Department of Electrical & Computer Engineering 323 Martin Luther King Blvd. Newark, NJ 07102 Phone: 973-596-6594 Hand-held Optical Coherence Tomography for Intraoperative Applications Dr. Xuan Liu, Johns Hopkins University Seminar February 13, 2013 11:30 AM, 202 ECEC Abstract Optical coherence tomography (OCT) is a three-dimensional, high speed, high resolution imaging modality with a broad range of biomedical applications. For example, OCT has become a standard diagnostic device in clinical ophthalmology. Besides diagnosis, OCT also has great potential in surgical guidance. For example, a miniature OCT probe based on fiber-optic components can be integrated with a conventional surgical instrument for hand-held scanning. Such small, light-weight OCT probe can offer surgeon with freedom to access imaging sites of interest with large field of view in limited space and thus provide real-time intraoperative imaging and sensing capability to enhance surgical outcome. In the past few years, my research focus has been hand-held OCT system for intraoperative applications. In this presentation, I will show a few examples of our research efforts for the development of intraoperative hand-held OCT, including probe fabrication, motion artifact correction and novel algorithms for OCT signal processing. Biographical Information Xuan Liu received her B.S. degree in Electronics Engineering and M.S. degree in Physics in 2005 and 2007, respectively, from Tsinghua University, Beijing, China. After that, she came to the United States to study at the Johns Hopkins University. After she obtained her Ph.D. degree in electrical engineering in 2011, Xuan Liu has been working as a postdoctoral research fellow. Her research interest is biomedical engineering, especially optical coherence tomography