Five Forces Analysis: Pharmaceutical Industry Five Forces Analysis: Pharmaceutical Industry MSOD 617 | Pepperdine University Sikin Samji Rachel Purcell Karen Portillo Five Forces Analysis: Pharmaceutical Industry A report by Price Waterhouse Cooper (PwC, 2012, pg. 5) estimates that by 2020, the market for medicine could be worth $1.6 trillion, potentially more as the global population increases, ages and becomes more sedentary. On a global level, the pharmaceutical industry continues to steadily grow, with sales reaching $1.08 trillion in 2011 – a year-on-year increase of 7.8%. Sales in the BRIC countries (Brazil, China, India and Russia) rose by 22.6%, while sales in 13 other growth countries rose by 7.2% (PwC, pg. 5). Many leading pharmerging markets, including: Brazil, India, Turkey, Mexico, Russia, South Korea, China, Venezuela, Chile, Vietnam, and the Czech Republic, also show double-digit growth rates due to economic growth, demographic and epidemiologic changes, along with improved state and private insurance funding for healthcare and medicines (IMS Institute for Healthcare Informatics, 2013, pg. 1). These emerging markets are, however, limited by affordability of pharmaceuticals for the growing population. Generic spending in particular is forecasted to rise by $35-40 billion over the next five years with 60% of the increase resulting from greater utilization of existing generics. Sales are growing in mature markets at a more sluggish rate than growth in emerging markets, being primarily hindered by pricing pressures and increasing regulation. However, the overall high profitability in the industry, coupled with advances in genetics and genomics, technology, a strengthening scientific base, and growing demand for medicines make this an attractive industry to invest in. New Entrants The threat of new entrants to the industry is moderate. Newcomers face various barriers such as high research and development costs, and government regulations. The high cost of developing a new drug comes with the risk that once completed it may not be approved by the government’s agencies (IMS Institute for Healthcare Informatics, 2013). Tighter government regulations also influence a firm’s ability to enter the industry. Regulators around the globe are Five Forces Analysis: Pharmaceutical Industry collaborating more, so a product in one region is more likely to be rejected in others. As an example, in 2010, the European Medicines Agency pulled diabetes drug Avandia, while the Food and Drug Administration imposed restrictions on its use. Both agencies swapped information before reaching a decision. 24 countries thus far have introduced laws or codes of conduct requiring pharma companies disclose any interactions with healthcare professions who are also customer (PwC, 2012, pg. 6). Patents can also act as a deterrent to entry. Even with many expiring in the coming years, many large pharmaceutical companies invest heavily in generics prior to their patents expiring in order to beat out the competition. Branding is also critical in the industry to build and/or maintain customer loyalty and brand reputation. Bargaining Power of Suppliers and Customers A large number of suppliers can be found anywhere along the supply chain, eroding the power suppliers have over raw materials and distribution. Differentiators for successful companies include having an integrated supply chain (PwC Supply Chain Survey, 2013). This can potentially increase switching costs for these organizations. Overall, the industry outsources product development 25% of the time (PwC, 2012). Outsourced manufacturing facilities can produce multiple and varying medical products including prescription, generic, and over-thecounter; allowing the industry not to rely upon a single source. The bargaining power of the customer depends on size, with large customers such as hospitals having more power than individual consumers. Increasing regulatory pressures are causing a shift. For example, Healthcare Reform in the U.S. will shift toward ACOs (accountable care organizations) which holds providers (i.e. doctors) accountable for the services they provide, thus transferring the buying power toward the doctors as they will hold pharmaceuticals Five Forces Analysis: Pharmaceutical Industry to similar standards. In a survey by PwC, four-fifths of U.S. health insurers polled now require evidence of cost savings or a clinical benefit to include new products in their formularies (or reimbursed drug list). 16% have also entered into outcomes-based contracts with pharmaceutical companies and another 33% expected to do so in the next three years. In addition, the rise in social media allows customers access to more information on treatment alternatives. According to a 2012 survey by PwC, 16% of U.S. adults said they post reviews of their treatments on social media. Substitutes Threat of substitutes is low to moderate. Many drugs are set to come off patent by 2015, causing an expected increase in the use of generic drugs (U.S. Food and Drug Administration). Drugs going off-patent in 2014 contribute just under $50 billion in pharmaceutical revenue. However, not all products losing protection face imminent competition from generics; biological products and drugs delivered by devices are best poised to extend their money-spinning streak (Bloomberg Businessweek, 2013). Industry Rivalry Competition in the industry is high; companies currently spend one-third of all sales revenue on marketing their products, roughly twice what they spend on research and development. The 10 largest drug companies control over one-third of the market. According to a 2014 report from Marketwatch, executives from the global pharmaceutical industry anticipate an increase in levels of consolidation, with 61% of respondents projecting an increase in mergers and acquisition activities in 2013. The need for new products pipelines, new product acquisition, patent expiries, cost containment and credit availability have prompted companies to consolidate positions and look for mergers and/or possible acquisitions. Five Forces Analysis: Pharmaceutical Industry Sanofi Sanofi is a French pharmaceutical company with over 110,000 employees located in over 100 countries worldwide. The Company is currently ranked the fifth largest pharmaceutical company based on 2013 sales (www.fiercepharm.com). In June 2013, Sanofi was voted first for Investor Relations in the Pharmaceutical & Biotechnology sector in Europe and first in France in the EXTEL Survey. Sanofi ranks first for the fourth year in a row in these two categories. The Company ranks first in emerging markets with a 5.7% market share and is number one in BRIC countries (en.sanofi.com). Company Strategy The Company initiated a new strategy in 2008 after the expiration of a number of patents. Since that time, the Company has shifted its position from a traditional pharmaceutical company to a bio-pharmaceutical company with 45% of sales from biologics and 80% of the development pipeline now also in biologics (up from 26% in 2008). The development portfolio includes 9 possible launches over the next 4 years (en.sanofi.com). The Company’s shift in strategy is consistent with breakthroughs in science enhancing the opportunities of biologics in pharmaceutical development. In connection with this strategy, the Company has focused on seven strategic platforms: Emerging Markets, Vaccines, Diabetes Solutions, Consumer Healthcare, Genzyme (rare diseases and multiple sclerosis), Animal Health and Other Innovative Products. Focusing on these platforms supports sustainable growth, as these platforms are less exposed overall to patent expirations. Revenue from these platforms now exceeds 70% of the Company’s overall sales. Five Forces Analysis: Pharmaceutical Industry The Company’s partnership with the Bill and Melinda Gates Foundation is an example of how the Company is focusing on the emerging markets. The purpose of this collaboration is to explore and develop new platforms and methods so as to accelerate new R&D vaccines. With this collaboration, both intend to accelerate the research and development of effective and affordable vaccines that will ultimately benefit the world’s poorest people (Sanofi Annual Review 2013). Industry Position With this new strategy, the company is positioning itself within the industry by exploiting the changes that the industry is experiencing. The company recognizes the shifting growth potential in the emerging markets and is focusing its R&D efforts on products with wide marketability. For example, the Company has nine potential vaccine filings for 2014-2018 including the world’s first dengue vaccine which impacts approximately 2.5 billion at-risk men, women and children in over 100 countries (en.sanofi.com). Financial results for the Company have lagged the industry over the last few years due to revenue decrease caused by expired patents on certain older drugs and the continued pricing pressures of governments. Company net income decreased from 2011 (8,748€) to 2013 (6,687€) as a result of patent expirations in the U.S. for products such as Plavix®. The Company’s sales over the last twelve months decreased 2.96% compared to industry growth of 12.93%. The Company’s price per sales of $3.58 is below industry average of $4.35. In addition, the Company’s price per earnings for the last twelve months is $28.59, which is below the industry average of $32.84. The Company’s earnings per share for the most recent quarter of $74.92 exceed industry average of $31.25; however, the Company’s debt to equity ratio (28.65) is higher than industry average (10.25) indicating that it is capitalized with more debt and less Five Forces Analysis: Pharmaceutical Industry equity than its peers and thus have higher earnings for each shareholder. The Company’s higher dividend yield supports this conclusion. The Company’s gross margin (67.10%) and operating margin (16.96%) both exceed industry averages of 51.47% for gross margin and 14.24% for operating margin. This indicates that the Company has been effective in keeping its costs lower than its peers thus supporting their strategy to focus on less patent intensive business platforms. The Company’s new strategy to focus on biologics and emerging markets appears to be an appropriate adjustment according to the industry movement. However, their financial results have not yet demonstrated the benefit of the new strategy. According to Reuters.com, the analysts’ consensus recommendations for Sanofi is “buy” or “outperform”, giving indication that analysts believe the new strategy will lead to growth in the future. Conclusion Sanofi is an organization that has adjusted its position within the pharmaceutical industry by exploiting the changes occurring in the global markets. The Company was stuck in 2008 with sluggish sales impacted by expiring patents of older pharmaceuticals. The old strategy of being a traditional pharmaceutical that relied heavily on patents was keeping the Company in the middle of the “big pharm” industry. As the Company adopted the newer, platform-focused strategy and emerged as a biopharmaceutical company, the organization has positioned itself to compete in the evolving global pharmaceutical industry. The financial benefits of this shift have yet to be recognized, however industry analysts seem to support this new strategy as they expect the organization to outperform its peers. Five Forces Analysis: Pharmaceutical Industry Bibliography Armum, P.A. (2014). IMS Offers a Subdued Outlook for the Global Pharmaceutical Industry at DCAT Week 14. Retrieved from http://connect.dcat.org/blogs/patricia-vanarnum/2014/03/25/ims-offers-a-subdued-outlook-for-the-global-pharmaceutical-industry. on September 11, 2014 Bloomberg Businessweek Companies & Industries. (2013). Big Pharma’s Patent Cliff. Retrieved from http://www.businessweek.com/articles/2013-11-14/2014-outlook-big-pharmadrugs-going-off-patent on September 17, 2014 Business Data Screener. (2013). Porter 5 Forces. Retrieved from www.businessdatascreener.com/industries/porter-5-forces on September 11, 2014 Express Pharma. Global Pharmaceutical Market Outlook 2015. (2001). Retrieved from http://pharma.financialexpress.com/20120115/market02.shtml on September 17, 2014 FiercePharma. (2013). Sanofi Uses Multi-Pronged Strategy To Defend Its Place In Diabetes Market. Retrieved from www.fiercepharm.com on September 21, 2014 IMAP Healthcare Report. Pharmaceutical & Biotech Indsutry Global Report – 2011. (2011). Retrieved from http://www.imap.com/imap/media/resources/IMAP_PharmaReport_8_272B8752E0FB3. pdf. on September 11, 2014 IMS Institute for Healthcare Informatics. (2013). The Global Use of Medicines: Outlook Through 2017. Retrieved from http://www.imshealth.com/deployedfiles/imshealth/Global/Content/Corporate/IMS%20H ealth%20Institute/Reports/Global_Use_of_Meds_Outlook_2017/IIHI_Global_Use_of_M eds_Report_2013.pdf on September 11, 2014 Marketwatch. (2014). Global Pharmaceutical Survey 2013-2014 – Market Trends, Buyer Spend and Procurement Strategies in the Global Pharmaceutical Industry. Retrieved from http://www.marketwatch.com/story/global-pharmaceutical-survey-2013-2014-markettrends-buyer-spend-and-procurement-strategies-in-the-global-pharmaceutical-industry2014-07-15 on September 17, 2014 Price Waterhouse Cooper (PwC). (2012). From Vision to Decision: Pharma 2020. Retrieved from http://www.pwc.com/gx/en/pharma-life-sciences/pharma2020/industry-challengesand-issues.jhtml on September 13, 2014 Reuters. (2014). Financial Highlights. Retrieved from www.reuters.com/finance/stocks/financialhighlights?symbol=SNY.N on September 21, 2014 Five Forces Analysis: Pharmaceutical Industry Roland Berger Strategy Consultants. (2013). Retrieved from http://www.rolandberger.com/press_releases/513press_archive2013_sc_content/Pharmaceutical_industry_in_a_strategic_crisis.html on September 11, 2014 Sanofi Annual Review. (2013). Retrieved from http://sanofi.publispeak.com/annual-review2013 on September 21, 2014 Sanofi. (2014). Our Strategy. Retrieved from http://ensanofi.com/our company/our strategy/ our strategy.aspx on September 21, 2014 Sanofi. (2014). Retrieved from http://en.sanofi.com/images/36039 FYR2013 Infographic.pdf on September 21, 2014 Sanofi. (2014). Investor Relations Awards. Retrieved from http://en.sanofi.com/investors/awards/awards.aspx#para on September 21, 2014 Sanofi. (2014). Chief Executive Touts Organic Growth Strategy. Retrieved from www.ft.com/intl/cms/s/0/539168e6-cf80-11e3-bec600144feabdc0.html#axzz3EIC9fGXA on September 21, 2014The Pharmaceutical Industry. Retrieved from http://www.best-information.eu/international-marketingstrategies/Appendix-B.html on September 11, 2014 U.S. Food and Drug Administration. (2012). Facts About Generic Drugs. Retrieved from http://www.fda.gov/drugs/resourcesforyou/consumers/buyingusingmedicinesafely/unders tandinggenericdrugs/ucm167991.htm on September 11, 2014 Venture Navigator. A Recent History of the Pharmaceutical Industry – Based on All Five Forces. (2007). Retrieved from http://www.venturenavigator.co.uk/content/154 on September 11, 2014 World Health Organization. (2014). Pharmaceutical Industry. Retrieved from http://www.who.int/trade/glossary/story073/en/ on September 11, 2014 Five Forces Analysis: Pharmaceutical Industry Appendix A Five Forces Analysis: Pharmaceutical Industry Five Forces Analysis: Pharmaceutical Industry Appendix B Sanofi Financial Ratios: (Source: Reuters.com) Company 28.59 3.58 17.17 3.37% Industry 32.84 4.35 27.07 1.45% Sector 33.70 5.14 27.05 1.42% Sales (TTM) vs TTM 1yr ago Sales (MRQ) vs Qtr 1 yr ago EPS (MRQ) vs Qtr yr ago -2.96% 0.74% $74.92 12.93% 8.35% $31.25 12.94% 8.55% $31.62 Current Ratio Total Debt to Equity 1.43 28.65 2.46 10.25 2.52 13.02 67.10% 16.96% 51.47% 14.24% 51.03% 12.01% P/E Ratio (TTM) Price to Sales Price to Cash Flow Dividend Yield Gross Margin (TTM) Operating Margin (TTM)