Chromosome Dynamics Late Summer Meeting Vienna, September 9-12, 2012 IMP Lecture Hall Sunday, September 9, 2012 from 02:30 champagne reception 03:00-04:00 pm Welcome The basic structure of chromosomes (Chair: N. Kleckner) 4:00-04:45 pm 04:45-05:20 pm Nancy Kleckner (keynote) “Loops and Tethers Along and Between Chromosomes: Important Roles and Important Constraints for Meiotic and Mitotic Chromosomes and for E. coli” Jan Michael Peters “Wapl controls higher-order chromatin structure in interphase chromosomes” Coffee break 05:35-06:10 pm 06:10 -06:45 pm 06:45-07:20 pm Barbara J. Meyer “Establishing and Releasing Chromosome Cohesion During Gamete Production” Denise Zickler “Contribution of filamentous fungi to the understanding of meiosis” Iva Tolic “Meiotic chromosome oscillations: What are they good for?” 07:30 pm Dinner at Cafeteria ____________________________________________________________ Monday, September 10, 2012 DSBs, repair and regulations I (Chair: Alain Nicolas) 09:00-09:35 am 09:35-10:10 am 10:10-10:45 am Alain Nicolas “Role of G-quadruplexes in genome instability” Peter Schlögelhofer “DSBs in wild type and mutant yeast” Gerry Smith “Meiotic DSB Hotspots: Protein Determinants, DSB Interference, and Hotspot Clustering” Coffee break 11:15-11:50 am Vincent Géli “Interaction between Mer2 and the COMPASS subunit Spp1 links meiotic DSB sites to chromosome axis” 11:50-12:25 am Timothy Humphrey “A chromatin switch regulating DNA double-strand break repair pathway choice'” Attila Toth “Surveillance mechanisms of the meiotic prophase in mammals” 12:25-01:00 pm 01:00-02:00 pm Lunch at Cafeteria DSBs, repair and regulations II (Chair: Michael Lichten) 02:00-02:35 pm 02:35-03:10 pm 03:10-03:55 pm 03:55-04:30 pm Enrique Martinez-Perez “Finding the correct pairing partner during meiosis: events inside and outside the nucleus” Jordi Torres-Rossel "Regulation of SMC complexes by SUMO, and vice versa." Andrea Pichler "Role of Ubc9 sumoylation in meiotic chromosome synapsis in Saccharomyces cerevisiae" Nancy Hollingsworth “Roles of the Rad51 and Dmc1 recombinases in budding yeast meiosis” Coffee break 04:45-05:20 pm 05:20-05:55 pm 05:55-06:30 pm Anne Villeneuve “Regulating DSB and crossover formation during C. elegans meiosis” Michael Lichten "Control of meiotic recombination outcome: Sgs1 helicase acts as a chaperone for meiotic recombination intermediates" Franz Klein "The Smc5/6 complex acts in the non-ZMM pathway of meiotic recombination" Social program: Dinner at Meierei im Stadtpark ____________________________________________________________ Tuesday, September 11, 2012 Cell cycle & segregation (Chair: Wolfgang Zachariae) 09:00-9:35am 09:35-10:10 am 10:10-10:45 am Wolfgang Zachariae "How Meiotic Cells Switch from Prophase into M-phase" Albert Sickman “Dynamics of protein degradation” Daniel Gerlich "Aurora B-counteracting phosphatases in the regulation of chromosome segregation" Coffee break 11:00-11:35 am 11:35-12:10 pm 12:10-12:45 pm Mary Herbert “Plk1 is required for stepwise removal of cohesion during meiosis in mammalian oocytes” Kikue Tachibana-Konwalski "The spindle assembly checkpoint of meiosis I oocytes depends on a kinetochore structure determined by cohesion" Mark Petronczki "Delivery of the cytokinetic signal to the cell envelope" 01:00-02:00 pm Lunch at Cafeteria Social program: 02:00-03:00 pm 150th birthday Klimt: guided tour Belvedere 05:00-06:00 pm guided tour Secession 06:00 pm Dinner “Zu den 3 Buchteln” ____________________________________________________________ Wednesday, September 12, 2012 Kinetochore & Segregation (Chair: Tomo Tanaka) 09:00-9:35 am 09:35-10:10 am 10:10-10:45 am Tomo Tanaka “A common kinetochore-associated mechanism governs replication timing and sister chromatid cohesion at yeast peri-centromeres” Stefan Westermann "Molecular architecture of the budding yeast kinetochore" Kevin Corbett “Structure and mechanism of the S. cerevisiae monopolin complex" Coffee break 11:15-11:50 am 11:50-12:25 pm 12:25-01:00 pm Franz Herzog "Structural probing of a protein phosphatase 2A network by chemical cross-linking and mass spectrometry” Juro Gregan “The role of casein kinase 1 in fission yeast meiosis” Marie-Hélene Verlhac “Cortical stiffness prevents spindle positioning in mouse oocytes” Good bye lunch at Lusthaus