Biology Final Exam Study Guide Spring 2015 Chapter 12: DNA Covers Sections 12.1, 12.2, and 12.3 (p. 342-353) Vocabulary Nucleic acid Nucleotide Phosphate group Deoxyribose Nitrogenous base Adenine Cytosine Guanine Thymine Double helix Concepts 1. What are the three roles of DNA? 2. List the three parts of a nucleotide. 3. List the four nucleotides that make up DNA. 4. Explain Chargaff’s Rule (base-pairing rules). 5. Name the two parts of a nucleotide that form DNA’s backbone. 6. List and describe the steps of DNA replication. 7. Describe the two jobs that DNA polymerase has in DNA replication. Base pairing Complementary bases DNA replication Replication fork DNA polymerase Chapter 13: RNA and Protein Synthesis Covers Sections 13.1, 13.2 and 13.3 (p. 362-376) Vocabulary RNA Uracil Messenger RNA Transfer RNA Ribosomal RNA RNA synthesis Transcription RNA polymerase Promoter Polypeptide Genetic code Codon Protein synthesis Translation Anticodon Mutations Point mutation Substitution Insertion Deletion Frameshift mutation Chromosomal mutation Mutagen Concepts 1. Know the difference between a DNA nucleotide and an RNA nucleotide (DNA has deoxyribose; RNA has ribose in its nucleotides). 2. Compare and contrast DNA and RNA molecules, their functions, and where they are located in the cell. 3. Know base-pairing rules between DNA and RNA, and between RNA and RNA molecules. 4. List the steps involved in transcription (RNA synthesis). 5. 6. 7. 8. 9. What is the job of RNA polymerase in transcription? What does the promoter tell RNA polymerase to do? List the steps involved in translation (protein synthesis). Know the differences between transcription and translation Know how to use an mRNA codon chart to figure out the order of amino acids in a polypeptide chain made during translation from an mRNA molecule. 10. Explain how codons and anticodons work with each other. 11. Know that information in cells travels in the following order: DNA → RNA → protein → trait. 12. Describe the two main categories of mutations (point and chromosomal). 13. List and describe the different types of point mutations. 14. Explain why frameshift mutations can be extremely damaging. 15. List and describe the different types of chromosomal mutations. 16. List some things that can cause mutations. Chapters 16, 17 & 19: Evolution Covers: Sections 16.1, 16.2, 16.3, and 16.4 (p. 454-471) Sections 17.1, 17.2, and 17.3 (p. 483, 487-490, 494-497) Section 19.2 (p. 546-551) Vocabulary Evolution Artificial selection Natural selection Adaptation Fitness Biogeography Homologous structures Analogous structures Vestigial structures Gene pool Allele frequency Directional selection Stabilizing selection Disruptive selection Genetic drift Bottleneck effect Founder effect Species Speciation Reproductive isolation Behavioral isolation Geographic isolation Temporal isolation Macroevolution Gradualism Punctuated equilibrium Concepts 1. List and describe the three key observations Darwin made as a result of the HMS Beagle voyage. 2. List and describe the three factors that must occur in natural selection. 3. Be able to describe how natural selection would work in nature. 4. Explain how artificial selection is different than natural selection. 5. Explain the meaning of Darwin’s statement “descent with modification”. 6. Describe and give examples of the four major categories of evidence for evolution: a. Biogeography b. Fossils and the age of the earth c. Comparing anatomy and embryology d. Genetics and molecular biology 7. Explain how homologous structures are different from analogous structures. 8. Explain why vestigial structures can be important in showing evolution. 9. Define evolution in genetic terms (see p. 483). 10. Describe how a gene pool and allele frequencies are related to each other. 11. Describe directional selection, and know what the graph that shows directional selection looks like. 12. Describe stabilizing selection, and know what the graph that shows stabilizing selection looks like. 13. Describe disruptive selection, and know what the graph that shows disruptive selection looks like. 14. Explain why genetic drift is different than natural selection. 15. What causes a genetic bottleneck? What is the result of this genetic bottleneck? 16. What causes the founder effect? What is the result of this founding population? 17. Explain why the bottleneck effect and the founder effect are both examples of genetic drift. 18. List and describe the three types of reproductive isolation. Give an example of each one. 19. Why does reproductive isolation lead to speciation? 20. Explain how speciation occurs in Darwin’s finches (see p. 496 in your book). 21. Compare and contrast gradualism with punctuated equilibrium. Chapter 6: Humans in the Biosphere Covers: Section 6.3 and 6.4 (p. 166-179) Vocabulary Biodiversity Genetic diversity Ecosystem diversity Habitat fragmentation Species diversity Introduced species Ecological hot spot Climate change Global warming Concepts 1. Compare the three levels of biodiversity. 2. Give examples of the economic value that biodiversity provides to humans. 3. Give examples of threats to biodiversity. 4. Give examples of conservation of biodiversity. 5. Describe the evidence that scientists use to show that the climate is changing. Chapters 30 & 33: Anatomy and Physiology Includes: Chapter 30 Sections 30.1, 30.4 Chapter 33 Sections 33.1, 33.3 Vocabulary Cell Tissue Epithelial tissue Connective tissue Nervous tissue Muscle tissue Organ Organ system Homeostasis Feedback inhibition Excretion Skin Lungs Liver Kidneys Ureters Urinary bladder Urethra Heart Myocardium Atrium Ventricle Valves Pulmonary circulation Systemic circulation Sinoatrial (SA) node/pacemaker Atrioventricular (AV) node Arteries Capillaries Veins Blood Plasma Red blood cells (erythrocytes) White blood cells (leukocytes) Platelets Blood pressure Systolic pressure Diastolic pressure Cholesterol Atherosclerosis Heart attack Stroke Nose Pharynx Trachea Larynx Bronchi Bronchioles Alveoli Hemoglobin Diaphragm Inhalation Exhalation Chronic bronchitis Emphysema Lung cancer Concepts 1. List and describe the four tissue types. 2. Explain feedback inhibition (negative feedback loop), and give an example. 3. Either list the steps or diagram the flow of blood through the heart. Know all the relevant chambers, valves, arteries, and veins in order. 4. Describe the process of the heartbeat. 5. Describe the three types of blood vessels. 6. Know what blood plasma contains. 7. Know the three types of blood cells and their functions. 8. Describe what causes blood pressure, and indicate a “good” blood pressure reading. 9. Give some examples of circulatory disease and their causes. 10. Trace the pathway that air takes in and out of the body during breathing, and indicate how the diaphragm and rib muscles are involved. 11. Explain what happens during gas exchange in the lungs. 12. Give some examples of respiratory disease, and their causes.