Computed Tomography Physics, Instrumentation and Imaging Module G Required reading for this module is Chapters 11 and 13 of your text. Seeram, Computed Tomography 2nd edition, Saunders/Elsevier. The CT technologist plays an invaluable role in the diagnosis of disease by providing the radiologist with quality CT images, through the careful application of theoretical knowledge and clinical skills. As mentioned in the previous module (F), the technologist controls both the scanning and reconstruction processes either through manually selecting scan and reconstruction processes, or selecting the correct preprogrammed “protocols”. This module will initially provide information on these “selectable scan factors”, and then discuss some of the image quality factors, such as geometric and contrast resolution, presented in Module F. SELECTABLE SCAN FACTORS Let’s begin the discussion by explaining the importance of the scan field of view or SFOV. The SFOV is the size of the field in the gantry aperture. It refers to the area of anatomical interest. Remember that this is where data for image reconstruction is gathered. When selecting this scan parameter, the technologist is essentially telling the detectors which data to use and which data to ignore. The SFOV determines the number of detectors required to collect data for a particular procedure, and should be larger that the area of interest. The complete anatomical area must be included in the SFOV in order to avoid the production of out-of-field artifacts. Out-of-field artifacts can present as streaking, shading, or the miss-assignment of CT numbers. Any tissue located outside of the “field” will not be used in the reconstruction process. CT scanners in use today, normally provide pre-selected settings for such procedures as those for CT of the head (pediatric head, small, medium, and large adult heads). Body CT selections should be based on patient size and are usually regarded as the following: Small = 25 cm Medium = 35 cm Large = 48 cm X-large = 50 cm If the scanner has the choices listed above, the technologist should be especially mindful to set the parameter, so as to include all of the patient’s anatomy without setting the field either too small or too large. Too large a SFOV may also produces artifacts, due to the fact that this can also cause shading and streaking at the skin surface. Copyright © Southern Union State Community College, 2007. 1 Some scanners automatically determine the correct SFOV when the technologist positions the lateral lines for the procedure. These settings include calibrations specific to a particular portion of the anatomy. Thus it is very important that these lines are set to include all of the lateral body contours. Remember to select a scan-field-of view that optimizes image quality and minimizes artifacts. The display field of view (DFOV) is the next selectable scan factor to be discussed. The DFOV, also referred to as the reconstructed field of view (RFOV), determines the size of the image viewed on the monitor(s), reproduced, and communicated. The DFOV plus the matrix size, determine the limitations of perceived detail. If selected too large, it reduces the size of the image being displayed. The viewer’s retina senses this, and the perception of detail is reduced. In actuality, the detail of the viewed image is reduced because it is displayed using fewer pixels. The fewer pixels used for display results in each of them being larger; the larger the pixel the less the detail. If set too large, important anatomical information, especially of that located near the skin surface, will be deleted. If selecting both an SFOV and a DFOV, the DFOV must be equal to, or less than the SFOV, never larger. Modern CT scanners allow minimal DFOV selection to be prescribed from the CT scout. The DFOV also impacts image noise and resolution. Wider DFOVs increase the quantity of the photons from which data is retrieved. It reduces the amount of noise present on the image, but at the expense of resolution. This is not the only parameter that affects noise and resolution though. The focal spot size, scanner geometry, detector size, and the reconstruction algorithm, etc. also affect noise and resolution and will be discussed in greater detail later. The manufacturer’s and operator’s goal should be to produce high quality images with excellent resolution and limited noise. Moderate increases in mA usually reduce noise, but at the expense of increased radiation dose to the patient. Patient radiation dose is directly proportional to the mA (tube current). Reducing the mA by half, results in decreasing the radiation dose by half. For example, at 100 mA, the skin exposure is approximately 1.59R. Reducing the mA to 50, results in a skin exposure of .79R. Many of the scanners in use today have the ability to produce more than one set of reconstructed images, using the same raw data. This allows the technologist to use multiple combinations of DFOVs and convolution (reconstruction) filters to produce extremely high quality images. Copyright © Southern Union State Community College, 2007. 2 Reconstruction filters; are primarily responsible for ensuring that the scanned anatomy is accurately represented on the final image secondarily responsible for enhancing the spatial or contrast resolution of the final image, depending on the anatomy scanned if termed High-pass (sharp) filters, provide definitive borders and edges (resulting in increased image noise) – used for high contrast areas – musculoskeletal if termed Low-pass (soft) filters, do not define borders and edges to the extent of the high-pass or sharp filter, so images do not generally exhibit noticeable amounts of noise-used primarily for low contrast areas such as the brain and abdomen The matrix size selection is also a selectable scan factor in most instances. The 512 x 512 matrix size is most common, some equipment allows for the selection of a 1024 x 1024 image matrix. In a 512 x 512 image matrix, there are 262,144 pixels, whereas in a 1024 x 1024 matrix, there are 1,048, 76 pixels. So, you see, references to larger or smaller matrices simply refer to the number of pixels contained within. Smaller matrices, because they contain fewer pixels, reduce the memory requirements of the scanner, allowing faster image reconstruction. Remember, the smaller the pixel, the greater the detail. Pixel size can be calculated for the variable matrices, using the formula: Pixel size = DVOV / Matrix Size Slice thickness is another selectable scan factor. In conventional CT (slice-by-slice acquisition), slice thickness affects perceived detail, because of the effect of volume-averaging for structures with complex shapes. Thinner slices, because of the greater number used to image the anatomy of interest, increase radiation dose to the patient. They should only be used for their value in imaging: 1. areas with complex anatomy and high subject contrast such as the temporal bones and orbits 2. the larynx parathyroid glands, and biliary system Copyright © Southern Union State Community College, 2007. 3 Remember, thin slices are many times quite “noisy”. To compensate for the increased noise, tube output (mA) should be increased moderately. That is if the slices are acquired in conventional fashion. In spiral CT, the selection of thin slices does not result in increased radiation dose, since it is the volume of the area of interest that is acquired during the scanning process, not the slices. The slices are generated by the computer as specified by technologist or protocol selected. What does change increase radiation dose in spiral scanning is pitch. When pitch is doubled, radiation dose is reduced by about half. Changing pitch from 1:1 to 1.5:1 reduces exposure by about 33%. KVp and mA are long-standing scan parameters selected by technologists. In CT, the selectable kVp range is generally between 80 and 140, while mA selections are variable depending on the scanner model and manufacturer. The signal to noise ratio may be improved by increasing the kV, mA, or scan time. Normally only the mA is manipulated. It may be noticed in the clinical setting, that some CT machines automatically increase or decrease the mA, depending on the anatomy being scanned and the desired quality of the image (signal to noise ratio). The scan time, although selectable by the CT technologist, generally range between <1 second to 10 seconds. Short scan times reduce the effects of motion artifacts, and intrinsic motion in the heart and bowel. Short scan times also contribute to patient comfort. As you know, spiral CT with its short scan times, has been well received by both the medical and patient communities. The rate at which a CT machine samples data is selectable at purchase, but effect scan time select ability. The types of sampling, angular and ray, were discussed in an earlier module. A minimum number of samples are required to produce images free of the sampling artifact, aliasing. All of these factors contribute to image quality in CT. Copyright © Southern Union State Community College, 2007. 4 IMAGE QUALITY In Module F some of the factors that contribute to image quality were introduced. These factors are inclusive of: 1. spatial resolution 2. contrast resolution 3. system noise 4. linearity 5. spatial uniformity Spatial resolution is defined as the “degree of blurring in an image” and “the measure of the ability of thee CT scanner to discriminate objects of varying densities located close together, against a uniform background.” To image objects with excellent spatial resolution depends on the slice thickness or section collimation. Spatial resolution can be represented by the Point Spread Function (PSF), Line Spread Function (LSF), and the Modulation Transfer Function (MSF). In CT, the MTF, a mathematically complex formulation, and its associated graphic representations, is generally used to express spatial resolution. A simple definition of the MTF is the expression of the ratio of the fidelity of an image to the original object scanned. An optimal fidelity image has an MTF value of 1, a completed non-optimal image has an MTF of 0, while the majority of CT images fall somewhere between o and 1. The MTF in CT is measured using a line pair phantom in which there are a series descending size bars. The phantom is scanned and spatial resolution is reported in line pairs/mm (lp/mm). The spatial resolution of the CT system is determined by the smallest line pair that can be resolved (seen) on the resultant image. The spaces between the bars and the bars themselves, is called the spatial frequency. The smaller the object, the more spatial frequency is required for scanning. Currently, the optimal resolution that can be obtained from a CT scanner is limited to scanning an object of about 0.3mm. Spatial resolution is also effected by the geometric factors listed in Module F. Contrast resolution, also sometimes referred to as low contrast or tissue resolution, is defined as the ability of as CT scanner “to distinguish material of one composition from another without regard for size or shape.” In other words, it is the ability of the scanner to demonstrate small changes in tissue contrast. It has been reported that this is an area where CT scanners excel, especially as compared to conventional radiography. In CT, absorption of x-ray photons in body tissue is characterized by Hounsfield Units or Linear Attenuation Coefficients (CT numbers), which are a function of the energy of the photons themselves, as well as the atomic number of the body tissue scanned, and its associated mass density. Copyright © Southern Union State Community College, 2007. 5 There is a limitation however. The ability of a CT scanner to image low contrast objects is limited by the: Size of the object Uniformity of the object System noise Noise plays a significant role in image quality. It reduces resolution of low contrast objects. In CT, noise is demonstrated on the images as “graininess”. Noise may also be referred to as quantum mottle or quantum noise. Noise is representative of deviations from the uniformity of the image matrix in which low contrast CT numbers slightly above or below zero (0), are interpreted as 0. Another working definition for noise is the one offered by Stewart Bushong. Dr, Bushong describes noise as “the percent standard deviation of a large number of pixels obtained from a water bath scan.” Researchers agree that noise is dependant on not just one, but several factors, including: kVp and filtration pixel size slice thickness detector efficiency patient dose Patient dose is the ultimate factor that controls noise. According to Bushong, system noise can be defined using the following formula. Copyright © Southern Union State Community College, 2007. 6 CT image noise is one or the parameters that should be measured daily, usually by the technologist. A 20 centimeter water bath phantom is normally used. Scanners are equipped to identify a region of interest (ROI) and to compute the standard deviation of CT numbers within the ROI. The technologist should position the ROI to include a minimum of one hundred (100) pixels, and five determinants; four on the periphery of the ROI and one in the center. Another area where daily checks should be performed is linearity. Linearity is the accuracy of the calibration for a CT scanner. In this area, a special phantom is scanned to check that water measures zero (0). The phantom is called a five-pin performance phantom. After scanning the phantom, the CT system records the values in the phantom; the standard deviation is calculated and plotted. The observed plotline of the CT number and the linear attenuation coefficient should a straight line passing through zero, the CT number for water. This is the linearity, and a deviation from linearity indicates that there is malfunction or misalignment of the scanner. While minor deviations in linearity may not be visible on images, they certainly affect the quantitative analysis of body tissue, since any deviation results in inaccurate CT number generation. Whenever a water bath CT phantom is scanned, the pixel values should be constant in every region of the resultant image. This is termed spatial uniformity and can also be measured or tested. Spatial uniformity is generally tested using an internal software package. This software package allows the plotting of CT numbers along any axis of the image. A histogram or line graph is generated. Acceptable spatial uniformity is exhibited if the histogram or line graph value is within + or- 2 standard deviations of the mean. This module has presented information on “selectable scan factors” and image quality. For further enumeration on these topics, please review the appropriate sections in your text. Module H will provide more information on conventional CT vs. single detector row, and single detector row vs. multi-detector row CT. This workforce solution was funded by a grant awarded under the President’s Community-Based Job Training Grants as implemented by the U.S. Department of Labor’s Employment and Training Administration. 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