Urinary System:The urinary system consists of the paired kidney, ureters, bladder, and urethra this system contributes of the maintenance at homeostasis by a complex process that involves filtration,active absorption passive absorption, and: secretion . the result is the production of urine in wich various metabolic waste products are eliminated. Urine produced in the kidneys passes through the to the bladder .where it is temporarily stored and then released of the exterior through the urethra the tow kidneys produce about 125 ml of filtrate per minute of this amount. 124 ml is absorbed in the organ, and only 1 ml is released into the urelers as urine. Kidney: cortex and pyramidal The kidney is subdivided and outer region,the cortex and an inner region, the medulla. externally ,the cortex is covered with aconective tissue capsule in the cortex the convoluted tubules glomeruli, straight tubules and medullary rays, are found, the cortex also contain renal corpuscles (glomerular or bowman capsule and glomeruli), the glomerulus is a tuft of capillaries formed from the afferent glomerular arterioles and supported by fine connective tissue. The visceral layer of the glomerular capsule consists of modified epithelial cells called the podocytes, these cells closely follow the contours of the glomerulus and invest the capillary tuft. At the vascular pole the visceral epithelium reflects to become the parietal layer of the glornerular capsules. the space between the visceral layer and the parietal layer of the capsule is the capsular space,which become continuous with the lumen of proximal convoluted tubule at the urinary pole Numerous tubules sectioned in various planes, lie adjacent to the renal corpuscles the tubules are primarily of two types the proximal convoluted and distal convoluted, these tubules are the initial and terminal segments of nephron, respectively. the proximal convoluted tubules are numerous in the cortex, exhibit a small ,irregular lumen,and contain a single layer of large cuboidal cells with intensely eosinophilic mgranular cytoplasm the well— developed brush borders are present but are not always well preserved in sections. Distal convoluted tubules are fewer in number and-exhibit a larger lumen with smaller ,cuboidal cells. The cytoplasm stanis less intensely and the brush borders are not present also the number of these cells are more than those in prximal tubules. The medulla: The medulla contain only straight portion of tubules and thin segments of loop of Henle. Illustrated in the outer medullary region are thin segments of loops of Henle lined with squamous epithelium straight segments ofdistal tubules(ascending have simple cuboidal ep.) and straight segments of proximal tubule (descensing have simple cuboidal ep.) and collectingtubules, in medulla contain the terminal portions of the collecting tubules, the papillary ducts ,these ducts have large diameters and wide lumina and are lined by tall, pale— staining columnar cells. Juxtaglomerular Apparatus: Adjacent to the renal corpuscle the tunica media of the afferent arteriole has modified smooth muscle. These cells are called juxtaglomerular cells and-have cytoplasm full of secretory granules secretion of JG cells play a role in the maintenance of blood pressure. The macula densa of the distal convoluted tubule is, usually located near the region of the afferent arteriole that contain the JG cells ;together, this portion of the arteriole and macula densa form the JG apparatus. the JG cells produce the enzyme rennin which regulate. the blood pressure. Bladder & Urinary passages The bladder and the urinary passages store the urine formed in the kidney and conduct it to the exterior .the calyces ,renal pelvis ,ureter, and urinary bladder have the same basic histological structure, with the walls of the ureters becoming gradually thicker as proximitry. to the bladder increases. The mucosa of the organs consists of transitional epithelium and lamina propria of loose—to- dense connective tissue. Surrounding the lumina proporia of these organs is a dense woven sheath of smooth muscule. Urethra: The urethra is a tube that, carries the urine from the bladder to the exterior.in man , the sperm also pass through it during ejaculation .. in woman the urethra is exclusively a urinary oragen