Queensborough Community College, The City University of New York
BI-356 Principles of Genetics
Course Description: BI-356 Molecular and general genetics. DNA structure, function,
replication, mutations, recombinant DNA technology, RFLPs, cloning strategy and
application. Gene structure, regulation genetics code in prokaryotic and eukaryotic systems.
Mendelian genetics and its application to population genetics.
INSTRUCTOR: Dr. Nidhi Gadura NGadura@qcc.cuny.edu Office M425 x6078
Office Hours: Tues 1-2, Thursday 12-1, Wed 9-10
Course TEXT:
GENETICS
Analysis and Principle
By Robert J. Brooker, 4th edition
McGraw Hill
Course Objective: I hope by the end of the semester, I have accomplished teaching you the
fundamental principles of genetics. Molecular genetics will be taught starting from classical
discoveries and how those led to a burst of new technology and scientific tools used in the
labs around the world today. No genetics class will be complete without learning Mendelian
principles of inheritance so we will save the best for last and learn Mendelian genetics by the
end of the semester.
Week
Topic
Chapter
1
Introduction – History of Genetics
Review of all the background material
Ch 1
2
Structures of Nucleic Acids
Watson-Crick Model contd.
Ch 9
3
Exam I Replication of ds DNA molecule
Ch 11
4
Prokaryotic and Eukaryotic Chromosome Structure
and Function
Ch 10
5
Variation in Chromosome Structure and Mutations
Ch 8
6
Exam III DNA Transcription, Gene Structure, and
organization
Ch 12
7
Translation, Protein Synthesis
Ch 13
8
Exam III Recombinant DNA Technology
Plasmids, Cloning, BACs and YACs
Ch 18
9
DNA Mutation, Damage & Repair
Ch 16
10
Exam IV Prokaryotic Gene Regulation
Ch 14
11
Eukaryotic Gene Regulation
Ch 15
12
Exam V Mendel’s Law of Inheritance, Problem
Solving, Dihybrid crosses
Ch 2
13
The Chromosomal Theory of Inheritance
Ch 3
14
Extensions of Mendelian Inheritance
Ch 4
15
Genetic Linkage and Mapping, Chi Square Analysis
Exam VI
Ch 5
Grading Policy:
6 Exams - 10% each
(Exams are 45 min each and start promptly DON’T be LATE for class)
Homework - 20%
(Graded Online HW problems on BB due Thur – Tue every week!!)
3 Writing assignments– 15%
(Due Weeks 4, 7 & 13 Topics announced on BB and assignments submitted via
SafeAssign on BB)
Online BB Discussion Participation – 5%
(You will be assigned a Group on Discussion Board, you are expected to log on
every week, read assigned material and discuss the topic on BB)
MAKEUP EXAMS ONLY GIVEN UPON DOCUMENTED EMERGENCY
SITUATIONS. Please email NGadura@qcc.cuny.edu ASAP!!
QCC Academic Integrity Policy Statement
http://www.qcc.cuny.edu/Governance/AcademicSenate/COAI/Docs/Academic_Integrity
_Document.pdf
 Cheating
 Citation of information not taken from the source indicated. This may include the
incorrect documentation of secondary source materials
 Listing sources in a bibliography that are not directly used in the academic exercise
 Submission in a paper, thesis, lab report or other academic exercise of falsified,
invented, or fictitious data or evidence, or deliberate and knowing concealment or
distortion of the true nature, origin or function of such data or evidence
 Submitting as your own any academic exercises (e.g., written work, printing, musical
composition, painting, sculpture, etc.) prepared totally or in part by another
 Cheating is an act or an attempted act of deception by which students seek to
misrepresent that they have mastered information on an academic exercise that they
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have not mastered. Examples of cheating include but are not limited to:
Copying from another student's test paper Allowing another student to copy from a test
paper
Unauthorized use of course textbook or other material such as a notebook or notes in
any form to complete a test or other assignment
Collaborating on a test, quiz or other project with any other person(s) without
authorization
Using or possessing specifically prepared but unauthorized materials during a test, e.g.,
notes, formula lists, notes written on the student's clothing, study aids, electronic or
other devices or any unauthorized communication during an academic exercise,
preparing answers or writing notes in an exam booklet before an examination.
Using electronic instruments, such as cell phones, pagers, etc., to obtain or transmit or to
share information, when prohibited
Participating in any academic exercise such as a test using the name of another person
or permitting someone else to participate in such an exercise for oneself.
Students with Disabilities
http://www.qcc.cuny.edu/SSD/
A student should make an initial request for accommodation to the Office of Services for
Students with Disabilities, and provide appropriate supporting documentation. The
Student Disabilities Services Coordinator may consult with appropriate college officials
such as the instructor or provost to determine the appropriateness of the requested
accommodation consistent with the program requirements. Such consultation shall be
confidential, and limited to those officials whose input is necessary to the decision.