Supplementary Abstract References (SAR)
SAR-1| Blazsek, I. & Péault, B. Ontogenesis of the hematon, a morphogenetic stromal unit that
supports primary hematopoiesis in mouse bone marrow. Exp. Hematol. 28, p116, abstr.268 oral (29th
Annual Meeting, ISEH, Tampa, Florida, USA, 2000).
SAR-2| Blazsek, I., Chagraoui, J., Oberlin, E., Uzan, G. & Péault, B. Fate map of stromal cell-associated
hematopoietic and hepatic stem cells in the mouse liver primordium. Exp. Hematol. 29, p107,
abstr.420 oral (30th Annual Meeting, ISEH, Tokyo, Japan, 2001).
SAR-3| Blazsek, I., Chagraoui, J., Oberlin, E., Uzan, G. & Péault, B. Ontogenic fate of mesenchymal cell
associated hepatic and hematopoietic stem cells in the mouse liver.[or Niches save the Queen]. Exp.
Hematol. 30, p127, abstr.361 poster (31st Annual Meeting, ISEH, Montreal, Canada, 2002).
SAR-4| Blazsek, I., Oberlin, E., & Péault, B. Organotypic specification of stem-cell-nests during
organogenesis. Exp. Hematol. 31, p76, abstr. 50 oral (32th Annual Meeting, ISEH, Paris, France, 2003).
SAR-5| Blazsek, I., Oberlin, E., Souyri, M. and Péault, B. The osteo-hematon: modeling the
ontogenic development of stem-cell niches into discrete organotypic proliferative units.
Blood 104, p192a, abstr. 667 oral (46th Annual Meeting, Am. Soc. Hematol, San Diego, 2004)
SAR-6| Blazsek I. Purification and spatial-temporal analysis of hepatic and hematopoietic stem cells
niches that develop into structural proliferative units in the mammalian liver. 1st International NIH
Cellular Niches Workshop , oral (May 16-17, 2005, Bethesda, 2005).
SAR-7| Blazsek, IJ., Oberlin, E., Souyri, M., Péault, B. The osteo-hematon: ontogenic development
and biology of stem cell niches. Exp. Hematol. 33, p21, abstr.323, poster (34th Annual Meeting ISEH,
Glasgow, Scotland 2005).
SAR-8| Blazsek, I.J.G., Pierre-Louis, O., Clay, D., Leclerc, Ph., Blazsek, J., Dobó-Nagy, C., Uzan, G. & Le
Bousse-Kerdiles, M.C. Stem cell niches reside in physiological tissue units in vertebrate blood-forming
tissues. Exp. Hematol. 37, p21, abstr.004 oral (38th Annual Meeting ISEH, Athens, Greece, 2009).
SAR-9| Blazsek, I.J.G., Clay, D., Pierre-Louis, O., Leclerc, Ph., Delmas-Marselet, B., Machover, D.
Uzsan, G, and Le Bousse-Kerdiles, C. Stem cell niches are isolatable from human bone marrow
entities. Strange morphogen attractors with robust, tissue-specific, self-organizing power.
Exp. Hematol. ,38, p206, abstr.46 poster (39th Annual Meeting ISEH, Melbourn, Australia 2010).
SAR-10| Blazsek, I., Clay, D., Leclerc, Ph., Jodon de Villeroché, V., Candelier, J.J., Delmas-Marselet, B.,
Mathé, G., Machover, D., Uzan, G. & Le Bousse-Kerdiles, M.C. The Osteo-Hematon: Definition,
characterization and clinical applications of physiological tissue units involving stem-cell-niches in
human bone marrow. 5th CMBF Congress, oral, Beijing, China, 2011.
Associated Publications
1. Blazsek, I., Misset, J.L., Comisso, M. & Mathé, G. Hematon: a multicellular functional unit in
primary hematopoiesis. Biomed. Pharmacother. 42, 661-670 (1988).
2. Blazsek, I. et al. Hematon, a multicellular functional unit in normal human bone marrow:
structural organization, hemopoietic activity, and its relationship to myelodysplasia and
myeloid leukemias. Exp. Hematol. 18, 259-265 (1990).
3. Blazsek, I. et al. The hematon, a morphogenetic functional complex in mammalian bone
marrow, involves erythroblastic islands and granulocytic cobblestones. Exp. Hematol. 23,
309-319 (1995).
4. Blazsek, I., Chagraoui, J. & Péault, B. Ontogenic emergence of the hematon, a morphogenetic
stromal unit that supports multipotential hematopoietic progenitors in mouse bone
marrow. Blood 96, 3763-3771 (2000).
5. Blazsek, I. et al. Large scale recovery and characterization of stromal cell-associated primitive
haemopoietic progenitor cells from filter-retained human bone marrow. Bone Marrow
Transplant. 23, 647–657 (1999).
6. Blazsek, I. et al. Bone marrow stromal cell defects and 1α,25-dihydroxyvitamin D3 deficiency
underlying human myeloid leukemias. Cancer Detect. Prevent. 20, 31-42 (1996).
7. Vicente, D. et al. Progenitor cells trapped in marrow filters can reduce GvHD and transplant
mortality. Bone Marrow Transplant. 38, 111-117 (2006).