11th Grade Biology Course Outline – 09/01 to 09/24 Day 1 – Tuesday 09/01 COURSE INTRO: Grading, assignments and tests, deadlines, themes and purpose LECTURE/DISCUSSION/NOTES: Review: The Mechanisms of Inheritance Cell Division Cycles: Mitosis and Meiosis The Structure of DNA/Chromosomes LAB: Begin Genetics of Drosophila Lab (Activity A) (LAB #1) Day 2 – Wednesday 09/02 LECTURE/DISCUSSION/NOTES: Mendelian Genetics and The Gene Idea Mendel’s Biography, setting the context Mendel’s Experimentation Dominant and Recessive Traits The Law of Probability and Punnet Squares: Single Crosses LAB: Genetics of Drosophila Lab (Activity B) (LAB #1) WORKSHEET/ACTIVITY: Single Cross Punnet Squares Day 3 – Thursday 09/03 LECTURE/DISCUSSION/NOTES: Mendelian Genetics The Law of Segregation Dihybrid Crosses and the Law of Independent Assortment LAB: Environmental Influence on fungi Phenotypes (Inoculation of Fungi Habitats) (LAB #2) WORKSHEET/ACTIVTY: Dihybrid Crosses Day 4 – Friday 09/04 LECTURE/DISCUSSION/NOTES: Beyond Mendelian Genetics Biosynthesis Pathways; The Relationship Between Dominance and Phenotype The Spectrum of Dominance: Incomplete, Complete, and Co- dominance Multiple Alleles, Pleiotropy, Epistasis, and Ploygenetic Inheritance LAB: Genotype – Phenotype Connection: Basic Molecular Genetics (Activity 1) (LAB #3) HW: Read The Path of Reduction: Mendel’s Initial Steps Day 5 – Tuesday 09/08 LECTURE/DISCUSSION/NOTES: Quiz #1 Review Discussion of Reading: The Path of Reduction: Mendel’s Initial Steps LAB: Fingerprinting Virus DNA (LAB #4) Day 6 – Wednesday 09/09 Quiz #1: Mendelian Genetics LAB: Fingerprinting Virus DNA – Results and Analysis (LAB #4) Day 7 – Thursday 09/10 LECTURE/DISCUSSION/NOTES: DNA Structure and Function DNA Replication (with experiments by Hershey/Chase and Griffith) Day 8 – Friday 09/11 LECTURE/DISCUSSION/NOTES: RNA, DNA & Protein Synthesis: The Central Dogma Transcription: RNA Synthesis and Functions Translation: Protein Biosynthesis LAB: Genetics of Drosophila (Activity C) (LAB #1) Day 9 – Monday 09/14 LECTURE/DISCUSSION/NOTES: The Central Dogma of Molecular Biology LAB (4): Genotype – Phenotype Connection: Basic Molecular Genetics (Activity 2) (LAB #3) Day 10 – Tuesday 09/15 LECTURE/DISCUSSION/NOTES: Midterm Review Restriction Enzymes and PCR Tech. Introduction to Epigenetics: NOVA Video from learn.genetics.utah.edu LAB: Genotype – Phenotype Connection: Basic Molecular Genetics (Activity 3) (LAB #3) Day 11 – Wednesday 09/16 MIDTERM: Mendelian Genetics, DNA Replication, Transcription/Translation & Protein Functions Epigenetics: PBS Video with Neil Degrass Tyson Day 12 – Thursday 09/17 LECTURE/DISCUSSION/NOTES: Epigenetics: Lamarckism and Darwinian Evolution LAB: Genetics of Drosophila (Activity D, if ready) (LAB #1) Day 13 – Friday 09/18 MIDTERM RESULTS: Discussion and Questions LECTURE/DISCUSSION/NOTES: Epigenetics: Mutations and Gene Expression/Regulation Finish Nova Video on Epigenetics LAB: Environmental Influence on Fungi Phenotypes (Results and Analysis) (LAB #2) Final Study Guides handed out!!! Day 14 – Monday 09/21 LECTURE/DISCUSSION/NOTES: Epigenetics: Recent Studies, DNA Methylation & Histone Modification LAB: Genetics of Drosophila (Activity D&E): Results and Analysis (LAB #1) Day 15 – Tuesday 09/22 LECTURE/DISCUSSION/NOTES: The Arc of Evolution on Earth Final/Course Review Start Video: GATACCA Day 16 – Wednesday 09/23 LECTURE/DISCUSSION: The Arc of Evolution on Earth Discussion: Nature, Nurture and Freedom Finish Video: GATACCA Day 17 – Thursday 09/24 FINAL: Cumulative TURN IN MLBs (by 09/25)