CLUSTER Health Science Education CONCENTRATION Biotechnology Research and Development WEVIS CODE HE0780 National Consortium for Health Science Education Health Care Standards and Accountability Criteria http://www.healthscienceconsortium.org/docs/biotech_pathway.pdf Sample of reported job titles upon completion of the Biotechnology Research and Development cluster: Certified Phlebotomy Technician, Laboratory Aide Sample of reported job titles upon completion of additional education: Biochemist, Bioinformatics Scientist, Biomedical Chemist, Biomedical Manufacturing Technician, Biostatistician, Cancer Registrar, Cell Biologist, Clinical Data Management Specialist, Clinical Pharmacologist, Crime Scene Investigator, Diagnostic Molecular Scientist, Forensic Biologist, Forensic Chemist, Forensic Odontologist, Forensic Pathologist, Genetic Counselor, Geneticist-Lab Assistant, Lab Technician, Medical Editor/Writer, Microbiologist, Molecular Biologist, Nurse Researcher, Packaging Technician, Patent Lawyer, Pharmaceutical Sales Representative, Pharmacologist, Processing Technician, Quality Assurance Technician, Quality Control Technician, Regulatory Affairs Specialist, Research Assistant, Research Scientist, Toxicologist INDUSTRY CREDENTIALS Certified Phlebotomy Technician, CPR/AED Healthcare Provider or Professional Rescuer, First Aid, Bloodborne Pathogens Training: Preventing Disease Transmission REQUIRED COURSES (Required Sequence) Note: A minimum course completion score of 80% is required to progress to next course. WVEIS Code 0711 0715 0707 0708 Course Foundations of Health Science Advanced Principles of Health Science Biomedical Applications Biomedical Innovation ELECTIVE COURSES 0716 0721 0725 0730 0739 1060 Body Structures and Functions Medical Terminology Understanding Human Behavior Health Science Clinical Experience Nutrition and Wellness Essentials of Addiction and Prevention SKILL SETS Career Preparation Skills Safety Practices Leadership Development Patient/Client Customer Service Literacy and Numeracy Academic Foundation Communications Systems 1 Legal Responsibilities Ethics Health Maintenance Practices Technical Skills Teamwork Information Technology Applications Contributions of Biotechnology to Health and the Human Condition Introduction to Biotechnology Knowledge Areas and Techniques Laboratory Protocols and Procedures Product Design and Development Bioethics/Biomedical Research and Development Follow Regulatory Guidelines Quality Assurance and Safety Practices Demonstrate Problem Solving and Decision Making Skills Utilize and Maintain Equipment and Supplies Specific to Bio-medical Labs Phlebotomy Certification/Clinical Experience 2 Career Preparation, Safety, Leadership Development, Customer Service and Literacy and Numeracy skill sets should be integrated throughout the concentration as remaining skill sets are delivered. Skill Set Knowledge Objectives HE.1 Career Preparation Skills Students will demonstrate knowledge of career paths. goal development and achievement. attitudes and work habits that support career retention and advancement. personal qualities and abilities needed to be effective as a healthcare provider. Performance Objectives HE.2 HE.3 HE.4 HE.5 HE.6 HE.7 HE.8 HE.9 HE.10 Skill Set Knowledge Objectives HE.11 Performance Objectives HE.12 HE.13 HE.14 Skill Set Knowledge Objectives HE.15 Performance Objectives HE.16 HE.17 HE.18 HE.19 HE.20 communication in varied contexts. Students will relate skills and abilities to possible career pathways. explain methods of goal development. discuss methods of time management and task coordination. practice professionalism in punctuality, appropriate dress, task completion, etc. investigate methods of supervision such as giving and receiving feedback and instruction. develop and present a statement of their personal work ethic beliefs. prepare an application, cover letter, resume and thank you letter. create a personal portfolio for use when applying for employment. practice simulated job interviews. Safety Practices Students will demonstrate knowledge of infection control. controlling the growth and spread of microorganisms. Students will explain principles of infection control. perform hand washing according to Centers for Disease Control regulations. don and remove non-sterile gloves. Leadership Development Students will demonstrate knowledge of public speaking. parliamentary law. leadership concepts. characteristics of effective teams and organizations. Students will develop and deliver speeches. participate in meetings using parliamentary procedure. attend leadership conferences and training (local, state and/or national). volunteer in community service opportunities. participate in career development events. 3 Skill Set Knowledge Objectives HE.21 Performance Objectives Patient/Client Customer Service Students will demonstrate knowledge of customer service. patient/client satisfaction. patient/client needs assessment. quality for services. Students will HE.22 HE.23 HE.24 HE.25 HE.26 HE.27 HE.28 HE.29 HE.30 HE.31 HE.32 HE.33 Skill Set Knowledge objectives HE.34 Performance Objectives demonstrate respectful and empathetic treatment of all patients/clients. hear and work to resolve complaints from patients/clients or the public. check completed work for spelling, punctuation and format. greet visitors or callers and handle their inquiries or direct them to the appropriate persons according to their needs. answer inquiries pertaining to patient care policies and services and work to resolve patient/client complaints. measure and assess patient/client and employee satisfaction. confer with patients/clients by telephone or in person to provide information about health care or services, take orders from superiors, obtain details of complaints and forward to instructor/supervisor. keep records of patient/client interactions, recording details of inquiries, complaints or comments, as well as actions taken per health care institution guidelines. check to ensure that appropriate changes were made to resolve patient/client problems. describe points of patient safety and respond to questions. investigate and work to resolve complaints regarding food quality, service or patient care within your scope of practice. identify the characteristics of each health care industry’s target market. Literacy and Numeracy Students will demonstrate knowledge of literacy and numeracy skills required to solve complex. real-world problems associated with their career/technical content area. improve their thinking and reasoning skills. Students will HE.35 HE.36 HE.37 HE.38 utilize a variety of technical sources (e.g., Internet, manuals, journals, directions, reports, etc.) to complete career/technical assignments and projects. demonstrate writing skills required to complete career/technical assignments and projects. demonstrate accuracy in calculating and measuring graphical work required to complete career/technical assignments and projects. analyze tables, charts, graphs and multiple data sources to complete career/technical assignments and projects. 4 Foundations of Health Science WVEIS 0711 * Foundations of Health Science (0711) is a prerequisite for Advanced Principles of Health Science (0715). These two courses provide the introductory core for all Health Science Concentrations. *Admission to Advanced Principles of Health Science requires a minimum course completion score of 80% in Foundations of Health Science. Skill Set Knowledge Objectives 0711.1 Performance Objectives 0711.2 0711.3 0711.4 0711.5 0711.6 0711.7 0711.8 Skill Set Knowledge Objectives 0711.9 Performance Objectives 0711.10 0711.11 0711.12 0711.13 0711.14 0711.15 Skill Set Knowledge Objectives 0711.16 Performance Objectives Academic Foundation Students will demonstrate knowledge of human growth and development. nutrition. Students will explain the four main areas of growth and development in each of the seven life stages. examine Maslow’s Hierarchy of Needs theory. discuss key issues surrounding end-of-life care. create scenarios to analyze the five stages of grief. identify the six essential nutrients. examine the basic food groups. compare therapeutic diets. Communications Students will demonstrate knowledge of medical terminology. concepts of effective communication skills. written communication skills. Students will use roots, prefixes and suffixes to communicate information. interpret verbal and nonverbal communication. recognize barriers to communication. recognize the elements of communication using a sender-receiver model. apply speaking and active listening skills. recognize elements of written and electronic communication (spelling, grammar and formatting). Systems Students will demonstrate knowledge of health care delivery systems. Students will 0711.17 discuss the health care delivery system (public, private, government and nonprofit). 0711.18 describe the responsibilities of consumers within the health care system. 5 Skill Set Knowledge Objectives 0711.19 Performance Objectives Teamwork Students will demonstrate knowledge of health care teams. team member participation. Students will recognize characteristics of effective teams. 0711.20 recognize methods for building positive team relationships. 0711.21 0711.22 analyze attributes and attitudes of an effective leader. Skill Set Health Maintenance Practices Knowledge Objectives Students will demonstrate knowledge of 0711.23 healthy behaviors. Performance Objectives Students will apply behaviors that promote health and wellness. describe strategies for the prevention of diseases including health screenings and examinations. 0711.26 discuss complementary (alternative) health practices as they relate to wellness and disease prevention. Skill Set Technical Skills Knowledge Objectives Students will demonstrate knowledge of 0711.24 0711.25 0711.27 medical emergency response procedures. Performance Objectives Students will apply skills to obtain training and/or certification in Health Care Provider or Professional Rescuer CPR, AED and FBAO. apply skills to obtain training and/or certification in First Aid. 0711.29 Skill Set Information Technology Applications Knowledge Objectives Students will demonstrate knowledge of 0711.28 0711.30 information technology. Performance Objectives Students will 0711.31 communicate using technology to access and distribute data and other information. 6 Advanced Principles of Health Science WVEIS 0715 * Foundations of Health Science (0711) is a prerequisite for Advanced Principles of Health Science (0715). These two courses provide the introductory core for all Health Science Concentrations. *Admission to Advanced Principles of Health Science requires a minimum course completion score of 80% in Foundations of Health Science. Skill Set Knowledge Objectives 0715.1 Performance Objectives 0715.2 0715.3 0715.4 0715.5 0715.6 0715.7 0715.8 0715.9 0715.10 Skill Set Knowledge Objectives 0715.11 Performance Objectives 0715.12 0715.13 0715.14 Skill Set Knowledge Objectives Academic Foundation Students will demonstrate knowledge of human structure and function. diseases and disorders. medical mathematics. Students will classify the basic structural and functional organization of the human body (tissue, organ and system). recognize body planes, directional terms, quadrants and cavities. analyze the basic structure and function of the human body. describe common diseases and disorders of each body system (prevention, pathology, diagnosis and treatment). recognize emerging diseases and disorders. investigate biomedical therapies as they relate to the prevention, pathology and treatment of disease. apply mathematical computations related to healthcare procedures (metric and household, conversions and measurements). analyze diagrams, charts, graphs and tables to interpret healthcare results. record time using the 24-hour clock. Communications Students will demonstrate knowledge of concepts of effective communication. medical terminology. Students will report subjective and objective information. use roots, prefixes and suffixes to communicate information. use medical abbreviations to communicate information. Systems Students will demonstrate knowledge of 0715.15 health care delivery systems. Performance Objectives Students will 0715.16 0715.17 0715.18 explain factors influencing the health care delivery system. explain the impact of emerging issues such as technology, epidemiology, bioethics and socioeconomics on healthcare delivery systems. discuss common methods of payment for healthcare. 7 Skill Set Knowledge Objectives 0715.19 Performance Objectives 0715.20 0715.21 0715.22 0715.23 0715.24 0715.25 0715.26 Skill Set Knowledge Objectives 0715.27 Performance Objectives Legal Responsibilities Students will demonstrate knowledge of legal implications. legal practices. Students will analyze legal responsibilities. apply procedures for accurate documentation and record keeping. apply for Health Insurance Portability and Accountability Act (HIPAA). describe advance directives. summarize the Patient’s Bill of Rights. discuss informed consent. explain laws governing harassment, labor and scope of practice. Ethics Students will demonstrate knowledge of ethical boundaries. ethical practice. cultural, social and ethnic diversity. Students will 0715.28 0715.29 0715.30 0715.33 differentiate between ethical and legal issues impacting healthcare. recognize ethical issues and their implications related to healthcare. apply procedures for reporting activities and behaviors that affect the health, safety and welfare of others. understand religious and cultural values as they impact healthcare. 0715.31 demonstrate respectful and empathetic treatment of ALL patients/clients 0715.32 (customer service). Skill Set Safety Practices Knowledge Objectives Students will demonstrate knowledge of infection control. personal safety. environmental safety. common safety hazards. emergency procedures and protocols. 8 Performance Objectives 0715.34 0715.35 0715.36 0715.37 0715.38 0715.39 0715.40 0715.41 0715.42 0715.43 Skill Set Knowledge Objectives 0715.44 Performance Objectives Students will explain principles of infection control. describe methods of controlling the spread and growth of microorganisms. apply personal safety procedures based on Occupational Safety and Health Administration (OSHA) and Centers for Disease Control (CDC) regulations. apply skills to obtain training and/or certification in Bloodborne Pathogens – Preventing Disease Transmission (American Red Cross). demonstrate principles of body mechanics. demonstrate safety techniques in the laboratory setting. comply with safety signs, symbols and labels. recognize types of hazardous materials. explain fire safety in a healthcare setting. apply principles of basic emergency response in natural disasters and other emergencies. Teamwork Students will demonstrate knowledge of health care teams. team member participation. Students will 0715.45 understand roles and responsibilities of team members. 0715.46 apply effective techniques for managing team conflict. Skill Set Technical Skills Knowledge Objectives Students will demonstrate knowledge of 0715.47 vital signs. Performance Objectives Students will 0715.48 Skill Set Knowledge Objectives apply procedures for measuring and recording vital signs including normal ranges. Information Technology Applications Students will demonstrate knowledge of 0715.49 information technology. Performance Objectives Students will 0715.50 0715.51 0715.52 0715.53 utilize current computer hardware and software. identify records, files and technology applications common to healthcare. enter data into computer files using reference tools to ensure accuracy. maintain security and confidentiality of electronic patient information adhering to workplace policies. 9 Biomedical Applications WVEIS HE0707 * Foundations of Health Science (0711) and Advanced Principles of Health Science (0715) provide the introductory core for all Health Science Concentrations and require a minimum course completion score of 80% in order to advance to Biomedical Applications (0707). Skill Set Knowledge Objectives 0707.1 Contributions of Biotechnology to Health and the Human Condition Students will demonstrate knowledge of Performance Objectives Students will 0707.2 0707.3 0707.4 Skill Set Knowledge Objectives 0707.5 molecular biology of disease and health. biotechnology products. quality of life related to finding cures for genetic, environmental and behavioral diseases, chronic conditions and industrial enzymes. new diagnostic tools. legal and ethical issues with emphasis on social and diversity issues. propose an industrial enzyme that could contribute to the quality of life. generate a list of environmental diseases or chronic conditions that have been or could be treated with biotechnology products. assess a current biotechnology-related ethical issue and how it may affect quality of life. Academic Foundations/Biomedical Research and Development Students will demonstrate knowledge of fundamentals of: o mathematical concepts. o statistics. o genetics. o organic chemistry. o biochemistry. o cell biology. o molecular biology. o microbiology. 10 Performance Objectives Students will 0707.6 0707.7 0707.8 0707.9 0707.10 0707.11 0707.12 0707.13 0707.14 0707.15 0707.16 0707.17 0707.18 0707.19 0707.20 0707.21 0707.22 0707.23 0707.24 0707.25 0707.26 0707.27 0707.28 0707.29 Skill Set Knowledge Objectives 0707.30 illustrate the concepts of percentages and ratios using a biotechnology application. contract weight-to-weight and weight-to-volume calculations for solutions. explain scientific notation. compare the deviation and the mean of efficacy testing data of two biotechnology products. graphically illustrate a set of biotech data in an format/illustration that a layman would understand. describe the basic structure of a chromosome. construct a karyotype with human chromosomes. differentiate the genetic inheritance of a lethal dominant homozygous trait (e.g. dwarfism) from a heterozygous disease (e.g., sickle cell anemia). construct a molecule of a compound with three or more carbon atoms. create an equation of two organic substrates leading to a product. describe atomic number, atomic mass and orbitals. contrast covalent, ionic and hydrogen bonding. diagram six chemical side groups that could be in a biotechnology product. categorize all amino acids into essential and non-essential. describe the relationship between biochemistry and biotechnology product development. compare the underlying reasons why some molecules are hydrophilic and some are hydrophobic. describe the basic structures and functions of cells and how this knowledge is used in biotechnology. select cellular barriers to be overcome for a biotechnology product to work inside a cell. diagram the structure of the nucleic acid DNA. demonstrate DNA replication graphically and its importance to biotechnology product development. describe the central dogma of molecular biology and how understanding this process impacts biotechnology research and development. analyze how microorganisms are used in mass producing recombinant proteins. compare and contrast bacterial, fungal and animal cells and how their similarities and differences affect biotechnology product development and production decisions. compare and contrast the use of plasmids in bacterial transformation and the process of plasmid DNA isolation. Introduction to Biotechnology Knowledge Areas and Techniques Students will demonstrate knowledge of recombinant DNA and genetic engineering, bioprocessing (producing recombinant DNA products on a large scale for profit), monoclonal antibody production, separation and purification of biotechnology products, nanotechnology, bioinformatics, genomics, proteomics and transcriptomics. 11 Performance Objectives Students will 0707.31 0707.32 Skill Set Knowledge Objectives 0707.33 Performance Objectives 0707.34 0707.35 describe the following techniques: o recombinant DNA. o genetic engineering. o monoclonal antibody production. o separation and purification of biotechnology products and bioprocessing. predict how nanotechnology, bioinformatics, proteomics, genomics and transcriptomics will create new career opportunities. Laboratory Protocols and Procedures Students will demonstrate knowledge of principles of solution preparation such as molarity, pH, and dilution. sterile techniques such as inoculum development and transfer. contamination control. measurement and calibration of instruments such as micropipettes and pH meters. maintaining a sanitary, safe and hazard free laboratory environment. teamwork, oral and written communication skills, problem solving, emergency lab response and biosafety protocols. Students will 0707.36 0707.40 describe how molarity relates to solution preparation. calculate the molarity of a given solution and measure the pH of this solution. -3 -8 prepare a serial dilution of a microbial culture starting with 10 going to 10 and plate onto nutrient agar petri dishes. determine the original concentration of the microbial culture. 0707.37 0707.38 distinguish the requirements of sterile techniques. 0707.39 respond to a hypothetical laboratory accident appropriately as a member of a laboratory team. Skill Set Product Design and Development Knowledge Objectives Students will demonstrate knowledge of how the product is designed. what is involved in the development of the product.. subsequent production, including the laboratory procedures and regulatory requirements. how their scope of work contributes to the resulting Research & Development at the lab bench level including pre-clinical trials, clinical trials (3 phases), product license application, regulatory process for clinical trials (current Good Manufacturing Practices [cGMPs] and Good Laboratory Practices [GLPs]) for production (cGMPs, GLPs). 12 Performance Objectives Students will 0707.41 0707.42 0707.43 0707.44 Skill Set Knowledge Objectives 0707.45 Performance Objectives 0707.46 0707.47 0707.48 0707.49 0707.50 Skill Set Knowledge Objectives 0707.51 Performance Objectives diagram the process involved in making one biotech product in an industrial setting. analyze the role of pre-clinical and clinical trials in biotechnology product development. examine the role of a Quality Assurance person in this process. define cGMP and explain why it is important in biotech production. Bioethics/ Biomedical Research and Development Students will demonstrate knowledge of the interdependence of science, technology and society. ethical, moral and legal issues related to biotech research, and product development/use in society. Students will differentiate between morality and ethics and the relationship of each to biotechnology health care product development. discuss bioethical issues related to recombinant products. contrast personal, professional and organizational ethics. comply with policies and requirements for documentation and record keeping. comply with institutional ethical policies and procedures. Safety Practices/Biomedical Research and Development Students will demonstrate knowledge of infection control. personal safety. environmental safety. common safety hazards. emergency procedures and protocols. Students will 0707.52 0707.53 0707.54 0707.55 0707.56 0707.57 0707.58 0707.59 0707.60 0707.61 explain principles of infection control. describe methods of controlling the spread and growth of microorganisms. apply personal safety procedures based on Occupational Safety and Health Administration (OSHA) and Centers for Disease Control (CDC) regulations. apply skills to obtain training and/or certification in Bloodborne Pathogen – Preventing Disease Transmission (American Red Cross). apply principles of body mechanics. apply safety techniques in the work environment. comply with safety signs, symbols and labels. understand implications of hazardous materials. practice fire safety in a healthcare setting. apply principles of basic emergency response in natural disasters and other emergencies. 13 Biomedical Innovations WVEIS HE0708 * Foundations of Health Science (0711) and Advanced Principles of Health Science (0715) provide the introductory core for all Health Science Concentrations and require a minimum course completion score of 80%. *Biomedical Applications (0707) is a prerequisite for Biomedical Innovations (0708) and requires a minimum course completion score of 80%. Skill Set Follow Regulatory Guidelines Knowledge Objectives Students will demonstrate knowledge of 0708.1 Performance Objectives basic concepts and techniques necessary to work effectively in a biotechnology laboratory. Students will 0708.2 0708.3 0708.4 0708.5 0708.6 0708.7 discuss the nature of science, lab work and the role of the biological technician. discuss basic microbiology with emphasis on the role of bacteria, viruses and fungi in human health and disease. discuss FD&C Act. discuss and follow OSHA guidelines. discuss and follow other national guidelines including, but not limited to: NIH, DOT, EPA, FDA and CDC. discuss and follow state and local regulations. Skill Set Knowledge Objectives 0708.08 Performance Objectives 0708.09 0708.10 0708.11 0708.12 0708.13 0708.14 0708.15 0708.16 0708.17 0708.18 Quality Assurance and Safety Practices Students will demonstrate knowledge of appropriate safety procedure. hazardous materials. MSDS. safety symbols and signs. safety equipment. Precautions. aseptic techniques. quality control. Students will identify first aid supplies, personnel and emergency protection areas. use appropriate safety procedures and guidelines. monitor, use, store and dispose of hazardous materials properly. follow Material Safety Data Sheets (MSDS). identify safety symbols and signs. demonstrate an ability to utilize safety equipment. follow Precautions. maintain a clean work area. practice aseptic techniques as required. discuss quality control in relation to inspection procedures, testing methods and internal audits. 14 Skill Set Knowledge Objectives 0708.19 Performance Objectives 0708.20 0708.21 0708.22 0708.23 0708.24 0708.25 0708.26 0708.27 0708.28 0708.29 Skill Set Knowledge Objectives 0708.30 Performance Objectives Demonstrate Problem Solving and Decision Making Skills Students will demonstrate knowledge of problem solving techniques. decision making techniques. algebraic equations. computation of angles and lengths. conversion between measurement systems. interpreting tables and graphs. Students will apply problem solving techniques in the workplace utilizing the scientific method. apply decision making techniques in the workplace utilizing the scientific method. solve basic shop problems using elementary math. solve single/variable algebraic equations. calculate geometric parameters such as area, circumference, perimeter and volume. compute angles and lengths using basic trigonometry. convert between measurement systems including metric. convert decimals and fractions. express ratios as percentages. interpret tables and graphs. Utilize and Maintain Equipment and Supplies Specific to Bio-medical Labs Students will demonstrate knowledge of utilization and maintenance of equipment. utilization and maintenance of supplies specific to bio-medical laboratories. safety measures. Students will 0708.31 0708.32 0708.33 0708.34 0708.35 0708.36 practice aseptic technique. recognize and describe the use of laboratory equipment including, but not limited to the following: thermocycler, microscope, fluorometer, hoods, centrifuge, polarimeter, pH meter, chart recorder, stirs, balance, mixers, conductivity meters, autoclaves, shakers, power supplies, dry heat, ovens, incubators, Bunsen burners and Geiger counters. check and maintain equipment and logs. clean, organize and sterilize materials. order and maintain inventory of supplies. handle and store biological and hazardous materials. 15 Skill Set Knowledge Objectives 0708.37 Performance Objectives 0708.38 0708.39 0708.40 0708.41 0708.42 0708.43 0708.44 0708.45 0708.46 0708.47 0708.48 Skill Set Knowledge Objectives 0708.49 Performance Objectives 0708.50 0708.51 Technical Skills/Biomedical Research and Development Students will demonstrate knowledge of solutions and reagents. physical properties of reagent, buffers and media solutions. laboratory tests. basic microbiology skills. basic immunological skills. genetic skills. chemical assays. sterilization of supplies and equipment. packaging of sterile products. bio-compatibility tests. Students will prepare solutions and reagents for laboratory use. monitor physical properties of reagents, buffers, media and solutions. set up laboratory tests. describe and/or perform basic microbiology skills. describe and/or perform basic cell biology skills. describe and/or perform basic immunological skills. describe and/or perform basic genetic skills. describe and/or perform chemical assays. sterilize supplies and equipment. package sterile products. demonstrate an understanding of bio-compatibility tests. Teamwork/ Biomedical Research and Development Students will demonstrate knowledge of health care teams. team member participation. Students will understand roles and responsibilities of team members. apply effective techniques for managing team conflict. Skill Set Knowledge Objectives 0708.52 Performance Objectives 0708.53 Phlebotomy Certification/Clinical Experience Students will demonstrate knowledge of phlebotomy technician training requirements. (WVEIS 0825) Students will complete requirements for phlebotomy technician certification. (WVEIS 0825) 16