Topic XXII – RNA and Protein Synthesis - Science - Miami

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MIAMI-DADE COUNTY PUBLIC SCHOOLS
Student BYOD Resource Page
BIOLOGY I
Course Code: 200031001
TOPIC XXII: MOLECULAR GENETICS - RNA and Protein Synthesis
Pacing
Date
Traditional 5 days
Block
ESSENTIAL CONTENT
A. RNA Synthesis: Transcription (16.3, 16.5)
1. Role in the cell
2. Comparing RNA and DNA
3. Functions of RNA (types)
4. Codons (mRNA; Start and Stop)
B. Protein Synthesis: Translation (16.5)
1. Ribosomes (rRNA; “P” and “A” sites)
2. Amino Acids (tRNA; Anticodon)
3. Codon table
4. Translation
5. Gene Expression
C. Types of Mutations: (16.4)
1. Types
a. Point
b. Frameshift
c. Chromosomal
2. Effects
a. Harmful (16.8)
b. Beneficial
c. Variation
d. Neutral
Division of Academics – Department of Science
Third Nine Weeks
OBJECTIVES
 Summarize the process of transcription.
 Identify the different types of RNA (mRNA, tRNA, and
rRNA) and explain the structure and function of each. **
 Demonstrate how specific code sequences are
translated into traits through protein synthesis.
 Trace the information flow from DNA to a protein.
 Students will explain the basic processes of transcription
and/or translation, and their roles in the expression of
genes.
 Describe how amino acids are coded.
 Identify that certain chromosomal mutations can lead to
human disorders such as sickle-cell disease.
 List possible mutagens and distinguish between
chemical and physical mutagens.
 Differentiate the cellular processes of DNA
replication, transcription, and/or translation (ALD)
 Students will explain how gene and chromosomal
mutations may or may not result in a phenotypic
change.
 Relate that mutation and genetic recombination
increase genetic variation. (ALD)
2.5 days
03-31-16 to 04-07-16
03-31-16 to 04-07-16
INSTRUCTIONAL TOOLS
Core Text Book: Ch.13
Vocabulary:
DNA, RNA, Transcription, Messenger RNA, Ribosomal
RNA, Transfer RNA, Translation Codon, Anticodon,
Ribosome, Amino Acid, Polypeptide, Protein, Nucleotide,
Helix, Base pairing, Hydrogen bonding, Peptide Bond,
RNA splicing, RNA polymerase
Technology:
1. HHMI: Translation (Basic Detail)
2. Interactive Art: Transcription and Translation
3. Art Review: Point Mutations
4. Data Analysis: Complicated Operon
5. NOVA: RNAi
6. DNA tube: Detailed Explanation of mRNA Translation
7. NOVA: Cracking the Code of Life
8. Bozeman Podcast: Mutations
9. HippoCampus Biology: The Transcription of DNA to
RNA: Overview
10. HippoCampus Biology: Genes Encode Proteins
11. HippoCampus Biology: RNA Structure and Function
HippoCampus Biology: The Initiation of Transcription
12. HippoCampus Biology: Elongation, Termination and
Processing
13. HippoCampus Biology: The Transcription of DNA to
RNA: Summary
14. HippoCampus Biology: Translation, Protein Synthesis:
Overview
15. HippoCampus Biology: Decoding RNA
16. HippoCampus Biology: The Components of
Translation
17. HippoCampus Biology: The Mechanism of Translation
18. HippoCampus Biology: Translation, Protein Synthesis:
Summary
19. Edgenuity
20. Extended Learning Modules
Page 1 of 5
MIAMI-DADE COUNTY PUBLIC SCHOOLS
Student BYOD Resource Page
BIOLOGY I
SC.912.L.16.5
Standard:
SC.912.L.16.3
Course Code: 200031001
RNA and Protein Synthesis
Video
 How a Specific Sequence in a DNA
Molecule is Replicated to Create an
Identical Copy of Itself
Video
 Mutation
 DNA Mutations
 Genetic Disease
Image
 DNA sequence; nature of mutation
 Base pairing errors; generation of
mutations
 Base substitution mutation
 Insertion and deletion mutations
Standard:
SC.912.L.16.4


Standard:
SC.912.L.16.5
Video




Division of Academics – Department of Science
Third Nine Weeks
The Central Dogma: RNA and
Transcription
The Central Dogma: Translation and
the Code
What Is RNA?
RNA Polymerase and Transcription
Simulating the Process of
Transcription With Models
Exceptions to the Rules of
Transcription
 The Cell Cycle: Replication
 The Cell Cycle and DNA
 Introduction: DNA Replication

 The mRNA Template
 What is the Role of RNA?
 How Does RNA Know Where to Start
Coding From a DNA Molecule?
 Introduction: Translation and Protein
Synthesis
 Degenerate Code System
 The Process of Protein Synthesis
 Translating the Message into Protein




Closing Remarks: Transcription of
DNA to Messenger RNA
Gene Expression DNA and RNA
Review of the Processes of
Transcription and Translation of
mRNA
The Standard Deviants School
Biology: RNA: Introduction
Translation
Page 2 of 5
MIAMI-DADE COUNTY PUBLIC SCHOOLS
Student BYOD Resource Page
BIOLOGY I
Course Code: 200031001
Standard:
SC.912.L.16.5
Image

Cell with ribosomes highlighted
Standard:
SC.912.L.16.8
Video


DNA and the Genetics of Cancer
Defining Cancer
Standard:
SC.912.L.16.9
Video


Gene Expression Overview
Amino Acid and the Language of Life




The Role of Genes
Mendel's Laws of Inheritance
Inheritance Patterns
Heredity: How Our Parents' Genes
Affect Us
Basic Facts About Cancer
Obesity
Diabetes
Video



Standard:
HE.912.C.1.7
Audio
Division of Academics – Department of Science
Third Nine Weeks

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Hunting Down the Genes Involved in
Disease
DNA and the Genetics of Cancer
Genetic Disease
Families and Genetic Disease
Genetic Case Study: Addison's
Disease
Cystic Fibrosis


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Risk Factors for Heart Disease
DNA Screening
High & Low Risks for Cancer
High & Low Risks for Cardiovascular
Disease
High & Low Risks for Diabetes
Is Tone Deafness Hereditary?
Can Your Grandfather's Diet Shorten
Your Life?
Page 3 of 5
MIAMI-DADE COUNTY PUBLIC SCHOOLS
Student BYOD Resource Page
BIOLOGY I
Course Code: 200031001
Video
Image

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Science Behind the News: Influenza & Flu Vaccines
Georgia Tech Chemist Designs Molecules That May Stop or Slow Effects of Alzheimer's
NIH Discovers Key to Sickle Cell Cure
California Funds Stem Cell Research and Pushes for Quick Results
For Mixed Race Patients, Few Bone Marrow Donors
Animals, Injected with Human Genes, Are Possible Source of Transplantable Organs
Stem Cells Provide Hope for Heart Failure Patients
New Research May Help People Increase Their Lifespans

Pick Your Poison: Cobra Venom Shows Therapeutic Promise
Division of Academics – Department of Science
Third Nine Weeks
Page 4 of 5
MIAMI-DADE COUNTY PUBLIC SCHOOLS
Learning Goals
BIOLOGY I
Course Code: 200031001
SC.912.L16.3: Describe the basic process of DNA replication and how it relates to the transmission and conservation of the genetic information. ( Cognitive Complexity: Level 3:
Strategic Thinking & Complex Reasoning)
SC.912.L16.5: Explain the basic processes of transcription and translation and how they result in the expression of genes. ( Cognitive Complexity: Level 3: Strategic Thinking &
Complex Reasoning )
SCALE
LEARNING PROGRESSION

I am able to distinguish among the cellular processes of DNA replication,
transcription, and translation.
Using a given DNA nucleotide sequence, trace the pathway
from replication to transcription and translation.
Identify the corresponding protein sequence that will form
based on the original DNA nucleotide sequence and what
could occur if the original DNA sequence was changed in
any way.
Score/Step 5.0

I am able to differentiate the cellular processes of DNA replication, transcription, and
translation.
Create a diagram demonstrating the processes of DNA
replication, transcription and translation. Include descriptions
of each process and how they differ from one another.

I am able to differentiate the cellular processes of DNA replication, transcription, and
translation.
Given a diagram of the processes of DNA replication,
transcription and translation, identify the correct sequence of
each process.

I am able to choose the correct cellular process of DNA replication.
Given a diagram of the components of DNA replication,
identify the correct sequence of replication.

I am able to understand that every organism has hereditary information stored in
DNA that get passed on from one generation to another.
Score/Step 4.0
Score/Step 3.0 Target
(Learning Goal)
Score/Step 2.0
Score/Step 1.0
SAMPLE PROGRESS MONITORING AND ASSESSMENT
ACTIVITIES
Division of Academics – Department of Science
Third Nine Weeks
Page 5 of 5
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