Indicative Module Descriptor: This module is designed to provide up to date information on stem cell biology and gene therapy with an emphasis on current and developing clinical strategies. Indicative Learning Outcomes: On successful completion of this module, students should be able to: 1. compare and contrast the properties of different stem cell populations. 2. describe the mechanisms involved in controlling of stem cell renewal and differentiation. 3. discuss the role of stem cells in degenerative disease and cancer. 4. describe the relative advantages and disadvantages of viral and non viral gene delivery strategies. 4. describe the principles underpinning stem cell and gene therapies with particular emphasis on current clinical strategies. Faculty 1. Developmental Biology 2. Embryonic Stem Cells 3. Hematopoietic Stem Cells 4. Adult Stem Cells including MSCs 5. Neural Stem Cells and iPS cells 6. Cancer Stem Cells 7. Chromosome Biology of Stem Cells 8. Genetic Modification of Stem Cells 9. Stem Cells and Medical Devices 10. Clinical Application of Stem Cells I (Disease Models) 11. Clinical Application of Stem Cells II (Manufacture) Uri Frank Linda Howard Rod Ceredig Mary Murphy Sanbing Chen Roisin Dwyer Kieran Morrison Thomas Ritter Faisal Sherif Tim O’Brien Frank Barry