DNA to Protein Notes DNA = _______________________________________________________________________ RNA = ________________________________________________________________________ Where does DNA “live”? ______________________________________ Why is DNA so Important? 1. DNA is a nucleic acid that contains the __________________________________________________ used in the development and functioning of all living things and some viruses. 2. DNA is like ________________________, _______________________, or a ________ for making proteins 3. DNA’s codes are converted/changed into messages (_____________) for______________________ to read and then make proteins. 4. ______________________________________________________________________________________ What are the parts of DNA? The “Backbone” Has 2 Parts: D = _______________________________ P = ______________________ The “Rungs” include the nitrogen bases A = ________________________________ T = ________________________________ C =_________________________________ G =_________________________________ How to remember Nitrogen Bonds: A bonds with T Think: C bonds with G Think: Nucleotides are the building blocks: 1 ______________________ 1 _____________________ 1 __________________________ What are the complementary nitrogen bases in this sequence of DNA? ATT CGT TAT CGT CTG AAA ACG Why is mRNA Important? 1. DNA is too big and CAN’T leave the ___________________…it must send _________________________ 2. _____________________________ is created by DNA in the nucleus 3. mRNA contains the messages from the DNA and are sent to _________________________________ for them to read the instructions for making proteins What are the parts of RNA? Notice that RNA has ___________ Strand! RNA is Made of: 1. Ribose (_______________) 2. Phosphate (_________________________) 3. Nitrogen Bases (____, ____, _____, _____) U stands for _____________________….a different nitrogen base A bonds with U NO THYMINE in RNA!! C bonds with G How does DNA tell the cell to make a specific kind of protein? There are 2 major steps in this process First: ______________________________________ Second: ______________________________________ Transcription : Process in which ____________ is synthesized from the _________________________________. HINT: Transcription is when mRNA is made from DNA. * mRNA: (_________________________) holds the ___________________ for making proteins How does Transcription work? * QUESTION…have you been to court? * There is a person typing what is said and is creating a “court transcript”…which is really a code…shortened version…and later the transcript is translated into all the words that were said for a record. SHORTENED CODE = mRNA Lets Practice: Create a RNA strand using this sequence of DNA? ATT CGT TAT CGT CTG AAA ACG Now What?...Translation! Translation: Process in which mRNA attaches to the ribosome and a protein is ____________________________. Words to know: 1. Codon: 3 base code in ________ or________ EX: ACG ATA CGG CTT 2. Amino Acid: Compounds joined by ____________________________ to build proteins There are ___________ different amino acids. Different combination of amino acids make different kinds of proteins. 3. Ribosome: “_______________” mRNA recipes so it can synthesize/make proteins 4. tRNA: (__________________________) Type of RNA that transports amino acids to the ribosome 5. Anticodon: ________________________________________ that can pair that corresponds with the codons on the mRNA Translating mRNA codes into amino acids to create polypeptide chains (______________________________) #1. AUG GCA UCC UGA ________________________, _________________________, _________________________, _______________ #2. AUG CCC GGU UAG ________________________, _________________________, _________________________, _______________ #3. AUG AAG GUG UGA ________________________, _________________________, _________________________, _______________ What is the amino acid for the following codons? AAU GUG UGG How can knowing amino acid sequences in organisms help biologists? We can use the____________________________to see how organisms are ____________________! Which of the following two organisms are MOST closely related? Fish Sequence: Methionine, Isoleucine, Arginine, Isoleucine, Glycine, Serine Lizard Sequence: Methionine, Isoleucine, Serine, Glycine, Alanine, Tyrosine Frog Sequence: Methionine, Isoleucine, Serine, Leuicine, Lysine, Lysine Bird Sequence: Methionine, Isoleucine, Serine, Glycine, Alanine, Valine