Stuff of Life Chapter 4 (pg 91 – 122)
1. What is genetic counseling?
2. How does a genetics counselor use a pedigree?
3. What contribution to our understanding of heredity is each of the following scientists credited with:
Thomas Hunt Morgan
Alfred Sturtevant
Watson & Crick
Frederick Sanger
4. When was the Human Genome Project initiated? What was its goal? How long did it take?
5. What does sequencing a genome for an organism like brewer’s yeast contribute to our understanding
of human genetics?
6. What specific knowledge has been gained from the completion of the HGP?
7. What information still needs to be sorted out?
8. What is the objective of the Cancer Genome Atlas?
9. What is the normal function of BRCA1? What happens if it is not working properly?
10. What is a mutation?
11. Are all mutations bad? Explain.
12. What is the difference between a gene mutation and a chromosomal mutation?
13. What is aneuploidy? What causes it?
14. What is the job of restriction enzymes? Ligase?
15. Outline the steps a scientist could use to create bacteria that make human insulin.
16. Outline the steps to insert therapeutic genes into a patient’s ailing cells.
17. What is a DNA library?
18. What is transgenic technology?
19. How might transgenic plants be used to help people? What are some cautions?
20. What are some possible uses for transgenic animals?
21. Do clones exist in nature? Explain.
22. Why were the apples that John Chapman planted sour and not sweet?
23. How are we able to grow sweet apples in the US today? Is that a bad thing? Explain
24. What are artificial clones? Are they all successful?