Major Topics Assessed on the Biology Honors Final Exam This review sheet provides you with the concepts, vocabulary and techniques covered since September. Please use this as a reference to make your study guide. Scientific Inquiry (Chapter 1) - Themes in the study of biology and common features of all living things - Development of hypotheses - Design of experiments (controlled experiments) and evaluation of experimental design - Interpretation of graphs and figures - Drawing conclusions based on evidence Basic Chemistry (Chapter 2) Diagrams to Study: - Interpretation and use of periodic table - Element vs. compound 1. Compound Light Microscope - Atom vs. ion vs. isotope vs. isomer 2. Mitosis - Electron arrangement determines chemical properties 3. Meiosis - Bonding: ionic, covalent, and hydrogen 4. DNA - Polar and non-polar molecules 5. Transcription/Translation - Molecular formula and structural formula 6. Interpreting Gels - Chemistry of water and it’s life supporting properties 7. Food Webs - pH: acids, bases, and pH scale 8. Karyotype - Chemical Reactions (Chapter 5) 9. Pedigree o writing, balancing, and interpreting chemical equations 10. Chromosome structure o endergonic and exergonic reactions 11. Lac operon Biochemistry (Chapter 3) 12. Light Reactions/Calvin cycle - Carbon, functional groups, and organic compounds 13. Glycolysis/Kreb’s/ETC - Polymerization and dehydration 14. Virus - Hydrolysis 15. Eukaryotic cell - Structure, types, and function of carbohydrates 16. Prokaryotic cell - Structure, types, and function of proteins *** - Structure, types, and function of lipids - Structure, types, and function of nucleic acids - Be capable of drawing structural formulas and interpreting them Film: Lorenzo’s Oil - What disease did Lorenzo have? How did he inherit it? (Be specific) - What is the relationship between the mutation Lorenzo inherited and the disease? Microscope (Chapter 4) - parts and proper use - light vs. SEM vs. TEM - FOV and measuring with a microscope - converting between millimeters and micrometers Cells - Cell Theory (Chapter 4) - Prokaryote vs. Eukaryote (Chapter 4) - Archaebacteria vs. Eubacteria (Chapter 16) - Viruses- structure and infection cycle; DNA vs. RNA viruses (Chapter 10) Eukaryotic Cell Structure & Function : (Chapter 4) - identification of cell parts - explanation of the function of each part - explain how a part’s structure fits its function - describe a process that several cell parts work together to accomplish Cell Membrane and Cell Transport (Chapter 5) - Membrane structure and function - Active and Passive Transport Energy and the Cell (Chapter 5) - Laws that govern energy transformation - ATP-ADP cycle - How enzymes function Cycling of Matter and Flow of Energy in the Biosphere (Chapter 6, 7, and 37) - Oxygen and Carbon cycles - Role of photosynthesis and cell respiration in the cycles and moderation of global warming - Photosynthesis - equation, reactants, products, requirements, light reactions, and Calvin cycle - Cell Respiration- equation, reactants, products, requirements, glycolysis, Krebs (citric acid) cycle, and Electron Transport Chain (oxidative phosphorylation) - Food chains, food webs, 10% rule, and ecological pyramids Cell Reproduction (Chapter 8) - Prokaryotes rely on binary fission - Cell cycle - Eukaryotes rely on mitosis & cytokinesis - Cancer (Chapter 8 & 11) - Meiosis: stages, goal of Meiosis I, goal of Meiosis II, and events such as tetrad formation and crossing over - Chromosomal mutations, karyotypes, and genetic disorders DNA (Chapter 10 & 11) - Structure and function - Replication - Gene Expression o DNA RNA Protein (Central Dogma) o Protein synthesis o Gene mutations o Regulating Gene Expression in Prokaryotes (operons) o Regulating Gene Expression in Eukaryotes (master control genes, switches, etc) Genetics (Chapter 9) - Mendel’s Laws of Heredity - one factor crosses - two factor crosses - Genetic recombination (draw the connection between events of meiosis that explain Mendel’s observations) - Interpreting a pedigree - Complex Patterns of Inheritance: o Incomplete dominance o Codominance o Sex-Linked Inheritance o Multiple Alleles o Polygenic Traits - Other factors that affect expression of traits (environment and epigenetics) Evolution (Chapter 13, 14, & 15) - Darwin, descent with modification, and natural selection - Evidence for evolution - Explain how genetic variation makes evolution possible - Use of Hardy-Weinberg equation to assess if a population is evolving - Mechanisms of microevolution- natural selection, genetic drift, and gene flow - Macroevolution and speciation (adaptive radiation) - Divergent vs. convergent evolution - Gradualism vs. punctuated equilibrium - Phylogeny Biotechnology (Chapter 12) - Gene Cloning - GMO’s - DNA Profiling/ Gel electrophoresis - Genomics