Biology 12 p509-516, p520 Name: ______________ Chap 25 Review Questions Date: _______________ 1. Which of the following cell structures is the site of DNA replication? A. nucleus B. ribosome C. nucleolus D. rough endoplasmic reticulum 2. Which of the following events occurs during DNA replication? A. Deoxyribose bonds to phosphate. B. Hydrogen bonds are formed between the original nucleotides. C. Bonds form between the DNA nucleotides and RNA nucleotides. D. Phosphates of the original nucleotides bind to those of the new nucleotides. Use the following diagram to answer question 3 3. What has occurred to this molecule to cause it to change as shown A. Ionic bonds have broken between deoxyribose molecules. B. Hydrogen bonds have been broken between nitrogenous bases. C. New bonds have formed causing the molecule to change shape. D. Covalent bonds have been broken between phosphate molecules. 4. In an experiment, a molecule known to be a competitive inhibitor to the enzyme helicase is added to a culture of actively dividing cells. Which of the following would likely occur? A. The cells would reproduce more rapidly. B. The rate of transcription would increase. C. The rate of DNA production by cells would decrease. D. The amount of free nucleotide molecules in the cells would decrease. 5. Which of the following molecules contains anticodons? A. DNA B. tRNA C. mRNA D. amino acid 6. Which molecule is not composed of nucleotides? Use the diagram below A. W B. X C. Y D. Z 6 7. What event is shown in the diagram to the side A. Replication B. Translation C. Transcription D. mutation 8. A tRNA molecule with the anticodon GCU would be carrying the amino acid: codon would be CGA A. valine B. tyrosine C. alanine D. arginine 9. Which of the following is NOT a frameshift mutation of the nucleotide sequence CATUAUCCC? Typo!! No T and U in the same sequence! (& all frameshift mutations) a) CATTUAUCCC c) CTUAUCCC e) CCATUAUCCC b) ATUAUCCC d) CATUAUCCGC 10. A strand of DNA has the following bases: C A C G G C C . If a frameshift mutation occurred & the adenine base was deleted, which amino acids would be coded for? DNA: C C G G C C mRNA: G G C C G G amino acid: glycine arginine 11. Fill in the following table: (3) DNA C C A C A T T A A mRNA G G U G U A A U U anticodon C C A C A U U A A amino acid GLYCINE VALINE ISOLEUCINE 12a. What is the difference between a mutagen and a mutation? A mutagen is a factor that causes a mutation. A mutation is a change in the order of bases in a sequence of DNA (in a gene) b. List 2 examples of mutagens & 2 types of mutations. Mutagens: X-ray radiation or chemicals in cigarettes Types of Mutations: Frameshift or Point Mutation 13. Put phrases 1 - 6 in the correct order to describe protein synthesis: (1) 1. 2. 3. 4. 5. 6. mRNA is produced in the nucleus ribosomes move along mRNA DNA has a code polypeptide results tRNA brings amino acids to ribosomes mRNA moves to ribosomes ORDER: 3. 1. 6. 5. 4. 2. DNA has a code mRNA is produced in the nucleus mRNA moves to ribosomes tRNA brings amino acids to ribosomes polypeptide results ribosomes move along mRNA 14. Compare the Structure of RNA to DNA RNA- ribose sugar, Uracil instead of Thymine, A, G, C bases, single stranded, sugar phosphate backbone DNA- deoxyribose sugar, Thymine NOT uracil, A, G, C bases, double stranded, Sugar phosphate backbone, hydrogen bonding holds 2 strands together, double helix shape.