Electronic Supplementary Material 1 Genetics and brain morphology Lachlan T. Strike1*, Baptiste Couvy-Duchesne1, Narelle K. Hansell1, Gabriel Cuellar-Partida, Sarah E. Medland, Margaret J. Wright Lachlan T. Strike, Baptiste Couvy-Duchesne Neuroimaging Genetics, QIMR Berghofer Medical Research Institute, Brisbane QLD 4006, Australia School of Psychology, University of Queensland, Brisbane QLD 4072, Australia Centre for Advanced Imaging, University of Queensland, Brisbane QLD 4072, Australia Narelle K. Hansell Neuroimaging Genetics, QIMR Berghofer Medical Research Institute, Brisbane QLD 4006, Australia Gabriel Cuellar-Partida Statistical Genetics, QIMR Berghofer Medical Research Institute, Brisbane QLD 4006, Australia Sarah E. Medland Quantitative Genetics, QIMR Berghofer Medical Research Institute, Brisbane QLD 4006, Australia Margaret J. Wright Neuroimaging Genetics, QIMR Berghofer Medical Research Institute, Brisbane QLD 4006, Australia School of Psychology, University of Queensland, Brisbane QLD 4072, Australia 1 * LS, BCD and NH contributed equally to this work. Corresponding author Lachlan T. Strike Lachlan.Strike@qimrberghofer.edu.au Online Resource 1. Meta-analytic estimates of additive genetic (A), common or shared environmental (C) and unique or nonshared environmental (E) variance. Estimates from Blokland et al. (2012) and 3 additional studies, some of which include new imaging phenotypes not included in Blokland et al. 2012; * denotes revised heritability estimate, and ^ denotes new phenotype. The meta-analyses including the additional studies (Batouli et al. 2014; den Braber et al. 2013; Rentería et al. 2014) used the same methodology as Blokland et al. (2012). 3rd third ventricle; AMYG amygdala; bilat bilateral; CB cerebellum; CAUD caudate; cGM cerebral gray matter; CT cortical thickness; cWM cerebral white matter; FR frontal; GM gray matter; GP globus pallidus; HIP hippocampus; ICV intracranial volume; L left; LH left hemisphere; LV lateral ventricle; NA nucleus accumbens; OCC occipital; PAR parietal; PUT putamen; R right; RH right hemisphere; TBV total brain volume; TCV total cerebral volume; TEMP temporal; THAL thalamus; WM white matter. References Batouli, S. A., Sachdev, P. S., Wen, W., Wright, M. J., Ames, D., & Trollor, J. N. (2014). Heritability of brain volumes in older adults: the Older Australian Twins Study. Neurobiol Aging, 35(4), 937.e935-918, doi:10.1016/j.neurobiolaging.2013.10.079. Blokland, G. A., de Zubicaray, G. I., McMahon, K. L., & Wright, M. J. (2012). Genetic and environmental influences on neuroimaging phenotypes: a meta-analytical perspective on twin imaging studies. Twin Res Hum Genet, 15(3), 351-371, doi:10.1017/thg.2012.11. den Braber, A., Bohlken, M. M., Brouwer, R. M., van 't Ent, D., Kanai, R., Kahn, R. S., et al. (2013). Heritability of subcortical brain measures: a perspective for future genomewide association studies. Neuroimage, 83, 98-102, doi:10.1016/j.neuroimage.2013.06.027. Rentería, M. E., Hansell, N. K., Strike, L. T., McMahon, K. L., de Zubicaray, G. I., Hickie, I. B., et al. (2014). Genetic Architecture of Subcortical Brain Regions: Common and Region-Specific Genetic Contributions. Genes, Brain and Behavior, n/a-n/a, doi:10.1111/gbb.12177.