1: Paixão L, Oliveira J, Veríssimo A, Vinga S, Lourenço EC, Ventura MR, Kjos M, Veening JW, Fernandes VE, Andrew
PW, Yesilkaya H, Neves AR. Host Glycan Sugar-Specific Pathways in Streptococcus pneumonia: Galactose as a Key
Sugar in colonisation and infection. PLoS One. 2015 Mar 31;10(3):e0121042.
2: Gaspar P, Al-Bayati FA, Andrew PW, Neves AR, Yesilkaya H. Lactate dehydrogenase is the key enzyme for
pneumococcal pyruvate metabolism and pneumococcal survival in blood. Infect Immun. 2014 Dec;82(12):5099109.
3: Sandrini S, Alghofaili F, Freestone P, Yesilkaya H . Host stress hormone norepinephrine stimulates
pneumococcal growth, biofilm formation and virulence gene expression. BMC Microbiol. 2014 Jul 4;14:180. doi:
10.1186/1471-2180-14-180. PubMed PMID: 24996423; PubMed Central PMCID: PMC4105557.
4: Haste L, Hulland K, Bolton S, Yesilkaya H , McKechnie K, Andrew PW. Development and characterization of a
long-term murine model of Streptococcus pneumonia infection of the lower airways. Infect Immun. 2014
Aug;82(8):3289-98.
5: Yesilkaya H , Andisi VF, Andrew PW, Bijlsma JJ. Streptococcus pneumoniae and reactive oxygen species: an
unusual approach to living with radicals. Trends Microbiol. 2013 Apr;21(4):187-95. doi: 10.1016/j.tim.2013.01.004.
Epub 2013 Feb 13. Review. PubMed PMID: 23415028.
6: Hajaj B, Yesilkaya H , Benisty R, David M, Andrew PW, Porat N. Thiol peroxidase is an important component of
Streptococcus pneumoniae in oxygenated environments. Infect Immun. 2012 Dec;80(12):4333-43. doi:
10.1128/IAI.00126-12. Epub 2012 Oct 1. PubMed PMID: 23027531; PubMed Central PMCID: PMC3497430.
7: Kinjo Y, Illarionov P, Vela JL, Pei B, Girardi E, Li X, Li Y, Imamura M, Kaneko Y, Okawara A, Miyazaki Y, GómezVelasco A, Rogers P, Dahesh S, Uchiyama S, Khurana A, Kawahara K, Yesilkaya H , Andrew PW, Wong CH,
Kawakami K, Nizet V, Besra GS, Tsuji M, Zajonc DM, Kronenberg M. Invariant natural killer T cells recognize
glycolipids from pathogenic Gram-positive bacteria. Nat Immunol. 2011 Sep 4;12(10):966-74. doi:
10.1038/ni.2096. PubMed PMID: 21892173; PubMed Central PMCID: PMC3178673.
8: Bonnet M, Pardini M, Meacci F, Orrù G, Yesilkaya H , Jarosz T, Andrew PW, Barer M, Checchi F, Rinder H, Orefici
G, Rüsch-Gerdes S, Fattorini L, Oggioni MR, Melzer J, Niemann S, Varaine F. Treatment of tuberculosis in a region
with high drug resistance: outcomes, drug resistance amplification and re-infection. PLoS One. 2011;6(8):e23081.
doi: 10.1371/journal.pone.0023081. Epub 2011 Aug 23. PubMed PMID: 21886778; PubMed Central PMCID:
PMC3160294.
9: Shafeeq S, Yesilkaya H , Kloosterman TG, Narayanan G, Wandel M, Andrew PW, Kuipers OP, Morrissey JA. The
cop operon is required for copper homeostasis and contributes to virulence in Streptococcus pneumoniae. Mol
Microbiol. 2011 Sep;81(5):1255-70. doi: 10.1111/j.1365-2958.2011.07758.x. Epub 2011 Jul 19. PubMed PMID:
21736642.
10: Terra VS, Homer KA, Rao SG, Andrew PW, Yesilkaya H . Characterization of novel beta-galactosidase activity
that contributes to glycoprotein degradation and virulence in Streptococcus pneumoniae. Infect Immun. 2010
Jan;78(1):348-57. doi: 10.1128/IAI.00721-09. Epub 2009 Oct 19. PubMed PMID: 19841081; PubMed Central
PMCID: PMC2798215.
11: Bortoni ME, Terra VS, Hinds J, Andrew PW, Yesilkaya H . The pneumococcal response to oxidative stress
includes a role for Rgg. Microbiology. 2009 Dec;155(Pt 12):4123-34. doi: 11.1099/mic.0.028282-0. Epub 2009 Sep
17. PubMed PMID: 19762446; PubMed Central PMCID: PMC2885668.
12: Yesilkaya H , Spissu F, Carvalho SM, Terra VS, Homer KA, Benisty R, Porat N, Neves AR, Andrew PW. Pyruvate
formate lyase is required for pneumococcal fermentative metabolism and virulence. Infect Immun. 2009
Dec;77(12):5418-27. doi: 10.1128/IAI.00178-09. Epub 2009 Sep 14. PubMed PMID: 19752030; PubMed Central
PMCID: PMC2786486.
continued/
13: Pardini M, Niemann S, Varaine F, Iona E, Meacci F, Orrù G, Yesilkaya H , Jarosz T, Andrew P, Barer M, Checchi
F, Rinder H, Orefici G, Rüsch-Gerdes S, Fattorini L, Oggioni MR, Bonnet M. Characteristics of drug-resistant
tuberculosis in Abkhazia (Georgia), a high-prevalence area in Eastern Europe. Tuberculosis (Edinb). 2009
Jul;89(4):317-24. doi: 10.1016/j.tube.2009.04.002. Epub 2009 Jun 17. PubMed PMID: 19539531.
14: Yesilkaya H , Manco S, Kadioglu A, Terra VS, Andrew PW. The ability to utilize mucin affects the regulation of
virulence gene expression in Streptococcus pneumoniae. FEMS Microbiol Lett. 2008 Jan;278(2):231-5. Epub 2007
Dec 5. PubMed PMID: 18053067.
15: Pardini, M., Varaine, F., Hewison, C., Iona, E., Pataracchia, M., Orefici, G., Fattorini, L., Oggioni, M.R., Meacci,
F., D'Amato, V., Andrew, P.W., Barer, M., Yesilkaya, H., Rinder, H., Rüsch-Gerdes, S., Niemann, S., Orrù, G.,
Varaine, F., Bonnet, M., Jarosz, T. Pyrazinamide resistance in multidrug-resistant strains of Mycobacterium
tuberculosis isolated in Abkhazia [2] (2007) Journal of Chemotherapy, 19 (1), pp. 106-107.
16: Yesilkaya H , Meacci F, Niemann S, Hillemann D, Rüsch-Gerdes S; LONG DRUG Study Group, Barer MR, Andrew
PW, Oggioni MR. Evaluation of molecular-Beacon, TaqMan, and fluorescence resonance energy transfer probes for
detection of antibiotic resistance-conferring single nucleotide polymorphisms in mixed Mycobacterium
tuberculosis DNA extracts. J Clin Microbiol. 2006 Oct;44(10):3826-9. PubMed PMID: 17021120; PubMed Central
PMCID: PMC1594805.
17: Yesilkaya H , Soma-Haddrick S, Crennell SJ, Andrew PW. Identification of amino acids essential for catalytic
activity of pneumococcal neuraminidase A. Res Microbiol. 2006 Jul-Aug;157(6):569-74. Epub 2006 Feb 13. PubMed
PMID: 16844348.
18: Manco S, Hernon F, Yesilkaya H , Paton JC, Andrew PW, Kadioglu A. Pneumococcal neuraminidases A and B
both have essential roles during infection of the respiratory tract and sepsis. Infect Immun. 2006 Jul;74(7):401420. PubMed PMID: 16790774; PubMed Central PMCID: PMC1489734.
19: Kenna DT, Yesilkaya H , Forbes KJ, Barcus VA, Vandamme P, Govan JR. Distribution and genomic location of
active insertion sequences in the Burkholderia cepacia complex. J Med Microbiol. 2006 Jan;55(Pt 1):1-10. PubMed
PMID: 16388024.
20: Yesilkaya H , Forbes KJ, Shafi J, Smith R, Dale JW, Rajakumar K, Barer MR, Andrew PW. The genetic portrait of
an outbreak strain. Tuberculosis (Edinb). 2006 Sep;86(5):357-62. Epub 2005 Dec 19. PubMed PMID: 16360339.
21: Yesilkaya H , Dale JW, Strachan NJ, Forbes KJ. Natural transposon mutagenesis of clinical isolates of
Mycobacterium tuberculosis: how many genes does a pathogen need? J Bacteriol. 2005 Oct;187(19):6726-32.
PubMed PMID: 16166535; PubMed Central PMCID: PMC1251597.
22: Thomson LM, Traore H, Yesilkaya H , Doig C, Steingrimsdottir H, Garcia L, Forbes KJ. An extremely rapid and
simple DNA-release method for detection of M. tuberculosis from clinical specimens. J Microbiol Methods. 2005
Oct;63(1):95-8. PubMed PMID: 15893828.
23: Yesilkaya H , Barer MR, Andrew PW. Antibiotic resistance may affect alkali decontamination of specimens
containing mycobacteria. Diagn Microbiol Infect Dis. 2004 Oct;50(2):153-5. PubMed PMID: 15474327.
24: Yesilkaya H , Thomson A, Doig C, Watt B, Dale JW, Forbes KJ. Locating transposable element polymorphisms in
bacterial genomes. J Microbiol Methods. 2003 Jun;53(3):355-63. PubMed PMID: 12689713.
25: Dale JW, Al-Ghusein H, Al-Hashmi S, Butcher P, Dickens AL, Drobniewski F, Forbes KJ, Gillespie SH, Lamprecht
D, McHugh TD, Pitman R, Rastogi N, Smith AT, Sola C, Yesilkaya H . Evolutionary relationships among strains of
Mycobacterium tuberculosis with few copies of IS6110. J Bacteriol. 2003 Apr;185(8):2555-62. PubMed PMID:
12670980; PubMed Central PMCID: PMC152614.
26: Hirst RA, Yesilkaya H , Clitheroe E, Rutman A, Dufty N, Mitchell TJ, O'Callaghan C, Andrew PW. Sensitivities of
human monocytes and epithelial cells to pneumolysin are different. Infect Immun. 2002 Feb;70(2):1017-22.
PubMed PMID: 11796644; PubMed Central PMCID: PMC127723.
27: Yesilkaya H , Kadioglu A, Gingles N, Alexander JE, Mitchell TJ, Andrew PW. Role of manganese-containing
superoxide dismutase in oxidative stress and virulence of Streptococcus pneumoniae. Infect Immun. 2000
May;68(5):2819-26. PubMed PMID: 10768978; PubMed Central PMCID: PMC97493.