Modeling Passive Diffusion of Oxygen Practice Directions: 1. Set up your model by showing oxygen molecules as shown on the left on either side of your cell membrane. 2. Show how molecules move by passive diffusion using your model pieces. 3. Move the oxygen molecules until they reach equilibrium. Assessment Questions for your model: Answer the questions below and be prepared to answer these questions for your teacher. 1. Explain what causes oxygen molecules to move across the cell membrane. 2. What is passive diffusion? 3. What are some molecules that can move by passive diffusion? Modeling Passive Diffusion (Osmosis) of Water Practice Directions: 1. Create a semi-permeable cell membrane from yarn. It will allow water to pass, but not sodium. 2. Set up your model with sodium and water molecules as shown on the left on either side of the cell membrane. 3. Demonstrate osmosis by moving the water molecules in your model. 4. Practice moving water molecules across the cell membrane until they reach equilibrium. Assessment Questions for your model: Answer the questions below and be prepared to answer these questions for your teacher. 1. Explain why water molecules move across the membrane. 2. After the diffusion of water, how much water is inside the cell compared to outside the cell? Why? Modeling Facilitated Diffusion of Glucose Practice Directions: 1. Set up your model as shown on the left. Place a protein channel in the cell membrane and glucose molecules outside the cell membrane. 2. Demonstrate facilitated diffusion by moving glucose molecules through the protein channel. 3. Practice moving glucose molecules across the cell membrane until equilibrium is reached. Assessment Questions for your model: Answer the questions below and be prepared to answer these questions for your teacher. 1. Why do glucose molecules require a protein channel? 2. How is the transport of glucose similar to passive diffusion? How is it different? 3. Why is the diffusion of glucose “facilitated” Modeling Active Transport of Sodium Practice Directions: 1. Set up your model as shown on the left, with sodium, water, and ATP on either side of the cell membrane. 2. Demonstrate active transport by moving the sodium molecules across the protein channel in your model. Recall, in active transport molecules require energy in the form of ATP to cross the protein channel. 3. Place an ATP molecule on the protein channel to model energy in this process. 4. You can move three sodium molecules through the protein channel with one ATP. Note: The energy provided by ATP, not concentration gradients, moves molecules in active transport. Molecules do not need to reach equilibrium. Assessment Questions for your model: Answer the questions below and be prepared to answer these questions for your teacher. 1. Describe and explain how sodium molecules move across the cell membrane. 2. What is necessary for a molecule to move with active transport? 3. Why do molecules like sodium enter the cell by active transport and not by passive diffusion. Cell A: Students should set up the cell as shown above (low in oxygen and glucose). Students should use the concepts from practice to describe and model how molecules move by active transport, osmosis, facilitated diffusion and/or passive diffusion. Cell B: Students should set up the cell as shown above (low in oxygen, water, and sodium). Students should use the concepts from practice to describe and model how molecules move by active transport, osmosis, facilitated diffusion and/or passive diffusion. Cell C: Students should set up the cell as shown above (low in oxygen, water, glucose, and sodium). Students should use the concepts from practice to describe and model how molecules move by active transport, osmosis, facilitated diffusion and/or passive diffusion.