NAME
Jia, Peilin eRA COMMONS USER NAME
PEILINJIA
EDUCATION/TRAINING
BIOGRAPHICAL SKETCH
POSITION TITLE
Research Assistant Professor
INSTITUTION AND LOCATION
Dalian University of Technology, China
Shanghai Institutes for Biological Sciences,
Chinese Academy of Sciences, China
Virginia Commonwealth University
Vanderbilt University School of Medicine
A. Personal Statement
DEGREE
B.S.
Ph.D.
MM/YY
07/03
07/08
Post-doc 09/08-06/09
Post-doc 07/09-07/12
FIELD OF STUDY
Biochemistry
Bioinformatics
Bioinformatics
Bioinformatics
I obtained my Ph.D. in Bioinformatics in 2008 and have more than 8 years of bioinformatics research experience. As a post-doctoral fellow in Dr. Zhongming Zhao's lab at both Virginia Commonwealth University and Vanderbilt University, and currently as a research faculty member in the same lab, I developed bioinformatics strategies to perform advanced functional genomics analysis for data from genome-wide association studies (GWAS), constructed multi-dimensional data integration algorithms, and created the schizophrenia gene resource (SZGR) database. One of the tools I developed is the dense module search
(DMS) of enriched association signals from genome-wide association studies, which has been highly cited since its publication in early 2011. I would like to commit a major effort to this opportunity.
B. Positions and Honors
Positions and Employment
2003-2008 Research Assistant, Bioinformatics Center, Key Laboratory of Systems Biology,
Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai,
2008-2009
2009-2012
China
Postdoctoral Fellow, Virginia Institute for Psychiatric and Behavioral Genetics, Department of Psychiatry, Virginia Commonwealth University, Richmond, VA
Postdoctoral Fellow, Department of Biomedical Informatics, Vanderbilt University School of
2012-pres
Medicine, Nashville, TN
Research Assistant Professor, Department of Biomedical Informatics, Vanderbilt University
School of Medicine, Nashville, TN
Honors
2001 First Prize, the 10th Dalian Mathematics Contest for Science and Engineering College
2011
Students
NARSAD Young Investigator Award (2011-2013), Brain & Behavior Research Foundation
Program Committee member of the following conferences: International Conference on Intelligent Biology and
Medicine (ICIBM 2012), Nashville, Tennessean, April 22-24, 2012.
Journal Peer Review: PLoS ONE , BMC Medical Genomics

C. Selected peer-reviewed publications.
1. Zhao Z, Guo AY, van den Oord EJ, Aliev F, Jia P , Riley BP, Dick DM, Bettinger JC, Davies A, Grotewiel
MS, Kendler KS, Webb BT, Miles MF (accepted) Multi-species data integration and gene ranking enriches significant results in a genome-wide association study of human alcohol dependence symptoms. BMC
Genomics
2. Jia P , Liu Y, Zhao Z (2012) Integrative pathway analysis of genome-wide association studies and gene expression data in prostate cancer. BMC Systems Biology 6(Suppl S2):S13
3. Chen J, Lee G, Fanous AH, Zhao Z, Jia P , O’Neil A, Walsh D, The International Schizophrenia
Consortium, Kendler KS, Chen X (2011) Two non-synonymous markers in PTPN21, identified by genomewide association study data-mining and replication, are associated with schizophrenia. Schizophrenia
Research 131(1-3): 43-51
4. Jia P , Ewers J, Zhao Z. (2011) Prioritization of Epilepsy Associated Candidate Genes by Convergent
Analysis. PLoS ONE 6(2):e17162
5. Sun J, Wan C, Jia P , Kendler KS, Riley BP, Zhao Z. (2011) Application of systems biology approach identifies and validates GRB2 as a risk gene for schizophrenia in the Irish Case Control Study of
Schizophrenia (ICCSS) sample. Schizophrenia Research 125:201-208
6. Jia P , Zheng S, Long J, Zheng W, Zhao Z (2011) dmGWAS: dense module searching for genome-wide association studies in protein-protein interaction networks. Bioinformatics . 27(1) 95-102
7. Adkins DE, Åberg K, McClay JL, Bukszár J, Zhao Z, Jia P , Stroup ST, Perkins D, McEvoy JP, Lieberman
JA, Sullivan PF, van den Oord E. (2011) Genomewide pharmacogenomic study of metabolic side effects to antipsychotic drugs. Molecular Psychiatry 16(3):321-332
8. Sun J, Jia P , Fanous AH, van den Oord EJCG, Chen X, Riley BP, Amdur RL, Kendler KS, Zhao Z. (2010)
Schizophrenia gene networks and pathways and their applications for novel candidate gene selection.
PLoS ONE 5:e11351
9. Jia P , Sun J, Guo AY, Zhao Z. (2010) SZGR: A comprehensive schizophrenia gene resource. Molecular
Psychiatry 15: 453-462
10. Sun J, Jia P , Fanous AH, Webb BT, van den Oord EJCG, Kendler KS, Zhao Z. (2009) A multi-dimensional evidence-based candidate gene prioritization approach for complex diseases – Schizophrenia as a case.
Bioinformatics 25: 2595-2602
11. Jia P , Qian Z, Feng K, Lu W, Li Y, Cai Y. (2008) Prediction of membrane protein types in a hybrid space.
Journal of Proteome Research 7: 1131-1137
12. Wei W, McCusker JH, Hyman RW, Jones T, Ning Y, Cao Z, Gu Z, Bruno D, Miranda M, Nguyen M,
Wilhelmy J, Komp C, Tamse R, Wang X, Jia P , Luedi P, Oefner PJ, David L, Dietrich FS, Li Yixue, Davis
RW, Steinmetz LM. (2007) Genome sequencing and comparative analysis of Saccharomyces cerevisiae strain YJM789. Proc Natl Acad Sci USA 104:12825-12830
13. Jia P , Qian Z, Zeng Z, Cai Y, Li Y. (2007) Prediction of subcellular protein localization based on functional domain composition. Biochemical and Biophysical Research Communications 357: 366-370
14. Wei W, Cao Z, Zhu YL, Wang X, Ding G, Xu H, Jia P , Qu D, Danchin A, Li Y. (2006) Conserved genes in a path from commensalism to pathogenicity: comparative phylogenetic profiles of Staphylococcus epidermidis RP62A and ATCC12228. BMC Genomics 10, 7:112
15. Jia P , Shi T, Cai Y, Li Y. (2006) Demonstration of two novel methods for predicting functional siRNA efficiency. BMC Bioinformatics 29, 7:271
D. Research Support.
Ongoing Research Support
NARSAD (Jia) 07/15/2011-07/14/2013
National Alliance for Research on Schizophrenia and Depression Young Investigator Award
“An integrative genomic study of schizophrenia”
Role: Principal Investigator