Lip GY. Left atrial thrombin generation and prothrombin fragment 1+2. Clin Sci (Lond). 2000 Nov;99(5):411-2. PubMed PMID: 11052921. 172 1368: Belgore FM, Lip GY, Blann AD. Vascular endothelial growth factor and its receptor, Flt-1, in smokers and non-smokers. Br J Biomed Sci. 2000;57(3):207-13. PubMed PMID: 11050771. 1369: Lip GY, Felmeden DC, Li-Saw-Hee FL, Beevers DG. Hypertensive heart disease. A complex syndrome or a hypertensive 'cardiomyopathy'? Eur Heart J. 2000 Oct;21(20):1653-65. Review. PubMed PMID: 11032692. 1370: Belgore FM, Blann AD, Lip GY. sFlt-1, a potential antagonist for exogenous VEGF. Circulation. 2000 Oct 10;102(15):E108-9. PubMed PMID: 11023949. 1371: Jolly K, rouse A, Lip GY. National service framework for coronary heart disease. Many operators and facilities will not meet standards set out in framework. BMJ. 2000 Sep 9;321(7261):634-5. PubMed PMID: 11023320. 1372: Belgore FM, Lip GY, Bareford D, Blann AD. Plasma levels of vascular endothelial growth factor (VEGF) in haematological cancers. Br J Haematol. 2000 Aug;110(2):496-7. PubMed PMID: 11023294. 1373: Li-Saw-Hee FL, Blann AD, Lip GY. Effect of degree of blood pressure on the hypercoagulable state in chronic atrial fibrillation. Am J Cardiol. 2000 Oct 1;86(7):795-7, A9. PubMed PMID: 11018206. 1374: Blann AD, Amiral J, McCollum CN, Lip GY. Differences in free and total tissue factor pathway inhibitor, and tissue factor in peripheral artery disease compared to healthy controls. Atherosclerosis. 2000 Sep;152(1):29-34. PubMed PMID: 10996336. 1375: Chin B, Reid M, Alderslade G, Lip GY. Malnutrition in hospital. QJM. 2000 Sep;93(9):640-1. PubMed PMID: 10984561. 1376: Edmunds E, Landray M, Lip GY. Hormone replacement therapy and intima-media thickness of the common carotid artery: the Rotterdam study. Stroke. 2000 Sep;31(9):2273-4. PubMed PMID: 10978138. 173 1377: Edmunds E, Lip GY. An independent verdict: does infection with Helicobacter pylori cause ischaemic heart disease? Dig Liver Dis. 2000 Jan-Feb;32(1):69-70. Review. PubMed PMID: 10975759. 1378: Lip GY. The prothrombotic state in atrial fibrillation: new insights, more questions, and clear answers needed. Am Heart J. 2000 Sep;140(3):348-50. PubMed PMID: 10966527. 1379: Kamath S, Lip GY. Managing cardiac arrhythmias. Part II. Management strategies for specific cardiac arrhythmias. Practitioner. 2000 Jun;244(1611):568-73. Review. PubMed PMID: 10962849. 1380: Kamath S, Lip GY. Managing cardiac arrhythmias. Part I. General principles of investigation and management. Practitioner. 2000 Jun;244(1611):559, 560, 563-5. Review. PubMed PMID: 10962848. 1381: Lip GY, Beevers M, Beevers DG. Do patients with de novo hypertension differ from patients with previously known hypertension when malignant phase hypertension occurs? Am J Hypertens. 2000 Aug;13(8):934-9. PubMed PMID: 10950403. 1382: Belgore FM, Lip GY, Blann AD. Successful therapy reduces levels of vascular endothelial growth factor (VEGF) in patients with hypertension and patients with hypercholesterolemia. Atherosclerosis. 2000 Aug;151(2):599. PubMed PMID: 10944083. 1383: Goldsmith IR, Foo LS, Blann AD, Lip GY. Increased platelet activation and endothelial dysfunction in patients with atrial fibrillation immediately following percutaneous balloon mitral valvuloplasty. Clin Cardiol. 2000 Aug;23(8):587-90. PubMed PMID: 10941544. 1384: Edmunds E, Landray M, Lip GY. Association between elevated plasma fibrinogen and the small, dense low-density lipoprotein phenotype among postmenopausal women. Am J Cardiol. 2000 Jul 1;86(1):126. PubMed PMID: 10928941. 1385: Lip GY, Lydakis C, Beevers DG. Management of patients with myocardial infarction and hypertension. Eur Heart J. 2000 Jul;21(14):1125-34. Review. PubMed PMID: 10924295. 174 1386: Goldsmith IR, Blann AD, Patel RL, Lip GY. Reduced indexes of left atrial hypercoagulability in patients with severe mitral regurgitation. Am J Cardiol. 2000 Jul 15;86(2):234-6. PubMed PMID: 10913493. 1387: Lip GY, Kamath S, Blann AD. Haematocrit and plasma viscosity in atrial fibrillation. Int J Cardiol. 2000 Jun 12;74(1):85-8. PubMed PMID: 10912439. 1388: Lip PL, Belgore F, Blann AD, Hope-Ross MW, Gibson JM, Lip GY. Plasma VEGF and soluble VEGF receptor FLT-1 in proliferative retinopathy: relationship to endothelial dysfunction and laser treatment. Invest Ophthalmol Vis Sci. 2000 Jul;41(8):2115-9. PubMed PMID: 10892852. 1389: Chin B, Lip GY. Antithrombotic therapy in atrial fibrillation. J R Soc Med. 2000 May;93(5):278-9. PubMed PMID: 10884790; PubMed Central PMCID: PMC1298023. 1390: Blann AD, Lip GY. Cell adhesion molecules in cardiovascular disease and its risk factors--what can soluble levels tell us? J Clin Endocrinol Metab. 2000 May;85(5):1745-7. Review. PubMed PMID: 10843144. 1391: Li-Saw-Hee FL, Blann AD, Lip GY. A cross-sectional and diurnal study of thrombogenesis among patients with chronic atrial fibrillation. J Am Coll Cardiol. 2000 Jun;35(7):1926-31. PubMed PMID: 10841245. 1392: Spencer CG, Lip GY. Haemorheological factors in hypertension. J Hum Hypertens. 2000 May;14(5):291-3. Review. PubMed PMID: 10822313. 1393: Beevers DG, Lip GY. Do alpha blockers cause heart failure and stroke? Observations from ALLHAT. J Hum Hypertens. 2000 May;14(5):287-9. Review. PubMed PMID: 10822312. 1394: Goldsmith IR, Blann AD, Patel RL, Lip GY. von Willebrand factor, fibrinogen, and soluble P-selectin levels after mitral valve replacement versus mitral valve repair. Am J Cardiol. 2000 May 15;85(10):1218-22. PubMed PMID: 10802004. 1395: Gibbs CR, Lip GY, Beevers DG. Salt and cardiovascular disease: clinical and 175 epidemiological evidence. J Cardiovasc Risk. 2000 Feb;7(1):9-13. Review. PubMed PMID: 10785868. 1396: Goldsmith IR, Blann AD, Patel RL, Lip GY. Plasma fibrinogen, soluble P-selectin, and von Willebrand factor in aortic valve disease: evidence for abnormal haemorheology, platelet activation, and endothelial dysfunction. Heart. 2000 May;83(5):577-8. PubMed PMID: 10768913; PubMed Central PMCID: PMC1760819. 1397: Gibbs CR, Lip GY. Takayasu's pulseless disease. Clin Cardiol. 2000 Apr;23(4):293-4. PubMed PMID: 10763080. 1398: Edmunds E, Lip GY. Cardiovascular risk in women: the cardiologist's perspective. QJM. 2000 Mar;93(3):135-45. Review. PubMed PMID: 10751232. 1399: Palfrey D, Cook PJ, Smythe JA, Lip GY, Hine AV. Simplified preparation of human arterial sections for PCR analysis of Chlamydia pneumoniae and human DNA. Mol Pathol. 1999 Oct;52(5):289-94. PubMed PMID: 10748879; PubMed Central PMCID: PMC395712. 1400: Kamath S, Lip GY. Mitral regurgitation and atrial fibrillation: milder the disease, higher the risk? Int J Cardiol. 2000 Feb 15;72(3):235-7. PubMed PMID: 10716132. 1401: Lip GY. Atrial fibrillation in general practice. Practitioner. 1999 Oct;243(1603):746-51. Review. PubMed PMID: 10715873. 1402: Hobbs FD, Davis RC, Lip GY. ABC of heart failure: Heart failure in general practice. BMJ. 2000 Mar 4;320(7235):626-9. Review. PubMed PMID: 10698886; PubMed Central PMCID: PMC1117656. 1403: Gibbs CR, Davies MK, Lip GY. ABC of heart failure. Management: digoxin and other inotropes, beta blockers, and antiarrhythmic and antithrombotic treatment. BMJ. 2000 Feb 19;320(7233):495-8. Review. PubMed PMID: 10678868; PubMed Central PMCID: PMC1127534. 1404: Lip GY, Beevers M, Beevers DG. Serum urate is associated with baseline renal dysfunction but not survival or deterioration in renal function in 176 malignant phase hypertension. J Hypertens. 2000 Jan;18(1):97-101. PubMed PMID: 10678549. 1405: Edmunds E, Beevers DG, Lip GY. What has happened to malignant hypertension? A disease no longer vanishing. J Hum Hypertens. 2000 Mar;14(3):159-61. Review. PubMed PMID: 10694828. 1406: Lip GY, Li-Saw-Hee FL. Anticoagulation of older patients. Age Ageing. 2000 Jan;29(1):3-4. PubMed PMID: 10690686. 1407: Lip GY. Lipoprotein(a) in atrial fibrillation. Am Heart J. 2000 Mar;139(3):555-6. PubMed PMID: 10689273. 1408: Millane T, Jackson G, Gibbs CR, Lip GY. ABC of heart failure. Acute and chronic management strategies. BMJ. 2000 Feb 26;320(7234):559-62. Review. PubMed PMID: 10688565; PubMed Central PMCID: PMC1117602. 1409: Davies MK, Gibbs CR, Lip GY. ABC of heart failure. Management: diuretics, ACE inhibitors, and nitrates. BMJ. 2000 Feb 12;320(7232):428-31. Review. PubMed PMID: 10669450; PubMed Central PMCID: PMC1117548. 1410: Gibbs CR, Jackson G, Lip GY. ABC of heart failure. Non-drug management. BMJ. 2000 Feb 5;320(7231):366-9. Review. PubMed PMID: 10657338; PubMed Central PMCID: PMC1127148. 1411: Davies MK, Gibbs CR, Lip GY. ABC of heart failure. BMJ. 2000 Jan 29;320(7230):297-300. Review. PubMed PMID: 10650030; PubMed Central PMCID: PMC1117489. 1412: Lip GY, Rathore VS, Katira R, Watson RD, Singh SP. Do Indo-Asians have smaller coronary arteries? Postgrad Med J. 1999 Aug;75(886):463-6. PubMed PMID: 10646023; PubMed Central PMCID: PMC1741307. 1413: Lip GY, Blann AD. Does hypertension confer a prothrombotic state? Virchow's triad revisited. Circulation. 2000 Jan 25;101(3):218-20. PubMed PMID: 10645912. 177 1414: Lip GY, Gibbs CR, Beevers DG. ABC of heart failure: aetiology. BMJ. 2000 Jan 8;320(7227):104-7. Review. PubMed PMID: 10625270; PubMed Central PMCID: PMC1117365. 1415: Watson RD, Gibbs CR, Lip GY. ABC of heart failure. Clinical features and complications. BMJ. 2000 Jan 22;320(7229):236-9. Review. PubMed PMID: 10642237; PubMed Central PMCID: PMC1117436. 1416: Jackson G, Gibbs CR, Davies MK, Lip GY. ABC of heart failure. Pathophysiology. BMJ. 2000 Jan 15;320(7228):167-70. Review. PubMed PMID: 10634740; PubMed Central PMCID: PMC1128747. 1417: Lip GY. Target organ damage and the prothrombotic state in hypertension. Hypertension. 2000 Dec;36(6):975-7. PubMed PMID: 11116110. 1418: Lane D, Carroll D, Lip GY. Psychology in coronary care. QJM. 1999 Aug;92(8):425-31. Review. PubMed PMID: 10627858. 1419: Lip PL, Lip GY. Reversible anterior ischaemic optic neuropathy in accelerated hypertension. Eye (Lond). 1999 Jun;13 ( Pt 3a):391. PubMed PMID: 10624449. 1420: Goldsmith I, Lip GY, Khan F, Hutton R, Patel RL. Contamination of the surgeon's bare and gloved fingertips in cardiac operations. Int J Clin Pract. 1998 Nov-Dec;52(8):529-32. PubMed PMID: 10622048. 1421: Davis RC, Hobbs FD, Lip GY. ABC of heart failure. History and epidemiology. BMJ. 2000 Jan 1;320(7226):39-42. Review. PubMed PMID: 10617530; PubMed Central PMCID: PMC1117316. 1422: Goldsmith I, Lip GY, Kaukuntla H, Patel RL. Hospital morbidity and mortality and changes in quality of life following mitral valve surgery in the elderly. J Heart Valve Dis. 1999 Nov;8(6):702-7. PubMed PMID: 10616251. 1423: Gibbs CR, Lip GY. Atrial fibrillation and ethnicity. Circulation. 1999 Dec 21;100(25):e153. PubMed PMID: 10604919. 178 1424: Landray MJ, Sagar G, Murray S, Beevers M, Beevers DG, Lip GY. White coat hypertension and carotid atherosclerosis. Blood Press. 1999;8(3):134-40. PubMed PMID: 10595690. 1425: Gibbs CR, Lip GY, Beevers DG. Angioedema due to ACE inhibitors: increased risk in patients of African origin. Br J Clin Pharmacol. 1999 Dec;48(6):861-5. PubMed PMID: 10594491; PubMed Central PMCID: PMC2014308. 1426: Spencer CG, Lip GY, Beevers DG. Recurrent malignant hypertension: a report of two cases and review of the literature. J Intern Med. 1999 Nov;246(5):513-6. Review. PubMed PMID: 10583722. 1427: Feinberg WM, Pearce LA, Hart RG, Cushman M, Cornell ES, Lip GY, Bovill EG. Markers of thrombin and platelet activity in patients with atrial fibrillation: correlation with stroke among 1531 participants in the stroke prevention in atrial fibrillation III study. Stroke. 1999 Dec;30(12):2547-53. PubMed PMID: 10582976. 1428: Wong PS, Singh SP, Watson RD, Lip GY. Management of pulmonary thrombo-embolism using catheter manipulation: a report of four cases and review of the literature. Postgrad Med J. 1999 Dec;75(890):737-41. Review. PubMed PMID: 10567603; PubMed Central PMCID: PMC1741447. 1429: Spencer CG, Lip GY. Left ventricular hypertrophy and its regression: the prothrombic state in hypertension may be involved in its pathophysiology and altered by therapy. Am J Hypertens. 1999 Oct;12(10 Pt 1):1048-9. PubMed PMID: 10560793. 1430: Lip GY. Assessment of risk of thromboembolism in atrial fibrillation: which patients should be anticoagulated? Eur Heart J. 1999 Dec;20(23):1757-8. PubMed PMID: 10562485. 1431: Lip GY, Singh SP, de Giovanni J. Percutaneous balloon valvuloplasty for congenital pulmonary valve stenosis in adults. Clin Cardiol. 1999 Nov;22(11):733-7. PubMed PMID: 10554689. 1432: Blann AD, Li-Saw-Hee F, Lip GY, Minamino T, Kitakaze M, Sanada S, Asanuma 179 H, Kurotobi T, Koretsune Y, Fukunami M, Kuzuya T, Hoki N, Hori M. Increased membrane and soluble P-selectin in atrial fibrillation. Circulation. 1999 Oct 26;100(17):e86-7. PubMed PMID: 10534479. 1433: Lip GY. Atrial fibrillation and mortality. Eur Heart J. 1999 Nov;20(21):1525-7. PubMed PMID: 10529317. 1434: Goldsmith I, Lip GY, Emsden K, Nugent A, Patel RL. Hyperlipidaemia management after primary coronary artery bypass surgery: a survey of patients and general practitioners. J Cardiovasc Risk. 1999 Aug;6(4):263-7. PubMed PMID: 10501279. 1435: Edmunds E, Spencer CG, Lip GY. Left ventricular hypertrophy in the population. Eur Heart J. 1999 Oct;20(20):1514-5. PubMed PMID: 10493850. 1436: Gibbs CR, Lip GY. Ethnicity and heart failure. Eur Heart J. 1999 Oct;20(19):1436-7. PubMed PMID: 10487806. 1437: Lip GY, Blann AD, Beevers DG. Prothrombotic factors, endothelial function and left ventricular hypertrophy in isolated systolic hypertension compared with systolic-diastolic hypertension. J Hypertens. 1999 Aug;17(8):1203-7. PubMed PMID: 10466477. 1438: Blann A, Kumar P, Krupinski J, McCollum C, Beevers DG, Lip GY. Soluble intercelluar adhesion molecule-1, E-selectin, vascular cell adhesion molecule-1 and von Willebrand factor in stroke. Blood Coagul Fibrinolysis. 1999 Jul;10(5):277-84. PubMed PMID: 10456619. 1439: Lip GY. Antihypertensive agents and left ventricular hypertrophy with 'usual' care in the population setting. J Hum Hypertens. 1999 Aug;13(8):497-8. Review. PubMed PMID: 10455468. 1440: Lip GY, Rathore VS, Katira R, Singh SP, Watson RD. Changes in renal function with percutaneous transluminal coronary angioplasty. Int J Cardiol. 1999 Jul 31;70(2):127-31. PubMed PMID: 10454300. 1441: Lip GY, Douglas M, Gupta A, Beevers DG. Urinary sodium excretion and blood 180 pressure in chronic psychiatric in-patients. J Hum Hypertens. 1999 Jul;13(7):461-6. PubMed PMID: 10449210. 1442: Lip GY, Ferner RE. Diuretic therapy for hypertension: a cancer risk? J Hum Hypertens. 1999 Jul;13(7):421-3. Review. PubMed PMID: 10449203. 1443: Goldsmith I, Lip GY, Tsang G, Patel RL. Comparison of primary coronary artery bypass surgery in a British Indo-Asian and white Caucasian population. Eur Heart J. 1999 Aug;20(15):1094-100. PubMed PMID: 10413639. 1444: Gibbs CR, Beevers DG, Lip GY. The management of hypertensive disease in black patients. QJM. 1999 Apr;92(4):187-92. Review. PubMed PMID: 10396605. 1445: Lydakis C, Lip GY, Beevers M, Beevers DG. Atenolol and fetal growth in pregnancies complicated by hypertension. Am J Hypertens. 1999 Jun;12(6):541-7. PubMed PMID: 10371362. 1446: Spencer CG, Lip GY. Left ventricular hypertrophy and sudden death. J Am Coll Cardiol. 1999 Jun;33(7):2089. PubMed PMID: 10362223. 1447: Goldsmith IR, Lip GY, Kumar PP, Patel RL. A survey of hospital morbidity, mortality and quality of life following coronary artery bypass surgery in a UK Indo-Asian population. Int J Clin Pract. 1999 Jan-Feb;53(1):9-14. PubMed PMID: 10344059. 1448: Li-Saw-Hee FL, Lip GY. Atrial fibrillation, thromboembolism and antithrombotic therapy. Int J Clin Pract. 1999 Mar;53(2):110-7. Review. PubMed PMID: 10344046. 1449: Krupinski J, Vodovotz Y, Li C, Slowik A, Beevers D, Flanders KC, Lip G, Kumar P, Szczudlik A. Inducible nitric oxide production and expression of transforming growth factor-beta1 in serum and CSF after cerebral ischaemic stroke in man. Nitric Oxide. 1998;2(6):442-53. PubMed PMID: 10342487. 1450: Lip GY. Thromboprophylaxis for atrial fibrillation. Lancet. 1999 May 8;353(9164):1620-1. PubMed PMID: 10334280. 181 1451: Blann AD, Lip GY. Cell adhesion molecules in cardiovascular disease: what can soluble levels tell us? Heart. 1999 Jan;81(1):101-2. PubMed PMID: 10328667; PubMed Central PMCID: PMC1728892. 1452: Blann AD, Lip GY, Fijnheer R. Significance of soluble P-selectin, von Willebrand factor, and other adhesion molecules in hypercholesterolemia and peripheral artery disease. Circulation. 1999 May 11;99(18):2478-9. PubMed PMID: 10318743. 1453: Li-Saw-Hee FL, Blann AD, Goldsmith I, Lip GY. Indexes of hypercoagulability measured in peripheral blood reflect levels in intracardiac blood in patients with atrial fibrillation secondary to mitral stenosis. Am J Cardiol. 1999 Apr 15;83(8):1206-9. PubMed PMID: 10215285. 1454: Lip GY, Gibbs CR. Does heart failure confer a hypercoagulable state? Virchow's triad revisited. J Am Coll Cardiol. 1999 Apr;33(5):1424-6. Review. PubMed PMID: 10193748. 1455: Goldsmith I, Lip GY, Patel RL. Evaluation of the Sorin bicarbon bileaflet valve in 488 patients (519 prostheses). Am J Cardiol. 1999 Apr 1;83(7):1069-74. PubMed PMID: 10190522. 1456: Lydakis C, Beevers DG, Beevers M, Lip GY. Obstetric and neonatal outcome following chronic hypertension in pregnancy among different ethnic groups. QJM. 1998 Dec;91(12):837-44. PubMed PMID: 10024949. 1457: Lip GY. Thromboprophylaxis for atrial fibrillation. Lancet. 1999 Jan 2;353(9146):4-6. Erratum in: Lancet 1999 Jun 5;353(9168):1978. PubMed PMID: 10023940. 1458: Landray MJ, Lip GY. White coat hypertension: a recognised syndrome with uncertain implications. J Hum Hypertens. 1999 Jan;13(1):5-8. Review. PubMed PMID: 9928745. 1459: Lydakis C, Chaudary AY, Lip GY. The 'vasovagal effect' of nitrates: an under-recognised complication of nitrate use. Int J Clin Pract. 1998 Sep;52(6):418-21. Review. PubMed PMID: 9894380. 182 1460: Lip GY, Beevers DG. Why beta-blockers are good for some patients with hypertension: a case study of a hypertensive patient with adrenergic paroxysmal atrial fibrillation. J Hum Hypertens. 1998 Dec;12(12):867-8. PubMed PMID: 9883711. 1461: Lip GY. Beta-blockers in hypertension: to reappraise or to call a halt? J Hum Hypertens. 1998 Dec;12(12):799-801. PubMed PMID: 9883698. 1462: Blann AD, Lip GY. Raised levels of intercellular adhesion molecule-1 and vascular cell adhesion molecule-1 in the plasma of patients with ischaemic heart disease and hyperlipidaemia. Atherosclerosis. 1998 Nov;141(1):177-8. PubMed PMID: 9863551. 1463: Lip GY, Edmunds E, Beevers DG. Lack of relationship between left ventricular mass and serum cholesterol in hypertensives. J Hypertens. 1998 Nov;16(11):1703-4. PubMed PMID: 9856374. 1464: Li-Saw-Hee FL, Lip GY. Falls in old age: inevitable or preventable? Scott Med J. 1998 Oct;43(5):133-4. PubMed PMID: 9854296. 1465: Lip GY, Beevers M, Beevers DG. The 'Birmingham Hypertension Square' for the optimum choice of add-in drugs in the management of resistant hypertension. J Hum Hypertens. 1998 Nov;12(11):761-3. PubMed PMID: 9844947. 1466: Mzimba ZS, Beevers DG, Lip GY. Antihypertensive therapy before, during, and after stroke. Basic Res Cardiol. 1998;93 Suppl 2:59-62. Review. PubMed PMID: 9833165. 1467: Lip PL, Jones AF, Price N, Headon M, Beevers DG, Lip GY. Do intraocular angiotensin II levels, plasma prothrombotic factors and endothelial dysfunction contribute to proliferative diabetic retinopathy? Acta Ophthalmol Scand. 1998 Oct;76(5):533-6. PubMed PMID: 9826034. 1468: Beevers DG, Lip GY. Is uric acid really an independent cardiovascular risk factor? Lancet. 1998 Nov 7;352(9139):1556. PubMed PMID: 9820335. 183 1469: Lip GY, Blann AD. Prothrombin fragment 1+2 is a risk factor for myocardial infarction in treated hypertensive men. J Hypertens. 1998 Oct;16(10):1557-9. PubMed PMID: 9814630. 1470: Lip GY, Ray KK, Shiu MF. Coronary spasm in acute myocardial infarction. Heart. 1998 Aug;80(2):197-9. PubMed PMID: 9813570; PubMed Central PMCID: PMC1728776. 1471: Lip GY, Blann AD. Antihypertensive drug treatment and fibrinolytic function. Am J Hypertens. 1998 Oct;11(10):1266-7. Review. PubMed PMID: 9799046. 1472: Felmeden D, Lip GY. Anomalous origin of the left coronary artery. Int J Clin Pract. 1998 Jul-Aug;52(5):351. PubMed PMID: 9796571. 1473: Lip GY, Li-Saw-Hee FL. Does hypertension confer a hypercoagulable state? J Hypertens. 1998 Jul;16(7):913-6. Review. PubMed PMID: 9794730. 1474: Goldsmith I, Lip GY, Mukundan S, Rosin MD. Experience with low-dose aspirin as thromboprophylaxis for the Tissuemed porcine aortic bioprosthesis: a survey of five years' experience. J Heart Valve Dis. 1998 Sep;7(5):574-9. PubMed PMID: 9793859. 1475: Beevers DG, Lip GY. JNC-VI: a view from the United Kingdom. J Hum Hypertens. 1998 Sep;12(9):649-51. Review. PubMed PMID: 9783500. 1476: Lip GY, Singh SP, Beevers DG. Aortic coarctation diagnosed after hypertension in pregnancy. Am J Obstet Gynecol. 1998 Sep;179(3 Pt 1):814-5. PubMed PMID: 9757996. 1477: Landray MJ, Nuttall SL, Lydakis C, Martin U, Maxwell SR, Lip GY. Oxidative stress after thrombolysis. Lancet. 1998 Sep 19;352(9132):960. PubMed PMID: 9752824. 1478: Lip GY, Gibbs CR. Antithrombotics for left-ventricular impairment. Lancet. 1998 Sep 5;352(9130):817-8. PubMed PMID: 9737312. 184 1479: Landray MJ, Sagar G, Muskin J, Murray S, Holder RL, Lip GY. Association of atherogenic low-density lipoprotein subfractions with carotid atherosclerosis. QJM. 1998 May;91(5):345-51. PubMed PMID: 9709468. 1480: Lydakis C, Lip GY. Microalbuminuria and cardiovascular risk. QJM. 1998 Jun;91(6):381-91. Review. PubMed PMID: 9709456. 1481: Lip GY, Gibbs CR, Beevers DG. Ambulatory blood pressure monitoring and stroke: more questions than answers. Stroke. 1998 Aug;29(8):1495-7. PubMed PMID: 9707182. 1482: Lip GY, Bawden L, Hodson R, Rutland E, Snatchfold J, Beevers DG. Atrial fibrillation amongst the Indo-Asian general practice population. The West Birmingham Atrial Fibrillation Project. Int J Cardiol. 1998 Jul 1;65(2):187-92. PubMed PMID: 9706815. 1483: Lip GY, Lydakis C, Zarifis J, Messerli FH. Regression of LVH or improved prognosis (or both): what is the question? J Hum Hypertens. 1998 Jul;12(7):423-5. Review. PubMed PMID: 9702926. 1484: Blann AD, Lip GY. Endothelial integrity, soluble adhesion molecules and platelet markers in type 1 diabetes mellitus. Diabet Med. 1998 Aug;15(8):634-42. Review. PubMed PMID: 9702464. 1485: Blann AD, Lip GY. The endothelium in atherothrombotic disease: assessment of function, mechanisms and clinical implications. Blood Coagul Fibrinolysis. 1998 Jun;9(4):297-306. Review. PubMed PMID: 9690800. 1486: Lip PL, Blann AD, Jones AF, Lip GY. Abnormalities in haemorheological factors and lipoprotein (a) in retinal vascular occlusion: implications for increased vascular risk. Eye (Lond). 1998;12 ( Pt 2):245-51. PubMed PMID: 9683948. 1487: Li-Saw-Hee FL, Lip GY. Digoxin revisited. QJM. 1998 Apr;91(4):259-64. Review. PubMed PMID: 9666948. 185 1488: Gibbs CR, Lip GY. Do we still need dipyridamole? Br J Clin Pharmacol. 1998 Apr;45(4):323-8. Review. PubMed PMID: 9578178; PubMed Central PMCID: PMC1873966. 1489: Lydakis C, Kerr H, Hutchings K, Lip GY. Women's awareness of, and attitudes towards, hormone replacement therapy: ethnic differences and effects of age and education. Int J Clin Pract. 1998 Jan-Feb;52(1):7-12. PubMed PMID: 9536560. 1490: Gibbs CR, Li-Saw-Hee FL, Lip GY. Up to date review of the secondary preventive measures for recurrent ischaemic stroke and transient ischaemic episodes. Scott Med J. 1998 Feb;43(1):6. PubMed PMID: 9533251. 1491: Jones AF, Lip GY. Lipoprotein (a): more than just a bystander in the pathophysiology of hypertension? J Hum Hypertens. 1998 Feb;12(2):75-7. PubMed PMID: 9504348. 1492: Lydakis C, Hollinrake K, Lip GY. An unusual cause of palpitations requiring atrioventricular node ablation and pacemaker therapy. Blood Press. 1997 Nov;6(6):368-71. PubMed PMID: 9495663. 1493: Blann AD, Lip GY. Hyperhomocysteinaemia: a cardiovascular risk factor needing a large intervention trial? Int J Cardiol. 1997 Dec 19;62(3):217-9. PubMed PMID: 9476681. 1494: Cook PJ, Honeybourne D, Lip GY, Beevers DG, Wise R, Davies P. Chlamydia pneumoniae antibody titers are significantly associated with acute stroke and transient cerebral ischemia: the West Birmingham Stroke Project. Stroke. 1998 Feb;29(2):404-10. PubMed PMID: 9472881. 1495: Wong PS, Hee FL, Lip GY. Atrial fibrillation and the thyroid. Heart. 1997 Dec;78(6):623-4. PubMed PMID: 9470888; PubMed Central PMCID: PMC1892318. 1496: Lip GY, Beevers DG. 'Reverse dipping' on ambulatory blood pressure monitoring. J Hum Hypertens. 1997 Dec;11(12):821-2. PubMed PMID: 9468010. 1497: Blann AD, Lip GY. Platelets and hypertension: the pressure is on the clot. J Hum Hypertens. 1997 Dec;11(12):763-4. PubMed PMID: 9468000. 186 1498: Cook PJ, Lip GY, Davies P, Beevers DG, Wise R, Honeybourne D. Chlamydia pneumoniae antibodies in severe essential hypertension. Hypertension. 1998 Feb;31(2):589-94. PubMed PMID: 9461226. 1499: Lip GY, Beevers M, Beevers DG. Malignant hypertension in young women is related to previous hypertension in pregnancy, not oral contraception. QJM. 1997 Sep;90(9):571-5. PubMed PMID: 9349449. 1500: Lydakis C, Efstratopoulos A, Lip GY. Microalbuminuria in hypertension: is it up to measure? J Hum Hypertens. 1997 Nov;11(11):695-7. Review. PubMed PMID: 9416980. 1501: Lip GY. Atrial fibrillation in hypertension: under recognised or over diagnosed? J Hum Hypertens. 1997 Nov;11(11):691-3. Review. PubMed PMID: 9416979. 1502: Lip GY, Blann AD, Jones AF, Lip PL, Beevers DG. Relation of endothelium, thrombogenesis, and hemorheology in systemic hypertension to ethnicity and left ventricular hypertrophy. Am J Cardiol. 1997 Dec 15;80(12):1566-71. PubMed PMID: 9416937. 1503: Gibbs C, Blann AD, Lip GY. Thromboembolic risk and pacemakers. Lancet. 1997 Dec 13;350(9093):1780-1. PubMed PMID: 9413493. 1504: Lip GY, Beevers M, Beevers DG. Does renal function improve after diagnosis of malignant phase hypertension? J Hypertens. 1997 Nov;15(11):1309-15. PubMed PMID: 9383181. 1505: Hee FL, Wong PS, Lip GY. Atrial fibrillation begets trouble. Heart. 1997 Oct;78(4):421. PubMed PMID: 9404264; PubMed Central PMCID: PMC1892254. 1506: Felmeden D, Lip GY, Beevers DG. Fibromuscular dysplasia. J Hum Hypertens. 1997 Oct;11(10):687-8. PubMed PMID: 9400912. 1507: Blann A, Lip G. Assessment of endothelial function using plasma markers. Heart. 1997 Sep;78(3):321-2. PubMed PMID: 9391304; PubMed Central PMCID: PMC484944. 187 1508: Lip GY, Churchill D, Beevers M, Auckett A, Beevers DG. Angiotensin-converting-enzyme inhibitors in early pregnancy. Lancet. 1997 Nov 15;350(9089):1446-7. PubMed PMID: 9371172. 1509: Blann AD, Lip GY, Islim IF, Beevers DG. Evidence of platelet activation in hypertension. J Hum Hypertens. 1997 Sep;11(9):607-9. PubMed PMID: 9364284. 1510: Maxwell SR, Lip GY. Free radicals and antioxidants in cardiovascular disease. Br J Clin Pharmacol. 1997 Oct;44(4):307-17. Review. PubMed PMID: 9354304; PubMed Central PMCID: PMC2042858. 1511: Lip GY, Blann AD, Jones AF, Beevers DG. Effects of hormone-replacement therapy on hemostatic factors, lipid factors, and endothelial function in women undergoing surgical menopause: implications for prevention of atherosclerosis. Am Heart J. 1997 Oct;134(4):764-71. PubMed PMID: 9351746. 1512: Blann AD, Lip GY. Coronary risk factors, endothelial function, and atherosclerosis: a review. Clin Cardiol. 1997 Oct;20(10):822, 824. PubMed PMID: 9377815. 1513: Li-Saw-Hee FL, Blann AD, Lip GY. The detection of endothelial dysfunction in patients with essential hypertension. Int J Cardiol. 1997 Sep 19;61(2):171-4. PubMed PMID: 9314211. 1514: Lip GY, Beevers DG. Interpretation of IST and CAST stroke trials. International Stroke Trial. Chinese Acute Stroke Trial. Lancet. 1997 Aug 9;350(9075):442-3; author reply 443-4. PubMed PMID: 9259676. 1515: Lip GY, Beevers DG. Can we treat coronary artery disease with antibiotics? Lancet. 1997 Aug 9;350(9075):378-9. PubMed PMID: 9259646. 1516: Katira R, Rathore VS, Lip GY, Singh SP. Coarctation of aorta. J Hum Hypertens. 1997 Aug;11(8):537-8. PubMed PMID: 9322837. 1517: Blann AD, Lip GY. Relation between endothelial-cell activation and 188 infection, inflammation, and infarction. Lancet. 1997 Jul 26;350(9073):293-4. PubMed PMID: 9242825. 1518: Lip GY. Can we treat hypertensive menopausal women with hormone replacement therapy? J Hum Hypertens. 1997 Jul;11(7):397-9. PubMed PMID: 9283053. 1519: Lip GY. Exacerbation of atherosclerosis by hypertension: potential mechanisms and clinical implications. Arch Intern Med. 1997 Jun 9;157(11):1265-6. PubMed PMID: 9183240. 1520: Lip G, Zarifis J, Beevers DG. Acute admissions with heart failure to a district general hospital serving a multiracial population. Int J Clin Pract. 1997 Jun;51(4):223-7. PubMed PMID: 9287263. 1521: Lip PL, Lip GY, Beevers DG. Fundal changes in malignant hypertension. J Hum Hypertens. 1997 Jun;11(6):395-6. PubMed PMID: 9249235. 1522: Beevers DG, Lip GY. Angiotensin II receptor antagonists, elite drugs (or not) for patients with heart failure or hypertension? J Hum Hypertens. 1997 Jun;11(6):329-30. PubMed PMID: 9249225. 1523: Blann AD, Lip GY, Beevers DG, McCollum CN. Soluble P-selectin in atherosclerosis: a comparison with endothelial cell and platelet markers. Thromb Haemost. 1997 Jun;77(6):1077-80. PubMed PMID: 9241735. 1524: Lip GY. Does paroxysmal atrial fibrillation confer a paroxysmal thromboembolic risk? Lancet. 1997 May 31;349(9065):1565-6. PubMed PMID: 9174554. 1525: Lip GY, Beevers M, Churchill D, Shaffer LM, Beevers DG. Effect of atenolol on birth weight. Am J Cardiol. 1997 May 15;79(10):1436-8. PubMed PMID: 9165181. 1526: Lip GY, Golding DJ, Nazir M, Beevers DG, Child DL, Fletcher RI. A survey of atrial fibrillation in general practice: the West Birmingham Atrial Fibrillation Project. Br J Gen Pract. 1997 May;47(418):285-9. PubMed PMID: 9219403; PubMed Central PMCID: PMC1313001. 189 1527: Lip GY, Blann A. von Willebrand factor: a marker of endothelial dysfunction in vascular disorders? Cardiovasc Res. 1997 May;34(2):255-65. Review. PubMed PMID: 9205537. 1528: Lip GY. Hypercoagulability and haemodynamic abnormalities in atrial fibrillation. Heart. 1997 May;77(5):395-6. PubMed PMID: 9196404; PubMed Central PMCID: PMC484756. 1529: Wong PS, Lip GY, Beevers DG. Hormone replacement therapy with conjugated estrogens and high blood pressure: response to Dr. Jespersen. Am J Hypertens. 1997 May;10(5 Pt 1):579. PubMed PMID: 9160772. 1530: Lip GY, Blann AD. Plasma thrombomodulin in atherosclerosis and its risk factors. Am J Med. 1997 Apr;102(4):423-5. PubMed PMID: 9217630. 1531: Lip GY. The left atrium in hypertension, an appendage often forgotten. J Hum Hypertens. 1997 Mar;11(3):145-7. Review. PubMed PMID: 9175565. 1532: Zarifis J, Beevers G, Lip GY. Acute admissions with atrial fibrillation in a British multiracial hospital population. Br J Clin Pract. 1997 Mar;51(2):91-6. PubMed PMID: 9158252. 1533: Lip GY, Wasfi M, Halim M, Singh H. Percutaneous balloon valvuloplasty of stenosed mitral bioprosthesis. Int J Cardiol. 1997 Mar;59(1):97-100. PubMed PMID: 9080032. 1534: Blann AD, Lip GY. Hypothesis: is soluble P-selectin a new marker of platelet activation? Atherosclerosis. 1997 Feb 10;128(2):135-8. Review. PubMed PMID: 9050769. 1535: Maxwell SR, Lip GY. Reperfusion injury: a review of the pathophysiology, clinical manifestations and therapeutic options. Int J Cardiol. 1997 Jan 31;58(2):95-117. Review. PubMed PMID: 9049675. 1536: Lip GY, Beevers DG. Doctors, nurses, pharmacists and patients--the Rational Evaluation and Choice in Hypertension (REACH) survey of hypertension care delivery. Blood Press Suppl. 1997;1:6-10. PubMed PMID: 9285101. 190 1537: Lip GY, Zarifis J, Farooqi IS, Page A, Sagar G, Beevers DG. Ambulatory blood pressure monitoring in acute stroke. The West Birmingham Stroke Project. Stroke. 1997 Jan;28(1):31-5. PubMed PMID: 8996484. 1538: Lip GY. Intracardiac thrombus formation in cardiac impairment: the role of anticoagulant therapy. Postgrad Med J. 1996 Dec;72(854):731-8. Review. PubMed PMID: 9015466; PubMed Central PMCID: PMC2398676. 1539: Lip GY, Adeotoye OA, Zarifis J, Singh SP, Watson RD, Beevers DG. Ambulatory blood pressure monitoring in patients with single chamber ventricular pacemakers (VVI pacing mode). Am J Hypertens. 1996 Dec;9(12 Pt 1):1240-1. PubMed PMID: 8972899. 1540: Lip GY, Rumley A, Dunn FG, Lowe GD. Thrombogenesis in mitral regurgitation and aortic stenosis. Angiology. 1996 Dec;47(12):1117-25. PubMed PMID: 8956663. 1541: Lip GY. Commentary: do angiotensin II receptor antagonists regress left ventricular hypertrophy? J Hum Hypertens. 1996 Nov;10(11):725-7. Review. PubMed PMID: 9004101. 1542: Lip GY, Cader MZ, Lee F, Munir SM, Beevers DG. Ethnic differences in pre-admission levels of physical activity in patients admitted with myocardial infarction. Int J Cardiol. 1996 Oct 11;56(2):169-75. PubMed PMID: 8894789. 1543: Beevers DG, Lip GY. Does non-malignant essential hypertension cause renal damage? A clinician's view. J Hum Hypertens. 1996 Oct;10(10):695-9. Review. PubMed PMID: 9004097. 1544: Lip GY. Antithrombotic therapy for non-rheumatic atrial fibrillation. QJM. 1996 Oct;89(10):799-800; author reply 801-2. PubMed PMID: 8944236. 1545: Rajman I, Lip GY, Cramb R, Maxwell SR, Zarifis J, Beevers DG, Kendall MJ. Adverse change in low-density lipoprotein subfractions profile with oestrogen-only hormone replacement therapy. QJM. 1996 Oct;89(10):771-8. PubMed PMID: 8944233. 191 1546: Cook PJ, Lip GY. Infectious agents and atherosclerotic vascular disease. QJM. 1996 Oct;89(10):727-35. Review. PubMed PMID: 8944228. 1547: Lip GY. Intravenous amiodarone in treatment of recent-onset atrial fibrillation. J Am Coll Cardiol. 1996 Oct;28(4):1080-2. PubMed PMID: 8837590. 1548: Lip GY, Gupta J, Gill JS, Singh SP. Sarcoid heart disease: a rare cause of chest pain and malignant cardiac arrhythmia in a young Asian man. A case report. Angiology. 1996 Sep;47(9):905-10. PubMed PMID: 8810658. 1549: Lip GY, Zarifis J, Beevers M, Beevers DG. Ambulatory blood pressure monitoring in atrial fibrillation. Am J Cardiol. 1996 Aug 1;78(3):350-3. PubMed PMID: 8759820. 1550: Lip GY, Lip PL, Zarifis J, Watson RD, Bareford D, Lowe GD, Beevers DG. Fibrin D-dimer and beta-thromboglobulin as markers of thrombogenesis and platelet activation in atrial fibrillation. Effects of introducing ultra-low-dose warfarin and aspirin. Circulation. 1996 Aug 1;94(3):425-31. PubMed PMID: 8759084. 1551: Lip GY, Beevers DG. Epidemiology of aortic aneurysm and peripheral vascular disease may show ethnic differences. BMJ. 1996 Jul 20;313(7050):173. PubMed PMID: 8688802; PubMed Central PMCID: PMC2351555. 1552: Lip GY, Hayter J, Makwana NV. Design and baseline characteristics of a hypertension intervention program in a South African village: patient awareness and understanding of their disease process are important. J Hum Hypertens. 1996 Jul;10(7):499. PubMed PMID: 8880568. 1553: Li Saw Hee FL, Lip GY. Case report: fatal verapamil overdosage despite intensive therapy and use of high dose intravenous calcium. J Hum Hypertens. 1996 Jul;10(7):495-6. PubMed PMID: 8880566. 1554: Zarifis J, Lip GY, Leatherdale B, Beevers G. Malignant hypertension in association with primary aldosteronism. Blood Press. 1996 Jul;5(4):250-4. PubMed PMID: 8809377. 192 1555: Lip GY, Roberts R, Gates S, Beevers M, Orsborn RC, Beevers DG. Editorial: combination therapy for systemic hypertension (15 September 1995). Am J Cardiol. 1996 Jul 1;78(1):129-30. PubMed PMID: 8712110. 1556: Lip GY, Beevers DG. Antagonism to calcium antagonists. Lancet. 1996 Jun 22;347(9017):1761. PubMed PMID: 8656915. 1557: Lip GY, Beevers G, Zarifis J, Singh SP. Value of ECGs in identifying heart failure due to left ventricular systolic dysfunction. ECGs are valuable in hospital as well as general practice. BMJ. 1996 May 4;312(7039):1161. PubMed PMID: 8620158; PubMed Central PMCID: PMC2350677. 1558: Lip GY, Lowe GD. Warfarin and aspirin as thromboprophylaxis in atrial fibrillation. Br J Clin Pharmacol. 1996 May;41(5):369-79. Review. PubMed PMID: 8735677; PubMed Central PMCID: PMC2042601. 1559: Lip GY, Beevers DG. Are calcium antagonists safe in hypertension? Postgrad Med J. 1996 Apr;72(846):193-4. PubMed PMID: 8733522; PubMed Central PMCID: PMC2398440. 1560: Lip GY, Lowe GD, Rumley A, Dunn FG. Fibrinogen and fibrin D-dimer levels in paroxysmal atrial fibrillation: evidence for intermediate elevated levels of intravascular thrombogenesis. Am Heart J. 1996 Apr;131(4):724-30. PubMed PMID: 8721646. 1561: Lip GY, Luscombe C, McCarry M, Malik I, Beevers G. Ethnic differences in public health awareness, health perceptions and physical exercise: implications for heart disease prevention. Ethn Health. 1996 Mar;1(1):47-53. PubMed PMID: 9395547. 1562: deGiovanni JV, Lip GY, Osman K, Mohan M, Islim IF, Gupta J, Watson RD, Singh SP. Percutaneous balloon dilatation of aortic coarctation in adults. Am J Cardiol. 1996 Feb 15;77(5):435-9. PubMed PMID: 8602580. 1563: Dodson PM, Lip GY, Eames SM, Gibson JM, Beevers DG. Hypertensive retinopathy: a review of existing classification systems and a suggestion for a simplified grading system. J Hum Hypertens. 1996 Feb;10(2):93-8. Review. PubMed PMID: 8867562. 193 1564: Lip GY, Zarifis J, Watson RD, Beevers DG. Physician variation in the management of patients with atrial fibrillation. Heart. 1996 Feb;75(2):200-5. PubMed PMID: 8673762; PubMed Central PMCID: PMC484261. 1565: Lip GH, Wise R, Beevers G. Association of Helicobacter pylori infection with coronary heart disease. Study shows association between H pylori infection and hypertension. BMJ. 1996 Jan 27;312(7025):250-1. PubMed PMID: 8563608; PubMed Central PMCID: PMC2350008. 1566: Lip GY, Beevers DG, Coope JR. ABC of atrial fibrillation. Atrial fibrillation in general and hospital practice. BMJ. 1996 Jan 20;312(7024):175-8. Review. PubMed PMID: 8563542; PubMed Central PMCID: PMC2349856. 1567: Lip GY, Watson RD, Singh SP. ABC of atrial fibrillation. Cardioversion of atrial fibrillation. BMJ. 1996 Jan 13;312(7023):112-5. Review. PubMed PMID: 8555897; PubMed Central PMCID: PMC2349751. 1568: Lip GY. Quality of service provision for anticoagulation in atrial fibrillation. Many patients are ineligible. BMJ. 1996 Jan 6;312(7022):51. PubMed PMID: 8555867; PubMed Central PMCID: PMC2349713. 1569: Lip GY, Lowe GD. ABC of atrial fibrillation. Antithrombotic treatment for atrial fibrillation. BMJ. 1996 Jan 6;312(7022):45-9. Review. PubMed PMID: 8555864; PubMed Central PMCID: PMC2349725. 1570: Lip GY, Vale JA. Does acetaminophen damage the heart? J Toxicol Clin Toxicol. 1996;34(2):145-7. Review. PubMed PMID: 8618245. 1571: Lip GY, Watson RD, Singh SP. ABC of atrial fibrillation. Drugs for atrial fibrillation. BMJ. 1995 Dec 16;311(7020):1631-4. Review. PubMed PMID: 8555811; PubMed Central PMCID: PMC2551512. 1572: Lip GY, Singh SP, Watson RD. ABC of atrial fibrillation. Investigation and non-drug management of atrial fibrillation. BMJ. 1995 Dec 9;311(7019):1562-5. Review. PubMed PMID: 8520405; PubMed Central PMCID: PMC2548185. 194 1573: Lip GY, Watson RD. ABC of atrial fibrillation. Differential diagnosis of atrial fibrillation. BMJ. 1995 Dec 2;311(7018):1495-8. Review. PubMed PMID: 8520345; PubMed Central PMCID: PMC2543742. 1574: Zarifis J, Lip GY, Beevers DG. Effects of discontinuing hormone replacement therapy in patients with uncontrolled hypertension. Am J Hypertens. 1995 Dec;8(12 Pt 1):1241-2. PubMed PMID: 8998259. 1575: Lip GY, Blann AD, Zarifis J, Beevers M, Lip PL, Beevers DG. Soluble adhesion molecule P-selectin and endothelial dysfunction in essential hypertension: implications for atherogenesis? A preliminary report. J Hypertens. 1995 Dec;13(12 Pt 2):1674-8. PubMed PMID: 8903631. 1576: Lip GY, Blann AD. von Willebrand factor and its relevance to cardiovascular disorders. Br Heart J. 1995 Dec;74(6):580-3. Review. PubMed PMID: 8541159; PubMed Central PMCID: PMC484109. 1577: Lip GY. The coagulation system is activated in idiopathic cardiomyopathy. J Am Coll Cardiol. 1995 Dec;26(7):1757-8. PubMed PMID: 7594116. 1578: Lip GY, Beevers DG, Singh SP, Watson RD. ABC of atrial fibrillation. Aetiology, pathophysiology, and clinical features. BMJ. 1995 Nov 25;311(7017):1425-8. Review. PubMed PMID: 8520281; PubMed Central PMCID: PMC2544381. 1579: Lip GY, Beevers DG. ABC of atrial fibrillation. History, epidemiology, and importance of atrial fibrillation. BMJ. 1995 Nov 18;311(7016):1361-3. Review. Erratum in: BMJ 1996 Jan 6;312(7022):49. PubMed PMID: 7496293; PubMed Central PMCID: PMC2551280. 1580: Lip GY. Does atrial fibrillation confer a hypercoagulable state? Lancet. 1995 Nov 18;346(8986):1313-4. Review. PubMed PMID: 7475767. 1581: Cook PJ, Honeybourne D, Lip GY, Beevers DG, Wise R. Chlamydia pneumoniae and acute arterial thrombotic disease. Circulation. 1995 Nov 15;92(10):3148-9. PubMed PMID: 7586293. 195 1582: Lip GY, Beevers M, Dodson PM, Beevers DG. Severe hypertension with lone bilateral papilloedema: a variant of malignant hypertension. Blood Press. 1995 Nov;4(6):339-42. PubMed PMID: 8746600. 1583: Lip GY, Beevers G, Zarifis J. Hormone replacement therapy and cardiovascular risk: the cardiovascular physicians' viewpoint. J Intern Med. 1995 Nov;238(5):389-99. Review. PubMed PMID: 7595178. 1584: Lip GY, Rumley A, Dunn FG, Lowe GD. Plasma fibrinogen and fibrin D-dimer in patients with atrial fibrillation: effects of cardioversion to sinus rhythm. Int J Cardiol. 1995 Oct;51(3):245-51. PubMed PMID: 8586473. 1585: Zarifis J, Lip GY, Ferner RE. Poisoning with anti-hypertensive drugs: methyldopa and clonidine. J Hum Hypertens. 1995 Oct;9(10):787-90. Review. PubMed PMID: 8576892. 1586: Lip GY, Ferner RE. Poisoning with anti-hypertensive drugs: angiotensin converting enzyme inhibitors. J Hum Hypertens. 1995 Sep;9(9):711-5. Review. PubMed PMID: 8551483. 1587: Lip GY, Lowe GD, Metcalfe MJ, Rumley A, Dunn FG. Effects of warfarin therapy on plasma fibrinogen, von Willebrand factor, and fibrin D-dimer in left ventricular dysfunction secondary to coronary artery disease with and without aneurysms. Am J Cardiol. 1995 Sep 1;76(7):453-8. PubMed PMID: 7653443. 1588: Lip GY, Beevers M, Potter JF, Beevers DG. Malignant hypertension in the elderly. QJM. 1995 Sep;88(9):641-7. PubMed PMID: 7583078. 1589: Lip GY, Lowe GD. Fibrin D-dimer: a useful clinical marker of thrombogenesis? Clin Sci (Lond). 1995 Sep;89(3):205-14. Review. PubMed PMID: 7493413. 1590: Lip GY, Beevers M, Beevers DG. Complications and survival of 315 patients with malignant-phase hypertension. J Hypertens. 1995 Aug;13(8):915-24. PubMed PMID: 8557970. 196 1591: Lip GY, Gupta J, Khan MM, Singh SP. Recurrent myocardial infarction with angina and normal coronary arteries. Int J Cardiol. 1995 Aug;51(1):65-71. PubMed PMID: 8522399. 1592: Lip GY, Jones AF. Lipoprotein (a) and vascular disease: thrombogenesis and atherogenesis. QJM. 1995 Aug;88(8):529-39. Review. PubMed PMID: 7648239. 1593: Lip GY. Cardioversion of atrial fibrillation. Postgrad Med J. 1995 Aug;71(838):457-65. Review. PubMed PMID: 7567751; PubMed Central PMCID: PMC2398208. 1594: Zarifis J, Beevers DG, Lip GY. Open access echocardiography. Hospital patients need open access echocardiography. BMJ. 1995 Jul 29;311(7000):326. PubMed PMID: 7633252; PubMed Central PMCID: PMC2550379. 1595: Lip GY, Zarifis J. Coagulation activity is increased in the left atrium of patients with mitral stenosis. J Am Coll Cardiol. 1995 Jul;26(1):302-3. PubMed PMID: 7797771. 1596: Lip GY, Ferner RE. Poisoning with anti-hypertensive drugs: alpha-adrenoceptor antagonists. J Hum Hypertens. 1995 Jul;9(7):523-6. Review. PubMed PMID: 7562879. 1597: Lip GY, Lowe GD, Metcalfe MJ, Rumley A, Dunn FG. Is diastolic dysfunction associated with thrombogenesis? A study of circulating markers of a prothrombotic state in patients with coronary artery disease. Int J Cardiol. 1995 Jun 2;50(1):31-42. Erratum in: Int J Cardiol 1995 Sep;51(2):205. PubMed PMID: 7558462. 1598: Lip GY, Singh SP. Nitrates and severe aortic stenosis. Br Heart J. 1995 Jun;73(6):586. PubMed PMID: 7626366; PubMed Central PMCID: PMC483930. 1599: Farooqi I, Beevers G, Lip GY. Insulin resistance, high prevalence of diabetes, and cardiovascular risk in immigrant Asians. Br Heart J. 1995 Jun;73(6):584. PubMed PMID: 7626363; PubMed Central PMCID: PMC483926. 1600: Lip GY, Lowe GD, Rumley A, Dunn FG. Increased markers of thrombogenesis in 197 chronic atrial fibrillation: effects of warfarin treatment. Br Heart J. 1995 Jun;73(6):527-33. PubMed PMID: 7626351; PubMed Central PMCID: PMC483914. 1601: Lip GY, Ferner RE. Poisoning with antihypertensive drugs: diuretics and potassium supplements. J Hum Hypertens. 1995 May;9(5):295-301. Review. PubMed PMID: 7623367. 1602: Sedgwick ML, Lip G, Rae AP, Cobbe SM. Chemical cardioversion of atrial fibrillation with intravenous dofetilide. Int J Cardiol. 1995 Apr;49(2):159-66. PubMed PMID: 7628887. 1603: Lip GY, Ferner RE. Poisoning with anti-hypertensive drugs: beta-adrenoceptor blocker drugs. J Hum Hypertens. 1995 Apr;9(4):213-21. Review. PubMed PMID: 7595901. 1604: Lip GY. Hormone replacement therapy and cardiovascular risk. Lancet. 1995 Mar 4;345(8949):585-6. PubMed PMID: 7776795. 1605: Lip GY, Malik I, Luscombe C, McCarry M, Beevers G. Dietary fat purchasing habits in whites, blacks and Asian peoples in England--implications for heart disease prevention. Int J Cardiol. 1995 Mar 3;48(3):287-93. PubMed PMID: 7782144. 1606: Lip GY, Ferner RE. Poisoning with anti-hypertensive drugs: calcium antagonists. J Hum Hypertens. 1995 Mar;9(3):155-61. Review. PubMed PMID: 7783095. 1607: Lip G, Beevers M, Churchill D, Beevers DG. Do clinicians prescribe HRT for hypertensive postmenopausal women? Br J Clin Pract. 1995 Mar-Apr;49(2):61-4. PubMed PMID: 7779644. 1608: Lip GY. Fibrinogen and cardiovascular disorders. QJM. 1995 Mar;88(3):155-65. Review. PubMed PMID: 7767665. 1609: Lip GY, Beevers DG. Alcohol, hypertension, coronary disease and stroke. Clin Exp Pharmacol Physiol. 1995 Mar;22(3):189-94. Review. PubMed PMID: 7554412. 1610: Lip GY, Balasubramaniam R, Maurice A, Beevers G. Health promotion in 198 general practice. Focus on modification of risk factors and patients' perception of lifestyle. BMJ. 1995 Feb 25;310(6978):533. PubMed PMID: 7888914; PubMed Central PMCID: PMC2548925. 1611: Lip GY, Beevers M, Zarifis J, Beevers G. Hormone replacement therapy is not a risk for venous thrombosis. Scott Med J. 1995 Feb;40(1):30. PubMed PMID: 7604241. 1612: Lip GY, Beevers M, Zarifis J, Beevers G. Seasonal variations in fatal pulmonary embolism. Malignant phase hypertension does not vary by season. BMJ. 1995 Jan 14;310(6972):129-30. PubMed PMID: 7833717; PubMed Central PMCID: PMC2548532. 1613: Lip GY, Zarifis J, Beevers M, Beevers DG. Duration of cough following cessation of ACE inhibitor therapy. Am J Hypertens. 1995 Jan;8(1):98. PubMed PMID: 7734107. 1614: Metcalfe MJ, Lip GY, Dargie HJ. Factors influencing coronary artery bypass graft patency. Cardiovasc Surg. 1994 Dec;2(6):679-85. Review. PubMed PMID: 7858984. 1615: Zarifis J, Beevers DG, Lip GY. Evidence of inadequate investigation and treatment of patients with heart failure. Br Heart J. 1994 Dec;72(6):593. PubMed PMID: 7857747; PubMed Central PMCID: PMC1025653. 1616: Farooqi I, Lip GY, Beevers DG. Sudden infant death syndrome among Asians in Britain. BMJ. 1994 Nov 5;309(6963):1232. PubMed PMID: 7695710; PubMed Central PMCID: PMC2541689. 1617: Lip GY, Beevers M, Beevers G. The failure of malignant hypertension to decline: a survey of 24 years' experience in a multiracial population in England. J Hypertens. 1994 Nov;12(11):1297-305. PubMed PMID: 7868878. 1618: Farooqi IS, Dar S, Farooqi S, Beevers DG, Lip GY. A comparative study of risk factors for acute myocardial infarction amongst men of Indo-origin in Trinidad and the UK. Int J Cardiol. 1994 Nov;47(1):45-9. PubMed PMID: 7868284. 199 1619: Lip GY, Metcalfe MJ. Have we identified the factors affecting prognosis following coronary artery bypass surgery? Br J Clin Pract. 1994 Nov-Dec;48(6):317-22. Review. PubMed PMID: 7848796. 1620: Lip GY, Beevers DG. Abnormalities of rheology and coagulation in hypertension. J Hum Hypertens. 1994 Sep;8(9):693-702. Review. PubMed PMID: 7807500. 1621: Air A, Lip GY, Beevers DG. Hormone replacement therapy. Attitudes of women should be considered. BMJ. 1994 Jul 16;309(6948):192. PubMed PMID: 8080577; PubMed Central PMCID: PMC2540724. 1622: Lip GY, Ferner RE. Overdose of diltiazem. BMJ. 1994 Jul 16;309(6948):193. PubMed PMID: 8044106; PubMed Central PMCID: PMC2540670. 1623: Lip GY, Beevers M, Churchill D, Beevers DG. Hormone replacement therapy and blood pressure in hypertensive women. J Hum Hypertens. 1994 Jul;8(7):491-4. PubMed PMID: 7932511. 1624: Lip GY, Tean KN, Dunn FG. Acute myocardial infarction: a rare complication of the thrombotic tendency in nephrotic syndrome. Br J Clin Pract. 1994 Jul-Aug;48(4):218-20. PubMed PMID: 7917806. 1625: Lip GY, Hogg KJ. Cardioversion of atrial fibrillation: how important is a long arrhythmia duration? Scott Med J. 1994 Jun;39(3):78-9. PubMed PMID: 8720769. 1626: Lip GY, Gammage MD, Beevers DG. Hypertension and the heart. Br Med Bull. 1994 Apr;50(2):299-321. Review. PubMed PMID: 8205460. 1627: Farooqi IS, Lip GY, Beevers DG. Bed sharing and smoking in the sudden infant death syndrome. BMJ. 1994 Jan 15;308(6922):204-5. PubMed PMID: 8312792; PubMed Central PMCID: PMC2542557. 1628: Lip GY, Tean KN, Dunn FG. Treatment of atrial fibrillation in a district general hospital. Br Heart J. 1994 Jan;71(1):92-5. PubMed PMID: 8297706; PubMed Central PMCID: PMC483620. 200 1629: Lip GY. Anticoagulation in patients with atrial fibrillation. No consensus among doctors. BMJ. 1993 Dec 4;307(6917):1493. PubMed PMID: 8281099; PubMed Central PMCID: PMC1679521. 1630: Balogun MO, Omotoso AB, Bell E, Lip GY, Gemmill JD, Hogg KJ, Dunn FG. An audit of emergency echocardiography in a district general hospital. Int J Cardiol. 1993 Aug;41(1):65-8. PubMed PMID: 8225674. 1631: Lip GY, Metcalfe MJ, Rae AP. Management of paroxysmal atrial fibrillation. Q J Med. 1993 Aug;86(8):467-72. Review. PubMed PMID: 8210304. 1632: Lip GY, Dunn FG. Unilateral pulmonary artery agenesis: a rare cause of haemoptysis and pleuritic chest pain. Int J Cardiol. 1993 Jul 1;40(2):121-5. PubMed PMID: 8349374. 1633: Lip GY, Metcalfe MJ, Dunn FG. Diagnosis and treatment of digoxin toxicity. Postgrad Med J. 1993 May;69(811):337-9. Review. PubMed PMID: 8346128; PubMed Central PMCID: PMC2399830. 1634: Lip GY, McColl KE, Moore MR. The acute porphyrias. Br J Clin Pract. 1993 Jan-Feb;47(1):38-43. Review. PubMed PMID: 8461247. 1635: Lip GY, Brodie MJ. Sudden death in epilepsy: an avoidable outcome? J R Soc Med. 1992 Oct;85(10):609-11. PubMed PMID: 1433037; PubMed Central PMCID: PMC1293687. 1636: Metcalfe MJ, Lip GY, Dunn FG. Misuse of calcium antagonists after myocardial infarction. Lancet. 1992 Aug 29;340(8818):545. PubMed PMID: 1354290. 1637: Lip GY, Metcalfe MJ. Adrenaline in allergic emergencies. BMJ. 1992 Aug 8;305(6849):366-7. PubMed PMID: 1489431; PubMed Central PMCID: PMC1882983. 1638: Dunn F, Lip G. Potential drug interactions in heart disease. Practitioner. 1992 Jul;236(1516):737-9. Review. PubMed PMID: 1360655. 201 1639: Dunn F, Lip G. Prescribing in heart disease. Practitioner. 1992 Jun;236(1515):669-71. PubMed PMID: 1454738. 1640: Lip GY, Metcalfe MJ. Adrenaline in allergic emergencies. BMJ. 1992 May 30;304(6839):1443. PubMed PMID: 1628033; PubMed Central PMCID: PMC1882151. 1641: Metcalfe MJ, Lip G, Dunn FG. Dipyridamole. Lancet. 1992 May 16;339(8803):1229. PubMed PMID: 1349956. 1642: Lip GY, Jaap AJ, McCruden DC. A presentation of anaplastic carcinoma of the thyroid with symptomatic intra-abdominal metastases. Br J Clin Pract. 1992 Summer;46(2):143-4. PubMed PMID: 1457306. 1643: Lip GY, Bramwell SP, Paterson PJ. Renal artery embolism: a rare cause of renal colic. J R Soc Med. 1991 Dec;84(12):748-9. Erratum in: J R Soc Med 1992 Jul;85(7):433. PubMed PMID: 1774756; PubMed Central PMCID: PMC1295529. 1644: Lip GY, McColl KE, Goldberg A, Moore MR. Smoking and recurrent attacks of acute intermittent porphyria. BMJ. 1991 Mar 2;302(6775):507. PubMed PMID: 2012848; PubMed Central PMCID: PMC1669610. 202