Chief Complaint: Dizziness HISTORY OF PRESENT ILLNESS: A 67-year-old woman presents with a 6 months history of 12/07 nausea, vomiting and epigastric gnawing discomfort related to newly diagnosed gastroparesis for which GI started her on metaclopramide. This has helped though she still reports, "Feeling bad". Her oral intake has definitely decreased resulting in gradual loss of weight. Four months ago, she started having symptoms of dizziness upon standing, which has progressively worsened. One week ago she noted a right axillary lump though to be an enlarged lymph node though excisional biopsy revealed the mass to be a hematoma. At this point she is essentially bed bound getting up to go to the bedside toilet due to her substantial fear of falling. Past Medical & Surgical History: 1. Status post hysterectomy in 1986. Allergies/Reactions: None known. MEDICATIONS: 1. Nexium 40 mg before meals. 2. Reglan 10 mg before meals. 3. Multivitamin once daily. Social History: Married and lives with husband. No tobacco, alcohol, or recreational drug abuse history. Family History: Father had aplastic anemia Daughter ITP as a child, in remission Brother died of lung cancer. REVIEW OF SYSTEMS: Constitutional: No fevers, chills or sweats. Appetite marginal with gradual weight loss as per HPI Head: No headaches. Eyes: No visual acuity change, blurred vision, diplopia or ocular pain. ENT: No reduced hearing, tinnitus, or ear drainage. No nasal congestion or discharge. No epistaxis. Mouth/throat: No oral lesions, odynophagia, dysphagia. Heme/Lymph: Bruises easily. No enlarged lymph nodes noted except as per HPI. Cardiovascular: No chest pain but severe dizziness as noted above. No orthopnea or paroxysmal nocturnal dyspnea. No lower extremity swelling. Respiratory: No shortness of breath, cough, sputum productivity. Gastrointestinal: Negative except as per HPI. Genitourinary: No dysuria, urgency or frequency. No hematuria. Musculoskeletal: No muscular pains or weakness. No focal bone or back pain. Neuro: No focal motor or sensory deficits. No seizures. No stroke. PHYSICAL EXAMINATION BP: 129/69 P: 86 (supine) BP: 95/53 P: 81 (sitting) BP: 50/34 P: 86 (standing) O2 sat: 95% on room air Constitutional: Chronically ill-appearing female in NARD. Appears dizzy on standing. HEENT: Eyes: PERRL. EOMi. Nonicteric sclerae. Pink conjunctivae. Oropharynx: Oral mucosa is moist and pink without lesions, erythema, or exudates, drainage or tonsillar enlargement. Neck: No thyromegaly or masses. Lymphatics: NO LAD all areas Respiratory: CTA bilaterally. Normal chest excursion Cardiovascular: Regular S1, S2 with a 2/6 SEM. No rub or gallop. Abdomen: BS+. Soft NTND. No HSMY or masses. Extremities: No CCE Skin: Bruising over the forearms and legs bilaterally. Left axillary bruise at sire of recent biopsy—incision healing well. CURRENT LABORATORY & RADIOLOGY STUDIES Chemistries: Na 133, K 3.8, Cl 99, Bicarb 30, BUN 13, Cr 0.7, Glu 120, Ca 8.2 AST 52, ALT 61, Alk phos 161, Total bili 0.4, Prot 6.1, Alb 3.1, Prealbumin 27.2 CK is 31, CKMB 4, Troponin-I 0.07, with BNP 682. CBC: Hgb 11.1, Hct 34, MCV 89.7, WBC 8 with a normal differential, and Plts 272 Coags: PT 14.9 sec, INR 1.5, PTT 52 sec. Thrombin Time 17 sec PTT 1:1 mixing study 34 sec Factor VIII 94% Factor IX 87% Factor XI 63% Urine analysis: Trace blood (5 RBC/HPF), Protein >300, $+ hyaline casts, 1+ bacteria otherwise negative Transthoracic ECHO Concentric left ventricular hypertrophy with normal cavity size and systolic function. There is mild ventricular hypertrophy. Right ventricular systolic function is normal. The filling pattern of the ventricles is not suggestive of restrictive physiology. The left atrium is mildly dilated. Small pericardial effusion.